Detailed information for compound 570854

Basic information

Technical information
  • TDR Targets ID: 570854
  • Name: (4-nitrophenoxy)-phenyl-phosphinic acid
  • MW: 279.185 | Formula: C12H10NO5P
  • H donors: 1 H acceptors: 4 LogP: 2.14 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OP(=O)(c1ccccc1)Oc1ccc(cc1)[N+](=O)[O-]
  • InChi: 1S/C12H10NO5P/c14-13(15)10-6-8-11(9-7-10)18-19(16,17)12-4-2-1-3-5-12/h1-9H,(H,16,17)
  • InChiKey: NRGZTHQFAQCJCQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (4-nitrophenoxy)-phenylphosphinic acid
  • O-4-nitrophenyl phenylphosphonate
  • 4-nitrophenyl phenylphosphonate
  • Phenylphosphonic acid, mono(4-nitrophenyl) ester
  • N2881_SIGMA
  • Pnppph

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0657 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.1537 0.1498
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.009 0.0044
Mycobacterium leprae Probable lipase LipE 0.004 0.0504 0.7014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0367 0.0647
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0115 0.2066 0.2029
Trichomonas vaginalis esterase, putative 0.004 0.0504 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0657 0.0849
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0504 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.009 0.0044
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.009 0.0044
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0657 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0204 0.3921 0.5384
Loa Loa (eye worm) hypothetical protein 0.0249 0.4848 0.667
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.009 0.0044
Loa Loa (eye worm) hypothetical protein 0.002 0.009 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.009 0.0061
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.009 0.0044
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0657 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0657 1
Leishmania major hypothetical protein, conserved 0.0025 0.0182 0.2213
Loa Loa (eye worm) hypothetical protein 0.002 0.009 0.0061
Brugia malayi RNA recognition motif domain containing protein 0.0204 0.3921 0.5413
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0407 0.5129
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0504 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0504 0.0636
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0504 0.046
Loa Loa (eye worm) hypothetical protein 0.0047 0.0657 0.0849
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0504 0.5
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0115 0.2066 0.2029
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.009 0.0125
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0657 1
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0504 0.0924
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0182 0.2954
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0657 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0407 0.0502
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.009 0.0125
Schistosoma mansoni thyroid hormone receptor 0.002 0.009 0.0044
Brugia malayi steroid hormone receptor 0.002 0.009 0.0125
Loa Loa (eye worm) hypothetical protein 0.004 0.0504 0.0636
Echinococcus multilocularis GPCR, family 2 0.0115 0.2066 0.2029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0367 0.0647
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.009 0.0125
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0504 0.7014
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0145 0.2145
Loa Loa (eye worm) hypothetical protein 0.002 0.009 0.0061
Brugia malayi Steroid receptor seven-up type 2 0.002 0.009 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.009 0.0061
Loa Loa (eye worm) hypothetical protein 0.0364 0.7244 1
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0145 0.2145
Plasmodium vivax hypothetical protein, conserved 0.004 0.0504 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.009 0.0125
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.1537 0.1498
Leishmania major hypothetical protein, conserved 0.004 0.0504 0.7494
Brugia malayi nuclear receptor NHR-88 0.002 0.009 0.0125
Echinococcus granulosus tar DNA binding protein 0.0204 0.3921 0.3893
Brugia malayi nuclear hormone receptor 0.002 0.009 0.0125
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.1359 0.1876
Schistosoma mansoni ap endonuclease 0.004 0.0504 0.046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0182 0.0188
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0657 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0504 0.046
Brugia malayi beta-lactamase family protein 0.004 0.0504 0.0696
Loa Loa (eye worm) hypothetical protein 0.002 0.009 0.0061
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.009 0.0044
Schistosoma mansoni hypothetical protein 0.0249 0.4848 0.4824
Schistosoma mansoni tar DNA-binding protein 0.0204 0.3921 0.3893
Schistosoma mansoni hypothetical protein 0.0115 0.2066 0.2029
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0504 0.046
Schistosoma mansoni tar DNA-binding protein 0.0204 0.3921 0.3893
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0504 0.7011
Mycobacterium ulcerans hypothetical protein 0.0047 0.0657 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.009 0.0061
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0504 0.046
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0504 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.009 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.009 0.0061
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0145 0.2145
Schistosoma mansoni hypothetical protein 0.0496 1 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0504 0.9997
Loa Loa (eye worm) steroid hormone receptor 0.002 0.009 0.0061
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0504 0.0636
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.009 0.0044
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0504 0.7014
Schistosoma mansoni hypothetical protein 0.0496 1 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0504 0.9997
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0657 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0504 0.0924
Mycobacterium leprae conserved hypothetical protein 0.004 0.0504 0.7014
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.009 0.0125
Schistosoma mansoni tar DNA-binding protein 0.0204 0.3921 0.3893
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0145 0.2145
Onchocerca volvulus 0.004 0.0504 0.3261
Brugia malayi beta-lactamase family protein 0.004 0.0504 0.0696
Loa Loa (eye worm) hypothetical protein 0.0047 0.0657 0.0849
Echinococcus multilocularis geminin 0.0496 1 1
Mycobacterium ulcerans lipase LipD 0.004 0.0504 0.7014
Loa Loa (eye worm) hypothetical protein 0.002 0.009 0.0061
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0504 0.0924
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.009 0.0125
Brugia malayi hypothetical protein 0.0025 0.0182 0.0251
Loa Loa (eye worm) beta-lactamase 0.004 0.0504 0.0636
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.009 0.0125
Loa Loa (eye worm) hypothetical protein 0.004 0.0504 0.0636
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.009 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.009 0.0125
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0504 1
Schistosoma mansoni tar DNA-binding protein 0.0204 0.3921 0.3893
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.009 0.0044
