Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0217 | 0.0164 |
Leishmania major | zeta tubulin, putative | 0.0053 | 0.1487 | 0.1902 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.005 | 0.005 |
Schistosoma mansoni | alpha tubulin | 0.0169 | 0.5517 | 0.5517 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Trypanosoma brucei | zeta tubulin, putative | 0.0053 | 0.1487 | 0.1902 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.5355 | 0.5355 |
Brugia malayi | Tubulin beta chain | 0.0053 | 0.1487 | 0.2009 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0217 | 0.0164 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Trichomonas vaginalis | tubulin beta-1 chain, putative | 0.0053 | 0.1487 | 0.1954 |
Schistosoma mansoni | tubulin subunit alpha | 0.0169 | 0.5517 | 0.5517 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0169 | 0.5517 | 0.5517 |
Schistosoma mansoni | alpha tubulin | 0.0169 | 0.5517 | 0.5517 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.1255 | 0.1695 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.1203 | 0.1203 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0169 | 0.5517 | 0.7437 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.1203 | 0.1203 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0169 | 0.5517 | 0.7437 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0217 | 0.0164 |
Echinococcus multilocularis | tubulin subunit TubB | 0.0169 | 0.5517 | 0.5517 |
Brugia malayi | glutathione reductase | 0.0046 | 0.1255 | 0.1695 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0223 | 0.7402 | 0.7402 |
Echinococcus multilocularis | tubulin alpha | 0.0121 | 0.3858 | 0.3858 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0169 | 0.5517 | 0.5517 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0978 | 0.1262 |
Trypanosoma cruzi | tubulin gamma chain | 0.0121 | 0.3858 | 0.5148 |
Echinococcus multilocularis | beta tubulin | 0.0223 | 0.7402 | 0.7402 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.1255 | 0.1638 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0105 | 0.3288 | 0.8837 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.1255 | 0.1255 |
Schistosoma mansoni | chromobox protein | 0.0011 | 0.005 | 0.005 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Giardia lamblia | Epsilon tubulin | 0.0053 | 0.1487 | 0.2009 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0068 | 0.2038 | 0.2704 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.1255 | 0.1638 |
Echinococcus multilocularis | tubulin subunit beta | 0.0223 | 0.7402 | 0.7402 |
Toxoplasma gondii | alpha tubulin TUBA1 | 0.0169 | 0.5517 | 0.7454 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0023 | 0.0473 | 0.0575 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0053 | 0.1487 | 0.1954 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0217 | 0.0227 |
Giardia lamblia | Gamma tubulin | 0.0121 | 0.3858 | 0.5212 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0169 | 0.5517 | 0.7437 |
Plasmodium falciparum | alpha tubulin 2 | 0.0169 | 0.5517 | 0.7454 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.1255 | 0.1695 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0635 | 0.0635 |
Toxoplasma gondii | 'chromo' (CHRromatin Organization MOdifier) domain-containing protein | 0.0011 | 0.005 | 0.0068 |
Brugia malayi | tubulin alpha chain - mouse | 0.0169 | 0.5517 | 0.7454 |
Schistosoma mansoni | tubulin subunit beta | 0.0053 | 0.1487 | 0.1487 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.0169 | 0.5517 | 0.5517 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0217 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.005 | 0.005 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0452 | 0.0485 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.002 | 0.0375 | 0.0507 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0217 | 0.0164 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0452 | 0.0547 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0011 | 0.005 | 0.0068 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0169 | 0.5517 | 0.7437 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.005 | 0.005 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0169 | 0.5517 | 0.5517 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0695 | 0.0695 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0121 | 0.3858 | 0.5179 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0596 | 0.0742 |
Schistosoma mansoni | tubulin subunit beta | 0.0223 | 0.7402 | 0.7402 |
Echinococcus multilocularis | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.005 | 0.005 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0635 | 0.0858 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.1203 | 0.1625 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0223 | 0.7402 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0105 | 0.3288 | 0.8837 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0299 | 1 | 1 |
