Detailed information for compound 559236

Basic information

Technical information
  • TDR Targets ID: 559236
  • Name: 2-[1-(2-chloroethyl)butyl]-1,3-dinitro-5-(tri fluoromethyl)benzene
  • MW: 354.709 | Formula: C13H14ClF3N2O4
  • H donors: 0 H acceptors: 4 LogP: 5.08 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC(c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])CCCl
  • InChi: 1S/C13H14ClF3N2O4/c1-2-3-8(4-5-14)12-10(18(20)21)6-9(13(15,16)17)7-11(12)19(22)23/h6-8H,2-5H2,1H3
  • InChiKey: ILVJTJUIVGKXNQ-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-(1-chlorohexan-3-yl)-1,3-dinitro-5-(trifluoromethyl)benzene
  • fluchloralin
  • AIDS-033043
  • AIDS033043
  • p-Toluidine, N-(2-chloroethyl)-2,6-dinitro-N-propyl-alpha,alpha,alpha-trifluor- o-

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major epsilon tubulin, putative Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major delta tubulin, putative Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major zeta tubulin, putative Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major gamma-tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma cruzi epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania mexicana zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Brugia malayi beta-tubulin, identical Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Trypanosoma cruzi tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Plasmodium vivax tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) alpha-tubulin isotype 2 Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Entamoeba histolytica tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania braziliensis zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Trypanosoma cruzi zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Candida albicans gamma tubulin-like protein Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma brucei zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania major zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Giardia lamblia Epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Trichomonas vaginalis tubulin alpha chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin subunit TubB Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit epsilon Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin epsilon chain Get druggable targets OG5_130726 All targets in OG5_130726
Plasmodium berghei alpha tubulin 2 Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K07374 tubulin alpha, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium berghei alpha tubulin 1 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin, putative Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania infantum beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta-2A chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma brucei tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania infantum delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania donovani alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum alpha tubulin 1 Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma cruzi tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Theileria parva tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Echinococcus granulosus peroxisome assembly protein 26 Get druggable targets OG5_126605 All targets in OG5_126605
Cryptosporidium parvum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi alpha tubulin, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania donovani zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Theileria parva tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin, beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Candida albicans gamma tubulin-like protein Get druggable targets OG5_127652 All targets in OG5_127652
Brugia malayi Tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Theileria parva Tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis peroxisome assembly protein 26 Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii beta-tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium parvum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Trichomonas vaginalis tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium yoelii tubulin beta chain Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum Tubulin alpha-1C chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin beta-4 chain Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii alpha tubulin TUBA1 Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Theileria parva tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium knowlesi tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium yoelii tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus granulosus tubulin epsilon chain Get druggable targets OG5_130726 All targets in OG5_130726
Candida albicans cytoskeletal structural protein Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K07374 tubulin alpha, putative Get druggable targets OG5_126605 All targets in OG5_126605
Babesia bovis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania donovani tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii alpha-tubulin I, putative Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Babesia bovis tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Neospora caninum Beta-tubulin, related Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma cruzi beta tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Cryptosporidium hominis beta-catenin-like repeat protein Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Babesia bovis tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium berghei tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Plasmodium berghei tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii Tubulin/FtsZ family, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma cruzi zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Brugia malayi alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium knowlesi tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania donovani tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi tubulin alpha chain - mouse Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium knowlesi alpha tubulin, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium berghei tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Entamoeba histolytica tubulin alpha-1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum tubulin delta chain, putative Get druggable targets OG5_143817 All targets in OG5_143817
