Detailed information for compound 56028

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 343.417 | Formula: C20H25NO4
  • H donors: 1 H acceptors: 2 LogP: 3.12 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCO/C(=C/1\C(=NC(=C(C1c1cccc(c1)C)C(=O)OCC)C)C)/O
  • InChi: 1S/C20H25NO4/c1-6-24-19(22)16-13(4)21-14(5)17(20(23)25-7-2)18(16)15-10-8-9-12(3)11-15/h8-11,18,22H,6-7H2,1-5H3/b19-16+
  • InChiKey: GDGRKKVXLYXCIV-KNTRCKAVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.0237 0.3282
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0074
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0034 0.0034
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0426 0.2859 0.2859
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0262 0.0461
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0013 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0369 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0138 0.0846 0.0846
Echinococcus multilocularis glycogen phosphorylase 0.0119 0.0708 0.0708
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.007 0.0365 0.0365
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Echinococcus granulosus Glycosyl transferase family 35 0.0119 0.0708 0.0708
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.029 0.403
Trichomonas vaginalis glycogen phosphorylase, putative 0.0119 0.0708 1
Loa Loa (eye worm) projectin 0.0049 0.022 0.0387
Echinococcus multilocularis titin 0.0049 0.022 0.022
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0067 0.0348 0.0577
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0248
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0016 0.0016
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0044 0.0186 0.0186
Echinococcus granulosus usherin 0.0049 0.022 0.022
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0053 0.0247 0.6638
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.003 0.003
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0013 0.0013
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0034 0.0034
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.007 0.0365 0.0365
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0034 0.0034
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.029 0.029
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0034 0.0034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.022 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0369 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.022 0.0365
Onchocerca volvulus 0.003 0.0086 0.0142
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.003 0.065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0369 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0118 0.0706 0.0706
Brugia malayi bHLH-PAS transcription factor 0.004 0.0155 0.0258
Schistosoma mansoni protein tyrosine phosphatase 0.007 0.0365 0.0365
Schistosoma mansoni tar DNA-binding protein 0.007 0.0366 0.0366
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0138 0.0846 0.0846
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0016 0.0016
Schistosoma mansoni lamin 0.003 0.0086 0.0086
Chlamydia trachomatis glycogen phosphorylase 0.0119 0.0708 1
Toxoplasma gondii exonuclease III APE 0.0021 0.0023 0.0466
Schistosoma mansoni ephrin receptor 0.0049 0.022 0.022
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0013 0.0021
Onchocerca volvulus 0.007 0.0365 0.0647
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.007 0.0365 0.0365
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.007 0.0365 0.9898
Brugia malayi RNA binding protein 0.007 0.0366 0.0607
Loa Loa (eye worm) lethal protein 805 0.0049 0.022 0.0387
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Schistosoma mansoni ap endonuclease 0.0021 0.0023 0.0023
Leishmania major cathepsin L-like protease 0.007 0.0369 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.007 0.0365 0.0365
Onchocerca volvulus Dual oxidase homolog 0.0028 0.0073 0.0119
Schistosoma mansoni coup transcription factor 0.0022 0.0034 0.0034
Leishmania major tyrosine specific protein phosphatase, putative 0.007 0.0365 0.9898
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.003 0.003
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0141 0.0234
Onchocerca volvulus 0.007 0.0365 0.0647
Leishmania major protein-tyrosine phosphatase 1-like protein 0.007 0.0365 0.9898
Loa Loa (eye worm) blistered cuticle protein 3 0.0028 0.0073 0.0129
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0049 0.0219 0.0382
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0007 0.0007
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.007 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0022
Schistosoma mansoni single-minded 0.0053 0.0253 0.0253
Loa Loa (eye worm) CAMK protein kinase 0.0049 0.0224 0.0394
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.007 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0073 0.0129
Onchocerca volvulus 0.0049 0.022 0.0384
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0012
Entamoeba histolytica hypothetical protein 0.0019 0.0013 0.0074
Trypanosoma brucei DNA topoisomerase II beta, putative 0.006 0.03 0.8016
Onchocerca volvulus Peroxidasin homolog 0.0028 0.0073 0.0119
Echinococcus granulosus geminin 0.0171 0.1072 0.1072
Echinococcus multilocularis RUN 0.0022 0.003 0.003
Onchocerca volvulus 0.0049 0.022 0.0384
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Onchocerca volvulus 0.0049 0.022 0.0384
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Loa Loa (eye worm) TAR-binding protein 0.007 0.0366 0.0643
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0118 0.0706 0.0706
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0072 0.1422
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.022 0.0387