Plasmodium vivax | tubulin epsilon chain, putative | 0.0121 | 0.3858 | 0.5179 |
Loa Loa (eye worm) | tubulin gamma chain | 0.0121 | 0.3858 | 0.3858 |
Schistosoma mansoni | chromobox protein | 0.0011 | 0.005 | 0.005 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0596 | 0.0742 |
Trypanosoma brucei | epsilon tubulin | 0.0121 | 0.3858 | 0.5148 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0169 | 0.5517 | 0.7437 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0012 | 0.0098 | 0.0065 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0016 | 0.0217 | 0.0164 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.1255 | 0.1255 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0016 | 0.0217 | 0.0227 |
Brugia malayi | Protein cec-1. | 0.0011 | 0.005 | 0.0068 |
Trypanosoma brucei | beta tubulin | 0.0223 | 0.7402 | 1 |
Brugia malayi | Tubulin alpha-2 chain | 0.0169 | 0.5517 | 0.7454 |
Schistosoma mansoni | tubulin subunit beta | 0.0223 | 0.7402 | 0.7402 |
Trypanosoma brucei | zeta tubulin | 0.0053 | 0.1487 | 0.1902 |
Echinococcus multilocularis | chromobox protein 2 | 0.0011 | 0.005 | 0.005 |
Giardia lamblia | Alpha-tubulin | 0.0169 | 0.5517 | 0.7454 |
Echinococcus granulosus | tubulin beta 1 chain | 0.0223 | 0.7402 | 0.7402 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0978 | 0.1322 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0217 | 0.0294 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0121 | 0.3858 | 0.5179 |
Echinococcus granulosus | Chromo domain | 0.0011 | 0.005 | 0.005 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0635 | 0.0635 |
Toxoplasma gondii | alpha-tubulin I, putative | 0.0169 | 0.5517 | 0.7454 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0452 | 0.0485 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0217 | 0.0164 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0223 | 0.7402 | 0.7402 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0011 | 0.005 | 0.005 |
Trypanosoma brucei | tubulin delta chain | 0.0053 | 0.1487 | 0.1902 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0053 | 0.1487 | 0.1954 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.005 | 0.005 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0011 | 0.005 | 0.005 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.2006 | 0.2006 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0016 | 0.0217 | 0.5 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0217 | 0.0294 |
Trypanosoma brucei | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Plasmodium vivax | delta tubulin, putative | 0.0053 | 0.1487 | 0.1954 |
Echinococcus granulosus | peroxisome assembly protein 26 | 0.0169 | 0.5517 | 0.5517 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0116 | 0.3698 | 0.3698 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Loa Loa (eye worm) | helicase | 0.0011 | 0.005 | 0.005 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Echinococcus multilocularis | geminin | 0.0164 | 0.5355 | 0.5355 |
Echinococcus multilocularis | peroxisome assembly protein 26 | 0.0169 | 0.5517 | 0.5517 |
Schistosoma mansoni | tubulin subunit beta | 0.0223 | 0.7402 | 0.7402 |
Echinococcus multilocularis | Chromo domain | 0.0011 | 0.005 | 0.005 |
Trypanosoma brucei | beta tubulin | 0.0223 | 0.7402 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0011 | 0.005 | 0.00000000018656 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.2006 | 0.2006 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.3675 | 0.3675 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0217 | 0.0217 |
Brugia malayi | Tubulin gamma chain | 0.0121 | 0.3858 | 0.5212 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0023 | 0.0473 | 0.0575 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0223 | 0.7402 | 0.7402 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Brugia malayi | Tubulin alpha chain | 0.0053 | 0.1487 | 0.2009 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.005 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.005 | 0.005 |
Loa Loa (eye worm) | tubulin beta-4 chain | 0.0223 | 0.7402 | 0.7402 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0452 | 0.0547 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0011 | 0.005 | 0.005 |
Trypanosoma brucei | epsilon tubulin | 0.0121 | 0.3858 | 0.5148 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Brugia malayi | Tubulin beta chain | 0.0068 | 0.2038 | 0.2754 |
Trypanosoma brucei | beta tubulin | 0.0223 | 0.7402 | 1 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0169 | 0.5517 | 0.5517 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.1078 | 0.1398 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0169 | 0.5517 | 0.5517 |
Echinococcus multilocularis | tubulin delta chain | 0.0053 | 0.1487 | 0.1487 |
Echinococcus granulosus | tubulin gamma 1 chain | 0.0121 | 0.3858 | 0.3858 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0223 | 0.7402 | 0.7402 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.005 | 0.005 |
