Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0363 | 0.1512 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Echinococcus granulosus | serine protein kinase ATM | 0.0026 | 0.0242 | 0.0685 |
Giardia lamblia | Beta tubulin | 0.0019 | 0.013 | 0.181 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0019 | 0.0121 | 0.0121 |
Toxoplasma gondii | beta-tubulin, putative | 0.0019 | 0.013 | 0.013 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0245 | 0.2077 |
Echinococcus granulosus | tubulin beta 1 chain | 0.0019 | 0.013 | 0.0284 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0245 | 0.249 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0245 | 0.0116 |
Echinococcus multilocularis | beta tubulin | 0.0019 | 0.013 | 0.0284 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0019 | 0.0121 | 0.0503 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0036 | 0.0417 | 0.0417 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0036 | 0.0417 | 0.0417 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0245 | 0.1019 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0049 | 0.0204 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0019 | 0.0121 | 0.025 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0019 | 0.013 | 0.0284 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.1021 | 0.4129 |
Schistosoma mansoni | tubulin subunit alpha | 0.0036 | 0.0417 | 0.1313 |
Echinococcus multilocularis | tubulin beta 1 chain | 0.0019 | 0.013 | 0.0284 |
Loa Loa (eye worm) | alpha-tubulin | 0.0036 | 0.0417 | 0.1738 |
Echinococcus multilocularis | tubulin alpha chain | 0.0036 | 0.0417 | 0.1313 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.004 | 0.0487 | 0.4679 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0019 | 0.013 | 0.013 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0019 | 0.0121 | 0.0748 |
Schistosoma mansoni | dihydropteridine reductase | 0.004 | 0.0487 | 0.1561 |
Giardia lamblia | Gamma tubulin | 0.0019 | 0.013 | 0.181 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0019 | 0.013 | 0.0284 |
Loa Loa (eye worm) | BEN-1 protein | 0.0019 | 0.013 | 0.0543 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0026 | 0.0242 | 0.0685 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0019 | 0.0121 | 0.0748 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0044 | 0.0562 | 0.0562 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Trypanosoma brucei | alpha tubulin | 0.0036 | 0.0417 | 0.4249 |
Brugia malayi | Tubulin alpha-2 chain | 0.0036 | 0.0417 | 0.1559 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0585 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0585 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Leishmania major | epsilon tubulin, putative | 0.0019 | 0.013 | 0.085 |
Echinococcus multilocularis | tubulin, beta 4A class IVa | 0.0019 | 0.013 | 0.0284 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.004 | 0.0487 | 0.1561 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Trypanosoma brucei | beta tubulin | 0.0019 | 0.013 | 0.1327 |
Echinococcus multilocularis | hypothetical protein | 0.0036 | 0.0417 | 0.1313 |
Giardia lamblia | Beta tubulin | 0.0019 | 0.013 | 0.181 |
Echinococcus granulosus | tubulin alpha chain | 0.0036 | 0.0417 | 0.1313 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0027 | 0.0272 | 0.0272 |
Trypanosoma brucei | beta tubulin | 0.0019 | 0.013 | 0.1327 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0363 | 0.1118 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0019 | 0.0121 | 0.0748 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0618 | 0.2031 |
Giardia lamblia | Alpha-tubulin | 0.0036 | 0.0417 | 0.8204 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.0498 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0036 | 0.0417 | 0.0417 |
Brugia malayi | tubulin alpha-2 chain | 0.0036 | 0.0417 | 0.1559 |
Loa Loa (eye worm) | tubulin beta chain | 0.0019 | 0.013 | 0.0543 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0019 | 0.013 | 0.013 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Toxoplasma gondii | alpha tubulin TUBA1 | 0.0036 | 0.0417 | 0.0417 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0068 | 0.0982 | 0.4091 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0044 | 0.0562 | 0.0562 |
Trypanosoma brucei | pteridine reductase 1 | 0.004 | 0.0487 | 0.4956 |
Plasmodium vivax | tubulin alpha chain, putative | 0.0036 | 0.0417 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1589 | 0.6617 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.004 | 0.0487 | 0.0487 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0363 | 0.1327 |
Schistosoma mansoni | alpha tubulin | 0.0036 | 0.0417 | 0.1313 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0044 | 0.0562 | 0.183 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0068 | 0.0982 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0036 | 0.0417 | 0.0417 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0085 | 0.0146 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0036 | 0.0417 | 0.0417 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0036 | 0.0417 | 0.1313 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.0946 | 0.3808 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Trypanosoma brucei | beta tubulin | 0.0019 | 0.013 | 0.1327 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0618 | 0.2412 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0019 | 0.0121 | 0.0748 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0019 | 0.013 | 0.0284 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0618 | 0.2031 |
