Detailed information for compound 566384

Basic information

Technical information
  • TDR Targets ID: 566384
  • Name: [(2E)-3,7-dimethylocta-2,6-dienyl] (4E,8E)-5, 9,13-trimethyltetradeca-4,8,12-trienoate
  • MW: 400.637 | Formula: C27H44O2
  • H donors: 0 H acceptors: 1 LogP: 9.08 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 1
  • SMILES: C/C(=C\CCC(=O)OC/C=C(/CCC=C(C)C)\C)/CC/C=C(/CCC=C(C)C)\C
  • InChi: 1S/C27H44O2/c1-22(2)12-8-14-24(5)16-10-17-25(6)18-11-19-27(28)29-21-20-26(7)15-9-13-23(3)4/h12-13,16,18,20H,8-11,14-15,17,19,21H2,1-7H3/b24-16+,25-18+,26-20+
  • InChiKey: ZPACYDRSPFRDHO-ROBAGEODSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (4E,8E)-5,9,13-trimethyltetradeca-4,8,12-trienoic acid [(2E)-3,7-dimethylocta-2,6-dienyl] ester
  • Gefarnate
  • [(2E)-3,7-dimethylocta-2,6-dienyl] 5,9,13-trimethyltetradeca-4,8,12-trienoate
  • 3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-trienoate
  • 5,9,13-trimethyltetradeca-4,8,12-trienoic acid [(2E)-3,7-dimethylocta-2,6-dienyl] ester
  • 5,9,13-trimethyltetradeca-4,8,12-trienoic acid 3,7-dimethylocta-2,6-dienyl ester
  • 30462-47-6
  • 51-77-4
  • 16898-88-7
  • NSC138947
  • Osteol
  • (E,E,E)-5,9,13-Trimethyl-4,8,12-tetradecatrienoic acid 3,7-dimethyl-2,6-octadienyl ester
  • 4,8,12-Tetradecatrienoic acid, 5,9,13-trimethyl-, (2E)-3,7-dimethyl-2,6-octadienyl ester, (4E,8E)-
  • 4,8,12-Tetradecatrienoic acid, 5,9,13-trimethyl-, 3,7-dimethyl-2,6-octadienyl ester, (E,E,E)-
  • DA-688
  • EINECS 200-121-0
  • GEFAMATE
  • Gefarnate [BAN:INN:JAN]
  • Gefarnato [INN-Spanish]
  • Gefarnatum [INN-Latin]
  • Gefarnil
  • Gefarnyl
  • Geranyl farnesylacetate
  • trans-3,7-Dimethyl-2,6-octadienyl 5,9,13-trimethyl-4,8,12-tetradecatrienoate
  • 3,7-Dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-enoate
  • EINECS 240-942-1
  • 5,9,13-Trimethyl-4,8,12-tetradecatrienoic acid 3,7-dimethyl-2,6-octadienyl ester
  • AIDS-001614
  • AIDS001614

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis neuropeptide s receptor 0.0031 0.0206 0.0206
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0437 0.1002
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0117 0.0268
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0614 0.1273
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0013 0.0027
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0206 0.0428
Echinococcus multilocularis survival motor neuron protein 1 0.0235 0.276 0.276
Onchocerca volvulus 0.0031 0.0206 0.0751
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0065 0.0628 0.0628
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0206 0.0231
Schistosoma mansoni hypothetical protein 0.0166 0.19 0.3941
Trichomonas vaginalis set domain proteins, putative 0.0234 0.2747 0.6298
Loa Loa (eye worm) glutamate receptor 0.0052 0.0476 0.0988
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0206 0.0206
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0106 0.1143 0.3245
Brugia malayi follicle stimulating hormone receptor 0.0031 0.0206 0.0748
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0016 0.0013 0.0167
Brugia malayi G protein-coupled receptor F59B2.13 0.0031 0.0206 0.0748
Loa Loa (eye worm) hypothetical protein 0.0049 0.0437 0.0906
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0391 0.081
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.003
Onchocerca volvulus Huntingtin homolog 0.012 0.1324 0.4819
Brugia malayi Serotonin receptor 0.0031 0.0206 0.0748
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0281 0.0365
Brugia malayi Cytochrome P450 family protein 0.0046 0.0391 0.1415
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0408 0.0408
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0031 0.0206 0.0428
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0089 0.0988
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Schistosoma mansoni hypothetical protein 0.0035 0.0263 0.0546
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0206 0.0231
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0437 0.1002
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0016 0.0013 0.0027
Schistosoma mansoni biogenic amine receptor 0.0031 0.0206 0.0428
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Brugia malayi ORL1-like opioid receptor 0.0031 0.0206 0.0748
Brugia malayi hypothetical protein 0.0235 0.276 1
Trichomonas vaginalis ran, putative 0.0022 0.0089 0.0204
Brugia malayi cytosol aminopeptidase 0.0021 0.0082 0.0299
Loa Loa (eye worm) hypothetical protein 0.0037 0.0281 0.0582
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0437 0.1583
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0783 0.0876
Brugia malayi RNA binding protein 0.0063 0.0614 0.2224
Echinococcus granulosus 7TM GPCR rhodopsin 0.0031 0.0206 0.0231
Onchocerca volvulus 0.0031 0.0206 0.0751
Echinococcus multilocularis leucyl aminopeptidase 0.0021 0.0082 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0206 0.0428
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0016 0.0013 0.0037
Onchocerca volvulus 0.0031 0.0206 0.0751
Mycobacterium ulcerans hypothetical protein 0.0049 0.0437 0.1002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0126 0.0261
Leishmania major pteridine reductase 1 0.0025 0.0126 0.0358
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0013 0.0037
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0149 0.0342
Brugia malayi CCR4 0.0016 0.0013 0.0047
Trichomonas vaginalis Phospholipase C precursor, putative 0.0016 0.0013 0.003
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0013 0.0037
Echinococcus multilocularis snurportin 1 0.0313 0.3745 0.3745
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0281 0.0643
Schistosoma mansoni hypothetical protein 0.0031 0.0206 0.0428
