Detailed information for compound 560761

Basic information

Technical information
  • TDR Targets ID: 560761
  • Name: 7,8-dimethyl-4-oxo-10-(2,3,4,5-tetrahydroxype ntyl)benzo[g]pteridin-2-olate
  • MW: 375.356 | Formula: C17H19N4O6-
  • H donors: 4 H acceptors: 6 LogP: -0.32 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC(C(C(Cn1c2cc(C)c(cc2nc2c1nc([O-])nc2=O)C)O)O)O
  • InChi: 1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/p-1
  • InChiKey: AUNGANRZJHBGPY-UHFFFAOYSA-M  

Network

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Synonyms

  • 7,8-dimethyl-4-oxo-10-(2,3,4,5-tetrahydroxypentyl)-2-benzo[g]pteridinolate
  • 4-keto-7,8-dimethyl-10-(2,3,4,5-tetrahydroxypentyl)benzo[g]pteridin-2-olate
  • flavin semiquinone
  • Riboflavin
  • 35919-91-6
  • Riboflavin, radical ion(1-)
  • Fad semiquinone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) intermediate filament protein 0.0051 0.0315 0.0372
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0039 0.0213 0.0263
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0045 0.0262 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0146 0.018
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0138 0.0159
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0028 0.0115 0.0117
Echinococcus multilocularis carboxylesterase 5A 0.0158 0.1216 0.1212
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.0122
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0215 0.026
Schistosoma mansoni coup transcription factor 0.004 0.0215 0.0211
Echinococcus multilocularis G protein coupled receptor 139 0.0045 0.0262 0.0257
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Trypanosoma brucei heat shock protein, putative 0.0039 0.0213 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.1028 0.1271
Chlamydia trachomatis acyltransferase family protein 0.0067 0.0443 0.1048
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0128 0.0961 0.1149
Loa Loa (eye worm) hypothetical protein 0.0069 0.0462 0.0549
Onchocerca volvulus 0.0045 0.0262 0.0317
Trichomonas vaginalis glutathione reductase, putative 0.0481 0.395 0.4882
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0052
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0025 0.0091 0.0066
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.003 0.003
Schistosoma mansoni transient receptor potential channel 0.0015 0.0006 0.0001
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0055 0.0346 0.0378
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0136 0.1028 0.1271
Trypanosoma brucei DNA topoisomerase ii 0.0846 0.703 0.8441
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0083 0.0586 0.0698
Toxoplasma gondii phospholipase/carboxylesterase 0.0067 0.0443 0.0527
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0602 0.4969 0.5959
Trichomonas vaginalis endoplasmin, putative 0.0039 0.0213 0.0263
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0128 0.0961 0.1473
Echinococcus multilocularis transient receptor potential cation channel 0.0015 0.0006 0.0001
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0067 0.0443 0.0527
Mycobacterium ulcerans DNA gyrase subunit A 0.0162 0.1251 0.1925
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0075 0.007
Plasmodium vivax hypothetical protein, conserved 0.0067 0.0443 0.0495
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0018 0.0033 0.0028
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0136 0.1028 0.1229
Brugia malayi hypothetical protein 0.0027 0.0107 0.0122
Giardia lamblia NADH oxidase lateral transfer candidate 0.0481 0.395 0.6647
Leishmania major hypothetical protein, conserved 0.0029 0.0129 0.015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0045 0.0262 0.0257
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0067 0.0443 0.0548
Treponema pallidum quinoline 2-oxidoreductase 0.0064 0.0423 0.0698
Echinococcus granulosus abhydrolase domain containing protein 13 0.0067 0.0443 0.0439
Schistosoma mansoni glutamate synthase 0.0128 0.0961 0.0957
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0034 0.0168 0.0196
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0018 0.0033 0.0028
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0128 0.0961 0.1558
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0262 0.0257
Trypanosoma cruzi metacaspase 5, putative 0.0136 0.1028 0.1229
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0151 0.116 0.1156
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0042 0.0234 0.0275
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0128 0.0961 0.1149
Loa Loa (eye worm) hypothetical protein 0.0152 0.1163 0.1392
Onchocerca volvulus 0.0045 0.0262 0.0317
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0481 0.395 0.474
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0033
Entamoeba histolytica 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0116 0.0865 0.1252
Echinococcus granulosus heat shock protein 0.0039 0.0213 0.0208
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0052 0.0324 0.0319
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0037 0.0038
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0045 0.0262 0.0317
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0215 0.0253
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0115 0.0152
Brugia malayi hypothetical protein 0.0142 0.108 0.1292
Brugia malayi jmjC domain containing protein 0.0114 0.0846 0.1011
Brugia malayi DNA topoisomerase III 0.0041 0.0225 0.0264
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.0514 0.0509
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0021 0.0062 0.0069
Schistosoma mansoni ap endonuclease 0.0055 0.0346 0.0342
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0045 0.0262 0.0257
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0029 0.0125 0.0168
Brugia malayi ImpB/MucB/SamB family protein 0.0069 0.0465 0.0552
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase-like 0.0019 0.0042 0.0045
Schistosoma mansoni BC026374 protein (S09 family) 0.0027 0.0107 0.0102
Brugia malayi hypothetical protein 0.0045 0.0262 0.0308
Toxoplasma gondii DNA topoisomerase family protein 0.0041 0.0225 0.0264
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0128 0.0961 0.2255
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0128 0.0961 0.1136
Giardia lamblia DINP protein human, muc B family 0.0082 0.0571 0.0893
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Brugia malayi hypothetical protein 0.0019 0.0039 0.0041
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0027 0.0107 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.049 0.0582
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Echinococcus multilocularis Ankyrin 0.0017 0.0024 0.0019
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0029 0.0125 0.0168
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0128 0.0961 0.0957
Schistosoma mansoni cpg binding protein 0.0084 0.0592 0.0587
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0052 0.0324 0.0383
Trypanosoma brucei developmentally regulated phosphoprotein 0.0039 0.0213 0.025
Echinococcus granulosus neuropeptide receptor 0.0045 0.0262 0.0257
Schistosoma mansoni hypothetical protein 0.0023 0.0075 0.007
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0774 0.6426 0.7943
Echinococcus multilocularis 0.0029 0.0125 0.012
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0039 0.0213 0.0208
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0041 0.0225 0.0264
Schistosoma mansoni voltage-gated cation channel 0.0142 0.108 0.1076
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0056 0.0028
Plasmodium falciparum lysophospholipase, putative 0.0774 0.6426 0.7707
Schistosoma mansoni sodium-dependent amino acid transporter 0.0018 0.0033 0.0028
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0262 0.0257
Schistosoma mansoni ferritin light chain 0.0025 0.0091 0.0086
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0046 0.005
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0029 0.0125 0.0168
Echinococcus granulosus tachykinin peptides receptor 99D 0.0045 0.0262 0.0257
Echinococcus granulosus geminin 0.0322 0.2604 0.2601
Loa Loa (eye worm) hypothetical protein 0.004 0.0215 0.0253
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0029 0.0125 0.0129
Onchocerca volvulus 0.0045 0.0262 0.0317
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0123 0.092 0.0916
Chlamydia trachomatis thioredoxin reductase 0.0128 0.0961 0.237
Schistosoma mansoni sulfide quinone reductase 0.0128 0.0961 0.0957
Plasmodium falciparum esterase, putative 0.0793 0.6586 0.7901
Entamoeba histolytica hypothetical protein 0.0067 0.0443 0.0607
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0128 0.0961 0.0957
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0067 0.0443 0.0548
Brugia malayi Globin family protein 0.0016 0.0017 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.0122
Echinococcus multilocularis folate receptor beta 0.0119 0.0889 0.0885
Plasmodium falciparum JmjC domain-containing protein, putative 0.003 0.0139 0.0127
Echinococcus granulosus Phospholipase carboxylesterase 0.0067 0.0443 0.0439
Loa Loa (eye worm) hypothetical protein 0.0142 0.108 0.1292
Plasmodium vivax lysophospholipase, putative 0.0067 0.0443 0.0495
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0215 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0443 0.0548
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0892 0.1066
Echinococcus granulosus g protein coupled receptor 0.0045 0.0262 0.0257
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.1089 0.1084
Onchocerca volvulus 0.0027 0.0107 0.0126
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0018 0.0033 0.0028
Trypanosoma brucei heat shock protein, putative 0.0039 0.0213 0.025
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0045 0.0262 0.0257
Plasmodium vivax PST-A protein 0.0067 0.0443 0.0495
Loa Loa (eye worm) hypothetical protein 0.0023 0.0075 0.0085
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0049 0.0049
Brugia malayi Dopamine receptor protein 1 0.0045 0.0262 0.0308
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0128 0.0961 0.1473
Mycobacterium ulcerans hypothetical protein 0.0067 0.0443 0.0665
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0019 0.0042 0.0045
Brugia malayi Cytochrome P450 family protein 0.0029 0.0125 0.0144
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0045 0.0262 0.0257
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0033 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0443 0.0548
Onchocerca volvulus 0.0045 0.0262 0.0317
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0041 0.0225 0.0278
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Echinococcus multilocularis JmjC domain containing protein 4 0.003 0.0139 0.0134
Echinococcus multilocularis calcium activated potassium channel 0.0015 0.0009 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0029 0.0125 0.0129
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Schistosoma mansoni hypothetical protein 0.0322 0.2604 0.2601
Plasmodium falciparum lysophospholipase, putative 0.0067 0.0443 0.0495
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0018
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0045 0.0262 0.0257
Echinococcus multilocularis short transient receptor potential channel 6 0.0015 0.0006 0.0001
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0128 0.0961 0.1149
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0215 0.0253
Trichomonas vaginalis sensor histidine kinase, putative 0.0039 0.0213 0.0263
Mycobacterium ulcerans hypothetical protein 0.0021 0.0062 0.007
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0189 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0042 0.0052
Leishmania major hypothetical protein, conserved 0.0128 0.0961 0.1149
Trypanosoma brucei metacaspase 5, putative 0.0136 0.1028 0.1229
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0215 0.026
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0189 0.0221
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0999 0.8328 1
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0774 0.6426 0.9754
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0359 0.2913 0.2909
Toxoplasma gondii phospholipase 0.0067 0.0443 0.0527
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0037 0.0032
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0213 0.0263
Plasmodium falciparum DNA topoisomerase 2 0.0754 0.6251 0.7496
Onchocerca volvulus 0.0051 0.0315 0.0383
Echinococcus granulosus caspase 2 0.0262 0.2096 0.2092
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0047 0.0276 0.0325
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0018 0.0033 0.0028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.0122
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0215 0.0211
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0215 0.0211
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0029 0.0125 0.0168
Echinococcus granulosus g-protein coupled receptor 0.0045 0.0262 0.0257
Loa Loa (eye worm) hypothetical protein 0.0124 0.0929 0.111
Echinococcus multilocularis flap endonuclease 1 0.003 0.0138 0.0133
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0754 0.6251 0.6249
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0046 0.0041
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0075 0.007
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0029 0.0125 0.0168
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0151 0.116 0.1434
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Plasmodium falciparum endoplasmin, putative 0.0039 0.0213 0.0217
Mycobacterium ulcerans DNA topoisomerase I 0.0041 0.0225 0.0324
Schistosoma mansoni lipoxygenase 0.0096 0.0693 0.0689
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0052 0.0324 0.0319
Schistosoma mansoni transient receptor potential channel 0.0015 0.0005 0.000000051483
Schistosoma mansoni jumonji domain containing protein 0.003 0.0139 0.0134
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Brugia malayi Intermediate filament tail domain containing protein 0.0051 0.0315 0.0372
Echinococcus granulosus transient receptor potential cation channel 0.0015 0.0005 0.000000051483
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0086 0.0607 0.0602
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0236 0.0292
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0025 0.0091 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.003 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.021 0.026
Brugia malayi hypothetical protein 0.0019 0.0039 0.0041
Schistosoma mansoni hypothetical protein 0.0045 0.0262 0.0257
Mycobacterium ulcerans aldehyde dehydrogenase 0.0056 0.0351 0.0521
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0111 0.0822 0.0982
Trypanosoma cruzi DNA topoisomerase III, putative 0.0041 0.0225 0.0264
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0045 0.0262 0.0257
Echinococcus multilocularis serotonin receptor 0.0045 0.0262 0.0257
Onchocerca volvulus 0.0126 0.0949 0.1168
Onchocerca volvulus 0.0152 0.1163 0.1432
Trypanosoma cruzi DNA damage repair protein, putative 0.0021 0.0062 0.0069
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0262 0.0257
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0136 0.1034 0.1586
Echinococcus granulosus g protein coupled receptor 0.0045 0.0262 0.0257
Echinococcus granulosus acetylcholinesterase 0.0158 0.1216 0.1212
Schistosoma mansoni netrin receptor unc5 0.0017 0.0023 0.0018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0215 0.0253
Plasmodium vivax metacaspase 1, putative 0.0136 0.1028 0.12
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0029 0.0125 0.0168
