Detailed information for compound 560084

Basic information

Technical information
  • TDR Targets ID: 560084
  • Name: 2-Methylphenol sodium salt
  • MW: 131.128 | Formula: C7H8NaO
  • H donors: 0 H acceptors: 1 LogP: 2.58 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]c1ccccc1C.[NaH+]
  • InChi: 1S/C7H8O.Na/c1-6-4-2-3-5-7(6)8;/h2-5,8H,1H3;/q;+1/p-1
  • InChiKey: ONFAAMBUOAGWSG-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

  • 34689-46-8
  • 4549-72-8
  • EINECS 224-914-6
  • o-CRESOL, SODIUM SALT
  • Phenol, 2-methyl-, sodium salt (9CI)
  • Phenol, methyl-, sodium salt
  • sodium 2-methylphenolate
  • Sodium 2-methylphenoxide
  • Sodium o-cresolate
  • Sodium o-cresoxide
  • Sodium o-methylphenolate
  • Sodium o-methylphenoxide
  • Sodium orthocresolate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0105 0.0075
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.005 0.0907 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0616 1
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0616 0.3999
Echinococcus granulosus glutamate synthase 0.0013 0.0095 0.0102
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.3118 0.4502
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.005 0.0907 0.121
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.1398 0.1315
Leishmania major acetoin dehydrogenase e3 component-like protein 0.005 0.0907 0.121
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.1271 0.2404
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0616 0.3999
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0787 0.103
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0365 0.7895 1
Trypanosoma brucei trypanothione reductase 0.0144 0.2993 0.4317
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0105 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.1398 0.194
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0105 0.0075
Leishmania major dihydrolipoamide dehydrogenase, putative 0.005 0.0907 0.121
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.1002 0.1351
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0612 0.077
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1271 0.119
Schistosoma mansoni inositol monophosphatase 0.0037 0.0612 0.0523
Plasmodium vivax hypothetical protein, conserved 0.0072 0.1398 0.4495
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0612 0.1521
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0316 0.6809 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0328 0.7082 0.7054
Schistosoma mansoni cpg binding protein 0.0031 0.0489 0.0398
Loa Loa (eye worm) programmed cell death 8 0.0013 0.0095 0.0175
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0616 0.3999
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0105 0.0075
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.005 0.0907 0.121
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.2004 0.1931
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0907 0.121
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1271 0.119
Loa Loa (eye worm) hypothetical protein 0.0072 0.1398 0.264
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0787 0.103
Brugia malayi hypothetical protein 0.0247 0.5288 1
Onchocerca volvulus 0.0072 0.1398 0.7121
Onchocerca volvulus 0.0072 0.1398 0.7121
Echinococcus multilocularis dnaJ subfamily B 0.0417 0.9061 1
Mycobacterium ulcerans beta-lactamase 0.0072 0.1398 0.3834
Brugia malayi Inositol-1 0.0037 0.0612 0.1157
Brugia malayi CXXC zinc finger family protein 0.0029 0.0452 0.0854
Leishmania major dihydrolipoamide dehydrogenase, putative 0.005 0.0907 0.121
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0616 0.3999
Trichomonas vaginalis mercuric reductase, putative 0.005 0.0907 0.6237
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0612 0.9922
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0612 0.3968
Schistosoma mansoni inositol monophosphatase 0.0037 0.0612 0.0523
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0907 0.121
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.3472 0.383
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0328 0.7082 0.8958
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0612 0.0673
Onchocerca volvulus 0.0096 0.1924 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.005 0.0907 0.2391
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.0095 0.018
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0316 0.6809 1
Mycobacterium tuberculosis Probable reductase 0.0328 0.7082 0.7054
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.1398 0.1315
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.1398 0.3834
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.2004 0.379
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0787 0.103
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.1398 0.1315
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.1398 0.1315
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0616 0.3999
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1271 0.119
Schistosoma mansoni hypothetical protein 0.0417 0.9061 0.907
Toxoplasma gondii hypothetical protein 0.0051 0.0932 0.2887
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0612 0.1783
Plasmodium falciparum thioredoxin reductase 0.005 0.0907 0.2803
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0013 0.0095 0.0102
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0013 0.0095 0.0102
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.118 0.1098
Loa Loa (eye worm) hypothetical protein 0.0072 0.1398 0.264
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.1398 0.1315
Loa Loa (eye worm) TAR-binding protein 0.0066 0.1271 0.24
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0144 0.2993 0.2926
Schistosoma mansoni alpha-glucosidase 0.0142 0.2961 0.2899
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.2004 0.2209
Mycobacterium ulcerans hypothetical protein 0.0166 0.3492 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.005 0.0907 0.2803
