Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | Curated by TDR Targets | No references |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | Curated by TDR Targets | No references |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0312 | 1 | 0.5 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0312 | 1 | 0.5 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0312 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0312 | 1 | 0.5 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0312 | 1 | 1 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0312 | 1 | 0.5 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0312 | 1 | 0.5 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0312 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0233 | 0.699 | 0.699 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0312 | 1 | 1 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0312 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0233 | 0.699 | 0.699 |
Plasmodium falciparum | adenosylhomocysteinase | 0.0312 | 1 | 0.5 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0312 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0312 | 1 | 1 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0312 | 1 | 0.5 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0312 | 1 | 0.5 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0312 | 1 | 0.5 |
Echinococcus granulosus | adenosylhomocysteinase | 0.0312 | 1 | 1 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0312 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
Affected Entity | Phenotypic quality | Occurs in | Occurs at | Evidence | Observed in | Targets |
---|---|---|---|---|---|---|
catalytic activity (GO:0003824) | decreased (PATO:0000468) | inferred from specific protein inhibition (ECO:0000020) | Trypanosoma cruzi | 40469 | ||
Annotator: | millerja@u.washington.edu | Comment: | References: | 20183597 | ||
catalytic activity (GO:0003824) | decreased (PATO:0000468) | inferred from specific protein inhibition (ECO:0000020) | Trypanosoma cruzi | 44302 | ||
Annotator: | millerja@u.washington.edu | Comment: | References: | 20183597 |
1 literature reference was collected for this gene.