Detailed information for compound 56050

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 319.357 | Formula: C19H17N3O2
  • H donors: 2 H acceptors: 3 LogP: 3.07 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC1=C(C(=O)Nc2ccccc2)c2n(CC1)c1c(n2)c(C)ccc1
  • InChi: 1S/C19H17N3O2/c1-12-6-5-9-14-17(12)21-18-16(15(23)10-11-22(14)18)19(24)20-13-7-3-2-4-8-13/h2-9,23H,10-11H2,1H3,(H,20,24)
  • InChiKey: PNMAYYMPUBVBOT-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus GABA-A receptor; anion channel Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 435 aa 29.7 %
Echinococcus granulosus glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Brugia malayi Cation transporter family protein GABA-A receptor; anion channel   467 aa 453 aa 28.5 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 454 aa 29.5 %
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit GABA-A receptor; anion channel   467 aa 379 aa 19.3 %
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative GABA-A receptor; anion channel   467 aa 384 aa 19.5 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 441 aa 33.8 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 461 aa 27.8 %
Echinococcus multilocularis glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 478 aa 28.7 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 447 aa 25.7 %
Onchocerca volvulus Eukaryotic initiation factor 4A-III homolog GABA-A receptor; anion channel   467 aa 453 aa 26.9 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 446 aa 29.1 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 434 aa 26.7 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 446 aa 28.0 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 468 aa 28.6 %
Onchocerca volvulus Large subunit GTPase 1 homolog GABA-A receptor; anion channel   467 aa 496 aa 26.0 %
Echinococcus multilocularis glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Schistosoma mansoni Cys-loop ligand gated ion channel subunit GABA-A receptor; anion channel   467 aa 479 aa 29.2 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog GABA-A receptor; anion channel   467 aa 418 aa 19.6 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 454 aa 30.4 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 494 aa 25.5 %
Echinococcus granulosus glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 439 aa 29.6 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 375 aa 21.9 %
Onchocerca volvulus Gamma-aminobutyric acid receptor subunit beta homolog GABA-A receptor; anion channel   467 aa 433 aa 34.6 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0115 0.0744
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0155 0.134
Brugia malayi Peroxidasin 0.008 0.0344 0.2946
Echinococcus multilocularis neuropeptide receptor A26 0.0455 0.2311 0.6629
Echinococcus granulosus chromobox protein 1 0.0153 0.0728 0.2089
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0542 0.2767 0.2733
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0021 0.0135
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0172 0.1473
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0352 0.4641
Onchocerca volvulus Peroxidase homolog 0.008 0.0344 0.2897
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0032 0.0094 0.0048
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0027 0.0078
Schistosoma mansoni septate junction protein 0.0026 0.0062 0.0177
Echinococcus multilocularis smad 0.0016 0.0011 0.0031
Giardia lamblia DNA damage repair protein 0.0034 0.0103 0.1617
Trypanosoma brucei DNA polymerase kappa, putative 0.0134 0.063 0.8342
Trypanosoma brucei DNA polymerase IV, putative 0.0134 0.063 0.8342
Echinococcus granulosus RUN 0.0019 0.0027 0.0078
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0094 0.1392
Trichomonas vaginalis cation-transporting ATPase, putative 0.0118 0.0544 0.478
Loa Loa (eye worm) RhoGAP domain-containing protein 0.003 0.0087 0.056
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0057 0.0224 0.4244
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0238 0.3127
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0027 0.0115
Brugia malayi Cathepsin L-like precursor 0.0034 0.0104 0.0888
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0064 0.0183
Entamoeba histolytica cysteine proteinase, putative 0.0055 0.0216 0.4088
Brugia malayi hypothetical protein 0.0017 0.0014 0.0116
Brugia malayi protein kinase C3,putative 0.0032 0.0094 0.0802
Echinococcus multilocularis unc 13 (munc13) 0.0037 0.012 0.0343
Brugia malayi hypothetical protein 0.0109 0.0499 0.4266
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0097 0.0825
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0026 0.0062 0.0364
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0076 0.0327 0.0937
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0027 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0021 0.0156
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0036 0.0117 0.0419
Echinococcus granulosus Chromobox protein 3 0.0034 0.0107 0.0306
Schistosoma mansoni hypothetical protein 0.0019 0.0027 0.0078
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.0203 0.2659
Echinococcus multilocularis protein patched 0.0041 0.0142 0.0407
Loa Loa (eye worm) hypothetical protein 0.0026 0.0064 0.0413
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0044 0.0155 0.0445
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0142 0.0407
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0134 0.063 0.5539
Echinococcus granulosus glutathione s transferase mu 0.0025 0.006 0.0172
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.1129 0.324
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0094 0.0269
Leishmania major DNA polymerase kappa, putative 0.0034 0.0103 0.1327
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0093 0.0413 0.5457
Entamoeba histolytica diacylglycerol kinase, putative 0.003 0.0087 0.137
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0087 0.0384 0.1101
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0093 0.0413 0.0616
Schistosoma mansoni peroxidasin 0.008 0.0344 0.0988
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0109 0.1402
Brugia malayi Pleckstrin Homology Domain 0.003 0.0087 0.0741
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0027 0.0078
Brugia malayi Blistered cuticle protein 3 0.008 0.0344 0.2946
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0027 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0055 0.0216 0.1881
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0191 0.0282
Schistosoma mansoni DNA helicase recq5 0.0019 0.0027 0.0077
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.035 0.1003
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0023 0.0045 0.0387
Trypanosoma cruzi cysteine peptidase, putative 0.0055 0.0216 0.032
Loa Loa (eye worm) fibroinase 0.0055 0.0216 0.1403
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0107 0.0911
Echinococcus granulosus intermediate filament protein 0.0026 0.0064 0.0184
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0528
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0062 0.0528
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0528
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.139 0.3987
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0428 0.8513
Trypanosoma brucei DNA polymerase IV, putative 0.0134 0.063 0.8342
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0066 0.0274 0.2393
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0094 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0134 0.063 0.8342
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0021 0.0156
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0032 0.0094 0.0087
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0026 0.0062 0.0528
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0104 0.173
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0755 0.2167
Echinococcus granulosus lamin 0.0026 0.0064 0.0184
Brugia malayi Cathepsin L-like precursor 0.0055 0.0216 0.1851
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.003 0.0087 0.056
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1203
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0075 0.0318 0.2723
Loa Loa (eye worm) heterochromatin protein 1 0.0153 0.0728 0.4726
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0094 0.0136
Loa Loa (eye worm) hypothetical protein 0.0229 0.1128 0.7325
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0044 0.0155 0.1005
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0191 0.0282
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0413
Giardia lamblia DINP protein human, muc B family 0.0115 0.0528 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0233 0.115 0.1552
Brugia malayi Protein kinase domain containing protein 0.0044 0.0155 0.1327
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0027 0.0095
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0023 0.0045 0.0387
Entamoeba histolytica cysteine proteinase 2 0.0039 0.0134 0.2359
Trypanosoma brucei DNA polymerase kappa, putative 0.0134 0.063 0.8342
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0097 0.0348
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0055 0.0216 0.0621
Brugia malayi C1-like domain containing protein 0.0032 0.0094 0.0802
Brugia malayi Cytochrome P450 family protein 0.0025 0.006 0.0513
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Trypanosoma cruzi major cysteine proteinase, putative 0.0109 0.05 0.0746
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0021 0.0061
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0011 0.0031
Brugia malayi RhoGAP domain containing protein 0.003 0.0087 0.0741
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0062 0.0177
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Brugia malayi fibroinase precursor 0.0018 0.0021 0.0181
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Leishmania major calcium motive p-type ATPase, putative 0.0066 0.0274 0.3607
Echinococcus granulosus cathepsin l cysteine peptidase 0.0055 0.0216 0.0621
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0062 0.0518
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0109 0.0929
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0094 0.1204
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0023 0.0045 0.0291
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0021 0.0135
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0027 0.0077
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0208 0.0596
Schistosoma mansoni polycystin 1-related 0.0019 0.0027 0.0078
Trypanosoma brucei unspecified product 0.0075 0.0319 0.4195
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0002 0.0005
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1203
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.139 0.3987
Brugia malayi Papain family cysteine protease containing protein 0.0039 0.0134 0.1145
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Trypanosoma cruzi P-type H+-ATPase, putative 0.0036 0.0117 0.017
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0026 0.0064 0.0896
Loa Loa (eye worm) LGC-31 protein 0.0023 0.0045 0.0291
Loa Loa (eye worm) hypothetical protein 0.0119 0.055 0.3569
Brugia malayi protein kinase C II. 0.008 0.0348 0.2977
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0085 0.0373 0.3268
Leishmania major cytochrome p450-like protein 0.0015 0.0007 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0021 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0412
Loa Loa (eye worm) hypothetical protein 0.0059 0.0238 0.1546
Brugia malayi hypothetical protein 0.0052 0.0199 0.1705
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0034 0.0107 0.0306
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0528
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Echinococcus multilocularis serine:threonine protein kinase N2 0.0044 0.0155 0.0445
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0066 0.0274 0.0787