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0034 0.0034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0034 0.006
Onchocerca volvulus 0.007 0.0365 0.0647
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0186 0.2544
Echinococcus multilocularis Netrin receptor DCC 0.0049 0.022 0.022
Echinococcus multilocularis cell adhesion molecule 0.0049 0.022 0.022
Brugia malayi hypothetical protein 0.0018 0.0004 0.0006
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.007 0.0365 0.0365
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0034 0.0048
Onchocerca volvulus 0.0057 0.0278 0.0489
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0366 0.0643
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.007 0.0365 0.0365
Entamoeba histolytica glycogenphosphorylase, putative 0.0051 0.0237 0.3282
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0073 0.0122
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0073 0.0129
Onchocerca volvulus 0.007 0.0365 0.0647
Giardia lamblia Glycogen phosphorylase 0.0119 0.0708 1
Onchocerca volvulus 0.007 0.0365 0.0647
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.006 0.03 0.8016
Echinococcus multilocularis 0.007 0.0365 0.0365
Schistosoma mansoni hypothetical protein 0.0049 0.022 0.022
Schistosoma mansoni cell adhesion molecule 0.0049 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Echinococcus multilocularis microtubule associated protein 2 0.1446 1 1
Brugia malayi PXA domain containing protein 0.0019 0.0013 0.0021
Brugia malayi Fibronectin type III domain containing protein 0.0049 0.022 0.0365
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0344 0.0605
Echinococcus granulosus anosmin 1 0.0049 0.022 0.022
Echinococcus multilocularis lamin dm0 0.003 0.0086 0.0086
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0007 0.0012
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0016 0.0027
Brugia malayi Probable DNA topoisomerase II 0.0067 0.0348 0.0577
Schistosoma mansoni nephrin 0.0049 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Leishmania major cytochrome p450-like protein 0.0032 0.01 0.2553
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.007 0.0365 0.0365
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0034 0.0057
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0155 0.0155
Schistosoma mansoni hypothetical protein 0.0022 0.003 0.003
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0049 0.022 0.022
Trypanosoma brucei protein kinase, putative 0.0059 0.029 0.7712
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0022 0.0033 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0073 0.0122
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0344 0.4798
Brugia malayi intermediate filament protein 0.003 0.0086 0.0143
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0034 0.0034
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0034 0.0034
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0023 0.0023
Brugia malayi Peroxidasin 0.0028 0.0073 0.0122
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0186 0.47
Echinococcus granulosus anosmin 1 0.0049 0.022 0.022
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.029 0.7813
Onchocerca volvulus 0.007 0.0365 0.0647
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Echinococcus granulosus cathepsin l1 0.0018 0.0007 0.0007
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.0796 0.1401
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0022
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0044 0.0186 0.0327
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0023 0.0438
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0044 0.0186 0.0186
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0049 0.0219 0.0382
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0022 0.0033 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0007 0.0007
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0013 0.0021
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0016 0.0029
Echinococcus multilocularis transfer RNA-Phe 0.0049 0.022 0.022
Schistosoma mansoni cell adhesion molecule 0.0049 0.022 0.022
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.007 0.0365 0.9898
Echinococcus granulosus EG95 0.0049 0.022 0.022
Onchocerca volvulus 0.007 0.0365 0.0647
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.006
Echinococcus multilocularis cysteine protease 0.0018 0.0007 0.0007
Loa Loa (eye worm) intermediate filament protein 0.003 0.0086 0.0151
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0013 0.0013
Schistosoma mansoni titin 0.0049 0.022 0.022
Leishmania major DNA topoisomerase ii 0.006 0.03 0.8103
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0007 0.0007
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Echinococcus granulosus cell adhesion molecule 0.0049 0.022 0.022
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0034 0.0057
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0369 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0034 0.006
Brugia malayi hypothetical protein 0.007 0.0365 0.0607
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.029 0.403
Schistosoma mansoni tar DNA-binding protein 0.007 0.0366 0.0366
Onchocerca volvulus 0.007 0.0365 0.0647
Schistosoma mansoni glycogen phosphorylase 0.0119 0.0708 0.0708
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0224 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0074
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0013 0.0013
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0012
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.007 0.0365 0.0365
Brugia malayi Cytochrome P450 family protein 0.0032 0.01 0.0166
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0049 0.022 0.0387
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0034 0.0034