Echinococcus granulosus tubulin gamma 1 chain Get druggable targets OG5_127652 All targets in OG5_127652
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-7 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma congolense tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K10391 tubulin epsilon, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Toxoplasma gondii beta-1 tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum ko:K10389 tubulin gamma, putative Get druggable targets OG5_127652 All targets in OG5_127652
Toxoplasma gondii beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Entamoeba histolytica tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein Get druggable targets OG5_143817 All targets in OG5_143817
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium hominis gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin alpha-3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania mexicana epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania braziliensis epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania donovani epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma mansoni tubulin subunit gamma Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium hominis alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium parvum gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin subunit TubB Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium vivax tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin alpha-2/alpha-4 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Babesia bovis tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi Tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium yoelii tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Plasmodium falciparum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin gamma 1 chain Get druggable targets OG5_127652 All targets in OG5_127652
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium knowlesi alpha-tubulin II, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Echinococcus granulosus tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin beta-4 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum alpha tubulin 2 Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi Tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum tubulin epsilon chain, putative gamma-tubulin 447 aa 479 aa 28.2 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Trypanosoma brucei epsilon tubulin epsilon tubulin, putative 470 aa 488 aa 68.0 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0101 0.0235 0.1246
Trichomonas vaginalis tubulin gamma chain, putative 0.0161 0.0404 0.1958
Trypanosoma brucei alpha tubulin 0.0471 0.1277 0.7456
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0083 0.0083
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0281 0.074 0.4129
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0101 0.0235 0.2943
Onchocerca volvulus Serine\/threonine kinase homolog 0.0586 0.16 0.7824
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0027 0.0025 0.0116
Echinococcus multilocularis L aminoadipate semialdehyde 0.0176 0.0446 0.0446
Plasmodium falciparum endoplasmic reticulum oxidoreductin, putative 0.0051 0.0093 0.0401
Echinococcus granulosus cpg binding protein 0.0031 0.0038 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0607 0.1661 0.8146
Echinococcus granulosus tubulin alpha 0.0351 0.094 0.094
Schistosoma mansoni tubulin subunit alpha 0.0161 0.0404 0.0398
Loa Loa (eye worm) tubulin alpha 2 0.031 0.0823 0.4591
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1277 0.6253
Mycobacterium tuberculosis Probable reductase 0.0667 0.183 0.8968
Mycobacterium tuberculosis Conserved protein 0.0026 0.0022 0.008
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0027 0.0025 0.0025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0235 0.1347
Plasmodium falciparum alpha tubulin 1 0.0471 0.1277 0.7427
Echinococcus granulosus Tubulin alpha 1 chain 0.0471 0.1277 0.1277
Trypanosoma brucei tubulin delta chain 0.0363 0.0972 0.5668
Schistosoma mansoni tubulin subunit beta 0.0625 0.171 0.1706
Echinococcus multilocularis tubulin subunit beta 0.0625 0.171 0.171
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.019 0.0486 0.2363
Schistosoma mansoni tubulin subunit beta 0.0161 0.0404 0.0398
Trichomonas vaginalis tubulin beta chain, putative 0.019 0.0486 0.2363
Echinococcus multilocularis tubulin alpha chain 0.0471 0.1277 0.1277
Trichomonas vaginalis tubulin gamma chain, putative 0.0384 0.1032 0.505
Schistosoma mansoni tubulin subunit alpha 0.0471 0.1277 0.1272
Brugia malayi beta-tubulin, identical 0.0625 0.171 0.958
Echinococcus granulosus dnaJ subfamily B 0.0422 0.114 0.114
Entamoeba histolytica tubulin family protein 0.0625 0.171 1
Leishmania major epsilon tubulin, putative 0.0384 0.1031 0.6014
Schistosoma mansoni alpha tubulin 0.0471 0.1277 0.1272
Trichomonas vaginalis CAMK family protein kinase 0.0586 0.16 0.7845
Echinococcus granulosus L aminoadipate semialdehyde 0.0176 0.0446 0.0446
Trichomonas vaginalis tubulin alpha chain, putative 0.019 0.0486 0.2363
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0667 0.183 0.8968
Echinococcus granulosus expressed protein 0.0034 0.0047 0.0047
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0027 0.0025 0.0111
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0056 0.0056
Loa Loa (eye worm) tubulin beta-4 chain 0.0625 0.171 0.958
Echinococcus multilocularis Tubulin alpha 1 chain 0.0471 0.1277 0.1277
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0056 0.0249
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0129 0.0129
Brugia malayi Tubulin beta-1 chain 0.0625 0.171 0.958
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0027 0.0025 0.0116
Echinococcus granulosus tubulin subunit TubB 0.0471 0.1277 0.1277
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0607 0.1661 0.9713
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0293 0.0774 0.3777
Trichomonas vaginalis tubulin alpha chain, putative 0.0625 0.171 0.8386
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0027 0.0025 0.0253
Plasmodium vivax endoplasmic reticulum oxidoreductin, putative 0.0051 0.0093 0.0401
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0047 0.0204
Loa Loa (eye worm) programmed cell death 8 0.0027 0.0025 0.0111
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0101 0.0235 0.1347
Schistosoma mansoni hypothetical protein 0.0035 0.0048 0.0042
Brugia malayi Inositol-1 0.0039 0.0059 0.0297
Loa Loa (eye worm) beta-tubulin 0.0625 0.171 0.958
