Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | oxidoreductase | 0.0012 | 0.0126 | 0.0069 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0016 | 0.026 | 0.024 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0258 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0609 | 0.0555 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.0538 | 0.0734 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0025 | 0.0538 | 0.0938 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.1274 | 1 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0181 | 0.5733 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0119 | 0.3663 | 0.6309 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0383 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0107 | 0.3267 | 0.5699 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0012 | 0.0118 | 0.0061 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0016 | 0.0258 | 0.0235 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0609 | 0.0862 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0016 | 0.026 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0309 | 1 | 1 |
Onchocerca volvulus | 0.0012 | 0.0126 | 0.0604 | |
Mycobacterium ulcerans | thioesterase | 0.0021 | 0.0401 | 0.0491 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0383 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0309 | 1 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0383 | 0.0328 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0037 | 0.0943 | 0.1644 |
Onchocerca volvulus | 0.0023 | 0.0484 | 0.375 | |
Brugia malayi | hypothetical protein | 0.0017 | 0.0293 | 0.0238 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0258 | 0.1148 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0025 | 0.0538 | 0.0483 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0258 | 0.1148 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0107 | 0.3267 | 0.5699 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0012 | 0.0126 | 0.0219 |
Echinococcus granulosus | muscleblind protein | 0.0309 | 1 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0609 | 0.4207 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0383 | 0.0668 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0012 | 0.0126 | 0.0069 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0024 | 0.0512 | 0.0894 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0021 | 0.0401 | 0.0491 |
Onchocerca volvulus | 0.0012 | 0.0126 | 0.0604 | |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0258 | 0.0202 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0258 | 0.1148 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0107 | 0.3267 | 0.5699 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0383 | 0.0458 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0258 | 0.0235 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0016 | 0.0258 | 0.1148 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0014 | 0.0184 | 0.0321 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0037 | 0.0943 | 0.1457 |
Leishmania major | trypanothione reductase | 0.0047 | 0.1274 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0107 | 0.3267 | 0.5699 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1223 | 0.2523 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0016 | 0.0258 | 0.0449 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0126 | 0.0069 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0383 | 0.0458 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0181 | 0.5733 | 1 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0012 | 0.0114 | 0.0058 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0018 | 0.0307 | 0.0535 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0258 | 0.0235 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0609 | 0.4207 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1223 | 0.1173 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0484 | 0.0429 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0026 | 0.0588 | 0.0825 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0383 | 0.2238 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.1274 | 0.2048 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0119 | 0.3663 | 0.639 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0012 | 0.0132 | 0.0012 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0026 | 0.0588 | 0.0825 |
Trichomonas vaginalis | hypothetical protein | 0.0181 | 0.5733 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0012 | 0.0126 | 0.0069 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0258 | 0.1148 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0258 | 0.0202 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0026 | 0.0588 | 0.1026 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0609 | 0.4207 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0258 | 0.0235 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0012 | 0.0126 | 0.0069 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0119 | 0.3663 | 0.639 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0025 | 0.0538 | 0.0938 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.002 | 0.0377 | 0.0449 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0383 | 1 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0026 | 0.0588 | 0.1026 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0016 | 0.0258 | 0.1148 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0025 | 0.0538 | 0.0938 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0258 | 0.1148 |
Brugia malayi | glutathione reductase | 0.0047 | 0.1274 | 0.1224 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0609 | 0.0555 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0012 | 0.0126 | 0.0069 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0258 | 0.0235 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0012 | 0.0126 | 0.0219 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0021 | 0.0401 | 0.0699 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0258 | 0.0235 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.1274 | 0.1224 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.002 | 0.0388 | 0.0677 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0012 | 0.0126 | 0.0219 |
Echinococcus multilocularis | muscleblind protein | 0.0309 | 1 | 1 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0012 | 0.0126 | 0.0219 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0383 | 0.0458 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1223 | 0.1173 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0383 | 0.2238 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0181 | 0.5733 | 1 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0025 | 0.0538 | 0.0734 |