Loa Loa (eye worm) myotactin form A 0.0049 0.022 0.0387
Onchocerca volvulus 0.0049 0.022 0.0384
Trichomonas vaginalis DNA topoisomerase II, putative 0.0067 0.0348 0.4853
Schistosoma mansoni nephrin 0.0049 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0028 0.0072 0.0128
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0034 0.0057
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0118 0.0706 0.0706
Schistosoma mansoni cell adhesion molecule 0.0049 0.022 0.022
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0049 0.022 0.0365
Echinococcus granulosus lamin dm0 0.003 0.0086 0.0086
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0034 0.0034
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0118 0.0706 0.0706
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.022 0.0365
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0369 1
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0067 0.0348 0.0348
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0051 0.0237 0.0565
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0034 0.006
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0013 0.0013
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.007 0.0365 0.0365
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.007 0.0365 0.0643
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0074
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0118 0.0706 0.0706
Schistosoma mansoni lipoxygenase 0.0022 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0171 0.1072 0.1072
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0344 0.9302
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.0237 0.3282
Schistosoma mansoni thyroid hormone receptor 0.016 0.1001 0.1001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0023 0.0438
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0034 0.0034
Echinococcus granulosus tumor protein p63 0.0389 0.2605 0.2605
Onchocerca volvulus 0.007 0.0365 0.0647
Loa Loa (eye worm) ctsf protein 0.0018 0.0007 0.0013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.022 0.0365
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0016 0.0016
Echinococcus granulosus Netrin receptor DCC 0.0049 0.022 0.022
Brugia malayi myotactin form A 0.0049 0.022 0.0365
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0044 0.0186 0.0186
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0073 0.0129
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.007 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.003
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.029 0.7813
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0016 0.0016
Echinococcus granulosus Netrin receptor DCC 0.0049 0.022 0.022
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0049 0.022 0.0387
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0034 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0074
Onchocerca volvulus 0.007 0.0365 0.0647
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0426 0.2859 0.2859
Onchocerca volvulus 0.003 0.0086 0.0142
Onchocerca volvulus 0.007 0.0365 0.0647
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0044 0.0186 0.0309
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.007 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0057 0.0278 0.0489
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0072 0.1799
Onchocerca volvulus 0.0049 0.022 0.0384
Loa Loa (eye worm) doublecortin family protein 0.0022 0.003 0.0052
Echinococcus granulosus titin 0.0049 0.0224 0.0224
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0051 0.0237 0.0565
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0007 0.0007
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Echinococcus granulosus nephrin 0.0049 0.022 0.022
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.01 0.2553
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0072 0.1912
Brugia malayi nuclear receptor NHR-88 0.0022 0.0034 0.0057
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0023 0.0226
Brugia malayi Blistered cuticle protein 3 0.0028 0.0073 0.0122
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0013 0.0013
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0072 0.1912
Echinococcus multilocularis roundabout 2 0.0049 0.022 0.022
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Onchocerca volvulus Glycogen phosphorylase homolog 0.0119 0.0708 0.1268
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0118 0.0706 0.0706
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0034 0.0057
Loa Loa (eye worm) hypothetical protein 0.0179 0.1133 0.1994
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0344 0.9302
Onchocerca volvulus 0.007 0.0365 0.0647
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0034 0.0057
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0013
Entamoeba histolytica protein tyrosine phosphatase, putative 0.007 0.0365 0.5105
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0034 0.006
Mycobacterium tuberculosis Probable oxidoreductase 0.0562 0.3815 1
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0013 0.0013
Schistosoma mansoni protein tyrosine phosphatase 0.0118 0.0706 0.0706
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0073 0.0129
Plasmodium vivax DNA gyrase subunit B, putative 0.0022 0.0033 0.0752
Echinococcus granulosus neuroglian 0.0049 0.022 0.022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0369 1
Echinococcus granulosus roundabout 2 0.0049 0.022 0.022
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0118 0.0706 0.0706
Onchocerca volvulus 0.007 0.0365 0.0647
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0034 0.0057
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0044 0.0186 0.2544
Leishmania major mitochondrial DNA topoisomerase II 0.0053 0.0247 0.6638
