Detailed information for compound 570098

Basic information

Technical information
  • TDR Targets ID: 570098
  • Name: 2-aminoacetic acid hydrochloride
  • MW: 111.528 | Formula: C2H6ClNO2
  • H donors: 2 H acceptors: 2 LogP: -2.6 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCC(=O)O.Cl
  • InChi: 1S/C2H5NO2.ClH/c3-1-2(4)5;/h1,3H2,(H,4,5);1H
  • InChiKey: IVLXQGJVBGMLRR-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-azanylethanoic acid hydrochloride
  • Glycine
  • carboxymethylazanium chloride
  • carboxymethylammonium chloride
  • 2-aminoacetic acid; hydron; chloride
  • 2-aminoethanoic acid; hydron; chloride
  • 2-aminoethanoic acid hydrochloride
  • 6000-43-7
  • Aminoacetic acid hydrochloride
  • CCRIS 3355
  • EINECS 227-841-8
  • GLYCINE, HYDROCHLORIDE
  • Glycocoll hydrochloride
  • Amino acetic acid hydrochloride
  • 55097_FLUKA
  • Glycine hydrochloride solution
  • G2879_SIGMA
  • Glycine hydrochloride

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.4327 0.3471
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 1 0.5
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 1 1
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.1957 0.1957
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Entamoeba histolytica recQ family helicase, putative 0.0011 0.2097 0.2097
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.1957 0.1957
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0037 1 1
Brugia malayi casein kinase II, putaitve 0.0011 0.1957 0.0744
Echinococcus multilocularis bloom syndrome protein 0.0021 0.5113 0.4376
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Schistosoma mansoni DNA helicase recq1 0.0009 0.1311 0.1311
Giardia lamblia Casein kinase II beta chain 0.0011 0.1957 0.0744
Loa Loa (eye worm) hypothetical protein 0.0017 0.3802 0.2868
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 1 1
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 1 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Schistosoma mansoni casein kinase II beta subunit 0.0037 1 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.1311 0.1311
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.1311 0.1311
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.2964 0.2964
Plasmodium vivax casein kinase II beta chain, putative 0.0037 1 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.375 0.375
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0037 1 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Echinococcus granulosus casein kinase ii subunit beta 0.0037 1 1
Loa Loa (eye worm) RecQ helicase 0.0021 0.5113 0.4376
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.2097 0.0174
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.5113 0.3924
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Loa Loa (eye worm) casein kinase II 0.0011 0.1957 0.0744
Schistosoma mansoni DNA helicase recq5 0.0009 0.1311 0.1311
Giardia lamblia Casein kinase II beta chain 0.0037 1 1
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.5113 0.3924
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 1 0.5
Plasmodium falciparum casein kinase II beta chain 0.0037 1 1
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 1 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Plasmodium vivax casein kinase II beta chain, putative 0.0037 1 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0037 1 1
Loa Loa (eye worm) Csnk2b protein 0.0037 1 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.5113 0.4376
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Plasmodium falciparum casein kinase II beta chain 0.0037 1 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 1 1
Echinococcus multilocularis casein kinase ii subunit beta 0.0037 1 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 1 1
Echinococcus granulosus bloom syndrome protein 0.0021 0.5113 0.4376
Toxoplasma gondii ck2 beta subunit 0.0037 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

165 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.