Detailed information for compound 568663

Basic information

Technical information
  • TDR Targets ID: 568663
  • Name: 2-hydroxybenzoic acid; sodium
  • MW: 161.111 | Formula: C7H6NaO3
  • H donors: 2 H acceptors: 3 LogP: 1.64 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)c1ccccc1O.[Na]
  • InChi: 1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);
  • InChiKey: REWPEPFZCALMJB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • salicylic acid; sodium
  • Sodium Salicylate
  • NSC202167
  • Salicylate, sodium
  • Sodium salicylate (NaO3C7H5)
  • Sodium salicylic acid
  • WLN: QVR BQ &-NA-
  • o-Hydroxybenzoic acid, sodium salt
  • o-Hydroxybenzoic sodium salt

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0052 0.0429 0.0429
Onchocerca volvulus 0.0042 0.0292 0.0376
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0089 0.0905 0.0905
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0042 0.0292 0.0376
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0042 0.0292 0.0268
Entamoeba histolytica hypothetical protein 0.004 0.0267 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0089 0.0905 0.0905
Echinococcus multilocularis thyroid hormone receptor alpha 0.0089 0.0905 0.0905
Brugia malayi photoreceptor-specific nuclear receptor 0.0089 0.0905 0.1214
Echinococcus granulosus FTZ F1 alpha 0.0089 0.0905 0.0905
Echinococcus multilocularis thioredoxin glutathione reductase 0.0043 0.0302 0.0302
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0349 0.4319 0.6543
Onchocerca volvulus 0.0089 0.0905 0.2412
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0106 0.1139 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0104 0.111 0.111
Schistosoma mansoni importin beta-1 0.0033 0.0173 0.0173
Echinococcus multilocularis nuclear receptor nhr 48 0.0042 0.0292 0.0292
Schistosoma mansoni tar DNA-binding protein 0.0275 0.3346 0.3346
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0089 0.0905 0.1359
Schistosoma mansoni thyroid hormone receptor 0.0089 0.0905 0.0905
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0178 0.0178
Brugia malayi Pre-SET motif family protein 0.0231 0.2771 0.4095
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0089 0.0905 0.1214
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0042 0.0292 0.0376
Schistosoma mansoni coup transcription factor 0.0089 0.0905 0.0905
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0089 0.0905 0.0905
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0104 0.111 0.111
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0178 0.0178
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0178 0.0118
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Loa Loa (eye worm) hypothetical protein 0.0047 0.0357 0.0528
Loa Loa (eye worm) hypothetical protein 0.0165 0.1907 0.2881
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.0647 0.0647
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0047 0.0357 0.0357
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0042 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0047 0.0357 0.0528
Brugia malayi Nuclear hormone receptor E75 0.0042 0.0292 0.0268
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0292 0.0292
Schistosoma mansoni hypothetical protein 0.0353 0.437 0.437
Brugia malayi RNA binding protein 0.0275 0.3346 0.4982
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0089 0.0905 0.0905
Schistosoma mansoni zinc finger protein 0.0042 0.0292 0.0292
Brugia malayi hypothetical protein 0.0047 0.0357 0.0369
Brugia malayi nuclear receptor NHR-67 0.0042 0.0292 0.0268
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0042 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0047 0.0355 0.0525
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0052 0.0429 0.0429
Brugia malayi glutathione reductase 0.0042 0.0294 0.0272
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Brugia malayi MH2 domain containing protein 0.0252 0.3042 0.4513
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0089 0.0905 0.0905
Echinococcus multilocularis FTZ F1 alpha 0.0089 0.0905 0.0905
Trypanosoma brucei trypanothione reductase 0.0042 0.0294 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0082 0.0082
Echinococcus granulosus Nuclear hormone receptor HR96 0.0042 0.0292 0.0292
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0068 0.064 0.064
Echinococcus granulosus zinc finger protein 0.0022 0.0038 0.0038
Echinococcus multilocularis zinc finger protein 0.0022 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0089 0.0905 0.1359
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0089 0.0905 0.0905
Schistosoma mansoni microtubule-associated protein tau 0.0783 1 1
Loa Loa (eye worm) hypothetical protein 0.0171 0.199 0.3007
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.0647 0.0647
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0089 0.0905 0.0905
Echinococcus granulosus neuropeptide receptor 0.0179 0.2094 0.2094