Loa Loa (eye worm) beta-lactamase 0.0072 0.1398 0.264
Onchocerca volvulus 0.005 0.092 0.4512
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0616 0.3999
Mycobacterium tuberculosis Probable dehydrogenase 0.0328 0.7082 0.7054
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0907 0.121
Loa Loa (eye worm) glutathione reductase 0.0144 0.2993 0.5658
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.005 0.0907 0.121
Loa Loa (eye worm) hypothetical protein 0.0072 0.1398 0.264
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0616 0.3999
Schistosoma mansoni alpha-glucosidase 0.0142 0.2961 0.2899
Trypanosoma brucei glucosidase, putative 0.0037 0.0616 0.0776
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0105 0.0188
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0616 0.0776
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.005 0.0907 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0365 0.7895 0.7874
Schistosoma mansoni hypothetical protein 0.005 0.092 0.0835
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.1398 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.1033 0.3237
Brugia malayi glutathione reductase 0.0144 0.2993 0.566
Toxoplasma gondii thioredoxin reductase 0.0144 0.2993 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.005 0.0907 0.2391
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.2481 0.4689
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.3472 0.383
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.005 0.0907 0.2803
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.1398 0.1318
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.1271 0.24
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.0095 0.018
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.3472 0.6564
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0013 0.0095 0.018
Treponema pallidum NADH oxidase 0.005 0.0907 1
Mycobacterium leprae conserved hypothetical protein 0.0072 0.1398 0.167
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.5288 0.5835
Brugia malayi beta-lactamase 0.0072 0.1398 0.2643
Loa Loa (eye worm) RNA binding protein 0.0066 0.1271 0.24
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.0095 0.0102
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0907 0.121
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.005 0.0907 0.121
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0616 0.0776
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.005 0.0907 0.0999
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.1398 0.264
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1271 0.119
Mycobacterium tuberculosis Conserved protein 0.0072 0.1398 0.1315
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0616 0.0677
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0527 0.0436
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0616 0.0677
Plasmodium falciparum thioredoxin reductase 0.0144 0.2993 1
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0013 0.0095 0.0102
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.005 0.0907 0.0822
Echinococcus granulosus cpg binding protein 0.0031 0.0489 0.0537
Echinococcus multilocularis cpg binding protein 0.0031 0.0489 0.0537
Leishmania major hypothetical protein, conserved 0.0072 0.1398 0.194
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.2004 0.1931
Trypanosoma cruzi trypanothione reductase, putative 0.0144 0.2993 0.4317
Mycobacterium leprae Probable lipase LipE 0.0072 0.1398 0.167
Schistosoma mansoni survival motor neuron protein 0.005 0.092 0.0835
Trichomonas vaginalis glutathione reductase, putative 0.005 0.0907 0.6237
Loa Loa (eye worm) hypothetical protein 0.0014 0.0105 0.0193
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0037 0.0614 0.1161
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0105 0.0075
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0013 0.0095 0.0102
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0105 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1271 0.119
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0452 0.085
Echinococcus multilocularis tar DNA binding protein 0.0066 0.1271 0.14
Brugia malayi MH2 domain containing protein 0.0121 0.2481 0.4691
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0328 0.7082 0.7054
Echinococcus multilocularis thioredoxin glutathione reductase 0.0144 0.2993 0.3301
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.1398 0.2643
Plasmodium vivax thioredoxin reductase, putative 0.0144 0.2993 1
Brugia malayi beta-lactamase family protein 0.0072 0.1398 0.2643
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.1398 0.1315
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0013 0.0095 0.0102
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0616 0.1797
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0316 0.6809 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0616 0.1165
Trichomonas vaginalis esterase, putative 0.0072 0.1398 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.005 0.0907 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.1398 0.1318
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.1398 0.154
Mycobacterium ulcerans hypothetical protein 0.0072 0.1398 0.3834
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.005 0.0907 0.2803
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0013 0.0095 0.0102
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0037 0.0614 0.1161
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.2004 0.2209
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.005 0.0907 0.2803
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0105 0.0075
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0616 0.116
Loa Loa (eye worm) hypothetical protein 0.0072 0.1398 0.264
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.5288 0.5835
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.005 0.0907 0.082