Brugia malayi | tubulin alpha chain - mouse | 0.0036 | 0.0417 | 0.1559 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0019 | 0.0121 | 0.123 |
Giardia lamblia | Multidrug resistance-associated protein 1 | 0.0015 | 0.0051 | 0.0046 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Echinococcus multilocularis | tubulin alpha chain | 0.0036 | 0.0417 | 0.1313 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0019 | 0.013 | 0.013 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0025 | 0.0228 | 0.0228 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0039 | 0.0483 | 0.1546 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0036 | 0.0417 | 0.0417 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0245 | 0.0823 |
Loa Loa (eye worm) | alpha-tubulin | 0.0036 | 0.0417 | 0.1738 |
Trypanosoma brucei | multidrug resistance protein E | 0.0015 | 0.0051 | 0.052 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0363 | 0.1118 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0487 | 0.2028 |
Echinococcus granulosus | tubulin alpha chain | 0.0036 | 0.0417 | 0.1313 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0585 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.0946 | 0.3207 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Echinococcus granulosus | peroxisome assembly protein 26 | 0.0036 | 0.0417 | 0.1313 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.0036 | 0.0417 | 0.1313 |
Brugia malayi | RNA binding protein | 0.0066 | 0.0946 | 0.3808 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.004 | 0.0487 | 0.1854 |
Trypanosoma brucei | multidrug resistance-associated protein, putative | 0.0015 | 0.0051 | 0.052 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.004 | 0.0487 | 0.1561 |
Plasmodium falciparum | alpha tubulin 1 | 0.0036 | 0.0417 | 0.0291 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0026 | 0.0242 | 0.2052 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0036 | 0.0417 | 0.1313 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0019 | 0.0121 | 0.0748 |
Echinococcus granulosus | tubulin alpha | 0.0019 | 0.013 | 0.0284 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0618 | 0.2031 |
Entamoeba histolytica | tubulin gamma chain | 0.0019 | 0.013 | 0.085 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.004 | 0.0487 | 0.2028 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0036 | 0.0417 | 0.1313 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0068 | 0.0982 | 1 |
Echinococcus granulosus | beta tubulin | 0.0019 | 0.013 | 0.0284 |
Trypanosoma cruzi | tubulin gamma chain | 0.0019 | 0.013 | 0.085 |
Schistosoma mansoni | tubulin subunit gamma | 0.0019 | 0.013 | 0.0284 |
Entamoeba histolytica | hypothetical protein | 0.0026 | 0.0242 | 0.2052 |
Echinococcus multilocularis | tubulin subunit TubB | 0.0036 | 0.0417 | 0.1313 |
Trypanosoma brucei | alpha tubulin | 0.0036 | 0.0417 | 0.4249 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0245 | 0.2077 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0019 | 0.0121 | 0.0755 |
Trypanosoma brucei | epsilon tubulin | 0.0019 | 0.013 | 0.1327 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0363 | 0.1118 |
Toxoplasma gondii | FATC domain-containing protein | 0.0026 | 0.0242 | 0.0242 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0363 | 0.1118 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Loa Loa (eye worm) | tubulin alpha-3 chain | 0.0025 | 0.0228 | 0.095 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Schistosoma mansoni | tubulin subunit beta | 0.0019 | 0.013 | 0.0284 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0019 | 0.013 | 0.0284 |
Giardia lamblia | GTOR | 0.0019 | 0.0121 | 0.1598 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0036 | 0.0417 | 0.0417 |
Entamoeba histolytica | tubulin family protein | 0.0019 | 0.013 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1021 | 0.4254 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0019 | 0.0121 | 0.123 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0618 | 0.2574 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Loa Loa (eye worm) | tubulin beta-2A chain | 0.0019 | 0.013 | 0.0543 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.0036 | 0.0417 | 0.1313 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0068 | 0.0982 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0149 | 0.2401 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0363 | 0.1118 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0245 | 0.0116 |
Trypanosoma brucei | tubulin gamma chain | 0.0019 | 0.013 | 0.1327 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Entamoeba histolytica | tubulin alpha chain, putative | 0.0036 | 0.0417 | 0.3933 |