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0124 0.0929 0.0925
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0067 0.0443 0.0527
Plasmodium vivax unspecified product 0.0067 0.0443 0.0495
Schistosoma mansoni hypothetical protein 0.0124 0.093 0.0925
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.4849 0.5995
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.0514 0.0509
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0213 0.0263
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0115 0.0103
Schistosoma mansoni neuropeptide receptor 0.0045 0.0262 0.0257
Trypanosoma brucei DNA topoisomerase III, putative 0.0041 0.0225 0.0264
Loa Loa (eye worm) independent phosphoglycerate mutase isoform 2 0.0116 0.0865 0.1033
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.0213 0.0284
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Loa Loa (eye worm) acetylcholinesterase 1 0.0158 0.1216 0.1456
Echinococcus granulosus RUN 0.0023 0.0075 0.007
Brugia malayi hypothetical protein 0.0075 0.0514 0.0612
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0128 0.0961 0.0957
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0056 0.0351 0.0346
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Plasmodium vivax DNA gyrase subunit B, putative 0.0439 0.3595 0.4295
Echinococcus multilocularis serotonin receptor 0.0045 0.0262 0.0257
Schistosoma mansoni terminal deoxycytidyl transferase 0.0069 0.0465 0.046
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0215 0.0253
Trypanosoma cruzi hypothetical protein, conserved 0.0128 0.0961 0.1149
Echinococcus granulosus g protein coupled receptor 0.0045 0.0262 0.0257
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0123 0.092 0.0916
Trichomonas vaginalis conserved hypothetical protein 0.0151 0.116 0.1434
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0039 0.0034
Echinococcus multilocularis neuropeptide Y receptor 0.0045 0.0262 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0215 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0324 0.04
Echinococcus multilocularis serotonin transporter 0.0106 0.0774 0.077
Echinococcus multilocularis sex peptide receptor 0.0045 0.0262 0.0257
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0404 0.3294 0.4072
Plasmodium vivax glutathione reductase, putative 0.0999 0.8328 1
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0128 0.0961 0.1473
Echinococcus multilocularis sodium and chloride dependent glycine 0.0018 0.0033 0.0028
Schistosoma mansoni opsin-like receptor 0.0045 0.0262 0.0257
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0045 0.0262 0.0308
Giardia lamblia Glutamate synthase 0.0128 0.0961 0.1558
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0029 0.0125 0.0129
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0039 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.1028 0.1271
Loa Loa (eye worm) hypothetical protein 0.0028 0.0115 0.0132
Echinococcus multilocularis abhydrolase domain containing 3 0.0067 0.0443 0.0439
Brugia malayi heat shock protein 90 0.0039 0.0213 0.025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0215 0.0253
Loa Loa (eye worm) neuropeptide F receptor 0.0045 0.0262 0.0308
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0046 0.0041
Echinococcus multilocularis dnaJ subfamily B 0.1197 1 1
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0077 0.0533 0.0804
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0055 0.0346 0.041
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0481 0.395 0.474
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0063
Onchocerca volvulus 0.0971 0.8091 1
Plasmodium vivax endoplasmin, putative 0.0039 0.0213 0.0217
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.0122
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.052 0.0604
Schistosoma mansoni caspase-7 (C14 family) 0.0359 0.2913 0.2909
Brugia malayi hypothetical protein 0.0021 0.0058 0.0063
Plasmodium vivax PST-A protein 0.0067 0.0443 0.0495
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.021 0.026
Echinococcus granulosus jumonji domain containing 1A 0.003 0.0139 0.0134
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0139 0.016
Trypanosoma cruzi metacaspase, putative 0.0136 0.1028 0.1229
Plasmodium falciparum thioredoxin reductase 0.0999 0.8328 1
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0029 0.0125 0.0129
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0039 0.0213 0.0235
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0027 0.0113 0.013
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0215 0.0211
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0085 0.0603 0.0719
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0142 0.108 0.1076
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0481 0.395 0.474
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0128 0.0961 0.1136
Loa Loa (eye worm) hypothetical protein 0.0527 0.434 0.5208
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0443 0.0548
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0114 0.0846 0.0842
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0019 0.0046 0.0041
Brugia malayi hypothetical protein 0.0023 0.0075 0.0085
Echinococcus granulosus thioredoxin glutathione reductase 0.0999 0.8328 0.8327
Giardia lamblia Cgi67 serine protease precursor-like protein 0.0067 0.0443 0.0676
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.0887 0.1059
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0056 0.0351 0.0416
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0215 0.0211
Schistosoma mansoni hypothetical protein 0.1197 1 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0443 0.0527
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0276 0.0341
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0045 0.0262 0.0257
Brugia malayi cytochrome P450 0.0029 0.0125 0.0144
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0029 0.0125 0.0129
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0138 0.0159
Toxoplasma gondii aldehyde dehydrogenase 0.0056 0.0351 0.0416
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0128 0.0961 0.143
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0129 0.015
Echinococcus granulosus BC026374 protein S09 family 0.0027 0.0107 0.0102
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0023 0.0074 0.0069
Echinococcus multilocularis G-protein coupled receptor, putative 0.0045 0.0262 0.0257
Leishmania major hypothetical protein, conserved 0.0067 0.0443 0.0527
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0262 0.0257
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0929 0.0925
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0039 0.0041
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0128 0.0961 0.1399
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0439 0.3595 0.4305
Loa Loa (eye worm) hypothetical protein 0.0076 0.052 0.0618
Leishmania major DNA polymerase eta, putative 0.0069 0.0465 0.0552
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0029 0.0125 0.0168
Brugia malayi hypothetical protein 0.0029 0.0129 0.015
Echinococcus granulosus transient receptor potential cation channel 0.0015 0.0005 0.000000051483
Schistosoma mansoni amine GPCR 0.0624 0.5155 0.5153
Loa Loa (eye worm) hypothetical protein 0.0158 0.1216 0.1456
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0037 0.0032
Trypanosoma brucei NADH dehydrogenase 0.0128 0.0961 0.1149
Brugia malayi Dopamine receptor 0.0045 0.0262 0.0308
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0052
Echinococcus multilocularis ubiquitin specific protease 41 0.0151 0.116 0.1156
Schistosoma mansoni caspase-3 (C14 family) 0.0359 0.2913 0.2909
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0588 0.4849 0.7344
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0142 0.108 0.1076
Toxoplasma gondii selenide, water dikinase 0.0128 0.0961 0.1149
Loa Loa (eye worm) hypothetical protein 0.0021 0.0056 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0233 0.0288
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Echinococcus multilocularis voltage gated potassium channel 0.0023 0.0074 0.0069
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0069 0.0465 0.046
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0056 0.0028
Plasmodium falciparum DNA topoisomerase 3, putative 0.0041 0.0225 0.0232
Schistosoma mansoni DNA polymerase eta 0.0069 0.0465 0.046
Loa Loa (eye worm) DNA topoisomerase III 0.0041 0.0225 0.0264
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0039 0.0213 0.0263
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0151 0.116 0.1434
Plasmodium falciparum lysophospholipase, putative 0.0774 0.6426 0.7707
Trypanosoma cruzi metacaspase 5, putative 0.0136 0.1028 0.1229
Mycobacterium ulcerans hypothetical protein 0.0774 0.6426 1
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0062 0.0069
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0892 0.1066
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0142 0.108 0.1076
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0039 0.0034
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0046 0.005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0481 0.395 0.474
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0045 0.0262 0.0308
Schistosoma mansoni sodium/chloride dependent transporter 0.0018 0.0033 0.0028
Onchocerca volvulus 0.0045 0.0262 0.0317
Echinococcus multilocularis BC026374 protein (S09 family) 0.0027 0.0107 0.0102
Echinococcus multilocularis orexin receptor type 2 0.0045 0.0262 0.0257
Schistosoma mansoni hypothetical protein 0.0029 0.0125 0.012
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Loa Loa (eye worm) CYP4Cod1 0.0056 0.0352 0.0417
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.003 0.0037
Mycobacterium leprae Probable two component sensor kinase MprB 0.0039 0.0213 0.0257
Mycobacterium ulcerans dehydrogenase 0.0128 0.0961 0.1473
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0063
Brugia malayi MAP kinase sur-1 0.0047 0.0276 0.0325
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0039 0.0213 0.0305
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0046 0.0041
Leishmania major monoglyceride lipase, putative 0.0774 0.6426 0.7715
Toxoplasma gondii transporter, cation channel family protein 0.0083 0.0586 0.0698
Echinococcus granulosus neuropeptide Y receptor 0.0045 0.0262 0.0257
Schistosoma mansoni pyruvate dehydrogenase 0.0039 0.0213 0.0208
Brugia malayi bHLH-PAS transcription factor 0.0033 0.016 0.0186
Giardia lamblia Fructose-bisphosphate aldolase 0.0588 0.4849 0.8179
Leishmania major cytochrome p450-like protein 0.0029 0.0125 0.0144
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.0122
Loa Loa (eye worm) melatonin receptor type 1A 0.0045 0.0262 0.0308
Echinococcus granulosus lysine specific demethylase 6a 0.003 0.0139 0.0134
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0029 0.0125 0.0129
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0128 0.0961 0.1149
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0051 0.0311 0.071
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0093
Mycobacterium ulcerans hypothetical protein 0.0067 0.0443 0.0665
Schistosoma mansoni neuropeptide F-like receptor 0.0045 0.0262 0.0257
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0039 0.0213 0.0208
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0123 0.092 0.1409
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0041 0.0225 0.022
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0033 0.0028
Trypanosoma brucei DNA topoisomerase IA, putative 0.0041 0.0225 0.0264
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Brugia malayi Carboxylesterase family protein 0.0027 0.0107 0.0122
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0045 0.0262 0.0257
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0041 0.0225 0.022
Schistosoma mansoni phosphatidylserine receptor 0.003 0.0139 0.0134
Trypanosoma cruzi metacaspase, putative 0.0136 0.1028 0.1229
Echinococcus granulosus caspase 3 0.0223 0.1766 0.1762
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0096 0.0091
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0033
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0774 0.6426 0.7943
Brugia malayi PAS domain containing protein 0.0045 0.0258 0.0304
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0236 0.0231
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0045 0.0262 0.0257
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0892 0.1066
Loa Loa (eye worm) hypothetical protein 0.0104 0.0757 0.0903
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0046 0.0049
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0215 0.0253
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Loa Loa (eye worm) hypothetical protein 0.005 0.0307 0.0362
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0262 0.0257
Schistosoma mansoni acetylcholinesterase 0.0027 0.0107 0.0102
Onchocerca volvulus 0.0018 0.0033 0.0034
Mycobacterium ulcerans endonuclease IV 0.0076 0.052 0.0784
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.003 0.0037
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.052 0.0587
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0063
Toxoplasma gondii histone lysine demethylase JMJD6a 0.003 0.0139 0.016
Brugia malayi steroid hormone receptor 0.004 0.0215 0.0253
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0248 0.1981 0.2362
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0062 0.0069
Treponema pallidum NADH oxidase 0.0481 0.395 0.8109
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0128 0.0961 0.1119
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0033 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.021 0.026
Echinococcus granulosus monoacylglycerol lipase abhd12 0.0067 0.0443 0.0439
Mycobacterium ulcerans putative regulatory protein 0.0033 0.016 0.0222
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0029 0.0125 0.0129
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0137 0.1043 0.1038
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0481 0.395 0.474
Schistosoma mansoni amine GPCR 0.0045 0.0262 0.0257
Echinococcus multilocularis jumonji domain containing 1A 0.003 0.0139 0.0134
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0116 0.0865 0.1069
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0481 0.395 0.474
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0262 0.0257
Schistosoma mansoni sodium/chloride dependent transporter 0.0106 0.0774 0.077
Chlamydia trachomatis DNA gyrase subunit B 0.0347 0.2816 0.7104
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0123 0.092 0.1086
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0481 0.395 0.474
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0151 0.116 0.1156
Trypanosoma cruzi trypanothione reductase, putative 0.0999 0.8328 1
Brugia malayi hypothetical protein 0.0045 0.0262 0.0308
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0481 0.395 0.6136
Onchocerca volvulus 0.0128 0.0961 0.1182
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0115 0.0152
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0045 0.0262 0.0257
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0033 0.0033
Loa Loa (eye worm) programmed cell death 8 0.0128 0.0961 0.1149
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0262 0.0257
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0074 0.0069
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0096 0.0091
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0128 0.0961 0.1473
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Plasmodium falciparum ferrodoxin reductase-like protein 0.0128 0.0961 0.1119