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.2004 0.3787
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0527 0.0554
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0105 0.0015
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.3472 0.383
Brugia malayi beta-lactamase family protein 0.0072 0.1398 0.2643
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0616 0.3999
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0612 0.077
Toxoplasma gondii NADPH-glutathione reductase 0.005 0.0907 0.2803
Brugia malayi Thioredoxin reductase 0.0144 0.2993 0.566
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.1398 0.154
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.005 0.0907 0.121
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0105 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0616 0.0776
Leishmania major trypanothione reductase 0.0144 0.2993 0.4317
Loa Loa (eye worm) hypothetical protein 0.0247 0.5288 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0907 0.121
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.0095 0.0102
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0612 0.3968
Plasmodium falciparum glutathione reductase 0.005 0.0907 0.2803
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0612 0.3968
Echinococcus granulosus dnaJ subfamily B 0.0417 0.9061 1
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0105 0.0015
Brugia malayi RNA binding protein 0.0066 0.1271 0.2404
Brugia malayi glutamate synthase 0.0013 0.0095 0.018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.2004 0.2209
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.005 0.0907 0.0999
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0105 0.0198
Schistosoma mansoni cpg binding protein 0.0031 0.0489 0.0398
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.2481 0.4689
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.0095 0.0102
Echinococcus granulosus tar DNA binding protein 0.0066 0.1271 0.14
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.005 0.0907 0.121
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0328 0.7082 0.7054
Mycobacterium tuberculosis Conserved protein 0.0072 0.1398 0.1315
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0907 0.121
Onchocerca volvulus 0.0072 0.1398 0.7121
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.1398 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.3472 0.6566
Schistosoma mansoni cpg binding protein 0.0029 0.0452 0.0361
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.005 0.0907 0.2391
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.1398 0.3834
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0612 0.6362
Loa Loa (eye worm) hypothetical protein 0.0072 0.1398 0.264
Mycobacterium tuberculosis Conserved protein 0.0072 0.1398 0.1315
Echinococcus multilocularis glutamate synthase 0.0013 0.0095 0.0102
Loa Loa (eye worm) inositol-1 0.0037 0.0612 0.1153
Onchocerca volvulus 0.0029 0.0452 0.1949
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.2004 0.1931
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.005 0.0907 0.121
Mycobacterium ulcerans lipase LipD 0.0072 0.1398 0.3834
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0105 0.0075
Echinococcus granulosus thioredoxin glutathione reductase 0.0144 0.2993 0.3301
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0328 0.7082 0.7054
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0612 0.077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0907 0.121
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.1398 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0787 0.103
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0149 0.3118 0.4502
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.1398 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0166 0.3492 0.343
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0612 0.0673
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.1398 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0365 0.7895 0.7874
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.1398 0.1315
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0105 0.0075
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.3118 0.4502
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0616 1
Toxoplasma gondii ABC1 family protein 0.0072 0.1398 0.4495
Loa Loa (eye worm) hypothetical protein 0.0072 0.1398 0.264
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.092 0.1741
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.1398 0.194
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0013 0.0095 0.0102
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0612 0.077
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.2004 0.2209
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0105 0.0075
Leishmania major mitochondrial DNA polymerase beta 0.0316 0.6809 1
Plasmodium vivax glutathione reductase, putative 0.0144 0.2993 1
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.1398 0.194
Giardia lamblia NADH oxidase lateral transfer candidate 0.005 0.0907 1
Loa Loa (eye worm) thioredoxin reductase 0.0144 0.2993 0.5658
Schistosoma mansoni alpha glucosidase 0.0037 0.0616 0.0527
Plasmodium falciparum glutathione reductase 0.0144 0.2993 1
Brugia malayi TAR-binding protein 0.0066 0.1271 0.2404
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0013 0.0095 0.0102
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0616 0.3999
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.005 0.0907 0.1716
Loa Loa (eye worm) hypothetical protein 0.0013 0.0095 0.0175
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0365 0.7895 0.7874
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.005 0.0907 0.2803
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0013 0.0095 0.0175
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.0095 0.0102

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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