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.0301 0.0301
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.006
Echinococcus granulosus tar DNA binding protein 0.007 0.0366 0.0366
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0023 0.0041
Trypanosoma brucei Fibronectin type III domain containing protein, putative 0.0049 0.022 0.5688
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0013 0.0013
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0053 0.0247 0.6638
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0186 0.4933
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.007 0.0365 0.0365
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0034 0.0034
Onchocerca volvulus 0.007 0.0365 0.0647
Loa Loa (eye worm) TOPoisomerase family member 0.0067 0.0348 0.0612
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0072 0.1799
Brugia malayi hypothetical protein 0.0022 0.003 0.0049
Loa Loa (eye worm) hypothetical protein 0.0759 0.5194 0.9144
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0022
Schistosoma mansoni neuroglian 0.0049 0.022 0.022
Onchocerca volvulus Chorion peroxidase homolog 0.0028 0.0073 0.0119
Loa Loa (eye worm) RNA binding protein 0.007 0.0366 0.0643
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0007 0.0007
Echinococcus granulosus lamin 0.003 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Onchocerca volvulus 0.007 0.0365 0.0647
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0013 0.0013
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.022 0.0387
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0013 0.0013
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0022 0.0033 0.0752
Echinococcus granulosus G1Y162 protein 0.0049 0.022 0.022
Schistosoma mansoni ap endonuclease 0.0021 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0037 0.0141 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0034 0.0057
Brugia malayi Dual specificity protein phosphatase CDC14B 0.007 0.0365 0.0607
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0186 0.4933
Entamoeba histolytica glycogen phosphorylase, putative 0.0119 0.0708 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Schistosoma mansoni thyroid hormone receptor 0.016 0.1001 0.1001
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0023 0.0466
Echinococcus multilocularis ubiquitin specific protease 41 0.0044 0.0186 0.0186
Schistosoma mansoni polycystin 1-related 0.0022 0.003 0.003
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0344 0.0344
Schistosoma mansoni hypothetical protein 0.0171 0.1072 0.1072
Schistosoma mansoni tar DNA-binding protein 0.007 0.0366 0.0366
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Onchocerca volvulus 0.0049 0.022 0.0384
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0034 0.0034
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0034 0.0034
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0013 0.0013
Onchocerca volvulus 0.0049 0.0224 0.0391
Echinococcus granulosus Fibronectin type III domain containing protein 0.0049 0.022 0.022
Echinococcus granulosus glycogen phosphorylase 0.0119 0.0708 0.0708
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0118 0.0706 0.0706
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0049 0.022 0.022
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0013 0.0013
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0034 0.0034
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Schistosoma mansoni factor for adipocyte differentiation 0.0049 0.022 0.022
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.007 0.0365 0.0365
Trypanosoma cruzi UDP-glucoronosyl and UDP-glucosyl transferase, putative 0.0028 0.0073 0.1814
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Echinococcus multilocularis expressed protein 0.0372 0.2485 0.2485
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.006
Chlamydia trachomatis DNA gyrase subunit B 0.0036 0.0133 0.1483
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0012
Onchocerca volvulus 0.0028 0.0073 0.0119
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0022
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0759 0.5194 0.9144
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0012
Echinococcus granulosus anosmin 1 0.0049 0.022 0.022
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0034 0.0034
Schistosoma mansoni factor for adipocyte differentiation 0.0049 0.022 0.022
Echinococcus multilocularis glycogen phosphorylase 0.0119 0.0708 0.0708
Brugia malayi hypothetical protein 0.0049 0.022 0.0365
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0013 0.0013
Echinococcus multilocularis Netrin receptor DCC 0.0049 0.022 0.022
Brugia malayi Cytochrome P450 family protein 0.0032 0.01 0.0166
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.006
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0044 0.0186 0.2372
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0045 0.0193 0.034
Echinococcus multilocularis anosmin 1 0.0049 0.022 0.022
Echinococcus granulosus RUN 0.0022 0.003 0.003
Echinococcus granulosus contactin 0.0049 0.022 0.022
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0426 0.2859 0.5032
Brugia malayi hypothetical protein 0.0179 0.1133 0.1881
Leishmania major hypothetical protein, conserved 0.0028 0.0072 0.1799
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.007 0.0365 0.5105
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0007 0.0013
Schistosoma mansoni hypothetical protein 0.0138 0.0846 0.0846
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0049 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Schistosoma mansoni hemicentin 0.0049 0.022 0.022
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0816 0.5591 0.5591
