Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.287 | 0.287 |
Giardia lamblia | PHD finger protein 15 | 0.0028 | 0.0573 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0031 | 0.0732 | 0.0937 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1963 | 0.5833 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1687 | 0.1579 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.287 | 0.5446 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0903 | 0.0903 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1687 | 0.2952 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.1113 | 0.1113 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1972 | 0.5859 |
Echinococcus granulosus | peregrin | 0.0031 | 0.0732 | 0.0611 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0573 | 0.1701 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.2625 | 0.2529 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.1113 | 0.1113 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0.0573 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.1113 | 0.3307 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.287 | 0.287 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.1113 | 0.1741 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.134 | 0.1227 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.287 | 0.8527 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1687 | 0.1687 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1963 | 0.5833 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0903 | 0.1299 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1687 | 0.5013 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.1028 | 0.0911 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.1187 | 0.1897 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0028 | 0.0573 | 0.0573 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0573 | 0.5 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0093 | 0.503 | 0.4965 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1479 | 0.4395 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.1028 | 0.0911 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1963 | 0.3534 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.287 | 0.5446 |
Echinococcus multilocularis | peregrin | 0.0031 | 0.0732 | 0.0611 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.134 | 0.1227 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1687 | 0.1579 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1351 | 0.4014 |
Brugia malayi | RNA binding protein | 0.0062 | 0.287 | 0.5446 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0028 | 0.0573 | 0.045 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.2625 | 0.2529 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.287 | 0.8527 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.287 | 0.2777 |
Echinococcus multilocularis | geminin | 0.0165 | 1 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0128 | 0.0128 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1687 | 0.1687 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.287 | 0.8527 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1192 | 0.3541 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1687 | 0.1687 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.287 | 0.2777 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.287 | 0.287 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0028 | 0.0573 | 0.045 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.2866 | 0.2866 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0028 | 0.0573 | 0.1701 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0573 | 0.5 |
Plasmodium falciparum | phd finger protein, putative | 0.0028 | 0.0573 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.2659 | 0.7899 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1963 | 0.3534 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.3366 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0074 | 0.3711 | 0.3711 |
Brugia malayi | Bromodomain containing protein | 0.0073 | 0.3653 | 0.7097 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0093 | 0.503 | 0.4965 |
Brugia malayi | jmjC domain containing protein | 0.0093 | 0.503 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0903 | 0.2684 |
Onchocerca volvulus | Alhambra homolog | 0.0028 | 0.0573 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.287 | 0.287 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1687 | 0.1579 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0573 | 0.0573 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0573 | 0.0601 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0034 | 0.0985 | 0.0868 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.1113 | 0.0998 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.287 | 0.287 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1687 | 0.1579 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.