Echinococcus granulosus peroxisome assembly protein 26 0.0471 0.1277 0.1277
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0118 0.0547
Echinococcus granulosus tubulin beta 1 chain 0.0625 0.171 0.171
Loa Loa (eye worm) BEN-1 protein 0.0625 0.171 0.958
Trypanosoma brucei epsilon tubulin 0.0384 0.1031 0.6014
Schistosoma mansoni tubulin subunit alpha 0.0471 0.1277 0.1272
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0059 0.031
Trichomonas vaginalis tubulin gamma chain, putative 0.0384 0.1031 0.5043
Echinococcus multilocularis peroxisome assembly protein 26 0.0471 0.1277 0.1277
Echinococcus multilocularis tubulin alpha 1C chain 0.0471 0.1277 0.1277
Trichomonas vaginalis CAMK family protein kinase 0.0586 0.16 0.7845
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0047 0.023
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0056 0.0297
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0363 0.0972 0.5617
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0101 0.0235 0.129
Trypanosoma cruzi zeta tubulin, putative 0.0498 0.1353 0.7906
Entamoeba histolytica thioredoxin reductase, putative 0.0027 0.0025 0.0116
Loa Loa (eye worm) hypothetical protein 0.0471 0.1277 0.7143
Giardia lamblia Beta tubulin 0.0625 0.171 1
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0027 0.0025 0.0025
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0056 0.0297
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0027 0.0025 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0404 0.1958
Loa Loa (eye worm) tubulin beta chain 0.0625 0.171 0.958
Schistosoma mansoni rotamase 0.0034 0.0047 0.0041
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0203 0.0203
Loa Loa (eye worm) tubulin beta-2A chain 0.0625 0.171 0.958
Trichomonas vaginalis set domain proteins, putative 0.0741 0.2038 1
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.005 0.025
Schistosoma mansoni glutamate synthase 0.0027 0.0025 0.002
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1277 0.6253
Brugia malayi serine/threonine-protein kinase plk-2 0.0586 0.16 0.8962
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0235 0.1347
Trichomonas vaginalis tubulin alpha chain, putative 0.0351 0.094 0.4597
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0083 0.0083
Loa Loa (eye worm) thioredoxin reductase 0.0293 0.0774 0.4319
Schistosoma mansoni hypothetical protein 0.0352 0.0943 0.0938
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0101 0.0235 0.1246
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.0022 0.008
Echinococcus granulosus tubulin alpha 1C chain 0.0471 0.1277 0.1277
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0137 0.0131
Echinococcus multilocularis thioredoxin glutathione reductase 0.0295 0.0781 0.0781
Leishmania major beta tubulin 0.0625 0.171 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0101 0.0235 0.023
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0074 0.016 0.0864
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0025 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.0586 0.16 0.7845
Trichomonas vaginalis tubulin alpha chain, putative 0.019 0.0486 0.2363
Onchocerca volvulus 0.019 0.0486 0.2288
Giardia lamblia Epsilon tubulin 0.0193 0.0494 0.2867
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0607 0.1661 0.8146
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0027 0.0025 0.0116
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0059 0.031
Echinococcus granulosus dna polymerase kappa 0.002 0.0006 0.0006
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0586 0.16 0.9355
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0176 0.0446 0.0441
Trypanosoma cruzi tubulin delta chain 0.0363 0.0972 0.5668
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.0022 0.0022
Leishmania major beta tubulin 0.0625 0.171 1
Echinococcus granulosus lysosomal alpha glucosidase 0.0171 0.043 0.043
Trichomonas vaginalis tubulin beta chain, putative 0.0625 0.171 0.8386
Plasmodium falciparum tubulin delta chain, putative 0.0161 0.0404 0.2246
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0607 0.1661 0.8146
Brugia malayi glutamate synthase 0.0027 0.0025 0.0111
Brugia malayi Tubulin gamma chain 0.0384 0.1032 0.5769
Trichomonas vaginalis CAMK family protein kinase 0.0586 0.16 0.7845
Giardia lamblia Thioredoxin reductase 0.0027 0.0025 0.0116
Plasmodium vivax SET domain protein, putative 0.0094 0.0214 0.1122
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0129 0.158
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1277 0.6253
Echinococcus multilocularis microtubule associated protein 2 0.3566 1 1
Loa Loa (eye worm) tubulin alpha-2 chain 0.0471 0.1277 0.7143
Giardia lamblia Glutamate synthase 0.0027 0.0025 0.0116
Trypanosoma brucei tubulin gamma chain 0.0384 0.1032 0.6021
Mycobacterium ulcerans hypothetical protein 0.0026 0.0022 0.0208
Brugia malayi Pre-SET motif family protein 0.0651 0.1785 1
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0027 0.0025 0.0116
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0511
Toxoplasma gondii NADPH-glutathione reductase 0.0101 0.0235 0.1246
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0607 0.1661 0.8146
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.0578 0.3357
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0047 0.0108
Echinococcus multilocularis tubulin alpha 3 chain 0.0471 0.1277 0.1277
Entamoeba histolytica hypothetical protein 0.005 0.0089 0.049
Schistosoma mansoni glutamate synthase 0.0027 0.0025 0.002
Brugia malayi Tubulin alpha-2 chain 0.0471 0.1277 0.7143
Giardia lamblia Alpha-tubulin 0.0471 0.1277 0.7456
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0027 0.0025 0.0253
Trypanosoma cruzi NADH dehydrogenase, putative 0.0027 0.0025 0.0116
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Trypanosoma cruzi tubulin delta chain 0.0363 0.0972 0.5668
Treponema pallidum cell division protein FtsZ 0.0161 0.0404 0.2313
Loa Loa (eye worm) tubulin alpha chain 0.0471 0.1277 0.7143
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Trypanosoma brucei beta tubulin 0.0625 0.171 1
Plasmodium vivax tubulin alpha chain, putative 0.0471 0.1277 0.7427
Plasmodium vivax tubulin alpha chain, putative 0.0471 0.1277 0.7427
Brugia malayi Pre-SET motif family protein 0.0094 0.0214 0.1173
Loa Loa (eye worm) tubulin beta chain 0.0161 0.0404 0.2237
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0129 0.0129
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0083 0.0083
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0027 0.0025 0.0025