Onchocerca volvulus | 0.004 | 0.0487 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0363 | 0.1118 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0036 | 0.0417 | 0.0417 |
Schistosoma mansoni | tubulin subunit alpha | 0.0036 | 0.0417 | 0.1313 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0044 | 0.0562 | 0.0562 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0044 | 0.0562 | 0.0562 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0618 | 0.2031 |
Echinococcus granulosus | beta tubulin | 0.0019 | 0.013 | 0.0284 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0272 | 0.1133 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0039 | 0.0483 | 0.1546 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0068 | 0.0982 | 0.3963 |
Echinococcus granulosus | tubulin epsilon chain | 0.0019 | 0.013 | 0.0284 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.0946 | 0.3808 |
Echinococcus granulosus | tubulin alpha chain | 0.0036 | 0.0417 | 0.1313 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0228 | 0.095 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0019 | 0.0121 | 0.0296 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0019 | 0.0121 | 0.025 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Brugia malayi | Tubulin beta-1 chain | 0.0019 | 0.013 | 0.0337 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0036 | 0.0417 | 0.0417 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0068 | 0.0982 | 0.3337 |
Trypanosoma brucei | alpha tubulin | 0.0036 | 0.0417 | 0.4249 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0019 | 0.0121 | 0.0748 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0036 | 0.0417 | 0.1313 |
Toxoplasma gondii | ABC transporter transmembrane region domain-containing protein | 0.0015 | 0.0051 | 0.0051 |
Echinococcus multilocularis | tubulin alpha chain | 0.0036 | 0.0417 | 0.1313 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0044 | 0.0562 | 0.0437 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0363 | 0.1512 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0019 | 0.013 | 0.0284 |
Schistosoma mansoni | tubulin subunit beta | 0.0019 | 0.013 | 0.0284 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0245 | 0.2077 |
Loa Loa (eye worm) | tubulin beta-1 chain | 0.0019 | 0.013 | 0.0543 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0051 | 0.0213 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.004 | 0.0487 | 0.1561 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0026 | 0.0242 | 0.2466 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0019 | 0.0121 | 0.025 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0036 | 0.0417 | 0.1313 |
Trypanosoma cruzi | alpha tubulin, putative | 0.0036 | 0.0417 | 0.3933 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0022 | 0.018 | 0.1381 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.004 | 0.0487 | 0.1854 |
Trypanosoma brucei | multidrug resistance-associated protein, putative | 0.0015 | 0.0051 | 0.052 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0016 | 0.0083 | 0.0345 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0068 | 0.0982 | 0.3337 |
Echinococcus granulosus | tubulin subunit TubB | 0.0036 | 0.0417 | 0.1313 |
Brugia malayi | Tubulin alpha-2 chain | 0.0036 | 0.0417 | 0.1559 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.1021 | 0.3477 |
Trypanosoma brucei | beta tubulin | 0.0019 | 0.013 | 0.1327 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.1589 | 0.6543 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.0946 | 0.394 |
Trypanosoma brucei | epsilon tubulin | 0.0019 | 0.013 | 0.1327 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0019 | 0.013 | 0.013 |
Schistosoma mansoni | tubulin subunit beta | 0.0019 | 0.013 | 0.0284 |
Schistosoma mansoni | tubulin subunit beta | 0.0019 | 0.013 | 0.0284 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0019 | 0.013 | 0.013 |
Loa Loa (eye worm) | ABC transporter transmembrane region family protein | 0.0015 | 0.0051 | 0.0213 |
Schistosoma mansoni | tubulin subunit alpha | 0.0036 | 0.0417 | 0.1313 |
Giardia lamblia | MRP-like ABC transporter | 0.0015 | 0.0051 | 0.0046 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0019 | 0.0121 | 0.123 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.004 | 0.0487 | 0.0361 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Echinococcus granulosus | geminin | 0.0174 | 0.2842 | 1 |
Entamoeba histolytica | tubulin alpha-1 chain | 0.0036 | 0.0417 | 0.3933 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.0019 | 0.013 | 0.085 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0019 | 0.0121 | 0.123 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0363 | 0.1327 |
Loa Loa (eye worm) | oxidoreductase | 0.004 | 0.0487 | 0.2028 |
Trypanosoma brucei | beta tubulin | 0.0019 | 0.013 | 0.1327 |
Trypanosoma brucei | oxidoreductase-like protein | 0.004 | 0.0487 | 0.4956 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0585 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Echinococcus granulosus | tubulin subunit beta | 0.0019 | 0.013 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.2842 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0363 | 0.1118 |
