Detailed information for compound 559742

Basic information

Technical information
  • TDR Targets ID: 559742
  • Name: 100631-32-1
  • MW: 148.587 | Formula: C6H9ClO2
  • H donors: 0 H acceptors: 1 LogP: 2.09 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)OC=C.ClC=C
  • InChi: 1S/C4H6O2.C2H3Cl/c1-3-6-4(2)5;1-2-3/h3H,1H2,2H3;2H,1H2
  • InChiKey: HGAZMNJKRQFZKS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 110737-43-4
  • 111643-91-5
  • 113440-63-4
  • 121382-24-9
  • 130123-74-9
  • 131594-89-3
  • 134092-22-1
  • 159814-09-2
  • 182974_ALDRICH
  • 34149-92-3
  • 39310-27-5
  • 39433-77-7
  • 50ME
  • 51990-45-5
  • 54328-26-6
  • 54992-20-0
  • 61037-03-4
  • 69597-97-3
  • 75536-81-1
  • 80342-01-4
  • 81544-85-6
  • 82030-19-1
  • 82030-35-1
  • 82030-95-3
  • 9003-22-9
  • 9066-95-9
  • 92680-82-5
  • 94766-13-9
  • A 15 (Polymer)
  • A 15S
  • A15
  • A15-0
  • acetic acid vinyl ester; chloroethylene
  • ACETIC ACID ETHENYL ESTER POLYMER WITH CHLOROETHENE
  • Acetic acid ethenyl ester polymer with chlorethene (9CI)
  • Acetic acid ethenyl ester, polymer with chloroethene
  • Acetic acid, vinyl ester, polymer with chloroethylene
  • Acetic acid, vinyl ester, chloroethylene copolymer
  • Bakelite LP 70
  • Bakelite VLFV
  • Bakelite VMCC
  • Bakelite VSJD 10
  • Bakelite VYHD
  • Bakelite VYHH
  • Bakelite VYHN
  • Bakelite VYNS
  • Bakelite VYNW
  • Breon 351
  • Breon 425
  • Breon AS 60/41
  • chloroethene; ethenyl ethanoate
  • chloroethene; ethenyl acetate
  • chloroethylene; vinyl acetate
  • Chloroethylenevinyl acetate polymer
  • Corvic 236581
  • Corvic 51/83
  • Corvic R 46/88
  • Denka AC 50
  • Denka vinyl MM 90
  • Denkalac 41M
  • Denkalac 61
  • Diamond shamrock 7401
  • Diamond shamrock 744
  • Disposlips
  • Eslec C
  • Exon 450
  • Exon 454
  • Exon 470
  • Exon 481
  • Exon 760
  • Flovic
  • GEON 100X150
  • GEON 103 ZX
  • GEON 1032X
  • GEON 103EP-J
  • GEON 130X10
  • GEON 135
  • GEON 150XML
  • GEON 351
  • GEON 400X47
  • GEON 421
  • GEON 427
  • GEON 434
  • GEON 440L2
  • GEON 450X150PN
  • Hostaflex VP 150
  • Hostalit PVP
  • Leucovyl PA 1302
  • Lucovyl GA 8502
  • Lucovyl MA 6028
  • Lucovyl PA 1208
  • Marvinol VP 56
  • Norvinyl P 6
  • Opalon 400
  • Pevikon
  • Pevikon C 870
  • Pevikon C870
  • Pliovac AO
  • Pliovic AO
  • poly(vinyl chloride)-poly(vinyl acetate) copolymer
  • Poly(vinylchloride-co-vinylacetate)
  • Polyvinyl chloride-polyvinyl acetate
  • Polyvinyl acetate chloride
  • Polyvinylchloride acetate
  • PVC cordo
  • Resin 4301
  • Rhodopas 6000
  • Rhodopas AX
  • Rhodopas AX 30/10
  • Rhodopas AX 85/15
  • S 2803
  • Sarpifan HP 1
  • Sconatex
  • Solvic 513PB
  • Solvic 523KC
  • Solvic PA 513
  • Solvinc PA 513
  • ST5409964
  • Sumilit PCX
  • Tennus 0565
  • Tygon
  • VA 3 (Copolymer)
  • VAGD
  • VH 10/60
  • Vilit 40
  • Vinnol H 10/60
  • Vinnol H 15/45
  • Vinnol H 40/60
  • Vinyl acetate-vinyl chloride copolymer
  • Vinyl acetate-vinyl chloride polymer
  • Vinyl chloride - vinyl acetate copolymer
  • Vinyl chloride-vinyl acetate copolymer
  • Vinyl chloride-vinyl acetate polymer
  • Vinyl chloride acetate copolymer
  • Vinyl chloride vinyl acetate copolymer
  • vinylchloride-acetate copolymer
  • Vinylite VGHH
  • Vinylite VYDR
  • Vinylite VYDR 21
  • Vinylite VYFS
  • Vinylite VYHD
  • Vinylite VYHH
  • Vinylite VYNS
  • Vinylite VYNW
  • Vinylite vyhh-1
  • Vinyon
  • VLVF
  • VMCC
  • Vygen 220
  • VYHH
  • VYNS
  • VYNW

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) RNA binding protein 0.0253 0.2752 1
Echinococcus multilocularis tumor protein p63 0.0331 0.3798 0.3798
Echinococcus multilocularis expressed conserved protein 0.0091 0.058 0.058
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.03 0.3388 1
Schistosoma mansoni tar DNA-binding protein 0.0253 0.2752 1
Leishmania major mitochondrial DNA polymerase beta 0.03 0.3388 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.1271 0.3643
Onchocerca volvulus 0.0148 0.1349 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0679 0.2422
Loa Loa (eye worm) TAR-binding protein 0.0253 0.2752 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.1213 0.1213
Mycobacterium ulcerans hypothetical protein 0.0158 0.1486 0.5
Schistosoma mansoni tar DNA-binding protein 0.0253 0.2752 1
Brugia malayi RNA recognition motif domain containing protein 0.0253 0.2752 1
Loa Loa (eye worm) hypothetical protein 0.0096 0.0659 0.2349
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0659 0.1398
Schistosoma mansoni tar DNA-binding protein 0.0253 0.2752 1
Echinococcus multilocularis tar DNA binding protein 0.0253 0.2752 0.2752
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0659 0.0659
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0659 0.0978
Loa Loa (eye worm) hypothetical protein 0.0051 0.0046 0.011
Brugia malayi RNA binding protein 0.0253 0.2752 1
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0318 0.1105
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.03 0.3388 1
Schistosoma mansoni tar DNA-binding protein 0.0253 0.2752 1
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0659 1
Brugia malayi hypothetical protein 0.0148 0.1349 0.4236
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.2384 1
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.1213 0.257
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0318 0.0318
Echinococcus granulosus tumor protein p63 0.0331 0.3798 1
Schistosoma mansoni hypothetical protein 0.0071 0.0318 0.1105
Trypanosoma brucei mitochondrial DNA polymerase beta 0.03 0.3388 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0253 0.2752 1
Echinococcus granulosus tar DNA binding protein 0.0253 0.2752 0.6992
Loa Loa (eye worm) hypothetical protein 0.0148 0.1349 0.4872
Toxoplasma gondii hypothetical protein 0.0048 0.0016 0.5
Echinococcus granulosus expressed conserved protein 0.0091 0.058 0.0753
Brugia malayi TAR-binding protein 0.0253 0.2752 1
Schistosoma mansoni tar DNA-binding protein 0.0253 0.2752 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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