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0089 0.0204
Schistosoma mansoni myosin xvIII 0.0031 0.0206 0.0428
Brugia malayi AKH receptor 0.0031 0.0206 0.0748
Brugia malayi Importin beta-1 subunit 0.0029 0.0186 0.0675
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0031 0.0206 0.0748
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0025 0.0126 0.0289
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0031 0.0206 0.0428
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0016 0.0013 0.0037
Echinococcus granulosus tumor protein p63 0.0333 0.3996 0.4472
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.0167
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0437 0.1002
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0031 0.0206 0.0428
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0783 0.2221
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0031 0.0206 0.0748
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0149 0.0423
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0025 0.0126 0.161
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0206 0.0428
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0339 0.0963
Schistosoma mansoni opsin-like receptor 0.0031 0.0206 0.0428
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0025 0.0126 0.0141
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.0167
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0013 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.012 0.1324 0.2745
Brugia malayi putative neuropeptide receptor 0.0031 0.0206 0.0748
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0027
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0025 0.0126 0.0289
Schistosoma mansoni hypothetical protein 0.0047 0.0408 0.0846
Onchocerca volvulus 0.0031 0.0206 0.0751
Brugia malayi RE15519p 0.0031 0.0206 0.0748
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0016 0.0013 0.003
Brugia malayi hypothetical protein 0.0031 0.0206 0.0748
Schistosoma mansoni ran 0.0022 0.0089 0.0185
Echinococcus granulosus mitogen activated protein kinase 11 0.0127 0.1411 0.1579
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0016 0.0013 0.0015
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0089 0.0323
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0126 0.0289
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0408 0.0456
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0013 0.0047
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0206 0.0206
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0031 0.0206 0.0206
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0031 0.0206 0.0748
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0127 0.1411 0.4004
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0362 0.4361 1
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0013 0.0027
Echinococcus granulosus orexin receptor type 2 0.0031 0.0206 0.0231
Schistosoma mansoni synaptojanin 0.0016 0.0013 0.0027
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0149 0.0342
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0206 0.0428
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0206 0.0206
Echinococcus granulosus mitogen activated protein kinase 14 0.0127 0.1411 0.1579
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0025 0.0126 0.0289
Echinococcus granulosus flap endonuclease 1 0.0026 0.0149 0.0167
Schistosoma mansoni dihydropteridine reductase 0.0025 0.0126 0.0261
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0187 0.043
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0206 0.0428
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0126 0.0289
Echinococcus granulosus snurportin 1 0.0313 0.3745 0.4192
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0186 0.0528
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0206 0.0428
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0408 0.1478
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0025 0.0126 0.0358
Onchocerca volvulus 0.0025 0.0126 0.0459
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0126 0.0289
Echinococcus granulosus serotonin receptor 0.0031 0.0206 0.0231
Brugia malayi hypothetical protein 0.0031 0.0206 0.0748
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0437 0.1002
Echinococcus multilocularis synaptojanin 1 0.0016 0.0013 0.0013
Plasmodium falciparum DNase I-like protein, putative 0.0016 0.0013 0.003
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0021 0.0082 0.0171
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0021 0.0082 0.0234
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0339 0.0963
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0206 0.0206
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0016 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0027
Brugia malayi Serotonin receptor 0.0031 0.0206 0.0748
Echinococcus multilocularis GPCR, family 2 0.0047 0.0408 0.0408
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0187 0.0389
Plasmodium vivax importin-beta 2, putative 0.0029 0.0186 0.0427
Schistosoma mansoni hypothetical protein 0.0031 0.0206 0.0428
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.003
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0408 0.1478
Schistosoma mansoni hypothetical protein 0.0047 0.0408 0.0846
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0126 0.0289
Schistosoma mansoni synaptojanin 0.0016 0.0013 0.0027
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0013 0.0027
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0437 0.1002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0016 0.0013 0.0037
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0783 0.2221
Brugia malayi G-protein coupled receptor 0.0031 0.0206 0.0748