Loa Loa (eye worm) hypothetical protein 0.0029 0.0082 0.0145
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0034 0.0057
Schistosoma mansoni lipoxygenase 0.006 0.0301 0.0301
Echinococcus multilocularis lamin 0.003 0.0086 0.0086
Trypanosoma cruzi DNA topoisomerase II, putative 0.006 0.03 0.8103
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.007 0.0365 0.0365
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0034 0.0057
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0262 0.0435
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0044 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0052
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0148 0.0148
Echinococcus multilocularis peroxidasin 0.0028 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0034 0.0034
Echinococcus multilocularis Phosphotidylinositol phosphatase PTPRQ 0.0049 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Leishmania major hypothetical protein, conserved 0.0049 0.022 0.5877
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0264 0.7098
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.01 0.0176
Echinococcus granulosus intermediate filament protein 0.003 0.0086 0.0086
Echinococcus multilocularis anosmin 1 0.0049 0.022 0.022
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0023 0.0226
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.003 0.065
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0224 0.0371
Brugia malayi hypothetical protein 0.007 0.0365 0.0607
Loa Loa (eye worm) hypothetical protein 0.0759 0.5194 0.9144
Brugia malayi SPRY domain containing protein 0.0049 0.022 0.0365
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0034 0.0057
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.007 0.0365 0.0607
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0013 0.0013
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.007 0.0365 0.0365
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0073 0.0122
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Schistosoma mansoni protein tyrosine phosphatase 0.007 0.0365 0.0365
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0426 0.2859 0.2859
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0049 0.022 0.0365
Schistosoma mansoni DNA topoisomerase II 0.0067 0.0348 0.0348
Echinococcus granulosus fibronectin type III domain-containing protein 0.0049 0.022 0.022
Onchocerca volvulus 0.0022 0.0034 0.0048
Loa Loa (eye worm) CYP4Cod1 0.0032 0.01 0.0176
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Trypanosoma brucei DNA topoisomerase ii 0.0053 0.0247 0.6484
Echinococcus multilocularis cysteine protease 0.0018 0.0007 0.0007
Brugia malayi PXA domain containing protein 0.0019 0.0013 0.0021
Onchocerca volvulus 0.0028 0.0073 0.0119
Giardia lamblia DNA topoisomerase II 0.0064 0.0327 0.4431
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0044 0.0186 0.2544
Echinococcus granulosus Fibronectin type III 0.0049 0.022 0.022
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.007 0.0365 0.0365
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.007 0.0365 0.0365
Loa Loa (eye worm) UNCoordinated family member 0.0049 0.022 0.0387
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0013 0.0013
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.007 0.0365 0.0365
Brugia malayi Protein-tyrosine phosphatase 1 0.007 0.0365 0.0607
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0052
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.007 0.0365 0.0365
Giardia lamblia Protein tyrosine phosphatase 0.007 0.0365 0.4992
Onchocerca volvulus Peroxidase homolog 0.0028 0.0073 0.0119
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.006
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0344 0.0344
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.029 0.029
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0013 0.0013
Echinococcus granulosus single minded 2 0.004 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0022
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Brugia malayi protein unc-22 0.0049 0.0224 0.0371
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.022 0.0365
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0013 0.0013
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Brugia malayi nuclear hormone receptor 0.0022 0.0034 0.0057
Leishmania major cathepsin L-like protease 0.007 0.0369 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.029 0.029
Onchocerca volvulus 0.007 0.0365 0.0647
Brugia malayi ecdysteroid receptor 0.0022 0.0034 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.029 0.029
Schistosoma mansoni glycogen phosphorylase 0.0051 0.0237 0.0237
Brugia malayi hypothetical protein 0.0028 0.0073 0.0122
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Schistosoma mansoni titin 0.0049 0.0224 0.0224
Loa Loa (eye worm) protein tyrosine phosphatase 0.007 0.0365 0.0643
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0049 0.022 0.022
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0344 0.927
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0086 0.0151
Schistosoma mansoni protein-tyrosine phosphatase n9 0.007 0.0365 0.0365
Brugia malayi Lethal protein 805 0.0049 0.022 0.0365
Plasmodium falciparum DNA topoisomerase 2 0.0067 0.0348 1
Brugia malayi carbohydrate phosphorylase 0.0119 0.0708 0.1176
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0034 0.0034
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0034 0.0034
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0013 0.0013
Brugia malayi hypothetical protein 0.007 0.0365 0.0607
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0007 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.022 0.5877
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0034 0.006