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0021 0.0181
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0047 0.0172 0.1468
Entamoeba histolytica hypothetical protein 0.0034 0.0107 0.1788
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0178 0.0512
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0111 0.0948
Loa Loa (eye worm) cysteine protease 0.0055 0.0216 0.1403
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0046 0.0032
Loa Loa (eye worm) helicase 0.0034 0.0107 0.069
Brugia malayi p70 ribosomal S6 kinase beta 0.0044 0.0155 0.1327
Brugia malayi Animal haem peroxidase family protein 0.008 0.0344 0.2946
Brugia malayi CXXC zinc finger family protein 0.0028 0.0073 0.0624
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Loa Loa (eye worm) animal heme peroxidase 0.008 0.0344 0.2233
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0094 0.0136
Echinococcus multilocularis lamin 0.0026 0.0064 0.0184
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0023 0.0045 0.0291
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0191 0.3346
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0094 0.027
Mycobacterium ulcerans DNA polymerase IV 0.0134 0.063 0.0623
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0111 0.0318
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0134 0.0384
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0045 0.013
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0104 0.0888
Loa Loa (eye worm) hypothetical protein 0.0025 0.006 0.0387
Entamoeba histolytica hypothetical protein 0.003 0.0087 0.137
Brugia malayi Pre-SET motif family protein 0.003 0.0082 0.0701
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0103 0.1327
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0142 0.0918
Echinococcus granulosus delta-like protein 1 0.0026 0.0062 0.0177
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0177
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0107 0.1788
Entamoeba histolytica hypothetical protein 0.0109 0.0499 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0045 0.0387
Echinococcus multilocularis lamin dm0 0.0026 0.0064 0.0184
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Leishmania major cathepsin L-like protease 0.0055 0.0216 0.2833
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0027 0.0173
Trichomonas vaginalis MYB, putative 0.0086 0.0375 0.3287
Brugia malayi Protein kinase domain containing protein 0.0015 0.0007 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0134 0.063 0.8342
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0073 0.021
Echinococcus granulosus glutathione S transferase Mu 1 0.0397 0.2007 0.5757
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0049 0.0141
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0026 0.0064 0.0057
Trichomonas vaginalis DNA helicase recq, putative 0.0046 0.0169 0.1467
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0075 0.0318 0.2064
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0026 0.0064 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0134 0.063 0.8342
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0027 0.0114
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0007 0.0052
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0021 0.0061
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Brugia malayi Smad1 0.0016 0.0011 0.0094
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0076 0.0327 0.0937
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0177
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0057 0.0224 0.4244
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0021 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0232 0.1141 0.7407
Onchocerca volvulus Chorion peroxidase homolog 0.008 0.0344 0.2897
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0055 0.0216 0.3731
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.0989 0.6417
Echinococcus granulosus cathepsin l1 0.0055 0.0216 0.0621
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0017 0.0014 0.0015
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0085 0.0373 0.7374
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.138 0.716 1
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0093 0.0413 0.1493
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0107 0.1632
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0027 0.0078
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0118 0.0544 0.1561
Echinococcus granulosus neurogenic locus notch protein 4 0.0026 0.0062 0.0177
Brugia malayi Papain family cysteine protease containing protein 0.0055 0.0216 0.1851
Echinococcus granulosus glycine receptor subunit beta 0.0023 0.0045 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0063 0.053
Echinococcus multilocularis cpg binding protein 0.0029 0.0081 0.0233
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Loa Loa (eye worm) hypothetical protein 0.0158 0.0755 0.4899
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0027 0.0078
Trichomonas vaginalis hypothetical protein 0.0034 0.0107 0.0911
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0108 0.0495 0.142
Onchocerca volvulus 0.0026 0.0062 0.0364
Trichomonas vaginalis chromobox protein, putative 0.0097 0.0433 0.3798
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0695 0.9204
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0085 0.0373 0.3268
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0064 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Echinococcus multilocularis fat cadherin tumor suppressor 0.0026 0.0062 0.0177
Onchocerca volvulus 0.0026 0.0064 0.0384
Schistosoma mansoni lamin 0.0026 0.0064 0.0184
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0301 0.0865
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0111 0.0948
Toxoplasma gondii cation-transporting atpase family protein 0.0017 0.0014 0.0047
Schistosoma mansoni smad1 5 8 and 0.0016 0.0011 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0109 0.0929
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0301 0.0865
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0191 0.0548
Brugia malayi MH2 domain containing protein 0.0016 0.0011 0.0094
Onchocerca volvulus 0.0026 0.0062 0.0364
Echinococcus granulosus NDR protein kinase 0.0044 0.0155 0.0445
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0101 0.0458 0.1313
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0155 0.134
Schistosoma mansoni hypothetical protein 0.0679 0.3486 1
Trichomonas vaginalis MYB72, putative 0.0085 0.0373 0.3268
Brugia malayi ImpB/MucB/SamB family protein 0.0158 0.0755 0.6458
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0107 0.0911
Brugia malayi Animal haem peroxidase family protein 0.008 0.0344 0.2946
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0191 0.2494
Loa Loa (eye worm) hypothetical protein 0.0122 0.0564 0.3658
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0109 0.0499 0.143
Trypanosoma brucei trypanothione reductase 0.0092 0.0409 0.54
Echinococcus multilocularis cathepsin b 0.0018 0.0021 0.0061
Schistosoma mansoni nAChR subunit 0.0023 0.0045 0.013
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0007 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0695 0.9204
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0023 0.0045 0.013
Schistosoma mansoni survival motor neuron protein 0.0047 0.0172 0.0494
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Brugia malayi Animal haem peroxidase family protein 0.008 0.0344 0.2946
Echinococcus granulosus cathepsin L 0.0039 0.0134 0.0384
Loa Loa (eye worm) cathepsin B 0.0018 0.0021 0.0135
Plasmodium falciparum calcium-transporting ATPase 0.0101 0.0458 0.8342
Loa Loa (eye worm) hypothetical protein 0.0062 0.0249 0.1616
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0032 0.0094 0.0068
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0135
Echinococcus granulosus calcium transporting atpase 0.0101 0.0458 0.1313
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0109 0.1402
Leishmania major DNA polymerase eta, putative 0.0083 0.0363 0.4785
Brugia malayi notch-like transmembrane receptor 0.0026 0.0062 0.0528
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0111 0.0948
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0118 0.0544 0.1561
Loa Loa (eye worm) hypothetical protein 0.0052 0.0199 0.1291
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0755 0.6464
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Trypanosoma cruzi cysteine peptidase, putative 0.0039 0.0134 0.0196
Echinococcus granulosus dna polymerase eta 0.0158 0.0755 0.2165
Leishmania major cathepsin L-like protease 0.0055 0.0216 0.2833
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0216 0.1881
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0049 0.0141
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0023 0.0045 0.013
Echinococcus multilocularis peroxidasin 0.008 0.0344 0.0988
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0413
Brugia malayi MH1 domain containing protein 0.0016 0.0011 0.0094
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0026 0.0064 0.0844
Leishmania major P-type H -ATPase, putative 0.0053 0.0203 0.2659
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0026 0.0064 0.0229
Onchocerca volvulus 0.003 0.0087 0.0586
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0115 0.0528 0.6988
Echinococcus granulosus neuropeptide receptor A26 0.0455 0.2311 0.6629
Brugia malayi hypothetical protein 0.0019 0.0027 0.0232
Onchocerca volvulus 0.0023 0.0045 0.0216
Plasmodium vivax heterochromatin protein 1, putative 0.0034 0.0107 0.1632
Leishmania major DNA damage repair protein, putative 0.0034 0.0103 0.1327
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0075 0.0634
Schistosoma mansoni chromobox protein 0.0153 0.0728 0.2089
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0032 0.0094 0.0087
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0107 0.0383
Schistosoma mansoni slit 0.0026 0.0062 0.0177
Loa Loa (eye worm) hypothetical protein 0.0034 0.0107 0.069
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0045 0.013
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0064 0.0896
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0118 0.0544 0.1561
Echinococcus granulosus thioredoxin glutathione reductase 0.0092 0.0409 0.1174
Mycobacterium tuberculosis Probable reductase 0.021 0.1027 0.1379
Loa Loa (eye worm) hypothetical protein 0.0034 0.0104 0.0671
Leishmania major cathepsin L-like protease 0.0147 0.0695 0.9204
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0542 0.2767 1
Toxoplasma gondii cathepsin CPL 0.0055 0.0216 0.078
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0023 0.0045 0.013
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0093 0.0413 0.3624
Plasmodium vivax thioredoxin reductase, putative 0.0092 0.0409 0.7416
Echinococcus granulosus neurogenic locus protein delta 0.0026 0.0062 0.0177
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0062 0.0528
Echinococcus multilocularis protein jagged 1 0.0026 0.0062 0.0177
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0023 0.0045 0.013
Loa Loa (eye worm) hypothetical protein 0.0034 0.0107 0.069
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0191 0.0282
Loa Loa (eye worm) hypothetical protein 0.0026 0.0064 0.0413
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0082 0.0235
Onchocerca volvulus 0.0055 0.0216 0.175
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0032 0.0094 0.0269
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0034 0.0107 0.0306
Plasmodium falciparum glutathione reductase 0.0092 0.0409 0.7416
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0107 0.0911
Plasmodium vivax unspecified product 0.0039 0.0134 0.2153
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0082 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0109 0.0929
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0448 0.1285