Brugia malayi metabotropic glutamate receptor type 2 0.0026 0.0139 0.0504
Brugia malayi G-protein coupled receptor 0.0031 0.0206 0.0748
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0031 0.0206 0.0231
Brugia malayi Dopamine receptor protein 1 0.0031 0.0206 0.0748
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0437 0.1002
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0206 0.0231
Mycobacterium ulcerans hypothetical protein 0.0156 0.177 0.4059
Brugia malayi Pre-SET motif family protein 0.0205 0.2391 0.8664
Schistosoma mansoni leucine aminopeptidase 0.0021 0.0082 0.0171
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0016 0.0013 0.0013
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0025 0.0126 0.0289
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0206 0.0428
Loa Loa (eye worm) hypothetical protein 0.0399 0.4822 1
Loa Loa (eye worm) glutamate receptor 0.0021 0.0077 0.016
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0025 0.0126 0.0358
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.003
Trypanosoma brucei RNA editing exonuclease 2 0.0016 0.0013 0.0037
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0126 0.0289
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0031 0.0206 0.0428
Echinococcus granulosus survival motor neuron protein 1 0.0235 0.276 0.3089
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0187 0.0187
Echinococcus granulosus traf and tnf receptor associated protein 0.0016 0.0013 0.0015
Echinococcus multilocularis mitogen activated protein kinase 14 0.0127 0.1411 0.1411
Onchocerca volvulus 0.0031 0.0206 0.0751
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0013 0.0037
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0013 0.0037
Echinococcus multilocularis mitogen activated protein kinase 14 0.0127 0.1411 0.1411
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0206 0.0206
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0437 0.1002
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0149 0.0149
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0089 0.0204
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0025 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0399 0.4822 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.1681 0.6091
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0018 0.0038 0.0109
Entamoeba histolytica hypothetical protein 0.0035 0.0263 0.3362
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0418 0.1516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0206 0.0428
Loa Loa (eye worm) melatonin receptor type 1A 0.0031 0.0206 0.0428
Onchocerca volvulus 0.0031 0.0206 0.0751
Onchocerca volvulus 0.0025 0.0126 0.0459
Schistosoma mansoni amine GPCR 0.0031 0.0206 0.0428
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0127 0.1411 0.4004
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0016 0.0013 0.0015
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0016 0.0013 0.003
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0013 0.0037
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0206 0.0206
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.0167
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0025 0.0126 0.0358
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0025 0.0126 0.0289
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0031 0.0206 0.0206
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0021 0.0082 0.0234
Schistosoma mansoni flap endonuclease-1 0.0024 0.0117 0.0243
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0206 0.0206
Trypanosoma brucei pteridine reductase 1 0.0025 0.0126 0.0358
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0013 0.003
Onchocerca volvulus 0.0049 0.0437 0.1591
Loa Loa (eye worm) retinol dehydrogenase 12 0.0025 0.0126 0.0261
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0025 0.0126 0.0261
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0031 0.0206 0.0231
Schistosoma mansoni neutral sphingomyelinase 0.0016 0.0013 0.0027
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0127 0.1411 0.4004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0255 0.0585
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.3524 1
Echinococcus granulosus neuropeptide receptor 0.0031 0.0206 0.0231
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0025 0.0126 0.0289
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0783 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0281 0.0582
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0027
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0281 0.0643
Onchocerca volvulus 0.0234 0.2747 1
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0021 0.0082 0.0234
Echinococcus multilocularis somatostatin receptor 0.0031 0.0206 0.0206
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0031 0.0206 0.0206
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0408 0.0408
Onchocerca volvulus 0.0029 0.0187 0.0682
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0206 0.0206
Trypanosoma brucei oxidoreductase-like protein 0.0025 0.0126 0.0358
Echinococcus multilocularis leucyl aminopeptidase 0.0021 0.0082 0.0082
Schistosoma mansoni survival motor neuron protein 0.0048 0.0418 0.0868
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0013 0.0047
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0013 0.0047
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0206 0.0428
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0016 0.0013 0.0037
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0089 0.01
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0089 0.0089
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0614 0.1273
