Detailed information for compound 563094

Basic information

Technical information
  • TDR Targets ID: 563094
  • Name: [dichloromethyl(phenoxy)phosphoryl]oxybenzene
  • MW: 317.104 | Formula: C13H11Cl2O3P
  • H donors: 0 H acceptors: 1 LogP: 4.54 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: ClC(P(=O)(Oc1ccccc1)Oc1ccccc1)Cl
  • InChi: 1S/C13H11Cl2O3P/c14-13(15)19(16,17-11-7-3-1-4-8-11)18-12-9-5-2-6-10-12/h1-10,13H
  • InChiKey: JYVKVDGSFLTXME-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • dichloromethyl O,O-diphenyl phosphonate
  • (dichloromethyl-(phenoxy)phosphoryl)oxybenzene
  • 40911-36-2
  • O,O-DIPHENYL DICHLOROMETHYLPHOSPHONATE
  • (Dichloromethyl)phosphonic acid, diphenyl

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.001 0.0009 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.034 0.2933
Echinococcus granulosus carboxylesterase 5A 0.0214 0.2635 0.3103
Brugia malayi RE15519p 0.001 0.0009 0.0016
Schistosoma mansoni hypothetical protein 0.0067 0.0738 0.0869
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0344 0.4119
Echinococcus multilocularis serotonin receptor 0.001 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0397 0.4986 0.5871
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.3722 0.646
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0337 0.0337
Brugia malayi hypothetical protein 0.0035 0.0337 0.058
Brugia malayi follicle stimulating hormone receptor 0.0457 0.5761 0.9926
Loa Loa (eye worm) hypothetical protein 0.0067 0.0738 0.1281
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.1135 0.1971
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.034 0.034
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.001 0.0009 0.0011
Echinococcus multilocularis serotonin receptor 0.001 0.0009 0.0009
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.034 0.407
Schistosoma mansoni biogenic amine receptor 0.001 0.0009 0.0011
Schistosoma mansoni hypothetical protein 0.001 0.0009 0.0011
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.001 0.0014 0.0025
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.001 0.0009 0.0011
Plasmodium falciparum importin beta, putative 0.0028 0.024 1
Echinococcus granulosus hypothetical protein 0.001 0.0009 0.0011
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0036 0.0346 0.0346
Schistosoma mansoni survival motor neuron protein 0.0047 0.0482 0.0567
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0145 0.0249
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.081 1
Schistosoma mansoni hypothetical protein 0.0047 0.0482 0.0567
Brugia malayi gonadotropin-releasing hormone receptor 2 0.001 0.0009 0.0016
Onchocerca volvulus 0.0036 0.0344 0.244
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0134 0.0233
Schistosoma mansoni hypothetical protein 0.0011 0.0021 0.0025
Echinococcus multilocularis polycystic kidney disease protein 2 0.0011 0.0017 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0009 0.0009
Brugia malayi beta-lactamase family protein 0.0036 0.0344 0.0592
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.001 0.0009 0.0016
Mycobacterium tuberculosis Carboxylesterase LipT 0.0036 0.0346 0.0007
Onchocerca volvulus 0.001 0.0009 0.0065
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.034 0.04
Schistosoma mansoni microtubule-associated protein tau 0.0669 0.8492 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.001 0.0009 0.0065
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0134 0.0158
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0145 0.0251
Onchocerca volvulus 0.0028 0.0238 0.1692
Brugia malayi Carboxylesterase family protein 0.0036 0.0346 0.0595
Echinococcus multilocularis acetylcholinesterase 0.0214 0.2635 0.2635
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0086
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0172 0.1948
Brugia malayi putative neuropeptide receptor 0.001 0.0009 0.0016
Brugia malayi hypothetical protein 0.001 0.0009 0.0016
Echinococcus granulosus somatostatin receptor 0.001 0.0009 0.0011
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.001 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0346 0.06
Loa Loa (eye worm) hypothetical protein 0.0036 0.0346 0.06
Echinococcus multilocularis neuropeptides capa receptor 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0214 0.2635 0.4575
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0036 0.0346 0.0407
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0.0009 0.0009
Onchocerca volvulus 0.0036 0.0344 0.244
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0025
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0042 0.0042
Trichomonas vaginalis inositol monophosphatase, putative 0.0072 0.081 1
Schistosoma mansoni wnt-5 0.0013 0.0049 0.0058
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.034 0.04
Schistosoma mansoni neuropeptide receptor 0.001 0.0009 0.0011
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0036 0.0346 0.0407