Leishmania major DNA damage repair protein, putative 0.0021 0.0062 0.0069
Brugia malayi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0071 0.0484 0.0575
Onchocerca volvulus 0.004 0.0215 0.026
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0045 0.0262 0.0257
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0096 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0892 0.1066
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0056 0.0046
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0215 0.0253
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0287 0.2308 0.2757
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0352 0.0417
Loa Loa (eye worm) G-protein coupled receptor 0.0045 0.0262 0.0308
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0037 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.1028 0.1271
Echinococcus multilocularis neuropeptide receptor A26 0.097 0.8082 0.8081
Schistosoma mansoni hypothetical protein 0.0045 0.0262 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.1028 0.1271
Schistosoma mansoni inositol monophosphatase 0.0036 0.0189 0.0184
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0037 0.0038
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.019 0.149 0.2299
Brugia malayi Pre-SET motif family protein 0.0853 0.7095 0.8519
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0215 0.0211
Brugia malayi hypothetical protein 0.0045 0.0262 0.0308
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0139 0.016
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0027 0.0107 0.0132
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0481 0.395 0.4722
Trypanosoma cruzi DNA topoisomerase II, putative 0.0713 0.5907 0.7091
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0046 0.0035
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.0213 0.0255
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0128 0.0961 0.1473
Mycobacterium ulcerans hypothetical protein 0.0028 0.0115 0.0152
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0439 0.3595 0.9081
Loa Loa (eye worm) hypothetical protein 0.0072 0.049 0.0582
Echinococcus multilocularis caspase 3 0.0223 0.1766 0.1762
Schistosoma mansoni apoferritin-2 0.0025 0.0091 0.0086
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0039 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0215 0.0253
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0045 0.0262 0.0257
Schistosoma mansoni glutamate synthase 0.0128 0.0961 0.0957
Onchocerca volvulus 0.0028 0.0115 0.0136
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0262 0.0257
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0481 0.395 1
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.1028 0.1271
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.003 0.003
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0481 0.395 0.474
Loa Loa (eye worm) hypothetical protein 0.0021 0.0056 0.0061
Echinococcus granulosus fmrfamide receptor 0.0045 0.0262 0.0257
Schistosoma mansoni nuclear receptor 0.0019 0.0039 0.0034
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Chlamydia trachomatis DNA gyrase subunit A 0.0162 0.1251 0.311
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0215 0.0211
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0067 0.0443 0.0548
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0151 0.116 0.1388
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0128 0.0961 0.0957
Schistosoma mansoni ap endonuclease 0.0055 0.0346 0.0342
Schistosoma mansoni hypothetical protein 0.0098 0.0712 0.0708
Mycobacterium tuberculosis Conserved hypothetical protein 0.0067 0.0443 0.0512
Brugia malayi putative neuropeptide receptor 0.0045 0.0262 0.0308
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0046 0.0035
Loa Loa (eye worm) hypothetical protein 0.03 0.242 0.2902
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0262 0.0257
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0128 0.0961 0.2255
Plasmodium falciparum lysophospholipase, putative 0.0793 0.6586 0.7901
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Trypanosoma cruzi Serine peptidase, Clan SC, Family S09X, putative 0.0067 0.0443 0.0527
Loa Loa (eye worm) thioredoxin reductase 0.0999 0.8328 1
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0276 0.0341
Trichomonas vaginalis conserved hypothetical protein 0.0774 0.6426 0.7943
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.012 0.0149
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0481 0.395 0.474
Trypanosoma cruzi monoglyceride lipase, putative 0.0774 0.6426 0.7715
Echinococcus granulosus dro:myosuppressin receptor 0.0045 0.0262 0.0257
Schistosoma mansoni flap endonuclease-1 0.0027 0.0113 0.0108
Brugia malayi Globin family protein 0.0016 0.0017 0.0015
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0481 0.395 0.4722
Schistosoma mansoni protein phosphatase 2C 0.003 0.0139 0.0134
Plasmodium falciparum alpha/beta hydrolase, putative 0.0067 0.0443 0.0495
Entamoeba histolytica hypothetical protein 0.0075 0.0514 0.0715
Onchocerca volvulus 0.0045 0.0262 0.0317
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0067 0.0443 0.0548
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0046 0.0056
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0352 0.0417
Mycobacterium leprae Probable two-component sensor kinase 0.0039 0.0213 0.0257
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0023
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0023 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0052
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0037 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0262 0.0257
Loa Loa (eye worm) hypothetical protein 0.0044 0.0252 0.0296
Plasmodium vivax thioredoxin reductase, putative 0.0999 0.8328 1
Brugia malayi nuclear receptor NHR-88 0.0019 0.0039 0.0041
Echinococcus granulosus voltage dependent calcium channel 0.0083 0.0586 0.0581
Echinococcus granulosus mitogen activated protein kinase 3 0.0047 0.0276 0.0271
Trypanosoma brucei heat shock protein, putative 0.0039 0.0213 0.025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Brugia malayi GnHR receptor homolog 0.0045 0.0262 0.0308
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.039 0.0462
Brugia malayi ecdysteroid receptor 0.004 0.0215 0.0253
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.093 0.0925
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0136 0.0158
Onchocerca volvulus 0.0045 0.0262 0.0317
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0125 0.0144
Echinococcus granulosus ubiquitin specific protease 41 0.0151 0.116 0.1156
Brugia malayi sulfakinin receptor protein 0.0045 0.0262 0.0308
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0128 0.0961 0.1119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.021 0.026
Trypanosoma brucei monoglyceride lipase, putative 0.0774 0.6426 0.7715
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0018 0.0033 0.0033
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0123 0.092 0.11
Echinococcus multilocularis acetylcholinesterase 0.0158 0.1216 0.1212
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0041 0.0225 0.0276
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0138 0.0126
Trypanosoma brucei Heat shock protein 83, putative 0.0039 0.0213 0.025
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0028 0.0115 0.0152
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0115 0.0117
Loa Loa (eye worm) globin family protein 0.0016 0.0017 0.0015
Brugia malayi isocitrate dehydrogenase 0.0018 0.0037 0.0038
Mycobacterium ulcerans NADH dehydrogenase 0.0128 0.0961 0.1473
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0067 0.0443 0.0527
Brugia malayi hypothetical protein 0.0045 0.0262 0.0308
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0018 0.0033 0.0028
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0046 0.005
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0754 0.6251 0.7504
Echinococcus multilocularis phd:f box containing protein 0.003 0.0139 0.0134
Loa Loa (eye worm) hypothetical protein 0.0307 0.2472 0.2964
Echinococcus multilocularis apoptotic protease activating factor 1 0.0126 0.0949 0.0945
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0039 0.0213 0.0257
Echinococcus multilocularis neuropeptides capa receptor 0.0045 0.0262 0.0257
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0067 0.0443 0.0439
Loa Loa (eye worm) hypothetical protein 0.0106 0.0774 0.0924
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0151 0.116 0.1388
Mycobacterium tuberculosis Conserved hypothetical protein 0.032 0.2585 0.309
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0233 0.0288
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0236 0.0292
Loa Loa (eye worm) TYRA-2 protein 0.0045 0.0262 0.0308
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0055 0.0346 0.041
Leishmania major DNA polymerase kappa, putative 0.0082 0.0571 0.068
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0045 0.0262 0.0257
Echinococcus multilocularis lysine specific demethylase 6a 0.003 0.0139 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0443 0.0527
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0481 0.395 0.3947
Echinococcus granulosus cpg binding protein 0.0089 0.0632 0.0627
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0128 0.0961 0.143
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0125 0.0144
Trypanosoma brucei DNA polymerase IV, putative 0.0107 0.0786 0.0938
Echinococcus granulosus caspase 8 0.0136 0.1028 0.1023
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0103
Plasmodium falciparum alpha/beta hydrolase, putative 0.0067 0.0443 0.0495
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0033 0.0033
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0055 0.0346 0.0662
Mycobacterium tuberculosis Carboxylesterase LipT 0.0027 0.0107 0.0108
Echinococcus multilocularis microtubule associated protein 2 0.068 0.563 0.5627
Schistosoma mansoni myoglobin 1 0.0016 0.0017 0.0012
Chlamydia trachomatis DNA gyrase subunit B 0.0439 0.3595 0.9095
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0047 0.0276 0.0325
Plasmodium vivax ferrodoxin reductase, putative 0.0128 0.0961 0.1119
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0039 0.0213 0.0263
Loa Loa (eye worm) RecQ helicase 0.002 0.0046 0.005
Trypanosoma brucei heat shock protein, putative 0.0039 0.0213 0.025
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0853 0.7095 0.8519
Onchocerca volvulus 0.0027 0.0107 0.0126
Loa Loa (eye worm) hypoxia-induced factor 1 0.0138 0.1047 0.1252
Schistosoma mansoni hypothetical protein 0.0045 0.0262 0.0257
Toxoplasma gondii cytochrome p450 superfamily protein 0.0029 0.0125 0.0144
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0039 0.0034
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0055 0.0346 0.0511
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0146 0.018
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0139 0.016
Schistosoma mansoni adenoreceptor 0.0045 0.0262 0.0257
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0039 0.0213 0.0235
Echinococcus multilocularis thioredoxin glutathione reductase 0.0999 0.8328 0.8327
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0215 0.0211
Schistosoma mansoni ferritin light chain 0.0025 0.0091 0.0086
Echinococcus multilocularis neuropeptide receptor 0.0045 0.0262 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.012 0.0149
Plasmodium vivax hypothetical protein, conserved 0.0067 0.0443 0.0495
Mycobacterium ulcerans bacterioferritin BfrA 0.0025 0.0091 0.0115
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.003 0.0139 0.0134
Echinococcus granulosus orexin receptor type 2 0.0045 0.0262 0.0257
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0215 0.0211
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0273 0.0321
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0128 0.0961 0.1149
Plasmodium falciparum glutathione reductase 0.0481 0.395 0.4722
Echinococcus multilocularis lamin 0.0051 0.0315 0.031
Schistosoma mansoni heat shock protein 0.0039 0.0213 0.0208
Loa Loa (eye worm) hypothetical protein 0.0021 0.0056 0.0061
Toxoplasma gondii esterase/lipase/thioesterase domain-containing protein 0.0067 0.0443 0.0527
Echinococcus granulosus hypothetical protein 0.0045 0.0262 0.0257
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0045 0.0262 0.0257
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0128 0.0961 0.1136
Trypanosoma cruzi target of rapamycin kinase 3 0.0042 0.0234 0.0275
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0039 0.0213 0.0305
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0162 0.1251 0.1485
Echinococcus granulosus voltage gated potassium channel 0.0023 0.0074 0.0069
Schistosoma mansoni glutamate synthase 0.0128 0.0961 0.0957
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.003 0.0037
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0128 0.0961 0.1149
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.039 0.0462
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.003 0.003
Plasmodium falciparum exported lipase 1 0.0067 0.0443 0.0495
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0481 0.395 0.474
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0215 0.0253
Entamoeba histolytica DNA topoisomerase II, putative 0.0754 0.6251 0.9487
Brugia malayi nuclear receptor NHR-67 0.0019 0.0039 0.0041
Onchocerca volvulus 0.0027 0.0107 0.0126
Schistosoma mansoni histamine h1 receptor 0.0045 0.0262 0.0257
Brugia malayi follicle stimulating hormone receptor 0.0256 0.2042 0.2448
Brugia malayi Muscleblind-like protein 0.03 0.242 0.2902
Onchocerca volvulus 0.0045 0.0262 0.0317
Echinococcus granulosus neuropeptide receptor 0.0045 0.0262 0.0257
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Echinococcus multilocularis para nitrobenzyl esterase 0.0027 0.0107 0.0102
Brugia malayi Uncoordinated protein 44 0.0017 0.0023 0.0021
Echinococcus granulosus FTZ F1 alpha 0.004 0.0215 0.0211
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0067 0.0443 0.0548
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0039 0.0213 0.025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Trypanosoma brucei protein kinase, putative 0.0047 0.0276 0.0325
Mycobacterium ulcerans DNA gyrase subunit B 0.0439 0.3595 0.5583
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0128 0.0961 0.1188
Loa Loa (eye worm) doublecortin family protein 0.0023 0.0075 0.0085
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0033
Giardia lamblia DNA damage repair protein 0.0021 0.0062 0.0027
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0128 0.0961 0.1149
Schistosoma mansoni DNA helicase recq1 0.002 0.0046 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0124 0.0929 0.0925
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0042 0.0234 0.0275
Brugia malayi jmjC domain containing protein 0.0119 0.0887 0.1059
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0042 0.0052
Loa Loa (eye worm) hypothetical protein 0.0151 0.116 0.1388
Echinococcus granulosus neuropeptide Y receptor 0.0045 0.0262 0.0257
Echinococcus multilocularis monoacylglycerol lipase abhd12 0.0067 0.0443 0.0439
Echinococcus multilocularis acetylcholinesterase 0.0158 0.1216 0.1212
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0116 0.0865 0.1033
Trypanosoma cruzi serine peptidase, putative 0.0067 0.0443 0.0527
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0051 0.0315 0.0372
Schistosoma mansoni 60S ribosomal protein L21 0.0018 0.0033 0.0028
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.003 0.003