Echinococcus granulosus alpha 1A adrenergic receptor 0.0031 0.0206 0.0231
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0082 0.0299
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1572 0.4461
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0206 0.0231
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0614 0.1273
Echinococcus granulosus sex peptide receptor 0.0031 0.0206 0.0231
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Onchocerca volvulus 0.0031 0.0206 0.0751
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0013 0.0037
Leishmania major RNA-editing complex protein MP100, putative 0.0016 0.0013 0.0037
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0783 0.1795
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0206 0.0231
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0021 0.0082 0.0092
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0437 0.1002
Schistosoma mansoni amine GPCR 0.0031 0.0206 0.0428
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0437 0.1583
Brugia malayi sulfakinin receptor protein 0.0031 0.0206 0.0748
Brugia malayi Tachykinin-like peptides receptor 99D 0.0031 0.0206 0.0748
Echinococcus granulosus g protein coupled receptor 0.0031 0.0206 0.0231
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0089 0.0204
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Onchocerca volvulus Putative neutral sphingomyelinase 0.0016 0.0013 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0206 0.0206
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0206 0.0206
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0437 0.5582
Loa Loa (eye worm) TYRA-2 protein 0.0031 0.0206 0.0428
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0206 0.0231
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0206 0.0206
Brugia malayi GnHR receptor homolog 0.0031 0.0206 0.0748
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0296 0.3524 1
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0149 0.0342
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0031 0.0206 0.0231
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0016 0.0013 0.003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.0167
Brugia malayi Pre-SET motif family protein 0.0029 0.0187 0.0679
Echinococcus multilocularis geminin 0.0166 0.19 0.19
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0089 0.0253
Onchocerca volvulus 0.0031 0.0206 0.0751
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0783 0.2221
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0187 0.0389
Schistosoma mansoni neuropeptide receptor 0.0031 0.0206 0.0428
Echinococcus multilocularis leucyl aminopeptidase 0.0021 0.0082 0.0082
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0025 0.0126 0.0358
Onchocerca volvulus 0.0031 0.0206 0.0751
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0013 0.003
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0362 0.4361 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0206 0.0428
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0437 0.5582
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0127 0.1411 0.2927
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0117 0.0268
Schistosoma mansoni biogenic amine receptor 0.0031 0.0206 0.0428
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0187 0.0187
Echinococcus granulosus G protein coupled receptor 139 0.0031 0.0206 0.0231
Onchocerca volvulus Neuropeptide F receptor homolog 0.0031 0.0206 0.0751
Mycobacterium tuberculosis Possible oxidoreductase 0.0025 0.0126 0.0289
Loa Loa (eye worm) hypothetical protein 0.0037 0.0281 0.0582
Echinococcus multilocularis traf and tnf receptor associated protein 0.0016 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0049 0.0437 0.0906
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0263 0.0263
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0149 0.0309
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0206 0.0428
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0206 0.0231
Echinococcus granulosus g protein coupled receptor 0.0031 0.0206 0.0231
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0021 0.0082 0.0234
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0206 0.0428
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0025 0.0126 0.0289
Brugia malayi hypothetical protein 0.0031 0.0206 0.0748
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0783 0.1623
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0437 0.1583
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0013 0.0037
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0187 0.0389
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0126 0.0289
Brugia malayi P38 map kinase family protein 2 0.0127 0.1411 0.5112
Echinococcus granulosus fmrfamide receptor 0.0031 0.0206 0.0231
Echinococcus granulosus g protein coupled receptor 0.0031 0.0206 0.0231
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0013 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0206 0.0206
Echinococcus multilocularis G-protein coupled receptor, putative 0.0031 0.0206 0.0206
Schistosoma mansoni carbon catabolite repressor protein 0.0016 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0149 0.1681 0.3487
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.1681 0.6091
Echinococcus granulosus somatostatin receptor 0.0031 0.0206 0.0231
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0206 0.0428
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0783 0.1795
Mycobacterium ulcerans leucyl aminopeptidase 0.0106 0.1143 0.2622
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0206 0.0231
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0339 0.0963
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0206 0.0231