Trypanosoma brucei | beta tubulin | 0.0223 | 0.7402 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0053 | 0.1487 | 0.2009 |
Brugia malayi | hypothetical protein | 0.0011 | 0.005 | 0.0068 |
Giardia lamblia | Alpha-tubulin | 0.0169 | 0.5517 | 0.7454 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0011 | 0.005 | 0.0068 |
Brugia malayi | alpha-tubulin | 0.0169 | 0.5517 | 0.7454 |
Loa Loa (eye worm) | alpha-tubulin | 0.0169 | 0.5517 | 0.5517 |
Trypanosoma cruzi | tubulin delta chain | 0.0053 | 0.1487 | 0.1902 |
Echinococcus multilocularis | bloom syndrome protein | 0.0023 | 0.0473 | 0.0473 |
Echinococcus granulosus | tubulin beta 4A class IVa | 0.0223 | 0.7402 | 0.7402 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0068 | 0.2038 | 0.2704 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0978 | 0.1262 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0635 | 0.0796 |
Loa Loa (eye worm) | tubulin beta-1 chain | 0.0223 | 0.7402 | 0.7402 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.1255 | 0.1255 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.3723 | 0.3723 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0223 | 0.7402 | 0.7402 |
Brugia malayi | Tubulin alpha-2 chain | 0.0169 | 0.5517 | 0.7454 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.2006 | 0.2006 |
Echinococcus multilocularis | beta tubulin | 0.0223 | 0.7402 | 0.7402 |
Echinococcus granulosus | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Loa Loa (eye worm) | BEN-1 protein | 0.0223 | 0.7402 | 0.7402 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0635 | 0.0635 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.1255 | 0.1584 |
Mycobacterium tuberculosis | Probable reductase | 0.0105 | 0.3288 | 0.8837 |
Onchocerca volvulus | 0.003 | 0.0695 | 0.3244 | |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0217 | 0.0227 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0217 | 0.0294 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.00000000015149 | 0.00000000020465 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0223 | 0.7402 | 0.7402 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0105 | 0.3288 | 0.8837 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0105 | 0.3288 | 0.8837 |
Giardia lamblia | Delta tubulin | 0.0053 | 0.1487 | 0.2009 |
Echinococcus granulosus | geminin | 0.0164 | 0.5355 | 0.5355 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0169 | 0.5517 | 0.5517 |
Loa Loa (eye worm) | BEN-1 protein | 0.0223 | 0.7402 | 0.7402 |
Trichomonas vaginalis | tubulin, putative | 0.0068 | 0.2038 | 0.2704 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0452 | 0.0547 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0011 | 0.005 | 0.005 |
Echinococcus granulosus | beta tubulin | 0.0223 | 0.7402 | 0.7402 |
Brugia malayi | Tubulin beta-1 chain | 0.0223 | 0.7402 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0217 | 0.0294 |
Loa Loa (eye worm) | tubulin alpha-2 chain | 0.0169 | 0.5517 | 0.5517 |
Toxoplasma gondii | 'chromo' (CHRromatin Organization MOdifier) domain-containing protein | 0.0011 | 0.005 | 0.0068 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0217 | 0.0164 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0223 | 0.7402 | 0.7402 |
Onchocerca volvulus | 0.0068 | 0.2038 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.5517 | 0.5517 |
Schistosoma mansoni | tubulin subunit beta | 0.0223 | 0.7402 | 0.7402 |
Schistosoma mansoni | tubulin subunit alpha | 0.0169 | 0.5517 | 0.5517 |
Echinococcus multilocularis | snurportin 1 | 0.0299 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.005 | 0.005 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Leishmania major | trypanothione reductase | 0.0046 | 0.1255 | 0.1584 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.1203 | 0.1203 |
Plasmodium falciparum | chromodomain-helicase-DNA-binding protein 1 homolog, putative | 0.0011 | 0.005 | 0.0068 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Echinococcus granulosus | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Toxoplasma gondii | beta-tubulin, putative | 0.0223 | 0.7402 | 1 |
Trypanosoma cruzi | alpha tubulin, putative | 0.0169 | 0.5517 | 0.742 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0053 | 0.1487 | 0.1954 |
Entamoeba histolytica | tubulin family protein | 0.0223 | 0.7402 | 1 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Schistosoma mansoni | hypothetical protein | 0.0299 | 1 | 1 |
Plasmodium vivax | tubulin gamma chain, putative | 0.0121 | 0.3858 | 0.5179 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Loa Loa (eye worm) | beta-tubulin | 0.0223 | 0.7402 | 0.7402 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.005 | 0.005 |
Leishmania major | gamma-tubulin | 0.0121 | 0.3858 | 0.5148 |