Loa Loa (eye worm) hypothetical protein 0.003 0.0087 0.056
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0094 0.1392
Toxoplasma gondii P-type ATPase PMA1 0.0053 0.0203 0.0733
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0066 0.0274 0.3607
Schistosoma mansoni atypical protein kinase C 0.0074 0.0315 0.0903
Schistosoma mansoni hypothetical protein 0.0397 0.2007 0.5758
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0097 0.0825
Giardia lamblia Copper-transporting P-type ATPase 0.0026 0.0064 0.0844
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0155 0.2022
Plasmodium falciparum cysteine proteinase falcipain 1 0.0039 0.0134 0.2153
Trypanosoma brucei protein kinase, putative 0.005 0.0191 0.2494
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0044 0.0155 0.1005
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0065 0.0268 0.0397
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0093 0.0413 0.5457
Leishmania major cathepsin L-like protease 0.0147 0.0695 0.9204
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0109 0.0158
Trypanosoma cruzi DNA polymerase kappa, putative 0.0134 0.063 0.0941
Schistosoma mansoni microtubule-associated protein tau 0.067 0.3436 0.9858
Trypanosoma brucei glucosidase, putative 0.0035 0.0111 0.1427
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0007 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0134 0.063 0.8342
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Schistosoma mansoni cpg binding protein 0.0029 0.0081 0.0233
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0021 0.0027
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0021 0.0039 0.0338
Echinococcus granulosus Smad4 0.0016 0.0011 0.0031
Loa Loa (eye worm) ctsf protein 0.0055 0.0216 0.1403
Echinococcus multilocularis X box binding protein 1 0.028 0.1392 0.3993
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0044 0.0155 0.1005
Echinococcus multilocularis cation transporting ATPase 13A3 0.0026 0.0064 0.0183
Echinococcus multilocularis Rac GTPase activating protein 1 0.003 0.0087 0.0248
Entamoeba histolytica cysteine protease, putative 0.0055 0.0216 0.4088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Echinococcus granulosus cathepsin l1 0.0034 0.0104 0.0298
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0036 0.0117 0.0754
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0191 0.0548
Echinococcus multilocularis cathepsin L 0.0039 0.0134 0.0384
Brugia malayi Valyl-tRNA synthetase 0.0034 0.0107 0.0912
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0109 0.0929
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0111 0.0948
Trypanosoma brucei DNA polymerase eta, putative 0.0158 0.0755 1
Schistosoma mansoni hypothetical protein 0.0047 0.0172 0.0494
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Plasmodium vivax unspecified product 0.0021 0.0039 0.035
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0011 0.0031
Echinococcus multilocularis protein kinase c eta type 0.003 0.0087 0.0248
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0528
Trypanosoma brucei rac serine-threonine kinase, putative 0.0044 0.0155 0.2018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0063 0.053
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0091 0.0402 0.341
Brugia malayi Membrane calcium atpase protein 3 0.0076 0.0327 0.2795
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0134 0.2359
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0056 0.0705
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0348 0.0998
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0045 0.013
Mycobacterium tuberculosis Putative ferredoxin reductase 0.021 0.1027 0.1379
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0174
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.003 0.0087 0.0248
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0099 0.0448 0.1285
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0056 0.0468
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0101 0.0458 0.3915
Echinococcus multilocularis glutathione S-transferase 0.0025 0.006 0.0172
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0199 0.0294
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0056 0.0222 0.0248
Echinococcus multilocularis cation transporting atpase worm 0.0026 0.0064 0.0183
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0413 0.8217
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0093 0.0413 0.5457
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0062 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0142 0.1222
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.035 0.1003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Loa Loa (eye worm) hypothetical protein 0.003 0.0087 0.056
Trypanosoma cruzi DNA polymerase kappa, putative 0.0134 0.063 0.0941
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0085 0.0373 0.7374
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0107 0.0911
Brugia malayi glutathione reductase 0.0092 0.0409 0.3501
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0155 0.2022
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0045 0.0387
Leishmania major cathepsin L-like protease 0.0055 0.0216 0.2833
Onchocerca volvulus 0.0055 0.0216 0.175
Schistosoma mansoni cathepsin F (C01 family) 0.0055 0.0216 0.0621
Loa Loa (eye worm) hypothetical protein 0.0034 0.0104 0.0671
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0094 0.0136
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0216 0.1881
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1922 1 1
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0023 0.0045 0.0387
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0023 0.0045 0.013
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0542 0.2767 0.3824
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0094 0.027
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0056 0.0222 0.0215
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0045 0.013
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0064 0.0896
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0045 0.0387
Schistosoma mansoni cathepsin s 0.0021 0.0039 0.0113
Trichomonas vaginalis DNA polymerase eta, putative 0.0134 0.063 0.5539
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0045 0.0387
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0026 0.0064 0.0026
Mycobacterium tuberculosis Probable dehydrogenase 0.021 0.1027 0.1379
Plasmodium vivax vivapain-3 0.0039 0.0134 0.2153
Echinococcus granulosus Chromo domain 0.0034 0.0107 0.0306
Trypanosoma cruzi cysteine protease, putative 0.0039 0.0134 0.0196
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0026 0.0062 0.0177
Echinococcus multilocularis expressed conserved protein 0.009 0.0397 0.1139
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0115 0.0329
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.021 0.1027 0.1379
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0101 0.0458 0.1313
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0155 0.134
Echinococcus granulosus glutathione S transferase 0.002 0.0029 0.0085
Brugia malayi Protein kinase c protein 2 0.0237 0.1169 1
Brugia malayi Variant SH3 domain containing protein 0.003 0.0087 0.0741
Plasmodium falciparum glutathione S-transferase 0.0025 0.006 0.0741
Schistosoma mansoni patched 1 0.0041 0.0142 0.0407
Schistosoma mansoni cpg binding protein 0.0029 0.0081 0.0233
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0023 0.0045 0.013
Schistosoma mansoni atpase class VI type 11c 0.0017 0.0014 0.0039
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0191 0.1656
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0413 0.8217
Trichomonas vaginalis chromobox protein, putative 0.0153 0.0728 0.6406
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0279 0.139 0.3987
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0094 0.0338
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0021 0.0061
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0027 0.0077
Brugia malayi hypothetical protein 0.0019 0.0027 0.0232
Echinococcus multilocularis prostaglandin H2 D isomerase 0.0025 0.006 0.0172
Schistosoma mansoni nAChR subunit 0.0023 0.0045 0.013
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0103 0.1327
Echinococcus granulosus expressed conserved protein 0.009 0.0397 0.1139
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0134 0.2359
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0118 0.0544 0.1561
Loa Loa (eye worm) Smad1 0.0016 0.0011 0.0069
Schistosoma mansoni notch 0.0026 0.0064 0.0182
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0026 0.0064 0.0026
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0061
Trypanosoma cruzi calcium-transporting ATPase, putative 0.004 0.0135 0.0198
Loa Loa (eye worm) hypothetical protein 0.003 0.0087 0.056
Plasmodium vivax vivapain-1 0.0039 0.0134 0.2153
Onchocerca volvulus 0.0028 0.0073 0.0464
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0097 0.0825
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.0203 0.03
Brugia malayi M-phase phosphoprotein, mpp8 0.0122 0.0564 0.4822
Echinococcus multilocularis glutathione S transferase 0.0025 0.006 0.0172
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0155 0.134
Entamoeba histolytica protein kinase, putative 0.0044 0.0155 0.2805
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0094 0.08
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0023 0.0045 0.013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0107 0.0911
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0066 0.0274 0.0407
Echinococcus multilocularis protein jagged 2 0.0026 0.0062 0.0177
Brugia malayi hypothetical protein 0.023 0.1129 0.9664
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0086 0.0375 0.3287
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0695 0.9204
Entamoeba histolytica hypothetical protein 0.0109 0.0499 1
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0155 0.134
Schistosoma mansoni notch 0.0026 0.0062 0.0177
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0007 0.0006
Echinococcus granulosus cation transporting ATPase 13A3 0.0026 0.0064 0.0183
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Leishmania major DNA polymerase eta, putative 0.0158 0.0755 1
Schistosoma mansoni nAChR subunit 0.0023 0.0045 0.013
Schistosoma mansoni protein kinase C mu 0.003 0.0087 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0155 0.0445
Loa Loa (eye worm) hypothetical protein 0.0027 0.0066 0.0428
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0107 0.0911
Brugia malayi Cadherin domain containing protein 0.0026 0.0062 0.0528
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0046 0.0038
Trypanosoma cruzi copper-transporting ATPase, putative 0.0017 0.0014 0.0015
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0023 0.0045 0.013
Onchocerca volvulus 0.0023 0.0045 0.0216
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0085 0.0373 0.3268
Onchocerca volvulus Peroxidase homolog 0.008 0.0344 0.2897
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0001 0.0002
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0037 0.012 0.0343
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0094 0.1204
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0134 0.2359
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Echinococcus multilocularis nAChR subunit 0.0023 0.0045 0.013
Plasmodium falciparum glutathione reductase 0.0032 0.0094 0.1392
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0056 0.0705
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0542 0.2767 0.2761
Echinococcus granulosus protein kinase c epsilon type 0.008 0.0348 0.0998
Loa Loa (eye worm) animal heme peroxidase 0.008 0.0344 0.2233
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0107 0.0911
Echinococcus multilocularis thioredoxin glutathione reductase 0.0092 0.0409 0.1174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0062 0.0518
Schistosoma mansoni hypothetical protein 0.003 0.0087 0.0248