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0437 0.1002
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0437 0.124
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0437 0.124
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Toxoplasma gondii exonuclease III APE 0.0077 0.0783 0.1795
Schistosoma mansoni nocturnin 0.0016 0.0013 0.0027
Echinococcus multilocularis serotonin receptor 0.0399 0.4822 0.4822
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0031 0.0206 0.0428
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Loa Loa (eye worm) hypothetical protein 0.0029 0.0186 0.0386
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0106 0.1143 0.2622
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0031 0.0206 0.0206
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.1335 0.2768
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0106 0.1143 0.3245
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0453 0.1287
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0013 0.0047
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Echinococcus granulosus g-protein coupled receptor 0.0031 0.0206 0.0231
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0025 0.0126 0.0289
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0021 0.0082 0.0234
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0783 0.1551
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0021 0.0082 0.0171
Schistosoma mansoni amine GPCR 0.0031 0.0206 0.0428
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0149 0.0423
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Echinococcus multilocularis serotonin receptor 0.0399 0.4822 0.4822
Schistosoma mansoni hypothetical protein 0.0047 0.0408 0.0846
Schistosoma mansoni metabotropic glutamate receptor 0.0026 0.0139 0.0288
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0149 0.0423
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0408 0.0456
Schistosoma mansoni neuropeptide f receptor 76f 0.0031 0.0206 0.0428
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0044 0.037 0.037
Onchocerca volvulus 0.0031 0.0206 0.0751
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0025 0.0126 0.0289
Loa Loa (eye worm) hypothetical protein 0.0037 0.0281 0.0582
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0362 0.4361 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0013 0.0167
Echinococcus multilocularis mitogen activated protein kinase 11 0.0127 0.1411 0.1411
Schistosoma mansoni biogenic amine (5HT) receptor 0.0399 0.4822 1
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0106 0.1143 0.2622
Loa Loa (eye worm) hypothetical protein 0.0037 0.0281 0.0582
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0187 0.0389
Toxoplasma gondii hypothetical protein 0.0048 0.0416 0.0954
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0313 0.3745 0.7768
Plasmodium falciparum flap endonuclease 1 0.0026 0.0149 0.0342
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0206 0.0428
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0013 0.0047
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0362 0.4361 1
Echinococcus multilocularis neutral sphingomyelinase 0.0016 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0048 0.0418 0.0868
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0106 0.1143 0.3245
Leishmania major hypothetical protein, conserved 0.0016 0.0013 0.0037
Schistosoma mansoni opsin-like receptor 0.0031 0.0206 0.0428
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0048 0.0414 0.1502
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0016 0.0013 0.0037
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0013 0.003
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0783 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0206 0.0231
Echinococcus granulosus allatostatin A receptor 0.0031 0.0206 0.0231
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0013 0.0027
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0235 0.276 0.5725
Echinococcus granulosus neuropeptide s receptor 0.0031 0.0206 0.0231
Plasmodium falciparum importin beta, putative 0.0029 0.0186 0.0427
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0614 0.1273
Leishmania major hypothetical protein, conserved 0.0016 0.0013 0.0037
Echinococcus granulosus metabotropic glutamate receptor 5 0.0065 0.0628 0.0703
Plasmodium vivax exodeoxyribonuclease III, putative 0.0016 0.0013 0.003
Echinococcus multilocularis neuropeptide FF receptor 2 0.0031 0.0206 0.0206
Schistosoma mansoni growth hormone secretagogue receptor 0.0031 0.0206 0.0428
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0206 0.0231
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0025 0.0126 0.0289
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0614 0.2224
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0255 0.0585
Echinococcus granulosus hypothetical protein 0.0727 0.8934 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0031 0.0206 0.0428
Echinococcus granulosus peptide allatostatin:somatostatin 0.0031 0.0206 0.0231
Leishmania major importin beta-1 subunit, putative 0.0024 0.0117 0.0331
Onchocerca volvulus 0.0031 0.0206 0.0751
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0281 0.0643
Onchocerca volvulus 0.0031 0.0206 0.0751
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0206 0.0231
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0013 0.0027
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0437 0.1002
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0025 0.0126 0.0261
Schistosoma mansoni cript-related 0.0016 0.0013 0.0027
Loa Loa (eye worm) RNA binding protein 0.0063 0.0614 0.1273
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.2391 0.496
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0186 0.0427