Brugia malayi nuclear receptor NHR-88 0.0042 0.0292 0.0268
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0089 0.0905 0.1214
Echinococcus multilocularis snurportin 1 0.0349 0.4319 0.4319
Schistosoma mansoni hypothetical protein 0.0052 0.0429 0.0429
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0047 0.0357 0.0357
Brugia malayi ecdysteroid receptor 0.0089 0.0905 0.1214
Brugia malayi Bromodomain containing protein 0.0044 0.0319 0.031
Loa Loa (eye worm) glutathione reductase 0.0042 0.0294 0.0433
Brugia malayi nuclear receptor RXR 0.0042 0.0292 0.0268
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0104 0.111 0.111
Loa Loa (eye worm) hypothetical protein 0.0089 0.0905 0.1359
Plasmodium vivax thioredoxin reductase, putative 0.0042 0.0294 1
Onchocerca volvulus 0.0107 0.1142 0.32
Echinococcus granulosus thyroid hormone receptor alpha 0.0042 0.0292 0.0292
Loa Loa (eye worm) latrophilin receptor protein 2 0.0052 0.0429 0.0637
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0042 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0049 0.0384 0.0569
Onchocerca volvulus 0.0042 0.0292 0.0376
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0068 0.064 0.064
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0089 0.0905 0.0905
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0047 0.0357 0.0357
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0248
Trypanosoma cruzi trypanothione reductase, putative 0.0042 0.0294 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0096 0.0999 0.8342
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0089 0.0905 0.0905
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0089 0.0905 0.1214
Brugia malayi Importin beta-1 subunit 0.0033 0.0173 0.0085
Echinococcus multilocularis tar DNA binding protein 0.0275 0.3346 0.3346
Brugia malayi Nuclear hormone receptor-like 1 0.0089 0.0905 0.1214
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0089 0.0905 0.0905
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0089 0.0905 0.0905
Echinococcus multilocularis geminin 0.0353 0.437 0.437
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0096 0.0999 0.8342
Schistosoma mansoni hypothetical protein 0.004 0.0267 0.0267
Brugia malayi TAR-binding protein 0.0275 0.3346 0.4982
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0275 0.3346 0.5065
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0434 0.0434
Brugia malayi hypothetical protein 0.004 0.0267 0.0231
Schistosoma mansoni tar DNA-binding protein 0.0275 0.3346 0.3346
Brugia malayi Steroid receptor seven-up type 2 0.0089 0.0905 0.1214
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0104 0.111 0.111
Schistosoma mansoni hypothetical protein 0.0107 0.1142 0.1142
Schistosoma mansoni tar DNA-binding protein 0.0275 0.3346 0.3346
Loa Loa (eye worm) hypothetical protein 0.0113 0.1223 0.1842
Brugia malayi hypothetical protein 0.0171 0.199 0.289
Schistosoma mansoni survival motor neuron protein 0.0107 0.1142 0.1142
Echinococcus granulosus Nuclear hormone receptor HR96 0.0042 0.0292 0.0292
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0052 0.0429 0.0429
Loa Loa (eye worm) hypothetical protein 0.0089 0.0905 0.1359
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0104 0.111 0.111
Loa Loa (eye worm) nuclear receptor NHR-67 0.0042 0.0292 0.0429
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.0283 0.0283
Brugia malayi Pre-SET motif family protein 0.0033 0.0178 0.0093
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0047 0.0357 0.0528
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0042 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0434 0.0434
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0089 0.0905 0.1214
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0054 0.0068
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0089 0.0905 0.1214
Mycobacterium tuberculosis Probable reductase 0.0096 0.0999 0.8342
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0104 0.111 0.1671
Loa Loa (eye worm) thioredoxin reductase 0.0042 0.0294 0.0433
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0089 0.0905 0.0905
Loa Loa (eye worm) hypothetical protein 0.0089 0.0905 0.1359
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Loa Loa (eye worm) transcription factor SMAD2 0.0252 0.3042 0.4604
Schistosoma mansoni hypothetical protein 0.0052 0.0429 0.0429
Loa Loa (eye worm) hypothetical protein 0.0047 0.0357 0.0528
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0357 0.0369
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0104 0.111 0.1532
Loa Loa (eye worm) hypothetical protein 0.0089 0.0905 0.1359
Echinococcus multilocularis GPCR, family 2 0.0052 0.0429 0.0429
Entamoeba histolytica hypothetical protein 0.004 0.0267 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0165 0.1907 0.2762
Schistosoma mansoni hypothetical protein 0.0052 0.0429 0.0429
Loa Loa (eye worm) hypothetical protein 0.0047 0.0357 0.0528