Schistosoma mansoni thyroid hormone receptor 0.0164 0.1264 0.126
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0039 0.0034
Schistosoma mansoni neuropeptide receptor 0.0045 0.0262 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.1028 0.1271
Brugia malayi Protein C20orf22 0.0067 0.0443 0.0527
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0207 0.021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.012 0.0148
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0056 0.0351 0.0415
Chlamydia trachomatis hydrolase 0.0067 0.0443 0.1048
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.0051 0.0315 0.0372
Mycobacterium ulcerans aldehyde dehydrogenase 0.0056 0.0351 0.0521
Loa Loa (eye worm) hypothetical protein 0.03 0.242 0.2902
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0015
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0352 0.0417
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0213 0.025
Brugia malayi jmjC domain containing protein 0.003 0.0139 0.016
Trichomonas vaginalis set domain proteins, putative 0.0971 0.809 1
Loa Loa (eye worm) heat shock protein 90 0.0039 0.0213 0.025
Toxoplasma gondii exonuclease III APE 0.0055 0.0346 0.041
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0189 0.0254
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0215 0.0211
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0588 0.4849 0.7344
Loa Loa (eye worm) hypothetical protein 0.0021 0.0056 0.0061
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0262 0.0257
Leishmania major DNA topoisomerase III, putative 0.0041 0.0225 0.0264
Trichomonas vaginalis spcc417.12 protein, putative 0.0027 0.0107 0.0132
Plasmodium falciparum metacaspase 1 0.0136 0.1028 0.12
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0128 0.0961 0.0957
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0045 0.0262 0.0257
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0046 0.0041
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0139 0.0134
Plasmodium vivax PST-A protein 0.0067 0.0443 0.0495
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0287 0.2311 0.2771
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0045 0.0262 0.0308
Brugia malayi neuropeptide F receptor 0.0045 0.0262 0.0308
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0029 0.0125 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0276 0.0271
Mycobacterium ulcerans lysophospholipase 0.0774 0.6426 1
Plasmodium vivax lysophospholipase, putative 0.0067 0.0443 0.0495
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0039 0.0034
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0713 0.5907 0.7091
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0039 0.0041
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0023 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.4849 0.5995
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0029 0.0125 0.0168
Trichomonas vaginalis receptor histidine kinase, putative 0.0039 0.0213 0.0263
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.012 0.0892 0.1103
Echinococcus multilocularis thyroid hormone receptor alpha 0.0164 0.1264 0.126
Loa Loa (eye worm) cytochrome P450 0.0029 0.0125 0.0144
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0151 0.116 0.1897
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0039 0.0213 0.025
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0189 0.0234
Loa Loa (eye worm) serotonin transporter b 0.0106 0.0774 0.0924
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0042 0.0052
Brugia malayi Cell death protein 3 precursor 0.0262 0.2096 0.2512
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0046 0.0041
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0039 0.0034
Loa Loa (eye worm) calcium channel 0.0142 0.108 0.1292
Trypanosoma cruzi DNA topoisomerase III, putative 0.0041 0.0225 0.0264
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0207 0.0245
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0074 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0233 0.0288
Trypanosoma brucei unspecified product 0.0048 0.0284 0.0335
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0128 0.0961 0.1188
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0128 0.0961 0.1473
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0045 0.0262 0.0257
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0039 0.0213 0.0257
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0115 0.0105
Treponema pallidum hypothetical protein 0.0066 0.0436 0.0725
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0262 0.0257
Echinococcus granulosus bloom syndrome protein 0.002 0.0046 0.0041
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0037 0.0023
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0213 0.025
Loa Loa (eye worm) hypothetical protein 0.0126 0.0949 0.1134
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.0514 0.0509
Trypanosoma brucei cytochrome P450, putative 0.0056 0.0352 0.0417
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0047 0.0276 0.0325
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0115 0.0132
Trichomonas vaginalis aldehyde oxidase, putative 0.0404 0.3294 0.4072
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0215 0.026
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.003 0.0025
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0481 0.395 0.6136
Brugia malayi olfactory channel protein osm-9 0.0015 0.0006 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0233 0.0288
Loa Loa (eye worm) glutathione reductase 0.0999 0.8328 1
Leishmania major DNA topoisomerase III, putative 0.0041 0.0225 0.0264
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0018 0.0033 0.0028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0075 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.012 0.0149
Brugia malayi Dopamine receptor protein 2 0.0045 0.0262 0.0308
Onchocerca volvulus Globin homolog 0.0016 0.0017 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.049 0.0582
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.0016 0.0017 0.0015
Plasmodium falciparum BEM46-like protein, putative 0.0067 0.0443 0.0495
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0123 0.092 0.1409
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0128 0.0961 0.1399
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0052 0.0324 0.0383
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0039 0.0213 0.025
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0046 0.0041
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.003 0.003
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0138 0.0159
Echinococcus granulosus expressed protein 0.0025 0.0091 0.0086
Echinococcus granulosus mitogen activated protein kinase 0.0047 0.0276 0.0271
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0115 0.0152
Trypanosoma cruzi NADH dehydrogenase, putative 0.0128 0.0961 0.1149
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0096 0.0091
Schistosoma mansoni disulfide oxidoreductase 0.0128 0.0961 0.0957
Giardia lamblia Kinase, CMGC MAPK 0.0047 0.0276 0.039
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0236 0.0278
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0045 0.0262 0.0257
Plasmodium falciparum glutathione reductase 0.0999 0.8328 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0128 0.0961 0.1188
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0115 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0042 0.0052
Brugia malayi hypothetical protein 0.0126 0.0949 0.1134
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0018 0.0033 0.0033
Brugia malayi Death domain containing protein 0.0017 0.0023 0.0021
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0067 0.0443 0.0548
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0151 0.116 0.1703
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0046 0.0041
Echinococcus multilocularis muscleblind protein 0.03 0.242 0.2417
Trypanosoma cruzi NADH dehydrogenase, putative 0.0128 0.0961 0.1149
Echinococcus granulosus sex peptide receptor 0.0045 0.0262 0.0257
Schistosoma mansoni thyroid hormone receptor 0.0164 0.1264 0.126
Trypanosoma cruzi DNA damage repair protein, putative 0.0021 0.0062 0.0069
Echinococcus multilocularis sodium and chloride dependent glycine 0.0018 0.0033 0.0028
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0287 0.2308 0.3575
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0142 0.108 0.1076
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0063
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.0213 0.0255
Trypanosoma brucei DNA damage repair protein, putative 0.0021 0.0062 0.0069
Giardia lamblia DNA topoisomerase III 0.0041 0.0225 0.0304
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0189 0.0234
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0128 0.0961 0.1399
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0151 0.116 0.1388
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0046 0.0041
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0359 0.2913 0.2909
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0033 0.0028
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0136 0.1028 0.1271
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0129 0.0117
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0128 0.0961 0.0957
Leishmania major DNA topoisomerase ii 0.0713 0.5907 0.7091
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0093
Loa Loa (eye worm) DR-78 0.0019 0.0039 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.012 0.0149
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0037 0.0038
Echinococcus multilocularis sodium channel protein 0.0056 0.0351 0.0346
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0114 0.0846 0.0842
Giardia lamblia Pms1-like protein 0.0039 0.0213 0.0284
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.4849 0.5995
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0039 0.0034
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0047 0.0276 0.0325
Echinococcus granulosus microtubule associated protein 2 0.068 0.563 0.5627
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0045 0.0262 0.0308
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0041 0.0225 0.0264
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0481 0.395 0.474
Onchocerca volvulus Neuropeptide F receptor homolog 0.0045 0.0262 0.0317
Echinococcus granulosus nuclear factor of activated T cells 5 0.0086 0.0607 0.0602
Schistosoma mansoni DNA topoisomerase II 0.0754 0.6251 0.6249
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Brugia malayi jmjC domain containing protein 0.003 0.0139 0.016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.4849 0.5995
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0058 0.0053
Loa Loa (eye worm) hypothetical protein 0.0028 0.0115 0.0132
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0027 0.0107 0.0102
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0128 0.0961 0.1149
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0876 0.0871
Brugia malayi Globin family protein 0.0016 0.0017 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0042 0.0052
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0052 0.0324 0.0424
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Echinococcus multilocularis Phospholipase carboxylesterase 0.0067 0.0443 0.0439
Echinococcus multilocularis allatostatin A receptor 0.0045 0.0262 0.0257
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0892 0.1066
Loa Loa (eye worm) hypothetical protein 0.0069 0.0465 0.0552
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0029 0.0125 0.0129
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0168 0.0208
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Brugia malayi G-protein coupled receptor 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0215 0.0211
Schistosoma mansoni hypothetical protein 0.0128 0.0961 0.0957
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0019 0.0042 0.0052
Schistosoma mansoni lamin 0.0051 0.0315 0.031
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0049 0.0292 0.0345
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0162 0.1251 0.1497
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0929 0.0925
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0039 0.0213 0.0217
Schistosoma mansoni lipoxygenase 0.0137 0.1043 0.1038
Loa Loa (eye worm) hypothetical protein 0.0106 0.0774 0.0924
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0029 0.0125 0.0168
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0509 0.4185 0.517
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0058 0.0063
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0091 0.0103
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Mycobacterium ulcerans DNA polymerase IV 0.012 0.0892 0.1365
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0046 0.0041
Echinococcus multilocularis g-protein coupled receptor 0.0045 0.0262 0.0257
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Brugia malayi ORL1-like opioid receptor 0.0045 0.0262 0.0308
Giardia lamblia DNA topoisomerase III 0.0041 0.0225 0.0304
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0352 0.0417
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0047 0.0276 0.0325
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0029 0.0125 0.0129
Echinococcus granulosus transient receptor potential cation channel 0.0015 0.0006 0.0001
Schistosoma mansoni aryl hydrocarbon receptor 0.0045 0.0258 0.0253
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0023 0.0074 0.0083
Trypanosoma brucei DNA topoisomerase III, putative 0.0041 0.0225 0.0264
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0136 0.1034 0.1586
Onchocerca volvulus 0.0018 0.0033 0.0034
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0052 0.0324 0.0383
Treponema pallidum fructose-bisphosphate aldolase 0.0588 0.4849 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0215 0.0253
Onchocerca volvulus 0.0045 0.0262 0.0317
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0082 0.0571 0.068
Echinococcus multilocularis transient receptor potential cation channel 0.0015 0.0006 0.0001
Brugia malayi hypothetical protein 0.0016 0.0017 0.0015
Echinococcus multilocularis bloom syndrome protein 0.002 0.0046 0.0041
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0045 0.0262 0.0257
Toxoplasma gondii peptidase S15, putative 0.0067 0.0443 0.0527
Giardia lamblia 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0116 0.0865 0.1394
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0075 0.007
Schistosoma mansoni single-minded 0.0045 0.0258 0.0253
Plasmodium falciparum alpha/beta hydrolase, putative 0.0067 0.0443 0.0495
Schistosoma mansoni hypothetical protein 0.0126 0.0949 0.0945
Echinococcus multilocularis dna polymerase eta 0.0069 0.0465 0.046
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0136 0.1028 0.1023
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0045 0.0262 0.0308
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0276 0.0341
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0136 0.1028 0.1271
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0046 0.0057
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0039 0.0213 0.0235
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0045 0.0262 0.0257
Loa Loa (eye worm) hypothetical protein 0.0067 0.0443 0.0527
Loa Loa (eye worm) hypothetical protein 0.0067 0.0443 0.0527
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0045 0.0262 0.0257
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0215 0.0211
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0039 0.0034
Trypanosoma cruzi metacaspase, putative 0.0136 0.1028 0.1229