Loa Loa (eye worm) hypothetical protein 0.0047 0.0408 0.0846
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0206 0.0206
Echinococcus granulosus importin subunit beta 1 0.0029 0.0186 0.0208
Schistosoma mansoni importin beta-1 0.0029 0.0186 0.0386
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.3524 1
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0206 0.0428
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0206 0.0206
Schistosoma mansoni metabotropic glutamate receptor 0.0044 0.037 0.0766
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0891
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0016 0.0013 0.003
Schistosoma mansoni biogenic amine receptor 0.0031 0.0206 0.0428
Echinococcus granulosus leucine aminopeptidase protein 0.0106 0.1143 0.128
Brugia malayi G protein-coupled receptor 0.0031 0.0206 0.0748
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0089 0.0253
Loa Loa (eye worm) hypothetical protein 0.0065 0.0628 0.1303
Brugia malayi neuropeptide F receptor 0.0031 0.0206 0.0748
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0117 0.0331
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0206 0.0206
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0263 0.0546
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0186 0.0186
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0206 0.0206
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0614 0.1273
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1572 0.4461
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.003
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0031 0.0206 0.0206
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0013 0.003
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0013 0.0037
Leishmania major mitochondrial DNA polymerase beta 0.0296 0.3524 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0031 0.0206 0.0428
Entamoeba histolytica Ran family GTPase 0.0022 0.0089 0.1138
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0025 0.0126 0.0289
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0106 0.1143 0.2402
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0339 0.0963
Mycobacterium tuberculosis Probable oxidoreductase 0.0025 0.0126 0.0289
Echinococcus multilocularis allatostatin A receptor 0.0031 0.0206 0.0206
Schistosoma mansoni hypothetical protein 0.0102 0.1092 0.2265
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0016 0.0013 0.0037
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0025 0.0126 0.0358
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.043 0.0891
Entamoeba histolytica hypothetical protein 0.0035 0.0263 0.3362
Onchocerca volvulus 0.0016 0.0013 0.0048
Echinococcus granulosus GPCR family 2 0.0047 0.0408 0.0456
Onchocerca volvulus 0.0031 0.0206 0.0751
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0127 0.1411 0.4004
Onchocerca volvulus 0.0049 0.043 0.1565
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0013 0.0037
Echinococcus granulosus synaptojanin 1 0.0016 0.0013 0.0015
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0031 0.0206 0.0206
Brugia malayi hypothetical protein 0.0031 0.0206 0.0748
Echinococcus granulosus biogenic amine 5HT receptor 0.0399 0.4822 0.5397
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0031 0.0206 0.0428
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0783 0.2221
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0031 0.0206 0.0428
Brugia malayi hypothetical protein 0.0031 0.0206 0.0748
Echinococcus multilocularis G protein coupled receptor 139 0.0031 0.0206 0.0206
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0174 0.0195
Brugia malayi hypothetical protein 0.0031 0.0206 0.0748
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0016 0.0013 0.0013
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0049 0.0437 0.0906
Schistosoma mansoni ap endonuclease 0.0077 0.0783 0.1623
Trichomonas vaginalis hypothetical protein 0.0362 0.4361 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0186 0.0528
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0031 0.0206 0.0751
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Brugia malayi MH2 domain containing protein 0.0121 0.1335 0.4835
Chlamydia trachomatis cytosol aminopeptidase 0.0106 0.1143 0.2402
Brugia malayi Dopamine receptor 0.0031 0.0206 0.0748
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0025 0.0126 0.0289
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0016 0.0013 0.0027
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.1092 0.3956
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0437 0.124
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0255 0.0585
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0021 0.0082 0.0171
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0025 0.0126 0.0457
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0031 0.0206 0.0748
Echinococcus granulosus tachykinin peptides receptor 99D 0.0031 0.0206 0.0231
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0783 0.0783
Echinococcus multilocularis neuropeptide receptor A26 0.0031 0.0206 0.0206
Brugia malayi Flap endonuclease-1 0.0026 0.0149 0.054
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0206 0.0231
Schistosoma mansoni hypothetical protein 0.0031 0.0206 0.0428
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0206 0.0231
Echinococcus granulosus leucyl aminopeptidase 0.0021 0.0082 0.0092
Schistosoma mansoni ap endonuclease 0.0077 0.0783 0.1623
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0016 0.0013 0.0167
Echinococcus multilocularis g-protein coupled receptor 0.0031 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0102 0.1092 0.2265
Brugia malayi larval opioid receptor 0.0031 0.0206 0.0748