Echinococcus multilocularis neuropeptides capa receptor 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Brugia malayi Carboxylesterase family protein 0.0214 0.2635 0.4541
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0134 0.0232
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0009 0.0011
Schistosoma mansoni neuropeptide receptor 0.001 0.0009 0.0011
Echinococcus granulosus lamin 0.0026 0.0217 0.0255
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0134 0.0232
Loa Loa (eye worm) hypothetical protein 0.0036 0.0344 0.0597
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.002 0.0134 0.0233
Leishmania major hypothetical protein, conserved 0.0036 0.0344 0.4119
Schistosoma mansoni lamin 0.0026 0.0217 0.0255
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0134 0.0232
Echinococcus multilocularis microtubule associated protein 2 0.0669 0.8492 0.8492
Loa Loa (eye worm) hypothetical protein 0.0031 0.0277 0.0481
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0344 0.0597
Loa Loa (eye worm) hypothetical protein 0.0026 0.0217 0.0376
Schistosoma mansoni nuclear hormone receptor 0.002 0.0134 0.0158
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Echinococcus granulosus polycystin 2 0.0011 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Brugia malayi intermediate filament protein 0.0026 0.0217 0.0373
Schistosoma mansoni coup transcription factor 0.002 0.0134 0.0158
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0145 0.1608
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.001 0.0009 0.0011
Schistosoma mansoni histamine h1 receptor 0.001 0.0009 0.0011
Echinococcus multilocularis neuropeptide s receptor 0.0456 0.5751 0.5751
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.001 0.0009 0.0009
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.0009 0.0011
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0277 0.0326
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0036 0.0346 0.0007
Loa Loa (eye worm) hypothetical protein 0.0119 0.1409 0.2446
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0134 0.0232
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.034 0.407
Onchocerca volvulus 0.001 0.0009 0.0065
Echinococcus multilocularis protein Wnt 2 0.0013 0.0049 0.0049
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.001 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0298 0.3722 0.4382
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0344 0.0592
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.034 0.2933
Schistosoma mansoni biogenic amine (5HT) receptor 0.001 0.0009 0.0011
Schistosoma mansoni opsin-like receptor 0.001 0.0009 0.0011
Echinococcus granulosus GPCR family 2 0.0031 0.0277 0.0326
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0134 0.0232
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0009 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0451 0.0531
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0014 0.0017
Schistosoma mansoni thyroid hormone receptor 0.002 0.0134 0.0158
Loa Loa (eye worm) hypothetical protein 0.0214 0.2635 0.4575
Echinococcus granulosus tachykinin peptides receptor 99D 0.001 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0238 0.0414
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.034 0.04
Loa Loa (eye worm) hypothetical protein 0.0119 0.1409 0.2446
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0172 0.0405
Echinococcus multilocularis biogenic amine (5HT) receptor 0.001 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0031 0.0277 0.0326
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.001 0.0009 0.0011
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0482 0.083
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0134 0.0232
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.034 0.2933
Echinococcus granulosus serotonin receptor 0.001 0.0009 0.0011
Echinococcus multilocularis WNT 0.0013 0.0049 0.0049
Echinococcus granulosus g protein coupled receptor 0.001 0.0009 0.0011
Schistosoma mansoni hypothetical protein 0.0031 0.0277 0.0326
Loa Loa (eye worm) hypothetical protein 0.0036 0.034 0.059
Echinococcus granulosus neuropeptide FF receptor 2 0.001 0.0009 0.0011
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0738 0.1272
Brugia malayi nuclear receptor RXR 0.001 0.0014 0.0025
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0451 0.0451
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0172 0.0405
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0145 0.1608
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0036 0.0346 0.0407
Brugia malayi Inositol-1 0.0072 0.081 0.1396
Echinococcus granulosus Protein Wnt-111 0.0013 0.0049 0.0058
Echinococcus granulosus mucolipin 3 0.0128 0.1522 0.1793
Schistosoma mansoni growth hormone secretagogue receptor 0.001 0.0009 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0009 0.0011
Echinococcus multilocularis cpg binding protein 0.0029 0.0259 0.0259
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0134 0.0158
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0451 0.0451