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0026 0.0064 0.0057
Entamoeba histolytica protein kinase, putative 0.0044 0.0155 0.2805
Schistosoma mansoni peroxidasin 0.008 0.0344 0.0988
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0108 0.0495 0.142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0039 0.0134 0.1151
Schistosoma mansoni terminal deoxycytidyl transferase 0.0108 0.0495 0.142
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0035 0.0419
Trypanosoma cruzi trypanothione reductase, putative 0.0092 0.0409 0.0609
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0352 0.4641
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0107 0.0911
Echinococcus multilocularis Chromo domain 0.0034 0.0107 0.0306
Brugia malayi MH2 domain containing protein 0.0016 0.0011 0.0094
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0103 0.015
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Schistosoma mansoni smad1 5 8 and 0.0016 0.0011 0.0031
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0107 0.1632
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0155 0.1343
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0046 0.0563
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0021 0.0156
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0045 0.013
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0014 0.0039
Chlamydia trachomatis metal transport ATPase 0.0026 0.0064 0.0018
Schistosoma mansoni rab6-interacting 0.0019 0.0027 0.0078
Onchocerca volvulus Putative nachr subunit 0.0023 0.0045 0.0216
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Schistosoma mansoni lipoxygenase 0.0054 0.0208 0.0596
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0402 0.3518
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0027 0.0114
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0066 0.0274 0.4993
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1203
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0021 0.0061
Onchocerca volvulus Huntingtin homolog 0.0119 0.055 0.474
Loa Loa (eye worm) calcium ATPase 0.0057 0.0224 0.1451
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Loa Loa (eye worm) hypothetical protein 0.003 0.0085 0.0549
Loa Loa (eye worm) transcription factor SMAD2 0.0235 0.1161 0.7535
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0238 0.3127
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0034 0.0107 0.0383
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0094 0.1204
Schistosoma mansoni notch 0.0026 0.0062 0.0177
Brugia malayi Cytochrome P450 family protein 0.0015 0.0007 0.0064
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0023 0.0045 0.0387
Trypanosoma cruzi DNA polymerase eta, putative 0.0158 0.0755 0.1129
Brugia malayi Papain family cysteine protease containing protein 0.0039 0.0134 0.1145
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0155 0.0446
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0026 0.0064 0.0026
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0274 0.0787
Giardia lamblia High cysteine protein 0.0026 0.0062 0.08
Brugia malayi Cathepsin L-like precursor 0.0021 0.0039 0.0338
Echinococcus multilocularis glutathione S transferase 0.002 0.0029 0.0085
Plasmodium falciparum thioredoxin reductase 0.0032 0.0094 0.1392
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0099 0.0448 0.1285
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0076 0.0327 0.0937
Echinococcus multilocularis tumor protein p63 0.0328 0.1645 0.472
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0142 0.0407
Echinococcus granulosus cation transporting ATPase 13A1 0.0026 0.0064 0.0183
Loa Loa (eye worm) calcium ATPase 0.002 0.0029 0.0189
Schistosoma mansoni serine/threonine kinase 0.0044 0.0155 0.0445
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0107 0.0306
Trichomonas vaginalis set domain proteins, putative 0.0231 0.1135 1
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0023 0.0045 0.013
Loa Loa (eye worm) hypothetical protein 0.0034 0.0107 0.069
Schistosoma mansoni GST class-mu 0.0025 0.006 0.0172
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0027 0.0231
Schistosoma mansoni cathepsin F (C01 family) 0.0055 0.0216 0.0621
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0115 0.0329
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0093 0.0413 0.0616
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0026 0.0064 0.0183
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0103 0.0371
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0004 0.001
Echinococcus multilocularis cathepsin L cysteine protease 0.0055 0.0216 0.0621
Echinococcus granulosus bloom syndrome protein 0.0046 0.0169 0.0486
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1203
Brugia malayi Bloom's syndrome protein homolog 0.0046 0.0169 0.145
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0086 0.0375 0.1354
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0011 0.0031
Echinococcus granulosus Rac GTPase activating protein 1 0.003 0.0087 0.0248
Echinococcus granulosus myotubularin protein 13 0.003 0.0087 0.0248
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1203
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0027 0.0095
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0191 0.2494
Echinococcus granulosus prostaglandin H2 D isomerase 0.0025 0.006 0.0172
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0135
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Brugia malayi MH2 domain containing protein 0.0235 0.1161 0.9931
Brugia malayi hypothetical protein 0.0122 0.0565 0.4838
Schistosoma mansoni loxhd1 0.0019 0.0027 0.0078
Brugia malayi Doublecortin family protein 0.0019 0.0027 0.0232
Echinococcus multilocularis dna polymerase kappa 0.0134 0.063 0.1808
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0021 0.0181
Trypanosoma brucei calcium-translocating P-type ATPase 0.0101 0.0458 0.6044
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0191 0.1656
Onchocerca volvulus 0.0026 0.0062 0.0364
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0046 0.0163
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Schistosoma mansoni ATPase 0.0118 0.0544 0.1561
Echinococcus granulosus dnaJ subfamily B 0.0397 0.2007 0.5758
Brugia malayi Cation transporter family protein 0.0023 0.0045 0.0387
Onchocerca volvulus 0.0055 0.0216 0.175
Brugia malayi Ras association domain family 1 isoform A 0.003 0.0087 0.0741
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0014 0.0047
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0032 0.0094 0.0607
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0093 0.0413 0.1186
Loa Loa (eye worm) thioredoxin reductase 0.0092 0.0409 0.2655
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0155 0.134
Loa Loa (eye worm) hypothetical protein 0.023 0.1129 0.7332
Onchocerca volvulus Peroxidasin homolog 0.008 0.0344 0.2897
Echinococcus multilocularis chromobox protein 1 0.0153 0.0728 0.2089
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0023 0.0045 0.013
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0135
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0094 0.1204
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1203
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0111 0.0948
Echinococcus granulosus notch 0.0026 0.0062 0.0177
Echinococcus granulosus chromobox protein 1 0.0153 0.0728 0.2089
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0023 0.0045 0.0291
Onchocerca volvulus 0.0091 0.0406 0.3451
Loa Loa (eye worm) hypothetical protein 0.0046 0.0169 0.1094
Mycobacterium ulcerans DNA polymerase IV 0.0134 0.063 0.0623
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0064 0.0091
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.021 0.1027 0.1379
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Onchocerca volvulus 0.0037 0.012 0.0884
Brugia malayi Cathepsin L-like precursor 0.0055 0.0216 0.1851
Trypanosoma brucei DNA polymerase kappa, putative 0.0134 0.063 0.8342
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0062 0.0528
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0108 0.0495 0.3212
Onchocerca volvulus Cathepsin L homolog 0.0055 0.0216 0.175
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Loa Loa (eye worm) hypothetical protein 0.003 0.0087 0.056
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0064 0.0896
Loa Loa (eye worm) hypothetical protein 0.0122 0.0565 0.367
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0089 0.0319
Trichomonas vaginalis MYB3r3, putative 0.0085 0.0373 0.3268
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0076 0.0327 0.1179
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0115 0.0329
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0755 0.2167
Echinococcus granulosus smad 0.0016 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Trypanosoma cruzi cruzipain precursor, putative 0.1285 0.6659 1
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0066 0.0274 0.0787
Schistosoma mansoni cpg binding protein 0.0028 0.0073 0.0209
Trypanosoma brucei DNA polymerase kappa, putative 0.0134 0.063 0.8342
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0007 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Echinococcus granulosus phospholipid transporting ATPase VA 0.0017 0.0014 0.0039
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0021 0.0181
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0108 0.0495 0.142
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.0203 0.03
Trichomonas vaginalis cation-transporting ATPase, putative 0.0118 0.0544 0.478
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0027 0.0077
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0134 0.0384
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0156
Brugia malayi intermediate filament protein 0.0026 0.0064 0.0548
Onchocerca volvulus 0.008 0.0344 0.2897
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1922 1 1
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0085 0.0373 0.7374
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0014 0.0015
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0023 0.0045 0.013
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0021 0.0181
Echinococcus granulosus cation transporting atpase worm 0.0026 0.0064 0.0183
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0177
Leishmania major trypanothione reductase 0.0092 0.0409 0.54
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0011 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0082 0.0235
Brugia malayi E1-E2 ATPase family protein 0.0053 0.0203 0.1739
Onchocerca volvulus 0.0122 0.0564 0.4863
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0032 0.0094 0.0269
Leishmania major proton motive ATPase, putative 0.0026 0.0064 0.0805
Brugia malayi diacylglycerol kinase 0.003 0.0087 0.0741
Mycobacterium ulcerans hypothetical protein 0.0034 0.0103 0.0096
Echinococcus multilocularis cysteine protease 0.0055 0.0216 0.0621
Loa Loa (eye worm) hypothetical protein 0.0096 0.0428 0.2774
Plasmodium falciparum copper-transporting ATPase 0.0026 0.0064 0.0818
Brugia malayi Heterochromatin protein 1 0.0153 0.0728 0.6231
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0094 0.0136
Toxoplasma gondii diacylglycerol kinase, putative 0.003 0.0087 0.0311
Schistosoma mansoni DNA polymerase IV / kappa 0.0034 0.0103 0.0296
Echinococcus multilocularis fibropellin Ia 0.0026 0.0062 0.0177
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0023 0.0045 0.0291
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0044 0.0155 0.0445
Echinococcus granulosus cathepsin b 0.0018 0.0021 0.0061
Giardia lamblia GTOR 0.0044 0.0155 0.2647
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.003 0.0087 0.0248
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0023 0.0045 0.013
Loa Loa (eye worm) ACC-1 protein 0.0023 0.0045 0.0291
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0014 0.0039
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0034 0.0107 0.0912