Loa Loa (eye worm) TAR-binding protein 0.0275 0.3346 0.5065
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0096 0.0999 0.8342
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0052 0.0429 0.0429
Echinococcus granulosus survival motor neuron protein 1 0.0523 0.6596 0.6596
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0647 0.0647
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0082 0.0082
Schistosoma mansoni thyroid hormone receptor 0.0089 0.0905 0.0905
Trichomonas vaginalis set domain proteins, putative 0.0263 0.3189 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0096 0.0999 0.8342
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0165 0.1907 0.2881
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0052 0.0429 0.048
Echinococcus multilocularis ecdysone induced protein 78C 0.0089 0.0905 0.0905
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0647 0.5
Loa Loa (eye worm) hypothetical protein 0.0044 0.032 0.0471
Onchocerca volvulus Protein ultraspiracle homolog 0.0089 0.0905 0.2412
Echinococcus granulosus nuclear receptor nhr 48 0.0042 0.0292 0.0292
Echinococcus multilocularis neuropeptide receptor 0.0179 0.2094 0.2094
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0104 0.111 0.111
Loa Loa (eye worm) hypothetical protein 0.0089 0.0905 0.1359
Mycobacterium tuberculosis Probable oxidoreductase 0.0106 0.1139 1
Brugia malayi ecdysone receptor 0.0042 0.0292 0.0268
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Loa Loa (eye worm) hypothetical protein 0.0089 0.0905 0.1359
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0096 0.0999 0.8342
Brugia malayi hypothetical protein 0.0042 0.0292 0.0268
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0089 0.0905 0.1359
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0089 0.0905 0.1359
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0089 0.0905 0.1214
Schistosoma mansoni hypothetical protein 0.0052 0.0429 0.0429
Loa Loa (eye worm) hypothetical protein 0.0089 0.0905 0.1359
Onchocerca volvulus 0.0171 0.199 0.6018
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0089 0.0905 0.0905
Brugia malayi nuclear hormone receptor 0.0042 0.0292 0.0268
Schistosoma mansoni hypothetical protein 0.0024 0.0054 0.0054
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0178 0.0178
Schistosoma mansoni hypothetical protein 0.0353 0.437 0.437
Plasmodium vivax glutathione reductase, putative 0.0042 0.0294 1
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.0647 1
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0292 0.0292
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0089 0.0905 0.1214
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0089 0.0905 0.1214
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0647 0.0647
Plasmodium falciparum thioredoxin reductase 0.0042 0.0294 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0089 0.0905 0.1214
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Brugia malayi hypothetical protein 0.0047 0.0357 0.0369
Toxoplasma gondii thioredoxin reductase 0.0042 0.0294 0.2565
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0047 0.0357 0.0357
Plasmodium vivax SET domain protein, putative 0.0033 0.0178 0.0458
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0267 0.0267
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0647 0.5
Echinococcus granulosus ecdysone induced protein 78C 0.0089 0.0905 0.0905
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0089 0.0905 0.1214
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0173 0.0173
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0089 0.0905 0.0905
Brugia malayi Bromodomain containing protein 0.0086 0.0869 0.1159
Brugia malayi hypothetical protein 0.0042 0.0292 0.0268
Brugia malayi latrophilin 2 splice variant baaae 0.0113 0.1223 0.1705
Brugia malayi nuclear receptor RXR 0.0047 0.0357 0.0369
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0042 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0052 0.0429 0.0637
Plasmodium falciparum glutathione reductase 0.0042 0.0294 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0089 0.0905 0.1359
Schistosoma mansoni nuclear receptor 0.0042 0.0292 0.0292
Onchocerca volvulus 0.0263 0.3189 1
Schistosoma mansoni hypothetical protein 0.0349 0.4319 0.4319
Brugia malayi conserved hypotetical protein 0.0042 0.0292 0.0268
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0267 0.0267
Schistosoma mansoni retinoic acid receptor RXR 0.0089 0.0905 0.0905
Onchocerca volvulus Bile acid receptor homolog 0.0089 0.0905 0.2412
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0089 0.0905 0.0905
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0089 0.0905 0.1214
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0162 0.0162
Brugia malayi nuclear hormone receptor family member nhr-6 0.0042 0.0292 0.0268
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0089 0.0905 0.2412
Loa Loa (eye worm) nuclear hormone receptor 0.0042 0.0292 0.0429