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0142 0.108 0.1076
Brugia malayi DNA topoisomerase III beta-1 0.0041 0.0225 0.0264
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0041 0.0225 0.0264
Toxoplasma gondii hypothetical protein 0.0098 0.0709 0.0846
Brugia malayi Carboxylesterase family protein 0.0027 0.0107 0.0122
Echinococcus granulosus calcium activated potassium channel 0.0015 0.0009 0.0004
Schistosoma mansoni inositol monophosphatase 0.0036 0.0189 0.0184
Mycobacterium ulcerans epimerase 0.002 0.0049 0.0049
Brugia malayi Inositol-1 0.0036 0.0189 0.0221
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0018 0.0033 0.0028
Brugia malayi Cytochrome P450 family protein 0.0046 0.0273 0.0321
Echinococcus multilocularis mitogen activated protein kinase 3 0.0047 0.0276 0.0271
Echinococcus granulosus voltage dependent calcium channel 0.0142 0.108 0.1076
Schistosoma mansoni neuropeptide f receptor 76f 0.0045 0.0262 0.0257
Brugia malayi glutamate synthase 0.0128 0.0961 0.1149
Echinococcus granulosus carboxylesterase 5A 0.0158 0.1216 0.1212
Trichomonas vaginalis helicase, putative 0.0019 0.0042 0.0052
Onchocerca volvulus 0.0084 0.0592 0.0726
Toxoplasma gondii histone lysine methyltransferase SET1 0.0167 0.1295 0.155
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0045 0.0262 0.0257
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0062 0.0069
Mycobacterium ulcerans two component sensor kinase MprB 0.0039 0.0213 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0443 0.0548
Schistosoma mansoni cytochrome P450 0.0029 0.0125 0.012
Trypanosoma cruzi serine peptidase, putative 0.0067 0.0443 0.0527
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0215 0.0253
Echinococcus granulosus lysine specific demethylase 5A 0.0119 0.0887 0.0882
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0215 0.0211
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0215 0.0211
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0075 0.007
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0067 0.0443 0.0527
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0023 0.0018
Onchocerca volvulus 0.0027 0.0107 0.0126
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0128 0.0961 0.143
Schistosoma mansoni endoplasmin 0.0039 0.0213 0.0208
Trypanosoma cruzi metacaspase, putative 0.0136 0.1028 0.1229
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0037 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0029 0.0125 0.0129
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0138 0.017
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.009 0.0085
Entamoeba histolytica hypothetical protein 0.0067 0.0443 0.0607
Trypanosoma brucei unspecified product 0.0107 0.0786 0.0938
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0151 0.116 0.1156
Loa Loa (eye worm) hypothetical protein 0.0262 0.2096 0.2512
Echinococcus multilocularis mitogen activated protein kinase 0.0047 0.0276 0.0271
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0046 0.0035
Echinococcus multilocularis RUN 0.0023 0.0075 0.007
Leishmania major developmentally regulated phosphoprotein-like protein 0.0039 0.0213 0.025
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0602 0.4969 0.7716
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0037 0.0005
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0142 0.108 0.1076
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0136 0.1028 0.1271
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0215 0.0253
Onchocerca volvulus 0.0124 0.0929 0.1143
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0042 0.0052
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0045 0.0262 0.0257
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0115 0.0132
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0056 0.0058
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0085 0.0603 0.0719
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0262 0.0257
Brugia malayi Cyclic-nucleotide gated cation channel 0.0019 0.0046 0.0049
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0151 0.116 0.1156
Brugia malayi exodeoxyribonuclease III family protein 0.0055 0.0346 0.041
Loa Loa (eye worm) hypothetical protein 0.051 0.4192 0.503
Brugia malayi hypothetical protein 0.0149 0.1145 0.1369
Toxoplasma gondii NADPH-glutathione reductase 0.0481 0.395 0.474
Schistosoma mansoni globin X 0.0016 0.0017 0.0012
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0062 0.0069
Schistosoma mansoni jumonji domain containing protein 0.0114 0.0846 0.0842
Trichomonas vaginalis ferritin, putative 0.0025 0.0091 0.0112
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0029 0.0125 0.0129
Loa Loa (eye worm) hypothetical protein 0.0027 0.0108 0.0124
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0055 0.0346 0.0378
Echinococcus granulosus glutamate synthase 0.0128 0.0961 0.0957
Trypanosoma cruzi DNA topoisomerase II, putative 0.0713 0.5907 0.7091
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0189 0.0221
Brugia malayi GRF zinc finger family protein 0.0041 0.0225 0.0264
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0039 0.0034
Onchocerca volvulus 0.0016 0.0017 0.0015
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0039 0.0042
Plasmodium vivax lysophospholipase, putative 0.0793 0.6586 0.7901
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.021 0.026
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0509 0.4185 0.517
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0041 0.0225 0.022
Echinococcus multilocularis tumor protein p63 0.1036 0.8639 0.8639
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0142 0.108 0.1292
Leishmania major DNA topoisomerase 1A 0.0041 0.0225 0.0264
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0058 0.0063
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.1055 0.105
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0774 0.6426 0.7943
Schistosoma mansoni neuroligin 3 (S09 family) 0.0027 0.0107 0.0102
Schistosoma mansoni polycystin 1-related 0.0023 0.0075 0.007
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0067 0.0443 0.0527
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0085 0.0603 0.0719
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0029 0.0125 0.0129
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0018 0.0033 0.0028
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0481 0.395 0.474
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0128 0.0961 0.1188
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0142 0.108 0.1076
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0189 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0892 0.1066
Leishmania major hypothetical protein, conserved 0.0128 0.0961 0.1149
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0139 0.016
Brugia malayi nuclear receptor NHR-88 0.004 0.0215 0.0253
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0481 0.395 0.4722
Brugia malayi G protein-coupled receptor 0.0045 0.0262 0.0308
Echinococcus granulosus Ankyrin 0.0017 0.0024 0.0019
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0049 0.0055
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0439 0.3595 0.7365
Plasmodium falciparum DNA gyrase subunit A 0.0162 0.1251 0.1469
Leishmania major hypothetical protein, conserved 0.0039 0.0213 0.025
Trypanosoma brucei heat shock protein, putative 0.0039 0.0213 0.025
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0039 0.0213 0.0235
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0262 0.0257
Trichomonas vaginalis DNA topoisomerase II, putative 0.0754 0.6251 0.7727
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.000000061828
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.052 0.0618
Echinococcus multilocularis fmrfamide receptor 0.0045 0.0262 0.0257
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0021
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0128 0.0961 0.1149
Loa Loa (eye worm) hypothetical protein 0.0104 0.0757 0.0903
Chlamydia trachomatis DNA gyrase subunit A 0.0162 0.1251 0.311
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0029 0.0125 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0215 0.0253
Treponema pallidum oxidoreductase 0.0128 0.0961 0.1829
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0029 0.0125 0.0129
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0041 0.0225 0.022
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0128 0.0961 0.0957
Brugia malayi conserved hypotetical protein 0.0019 0.0039 0.0041
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.003 0.0025
Mycobacterium ulcerans ferredoxin reductase 0.0128 0.0961 0.1473
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0128 0.0961 0.1149
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0443 0.0548
Brugia malayi neuropeptide F receptor 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.0128 0.0961 0.1149
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0021 0.0016
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0128 0.0961 0.0957
Brugia malayi ecdysone receptor 0.0019 0.0039 0.0041
Schistosoma mansoni DNA helicase recq5 0.002 0.0046 0.0041
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0481 0.395 0.474
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0019 0.0046 0.0041
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0037 0.0038
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0023 0.0018
Echinococcus multilocularis neuropeptides capa receptor 0.0045 0.0262 0.0257
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0215 0.0253
Schistosoma mansoni amine GPCR 0.0045 0.0262 0.0257
Echinococcus multilocularis dro:myosuppressin receptor 0.0045 0.0262 0.0257
Echinococcus multilocularis muscleblind protein 1 0.03 0.242 0.2417
Echinococcus multilocularis cpg binding protein 0.0089 0.0632 0.0627
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0033 0.0033
Schistosoma mansoni cellular tumor antigen P53 0.0152 0.1163 0.1159
Echinococcus granulosus short transient receptor potential channel 6 0.0015 0.0006 0.0001
Echinococcus granulosus para nitrobenzyl esterase 0.0027 0.0107 0.0102
Schistosoma mansoni hypothetical protein 0.0322 0.2604 0.2601
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0055 0.0346 0.0342
Entamoeba histolytica DNA topoisomerase III, putative 0.0041 0.0225 0.0273
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0046 0.0041
Mycobacterium leprae Conserved hypothetical protein 0.0029 0.0125 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.039 0.0462
Brugia malayi jmjC domain containing protein 0.003 0.0139 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0892 0.1066
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0077 0.0533 0.062
Schistosoma mansoni amine GPCR 0.0045 0.0262 0.0257
Brugia malayi MGC83647 protein 0.0067 0.0443 0.0527
Toxoplasma gondii DNA topoisomerase 2, putative 0.0754 0.6251 0.7504
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0215 0.0253
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0162 0.1251 0.3007
Echinococcus granulosus cytochrome P450 2K1 0.0029 0.0125 0.012
Schistosoma mansoni intermediate filament proteins 0.0051 0.0315 0.031
Onchocerca volvulus 0.0045 0.0262 0.0317
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.093 0.0925
Echinococcus granulosus sodium and chloride dependent glycine 0.0018 0.0033 0.0028
Loa Loa (eye worm) hypothetical protein 0.051 0.4192 0.503
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0055 0.0346 0.041
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0138 0.0156
Onchocerca volvulus 0.0045 0.0262 0.0317
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0189 0.0234
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.032 0.0315
Schistosoma mansoni opsin-like receptor 0.0045 0.0262 0.0257
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0189 0.0218
Schistosoma mansoni endoplasmin 0.0039 0.0213 0.0208
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0136 0.1028 0.1271
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0158 0.1216 0.1212
Toxoplasma gondii endonuclease IV APN 0.0076 0.052 0.0618
Onchocerca volvulus 0.0045 0.0262 0.0317
Treponema pallidum hypothetical protein 0.0054 0.0338 0.0519
Brugia malayi Carboxylesterase family protein 0.0158 0.1216 0.1456
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0151 0.116 0.1156
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0037 0.0038
Echinococcus granulosus dna polymerase eta 0.0069 0.0465 0.046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Plasmodium falciparum flap endonuclease 1 0.003 0.0138 0.0126
Echinococcus granulosus lamin 0.0051 0.0315 0.031
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0324 0.0383
Plasmodium vivax heat shock protein 86, putative 0.0039 0.0213 0.0217
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0602 0.4969 0.5959
Brugia malayi hypothetical protein 0.0019 0.0042 0.0044
Brugia malayi hypothetical protein 0.0023 0.0075 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0146 0.018
Schistosoma mansoni heat shock protein 0.0039 0.0213 0.0208
Mycobacterium tuberculosis Probable two component sensor kinase 0.0039 0.0213 0.0235
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0046 0.005
Echinococcus granulosus apoptotic protease activating factor 1 0.0126 0.0949 0.0945
Plasmodium falciparum alpha/beta hydrolase fold domain containing protein, putative 0.0067 0.0443 0.0495
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0178 0.022
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0287 0.2311 0.2771
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0039 0.0213 0.0208
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0892 0.1066
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0045 0.0262 0.0308
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.052 0.0738
Schistosoma mansoni peptidase 0.0067 0.0443 0.0439
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0029 0.0125 0.0168
Leishmania major NADH dehydrogenase, putative 0.0128 0.0961 0.1149
Plasmodium vivax multidomain scavenger receptor, putative 0.0023 0.0075 0.0051
Trypanosoma brucei Serine peptidase, Clan SC, Family S09X 0.0067 0.0443 0.0527
Echinococcus granulosus histone lysine methyltransferase setb 0.0124 0.0929 0.0925
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0046 0.005
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0069 0.0465 0.046
Schistosoma mansoni nuclear receptor 0.0019 0.0039 0.0034
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0033 0.0028
Leishmania major DNA polymerase eta, putative 0.0021 0.0062 0.0069
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0215 0.0211
Toxoplasma gondii hypothetical protein 0.0793 0.6586 0.7908
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0063
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0754 0.6251 0.6249
Brugia malayi hypothetical protein 0.0016 0.0017 0.0015
Schistosoma mansoni cpg binding protein 0.0089 0.0632 0.0627
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0115 0.0103
Trypanosoma brucei DNA polymerase IV, putative 0.012 0.0892 0.1066
Leishmania major mitochondrial DNA polymerase beta 0.0607 0.5015 0.602
Onchocerca volvulus 0.0018 0.0033 0.0034
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0039 0.0034
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0128 0.0961 0.143
Mycobacterium ulcerans aldehyde dehydrogenase 0.0056 0.0351 0.0521
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0047 0.0276 0.0325
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0128 0.0961 0.1149
Loa Loa (eye worm) endoplasmin 0.0039 0.0213 0.025
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0052 0.0324 0.0383
Echinococcus multilocularis dna polymerase kappa 0.012 0.0892 0.0887
