Detailed information for compound 562180

Basic information

Technical information
  • TDR Targets ID: 562180
  • Name: sodium (E)-3-(5-nitro-2-furyl)prop-2-enoate
  • MW: 206.108 | Formula: C7H5NNaO5
  • H donors: 0 H acceptors: 4 LogP: 1.79 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]C(=O)C=Cc1ccc(o1)[N+](=O)[O-].[NaH+]
  • InChi: 1S/C7H5NO5.Na/c9-7(10)4-2-5-1-3-6(13-5)8(11)12;/h1-4H,(H,9,10);/q;+1/p-1/b4-2+;
  • InChiKey: GXLPJVBXVYMXLM-VEELZWTKSA-M  


Substructure search Similarity search

Network

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Synonyms

  • sodium (E)-3-(5-nitro-2-furyl)-2-propenoate
  • sodium (E)-3-(5-nitrofuran-2-yl)prop-2-enoate
  • sodium (E)-3-(5-nitro-2-furyl)acrylate
  • nitrofurylacrylic acid
  • 38665-24-6
  • Sodium 5-nitrofurylacrylate
  • 2-FURANACRYLIC ACID, 5-NITRO-, SODIUM SALT
  • 2-Propenoic acid, 3-(5-nitro-2-furanyl)-, sodium salt
  • 3-(5-Nitro-2-furyl)acrylic acid sodium salt
  • 5-Nfa sodium salt
  • 5-Nitro-2-furanacrylic acid sodium salt
  • Sodium 5-nitro-2-furylacrylate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0018 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0018 0.0084 0.0084
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.003 0.0443 0.0443
Echinococcus granulosus acetylcholinesterase 0.0271 0.776 0.774
Loa Loa (eye worm) hypothetical protein 0.0018 0.0084 0.0084
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.003 0.0443 0.0443
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0023 0.0217 0.1772
Brugia malayi Matrixin family protein 0.0018 0.0084 0.0084
Mycobacterium ulcerans carboxylesterase, LipT 0.0046 0.0923 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Echinococcus granulosus inositol monophosphatase 1 0.0023 0.0217 0.0131
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.003 0.0443 0.0359
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.003 0.0443 0.0443
Brugia malayi Carboxylesterase family protein 0.0046 0.0923 0.0923
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0271 0.776 0.7741
Loa Loa (eye worm) hypothetical protein 0.0046 0.0923 0.0923
Onchocerca volvulus 0.0018 0.0088 0.0045
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0038 0.0688 0.0606
Schistosoma mansoni nAChR subunit 0.003 0.0443 0.0363
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0923 1
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.003 0.0443 0.0359
Loa Loa (eye worm) hypothetical protein 0.0018 0.0088 0.0088
Onchocerca volvulus Matrilysin homolog 0.004 0.0754 0.7985
Echinococcus multilocularis nAChR subunit 0.003 0.0443 0.0359
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0923 0.0847
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0023 0.0217 0.1772
Echinococcus granulosus acetylcholinesterase 0.0271 0.776 0.774
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Onchocerca volvulus 0.0018 0.0088 0.0045
Echinococcus granulosus sodium:glucose cotransporter 0.0038 0.0688 0.0606
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0028 0.038 0.038
Echinococcus granulosus sodium:glucose cotransporter 2 0.0038 0.0688 0.0606
Echinococcus granulosus glycine receptor subunit alpha 1 0.003 0.0443 0.0359
Loa Loa (eye worm) hypothetical protein 0.0046 0.0923 0.0923
Echinococcus granulosus neuroligin 0.0046 0.0923 0.0843
Brugia malayi Sodium:solute symporter family protein 0.0038 0.0688 0.0688
Schistosoma mansoni hypothetical protein 0.0026 0.0314 0.0232
Loa Loa (eye worm) hypothetical protein 0.0271 0.776 0.776
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.003 0.0443 0.0443
Mycobacterium tuberculosis Carboxylesterase LipT 0.0046 0.0923 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0088 0.0088
Echinococcus multilocularis glycine receptor subunit alpha 1 0.003 0.0443 0.0359
Echinococcus granulosus glycine receptor subunit beta 0.003 0.0443 0.0359
Brugia malayi hypothetical protein 0.0046 0.0923 0.0923
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0022 0.0204 0.0204
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.003 0.0443 0.0359
Loa Loa (eye worm) hypothetical protein 0.0018 0.0088 0.0088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0028 0.038 0.0295
Echinococcus granulosus glycine receptor subunit alpha 1 0.003 0.0443 0.0359
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.003 0.0443 0.0359
Brugia malayi Matrixin family protein 0.0044 0.0864 0.0864