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0022 0.0095
Echinococcus granulosus geminin 0.0352 0.0943 0.0943
Plasmodium falciparum tubulin epsilon chain, putative 0.0384 0.1031 0.5967
Echinococcus granulosus Tubulin alpha 1 chain 0.0471 0.1277 0.1277
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0351 0.094 0.5429
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Mycobacterium ulcerans dehydrogenase 0.0027 0.0025 0.0253
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0022 0.0208
Trypanosoma brucei epsilon tubulin 0.0351 0.094 0.5482
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0056 0.0249
Schistosoma mansoni sulfide quinone reductase 0.0027 0.0025 0.002
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0047 0.023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0607 0.1661 0.8146
Echinococcus granulosus tubulin gamma 1 chain 0.0384 0.1032 0.1032
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0044 0.0227
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Schistosoma mansoni alpha-glucosidase 0.0147 0.0363 0.0358
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0047 0.0202
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0025 0.0116
Loa Loa (eye worm) hypothetical protein 0.0176 0.0446 0.2474
Loa Loa (eye worm) hypothetical protein 0.031 0.0823 0.4591
Trichomonas vaginalis tubulin epsilon chain, putative 0.0471 0.1277 0.6253
Brugia malayi Tubulin beta chain 0.019 0.0486 0.2699
Brugia malayi Tubulin alpha-2 chain 0.0471 0.1277 0.7143
Echinococcus granulosus tubulin alpha chain 0.0471 0.1277 0.1277
Echinococcus granulosus histone lysine methyltransferase setb 0.0094 0.0214 0.0214
Echinococcus granulosus tubulin alpha 1C chain 0.0471 0.1277 0.1277
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0094 0.0214 0.0214
Schistosoma mansoni sulfide quinone reductase 0.0027 0.0025 0.002
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0025 0.0097
Trypanosoma brucei alpha tubulin 0.0471 0.1277 0.7456
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0742 0.204 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.005 0.0089 0.0379
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0193 0.0494 0.2783
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0027 0.0025 0.0025
Brugia malayi Tubulin beta chain 0.0161 0.0404 0.2237
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.0214 0.1122
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0586 0.16 0.16
Echinococcus multilocularis tubulin alpha 3 chain 0.0471 0.1277 0.1277
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0101 0.0235 0.2943
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0027 0.0025 0.0116
Trichomonas vaginalis rotamase, putative 0.0034 0.0044 0.019
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.043 0.043
Trypanosoma cruzi epsilon tubulin, putative 0.0384 0.1031 0.6014
Plasmodium vivax glutathione reductase, putative 0.0293 0.0774 0.4444
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0101 0.0235 0.1246
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0129 0.0606
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0586 0.16 0.8962
Trypanosoma brucei alpha tubulin 0.0471 0.1277 0.7456
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0651 0.1785 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0471 0.1277 0.1277
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0044 0.0227
Trypanosoma brucei beta tubulin 0.0625 0.171 1
Trichomonas vaginalis CAMK family protein kinase 0.0586 0.16 0.7845
Entamoeba histolytica hypothetical protein 0.0035 0.0048 0.0249
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0033 0.0154
Trichomonas vaginalis glutaminase, putative 0.0286 0.0756 0.3691
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0027 0.0025 0.0025
Plasmodium falciparum tubulin gamma chain 0.0384 0.1032 0.5975
Schistosoma mansoni tubulin subunit beta 0.0625 0.171 0.1706
Onchocerca volvulus 0.0094 0.0214 0.0939
Trichomonas vaginalis CAMK family protein kinase 0.029 0.0767 0.3744
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0101 0.0235 0.1347
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0235 0.1347
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1277 0.6253
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0089 0.049
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0083 0.0077
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.005 0.0089 0.0379
Entamoeba histolytica disulphide oxidoreductase, putative 0.0027 0.0025 0.0116
Leishmania major beta tubulin 0.0625 0.171 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0214 0.0209
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0101 0.0235 0.1347
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0404 0.1958
Plasmodium falciparum tubulin beta chain 0.0625 0.171 1
Leishmania major beta tubulin 0.0625 0.171 1
Leishmania major beta tubulin 0.0625 0.171 1
Schistosoma mansoni tubulin subunit delta 0.0161 0.0404 0.0398
Loa Loa (eye worm) tubulin beta-1 chain 0.0625 0.171 0.958
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0607 0.1661 0.8146
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0025 0.0116
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0121 0.0121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0607 0.1661 0.8146
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0022 0.0208
Trichomonas vaginalis glutathione reductase, putative 0.0101 0.0235 0.113
Giardia lamblia Delta tubulin 0.0161 0.0404 0.2335
Echinococcus multilocularis tubulin subunit TubB 0.0471 0.1277 0.1277
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0074 0.016 0.0864
Echinococcus granulosus beta tubulin 0.0625 0.171 0.171
Schistosoma mansoni tubulin subunit alpha 0.0471 0.1277 0.1272
Treponema pallidum fructose-bisphosphate aldolase 0.0607 0.1661 1
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0176 0.0446 0.2474
Trypanosoma brucei trypanothione reductase 0.0293 0.0774 0.4508
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0235 0.1347
Echinococcus granulosus tubulin alpha chain 0.0471 0.1277 0.1277
Mycobacterium ulcerans hypothetical protein 0.0027 0.0025 0.0253
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0056 0.0297
Schistosoma mansoni glutamate synthase 0.0027 0.0025 0.002
Toxoplasma gondii beta-1 tubulin, putative 0.0625 0.171 1
Echinococcus multilocularis geminin 0.0352 0.0943 0.0943
Trypanosoma cruzi trypanothione reductase, putative 0.0101 0.0235 0.1347
Schistosoma mansoni hypothetical protein 0.0036 0.005 0.0044
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.171 0.171