Onchocerca volvulus 0.0026 0.0062 0.0364
Echinococcus granulosus nAChR subunit 0.0023 0.0045 0.013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0122 0.1046
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0191 0.2494
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0156
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0177
Onchocerca volvulus 0.0055 0.0216 0.175
Echinococcus multilocularis neurogenic locus protein delta 0.0026 0.0062 0.0177
Loa Loa (eye worm) hypothetical protein 0.0044 0.0155 0.1005
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0207 0.1009 0.655
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0155 0.2812
Onchocerca volvulus 0.0023 0.0045 0.0216
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0155 0.1343
Loa Loa (eye worm) hypothetical protein 0.0118 0.0544 0.3532
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0118 0.0544 0.0537
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Plasmodium vivax glutathione S-transferase, putative 0.0025 0.006 0.0741
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0413 0.8217
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0036 0.0117 0.017
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Trypanosoma cruzi cysteine peptidase, putative 0.1285 0.6659 1
Brugia malayi calcium ATPase 0.004 0.0137 0.1173
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0026 0.0064 0.0805
Onchocerca volvulus 0.0055 0.0216 0.175
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0044 0.0155 0.0445
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0021 0.0235
Loa Loa (eye worm) ACC-1 protein 0.0023 0.0045 0.0291
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0199 0.3404
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0118 0.0544 0.1966
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0055 0.0216 0.1403
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0111 0.0948
Trypanosoma cruzi DNA polymerase eta, putative 0.0083 0.0363 0.054
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0085 0.0373 0.7374
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0124 0.1068
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0087 0.0384 0.1101
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0045 0.0387
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Onchocerca volvulus 0.0019 0.0027 0.0054
Echinococcus granulosus protein jagged 1 0.0026 0.0062 0.0177
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0021 0.0156
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0233 0.115 0.1552
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0111 0.0398
Loa Loa (eye worm) glutathione reductase 0.0092 0.0409 0.2655
Trichomonas vaginalis Heterochromatin protein, putative 0.0034 0.0107 0.0911
Plasmodium vivax copper-transporting ATPase, putative 0.0026 0.0064 0.0818
Onchocerca volvulus 0.0034 0.0104 0.074
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0094 0.1392
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0026 0.0064 0.0547
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Echinococcus granulosus cysteine protease 0.0039 0.0134 0.0384
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0111 0.0161
Loa Loa (eye worm) Notch2 0.0026 0.0062 0.0399
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0695 0.9204
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0199 0.0294
Echinococcus granulosus protein kinase C gamma type 0.0249 0.123 0.3529
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0085 0.0373 0.3268
Echinococcus multilocularis neurogenic locus protein delta 0.0026 0.0062 0.0177
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1922 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0039 0.0134 0.1734
Onchocerca volvulus 0.003 0.0087 0.0586
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0384 0.1101
Echinococcus multilocularis serine:threonine protein kinase 38 0.0044 0.0155 0.0445
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0216 0.1881
Schistosoma mansoni Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) 0.0025 0.006 0.0172
Entamoeba histolytica hypothetical protein 0.0023 0.0046 0.0516
Toxoplasma gondii EGF family domain-containing protein 0.0026 0.0062 0.0221
Loa Loa (eye worm) hypothetical protein 0.0041 0.0142 0.0918
Onchocerca volvulus Neurogenic locus notch homolog 0.0026 0.0064 0.038
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0191 0.1237
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0528
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0046 0.0471
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0036 0.0117 0.017
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0111 0.0948
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0045 0.0387
Entamoeba histolytica hypothetical protein 0.0109 0.0499 1
Brugia malayi Muscle positioning protein 4 0.0026 0.0062 0.0528
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0155 0.134
Brugia malayi cathepsin L precursor 0.0018 0.0021 0.0181
Brugia malayi hypothetical protein 0.0034 0.0103 0.0879
Trichomonas vaginalis glutaminyl-tRNA synthetase, putative 0.002 0.0029 0.0229
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0056 0.0222 0.0248
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0004 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0107 0.0911
Onchocerca volvulus 0.0083 0.0361 0.3048
Schistosoma mansoni cathepsin C 0.0018 0.0021 0.0061
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Brugia malayi follicle stimulating hormone receptor 0.0232 0.1141 0.9763
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0023 0.0045 0.013
Loa Loa (eye worm) E1-E2 ATPase 0.0053 0.0203 0.1318
Echinococcus multilocularis chromobox protein 1 0.0153 0.0728 0.2089
Onchocerca volvulus 0.0023 0.0045 0.0216
Entamoeba histolytica protein kinase, putative 0.0044 0.0155 0.2805
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0023 0.0045 0.0291
Trypanosoma cruzi cysteine peptidase, putative 0.0147 0.0695 0.1039
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0046 0.0471
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0037 0.012 0.0343
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0528
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0036 0.0117 0.0997
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0026 0.0064 0.0183
Brugia malayi Animal haem peroxidase family protein 0.008 0.0344 0.2946
Brugia malayi Protein cec-1. 0.0034 0.0107 0.0912
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0191 0.1656
Trichomonas vaginalis chromobox protein, putative 0.0097 0.0433 0.3798
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0026 0.0064 0.0534
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0111 0.1427
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.0203 0.2659
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0094 0.0338
Schistosoma mansoni glutathione-S-transferase 0.0025 0.006 0.0172
Leishmania major cathepsin L-like protease 0.0055 0.0216 0.2833
Schistosoma mansoni unc-13 (munc13) 0.0037 0.012 0.0343
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0027 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0174
Onchocerca volvulus Dual oxidase homolog 0.008 0.0344 0.2897
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0063 0.053
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0155 0.0228
Schistosoma mansoni hypothetical protein 0.0109 0.0499 0.143
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0023 0.005 0.0425
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0111 0.0161
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0155 0.134
Leishmania major cysteine peptidase A (CPA) 0.0055 0.0216 0.2833
Echinococcus multilocularis copper transporting ATPase 1 0.0026 0.0064 0.0183
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0135
Schistosoma mansoni hypothetical protein 0.004 0.0134 0.0384
Schistosoma mansoni cell polarity protein 0.0026 0.0062 0.0177
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0111 0.1876
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Brugia malayi calcium ATPase 0.0036 0.0117 0.0997
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0216 0.1881
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0142 0.0407
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0111 0.1876
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Loa Loa (eye worm) hypothetical protein 0.002 0.0029 0.0189
Entamoeba histolytica hypothetical protein 0.0034 0.0107 0.1788
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Schistosoma mansoni chromobox protein 0.0034 0.0107 0.0306
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0134 0.2359
Echinococcus granulosus cpg binding protein 0.0029 0.0081 0.0233
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0061
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0093 0.0413 0.5457
Giardia lamblia Myb 1-like protein 0.0086 0.0375 0.698
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0045 0.013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0216 0.1881
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0093 0.0413 0.1186
Leishmania major copper-transporting ATPase-like protein, putative 0.0026 0.0064 0.0805
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0109 0.0929
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0034 0.0107 0.0306
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0191 0.0282
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0026 0.0064 0.0057
Schistosoma mansoni hypothetical protein 0.004 0.0134 0.0384
Echinococcus multilocularis N chimaerin 0.003 0.0087 0.0248
Loa Loa (eye worm) hypothetical protein 0.0199 0.0969 0.6288
Echinococcus granulosus Diacylglycerol kinase theta 0.003 0.0087 0.0248
Onchocerca volvulus 0.0231 0.1137 1
Schistosoma mansoni hypothetical protein 0.005 0.019 0.0545
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0094 0.0136
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0435 0.1249
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0064 0.0414
Plasmodium vivax glutathione reductase, putative 0.0092 0.0409 0.7416
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0191 0.0548
Loa Loa (eye worm) hypothetical protein 0.0034 0.0107 0.069
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0076 0.0327 0.0937
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Onchocerca volvulus 0.008 0.0344 0.2897
Loa Loa (eye worm) hypothetical protein 0.0066 0.0274 0.1779
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0055 0.0216 0.1403
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0023 0.0045 0.0387
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0528
Entamoeba histolytica hypothetical protein 0.0109 0.0499 1
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0023 0.0045 0.013
Brugia malayi Thioredoxin reductase 0.0092 0.0409 0.3501
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0045 0.013
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0177
Trichomonas vaginalis chromobox protein, putative 0.0153 0.0728 0.6406
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0021 0.0181
Onchocerca volvulus 0.0019 0.0027 0.0054
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0011 0.0031
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0034 0.0107 0.1632
Echinococcus granulosus chromobox protein 2 0.0034 0.0107 0.0306
Schistosoma mansoni laminin gamma-3 chain 0.0026 0.0062 0.0177
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0021 0.0039 0.0254
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0094 0.0269
Loa Loa (eye worm) blistered cuticle protein 3 0.008 0.0344 0.2233
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Echinococcus granulosus tumor protein p63 0.0328 0.1645 0.472
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0021 0.0074
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0021 0.0027
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.035 0.2992
Plasmodium vivax vivapain-2 0.0055 0.0216 0.3731
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0216 0.1881