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0344 0.0344
Onchocerca volvulus 0.007 0.0365 0.0647
Echinococcus multilocularis tumor protein p63 0.0389 0.2605 0.2605
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0118 0.0706 0.0706
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0023 0.0039
Trypanosoma cruzi cruzipain precursor, putative 0.007 0.0369 1
Schistosoma mansoni hypothetical protein 0.0049 0.022 0.022
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0013 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0034 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0369 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0118 0.0706 0.0706
Schistosoma mansoni cell adhesion molecule 0.0049 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.006
Echinococcus granulosus ubiquitin specific protease 41 0.0044 0.0186 0.0186
Trypanosoma brucei cytochrome P450, putative 0.0032 0.01 0.2211
Mycobacterium ulcerans putative regulatory protein 0.004 0.0155 0.0349
Onchocerca volvulus Peroxidase homolog 0.0028 0.0073 0.0119
Echinococcus granulosus peroxidasin 0.0028 0.0073 0.0073
Onchocerca volvulus 0.004 0.0155 0.0268
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.0049 0.022 0.5877
Echinococcus multilocularis usherin 0.0049 0.022 0.022
Schistosoma mansoni tar DNA-binding protein 0.007 0.0366 0.0366
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.029 0.029
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.0049 0.022 0.022
Schistosoma mansoni glycogen phosphorylase 0.0119 0.0708 0.0708
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0034 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.029 0.403
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.022 0.0365
Plasmodium falciparum DNA gyrase subunit B 0.0022 0.0033 0.0752
Trypanosoma brucei protein tyrosine phosphatase 1 0.007 0.0365 0.9894
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.0796 0.1401
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0034 0.0057
Entamoeba histolytica hypothetical protein 0.0019 0.0013 0.0074
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.0278 0.0278
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0118 0.0706 0.0706
Trichomonas vaginalis pten, drome, putative 0.007 0.0365 0.5105
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.022 0.0387
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.003 0.0086 0.0151
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.029 0.7712
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.022 0.0365
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Loa Loa (eye worm) hypothetical protein 0.003 0.0086 0.0151
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.022 0.0365
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0013 0.0013
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Schistosoma mansoni rgs-gaip interacting protein gipc 0.007 0.0365 0.0365
Mycobacterium ulcerans short chain dehydrogenase 0.0562 0.3815 1
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0013 0.0074
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0344 0.0571
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0108 0.0191
Onchocerca volvulus 0.007 0.0365 0.0647
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0013 0.0013
Brugia malayi Fibronectin type III domain containing protein 0.0049 0.022 0.0365
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.022 0.0387
Onchocerca volvulus 0.007 0.0365 0.0647
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.029 0.7813
Loa Loa (eye worm) cysteine protease 0.0018 0.0007 0.0013
Echinococcus granulosus protein tyrosine phosphatase n9 0.007 0.0365 0.0365
Brugia malayi Fibronectin type III domain containing protein 0.0049 0.022 0.0365
Toxoplasma gondii DNA topoisomerase 2, putative 0.0067 0.0348 1
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0067 0.0348 0.0348
Brugia malayi TAR-binding protein 0.007 0.0366 0.0607
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0016 0.0029
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0067 0.0348 0.0577
Loa Loa (eye worm) glycogen phosphorylase 0.0119 0.0708 0.1247
Onchocerca volvulus 0.0028 0.0073 0.0119
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0013 0.0022
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.022 0.0365
Schistosoma mansoni pcd6 interacting protein-related 0.007 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0045 0.0193 0.034
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.003 0.003
Onchocerca volvulus 0.007 0.0365 0.0647
Brugia malayi steroid hormone receptor 0.0022 0.0034 0.0057
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0013 0.0022
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0012
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Echinococcus multilocularis protein tyrosine phosphatase n9 0.007 0.0365 0.0365
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0013 0.0013
Brugia malayi MAP kinase sur-1 0.0059 0.029 0.0481
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Onchocerca volvulus 0.0049 0.022 0.0384
Onchocerca volvulus 0.0049 0.022 0.0384
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0049 0.0219 0.0382
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0044 0.0186 0.0186
Onchocerca volvulus Peroxidasin homolog 0.0028 0.0073 0.0119
Echinococcus multilocularis Glycosyl transferase, family 35 0.0119 0.0708 0.0708
Brugia malayi hypothetical protein 0.0022 0.003 0.0049
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Echinococcus multilocularis anosmin 1 0.0049 0.022 0.022
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0118 0.0706 0.1244
Entamoeba histolytica glycogen phosphorylase, putative 0.0119 0.0708 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0369 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Brugia malayi Protein-tyrosine phosphatase 0.0878 0.6022 1