Onchocerca volvulus 0.003 0.0033 0.0038
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0056 0.0284
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0056 0.0249
Leishmania major beta tubulin 0.0625 0.171 1
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1277 0.6253
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0027 0.0025 0.0111
Trypanosoma cruzi zeta tubulin, putative 0.0498 0.1353 0.7906
Echinococcus granulosus dna polymerase eta 0.002 0.0006 0.0006
Trypanosoma brucei polo-like protein kinase 0.0586 0.16 0.9355
Trichomonas vaginalis tubulin, putative 0.0194 0.0496 0.2411
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0027 0.0025 0.0097
Trypanosoma cruzi tubulin gamma chain 0.0384 0.1032 0.6021
Trypanosoma brucei beta tubulin 0.0351 0.094 0.5482
Trichomonas vaginalis glutamate synthase, putative 0.0027 0.0025 0.0097
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0059 0.026
Schistosoma mansoni hypothetical protein 0.0027 0.0025 0.002
Schistosoma mansoni tubulin subunit beta 0.0625 0.171 0.1706
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0101 0.0235 0.2943
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0006 0.0006
Schistosoma mansoni tubulin subunit beta 0.0625 0.171 0.1706
Echinococcus multilocularis cpg binding protein 0.0031 0.0038 0.0038
Toxoplasma gondii beta-tubulin, putative 0.0625 0.171 1
Leishmania major trypanothione reductase 0.0293 0.0774 0.4508
Echinococcus granulosus tubulin subunit beta 0.0625 0.171 0.171
Giardia lamblia Fructose-bisphosphate aldolase 0.0607 0.1661 0.9713
Brugia malayi Thioredoxin reductase 0.0293 0.0774 0.4319
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0026 0.0022 0.0208
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0044 0.0227
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0083 0.0432
Echinococcus granulosus tubulin alpha 3 chain 0.0471 0.1277 0.1277
Plasmodium falciparum glutathione reductase 0.0293 0.0774 0.4444
Toxoplasma gondii endoplasmic reticulum oxidoreductin, putative 0.0051 0.0093 0.0401
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0129 0.0614
Loa Loa (eye worm) hypothetical protein 0.0094 0.0214 0.1173
Echinococcus multilocularis Endoplasmic reticulum oxidoreductin 1 0.0051 0.0093 0.0093
Echinococcus granulosus Tubulin alpha 1 chain 0.0471 0.1277 0.1277
Leishmania major zeta tubulin, putative 0.0498 0.1353 0.7906
Loa Loa (eye worm) glutaminase 2 0.0286 0.0756 0.4217
Trypanosoma brucei NADH dehydrogenase 0.0027 0.0025 0.0116
Trichomonas vaginalis tubulin, putative 0.019 0.0486 0.2363
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0048 0.0042
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0044 0.0113
Schistosoma mansoni inositol monophosphatase 0.0039 0.0059 0.0053
Echinococcus multilocularis tubulin epsilon chain 0.0384 0.1031 0.1031
Toxoplasma gondii alpha-tubulin I, putative 0.0471 0.1277 0.7427
Schistosoma mansoni microtubule-associated protein tau 0.3566 1 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0607 0.1661 0.9713
Mycobacterium tuberculosis Probable dehydrogenase 0.0667 0.183 0.8968
Echinococcus multilocularis tubulin alpha chain 0.0471 0.1277 0.1277
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0022 0.0095
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0025 0.0097
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0121 0.0121
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0059 0.0197
Echinococcus granulosus tubulin alpha 3 chain 0.0471 0.1277 0.1277
Leishmania major beta tubulin 0.0625 0.171 1
Plasmodium vivax thioredoxin reductase, putative 0.0293 0.0774 0.4444
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0056 0.0297
Echinococcus multilocularis tubulin alpha chain 0.0471 0.1277 0.1277
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1277 0.6253
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.171 0.171
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0027 0.0025 0.0025
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0101 0.0235 0.1347
Schistosoma mansoni tubulin subunit beta 0.0625 0.171 0.1706
Trypanosoma brucei beta tubulin 0.0625 0.171 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.043 0.043
Brugia malayi glutathione reductase 0.0293 0.0774 0.4319
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0101 0.0235 0.5547
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0059 0.0678
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0027 0.0025 0.0097
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0027 0.0025 0.0097
Trypanosoma brucei pol-associated gene 1 0.0051 0.0093 0.0512
Echinococcus granulosus lysine specific demethylase 5A 0.0062 0.0125 0.0125
Schistosoma mansoni serine/threonine protein kinase 0.0586 0.16 0.1595
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0297 0.0786 0.3774
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0101 0.0235 0.1347
Toxoplasma gondii alpha tubulin TUBA1 0.0471 0.1277 0.7427
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0059 0.0059
Brugia malayi hypothetical protein 0.0035 0.0048 0.0238
Plasmodium falciparum alpha tubulin 2 0.0471 0.1277 0.7427
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0281 0.074 0.3614
Entamoeba histolytica tubulin alpha chain, putative 0.0471 0.1277 0.7456
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0083 0.0432
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0129 0.0723
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.005 0.0089 0.0379
Onchocerca volvulus 0.0176 0.0446 0.2089
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0027 0.0025 0.0116
Trichomonas vaginalis rotamase, putative 0.0034 0.0047 0.0202
Treponema pallidum NADH oxidase 0.0101 0.0235 0.1283
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0083 0.0077
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0027 0.0025 0.0253
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0027 0.0025 0.0097
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0214 0.0209
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0025 0.0116
Entamoeba histolytica hypothetical protein 0.0035 0.0048 0.0249
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0027 0.0025 0.0116
Echinococcus multilocularis dna polymerase kappa 0.002 0.0006 0.0006
Mycobacterium leprae conserved hypothetical protein 0.005 0.0089 0.0317
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0025 0.0116
Trichomonas vaginalis tubulin epsilon chain, putative 0.0625 0.171 0.8386
Mycobacterium ulcerans ferredoxin reductase 0.0027 0.0025 0.0253
Trypanosoma cruzi alpha tubulin, putative 0.0471 0.1277 0.7456