Loa Loa (eye worm) | alpha-tubulin isotype 2 | 0.0027 | 0.0272 | 0.1133 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.004 | 0.0487 | 0.0487 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Echinococcus multilocularis | peroxisome assembly protein 26 | 0.0036 | 0.0417 | 0.1313 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.1589 | 0.6617 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Brugia malayi | beta-tubulin, identical | 0.0019 | 0.013 | 0.0337 |
Echinococcus granulosus | tubulin alpha chain | 0.0036 | 0.0417 | 0.1313 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0019 | 0.013 | 0.013 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0019 | 0.0121 | 0.0748 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0019 | 0.013 | 0.013 |
Echinococcus granulosus | tubulin gamma 1 chain | 0.0019 | 0.013 | 0.0284 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0242 | 0.0242 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.004 | 0.0487 | 0.4679 |
Trypanosoma brucei | alpha tubulin | 0.0036 | 0.0417 | 0.4249 |
Brugia malayi | Tubulin alpha chain | 0.0036 | 0.0417 | 0.1559 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0946 | 0.3207 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0026 | 0.0242 | 0.0685 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0026 | 0.0242 | 0.0813 |
Leishmania major | gamma-tubulin | 0.0019 | 0.013 | 0.085 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0149 | 0.2401 | 0.8421 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0019 | 0.0121 | 0.0755 |
Echinococcus multilocularis | beta tubulin | 0.0019 | 0.013 | 0.0284 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0027 | 0.0272 | 0.1133 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.004 | 0.0487 | 0.0361 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0019 | 0.0121 | 0.0296 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Schistosoma mansoni | tubulin subunit beta | 0.0019 | 0.013 | 0.0284 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0946 | 0.3207 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0068 | 0.0982 | 1 |
Schistosoma mansoni | alpha tubulin | 0.0036 | 0.0417 | 0.1313 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0618 | 0.2031 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.004 | 0.0487 | 0.4956 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.004 | 0.0487 | 0.4679 |
Echinococcus multilocularis | geminin | 0.0174 | 0.2842 | 1 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0068 | 0.0982 | 1 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.004 | 0.0487 | 0.4679 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0051 | 0.0213 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0585 | 1 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0019 | 0.0121 | 0.0503 |
Onchocerca volvulus | 0.004 | 0.0487 | 0.5 | |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0036 | 0.0417 | 0.1313 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.004 | 0.0487 | 0.4679 |
Loa Loa (eye worm) | acetyltransferase | 0.0149 | 0.2401 | 1 |
Trypanosoma cruzi | beta tubulin, putative | 0.0019 | 0.013 | 0.085 |
Trypanosoma brucei | p-glycoprotein | 0.0015 | 0.0051 | 0.052 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.2842 | 1 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0149 | 0.2401 | 0.8421 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0019 | 0.013 | 0.0284 |
Toxoplasma gondii | beta-1 tubulin, putative | 0.0019 | 0.013 | 0.013 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0019 | 0.013 | 0.013 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Trichomonas vaginalis | hypothetical protein | 0.0585 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0618 | 0.2031 |
Brugia malayi | Tubulin gamma chain | 0.0019 | 0.013 | 0.0337 |
Echinococcus multilocularis | tubulin alpha chain | 0.0036 | 0.0417 | 0.1313 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.0946 | 0.394 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0036 | 0.0417 | 0.1738 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0019 | 0.0121 | 0.025 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.0036 | 0.0417 | 0.1313 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0019 | 0.0121 | 0.0748 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.004 | 0.0487 | 0.2028 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.0498 | 0.0373 |
Echinococcus multilocularis | tubulin alpha chain | 0.0036 | 0.0417 | 0.1313 |
Echinococcus multilocularis | tubulin subunit beta | 0.0019 | 0.013 | 0.0284 |
Toxoplasma gondii | alpha-tubulin I, putative | 0.0036 | 0.0417 | 0.0417 |
Leishmania major | oxidoreductase-like protein | 0.004 | 0.0487 | 0.4679 |
Echinococcus multilocularis | tubulin alpha | 0.0019 | 0.013 | 0.0284 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0019 | 0.013 | 0.0284 |
Trypanosoma brucei | epsilon tubulin | 0.0019 | 0.013 | 0.1327 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.1589 | 0.6543 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0019 | 0.0121 | 0.123 |