Onchocerca volvulus | 0.0043 | 0.1144 | 0.9553 | |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0383 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0016 | 0.0258 | 0.0235 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0383 | 0.0229 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1223 | 0.2523 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0023 | 0.0484 | 0.0844 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0258 | 0.1148 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0023 | 0.0484 | 0.0429 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.1274 | 0.1224 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0258 | 0.0235 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0383 | 0.0458 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1223 | 0.1173 |
Schistosoma mansoni | dihydropteridine reductase | 0.0012 | 0.0126 | 0.0149 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0016 | 0.0258 | 0.1148 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0181 | 0.5733 | 1 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.0538 | 0.0734 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0258 | 0.1148 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0044 | 0.1195 | 1 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0181 | 0.5733 | 1 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0016 | 0.0258 | 0.0235 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.1274 | 0.2223 |
Loa Loa (eye worm) | fatty acid synthase | 0.0024 | 0.0527 | 0.0472 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0026 | 0.0588 | 0.0825 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0383 | 0.2238 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0177 | 0.0121 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.1274 | 0.2048 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.1274 | 0.1224 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0609 | 0.0862 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0383 | 0.2238 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.1274 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0012 | 0.0126 | 0.0219 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0037 | 0.0943 | 0.1457 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.0538 | 0.0734 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0258 | 0.1148 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0012 | 0.0126 | 0.0219 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0025 | 0.0538 | 0.0734 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0383 | 0.0705 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0107 | 0.3267 | 0.5603 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.1274 | 0.2048 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0258 | 0.0235 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0258 | 0.1148 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0119 | 0.3663 | 0.639 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.002 | 0.0377 | 0.0449 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0012 | 0.0114 | 0.0058 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0609 | 0.0862 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0037 | 0.0943 | 0.1644 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0016 | 0.0258 | 0.1148 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.1274 | 0.2048 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0012 | 0.0126 | 0.0219 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0181 | 0.5733 | 1 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0016 | 0.0258 | 0.1148 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0016 | 0.0258 | 0.0235 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.002 | 0.0377 | 0.0449 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0258 | 0.0202 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1223 | 0.1173 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.001 | 0.005 | 0.0087 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0258 | 0.0235 |
Mycobacterium ulcerans | polyketide synthase | 0.0026 | 0.0588 | 0.0825 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1223 | 0.2523 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0258 | 0.1148 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0012 | 0.0118 | 0.0061 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0016 | 0.025 | 0.0221 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0012 | 0.0126 | 0.0069 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0012 | 0.0126 | 0.0069 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0181 | 0.5733 | 1 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0026 | 0.0588 | 0.1026 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0026 | 0.0588 | 0.0825 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0258 | 0.0434 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0309 | 1 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0107 | 0.3267 | 0.5699 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0018 | 0.0301 | 0.0313 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0026 | 0.0588 | 0.0825 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0012 | 0.0126 | 0.0219 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0047 | 0.1271 | 0.1221 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0026 | 0.0588 | 0.0825 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0118 | 0.0132 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.1274 | 0.1224 |
Loa Loa (eye worm) | acyl carrier protein | 0.0011 | 0.0095 | 0.0038 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0258 | 0.0235 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0258 | 0.1148 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0383 | 0.0229 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1223 | 0.1173 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0181 | 0.5733 | 1 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0383 | 0.0705 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0383 | 0.0328 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.1274 | 0.1224 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0609 | 0.4207 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0025 | 0.0538 | 0.0734 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0258 | 0.1148 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0024 | 0.0512 | 0.0894 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0016 | 0.026 | 0.024 |
Mycobacterium ulcerans | polyketide synthase | 0.0025 | 0.0538 | 0.0734 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.1274 | 0.2048 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0383 | 0.0458 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1223 | 0.1173 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0609 | 0.0862 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0012 | 0.0126 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1094 | 0.1043 |
Mycobacterium ulcerans | thioesterase TesA | 0.0021 | 0.0401 | 0.0491 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0012 | 0.0126 | 0.0149 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0107 | 0.3267 | 0.5699 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0383 | 0.0328 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.