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.007 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0829 0.5681 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0023 0.0438
Brugia malayi Fibronectin type III domain containing protein 0.0049 0.022 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0369 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.006
Schistosoma mansoni tar DNA-binding protein 0.007 0.0366 0.0366
Brugia malayi Fibronectin type III domain containing protein 0.0049 0.022 0.0365
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0049 0.0224 0.0394
Schistosoma mansoni cell adhesion molecule 0.0049 0.022 0.022
Brugia malayi Doublecortin family protein 0.0022 0.003 0.0049
Echinococcus multilocularis Fibronectin, type III 0.0049 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Brugia malayi hypothetical protein 0.0019 0.0013 0.0021
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.007 0.0365 0.0365
Brugia malayi hypothetical protein 0.0028 0.0072 0.012
Echinococcus granulosus expressed protein 0.0372 0.2485 0.2485
Loa Loa (eye worm) hypothetical protein 0.0055 0.0262 0.0461
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0034 0.0057
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0369 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.01 0.0202
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.007 0.0365 0.0365
Echinococcus multilocularis roundabout 2 0.0049 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0007 0.0007
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.029 0.051
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.029 0.3891
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0013 0.0021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0034 0.0034
Entamoeba histolytica protein tyrosine phosphatase, putative 0.007 0.0365 0.5105
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.007 0.0365 0.0365
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0013 0.0013
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.007 0.0365 0.0365
Brugia malayi hypothetical protein 0.0049 0.022 0.0365
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Brugia malayi hypothetical protein 0.007 0.0365 0.0607
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0034 0.0057
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.007 0.0365 0.0643
Echinococcus multilocularis Fibronectin type III domain containing protein 0.0049 0.022 0.022
Mycobacterium ulcerans DNA gyrase subunit B 0.0022 0.0033 0.0026
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0044 0.0186 0.0186
Entamoeba histolytica hypothetical protein 0.0019 0.0013 0.0074
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Brugia malayi hypothetical protein 0.007 0.0365 0.0607
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.029 0.7813
Onchocerca volvulus 0.007 0.0365 0.0647
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0034 0.0057
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Brugia malayi hypothetical protein 0.0019 0.0013 0.0021
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Schistosoma mansoni rab6-interacting 0.0022 0.003 0.003
Echinococcus multilocularis fibronectin type III domain-containing protein 0.0049 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0022
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0049 0.0224 0.0394
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0007 0.0007
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.007 0.0365 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0369 1
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0072 0.1912
Echinococcus multilocularis hypothetical protein 0.007 0.0365 0.0365
Trypanosoma cruzi DNA topoisomerase II, putative 0.006 0.03 0.8103
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.007 0.0365 0.0643
Echinococcus multilocularis musashi 0.003 0.0086 0.0086
Onchocerca volvulus 0.0022 0.003 0.004
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0044 0.0186 0.4933
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0426 0.2859 0.4747
Schistosoma mansoni titin 0.0049 0.022 0.022
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.0326 0.8824
Onchocerca volvulus 0.0049 0.022 0.0384
Onchocerca volvulus 0.0808 0.5536 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0369 1
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0073 0.0122
Brugia malayi MH2 domain containing protein 0.0131 0.0796 0.1322
Schistosoma mansoni peroxidasin 0.0028 0.0073 0.0073
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.007 0.0365 0.0365
Schistosoma mansoni rab6-interacting 0.0022 0.003 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0369 1
Echinococcus multilocularis roundabout 2 0.0049 0.022 0.022
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.007 0.0365 0.9898
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0118 0.0706 0.0706
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.007 0.0365 0.0365
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0023 0.0226
Echinococcus multilocularis geminin 0.0171 0.1072 0.1072
Schistosoma mansoni lamin 0.003 0.0086 0.0086
Echinococcus multilocularis neuroglian 0.0049 0.022 0.022
Schistosoma mansoni loxhd1 0.0022 0.003 0.003
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0016 0.0016
Brugia malayi Fibronectin type III domain containing protein 0.0049 0.022 0.0365
Onchocerca volvulus 0.0049 0.022 0.0384
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.007 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0044 0.0186 0.2544
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0074
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0118 0.0706 0.0706