Schistosoma mansoni nAChR subunit 0.0023 0.0045 0.013
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0111 0.0948
Leishmania major cathepsin L-like protease 0.0055 0.0216 0.2833
Brugia malayi Na,K-ATPase alpha subunit 0.0083 0.0361 0.3091
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0 0.0003
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0118 0.0544 0.0812
Loa Loa (eye worm) hypothetical protein 0.0048 0.0178 0.1156
Schistosoma mansoni diacylglycerol kinase theta 0.003 0.0087 0.0248
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.003 0.0087 0.0248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0097 0.0825
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Schistosoma mansoni hypothetical protein 0.028 0.1392 0.3993
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0412
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0021 0.0181
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.021 0.1027 0.1379
Schistosoma mansoni ATPase 0.0118 0.0544 0.1561
Plasmodium vivax P-type ATPase4, putative 0.0118 0.0544 1
Echinococcus granulosus protein kinase c iota type 0.0074 0.0315 0.0903
Echinococcus multilocularis cathepsin b 0.0018 0.0021 0.0061
Echinococcus granulosus microtubule associated protein 2 0.067 0.3436 0.9858
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0021 0.0156
Onchocerca volvulus 0.0047 0.0172 0.1354
Onchocerca volvulus 0.008 0.0344 0.2897
Trypanosoma cruzi cysteine peptidase, putative 0.0147 0.0695 0.1039
Echinococcus granulosus Ankyrin 0.0014 0.0002 0.0005
Loa Loa (eye worm) animal heme peroxidase 0.008 0.0344 0.2233
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0448 0.1285
Echinococcus granulosus RNA directed DNA polymerase 0.0199 0.0969 0.2779
Plasmodium falciparum cysteine proteinase falcipain 3 0.0055 0.0216 0.3731
Echinococcus multilocularis protein kinase c epsilon type 0.008 0.0348 0.0998
Loa Loa (eye worm) variant SH3 domain-containing protein 0.003 0.0087 0.056
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0022 0.0243
Onchocerca volvulus 0.0023 0.0045 0.0216
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.0529
Schistosoma mansoni rab6-interacting 0.0019 0.0027 0.0078
Toxoplasma gondii thioredoxin reductase 0.0092 0.0409 0.1477
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0046 0.0163
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0413 0.3624
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0023 0.0045 0.013
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0083 0.0361 0.2343
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0004 0.0021
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0103 0.015
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0125 0.0582 0.087
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0199 0.0718
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0107 0.1788
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0011 0.0069
Onchocerca volvulus 0.0048 0.0178 0.141
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0056 0.0222 0.1439
Onchocerca volvulus Slit protein homolog 0.0026 0.0062 0.0364
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0021 0.0135
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0026 0.0064 0.0229
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0104 0.0886
Schistosoma mansoni intermediate filament proteins 0.0026 0.0064 0.0184
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0093 0.0413 0.5457
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Echinococcus granulosus serine:threonine protein kinase N2 0.0044 0.0155 0.0445
Toxoplasma gondii cathepsin B 0.0018 0.0021 0.0074
Echinococcus multilocularis bloom syndrome protein 0.0046 0.0169 0.0486
Loa Loa (eye worm) hypothetical protein 0.003 0.0087 0.056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0097 0.0825
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.035 0.1003
Loa Loa (eye worm) hypothetical protein 0.0119 0.055 0.3569
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0107 0.0911
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0413 0.3624
Schistosoma mansoni nAChR subunit 0.0023 0.0045 0.013
Trypanosoma brucei unspecified product 0.0075 0.0319 0.4195
Echinococcus multilocularis cathepsin L 0.0018 0.0021 0.0061
Brugia malayi hypothetical protein 0.0119 0.055 0.4705
Loa Loa (eye worm) notch protein 0.0026 0.0062 0.0399
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0191 0.0548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0695 0.9204
Loa Loa (eye worm) hypothetical protein 0.0026 0.0064 0.0414
Onchocerca volvulus 0.0055 0.0216 0.175
Trypanosoma cruzi cysteine peptidase, putative 0.0147 0.0695 0.1039
Onchocerca volvulus Huntingtin homolog 0.0119 0.055 0.474
Echinococcus multilocularis slit 2 protein 0.0026 0.0062 0.0177
Brugia malayi RhoGEF domain containing protein 0.003 0.0087 0.0741
Brugia malayi Protein kinase domain containing protein 0.0044 0.0155 0.1327
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0254
Brugia malayi CHD4 protein 0.0036 0.0115 0.0983
Echinococcus granulosus Protein kinase C brain isozyme 0.0279 0.139 0.3987
Echinococcus multilocularis calcium transporting atpase 0.0101 0.0458 0.1313
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0097 0.0825
Onchocerca volvulus 0.0026 0.0064 0.0384
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0066 0.0274 0.0407
Echinococcus granulosus cathepsin L cysteine protease 0.0039 0.0134 0.0384
Schistosoma mansoni phosphoserine phosphatase 0.0017 0.0014 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0135
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0023 0.0045 0.013
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0026 0.0064 0.0547
Trypanosoma brucei DNA polymerase kappa, putative 0.0134 0.063 0.8342
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.008 0.0348 0.2257
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0085 0.0373 0.7374
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0083 0.0363 0.131
Leishmania major P-type ATPase, putative 0.0076 0.0327 0.4302
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0695 0.9204
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0014 0.0039
Echinococcus granulosus dna polymerase kappa 0.0134 0.063 0.1808
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0021 0.0181
Echinococcus granulosus protein jagged 1 0.0026 0.0062 0.0177
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0199 0.3404
Brugia malayi Cation transporter family protein 0.0023 0.0045 0.0387
Brugia malayi E1-E2 ATPase family protein 0.0026 0.0064 0.0547
Onchocerca volvulus 0.0055 0.0216 0.175
Echinococcus multilocularis microtubule associated protein 2 0.067 0.3436 0.9858
Entamoeba histolytica protein kinase, putative 0.0044 0.0155 0.2805
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0135
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0191 0.0688
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0031 0.0091 0.1333
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0023 0.0045 0.0387
Brugia malayi cathepsin F-like cysteine proteinase 0.0021 0.0039 0.0338
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0014 0.0039
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0056 0.008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0061
Schistosoma mansoni nAChR subunit 0.0023 0.0045 0.013
Echinococcus granulosus neural cadherin 0.0026 0.0062 0.0177
Echinococcus granulosus lamin dm0 0.0026 0.0064 0.0184
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0352 0.4641
Brugia malayi hypothetical protein 0.0118 0.0546 0.4671
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0413 0.3624
Brugia malayi Cathepsin L-like precursor 0.0055 0.0216 0.1851
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0155 0.134
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0191 0.1656
Entamoeba histolytica cysteine proteinase 1, putative 0.0039 0.0134 0.2359
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0094 0.0048
Trichomonas vaginalis DNA helicase recq1, putative 0.0046 0.0169 0.1467
Trypanosoma brucei DNA polymerase kappa, putative 0.0115 0.0528 0.6988
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0094 0.0136
Brugia malayi RhoGAP domain containing protein 0.003 0.0087 0.0741
Echinococcus granulosus neuropeptide s receptor 0.0455 0.2311 0.6629
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.004 0.0137 0.0492
Schistosoma mansoni smad1 5 8 and 0.0016 0.0011 0.0031
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0155 0.2812
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0155 0.0446
Loa Loa (eye worm) hypothetical protein 0.005 0.019 0.1232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0412
Brugia malayi Pre-SET motif family protein 0.0203 0.0989 0.8458
Brugia malayi Glutathione S-transferase 4 0.002 0.0029 0.0252
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0103 0.015
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0233 0.115 0.1552
Brugia malayi Cytochrome P450 family protein 0.0015 0.0007 0.0064
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.014 0.2271
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.002 0.0029 0.0174
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0014 0.0047
Schistosoma mansoni DNA helicase recq1 0.0019 0.0027 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0021 0.0156
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0173
Brugia malayi Cathepsin L-like precursor 0.0055 0.0216 0.1851
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0083 0.0361 0.0354
Toxoplasma gondii cathepsin CPC1 0.0018 0.0021 0.0074
Brugia malayi MH1 domain containing protein 0.0016 0.0011 0.0094
Echinococcus granulosus cathepsin b 0.0018 0.0021 0.0061
Loa Loa (eye worm) hypothetical protein 0.0034 0.0107 0.069
Echinococcus granulosus survival motor neuron protein 1 0.023 0.1129 0.324
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0046 0.0169 0.3092
Echinococcus multilocularis serine threonine protein kinase 0.0249 0.123 0.3529
Onchocerca volvulus 0.0023 0.0045 0.0216
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0755 0.4904
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0066 0.0274 0.4993
Schistosoma mansoni rac gtpase activating protein 0.003 0.0087 0.0248
Loa Loa (eye worm) hypothetical protein 0.0026 0.0064 0.0413
Mycobacterium tuberculosis Conserved hypothetical protein 0.0108 0.0495 0.0631
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Trypanosoma cruzi DNA polymerase kappa, putative 0.0134 0.063 0.0941
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0111 0.0948
Echinococcus multilocularis glycine receptor subunit beta 0.0023 0.0045 0.013
Brugia malayi Protein kinase domain containing protein 0.0032 0.0094 0.0802
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0274 0.0787
Trichomonas vaginalis pc-MYB2, putative 0.0085 0.0373 0.3268
Echinococcus granulosus copper transporting ATPase 1 0.0026 0.0064 0.0183
Toxoplasma gondii melibiase subfamily protein 0.0099 0.0448 0.1617
Toxoplasma gondii P-type ATPase4, putative 0.0083 0.0361 0.1304
Schistosoma mansoni smad 0.0016 0.0011 0.0031
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.138 0.716 1
Brugia malayi Cathepsin L-like precursor 0.0055 0.0216 0.1851
Trypanosoma cruzi cruzipain precursor, putative 0.0147 0.0695 0.1039
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0021 0.0181
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0134 0.0384
Plasmodium falciparum heterochromatin protein 1 0.0034 0.0107 0.1632
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0124 0.1068
Echinococcus multilocularis cation transporting ATPase 13A1 0.0026 0.0064 0.0183
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0254
Echinococcus multilocularis notch 0.0026 0.0062 0.0177
Trichomonas vaginalis pc-MYB2, putative 0.0085 0.0373 0.3268
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0045 0.0387
Leishmania major calcium-transporting ATPase, putative 0.0066 0.0274 0.3607