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.1681 0.3487
Brugia malayi hypothetical protein 0.012 0.1324 0.4796
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0783 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0031 0.0206 0.0206
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0031 0.0206 0.0748
Schistosoma mansoni ran 0.0022 0.0089 0.0185
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0031 0.0206 0.0206
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0021 0.0082 0.0234
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.006 0.0567 0.1175
Leishmania major pantothenate kinase subunit, putative 0.0018 0.0038 0.0109
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0031 0.0206 0.0428
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Schistosoma mansoni neuropeptide receptor 0.0031 0.0206 0.0428
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.0167
Echinococcus multilocularis deoxyribonuclease 1 2 0.0016 0.0013 0.0013
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0437 0.5582
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0206 0.0428
Brugia malayi hypothetical protein 0.0035 0.0263 0.0953
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0025 0.0126 0.0289
Echinococcus multilocularis tumor protein p63 0.0333 0.3996 0.3996
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0362 0.4361 1
Brugia malayi hypothetical protein 0.0031 0.0206 0.0748
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0783 0.1795
Echinococcus granulosus leucyl aminopeptidase 0.0021 0.0082 0.0092
Schistosoma mansoni histamine h1 receptor 0.0031 0.0206 0.0428
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0025 0.0126 0.0457
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0013 0.003
Echinococcus multilocularis leucine aminopeptidase protein 0.0106 0.1143 0.1143
Onchocerca volvulus 0.0048 0.0418 0.1523
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0021 0.0082 0.0299
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0206 0.0231
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.177 0.4059
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0025 0.0126 0.0358
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0206 0.0428
Plasmodium falciparum enoyl-acyl carrier reductase 0.0362 0.4361 1
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0013 0.0037
Schistosoma mansoni hypothetical protein 0.0047 0.0408 0.0846
Leishmania major endonuclease/exonuclease protein-like protein 0.0016 0.0013 0.0037
Echinococcus multilocularis dro:myosuppressin receptor 0.0031 0.0206 0.0206
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0016 0.0013 0.0167
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0206 0.0428
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.003
Brugia malayi RNA, U transporter 1 0.0083 0.0864 0.3132
Mycobacterium tuberculosis Probable exported protein 0.0016 0.0013 0.003
Echinococcus granulosus dro:myosuppressin receptor 0.0031 0.0206 0.0231
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0206 0.0428
Leishmania major hypothetical protein, conserved 0.0016 0.0013 0.0037
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0013 0.0037
Echinococcus granulosus neuropeptide receptor A26 0.0031 0.0206 0.0231
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0025 0.0126 0.0289
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0025 0.0126 0.0289
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0206 0.0206
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0013 0.0167
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0206 0.0206
Echinococcus multilocularis sex peptide receptor 0.0031 0.0206 0.0206
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0025 0.0126 0.0289
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0149 0.1905
Trypanosoma brucei aminopeptidase, putative 0.0021 0.0082 0.0234
Plasmodium vivax SET domain protein, putative 0.0029 0.0187 0.043
Echinococcus granulosus metabotropic glutamate receptor 2 0.0044 0.037 0.0414
Echinococcus granulosus geminin 0.0166 0.19 0.2127
Echinococcus granulosus neuropeptide FF receptor 2 0.0031 0.0206 0.0231
Leishmania major GTP-binding protein, putative 0.0022 0.0089 0.0253
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Schistosoma mansoni hypothetical protein 0.0166 0.19 0.3941
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0149 0.1767
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Brugia malayi Melatonin receptor type 1A 0.0031 0.0206 0.0748
Brugia malayi TAR-binding protein 0.0063 0.0614 0.2224
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0016 0.0013 0.003
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0025 0.0126 0.0289
Schistosoma mansoni alpha-1 adrenergic receptor 0.0031 0.0206 0.0428
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0206 0.0206
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.0167
Loa Loa (eye worm) hypothetical protein 0.0029 0.0187 0.0389
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Onchocerca volvulus 0.0031 0.0206 0.0751
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0106 0.1143 0.3245
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0783 0.1795
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0206 0.0206
Loa Loa (eye worm) oxidoreductase 0.0025 0.0126 0.0261
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0206 0.0428
Brugia malayi Dopamine receptor protein 2 0.0031 0.0206 0.0748
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.1335 0.2768
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0126 0.0289
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Entamoeba histolytica hypothetical protein 0.0024 0.0117 0.149
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0013 0.003
