Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | RNA binding protein | 0.013 | 0.4054 | 0.4054 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0268 | 1 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0268 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0185 | 0.6446 | 0.1027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0268 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0268 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0268 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0185 | 0.6446 | 0.1027 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.4054 | 0.6952 |
Echinococcus granulosus | geminin | 0.0171 | 0.5832 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.5832 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.052 | 0.0892 |
Brugia malayi | RNA binding protein | 0.013 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.052 | 0.052 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.5832 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0268 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0704 | 0.0704 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0176 | 0.6039 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.4054 | 0.6952 |
Loa Loa (eye worm) | TAR-binding protein | 0.013 | 0.4054 | 0.4054 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.052 | 0.0892 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.013 | 0.4054 | 0.4054 |
Brugia malayi | RNA recognition motif domain containing protein | 0.013 | 0.4054 | 0.4054 |
Brugia malayi | TAR-binding protein | 0.013 | 0.4054 | 0.4054 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0704 | 0.0704 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.4054 | 0.6952 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.052 | 0.052 |
Echinococcus multilocularis | tar DNA binding protein | 0.013 | 0.4054 | 0.6653 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0268 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.4054 | 0.6952 |
Echinococcus granulosus | tar DNA binding protein | 0.013 | 0.4054 | 0.6653 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.052 | 0.0892 |
Echinococcus multilocularis | geminin | 0.0171 | 0.5832 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0704 | 0.0704 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0704 | 0.0704 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.4054 | 0.6952 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.