Echinococcus granulosus | beta tubulin | 0.0223 | 0.7402 | 0.7402 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0223 | 0.7402 | 0.7402 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.2006 | 0.2006 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Echinococcus granulosus | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Trichomonas vaginalis | tubulin, putative | 0.0053 | 0.1487 | 0.1954 |
Echinococcus granulosus | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Echinococcus granulosus | bloom syndrome protein | 0.0023 | 0.0473 | 0.0473 |
Echinococcus granulosus | chromobox protein 2 | 0.0011 | 0.005 | 0.005 |
Echinococcus granulosus | tubulin epsilon chain | 0.0121 | 0.3858 | 0.3858 |
Plasmodium falciparum | heterochromatin protein 1 | 0.0011 | 0.005 | 0.0068 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0101 | 0.3146 | 0.4211 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0169 | 0.5517 | 0.7437 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.005 | 0.005 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0217 | 0.0294 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.5355 | 0.5355 |
Echinococcus granulosus | alpha tubulin | 0.0169 | 0.5517 | 0.5517 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Loa Loa (eye worm) | tubulin alpha-3 chain | 0.0101 | 0.3146 | 0.3146 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0121 | 0.3858 | 0.5212 |
Schistosoma mansoni | tubulin subunit gamma | 0.0121 | 0.3858 | 0.3858 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0116 | 0.3692 | 1 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0121 | 0.3858 | 0.5179 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.1255 | 0.1695 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0012 | 0.0071 | 0.0096 |
Echinococcus multilocularis | tubulin, beta 4A class IVa | 0.0223 | 0.7402 | 0.7402 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.1203 | 0.1203 |
Entamoeba histolytica | tubulin alpha chain, putative | 0.0169 | 0.5517 | 0.7437 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0978 | 0.0978 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.3675 | 0.3675 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0053 | 0.1487 | 0.1954 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0105 | 0.3288 | 0.8168 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.1203 | 0.1203 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0635 | 0.0736 |
Echinococcus granulosus | tubulin subunit TubB | 0.0169 | 0.5517 | 0.5517 |
Brugia malayi | Tubulin alpha chain | 0.0169 | 0.5517 | 0.7454 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.1203 | 0.1203 |
Trypanosoma cruzi | beta tubulin, putative | 0.0223 | 0.7402 | 1 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0223 | 0.7402 | 1 |
Brugia malayi | Valyl-tRNA synthetase | 0.0011 | 0.005 | 0.0068 |
Echinococcus multilocularis | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Plasmodium falciparum | tubulin epsilon chain, putative | 0.0121 | 0.3858 | 0.5212 |
Plasmodium vivax | tubulin alpha chain, putative | 0.0169 | 0.5517 | 0.7437 |
Echinococcus multilocularis | hypothetical protein | 0.0169 | 0.5517 | 0.5517 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.0169 | 0.5517 | 0.5517 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0217 | 0.0164 |
Mycobacterium tuberculosis | Cell division protein FtsZ | 0.0053 | 0.1487 | 0.3654 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.1255 | 0.2985 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0116 | 0.3692 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0011 | 0.005 | 0.0068 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0223 | 0.7402 | 0.7402 |
Echinococcus multilocularis | tubulin epsilon chain | 0.0121 | 0.3858 | 0.3858 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0116 | 0.3698 | 0.4962 |
Schistosoma mansoni | tubulin subunit beta | 0.0223 | 0.7402 | 0.7402 |
Brugia malayi | CHD4 protein | 0.0011 | 0.005 | 0.0068 |
Entamoeba histolytica | tubulin alpha-1 chain | 0.0169 | 0.5517 | 0.7437 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.2006 | 0.2006 |
Giardia lamblia | Beta tubulin | 0.0223 | 0.7402 | 1 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0018 | 0.0304 | 0.0304 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.005 | 0.005 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0223 | 0.7402 | 0.7402 |
Plasmodium vivax | tubulin beta chain, putative | 0.0223 | 0.7402 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0978 | 0.4668 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.1078 | 0.5169 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0012 | 0.0071 | 0.0096 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0016 | 0.0217 | 0.0227 |
Brugia malayi | RNA, U transporter 1 | 0.008 | 0.242 | 0.3269 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0016 | 0.0217 | 0.0164 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0068 | 0.2038 | 0.2704 |