Onchocerca volvulus 0.0026 0.0217 0.1537
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0025
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0134 0.0158
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0086
Loa Loa (eye worm) hypothetical protein 0.0036 0.0346 0.06
Schistosoma mansoni opsin-like receptor 0.001 0.0009 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0009 0.0011
Schistosoma mansoni hypothetical protein 0.0011 0.0017 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0134 0.0158
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0009 0.0009
Loa Loa (eye worm) melatonin receptor type 1A 0.001 0.0009 0.0016
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0172 0.0405
Echinococcus multilocularis alpha 1A adrenergic receptor 0.001 0.0009 0.0009
Echinococcus granulosus g-protein coupled receptor 0.001 0.0009 0.0011
Echinococcus multilocularis wingless type MMTV integration site family 0.0013 0.0049 0.0049
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.001 0.0009 0.0016
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0065 0.0713 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0134 0.0233
Echinococcus multilocularis inositol monophosphatase 1 0.0072 0.081 0.081
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0134 0.0158
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.001 0.0009 0.0016
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.001 0.0009 0.0011
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0344 0.364
Brugia malayi G-protein coupled receptor 0.001 0.0009 0.0016
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0134 0.0954
Echinococcus multilocularis G protein coupled receptor 139 0.001 0.0009 0.0009
Echinococcus multilocularis importin subunit beta 1 0.0028 0.024 0.024
Onchocerca volvulus 0.001 0.0009 0.0065
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.034 0.407
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0451 0.0777
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0277 0.0326
Loa Loa (eye worm) hypothetical protein 0.002 0.0134 0.0233
Echinococcus granulosus intermediate filament protein 0.0026 0.0217 0.0255
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0077 0.0753
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0134 0.0233
Schistosoma mansoni biogenic amine receptor 0.001 0.0009 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0451 0.0531
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0195 0.2237
Schistosoma mansoni polycystin 1-related 0.0011 0.0017 0.002
Echinococcus granulosus neuropeptide receptor 0.001 0.0009 0.0011
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0195 0.2237
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.001 0.0009 0.0011
Entamoeba histolytica hypothetical protein 0.0023 0.0172 0.0405
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0077 0.0134
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.001 0.0009 0.0011
Onchocerca volvulus 0.001 0.0009 0.0065
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.4986 0.4986
Mycobacterium tuberculosis Possible penicillin-binding protein 0.023 0.2843 1
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0009 0.0011
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0277 0.0478
Brugia malayi hypothetical protein 0.0016 0.0083 0.0143
Schistosoma mansoni opsin-like receptor 0.001 0.0009 0.0011
Schistosoma mansoni neuropeptide F-like receptor 0.001 0.0009 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0344 0.2991
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0009 0.0011
Echinococcus granulosus Polycystic kidney disease protein 0.0011 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Schistosoma mansoni mucolipin 0.0128 0.1522 0.1793
Schistosoma mansoni amine GPCR 0.001 0.0009 0.0011
Echinococcus granulosus BC026374 protein S09 family 0.0036 0.0346 0.0407
Echinococcus granulosus snurportin 1 0.0298 0.3722 0.4382
Echinococcus granulosus 7TM GPCR rhodopsin 0.001 0.0009 0.0011
Brugia malayi hypothetical protein 0.001 0.0009 0.0016
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.001 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Mycobacterium ulcerans hypothetical protein 0.0036 0.0344 0.364
Schistosoma mansoni lamin 0.0026 0.0217 0.0255
Schistosoma mansoni adenoreceptor 0.001 0.0009 0.0011
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.034 0.407
Schistosoma mansoni inositol monophosphatase 0.0072 0.081 0.0954
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0134 0.0232
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0451 0.0531
Brugia malayi hypothetical protein 0.001 0.0009 0.0016
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.081 1
Echinococcus multilocularis orexin receptor type 2 0.001 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0134 0.0232
Leishmania major cytochrome p450-like protein 0.0015 0.0077 0.0753
Schistosoma mansoni myosin xvIII 0.001 0.0009 0.0011
Echinococcus multilocularis sex peptide receptor 0.001 0.0009 0.0009
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0337 0.0397