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0023 0.0217 0.0185
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.003 0.0443 0.0443
Loa Loa (eye worm) LGC-31 protein 0.003 0.0443 0.0443
Brugia malayi Carboxylesterase family protein 0.0046 0.0923 0.0923
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0038 0.0688 0.0688
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.003 0.0443 0.0363
Loa Loa (eye worm) matrixin family protein 0.004 0.0754 0.0754
Brugia malayi Carboxylesterase family protein 0.0271 0.776 0.776
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.003 0.0443 0.0359
Plasmodium vivax ataxin-2 like protein, putative 0.0015 0 0.5
Onchocerca volvulus 0.0046 0.0923 1
Schistosoma mansoni nAChR subunit 0.003 0.0443 0.0363
Loa Loa (eye worm) inositol-1 0.0023 0.0217 0.0217
Schistosoma mansoni nAChR subunit 0.003 0.0443 0.0363
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0185 0.0102
Brugia malayi Carboxylesterase family protein 0.0046 0.0923 0.0923
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Loa Loa (eye worm) matrix metalloproteinase 0.0018 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0018 0.0088 0.0088
Echinococcus multilocularis high affinity choline transporter 1 0.0345 1 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.003 0.0443 0.0443
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0088 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0025 0.0298 0.0213
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0025 0.0298 0.0216
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0066 0.1535 0.146
Schistosoma mansoni BC026374 protein (S09 family) 0.0046 0.0923 0.0847
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.003 0.0443 0.0359
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.003 0.0443 0.0443
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0022 0.0204 0.075
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0025 0.0298 0.0213
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0025 0.0298 0.0213
Echinococcus multilocularis glycine receptor subunit beta 0.003 0.0443 0.0359
Onchocerca volvulus 0.0046 0.0923 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.003 0.0443 0.0363
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0028 0.038 0.0295
Loa Loa (eye worm) carboxylesterase 0.0046 0.0923 0.0923
Brugia malayi Carboxylesterase family protein 0.0046 0.0923 0.0923
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.003 0.0443 0.0443
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0217 1
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0185 0.0102
Onchocerca volvulus 0.003 0.0443 0.4282
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0066 0.1535 0.146
Loa Loa (eye worm) hypothetical protein 0.0018 0.0088 0.0088
Echinococcus granulosus nAChR subunit 0.003 0.0443 0.0359
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0028 0.038 0.038
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0088 0.0088
Echinococcus multilocularis BC026374 protein (S09 family) 0.0046 0.0923 0.0843
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0025 0.0298 0.0298
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.003 0.0443 0.0443
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.003 0.0443 0.0443
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0038 0.0688 1
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0038 0.0688 0.0606
Echinococcus granulosus sodium:myo inositol cotransporter 0.0038 0.0688 0.0606
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0028 0.038 0.0299
Loa Loa (eye worm) hypothetical protein 0.0251 0.7146 0.7146
Schistosoma mansoni nAChR subunit 0.003 0.0443 0.0363
Echinococcus multilocularis voltage dependent calcium channel 0.0025 0.0298 0.0213
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0018 0.0088 0.0088
Schistosoma mansoni gliotactin 0.0046 0.0923 0.0847
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Echinococcus granulosus solute carrier family 5 0.0038 0.0688 0.0606
Schistosoma mansoni sodium/solute symporter 0.0038 0.0688 0.0609
Echinococcus granulosus para nitrobenzyl esterase 0.0046 0.0923 0.0843
Loa Loa (eye worm) acetylcholinesterase 1 0.0271 0.776 0.776
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0046 0.0923 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0204 0.0204
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.003 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0088 0.0088