Trichomonas vaginalis glycogen phosphorylase, putative 0.0119 0.0708 1
Echinococcus granulosus roundabout 2 0.0049 0.022 0.022
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Onchocerca volvulus 0.0049 0.022 0.0384
Echinococcus granulosus glycogen phosphorylase 0.0119 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0013 0.0013
Schistosoma mansoni tripartite motif protein trim9 0.0049 0.022 0.022
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.022 0.0365
Schistosoma mansoni myosin-binding protein-related 0.0049 0.022 0.022
Loa Loa (eye worm) hypoxia-induced factor 1 0.0165 0.1036 0.1823
Echinococcus granulosus roundabout 2 0.0049 0.022 0.022
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0034 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0034 0.006
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0344 0.9302
Entamoeba histolytica DNA topoisomerase II, putative 0.0067 0.0348 0.4853
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.0049 0.022 0.022
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.003 0.003
Brugia malayi Cytochrome P450 family protein 0.0033 0.0108 0.018
Onchocerca volvulus 4.1 G protein, putative homolog 0.007 0.0365 0.0647
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.029 0.8304
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.01 0.0176
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0034 0.0048
Onchocerca volvulus 0.0022 0.003 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.0301 0.0301
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.022 0.0387
Loa Loa (eye worm) hypothetical protein 0.003 0.0086 0.0151
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0148 0.0148
Schistosoma mansoni peroxidasin 0.0028 0.0073 0.0073
Onchocerca volvulus 0.007 0.0365 0.0647
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0387
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.006
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0013 0.0021
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0049 0.022 0.022
Brugia malayi hypoxia-induced factor 1 0.0165 0.1036 0.172
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.029 0.7813
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0369 1
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.029 0.403
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.0049 0.022 0.5877
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0073 0.0122
Echinococcus multilocularis titin 0.0049 0.0224 0.0224
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0034 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.022 0.0365
Onchocerca volvulus 0.007 0.0365 0.0647
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.01 0.2553
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0049 0.022 0.022
Schistosoma mansoni factor for adipocyte differentiation 0.0049 0.022 0.022
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.029 0.7813
Echinococcus granulosus titin 0.0049 0.0224 0.0224
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0118 0.0706 0.0706
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0262 0.0435
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Echinococcus multilocularis thyroid hormone receptor alpha 0.016 0.1001 0.1001
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0366 0.0607
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0049 0.022 0.0365
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.007 0.0365 0.0365
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0086 0.0143
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0365 0.0607
Echinococcus multilocularis tar DNA binding protein 0.007 0.0366 0.0366
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0049 0.022 0.0387
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Loa Loa (eye worm) hypothetical protein 0.007 0.0365 0.0643
Plasmodium vivax DNA topoisomerase II, putative 0.0067 0.0348 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0023 0.0466
Onchocerca volvulus 0.0049 0.022 0.0384
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.007 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0028 0.0073 0.0129
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0365 0.0643
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.007 0.0365 0.0365
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0013 0.0013
Schistosoma mansoni microtubule-associated protein tau 0.1446 1 1
Brugia malayi myotactin form B 0.0049 0.022 0.0365
Schistosoma mansoni intermediate filament proteins 0.003 0.0086 0.0086
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0022 0.0033 0.0026
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0118 0.0706 0.0706
Brugia malayi Lethal protein 805 0.0049 0.022 0.0365
Loa Loa (eye worm) fibroinase 0.0018 0.0007 0.0013
Leishmania major cathepsin L-like protease 0.007 0.0369 1
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0072 0.1912
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0023 0.0023
Brugia malayi Protein-tyrosine phosphatase 0.007 0.0365 0.0607
Brugia malayi PAS domain containing protein 0.0053 0.0253 0.0419
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.007 0.0365 0.0365

Activities

Activity type Activity value Assay description Source Reference
clogP = 3.69 Calculated partition coefficient (clogP) (PALLAS) ChEMBL. 9154974
I (functional) = 29.7 % Inhibitory effect on L-tri-iodothyronine (L-T3) uptake by human HepG2 hepatoma cells at an application dose 10E-5 M ChEMBL. 9154974
I (functional) = 29.7 % Inhibitory effect on L-tri-iodothyronine (L-T3) uptake by human HepG2 hepatoma cells at an application dose 10E-5 M ChEMBL. 9154974
logP (ADMET) = 3.76 Partition coefficient (logP) ChEMBL. 9154974

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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