Trichomonas vaginalis spcc417.12 protein, putative 0.0036 0.0346 0.3017
Schistosoma mansoni gliotactin 0.0036 0.0346 0.0407
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0217 0.0376
Brugia malayi wnt family protein 0.0013 0.0049 0.0085
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0009 0.0009
Echinococcus granulosus neuropeptides capa receptor 0.001 0.0009 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0277 0.0478
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0.0009 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0009 0.0011
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0072 0.081 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Brugia malayi CXXC zinc finger family protein 0.0028 0.0238 0.0411
Loa Loa (eye worm) hypothetical protein 0.0036 0.0344 0.0597
Echinococcus granulosus geminin 0.0164 0.1995 0.2349
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0134 0.0158
Brugia malayi neuropeptide F receptor 0.001 0.0009 0.0016
Onchocerca volvulus 0.001 0.0009 0.0065
Schistosoma mansoni amine GPCR 0.001 0.0009 0.0011
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0.0009 0.0011
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0344 0.0405
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0134 0.0134
Echinococcus granulosus protein Wnt 1 0.0013 0.0049 0.0058
Brugia malayi nuclear receptor NHR-88 0.002 0.0134 0.0232
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.001 0.0009 0.0016
Brugia malayi wnt family protein 0.0013 0.0049 0.0085
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0077 0.0753
Schistosoma mansoni hypothetical protein 0.0164 0.1995 0.2349
Onchocerca volvulus 0.001 0.0009 0.0065
Brugia malayi Wnt-4 protein precursor 0.0013 0.0049 0.0085
Echinococcus multilocularis g protein coupled receptor 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Brugia malayi hypothetical protein 0.001 0.0009 0.0016
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0021 0.0021
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.001 0.0009 0.0009
Brugia malayi Serotonin receptor 0.001 0.0009 0.0016
Echinococcus granulosus microtubule associated protein 2 0.0669 0.8492 1
Onchocerca volvulus 0.001 0.0009 0.0065
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0451 0.0531
Schistosoma mansoni hypothetical protein 0.0031 0.0277 0.0326
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0072 0.081 1
Echinococcus multilocularis protein Wnt 1 0.0013 0.0049 0.0049
Brugia malayi hypothetical protein 0.0119 0.1409 0.2427
Echinococcus granulosus g protein coupled receptor 0.001 0.0009 0.0011
Loa Loa (eye worm) G-protein coupled receptor 0.001 0.0009 0.0016
Echinococcus multilocularis snurportin 1 0.0298 0.3722 0.3722
Echinococcus multilocularis WNT 0.0013 0.0049 0.0049
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0559 0.6835
Brugia malayi Cytochrome P450 family protein 0.0015 0.0077 0.0133
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Echinococcus granulosus neuropeptide receptor 0.001 0.0009 0.0011
Brugia malayi Cytochrome P450 family protein 0.0015 0.0077 0.0133
Brugia malayi AKH receptor 0.001 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0036 0.0063
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0009 0.0011
Schistosoma mansoni cpg binding protein 0.0028 0.0238 0.0281
Echinococcus granulosus polycystic kidney disease protein 2 0.0011 0.0017 0.002
Loa Loa (eye worm) TYRA-2 protein 0.001 0.0009 0.0016
Schistosoma mansoni hypothetical protein 0.0011 0.0017 0.002
Brugia malayi Serotonin/octopamine receptor family protein 7 0.001 0.0009 0.0016
Echinococcus granulosus alpha 1A adrenergic receptor 0.001 0.0009 0.0011
Brugia malayi nuclear hormone receptor 0.002 0.0134 0.0232
Echinococcus multilocularis neuroligin 0.0036 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0025
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.2831 0.3334
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0009 0.0009
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0277 0.0481
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0072 0.081 0.5
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0134 0.0233
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Echinococcus multilocularis wnt family member wnt11 2 0.0013 0.0049 0.0049
Loa Loa (eye worm) inositol-1 0.0072 0.081 0.1406
Echinococcus granulosus Protein Wnt-5 0.0013 0.0049 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0025
Echinococcus granulosus neuropeptide s receptor 0.0456 0.5751 0.6772
Schistosoma mansoni hypothetical protein 0.001 0.0009 0.0011
Schistosoma mansoni hypothetical protein 0.0031 0.0277 0.0326
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.001 0.0009 0.0011
Schistosoma mansoni amine GPCR 0.001 0.0009 0.0011
Loa Loa (eye worm) G-protein coupled receptor 0.001 0.0009 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0134 0.0232
Onchocerca volvulus 0.002 0.0134 0.0954
Schistosoma mansoni hypothetical protein 0.0035 0.0337 0.0397