Brugia malayi | alpha-tubulin | 0.0036 | 0.0417 | 0.1559 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0145 | 0.2328 | 0.8159 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.004 | 0.0487 | 0.4679 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.018 | 0.0748 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0946 | 0.3207 |
Loa Loa (eye worm) | beta-tubulin | 0.0019 | 0.013 | 0.0543 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0036 | 0.0417 | 0.1313 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0036 | 0.0417 | 0.1313 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Loa Loa (eye worm) | tubulin alpha-2 chain | 0.0036 | 0.0417 | 0.1738 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Giardia lamblia | Multidrug resistance-associated protein 1 | 0.0015 | 0.0051 | 0.0046 |
Echinococcus granulosus | alpha tubulin | 0.0036 | 0.0417 | 0.1313 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Loa Loa (eye worm) | tubulin gamma chain | 0.0019 | 0.013 | 0.0543 |
Schistosoma mansoni | tubulin subunit epsilon | 0.0019 | 0.013 | 0.0284 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0585 | 1 | 1 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0036 | 0.0417 | 0.1313 |
Plasmodium vivax | tubulin alpha chain, putative | 0.0036 | 0.0417 | 0.0291 |
Loa Loa (eye worm) | tubulin beta-4 chain | 0.0019 | 0.013 | 0.0543 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0618 | 0.2031 |
Echinococcus multilocularis | tubulin epsilon chain | 0.0019 | 0.013 | 0.0284 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0245 | 0.0245 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0019 | 0.0121 | 0.0748 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.0946 | 0.394 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Entamoeba histolytica | tubulin family protein | 0.0019 | 0.013 | 0.085 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0027 | 0.0272 | 0.1133 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.0036 | 0.0417 | 0.1313 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0019 | 0.0121 | 0.025 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0019 | 0.013 | 0.0284 |
Loa Loa (eye worm) | BEN-1 protein | 0.0019 | 0.013 | 0.0543 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0036 | 0.0417 | 0.1738 |
Schistosoma mansoni | tubulin subunit beta | 0.0019 | 0.013 | 0.0284 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0068 | 0.0982 | 0.3337 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0019 | 0.0121 | 0.0748 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0363 | 0.1118 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0019 | 0.013 | 0.0284 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.0019 | 0.013 | 0.085 |
Echinococcus granulosus | tubulin alpha chain | 0.0036 | 0.0417 | 0.1313 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.0121 | 0.0121 |
Echinococcus granulosus | tubulin beta 4A class IVa | 0.0019 | 0.013 | 0.0284 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0019 | 0.0121 | 0.025 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.0946 | 0.3207 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Schistosoma mansoni | alpha tubulin | 0.0036 | 0.0417 | 0.1313 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0417 | 0.1738 |
Giardia lamblia | ABC transporter, putative | 0.0015 | 0.0051 | 0.0046 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0946 | 0.3207 |
Echinococcus multilocularis | tubulin gamma 1 chain | 0.0019 | 0.013 | 0.0284 |
Plasmodium falciparum | alpha tubulin 2 | 0.0036 | 0.0417 | 0.0291 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0019 | 0.0121 | 0.0748 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.004 | 0.0487 | 0.4679 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0019 | 0.013 | 0.013 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.0498 | 0.48 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0019 | 0.013 | 0.0284 |
Toxoplasma gondii | beta tubulin | 0.0019 | 0.013 | 0.013 |
Leishmania major | alpha tubulin | 0.0036 | 0.0417 | 0.3933 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0363 | 0.1118 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0585 | 1 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0363 | 0.1118 |
Giardia lamblia | Alpha-tubulin | 0.0036 | 0.0417 | 0.8204 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0245 | 0.0116 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0946 | 0.3207 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.004 | 0.0487 | 0.0487 |
Leishmania major | pteridine reductase 1 | 0.004 | 0.0487 | 0.4679 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0019 | 0.0121 | 0.0748 |
Trichomonas vaginalis | tubulin, putative | 0.0019 | 0.013 | 0.013 |
Giardia lamblia | Beta tubulin | 0.0019 | 0.013 | 0.181 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0036 | 0.0417 | 0.1313 |
Leishmania major | beta tubulin | 0.0019 | 0.013 | 0.085 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis | ChEMBL. | 24363888 | |
IC50 (binding) | = 125 uM | Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis | ChEMBL. | 24363888 |
MIC (functional) | = 200 uM | Antibacterial activity against Escherichia coli assessed as complete growth inhibition after 24 hrs by standard microdilution assay | ChEMBL. | 24363888 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.