Schistosoma mansoni neurotransmitter gated ion channel 0.0018 0.0088 0.0004
Loa Loa (eye worm) GABA receptor subunit 0.0018 0.0088 0.0088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0028 0.038 0.0299
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.002 0.0133 0.0133
Schistosoma mansoni neuroligin 3 (S09 family) 0.0046 0.0923 0.0847
Echinococcus granulosus BC026374 protein S09 family 0.0046 0.0923 0.0843
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.003 0.0443 0.0359
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0038 0.0688 0.0606
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.003 0.0443 0.0359
Loa Loa (eye worm) ACC-1 protein 0.003 0.0443 0.0443
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0023 0.0217 0.5
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0023 0.0217 0.3156
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0028 0.038 0.0299
Loa Loa (eye worm) hypothetical protein 0.0018 0.0088 0.0088
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.003 0.0443 0.0359
Loa Loa (eye worm) carboxylesterase 0.0046 0.0923 0.0923
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0217 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0217 1
Onchocerca volvulus 0.003 0.0443 0.4282
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.003 0.0443 0.0363
Onchocerca volvulus 0.003 0.0443 0.4282
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0025 0.0298 0.0213
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Echinococcus granulosus glycine receptor subunit alpha 1 0.003 0.0443 0.0359
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.003 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0018 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0251 0.7146 0.7146
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.003 0.0443 0.0443
Brugia malayi Cation transporter family protein 0.003 0.0443 0.0443
Echinococcus multilocularis solute carrier family 5 0.0038 0.0688 0.0606
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0018 0.0088 0.0004
Brugia malayi Matrixin family protein 0.0018 0.0084 0.0084
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0923 0.0847
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.003 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0038 0.0688 0.0606
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0046 0.0923 0.0843
Onchocerca volvulus 0.0046 0.0923 1
Schistosoma mansoni acetylcholinesterase 0.0046 0.0923 0.0847
Echinococcus multilocularis glycine receptor subunit alpha 1 0.003 0.0443 0.0359
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0923 0.0847
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Schistosoma mansoni high-affinity choline transporter 0.0345 1 1
Onchocerca volvulus 0.0038 0.0688 0.7195
Brugia malayi Cation transporter family protein 0.003 0.0443 0.0443
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0028 0.038 0.0295
Echinococcus multilocularis voltage dependent calcium channel 0.0025 0.0298 0.0213
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.002 0.0133 0.0046
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.003 0.0443 0.0363
Onchocerca volvulus 0.0046 0.0923 1
Schistosoma mansoni voltage-gated cation channel 0.0025 0.0298 0.0216
Schistosoma mansoni inositol transporter 0.0038 0.0688 0.0609
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.003 0.0443 0.0443
Onchocerca volvulus 0.003 0.0443 0.4282
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0046 0.0923 0.0843
Echinococcus granulosus carboxylesterase 5A 0.0271 0.776 0.774
Schistosoma mansoni nAChR subunit 0.003 0.0443 0.0363
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0025 0.0298 0.0213
Schistosoma mansoni nAChR subunit 0.003 0.0443 0.0363
Onchocerca volvulus Matrix metalloproteinase homolog 0.004 0.0754 0.7985
Trichomonas vaginalis spcc417.12 protein, putative 0.0046 0.0923 1
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0923 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0923 0.0923
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.003 0.0443 0.0443
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.003 0.0443 0.0443
Onchocerca volvulus 0.0046 0.0923 1
Echinococcus multilocularis glycine receptor subunit beta 0.003 0.0443 0.0359
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0017 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0018 0.0088 0.0088
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0025 0.0298 0.0213