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Mycobacterium ulcerans carboxylesterase, LipT 0.0036 0.0346 0.3663
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.034 0.04
Echinococcus granulosus peptide allatostatin:somatostatin 0.001 0.0009 0.0011
Schistosoma mansoni cpg binding protein 0.0029 0.0259 0.0305
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.001 0.0009 0.0016
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.024 0.2807
Echinococcus multilocularis BC026374 protein (S09 family) 0.0036 0.0346 0.0346
Echinococcus multilocularis g protein coupled receptor 0.001 0.0009 0.0009
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0451 0.0783
Toxoplasma gondii ABC1 family protein 0.0036 0.0344 0.4119
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0009 0.0009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.001 0.0009 0.0011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.064 0.0754
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0134 0.0233
Brugia malayi Dopamine receptor protein 1 0.001 0.0009 0.0016
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.1135 0.1956
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0009 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0344 0.4119
Schistosoma mansoni neuropeptide F-like receptor 0.001 0.0009 0.0011
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.024 0.2807
Echinococcus multilocularis Polycystic kidney disease protein 0.0011 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0035 0.0337 0.2888
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Echinococcus granulosus acetylcholinesterase 0.0214 0.2635 0.3103
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0134 0.0158
Loa Loa (eye worm) hypothetical protein 0.0012 0.0036 0.0063
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0134 0.0134
Onchocerca volvulus 0.0036 0.0346 0.2452
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.024 0.2807
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0277 0.0277
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.034 0.034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0451 0.0531
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0134 0.0134
Schistosoma mansoni biogenic amine receptor 0.001 0.0009 0.0011
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.001 0.0009 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0134 0.0232
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0009 0.0011
Leishmania major importin beta-1 subunit, putative 0.0023 0.0172 0.1948
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0036 0.0346 0.0007
Schistosoma mansoni neuroligin 3 (S09 family) 0.0036 0.0346 0.0407
Brugia malayi Carboxylesterase family protein 0.0214 0.2635 0.4541
Schistosoma mansoni hypothetical protein 0.0164 0.1995 0.2349
Schistosoma mansoni intermediate filament proteins 0.0026 0.0217 0.0255
Echinococcus multilocularis para nitrobenzyl esterase 0.0036 0.0346 0.0346
Onchocerca volvulus 0.0047 0.0482 0.342
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0134 0.0158
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0134 0.0158
Loa Loa (eye worm) hypothetical protein 0.002 0.0134 0.0233
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0134 0.0233
Loa Loa (eye worm) acetylcholinesterase 1 0.0214 0.2635 0.4575
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0134 0.0232
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0036 0.0346 0.0407
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0036 0.0344 0.0597
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.034 0.2933
Loa Loa (eye worm) hypothetical protein 0.0036 0.0344 0.0597
Schistosoma mansoni hypothetical protein 0.001 0.0009 0.0011
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.001 0.0014 0.0017
Echinococcus granulosus Protein Wnt-04 0.0013 0.0049 0.0058
Echinococcus granulosus neuroligin 0.0036 0.0346 0.0407
Schistosoma mansoni inositol monophosphatase 0.0072 0.081 0.0954
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0344 0.2991
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0134 0.0158
Brugia malayi hypothetical protein 0.001 0.0014 0.0025
Echinococcus multilocularis neuropeptide Y receptor 0.001 0.0009 0.0009
Echinococcus granulosus para nitrobenzyl esterase 0.0036 0.0346 0.0407
Echinococcus multilocularis fmrfamide receptor 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0024 0.0195 0.0338
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0134 0.0233
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0014 0.0025
Brugia malayi hypothetical protein 0.0036 0.0346 0.0595
Brugia malayi hypothetical protein 0.001 0.0009 0.0016
Onchocerca volvulus 0.001 0.0009 0.0065
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.081 1
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0134 0.0158
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0.0009 0.0011
Onchocerca volvulus 0.001 0.0009 0.0065
Echinococcus granulosus allatostatin A receptor 0.001 0.0009 0.0011
Loa Loa (eye worm) neuropeptide F receptor 0.001 0.0009 0.0016