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0028 0.0115 0.0152
Echinococcus multilocularis voltage dependent calcium channel 0.0142 0.108 0.1076
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0136 0.1028 0.1229
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0892 0.1066
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0262 0.0257
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.003 0.0025
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0085 0.0603 0.0719
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0039 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Onchocerca volvulus 0.0033 0.016 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.012 0.0148
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0027 0.0107 0.0102
Mycobacterium tuberculosis Conserved protein 0.0039 0.0213 0.0235
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0136 0.1028 0.1229
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0123 0.092 0.11
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0287 0.2308 0.3543
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0215 0.0211
Plasmodium vivax DNA topoisomerase 3, putative 0.0041 0.0225 0.0232
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0142 0.108 0.1076
Toxoplasma gondii hypothetical protein 0.0067 0.0443 0.0527
Schistosoma mansoni myosin xvIII 0.0045 0.0262 0.0257
Echinococcus granulosus serotonin transporter 0.0106 0.0774 0.077
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0046 0.005
Entamoeba histolytica 2,3-bisphosphoglycerate-independentphosphoglycerate mutase, putative 0.0064 0.0423 0.0576
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0039 0.0034
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0892 0.1066
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0056 0.0352 0.0522
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0041 0.0225 0.0278
Entamoeba histolytica hypothetical protein 0.0075 0.0514 0.0715
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0083 0.0586 0.0698
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0324 0.04
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0262 0.0257
Brugia malayi Carboxylesterase family protein 0.0027 0.0107 0.0122
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Echinococcus multilocularis expressed protein 0.0025 0.0091 0.0086
Loa Loa (eye worm) hypothetical protein 0.0149 0.1145 0.1369
Brugia malayi hypothetical protein 0.0045 0.0262 0.0308
Brugia malayi hypothetical protein 0.0016 0.0017 0.0015
Brugia malayi Serotonin receptor 0.0045 0.0262 0.0308
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.4849 0.5995
Entamoeba histolytica hypothetical protein 0.0075 0.0514 0.0715
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0065 0.0072
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0128 0.0961 0.1399
Plasmodium falciparum DNA gyrase subunit B 0.0439 0.3595 0.4295
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0215 0.0211
Plasmodium falciparum alpha/beta hydrolase, putative 0.0067 0.0443 0.0495
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.003 0.0139 0.016
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0267 0.2142 0.3316
Loa Loa (eye worm) hypothetical protein 0.0083 0.0586 0.0698
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Plasmodium falciparum prodrug activation and resistance esterase 0.0067 0.0443 0.0495
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0128 0.0961 0.1119
Brugia malayi ImpB/MucB/SamB family protein 0.0069 0.0465 0.0552
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.012 0.0148
Echinococcus granulosus 7TM GPCR rhodopsin 0.0045 0.0262 0.0257
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Schistosoma mansoni zinc finger protein 0.0019 0.0039 0.0034
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0052 0.0324 0.0424
Plasmodium falciparum metacaspase-like protein 0.0136 0.1028 0.12
Loa Loa (eye worm) hypothetical protein 0.004 0.0215 0.0253
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0115 0.0105
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0481 0.395 0.6136
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0039 0.0213 0.0235
Plasmodium vivax DNA gyrase subunit A, putative 0.0162 0.1251 0.1469
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0215 0.0253
Plasmodium vivax PST-A protein 0.0067 0.0443 0.0495
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0481 0.395 0.4732
Echinococcus multilocularis musashi 0.0051 0.0315 0.031
Trypanosoma brucei DNA polymerase eta, putative 0.0069 0.0465 0.0552
Schistosoma mansoni opsin-like receptor 0.0045 0.0262 0.0257
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0062 0.0069
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0023 0.0018
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0046 0.0016
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0053
Schistosoma mansoni gliotactin 0.0027 0.0107 0.0102
Mycobacterium ulcerans hypothetical protein 0.002 0.0049 0.0049
Echinococcus granulosus neuropeptide s receptor 0.097 0.8082 0.8081
Schistosoma mansoni biogenic amine receptor 0.0045 0.0262 0.0257
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0213 0.025
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0046 0.0041
Toxoplasma gondii heat shock protein HSP90 0.0039 0.0213 0.025
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0015
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0029 0.0125 0.0168
Echinococcus granulosus neuropeptide FF receptor 2 0.0045 0.0262 0.0257
Toxoplasma gondii thioredoxin reductase 0.0999 0.8328 1
Onchocerca volvulus 0.0045 0.0262 0.0317
Mycobacterium ulcerans bacterioferritin BfrB 0.0025 0.0091 0.0115
Schistosoma mansoni aldehyde dehydrogenase 0.0056 0.0351 0.0346
Loa Loa (eye worm) hypothetical protein 0.004 0.0215 0.0253
Leishmania major mitochondrial DNA topoisomerase II 0.0846 0.703 0.8441
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0033
Onchocerca volvulus 0.0019 0.0039 0.0042
Onchocerca volvulus 0.0051 0.0315 0.0383
Loa Loa (eye worm) hypothetical protein 0.003 0.0139 0.016
Brugia malayi kinase, mitochondrial precursor 0.0039 0.0213 0.025
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0067 0.0443 0.0548
Giardia lamblia GTOR 0.0052 0.0324 0.0473
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0033
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0039 0.0213 0.0316
Plasmodium vivax JmjC domain containing protein 0.003 0.0139 0.0127
Plasmodium falciparum LCCL domain-containing protein 0.0023 0.0075 0.0051
Brugia malayi cytoplasmic intermediate filament protein 0.0027 0.0113 0.013
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0128 0.0961 0.0957
Giardia lamblia DNA topoisomerase II 0.0714 0.5919 1
Brugia malayi hypothetical protein 0.0018 0.0033 0.0033
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0037 0.0038
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0128 0.0961 0.1136
Loa Loa (eye worm) neuropeptide F receptor 0.0045 0.0262 0.0308
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0774 0.6426 0.7943
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0169 0.0208
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0481 0.395 0.474
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0039 0.0034
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0067 0.0443 0.0548
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0846 0.703 0.8441
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0128 0.0961 0.1188
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0215 0.0253
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0037 0.0038
Mycobacterium tuberculosis Possible lysophospholipase 0.0774 0.6426 0.7711
Echinococcus granulosus biogenic amine 5HT receptor 0.0045 0.0262 0.0257
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0049 0.0053
Toxoplasma gondii hypothetical protein 0.0018 0.0033 0.0033
Echinococcus multilocularis heat shock protein 0.0039 0.0213 0.0208
Trichomonas vaginalis glutamate synthase, putative 0.0128 0.0961 0.1188
Toxoplasma gondii hypothetical protein 0.0067 0.0443 0.0527
Brugia malayi Serotonin receptor 0.0045 0.0262 0.0308
Brugia malayi Pre-SET motif family protein 0.0124 0.0929 0.111
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0077 0.0533 0.0804
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0015
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0029 0.0125 0.0144
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0024 0.0019
Trypanosoma brucei heat shock protein, putative 0.0039 0.0213 0.025
Echinococcus granulosus heat shock protein 90 0.0039 0.0213 0.0208
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0136 0.1034 0.1223
Toxoplasma gondii heat shock protein 90, putative 0.0039 0.0213 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0042 0.0052
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0039 0.0213 0.0305
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0128 0.0961 0.1149
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0041 0.0225 0.022
Echinococcus multilocularis neuropeptide Y receptor 0.0045 0.0262 0.0257
Brugia malayi Cytochrome P450 family protein 0.0056 0.0352 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0042 0.0052
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0128 0.0961 0.0957
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0215 0.0211
Trypanosoma brucei trypanothione reductase 0.0999 0.8328 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0039 0.0213 0.0235
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0128 0.0961 0.1188
Giardia lamblia Thioredoxin reductase 0.0128 0.0961 0.1558
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Plasmodium vivax PST-A protein 0.0774 0.6426 0.7707
Onchocerca volvulus 0.0023 0.0075 0.0087
Brugia malayi nuclear receptor RXR 0.0021 0.0058 0.0063
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0481 0.395 1
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0041 0.0225 0.0264
Echinococcus granulosus 7tm_1 domain containing protein 0.0045 0.0262 0.0257
Brugia malayi hypothetical protein 0.0021 0.0058 0.0063
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0157 0.0169
Schistosoma mansoni rab6-interacting 0.0023 0.0075 0.007
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0248 0.1981 0.3029
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0128 0.0961 0.0957
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0215 0.0211
Brugia malayi Cytochrome P450 family protein 0.0056 0.0352 0.0417
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0067 0.0443 0.0548
Echinococcus granulosus neuropeptides capa receptor 0.0045 0.0262 0.0257
Plasmodium falciparum lysophospholipase, putative 0.0774 0.6426 0.7707
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0151 0.116 0.1388
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Echinococcus granulosus alpha 1A adrenergic receptor 0.0045 0.0262 0.0257
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0029 0.0125 0.0168
Schistosoma mansoni rab6-interacting 0.0023 0.0075 0.007
Echinococcus granulosus peptide allatostatin:somatostatin 0.0045 0.0262 0.0257
Plasmodium falciparum alpha/beta-hydrolase, putative 0.0067 0.0443 0.0495
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0128 0.0961 0.2255
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0049 0.0292 0.0287
Mycobacterium tuberculosis Probable dehydrogenase 0.0248 0.1981 0.2362
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0276 0.0341
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0129 0.015
Plasmodium vivax alpha/beta hydrolase, putative 0.0067 0.0443 0.0495
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0046 0.0057
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0116 0.0865 0.1033
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.000000061828
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0443 0.0548
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0045 0.0262 0.0257
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0481 0.395 0.3947
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.019 0.149 0.1773
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0892 0.1066
Schistosoma mansoni jumonji/arid domain-containing protein 0.0119 0.0887 0.0882
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0196 0.1536 0.2332
Echinococcus granulosus acetylcholinesterase 0.0158 0.1216 0.1212
Schistosoma mansoni neuropeptide receptor 0.0045 0.0262 0.0257
Plasmodium falciparum esterase, putative 0.0774 0.6426 0.7707
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0157 0.0168
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0307 0.2472 0.2964
Treponema pallidum DNA topoisomerase I (topA) 0.0041 0.0225 0.0281
Schistosoma mansoni growth hormone secretagogue receptor 0.0045 0.0262 0.0257
Schistosoma mansoni biogenic amine (5HT) receptor 0.0045 0.0262 0.0257
Schistosoma mansoni sodium/chloride dependent transporter 0.0018 0.0036 0.0031
Onchocerca volvulus 0.0016 0.0017 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0215 0.0253
Schistosoma mansoni hypothetical protein 0.0075 0.0514 0.0509
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0039 0.0213 0.0305
Echinococcus granulosus single minded 2 0.0036 0.0188 0.0183
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0354 0.287 0.3442
Entamoeba histolytica disulphide oxidoreductase, putative 0.0128 0.0961 0.1399
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0124 0.0929 0.0925
Onchocerca volvulus 0.0016 0.0017 0.0015
Plasmodium vivax alpha/beta hydrolase, putative 0.0067 0.0443 0.0495
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0033 0.0028
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0213 0.025
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0215 0.0211
Echinococcus granulosus sodium channel protein 0.0056 0.0351 0.0346
Loa Loa (eye worm) hypothetical protein 0.0104 0.0757 0.0903
Onchocerca volvulus 0.0027 0.0107 0.0126
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0046 0.0041
Trypanosoma brucei heat shock protein, putative 0.0039 0.0213 0.025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Onchocerca volvulus 0.0019 0.0039 0.0042
Onchocerca volvulus 0.0045 0.0262 0.0317
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.003 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0143 0.0177
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0029 0.0125 0.0168
Leishmania major metacaspase, putative 0.0136 0.1028 0.1229
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0607 0.5015 0.602
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0481 0.395 0.474
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0037 0.0005
Entamoeba histolytica deoxycytidyl transferase, putative 0.0069 0.0465 0.064
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.012 0.0893 0.1366
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0143 0.0177
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0039 0.0213 0.0305
Mycobacterium ulcerans carboxylesterase, LipT 0.0027 0.0107 0.014
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0058 0.0053
Leishmania major trypanothione reductase 0.0999 0.8328 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0039 0.0042
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0774 0.6426 0.7943
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0324 0.0383
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0128 0.0961 0.0957
Brugia malayi larval opioid receptor 0.0045 0.0262 0.0308
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0056 0.0351 0.0346
Onchocerca volvulus 0.0045 0.0262 0.0317
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0046 0.0056
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0129 0.015