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0025 0.0126 0.0289
Echinococcus granulosus tar DNA binding protein 0.0063 0.0614 0.0687
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0437 0.1002
Entamoeba histolytica hypothetical protein 0.0035 0.0263 0.3362
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0013 0.0015
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0025 0.0126 0.0289
Schistosoma mansoni opsin-like receptor 0.0031 0.0206 0.0428
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0013 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0206 0.0428
Echinococcus granulosus neuropeptide receptor 0.0031 0.0206 0.0231
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0089 0.0185
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0025 0.0126 0.0289
Schistosoma mansoni amine GPCR 0.0031 0.0206 0.0428
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0025 0.0126 0.0289
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0031 0.0206 0.0428
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0016 0.0013 0.0037
Plasmodium falciparum M17 leucyl aminopeptidase 0.0106 0.1143 0.2622
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Echinococcus granulosus 7tm_1 domain containing protein 0.0031 0.0206 0.0231
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Schistosoma mansoni hypothetical protein 0.0313 0.3745 0.7768
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0013 0.0047
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0013 0.003
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0614 0.1273
Entamoeba histolytica hypothetical protein 0.0035 0.0263 0.3362
Echinococcus multilocularis conserved hypothetical protein 0.0696 0.8546 0.8546
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0783 0.2836
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0263 0.0295
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0187 0.021
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0025 0.0126 0.0289
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0021 0.0082 0.0234
Schistosoma mansoni hypothetical protein 0.0031 0.0206 0.0428
Brugia malayi hypothetical protein 0.0031 0.0206 0.0748
Schistosoma mansoni adenoreceptor 0.0031 0.0206 0.0428
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0126 0.0289
Schistosoma mansoni neuropeptide receptor 0.0031 0.0206 0.0428
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0013 0.003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0206 0.0231
Brugia malayi putative neuropeptide receptor NPR1 0.0031 0.0206 0.0748
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0362 0.4361 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Schistosoma mansoni hypothetical protein 0.0016 0.0013 0.0027
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0106 0.1143 0.2622
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.1572 0.4461
Brugia malayi neuropeptide F receptor 0.0031 0.0206 0.0748
Loa Loa (eye worm) hypothetical protein 0.012 0.1324 0.2745
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0117 0.0268
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0016 0.0013 0.003
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0013 0.0047
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0614 0.0614
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0783 0.1795
Echinococcus multilocularis orexin receptor type 2 0.0031 0.0206 0.0206
Echinococcus granulosus neutral sphingomyelinase 0.0016 0.0013 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0206 0.0231
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0428
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0025 0.0126 0.0358
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0783 0.1795
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0614 0.1273
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0021 0.0082 0.0299
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0206 0.0231
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0089 0.0253
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0408 0.0846
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0027
Echinococcus multilocularis mitogen activated protein kinase 11 0.0127 0.1411 0.1411
Onchocerca volvulus 0.0031 0.0206 0.0751
Mycobacterium ulcerans oxidoreductase 0.0025 0.0126 0.0289
Toxoplasma gondii leucyl aminopeptidase LAP 0.0106 0.1143 0.2622
Brugia malayi hypothetical protein 0.0031 0.0206 0.0748
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0126 0.0289
Brugia malayi Metabotropic glutamate receptor precursor. 0.0052 0.0476 0.1726
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0031 0.0206 0.0428
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0362 0.4361 1
Mycobacterium tuberculosis Possible oxidoreductase 0.0025 0.0126 0.0289
Onchocerca volvulus Huntingtin homolog 0.012 0.1324 0.4819
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0031 0.0206 0.0428
Leishmania major oxidoreductase-like protein 0.0025 0.0126 0.0358
Schistosoma mansoni neuropeptide receptor 0.0031 0.0206 0.0428
Onchocerca volvulus 0.0031 0.0206 0.0751
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0013 0.0037
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0016 0.0013 0.003
Schistosoma mansoni amine GPCR 0.0031 0.0206 0.0428
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0013 0.0013
Onchocerca volvulus 0.0031 0.0206 0.0751
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0281 0.0643
Onchocerca volvulus 0.0016 0.0013 0.0048
Brugia malayi hypothetical protein 0.0031 0.0206 0.0748
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0255 0.0585

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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