Onchocerca volvulus 0.0036 0.0346 0.2452
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0086
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.0009 0.0011
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.001 0.0009 0.0011
Entamoeba histolytica hypothetical protein 0.0035 0.0337 0.2888
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.2831 0.2831
Schistosoma mansoni amine GPCR 0.001 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Schistosoma mansoni cpg binding protein 0.0029 0.0259 0.0305
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0134 0.0232
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0344 0.0405
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0344 0.2991
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0009 0.0009
Onchocerca volvulus 0.001 0.0009 0.0065
Echinococcus multilocularis allatostatin A receptor 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0195 0.2237
Schistosoma mansoni wnt related 0.0013 0.0049 0.0058
Brugia malayi hypothetical protein 0.0229 0.2831 0.4878
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Onchocerca volvulus 0.001 0.0009 0.0065
Brugia malayi hypothetical protein 0.001 0.0009 0.0016
Echinococcus granulosus dro:myosuppressin receptor 0.001 0.0009 0.0011
Onchocerca volvulus 0.001 0.0009 0.0065
Brugia malayi RNA, U transporter 1 0.0079 0.0903 0.1556
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.001 0.0009 0.0065
Loa Loa (eye worm) hypothetical protein 0.0229 0.2831 0.4914
Brugia malayi larval opioid receptor 0.001 0.0009 0.0016
Echinococcus granulosus protein Wnt 2 0.0013 0.0049 0.0058
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0134 0.0134
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0344 0.2991
Echinococcus multilocularis musashi 0.0026 0.0217 0.0217
Loa Loa (eye worm) Wnt2 protein 0.0013 0.0049 0.0086
Echinococcus granulosus neuropeptide Y receptor 0.001 0.0009 0.0011
Onchocerca volvulus 0.0036 0.0346 0.2452
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.001 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.001 0.0014 0.0017
Echinococcus granulosus orexin receptor type 2 0.001 0.0009 0.0011
Loa Loa (eye worm) carboxylesterase 0.0036 0.0346 0.06
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0086
Brugia malayi G protein-coupled receptor 0.001 0.0009 0.0016
Brugia malayi Dopamine receptor protein 2 0.001 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0036 0.0344 0.0597
Brugia malayi Melatonin receptor type 1A 0.001 0.0009 0.0016
Brugia malayi Tachykinin-like peptides receptor 99D 0.001 0.0009 0.0016
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0077 0.0134
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0145 0.0145
Echinococcus granulosus sex peptide receptor 0.001 0.0009 0.0011
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.1135 0.1956
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.006 0.0105
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0009 0.0011
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0134 0.0134
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0009 0.0011
Brugia malayi hypothetical protein 0.0024 0.0195 0.0335
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0021 0.0025
Brugia malayi hypothetical protein 0.001 0.0009 0.0016
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.081 1
Brugia malayi hypothetical protein 0.001 0.0014 0.0025
Echinococcus granulosus neuropeptide receptor A26 0.0456 0.5751 0.6772
Brugia malayi GnHR receptor homolog 0.001 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Schistosoma mansoni biogenic amine (5HT) receptor 0.001 0.0009 0.0011
Brugia malayi Serotonin receptor 0.046 0.5804 1
Brugia malayi wnt family protein 0.0013 0.0049 0.0085
Brugia malayi sulfakinin receptor protein 0.001 0.0009 0.0016
Loa Loa (eye worm) carboxylesterase 0.0214 0.2635 0.4575
Loa Loa (eye worm) hypothetical protein 0.0013 0.0042 0.0074
Loa Loa (eye worm) hypothetical protein 0.002 0.0134 0.0233
Schistosoma mansoni mucolipin 0.0117 0.1385 0.1631
Schistosoma mansoni alpha-1 adrenergic receptor 0.001 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Schistosoma mansoni neuropeptide receptor 0.001 0.0009 0.0011
Brugia malayi Dopamine receptor 0.001 0.0009 0.0016
Brugia malayi Carboxylesterase family protein 0.0036 0.0346 0.0595
Loa Loa (eye worm) hypothetical protein 0.0036 0.0346 0.06
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0009 0.0011
Onchocerca volvulus 0.001 0.0009 0.0065
Brugia malayi beta-lactamase family protein 0.0036 0.0344 0.0592
Brugia malayi hypothetical protein 0.001 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0042 0.005
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Leishmania major hypothetical protein, conserved 0.0024 0.0195 0.2237
Loa Loa (eye worm) hypothetical protein 0.0036 0.0344 0.0597
Echinococcus multilocularis somatostatin receptor 0.001 0.0009 0.0009
Echinococcus multilocularis dro:myosuppressin receptor 0.001 0.0009 0.0009