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0044 0.0227
Trichomonas vaginalis CAMK family protein kinase 0.0586 0.16 0.7845
Echinococcus multilocularis tubulin delta chain 0.0161 0.0404 0.0404
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0056 0.0249
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Echinococcus granulosus tubulin beta 4A class IVa 0.0625 0.171 0.171
Brugia malayi Endoplasmic Reticulum Oxidoreductin 1 0.0051 0.0093 0.0491
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0214 0.0209
Echinococcus granulosus tubulin alpha chain 0.0471 0.1277 0.1277
Trichomonas vaginalis CAMK family protein kinase 0.0586 0.16 0.7845
Mycobacterium ulcerans glutaminase 0.0286 0.0756 0.9618
Onchocerca volvulus 0.0099 0.0228 0.1004
Trypanosoma brucei alpha tubulin 0.0471 0.1277 0.7456
Brugia malayi Glycosyl hydrolases family 31 protein 0.0171 0.043 0.2386
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0101 0.0235 0.5547
Mycobacterium ulcerans monoxygenase 0.0027 0.0025 0.0253
Treponema pallidum 4'-phosphopantetheinyl transferase 0.005 0.0089 0.039
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0027 0.0025 0.0025
Echinococcus granulosus thioredoxin glutathione reductase 0.0295 0.0781 0.0781
Leishmania major hypothetical protein, conserved 0.0027 0.0025 0.0116
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0048 0.0048
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0027 0.0025 0.0253
Schistosoma mansoni disulfide oxidoreductase 0.0027 0.0025 0.002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0667 0.183 0.8958
Loa Loa (eye worm) BEN-1 protein 0.0625 0.171 0.958
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0667 0.183 0.8968
Echinococcus granulosus beta tubulin 0.0625 0.171 0.171
Mycobacterium ulcerans NADH dehydrogenase 0.0027 0.0025 0.0253
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0235 0.1347
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.005 0.0089 0.3038
Trichomonas vaginalis tubulin, putative 0.0625 0.171 0.8386
Schistosoma mansoni alpha tubulin 0.0471 0.1277 0.1272
Echinococcus granulosus Endoplasmic reticulum oxidoreductin 1 0.0051 0.0093 0.0093
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0059 0.026
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0101 0.0235 0.1347
Loa Loa (eye worm) inositol-1 0.0039 0.0059 0.0297
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0027 0.0025 0.0116
Leishmania major beta tubulin 0.0625 0.171 1
Trypanosoma brucei beta tubulin 0.0625 0.171 1
Trypanosoma brucei hypothetical protein, conserved 0.0223 0.0578 0.3357
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0097 0.0511
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0161 0.0404 0.1958
Giardia lamblia Beta tubulin 0.0625 0.171 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0101 0.0235 0.1347
Trichomonas vaginalis glutamate synthase, putative 0.0027 0.0025 0.0097
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0027 0.0025 0.0097
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0022 0.0095
Loa Loa (eye worm) tubulin alpha chain 0.0471 0.1277 0.7143
Toxoplasma gondii thioredoxin reductase 0.0293 0.0774 0.4444
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0056 0.0284
Trichomonas vaginalis tubulin alpha chain, putative 0.019 0.0486 0.2363
Trypanosoma brucei zeta tubulin, putative 0.0498 0.1353 0.7906
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0125 0.012
Trypanosoma cruzi endoplasmic reticulum oxidoreductin, putative 0.0051 0.0093 0.0512
Trichomonas vaginalis apoptosis inducing factor, putative 0.0027 0.0025 0.0097
Plasmodium falciparum glutathione reductase 0.0101 0.0235 0.1246
Leishmania major beta tubulin 0.0625 0.171 1
Loa Loa (eye worm) tubulin alpha 2 0.031 0.0823 0.4591
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0056 0.0249
Entamoeba histolytica serine/threonine protein kinase, putative 0.0586 0.16 0.9355
Echinococcus granulosus glutamate synthase 0.0027 0.0025 0.0025
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.005 0.0089 0.041
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0027 0.0025 0.0253
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0025 0.0116
Toxoplasma gondii tubulin, putative 0.0032 0.004 0.0088
Trypanosoma brucei epsilon tubulin 0.0384 0.1031 0.6014
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0059 0.031
Echinococcus multilocularis tubulin alpha 0.0351 0.094 0.094
Echinococcus multilocularis beta tubulin 0.0625 0.171 0.171
Loa Loa (eye worm) glutaminase 0.0286 0.0756 0.4217
Leishmania major beta tubulin 0.0625 0.171 1
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.171 0.171
Trichomonas vaginalis tubulin, putative 0.019 0.0486 0.2363
Plasmodium vivax delta tubulin, putative 0.0161 0.0404 0.2246
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0027 0.0025 0.0025
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0101 0.0235 0.1347
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0025 0.0097
Schistosoma mansoni cpg binding protein 0.0031 0.0038 0.0032
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0742 0.204 1
Trichomonas vaginalis CAMK family protein kinase 0.029 0.0767 0.3744
Leishmania major beta tubulin 0.0625 0.171 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0101 0.0235 0.0235
Leishmania major NADH dehydrogenase, putative 0.0027 0.0025 0.0116
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0083 0.0077
Schistosoma mansoni tubulin subunit gamma 0.0384 0.1032 0.1027
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0121 0.0115
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0027 0.0025 0.0097
Loa Loa (eye worm) glutathione reductase 0.0293 0.0774 0.4319
Echinococcus granulosus tubulin delta chain 0.0161 0.0404 0.0404
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.171 0.171
Entamoeba histolytica tubulin alpha-1 chain 0.0471 0.1277 0.7456
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0059 0.026
Giardia lamblia Alpha-tubulin 0.0471 0.1277 0.7456
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0027 0.0025 0.0111
Mycobacterium ulcerans glutamate synthase subunit beta 0.0027 0.0025 0.0253
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0129 0.158
Echinococcus multilocularis Tubulin alpha 1 chain 0.0471 0.1277 0.1277
Trypanosoma brucei zeta tubulin 0.0498 0.1353 0.7906
Mycobacterium ulcerans hypothetical protein 0.0026 0.0022 0.0208
Schistosoma mansoni cpg binding protein 0.003 0.0033 0.0028
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0025 0.0097