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0014 0.0039
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0094 0.1204
Trichomonas vaginalis C-MYB, putative 0.0085 0.0373 0.3268
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0044 0.0155 0.0445
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0094 0.1204
Trypanosoma brucei calcium-transporting ATPase, putative 0.004 0.0135 0.1753
Onchocerca volvulus 0.0081 0.035 0.2945
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.2007 0.5758
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0199 0.0969 0.2779
Trypanosoma cruzi proton motive ATPase 1, putative 0.0017 0.0014 0.0015
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0042 0.0148 0.1276
Loa Loa (eye worm) raf kinase 0.003 0.0087 0.056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0695 0.9204
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0021 0.0181
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.0203 0.1766
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0082 0.0235
Echinococcus multilocularis glutathione S transferase 0.0025 0.006 0.0172
Echinococcus multilocularis raf serine:threonine protein kinase 0.003 0.0087 0.0248
Schistosoma mansoni hypothetical protein 0.004 0.0134 0.0384
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0064 0.0183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0216 0.1881
Schistosoma mansoni alpha-glucosidase 0.0136 0.064 0.1836
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0122 0.1047
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0428 0.1227
Schistosoma mansoni nAChR subunit 0.0023 0.0045 0.013
Loa Loa (eye worm) hypothetical protein 0.003 0.0087 0.056
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0056 0.0739
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0045 0.0387
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0413
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0046 0.0038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0094 0.0136
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0094 0.1392
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0103 0.015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.014 0.1203
Echinococcus multilocularis Smad4 0.0016 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.0034 0.0104 0.0671
Entamoeba histolytica cysteine proteinase, putative 0.0055 0.0216 0.4088
Echinococcus multilocularis dna polymerase eta 0.0158 0.0755 0.2165
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0076 0.0327 0.0937
Loa Loa (eye worm) hypothetical protein 0.0055 0.0216 0.1403
Brugia malayi Associated with TFs and helicases family protein 0.0034 0.0107 0.0912
Loa Loa (eye worm) hypothetical protein 0.005 0.0187 0.1215
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0044 0.0155 0.1005
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0014 0.0039
Echinococcus multilocularis glutathione s transferase mu 0.0025 0.006 0.0172
Brugia malayi chromobox protein homolog 3 0.0091 0.0402 0.3436
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0118 0.034
Schistosoma mansoni hypothetical protein 0.004 0.0134 0.0384
Onchocerca volvulus 0.0062 0.0254 0.2083
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0017 0.0014 0.0039
Loa Loa (eye worm) hypothetical protein 0.003 0.0087 0.056
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0155 0.0446
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0087 0.0248
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0026 0.0064 0.0026
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0073 0.0471
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0695 0.9204
Leishmania major calcium-translocating P-type ATPase 0.0118 0.0544 0.7199
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0103 0.1327
Echinococcus multilocularis chromobox protein 2 0.0034 0.0107 0.0306
Trypanosoma brucei chrX additional, unordered contigs 0.0034 0.0103 0.1327
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0056 0.0222 0.1899
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0021 0.0156
Loa Loa (eye worm) hypothetical protein 0.008 0.0344 0.2233
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0222 0.193
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0004 0.003
Treponema pallidum cation-transporting ATPase, P-type 0.0026 0.0064 0.005
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0061
Schistosoma mansoni unc-13 (munc13) 0.0037 0.012 0.0343
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0032 0.0094 0.0087
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0103 0.1327
Echinococcus multilocularis musashi 0.0026 0.0064 0.0184
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0094 0.1204
Echinococcus granulosus peroxidasin 0.008 0.0344 0.0988
Brugia malayi diacylglycerol kinase 0.003 0.0087 0.0741
Echinococcus granulosus cathepsin L 0.0018 0.0021 0.0061
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0216 0.1881
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0216 0.1881
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0032 0.0094 0.0607
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0039 0.0134 0.1151
Onchocerca volvulus 0.002 0.0029 0.0074
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0115 0.0528 0.0678
Plasmodium vivax calcium-transporting ATPase, putative 0.0118 0.0544 1
Onchocerca volvulus Peroxidasin homolog 0.008 0.0344 0.2897
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0428 0.3659
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0107 0.0306
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0155 0.0445
Echinococcus multilocularis Ankyrin 0.0014 0.0002 0.0005
Echinococcus multilocularis cysteine protease 0.0055 0.0216 0.0621
Schistosoma mansoni notch 0.0026 0.0062 0.0177
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0428 0.1227
Trichomonas vaginalis cation-transporting ATPase, putative 0.0093 0.0413 0.3624
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0082 0.0235
Onchocerca volvulus 0.0122 0.0564 0.4863
Schistosoma mansoni chromobox protein 0.0034 0.0107 0.0306
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0027 0.0231
Echinococcus multilocularis myotubularin protein 13 0.003 0.0087 0.0248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.008 0.0678
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0026 0.0064 0.0057
Loa Loa (eye worm) animal heme peroxidase 0.008 0.0344 0.2233
Echinococcus granulosus glycine receptor subunit beta 0.0023 0.0045 0.013
Brugia malayi Cathepsin L-like precursor 0.0055 0.0216 0.1851
Brugia malayi SET domain containing protein 0.0036 0.0115 0.0987
Treponema pallidum NADH oxidase 0.0032 0.0094 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0104 0.0886
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0097 0.0825
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0055 0.0216 0.0621
Entamoeba histolytica hypothetical protein 0.0034 0.0107 0.1788
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Trypanosoma cruzi cation-transporting ATPase, putative 0.0026 0.0064 0.0091
Trichomonas vaginalis C-MYB, putative 0.0085 0.0373 0.3268
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0104 0.0298
Leishmania major hypothetical protein, conserved 0.0052 0.0199 0.2605
Loa Loa (eye worm) hypothetical protein 0.0062 0.0254 0.1644
Loa Loa (eye worm) hypothetical protein 0.003 0.0087 0.056
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0085 0.0373 0.3268
Echinococcus multilocularis neurogenic locus notch protein 4 0.0026 0.0062 0.0177
Schistosoma mansoni chromobox protein 0.0153 0.0728 0.2089
Echinococcus multilocularis neuropeptide s receptor 0.0455 0.2311 0.6629
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0021 0.0156
Brugia malayi glutathione transferase 0.0025 0.006 0.0513
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0082 0.0294
Loa Loa (eye worm) RasGEF domain-containing protein 0.003 0.0087 0.056
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0083 0.0361 0.1036
Echinococcus multilocularis Chromobox protein 3 0.0034 0.0107 0.0306
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0177
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0061
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0086 0.0375 0.3287
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0076 0.0327 0.0937
Trypanosoma cruzi cysteine proteinase, putative 0.0039 0.0134 0.0196
Trypanosoma cruzi cysteine proteinase, putative 0.0039 0.0134 0.0196
Echinococcus multilocularis protein dispatched 1 0.0047 0.0172 0.0494
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0021 0.0061
Trypanosoma brucei unspecified product 0.0128 0.0597 0.7895
Plasmodium vivax cation transporting ATPase, putative 0.0026 0.0064 0.0818
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0045 0.013
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0327 0.2857
Echinococcus multilocularis RNA directed DNA polymerase 0.0199 0.0969 0.2779
Schistosoma mansoni lamin 0.0026 0.0064 0.0184
Echinococcus multilocularis glutathione S transferase 0.0025 0.006 0.0172
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0026 0.0064 0.0534
Echinococcus multilocularis Diacylglycerol kinase theta 0.003 0.0087 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Loa Loa (eye worm) MH2 domain-containing protein 0.0235 0.1161 0.7535
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0222 0.193
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0021 0.0156
Loa Loa (eye worm) hypothetical protein 0.0083 0.0361 0.2343
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0083 0.0361 0.7123
Echinococcus granulosus geminin 0.0679 0.3486 1
Trichomonas vaginalis cation-transporting ATPase, putative 0.0026 0.0064 0.0534
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.0642 0.1843
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0082 0.0235
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0155 0.134
Schistosoma mansoni alpha-glucosidase 0.0136 0.064 0.1836
Echinococcus granulosus unc 13 munc13 0.0037 0.012 0.0343
Onchocerca volvulus 0.0026 0.0062 0.0364
Schistosoma mansoni transcription factor LCR-F1 0.0109 0.0499 0.143
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0034 0.0107 0.1632
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0046 0.0563
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0209 0.0754
Brugia malayi Cadherin domain containing protein 0.0026 0.0062 0.0528
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0045 0.013
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0064 0.0548
Echinococcus granulosus slit 2 protein 0.0026 0.0062 0.0177
Brugia malayi hypothetical protein 0.008 0.0344 0.2946
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0027 0.0077
Schistosoma mansoni vav2 0.003 0.0087 0.0248
Brugia malayi MAP kinase sur-1 0.005 0.0191 0.1633
Loa Loa (eye worm) AGC/AKT protein kinase 0.0044 0.0155 0.1005
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0099 0.0448 0.1285
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0402 0.3518
Leishmania major P-type H -ATPase, putative 0.0053 0.0203 0.2659
Onchocerca volvulus Cathepsin L homolog 0.0055 0.0216 0.175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0155 0.1343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0039 0.0134 0.1734
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0695 0.9204
Brugia malayi CHE-14 protein 0.0041 0.0142 0.1213
Loa Loa (eye worm) RecQ helicase 0.0046 0.0169 0.1098
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0155 0.1007
Schistosoma mansoni hypothetical protein 0.0679 0.3486 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0055 0.0216 0.1881
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0695 0.9204
Echinococcus granulosus fibropellin Ia 0.0026 0.0062 0.0177
Echinococcus granulosus protein kinase c eta type 0.003 0.0087 0.0248
Loa Loa (eye worm) hypothetical protein 0.0081 0.035 0.2269
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0085 0.0373 0.3268
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0021 0.0156