Loa Loa (eye worm) mucolipin 1 0.0128 0.1522 0.2642
Brugia malayi beta-lactamase 0.0036 0.0344 0.0592
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0195 0.2237
Brugia malayi Wnt-2 protein precursor 0.0013 0.0049 0.0085
Echinococcus granulosus acetylcholinesterase 0.0214 0.2635 0.3103
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.001 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Mycobacterium ulcerans beta-lactamase 0.0036 0.0344 0.364
Brugia malayi G-protein coupled receptor 0.001 0.0009 0.0016
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0134 0.0134
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0195 0.2503
Echinococcus multilocularis G-protein coupled receptor, putative 0.001 0.0009 0.0009
Brugia malayi G protein-coupled receptor F59B2.13 0.001 0.0009 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0009 0.0009
Echinococcus multilocularis carboxylesterase 5A 0.0214 0.2635 0.2635
Entamoeba histolytica hypothetical protein 0.0035 0.0337 0.2888
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.034 0.04
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0077 0.0134
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0344 0.4119
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0077 0.0753
Loa Loa (eye worm) hypothetical protein 0.0098 0.1135 0.1971
Echinococcus granulosus importin subunit beta 1 0.0028 0.024 0.0282
Echinococcus granulosus neuropeptide Y receptor 0.001 0.0009 0.0011
Brugia malayi hypothetical protein 0.001 0.0009 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0134 0.0232
Echinococcus multilocularis g protein coupled receptor 0.001 0.0009 0.0009
Brugia malayi Carboxylesterase family protein 0.0036 0.0346 0.0595
Leishmania major GTP-binding protein, putative 0.0021 0.0145 0.1608
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0337 0.0397
Echinococcus multilocularis fmrfamide receptor 0.001 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0035 0.0337 0.2888
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0214 0.2635 0.3103
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0277 0.0277
Brugia malayi Coelomocyte uptake defective protein 5 0.0128 0.1522 0.2623
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0344 0.2991
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0457 0.5761 1
Echinococcus multilocularis neuropeptide Y receptor 0.001 0.0009 0.0009
Echinococcus granulosus neuropeptides capa receptor 0.001 0.0009 0.0011
Brugia malayi ecdysteroid receptor 0.002 0.0134 0.0232
Loa Loa (eye worm) hypothetical protein 0.0028 0.024 0.0416
Brugia malayi wnt family protein 0.0013 0.0049 0.0085
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.081 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0145 0.0171
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Onchocerca volvulus 0.001 0.0009 0.0065
Loa Loa (eye worm) hypothetical protein 0.0036 0.0346 0.06
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Echinococcus multilocularis neuropeptide FF receptor 2 0.001 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0134 0.0232
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.002 0.0134 0.0233
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Schistosoma mansoni wnt related 0.0013 0.0049 0.0058
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.081 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0134 0.0158
Loa Loa (eye worm) neuropeptide F receptor 0.001 0.0009 0.0016
Echinococcus granulosus FTZ F1 alpha 0.002 0.0134 0.0158
Onchocerca volvulus 0.0026 0.0217 0.1537
Mycobacterium ulcerans lipase LipD 0.0036 0.0344 0.364
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0009 0.0011
Brugia malayi steroid hormone receptor 0.002 0.0134 0.0232
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0134 0.0158
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.002 0.0134 0.0233
Schistosoma mansoni wnt related 0.0013 0.0049 0.0058
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0217 0.0373
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.006 0.0104
Echinococcus granulosus fmrfamide receptor 0.001 0.0009 0.0011
Brugia malayi Carboxylesterase family protein 0.0036 0.0346 0.0595
Brugia malayi putative neuropeptide receptor NPR1 0.001 0.0009 0.0016
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.034 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.0009 0.0011
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0134 0.0158
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Trichomonas vaginalis esterase, putative 0.0036 0.0344 0.2991
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0145 0.1608
Echinococcus multilocularis g-protein coupled receptor 0.001 0.0009 0.0009
Echinococcus granulosus lamin dm0 0.0026 0.0217 0.0255
Onchocerca volvulus Huntingtin homolog 0.0119 0.1409 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.001 0.0009 0.0011
Schistosoma mansoni neuropeptide receptor 0.001 0.0009 0.0011
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.034 0.034
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0344 1