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0025 0.0097
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0129 0.0123
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0056 0.0297
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0586 0.16 0.16
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0027 0.0025 0.0111
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0625 0.171 0.171
Schistosoma mansoni alpha tubulin 0.0471 0.1277 0.1272
Echinococcus granulosus tubulin alpha chain 0.0471 0.1277 0.1277
Trypanosoma cruzi beta tubulin, putative 0.0625 0.171 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0083 0.0083
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0101 0.0235 0.1347
Echinococcus multilocularis dna polymerase eta 0.002 0.0006 0.0006
Echinococcus multilocularis hypothetical protein 0.0471 0.1277 0.1277
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0056 0.0183
Plasmodium falciparum thioredoxin reductase 0.0293 0.0774 0.4444
Leishmania major beta tubulin 0.0625 0.171 1
Onchocerca volvulus 0.0741 0.2038 1
Echinococcus multilocularis tubulin beta 1 chain 0.0625 0.171 0.171
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.171 0.171
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.005 0.0089 0.1686
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.0022 0.0022
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0006 0.0006
Schistosoma mansoni glutaminase 0.0286 0.0756 0.0751
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0059 0.031
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0125 0.012
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.005 0.0089 0.107
Giardia lamblia Beta tubulin 0.0625 0.171 1
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0027 0.0025 0.0116
Brugia malayi Tubulin alpha chain 0.0161 0.0404 0.2237
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0027 0.0025 0.0025
Loa Loa (eye worm) alpha-tubulin 0.0471 0.1277 0.7143
Leishmania major hypothetical protein, conserved 0.0027 0.0025 0.0116
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.005 0.0089 0.107
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0742 0.204 1
Schistosoma mansoni alpha glucosidase 0.0038 0.0056 0.0051
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.171 0.171
Trichomonas vaginalis tubulin gamma chain, putative 0.0625 0.171 0.8386
Leishmania major beta tubulin 0.0625 0.171 1
Mycobacterium leprae cell division protein FtsZ 0.0161 0.0404 0.1878
Schistosoma mansoni inositol monophosphatase 0.0039 0.0059 0.0053
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0048 0.0048
Leishmania major endoplasmic reticulum oxidoreductin, putative 0.0051 0.0093 0.0512
Trypanosoma brucei glucosidase, putative 0.0038 0.0056 0.0297
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0027 0.0025 0.0097
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.005 0.0089 0.0379
Leishmania major beta tubulin 0.0625 0.171 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0171 0.043 0.2386
Brugia malayi alpha-tubulin 0.0471 0.1277 0.7143
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0491
Brugia malayi Cell division protein ftsZ 0.0161 0.0404 0.2237
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0101 0.0235 0.1347
Echinococcus granulosus alpha tubulin 0.0471 0.1277 0.1277
Echinococcus multilocularis tubulin alpha chain 0.0471 0.1277 0.1277
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0101 0.0235 1
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0025 0.0116
Leishmania major beta tubulin 0.0625 0.171 1
Trypanosoma brucei alpha tubulin, putative 0.019 0.0486 0.2818
Mycobacterium tuberculosis Probable oxidoreductase 0.0742 0.204 1
Loa Loa (eye worm) tubulin alpha-3 chain 0.0281 0.074 0.4129
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.0578 0.3357
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Plasmodium vivax tubulin epsilon chain, putative 0.0384 0.1031 0.5967
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0025 0.0097
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0059 0.0875
Schistosoma mansoni cpg binding protein 0.0031 0.0038 0.0032
Schistosoma mansoni kinase 0.0298 0.0789 0.0783
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.171 0.171
Plasmodium vivax tubulin gamma chain, putative 0.0384 0.1032 0.5975
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0056 0.0249
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0297 0.0786 1
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0101 0.0235 0.0235
Mycobacterium ulcerans cell division protein FtsZ 0.0161 0.0404 0.5103
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0101 0.0235 0.1129
Giardia lamblia Kinase, PLK 0.0586 0.16 0.9355
Giardia lamblia NADH oxidase lateral transfer candidate 0.0101 0.0235 0.1347
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Echinococcus multilocularis tubulin alpha chain 0.0471 0.1277 0.1277
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0297 0.0786 0.3834
Brugia malayi tubulin alpha-2 chain 0.0471 0.1277 0.7143
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0097 0.0511
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0056 0.0249
Loa Loa (eye worm) hypothetical protein 0.0036 0.005 0.025
Mycobacterium tuberculosis Cell division protein FtsZ 0.0161 0.0404 0.1957
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0125 0.0672
Brugia malayi jmjC domain containing protein 0.0062 0.0125 0.0672
Leishmania major alpha tubulin 0.0471 0.1277 0.7456
Brugia malayi tubulin alpha chain - mouse 0.0471 0.1277 0.7143
Loa Loa (eye worm) tubulin gamma chain 0.0384 0.1032 0.5769
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0667 0.183 0.8968
Schistosoma mansoni tubulin subunit beta 0.0625 0.171 0.1706
Schistosoma mansoni hypothetical protein 0.0422 0.114 0.1135
Entamoeba histolytica tubulin gamma chain 0.0384 0.1032 0.6021
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0471 0.1277 0.6253
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0094 0.0214 0.0209
Brugia malayi glutaminase DH11.1 0.0286 0.0756 0.4217
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.171 0.171
Trypanosoma cruzi polo-like protein kinase, putative 0.0586 0.16 0.9355
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.171 0.171
Leishmania major beta tubulin 0.0625 0.171 1
Echinococcus multilocularis beta tubulin 0.0625 0.171 0.171
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0027 0.0025 0.0116
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0129 0.0123
Trichomonas vaginalis tubulin epsilon chain, putative 0.0161 0.0404 0.1958