Echinococcus multilocularis | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Brugia malayi | beta-tubulin, identical | 0.0223 | 0.7402 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.2006 | 0.2006 |
Schistosoma mansoni | tubulin subunit alpha | 0.0053 | 0.1487 | 0.1487 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Giardia lamblia | Beta tubulin | 0.0223 | 0.7402 | 1 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.0121 | 0.3858 | 0.5148 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0169 | 0.5517 | 0.7437 |
Trichomonas vaginalis | tubulin, putative | 0.0223 | 0.7402 | 1 |
Brugia malayi | SET domain containing protein | 0.0011 | 0.005 | 0.0068 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0169 | 0.5517 | 0.7437 |
Trypanosoma brucei | alpha tubulin, putative | 0.0068 | 0.2038 | 0.2657 |
Trypanosoma brucei | beta tubulin | 0.0121 | 0.3858 | 0.5148 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0116 | 0.3692 | 1 |
Brugia malayi | Cell division protein ftsZ | 0.0053 | 0.1487 | 0.2009 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0217 | 0.0164 |
Echinococcus multilocularis | tubulin gamma 1 chain | 0.0121 | 0.3858 | 0.3858 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0452 | 0.0547 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0635 | 0.0635 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0169 | 0.5517 | 0.7437 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.1203 | 0.1203 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0011 | 0.005 | 0.005 |
Brugia malayi | tubulin alpha-2 chain | 0.0169 | 0.5517 | 0.7454 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0635 | 0.0858 |
Schistosoma mansoni | tubulin subunit beta | 0.0223 | 0.7402 | 0.7402 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0053 | 0.1487 | 0.1902 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.1255 | 0.1584 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0016 | 0.0217 | 0.0164 |
Trichomonas vaginalis | tubulin, putative | 0.0068 | 0.2038 | 0.2704 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0217 | 0.0217 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.3698 | 0.3698 |
Loa Loa (eye worm) | alpha-tubulin | 0.0169 | 0.5517 | 0.5517 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0048 | 0.1327 | 0.1327 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.0169 | 0.5517 | 0.5517 |
Trypanosoma cruzi | tubulin delta chain | 0.0053 | 0.1487 | 0.1902 |
Schistosoma mansoni | alpha tubulin | 0.0169 | 0.5517 | 0.5517 |
Entamoeba histolytica | tubulin family protein | 0.0223 | 0.7402 | 1 |
Trypanosoma brucei | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Schistosoma mansoni | tubulin subunit delta | 0.0053 | 0.1487 | 0.1487 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0169 | 0.5517 | 0.5517 |
Echinococcus granulosus | tubulin delta chain | 0.0053 | 0.1487 | 0.1487 |
Loa Loa (eye worm) | tubulin beta-2A chain | 0.0223 | 0.7402 | 0.7402 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0217 | 0.0164 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.3675 | 0.4964 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0011 | 0.005 | 0.005 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0217 | 0.0164 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0016 | 0.0217 | 0.0164 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.0121 | 0.3858 | 0.5148 |
Loa Loa (eye worm) | alpha-tubulin isotype 2 | 0.0116 | 0.3698 | 0.3698 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.1078 | 0.1398 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.3146 | 0.3146 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0116 | 0.3698 | 0.3698 |
Schistosoma mansoni | tubulin subunit epsilon | 0.0121 | 0.3858 | 0.3858 |
Loa Loa (eye worm) | RecQ helicase | 0.0023 | 0.0473 | 0.0473 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0023 | 0.0473 | 0.0639 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0016 | 0.0212 | 0.022 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0068 | 0.2038 | 0.2704 |
Toxoplasma gondii | chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 | 0.0011 | 0.005 | 0.0068 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0116 | 0.3692 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0016 | 0.0217 | 0.0164 |
Echinococcus granulosus | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Plasmodium falciparum | alpha tubulin 1 | 0.0169 | 0.5517 | 0.7454 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0206 | 0.0278 |
Leishmania major | delta tubulin, putative | 0.0053 | 0.1487 | 0.1902 |
Mycobacterium ulcerans | cell division protein FtsZ | 0.0053 | 0.1487 | 1 |
Echinococcus granulosus | Chromobox protein 3 | 0.0011 | 0.005 | 0.005 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0635 | 0.0736 |
Plasmodium falciparum | tubulin beta chain | 0.0223 | 0.7402 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0105 | 0.3288 | 0.8837 |
