Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | disco interacting protein 2 | 0.0038 | 0.3692 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.3006 | 0.8141 |
Trypanosoma brucei | cytosine-specific DNA methylase, putative | 0.0019 | 0.1124 | 0.5 |
Echinococcus multilocularis | DNA methyltransferase 2, putative | 0.0019 | 0.1124 | 0.3043 |
Toxoplasma gondii | hypothetical protein | 0.0083 | 1 | 1 |
Leishmania major | modification methylase-like protein | 0.0019 | 0.1124 | 0.5 |
Schistosoma mansoni | DNA (cytosine-5)-methyltransferase | 0.0019 | 0.1124 | 0.3043 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.3006 | 0.8141 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.041 | 0.0892 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.3006 | 0.8141 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.3006 | 0.8096 |
Brugia malayi | Disco-interacting protein 2 homolog | 0.0038 | 0.3692 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.3692 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.3006 | 0.8141 |
Onchocerca volvulus | 0.0038 | 0.3692 | 1 | |
Echinococcus multilocularis | roundabout 2 | 0.0014 | 0.041 | 0.1111 |
Schistosoma mansoni | cell adhesion molecule | 0.0012 | 0.0089 | 0.0241 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.3006 | 0.8096 |
Entamoeba histolytica | DNA (cytosine-5)-methyltransferase, putative | 0.0019 | 0.1124 | 0.5 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0012 | 0.0089 | 0.0241 |
Echinococcus granulosus | DNA methyltransferase 2, putative | 0.0019 | 0.1124 | 0.3043 |
Echinococcus multilocularis | disco interacting protein 2 | 0.0038 | 0.3692 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.041 | 0.0892 |
Echinococcus granulosus | roundabout 2 | 0.0014 | 0.041 | 0.1111 |
Schistosoma mansoni | disco-interacting protein 2 (dip2) | 0.0038 | 0.3692 | 1 |
Plasmodium vivax | DNA (cytosine-5)-methyltransferase, putative | 0.0019 | 0.1124 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.3006 | 0.8141 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.