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0267 0.0267
Schistosoma mansoni RAR-like nuclear receptor 0.0089 0.0905 0.0905
Brugia malayi Thioredoxin reductase 0.0042 0.0294 0.0272
Leishmania major trypanothione reductase 0.0042 0.0294 0.3651
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0082 0.0082
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.2771 0.4192
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.0283 0.0283
Echinococcus multilocularis microtubule associated protein 2 0.0783 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0089 0.0905 0.1214
Loa Loa (eye worm) hypothetical protein 0.0081 0.0805 0.1208
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0357 0.0369
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0106 0.1139 1
Loa Loa (eye worm) steroid hormone receptor 0.0089 0.0905 0.1359
Echinococcus multilocularis survival motor neuron protein 1 0.0523 0.6596 0.6596
Echinococcus multilocularis G protein coupled receptor 139 0.0179 0.2094 0.2094
Schistosoma mansoni tar DNA-binding protein 0.0275 0.3346 0.3346
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0107 0.1142 0.1581
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0089 0.0905 0.0905
Schistosoma mansoni bromodomain containing protein 0.0072 0.0693 0.0693
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0089 0.0905 0.0905
Echinococcus granulosus GPCR family 2 0.0052 0.0429 0.0429
Brugia malayi RNA recognition motif domain containing protein 0.0275 0.3346 0.4982
Brugia malayi nuclear hormone receptor 0.0089 0.0905 0.1214
Loa Loa (eye worm) hypothetical protein 0.0047 0.0357 0.0528
Brugia malayi nuclear receptor NHR-88 0.0089 0.0905 0.1214
Brugia malayi RNA, U transporter 1 0.0093 0.0963 0.1304
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.0647 0.4171
Loa Loa (eye worm) DR-78 0.0042 0.0292 0.0429
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0042 0.0292 0.0429
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0434 0.0434
Brugia malayi orphan nuclear receptor NR2E1 0.0042 0.0292 0.0268
Schistosoma mansoni nuclear receptor 0.0042 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0053 0.0434 0.0645
Loa Loa (eye worm) hypothetical protein 0.0523 0.6596 1
Echinococcus granulosus tar DNA binding protein 0.0275 0.3346 0.3346
Echinococcus granulosus thioredoxin glutathione reductase 0.0043 0.0302 0.0302
Brugia malayi steroid hormone receptor 0.0089 0.0905 0.1214
Echinococcus granulosus snurportin 1 0.0349 0.4319 0.4319
Brugia malayi Nuclear hormone receptor E75 0.0042 0.0292 0.0268
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0089 0.0905 0.0905
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0089 0.0905 0.0905
Echinococcus granulosus importin subunit beta 1 0.0033 0.0173 0.0173
Schistosoma mansoni nuclear receptor nhr-48 0.0042 0.0292 0.0292
Schistosoma mansoni zinc finger protein 0.0022 0.0038 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0089 0.0905 0.1359
Schistosoma mansoni nuclear hormone receptor 0.0089 0.0905 0.0905
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0165 0.1907 0.2762
Entamoeba histolytica hypothetical protein 0.004 0.0267 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0042 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Brugia malayi tailless protein 0.0042 0.0292 0.0268
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0647 0.5
Brugia malayi Latrophilin receptor protein 2 0.0052 0.0429 0.048
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0089 0.0905 0.1214
Loa Loa (eye worm) RNA binding protein 0.0275 0.3346 0.5065
Echinococcus granulosus geminin 0.0353 0.437 0.437
Schistosoma mansoni tar DNA-binding protein 0.0275 0.3346 0.3346
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0106 0.1139 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0089 0.0905 0.1359
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Schistosoma mansoni neuropeptide receptor 0.0179 0.2094 0.2094
Brugia malayi nuclear hormone receptor family member odr-7 0.0042 0.0292 0.0268
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.0647 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0104 0.111 0.111
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.0429
Brugia malayi hypothetical protein 0.0523 0.6596 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0252 0.3042 0.4604
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0042 0.0292 0.0292
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0089 0.0905 0.1359
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0434 0.0434
Entamoeba histolytica hypothetical protein 0.004 0.0267 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0292 0.0292
Schistosoma mansoni hypothetical protein 0.0113 0.1223 0.1223
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0089 0.0905 0.0905

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

17 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.