Loa Loa (eye worm) hypothetical protein 0.0308 0.154 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0262 0.075
Giardia lamblia NADH oxidase lateral transfer candidate 0.0032 0.0094 0.1436
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0094 0.027
Toxoplasma gondii cathepsin CPC2 0.0018 0.0021 0.0074
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0101 0.0458 0.1313
Brugia malayi Cation transporter family protein 0.0023 0.0045 0.0387
Loa Loa (eye worm) hypothetical protein 0.003 0.0087 0.056
Toxoplasma gondii AGC kinase 0.0044 0.0155 0.0558
Schistosoma mansoni notch 0.0026 0.0062 0.0177
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0695 0.9204
Entamoeba histolytica diacylglycerol kinase, putative 0.003 0.0087 0.137
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0011 0.0069
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0413 0.3624
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.021 0.1027 0.1379
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0094 0.0136
Onchocerca volvulus Cathepsin F homolog 0.0055 0.0216 0.175
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0155 0.0445
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0413 0.3624
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0027 0.0174
Echinococcus granulosus X box binding protein 1 0.028 0.1392 0.3993
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Brugia malayi Cathepsin L-like precursor 0.0034 0.0104 0.0888
Schistosoma mansoni Smad4 0.0016 0.0011 0.0031
Echinococcus multilocularis protein jagged 1 0.0026 0.0062 0.0177
Leishmania major cathepsin L-like protease 0.0147 0.0695 0.9204
Schistosoma mansoni type V p-type atpase isoform 0.0026 0.0064 0.0183
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0.0014 0.0047
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Schistosoma mansoni protein kinase C 0.0037 0.012 0.0343
Leishmania major DNA polymerase kappa, putative 0.0115 0.0528 0.6988
Echinococcus multilocularis serine:threonine protein kinase N2 0.0044 0.0155 0.0445
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0208 0.0596
Echinococcus multilocularis RUN 0.0019 0.0027 0.0078
Echinococcus granulosus Na:K ATPase alpha subunit 0.0066 0.0274 0.0787
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0216 0.1881
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0107 0.1788
Onchocerca volvulus 0.0064 0.0262 0.2155
Echinococcus multilocularis geminin 0.0679 0.3486 1
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0061
Schistosoma mansoni protein kinase C mu 0.0032 0.0094 0.0269
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0021 0.0027
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0155 0.0228
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0111 0.0717
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0044 0.0155 0.0445
Brugia malayi Protein kinase domain containing protein 0.0044 0.0155 0.1327
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0021 0.0235
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.014 0.1203
Trypanosoma brucei DNA polymerase IV, putative 0.0128 0.0597 0.7895
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0044 0.0155 0.0445
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0023 0.005 0.0425
Plasmodium falciparum DNA repair protein REV1, putative 0.0034 0.0103 0.1568
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.0642 0.1843
Echinococcus granulosus cathepsin L cysteine proteinase 0.0055 0.0216 0.0621
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0155 0.0445
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0026 0.0064 0.0057
Echinococcus multilocularis glutathione S transferase 0.002 0.0029 0.0085
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0384 0.1101
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0094 0.0136
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0021 0.0156
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0039 0.0134 0.0196
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.003 0.0087 0.0248
Echinococcus multilocularis glycine receptor subunit beta 0.0023 0.0045 0.013
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0155 0.133
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0064 0.0414
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0061
Echinococcus multilocularis protein kinase c iota type 0.0074 0.0315 0.0903
Plasmodium vivax DNA repair protein REV1, putative 0.0034 0.0103 0.1568
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0118 0.0544 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0004 0.001
Plasmodium vivax SET domain protein, putative 0.003 0.0082 0.1161
Loa Loa (eye worm) AGC/PKN protein kinase 0.0044 0.0155 0.1005
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0448 0.1285
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0094 0.1204
Loa Loa (eye worm) hypothetical protein 0.003 0.0087 0.056
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0062 0.0177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0413
Brugia malayi Animal haem peroxidase family protein 0.008 0.0344 0.2946
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0007 0.0046
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0107 0.0383
Echinococcus granulosus raf serine:threonine protein kinase 0.003 0.0087 0.0248
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0055 0.0216 0.3731
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0093 0.0413 0.7733
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0448 0.1285
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0199 0.2605
Echinococcus granulosus protein jagged 2 0.0026 0.0062 0.0177
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0092 0.0409 0.0511
Schistosoma mansoni notch 0.0026 0.0062 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0107 0.0911
Echinococcus granulosus N chimaerin 0.003 0.0087 0.0248
Echinococcus granulosus glutathione S transferase 0.0025 0.006 0.0172
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0023 0.0045 0.0291
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0023 0.0045 0.013
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0191 0.0548
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0062 0.0177
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0035 0.011 0.009
Loa Loa (eye worm) hypothetical protein 0.0037 0.012 0.0775
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0026 0.0064 0.0026
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0242 0.0695
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0111 0.0318
Schistosoma mansoni DNA polymerase eta 0.0158 0.0755 0.2165
Trypanosoma brucei cation-transporting ATPase, putative 0.0026 0.0064 0.0805
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0045 0.0387
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0254
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0155 0.134
Onchocerca volvulus Putative cubilin 0.0026 0.0062 0.0364
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0026 0.0064 0.0183
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0177
Loa Loa (eye worm) hypothetical protein 0.0091 0.0402 0.2605
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0199 0.3404
Entamoeba histolytica cysteine protease, putative 0.0039 0.0134 0.2359
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0023 0.0045 0.013
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0109 0.0499 0.143
Echinococcus granulosus protein jagged 2 0.0026 0.0062 0.0177
Loa Loa (eye worm) hypothetical protein 0.0145 0.0688 0.4466
Echinococcus multilocularis cathepsin L cysteine protease 0.0055 0.0216 0.0621
Schistosoma mansoni cation-transporting ATPase 0.0026 0.0064 0.0183
Plasmodium falciparum thioredoxin reductase 0.0092 0.0409 0.7416
Brugia malayi Delta serrate ligand family protein 0.0026 0.0062 0.0528
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0107 0.0911
Schistosoma mansoni copper ABC transporter ATPase 0.0026 0.0064 0.0183
Brugia malayi Melibiase family protein 0.0066 0.0274 0.2347
Brugia malayi cathepsin L-like precursor 0.0034 0.0104 0.0888
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0291
Plasmodium vivax vivapain-2 0.0055 0.0216 0.3731
Schistosoma mansoni diacylglycerol kinase theta 0.003 0.0087 0.0248
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0111 0.0948
Schistosoma mansoni alpha glucosidase 0.0035 0.0111 0.0318
Brugia malayi Hr1 repeat family protein 0.0044 0.0155 0.1327
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0032 0.0094 0.0802
Brugia malayi ImpB/MucB/SamB family protein 0.0108 0.0495 0.4235
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0026 0.0064 0.0534
Schistosoma mansoni lipoxygenase 0.0019 0.0027 0.0078
Trypanosoma cruzi DNA polymerase kappa, putative 0.0134 0.063 0.0941
Entamoeba histolytica deoxycytidyl transferase, putative 0.0108 0.0495 0.9923
Brugia malayi excitatory GABA receptor EXP-1A 0.0023 0.0045 0.0387
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0026 0.0064 0.0026
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0155 0.2022
Echinococcus multilocularis neural cadherin 0.0026 0.0062 0.0177
Schistosoma mansoni hypothetical protein 0.0034 0.0107 0.0306
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0061
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0094 0.0804
Schistosoma mansoni hypothetical protein 0.0023 0.0049 0.0141
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0135
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0024 0.0054 0.0156
Mycobacterium tuberculosis Probable oxidoreductase 0.0233 0.115 0.1552
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.006 0.0387
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0155 0.2022
Brugia malayi GCC2 and GCC3 family protein 0.0026 0.0062 0.0528
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0097 0.0433 0.3694
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0107 0.0911
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0755 0.2167
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0107 0.0911
Loa Loa (eye worm) AGC/NDR protein kinase 0.0044 0.0155 0.1005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0399
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0094 0.08
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0023 0.0045 0.0387
Brugia malayi polk-prov protein 0.0059 0.0238 0.204
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0061

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) ~ 1 mg kg-1 In vivo inhibitory activity against metrazole-induced seizures in mice by intraperitoneal administration ChEMBL. 10386933
ED50 (functional) ~ 1 mg kg-1 In vivo inhibitory activity against metrazole-induced seizures in mice by intraperitoneal administration ChEMBL. 10386933
ED50 (functional) > 10 mg kg-1 In vivo inhibitory activity against metrazole-induced seizures in mice by peroral administration ChEMBL. 10386933
ED50 (functional) > 10 mg kg-1 In vivo inhibitory activity against metrazole-induced seizures in mice by peroral administration ChEMBL. 10386933
GS (binding) = 2.8 GABA shift which is the ratio of binding in the absence and presence of GABA (1 mM) was determined ChEMBL. 10386933
GS (binding) = 2.8 GABA shift which is the ratio of binding in the absence and presence of GABA (1 mM) was determined ChEMBL. 10386933
IC50 (binding) = 10.1 nM In vitro inhibitory against Gamma-aminobutyric-acid A receptor from rat cerebral cortex using [3H]-flunitrazepam as the radioligand ChEMBL. 10386933
IC50 (binding) = 10.1 nM In vitro inhibitory against Gamma-aminobutyric-acid A receptor from rat cerebral cortex using [3H]-flunitrazepam as the radioligand ChEMBL. 10386933
MED (functional) > 10 mg kg-1 Inhibition of experimentally-induced conflict in rats following i.p. administration. ChEMBL. 10386933
MED (functional) = 30 mg kg-1 Inhibitory activity determined by experimentally-induced conflict test in rats after oral administration ChEMBL. 10386933

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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