Echinococcus granulosus glycine receptor subunit beta 0.003 0.0443 0.0359
Onchocerca volvulus 0.003 0.0443 0.4282
Loa Loa (eye worm) calcium channel 0.0025 0.0298 0.0298
Loa Loa (eye worm) ACC-1 protein 0.003 0.0443 0.0443
Echinococcus granulosus high affinity choline transporter 1 0.0345 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.003 0.0443 0.0359
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.003 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0046 0.0923 0.0923
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.003 0.0443 0.0359
Loa Loa (eye worm) hypothetical protein 0.0271 0.776 0.776
Echinococcus multilocularis carboxylesterase 5A 0.0271 0.776 0.774
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0 0.5
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Loa Loa (eye worm) matrixin family protein 0.0044 0.0864 0.0864
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Echinococcus multilocularis acetylcholinesterase 0.0271 0.776 0.774
Loa Loa (eye worm) hypothetical protein 0.0025 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0046 0.0923 0.0923
Schistosoma mansoni nAChR subunit 0.003 0.0443 0.0363
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0023 0.0217 1
Echinococcus multilocularis inositol monophosphatase 1 0.0023 0.0217 0.0131
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0025 0.0298 0.0216
Brugia malayi Cation transporter family protein 0.003 0.0443 0.0443
Mycobacterium leprae PROBABLE HYDROLASE 0.0022 0.0204 1
Schistosoma mansoni inositol monophosphatase 0.0023 0.0217 0.0134
Trichomonas vaginalis inositol monophosphatase, putative 0.0023 0.0217 0.1772
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.003 0.0443 0.0363
Echinococcus multilocularis glycine receptor subunit alpha 1 0.003 0.0443 0.0359
Loa Loa (eye worm) hypothetical protein 0.0345 1 1
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.003 0.0443 0.0359
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0046 0.0923 0.0923
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.003 0.0443 0.0443
Onchocerca volvulus Putative nachr subunit 0.003 0.0443 0.4282
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Echinococcus multilocularis neuroligin 0.0046 0.0923 0.0843
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.003 0.0443 0.0359
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.003 0.0443 0.0363
Loa Loa (eye worm) hypothetical protein 0.0018 0.0084 0.0084
Brugia malayi Carboxylesterase family protein 0.0271 0.776 0.776
Brugia malayi Matrixin family protein 0.0018 0.0084 0.0084
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0217 1
Brugia malayi Inositol-1 0.0023 0.0217 0.0217
Onchocerca volvulus 0.0026 0.0314 0.274
Schistosoma mansoni inositol transporter 0.0038 0.0688 0.0609
Schistosoma mansoni inositol monophosphatase 0.0023 0.0217 0.0134
Loa Loa (eye worm) carboxylesterase 0.0271 0.776 0.776
Onchocerca volvulus 0.003 0.0443 0.4282
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Brugia malayi Hemopexin family protein 0.0026 0.0314 0.0314
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.003 0.0443 0.0359
Echinococcus granulosus potassium voltage gated channel subfamily H 0.002 0.0133 0.0046
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.002 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Echinococcus multilocularis para nitrobenzyl esterase 0.0046 0.0923 0.0843
Echinococcus multilocularis acetylcholinesterase 0.0271 0.776 0.774
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.003 0.0443 0.0443
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.003 0.0443 0.0359
Brugia malayi excitatory GABA receptor EXP-1A 0.003 0.0443 0.0443
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0025 0.0298 0.0213
Loa Loa (eye worm) hypothetical protein 0.0046 0.0923 0.0923
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.003 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.003 0.0443 0.0443
Echinococcus granulosus voltage dependent calcium channel 0.0025 0.0298 0.0213
Brugia malayi Matrixin family protein 0.0018 0.0084 0.0084
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.003 0.0443 0.0443
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0028 0.038 0.0295
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0018 0.0088 0.0088

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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