Giardia lamblia Gamma tubulin 0.0384 0.1032 0.6021
Echinococcus multilocularis tubulin gamma 1 chain 0.0384 0.1032 0.1032
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0607 0.1661 0.8146
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0027 0.0025 0.0025
Leishmania major delta tubulin, putative 0.0363 0.0972 0.5668
Entamoeba histolytica hypothetical protein 0.0035 0.0048 0.0249
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0027 0.0025 0.0097
Trichomonas vaginalis mercuric reductase, putative 0.0101 0.0235 0.113
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.171 0.171
Leishmania major hypothetical protein, conserved 0.0223 0.0578 0.3357
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0027 0.0025 0.0025
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.031 0.0823 0.4019
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0027 0.0025 0.0116
Trichomonas vaginalis tubulin epsilon chain, putative 0.0471 0.1277 0.6253
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0027 0.0025 0.0253
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0027 0.0025 0.0116
Echinococcus granulosus tubulin alpha chain 0.0471 0.1277 0.1277
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0101 0.0235 0.1246
Schistosoma mansoni hypothetical protein 0.0352 0.0943 0.0938
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0101 0.0235 0.1246
Entamoeba histolytica hypothetical protein 0.0035 0.0048 0.0249
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0027 0.0025 0.0025
Loa Loa (eye worm) tubulin alpha 2 0.0119 0.0286 0.1576
Plasmodium falciparum thioredoxin reductase 0.0101 0.0235 0.1246
Loa Loa (eye worm) alpha-tubulin 0.0471 0.1277 0.7143
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.0214 0.0214
Brugia malayi CXXC zinc finger family protein 0.003 0.0033 0.0154
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0026 0.0022 0.008
Echinococcus granulosus tubulin epsilon chain 0.0384 0.1031 0.1031
Schistosoma mansoni alpha-glucosidase 0.0147 0.0363 0.0358
Echinococcus multilocularis glutamate synthase 0.0027 0.0025 0.0025
Trichomonas vaginalis tubulin epsilon chain, putative 0.0625 0.171 0.8386
Schistosoma mansoni tubulin subunit epsilon 0.0384 0.1031 0.1026
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0027 0.0025 0.0097
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0027 0.0025 0.0116
Leishmania major gamma-tubulin 0.0384 0.1032 0.6021
Toxoplasma gondii beta tubulin 0.0625 0.171 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0667 0.183 0.8968
Loa Loa (eye worm) alpha-tubulin isotype 2 0.031 0.0823 0.4591
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0111
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0097 0.0511
Echinococcus multilocularis expressed protein 0.0034 0.0047 0.0047
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0056 0.0249
Brugia malayi jmjC domain containing protein 0.0061 0.0121 0.0646
Plasmodium vivax tubulin beta chain, putative 0.0625 0.171 1
Trypanosoma cruzi trypanothione reductase, putative 0.0293 0.0774 0.4508
Schistosoma mansoni ero1-related 0.0051 0.0093 0.0087
Leishmania major phosphopantetheinyl transferase-like protein 0.005 0.0089 0.049
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0121 0.0121
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0059 0.0059
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0056 0.0249
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0027 0.0025 0.0097
Trypanosoma cruzi epsilon tubulin, putative 0.0384 0.1031 0.6014
Echinococcus multilocularis tubulin alpha 1C chain 0.0471 0.1277 0.1277
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0235 0.1347
Trypanosoma cruzi polo-like protein kinase, putative 0.0586 0.16 0.9355
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0044 0.0227
Leishmania major hypothetical protein, conserved 0.0027 0.0025 0.0116
Brugia malayi Tubulin alpha chain 0.0471 0.1277 0.7143
Leishmania major beta tubulin 0.0625 0.171 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0129 0.158
Echinococcus multilocularis dnaJ subfamily B 0.0422 0.114 0.114
Entamoeba histolytica tubulin family protein 0.0625 0.171 1
Leishmania major beta tubulin 0.0625 0.171 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0059 0.031
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0161 0.0404 1
Trypanosoma cruzi NADH dehydrogenase, putative 0.0027 0.0025 0.0116

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Targets
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 26882  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 26953  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 29919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 25756  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 29777  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 25113  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 29099  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 28601  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 24472  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 21739  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 28044  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 21309  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 24440  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 20919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 22594  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 23453  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 21545  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 29554  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 29031  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 23905  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 21179  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 25450  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 22205  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 27459  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 26961  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 22252  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 23996  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 23078  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 20827  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 28024  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 28324  
Annotator: aaronjr@u.washington.edu Comment: Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 7818612

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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