Echinococcus multilocularis lamin dm0 0.0026 0.0217 0.0217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0009 0.0011
Loa Loa (eye worm) wnt-4 protein 0.0013 0.0049 0.0086
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0072 0.081 1
Brugia malayi Importin beta-1 subunit 0.0028 0.024 0.0413
Echinococcus granulosus G protein coupled receptor 139 0.001 0.0009 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0009 0.0009
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0014 0.0025
Onchocerca volvulus 0.0036 0.0346 0.2452
Echinococcus multilocularis GPCR, family 2 0.0031 0.0277 0.0277
Loa Loa (eye worm) beta-lactamase 0.0036 0.0344 0.0597
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.021 0.0365
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0134 0.0232
Echinococcus granulosus Protein Wnt-11b 0.0013 0.0049 0.0058
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0134 0.0158
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0217 0.0376
Brugia malayi ORL1-like opioid receptor 0.001 0.0009 0.0016
Echinococcus multilocularis acetylcholinesterase 0.0214 0.2635 0.2635
Loa Loa (eye worm) hypothetical protein 0.002 0.0134 0.0233
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0195 0.5242
Loa Loa (eye worm) carboxylesterase 0.0036 0.0346 0.06
Schistosoma mansoni ran 0.0021 0.0145 0.0171
Echinococcus granulosus cpg binding protein 0.0029 0.0259 0.0305
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0134 0.0954
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0009 0.0011
Onchocerca volvulus 0.001 0.0009 0.0065
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.001 0.0009 0.0009
Schistosoma mansoni BC026374 protein (S09 family) 0.0036 0.0346 0.0407
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.001 0.0009 0.0011
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0036 0.0346 0.3017
Echinococcus granulosus dnaJ subfamily B 0.0397 0.4986 0.5871
Echinococcus granulosus g protein coupled receptor 0.001 0.0009 0.0011
Echinococcus multilocularis geminin 0.0164 0.1995 0.1995
Schistosoma mansoni neuropeptide f receptor 76f 0.001 0.0009 0.0011
Schistosoma mansoni thyroid hormone receptor 0.002 0.0134 0.0158
Echinococcus granulosus 7tm_1 domain containing protein 0.001 0.0009 0.0011
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0134 0.0954
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0065 0.0713 0.1475
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0344 0.0405
Loa Loa (eye worm) CWN-2 protein 0.0013 0.0049 0.0086
Echinococcus multilocularis mucolipin 3 0.0128 0.1522 0.1522
Plasmodium vivax importin-beta 2, putative 0.0028 0.024 0.4774
Echinococcus multilocularis lamin 0.0026 0.0217 0.0217
Schistosoma mansoni importin beta-1 0.0028 0.024 0.0282
Schistosoma mansoni ran 0.0021 0.0145 0.0171
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0145 0.1608
Onchocerca volvulus Huntingtin homolog 0.0119 0.1409 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Brugia malayi neuropeptide F receptor 0.001 0.0009 0.0016
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0134 0.0158
Echinococcus multilocularis neuropeptide receptor A26 0.0456 0.5751 0.5751
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0.0009 0.0011
Schistosoma mansoni acetylcholinesterase 0.0036 0.0346 0.0407
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0134 0.0158
Loa Loa (eye worm) hypothetical protein 0.0036 0.0346 0.06
Loa Loa (eye worm) hypothetical protein 0.0036 0.0346 0.06
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.001 0.0009 0.0009
Echinococcus multilocularis neuropeptide receptor 0.001 0.0009 0.0009
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0134 0.0232
Brugia malayi hypothetical protein 0.001 0.0009 0.0016
Onchocerca volvulus 0.0036 0.0346 0.2452
Loa Loa (eye worm) hypothetical protein 0.002 0.0134 0.0233
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.034 0.0586
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0086
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0016
Onchocerca volvulus 0.0036 0.0344 0.244
Schistosoma mansoni peptide (allatostatin)-like receptor 0.001 0.0009 0.0011
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0344 0.364
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0134 0.0233
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0009 0.0011
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0195 0.5242
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0009 0.0011
Schistosoma mansoni wnt related 0.0013 0.0049 0.0058
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0009 0.0009
Echinococcus multilocularis neuropeptide receptor 0.001 0.0009 0.0009
Echinococcus multilocularis tachykinin peptides receptor 99D 0.001 0.0009 0.0009
Onchocerca volvulus 0.001 0.0009 0.0065
Schistosoma mansoni amine GPCR 0.001 0.0009 0.0011
Echinococcus granulosus inositol monophosphatase 1 0.0072 0.081 0.0954

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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