Onchocerca volvulus 0.0023 0.0075 0.0087
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0039 0.0213 0.0257
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.0213 0.025
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.003 0.0139 0.016
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0189 0.0268
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0123 0.092 0.0916
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0162 0.1251 0.2438
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0139 0.0134
Echinococcus multilocularis transient receptor potential cation channel 0.0015 0.0005 0.000000051483
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0248 0.1981 0.2362
Schistosoma mansoni ferritin 0.0025 0.0091 0.0086
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0023 0.0021
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0023 0.0018
Plasmodium falciparum exported lipase 2 0.0067 0.0443 0.0495
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0035 0.0179 0.0174
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0039 0.0213 0.025
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0046 0.0057
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0128 0.0961 0.1149
Echinococcus multilocularis heat shock protein 90 0.0039 0.0213 0.0208
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0128 0.0961 0.1473
Brugia malayi CXXC zinc finger family protein 0.0084 0.0592 0.0705
Plasmodium falciparum DNA repair protein REV1, putative 0.0021 0.0062 0.0036
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0189 0.0221
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0151 0.116 0.1156
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0128 0.0961 0.1149
Mycobacterium ulcerans hypothetical protein 0.0066 0.0436 0.0653
Loa Loa (eye worm) voltage-dependent calcium channel 0.0083 0.0586 0.0698
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0945 0.7868 0.7867
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0128 0.0961 0.1188
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0215 0.0253
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0025 0.0091 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.021 0.026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0033
Onchocerca volvulus 0.0045 0.0262 0.0317
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.0122
Entamoeba histolytica DNA topoisomerase III, putative 0.0041 0.0225 0.0273
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0035 0.0179 0.0174
Echinococcus multilocularis lamin dm0 0.0051 0.0315 0.031
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0029 0.0125 0.0144
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0213 0.025
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0138 0.0159
Trypanosoma brucei chrX additional, unordered contigs 0.0021 0.0062 0.0069
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0046 0.005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0262 0.0257
Schistosoma mansoni neuropeptide receptor 0.0045 0.0262 0.0257
Echinococcus granulosus somatostatin receptor 0.0045 0.0262 0.0257
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0607 0.5015 0.602
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0029 0.0125 0.0168
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Brugia malayi G-protein coupled receptor 0.0045 0.0262 0.0308
Echinococcus granulosus caspase 0.0359 0.2913 0.2909
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0116 0.0865 0.1033
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0774 0.6426 0.9754
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0039 0.0041
Echinococcus granulosus neuropeptides capa receptor 0.0045 0.0262 0.0257
Brugia malayi RE15519p 0.0045 0.0262 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0042 0.0052
Trichomonas vaginalis receptor histidine kinase, putative 0.0039 0.0213 0.0263
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0324 0.04
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0104 0.0761 0.0908
Mycobacterium ulcerans monoxygenase 0.0128 0.0961 0.1473
Loa Loa (eye worm) hypothetical protein 0.004 0.0215 0.0253
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0046 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0215 0.0253
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0481 0.395 0.474
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.003 0.003
Brugia malayi G protein-coupled receptor F59B2.13 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.0023 0.0074 0.0083
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0128 0.0961 0.1149
Mycobacterium ulcerans DNA polymerase IV 0.012 0.0892 0.1365
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0481 0.395 0.4722
Loa Loa (eye worm) hypothetical protein 0.003 0.0139 0.016
Brugia malayi Flap endonuclease-1 0.003 0.0138 0.0159
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0039 0.0034
Onchocerca volvulus 0.0106 0.0774 0.0951
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0029 0.0125 0.0168
Leishmania major hypothetical protein, conserved 0.0128 0.0961 0.1149
Schistosoma mansoni biogenic amine receptor 0.0045 0.0262 0.0257
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.032 0.0315
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0138 0.0159
Trypanosoma brucei Metacaspase-4 0.0136 0.1028 0.1229
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0124 0.0929 0.111
Loa Loa (eye worm) carboxylesterase 0.0027 0.0107 0.0122
Echinococcus granulosus neuroligin 0.0027 0.0107 0.0102
Schistosoma mansoni aldehyde dehydrogenase 0.0056 0.0351 0.0346
Plasmodium vivax unspecified product 0.0793 0.6586 0.7901
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0039 0.0213 0.0263
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0046 0.005
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0039 0.0041
Plasmodium vivax PST-A protein 0.0067 0.0443 0.0495
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0018 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0069 0.0462 0.0549
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0404 0.3294 0.4072
Loa Loa (eye worm) hypothetical protein 0.0158 0.1216 0.1456
Brugia malayi hypothetical protein 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.0039 0.0213 0.025
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0045 0.0262 0.0257
Loa Loa (eye worm) histone methyltransferase 0.003 0.0139 0.0161
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0082 0.0571 0.0666
Brugia malayi hypoxia-induced factor 1 0.0138 0.1047 0.1252
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0039 0.0213 0.025
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0052 0.0324 0.0383
Echinococcus multilocularis caspase 8 0.0136 0.1028 0.1023
Trypanosoma brucei DNA damage repair protein, putative 0.0021 0.0062 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0793 0.6586 0.8142
Loa Loa (eye worm) hypothetical protein 0.0021 0.0056 0.0061
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0215 0.0211
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.052 0.0587
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0067 0.0443 0.0527
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0042 0.0052
Echinococcus granulosus lamin dm0 0.0051 0.0315 0.031
Onchocerca volvulus Cell death protein 3 homolog 0.0262 0.2096 0.2586
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0027 0.0107 0.0102
Brugia malayi MGC79044 protein 0.0067 0.0443 0.0527
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0128 0.0961 0.1188
Trichomonas vaginalis glutamate synthase, putative 0.0128 0.0961 0.1188
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0236 0.0278
Schistosoma mansoni transient receptor potential channel 0.0015 0.0005 0.000000051483
Brugia malayi STAT protein, DNA binding domain containing protein 0.012 0.0899 0.1074
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.1089 0.1302
Loa Loa (eye worm) hypothetical protein 0.037 0.3006 0.3605
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0015
Loa Loa (eye worm) norepinephrine transporter 0.0106 0.0774 0.0924
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0039 0.0034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Loa Loa (eye worm) carboxylesterase 0.0158 0.1216 0.1456
Trypanosoma brucei DNA polymerase IV, putative 0.012 0.0892 0.1066
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0045 0.0262 0.0308
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0287 0.2311 0.2771
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0039 0.0213 0.0235
Mycobacterium tuberculosis Possible two component sensor kinase 0.0039 0.0213 0.0235
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0049 0.0292 0.0345
Echinococcus granulosus intermediate filament protein 0.0051 0.0315 0.031
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0128 0.0961 0.1149
Brugia malayi glutathione reductase 0.0999 0.8328 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.4849 0.5995
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0236 0.0245
Echinococcus multilocularis somatostatin receptor 0.0045 0.0262 0.0257
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0892 0.1066
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0052 0.0324 0.0319
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0128 0.0961 0.1149
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.021 0.026
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0215 0.0211
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0151 0.116 0.1388
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0052
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0189 0.0221
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0754 0.6251 0.7504
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0189 0.0184
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0052
Toxoplasma gondii protein c14orf29, putative 0.0067 0.0443 0.0527
Leishmania major DNA polymerase kappa, putative 0.0021 0.0062 0.0069
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0509 0.4185 0.517
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase-like protein, putative 0.0019 0.0042 0.0045
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0481 0.395 0.474
Brugia malayi intermediate filament protein 0.0051 0.0315 0.0372
Echinococcus granulosus allatostatin A receptor 0.0045 0.0262 0.0257
Wolbachia endosymbiont of Brugia malayi phosphoglyceromutase 0.0116 0.0865 0.2006
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0029 0.0125 0.0168
Brugia malayi Carboxylesterase family protein 0.0027 0.0107 0.0122
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0128 0.0961 0.1119
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Brugia malayi jmjC domain containing protein 0.003 0.0139 0.016
Echinococcus granulosus folate receptor beta 0.0119 0.0889 0.0885
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0262 0.0257
Echinococcus multilocularis fmrfamide receptor 0.0045 0.0262 0.0257
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0039 0.0213 0.0263
Brugia malayi hypothetical protein 0.0045 0.0262 0.0308
Brugia malayi Melatonin receptor type 1A 0.0045 0.0262 0.0308
Trypanosoma brucei metacaspase MCA3 0.0136 0.1028 0.1229
Trypanosoma brucei monoglyceride lipase, putative 0.0774 0.6426 0.7715
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.1089 0.1084
Entamoeba histolytica hypothetical protein 0.0075 0.0514 0.0715
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0058 0.0053
Treponema pallidum exodeoxyribonuclease (exoA) 0.0055 0.0346 0.0537
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0892 0.1066
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0021 0.0062 0.0069
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0069 0.0465 0.046
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0046 0.005
Schistosoma mansoni amine GPCR 0.0045 0.0262 0.0257
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0139 0.016
Brugia malayi putative neuropeptide receptor NPR1 0.0045 0.0262 0.0308
Loa Loa (eye worm) hypothetical protein 0.004 0.0215 0.0253
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0047 0.0276 0.0325
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0481 0.395 0.3947
Loa Loa (eye worm) carboxylesterase 0.0027 0.0107 0.0122
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.005
Mycobacterium ulcerans glutamate synthase subunit beta 0.0128 0.0961 0.1473
Echinococcus granulosus serotonin receptor 0.0045 0.0262 0.0257
Mycobacterium ulcerans hydrolase 0.0067 0.0443 0.0665
Echinococcus granulosus ferritin 0.0025 0.0091 0.0086
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0058 0.0053
Echinococcus multilocularis neuropeptide s receptor 0.097 0.8082 0.8081
Onchocerca volvulus 0.0041 0.0225 0.0272
Brugia malayi nuclear receptor RXR 0.0019 0.0039 0.0041
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0039 0.0213 0.0235
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0039 0.0213 0.0305
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0047 0.0276 0.0325
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0027 0.0107 0.0102
Echinococcus granulosus Polycystic kidney disease protein 0.0023 0.0075 0.007
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0067 0.0443 0.0439
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0029 0.0125 0.0168
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0055 0.0346 0.0396
Leishmania major adenylate cyclase-like protein 0.0016 0.0017 0.0015
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0215 0.0211
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0046 0.0041
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0115 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0052
Trypanosoma brucei hypothetical protein, conserved 0.0128 0.0961 0.1149
Mycobacterium tuberculosis Probable reductase 0.0248 0.1981 0.2362
Brugia malayi Doublecortin family protein 0.0023 0.0075 0.0085
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0039 0.0213 0.0305
Echinococcus multilocularis caspase 2 0.0262 0.2096 0.2092
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0256 0.2042 0.2448
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0019 0.0042 0.0045
Schistosoma mansoni microtubule-associated protein tau 0.068 0.563 0.5627
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0055 0.0346 0.041
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0056 0.0351 0.0346
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0929 0.0925
Plasmodium vivax DNA repair protein REV1, putative 0.0021 0.0062 0.0036
Schistosoma mansoni loxhd1 0.0023 0.0075 0.007
Loa Loa (eye worm) solute carrier family 6 member 4 0.0106 0.0774 0.0924
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0029 0.0125 0.0129
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0046 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0215 0.0253
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0028 0.0115 0.0152
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0039 0.0213 0.0316
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0029 0.0125 0.0144
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0039 0.0213 0.0235
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0183 0.1426 0.1422
Entamoeba histolytica Flap nuclease, putative 0.003 0.0138 0.014
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0056 0.006
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0019 0.0046 0.0041
Echinococcus granulosus flap endonuclease 1 0.003 0.0138 0.0133
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0049 0.0292 0.0287
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0106 0.0774 0.077
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0018 0.0033 0.0028
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0481 0.395 1