Treponema pallidum | cell division protein FtsZ | 0.0053 | 0.1487 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.2006 | 0.266 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.1203 | 0.1203 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0223 | 0.7402 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0217 | 0.0164 |
Loa Loa (eye worm) | tubulin beta chain | 0.0053 | 0.1487 | 0.1487 |
Echinococcus granulosus | tubulin alpha | 0.0121 | 0.3858 | 0.3858 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0016 | 0.0217 | 0.0294 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0217 | 0.0294 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Loa Loa (eye worm) | tubulin beta chain | 0.0223 | 0.7402 | 0.7402 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0217 | 0.0294 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0011 | 0.005 | 0.005 |
Trypanosoma brucei | tubulin gamma chain | 0.0121 | 0.3858 | 0.5148 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0169 | 0.5517 | 0.5517 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.2006 | 0.2006 |
Brugia malayi | M-phase phosphoprotein, mpp8 | 0.0011 | 0.005 | 0.0068 |
Leishmania major | epsilon tubulin, putative | 0.0121 | 0.3858 | 0.5148 |
Toxoplasma gondii | beta tubulin | 0.0223 | 0.7402 | 1 |
Plasmodium vivax | tubulin alpha chain, putative | 0.0169 | 0.5517 | 0.7437 |
Toxoplasma gondii | beta-1 tubulin, putative | 0.0223 | 0.7402 | 1 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Entamoeba histolytica | tubulin gamma chain | 0.0121 | 0.3858 | 0.5179 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0217 | 0.0217 |
Giardia lamblia | Beta tubulin | 0.0223 | 0.7402 | 1 |
Trypanosoma brucei | epsilon tubulin | 0.0121 | 0.3858 | 0.5148 |
Plasmodium falciparum | tubulin gamma chain | 0.0121 | 0.3858 | 0.5212 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.2006 | 0.266 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsZ | 0.0053 | 0.1487 | 1 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0068 | 0.2038 | 0.2704 |
Echinococcus multilocularis | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Schistosoma mansoni | tubulin subunit alpha | 0.0169 | 0.5517 | 0.5517 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0169 | 0.5517 | 0.5517 |
Leishmania major | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Trypanosoma brucei | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0223 | 0.7402 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0635 | 0.0858 |
Echinococcus multilocularis | tubulin beta 1 chain | 0.0223 | 0.7402 | 0.7402 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0053 | 0.1487 | 0.1902 |
Entamoeba histolytica | recQ family helicase, putative | 0.0012 | 0.0098 | 0.0065 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.1255 | 0.1255 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.1255 | 0.1695 |
Echinococcus granulosus | tubulin subunit beta | 0.0223 | 0.7402 | 0.7402 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0053 | 0.1487 | 0.2009 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0223 | 0.7402 | 1 |
Leishmania major | beta tubulin | 0.0223 | 0.7402 | 1 |
Trypanosoma brucei | alpha tubulin | 0.0169 | 0.5517 | 0.742 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0169 | 0.5517 | 0.5517 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.0169 | 0.5517 | 0.5517 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.005 | 0.00000000018656 |
Plasmodium falciparum | tubulin delta chain, putative | 0.0053 | 0.1487 | 0.2009 |
Plasmodium vivax | hypothetical protein, conserved | 0.0011 | 0.005 | 0.00000000018656 |
Echinococcus multilocularis | tubulin alpha chain | 0.0169 | 0.5517 | 0.5517 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.2006 | 0.271 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (functional) | = 180.79 uM | Concentration that reducedthe MT-4 cell viability by 50%. | ChEMBL. | 12672256 |
CC50 (functional) | = 180.79 uM | Concentration that reducedthe MT-4 cell viability by 50%. | ChEMBL. | 12672256 |
IC50 (functional) | ND 0 uM | Concentration required to inhibit the viral (HIV-1 NNRTI resistant strain) cytopathic effect by 50% in MT-4 cells. | ChEMBL. | 12672256 |
IC50 (functional) | > 180.79 uM | Concentration required to inhibit the viral (HIV-1 IIIB strain) cytopathic effect by 50% in MT-4 cells. | ChEMBL. | 12672256 |
IC50 (functional) | > 180.79 uM | Concentration required to inhibit the viral (HIV-1 NL4.3 strain) cytopathic effect by 50% in MT-4 cells. | ChEMBL. | 12672256 |
IC50 (functional) | > 180.79 uM | Concentration required to inhibit the viral (HIV-2 ROD) cytopathic effect by 50% in MT-4 cells. | ChEMBL. | 12672256 |
IC50 (functional) | > 180.79 uM | Concentration required to inhibit the viral (SIV mac251) cytopathic effect by 50% in MT-4 cells. | ChEMBL. | 12672256 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.