Entamoeba histolytica ;Alias 0.0067 0.0443 0.0607
Trichomonas vaginalis ap endonuclease, putative 0.0055 0.0346 0.0428
Brugia malayi hypothetical protein 0.0045 0.0262 0.0308
Echinococcus granulosus phd:f box containing protein 0.003 0.0139 0.0134
Entamoeba histolytica acyl-coA synthetase, putative 0.0028 0.0115 0.0105
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0041
Brugia malayi polk-prov protein 0.0072 0.049 0.0582
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0443 0.0548
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0793 0.6586 1
Plasmodium vivax SET domain protein, putative 0.0124 0.0929 0.1081
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0029 0.0125 0.0129
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0136 0.1028 0.1229
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0033 0.0033
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0439 0.3595 0.4314
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0033 0.0028
Onchocerca volvulus 0.002 0.0048 0.0053
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0045 0.0262 0.0257
Brugia malayi Endoplasmin precursor 0.0039 0.0213 0.025
Schistosoma mansoni caspase-7 (C14 family) 0.0262 0.2096 0.2092
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0069 0.0465 0.0552
Entamoeba histolytica thioredoxin reductase, putative 0.0128 0.0961 0.1399
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0039 0.0213 0.0305
Mycobacterium ulcerans hypothetical protein 0.032 0.2585 0.4007
Brugia malayi nuclear hormone receptor 0.004 0.0215 0.0253
Plasmodium falciparum epoxide hydrolase 2 0.0067 0.0443 0.0495
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0136 0.1028 0.1271
Loa Loa (eye worm) hypothetical protein 0.004 0.0215 0.0253
Plasmodium vivax hypothetical protein, conserved 0.0067 0.0443 0.0495
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0713 0.5907 0.7091
Echinococcus multilocularis glutamate synthase 0.0128 0.0961 0.0957
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Echinococcus multilocularis neuropeptide receptor 0.0045 0.0262 0.0257
Plasmodium falciparum heat shock protein 90 0.0039 0.0213 0.0217
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0128 0.0961 0.1149
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0248 0.1981 0.2362
Treponema pallidum sodium- and chloride- dependent transporter 0.0106 0.0774 0.1436
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0136 0.1028 0.1271
Schistosoma mansoni biogenic amine receptor 0.0045 0.0262 0.0257
Toxoplasma gondii hypothetical protein 0.0067 0.0443 0.0527
Loa Loa (eye worm) STAT protein 0.012 0.0899 0.1074
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0029 0.0125 0.0168
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0033 0.0028
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0128 0.0961 0.1149
Leishmania major Bem46-like serine peptidase,Serine peptidase, Clan SC, Family S09X 0.0067 0.0443 0.0527
Loa Loa (eye worm) G-protein coupled receptor 0.0045 0.0262 0.0308
Schistosoma mansoni DNA polymerase IV / kappa 0.0021 0.0062 0.0057
Loa Loa (eye worm) hypothetical protein 0.0067 0.0443 0.0527
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0041 0.0225 0.0347
Brugia malayi hypothetical protein 0.0016 0.0017 0.0015
Brugia malayi nuclear hormone receptor 0.0019 0.0039 0.0041
Echinococcus granulosus abhydrolase domain containing 3 0.0067 0.0443 0.0439
Echinococcus granulosus dna polymerase kappa 0.012 0.0892 0.0887
Loa Loa (eye worm) hypothetical protein 0.0527 0.434 0.5208
Trypanosoma cruzi hypothetical protein, conserved 0.0128 0.0961 0.1149
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0012
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0215 0.0211
Onchocerca volvulus 0.0045 0.0262 0.0317
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0262 0.0257
Plasmodium vivax DNA topoisomerase II, putative 0.0754 0.6251 0.7496
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0774 0.6426 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0168 0.0208
Leishmania major cytochrome p450-like protein 0.0056 0.0352 0.0417
Schistosoma mansoni cpg binding protein 0.0089 0.0632 0.0627
Chlamydia trachomatis endonuclease IV 0.0076 0.052 0.1243
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0207 0.0273
Onchocerca volvulus 0.0016 0.0017 0.0015
Echinococcus multilocularis transfer RNA-Lys 0.0033 0.016 0.0155
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0128 0.0961 0.1149
Trypanosoma cruzi trypanothione reductase, putative 0.0481 0.395 0.474
Loa Loa (eye worm) TOPoisomerase family member 0.0754 0.6251 0.7504
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0015
Leishmania major hypothetical protein, conserved 0.0067 0.0443 0.0527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.003 0.0037
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0033 0.0033
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0027 0.0107 0.0102
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0046 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0233 0.0288
Trypanosoma brucei metacaspase MCA2 0.0136 0.1028 0.1229
Loa Loa (eye worm) hypothetical protein 0.0136 0.1028 0.1229
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0262 0.0257
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0046 0.0016
Chlamydia trachomatis DNA topoisomerase I 0.0041 0.0225 0.049
Schistosoma mansoni hypothetical protein 0.0045 0.0262 0.0257
Schistosoma mansoni lamin 0.0051 0.0315 0.031
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0774 0.6426 0.7943
Schistosoma mansoni ferritin 0.0025 0.0091 0.0086
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0067 0.0443 0.0527
Loa Loa (eye worm) hypothetical protein 0.0028 0.0115 0.0132
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0045 0.0262 0.0257
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0039 0.0213 0.0235
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0128 0.0961 0.1136
Loa Loa (eye worm) inositol-1 0.0036 0.0189 0.0221
Trypanosoma cruzi DNA topoisomerase III, putative 0.0041 0.0225 0.0264
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0115 0.0132
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0029 0.0125 0.0129
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0055 0.0346 0.041
Schistosoma mansoni jumonji/arid domain-containing protein 0.0119 0.0887 0.0882
Trypanosoma cruzi Heat shock protein 83, putative 0.0039 0.0213 0.025
Mycobacterium tuberculosis Probable oxidoreductase 0.0602 0.4969 0.5959
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0029 0.0125 0.0129
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0136 0.1028 0.1271
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0136 0.1028 0.1271
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0846 0.703 0.8441
Schistosoma mansoni ferritin 0.0025 0.0091 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0129 0.015
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0046 0.0049
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0046 0.0041
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0029 0.0125 0.0168
Trichomonas vaginalis DNA polymerase eta, putative 0.012 0.0892 0.1103
Schistosoma mansoni apoferritin-2 0.0025 0.0091 0.0086
Treponema pallidum thioredoxin reductase (trxB) 0.0128 0.0961 0.1829
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0049 0.0038
Mycobacterium tuberculosis Conserved hypothetical protein 0.0069 0.0465 0.0538
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0027 0.0107 0.0108
Brugia malayi Probable DNA topoisomerase II 0.0754 0.6251 0.7504
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0137 0.1043 0.1038
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0046 0.0041
Toxoplasma gondii target of rapamycin (TOR), putative 0.0039 0.021 0.0247
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.019 0.149 0.2299
Echinococcus granulosus sodium and chloride dependent glycine 0.0018 0.0033 0.0028
Echinococcus granulosus muscleblind protein 0.03 0.242 0.2417
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0128 0.0961 0.1136
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.009 0.0085
Brugia malayi Thioredoxin reductase 0.0999 0.8328 1
Plasmodium vivax hypothetical protein, conserved 0.0136 0.1028 0.12
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0055 0.0346 0.0459
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0129 0.015
Schistosoma mansoni phd/f-box containing protein 0.003 0.0139 0.0134
Plasmodium falciparum esterase, putative 0.0793 0.6586 0.7901
Loa Loa (eye worm) hypothetical protein 0.004 0.0215 0.0253
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0262 0.0257
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0774 0.6426 0.7943
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0029 0.0125 0.0129
Loa Loa (eye worm) acetyltransferase 0.0143 0.1089 0.1302
Toxoplasma gondii hypothetical protein 0.0119 0.0889 0.1063
Echinococcus multilocularis lysine specific demethylase 5A 0.0114 0.0846 0.0842
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0045 0.0262 0.0257
Brugia malayi hypothetical protein 0.0045 0.0262 0.0308
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0215 0.0253
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0029 0.0125 0.0168
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0023 0.0074 0.0069
Leishmania major heat shock protein 83-1 0.0039 0.0213 0.025
Echinococcus multilocularis geminin 0.0322 0.2604 0.2601
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0129 0.0117
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0058 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.0571 0.068
Mycobacterium leprae putative cytochrome p450 0.0029 0.0125 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.4849 0.5995
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0052 0.0324 0.0383
Loa Loa (eye worm) hypothetical protein 0.003 0.0139 0.016
Schistosoma mansoni nuclear hormone receptor 0.004 0.0215 0.0211
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.0122
Onchocerca volvulus 0.0016 0.0017 0.0015
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0055 0.0346 0.0342
Loa Loa (eye worm) CXXC zinc finger family protein 0.0084 0.0592 0.0705
Brugia malayi AKH receptor 0.0045 0.0262 0.0308
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.003 0.003
Trichomonas vaginalis apoptosis inducing factor, putative 0.0128 0.0961 0.1188
Leishmania major cytochrome p450-like protein 0.0029 0.0125 0.0144
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.0213 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0042 0.0052
Plasmodium falciparum alpha/beta hydrolase, putative 0.0067 0.0443 0.0495
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0128 0.0961 0.1188
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0056 0.0351 0.0402
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0019 0.0046 0.0041
Echinococcus multilocularis Polycystic kidney disease protein 0.0023 0.0075 0.007
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0115 0.0132
Mycobacterium ulcerans two component regulator - sensor kinase 0.0039 0.0213 0.0305
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0106 0.0774 0.0924
Mycobacterium ulcerans hypothetical protein 0.0128 0.0961 0.1473
Echinococcus multilocularis voltage dependent calcium channel 0.0142 0.108 0.1076
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0037 0.0032
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0039 0.0034
Leishmania major hypothetical protein, conserved 0.003 0.0139 0.016
Echinococcus granulosus G protein coupled receptor 139 0.0045 0.0262 0.0257
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0115 0.0132
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0096 0.0091
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0067 0.0443 0.0527
Echinococcus granulosus death domain containing protein 0.0017 0.0023 0.0018
Echinococcus multilocularis neuroligin 0.0027 0.0107 0.0102
Echinococcus granulosus biogenic amine 5HT receptor 0.0045 0.0262 0.0257
Echinococcus multilocularis ferritin 0.0025 0.0091 0.0086
Brugia malayi Tachykinin-like peptides receptor 99D 0.0045 0.0262 0.0308
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0129 0.0117
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0037 0.0038
Schistosoma mansoni alpha-1 adrenergic receptor 0.0045 0.0262 0.0257
Schistosoma mansoni sulfide quinone reductase 0.0128 0.0961 0.0957
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0128 0.0961 0.1188
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0047 0.0276 0.0325
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0262 0.0257
Schistosoma mansoni neuropeptide F-like receptor 0.0045 0.0262 0.0257
Schistosoma mansoni ferritin 0.0025 0.0091 0.0086
Brugia malayi Carboxylesterase family protein 0.0158 0.1216 0.1456
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.4849 0.5995
Trypanosoma cruzi DNA polymerase eta, putative 0.0069 0.0465 0.0552
Echinococcus granulosus tumor protein p63 0.1036 0.8639 0.8639
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0213 0.0217
Brugia malayi tailless protein 0.0019 0.0039 0.0041
Trypanosoma brucei metacaspase 0.0136 0.1028 0.1229
Mycobacterium ulcerans putative regultory protein 0.0039 0.0213 0.0305
Trypanosoma brucei heat shock protein, putative 0.0039 0.0213 0.025
Echinococcus multilocularis rho GTPase activating protein 20 0.0041 0.0225 0.022
Loa Loa (eye worm) globin family protein 0.0016 0.0017 0.0015
Toxoplasma gondii hypothetical protein 0.0018 0.0033 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0259 0.032
Echinococcus granulosus neuropeptide receptor A26 0.097 0.8082 0.8081
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0354 0.287 0.3442
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0055 0.0346 0.0513
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0037 0.0032
Toxoplasma gondii hypothetical protein 0.0069 0.0462 0.0549
Echinococcus multilocularis caspase 0.0359 0.2913 0.2909
Trichomonas vaginalis mercuric reductase, putative 0.0481 0.395 0.4882
Loa Loa (eye worm) hypothetical protein 0.0106 0.0774 0.0924
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0607 0.5015 0.602
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0215 0.0211
Echinococcus multilocularis neuropeptide FF receptor 2 0.0045 0.0262 0.0257
Leishmania major protein kinase, putative 0.0017 0.0023 0.0022
Brugia malayi hypothetical protein 0.0045 0.0262 0.0308
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0039 0.0034
Echinococcus granulosus JmjC domain containing protein 4 0.003 0.0139 0.0134
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0128 0.0961 0.1399
Trichomonas vaginalis ap endonuclease, putative 0.0055 0.0346 0.0428
Trypanosoma brucei unspecified product 0.0048 0.0284 0.0335
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0308
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0481 0.395 0.474
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0248 0.1981 0.2362
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0037 0.0032
Plasmodium falciparum thioredoxin reductase 0.0481 0.395 0.4722
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0443 0.0548
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0142 0.108 0.1076
Brugia malayi Protein kinase domain containing protein 0.0017 0.0026 0.0026
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0039 0.0041
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0215 0.0211
Loa Loa (eye worm) hypothetical protein 0.004 0.0215 0.0253

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

69 literature references were collected for this gene.

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