Mycobacterium tuberculosis Conserved protein 0.004 0.0504 0.0924
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.009 0.0044
Schistosoma mansoni thyroid hormone receptor 0.002 0.009 0.0044
Loa Loa (eye worm) hypothetical protein 0.002 0.009 0.0061
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0657 0.0907
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0182 0.2954
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.009 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.009 0.0061
Loa Loa (eye worm) hypothetical protein 0.0035 0.0407 0.0502
Loa Loa (eye worm) latrophilin receptor protein 2 0.0115 0.2066 0.2806
Brugia malayi Latrophilin receptor protein 2 0.0115 0.2066 0.2852
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.009 0.0061
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.009 0.0044
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0504 1
Loa Loa (eye worm) RNA binding protein 0.0204 0.3921 0.5384
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.1537 0.1498
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0407 0.0729
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.009 0.0044
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0407 0.7891
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0657 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0657 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.009 0.0125
Loa Loa (eye worm) hypothetical protein 0.004 0.0504 0.0636
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0504 0.0696
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0182 0.2954
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0115 0.2066 0.2029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0407 0.0502
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.009 0.0125
Brugia malayi latrophilin 2 splice variant baaae 0.0249 0.4848 0.6692
Schistosoma mansoni nuclear hormone receptor 0.002 0.009 0.0044
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0182 0.2954
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0657 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.1537 0.1498
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.009 0.0125
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.1359 0.1319
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.009 0.0044
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0256 0.5003 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.009 0.0044
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0407 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.009 0.0125
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0407 0.7889
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.009 0.0044
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0364 0.7244 1
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0657 0.0907
Onchocerca volvulus 0.0047 0.0657 0.4468
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0367 0.0647
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0657 1
Loa Loa (eye worm) hypothetical protein 0.0115 0.2066 0.2806
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0145 0.2145
Schistosoma mansoni tar DNA-binding protein 0.0204 0.3921 0.3893
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0504 0.0923
Schistosoma mansoni hypothetical protein 0.0115 0.2066 0.2029
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0657 0.1233
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.009 0.0044
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0504 0.0924
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.009 0.0044
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.009 0.0044
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0504 1
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.1359 0.1319
Loa Loa (eye worm) hypothetical protein 0.0035 0.0407 0.0502
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0046 0.0064
Brugia malayi TAR-binding protein 0.0204 0.3921 0.5413
Mycobacterium tuberculosis Conserved protein 0.004 0.0504 0.0924
Toxoplasma gondii exonuclease III APE 0.004 0.0504 0.9997
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0504 0.7011
Schistosoma mansoni hypothetical protein 0.0115 0.2066 0.2029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0407 0.0502
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0504 0.0924
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0657 0.0907
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.1537 0.1498
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.009 0.0125
Onchocerca volvulus 0.0081 0.1359 1
Onchocerca volvulus 0.004 0.0504 0.3261
Toxoplasma gondii ABC1 family protein 0.004 0.0504 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0504 0.0696
Echinococcus multilocularis FTZ F1 alpha 0.002 0.009 0.0044
Loa Loa (eye worm) hypothetical protein 0.0081 0.1359 0.1823
Loa Loa (eye worm) hypothetical protein 0.004 0.0504 0.0636
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0657 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0504 0.0636
Echinococcus multilocularis tar DNA binding protein 0.0204 0.3921 0.3893
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.009 0.0044
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0504 0.7492
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0504 1
Mycobacterium tuberculosis Conserved protein 0.004 0.0504 0.0924
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0504 0.046
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0504 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.1537 0.1498
Mycobacterium ulcerans beta-lactamase 0.004 0.0504 0.7014
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.009 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.009 0.0044
Echinococcus granulosus FTZ F1 alpha 0.002 0.009 0.0044
Brugia malayi ecdysteroid receptor 0.002 0.009 0.0125
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.009 0.0125
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.1537 0.2071
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0504 0.9997
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0182 0.2954
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.1537 0.1498
Brugia malayi beta-lactamase 0.004 0.0504 0.0696
Schistosoma mansoni coup transcription factor 0.002 0.009 0.0044
Loa Loa (eye worm) hypothetical protein 0.002 0.009 0.0061
Loa Loa (eye worm) hypothetical protein 0.002 0.009 0.0061
Brugia malayi Calcitonin receptor-like protein seb-1 0.0364 0.7244 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0367 0.0647
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0504 0.9997
Brugia malayi isocitrate dehydrogenase 0.0018 0.0046 0.0064
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.1359 0.1319
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.1537 0.2122
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0504 1
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0504 0.0924
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0364 0.7244 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.009 0.0125
Schistosoma mansoni hypothetical protein 0.0115 0.2066 0.2029
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.009 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0504 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0657 0.1233
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0182 0.2954
Echinococcus granulosus GPCR family 2 0.0115 0.2066 0.2029
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0657 1
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0504 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0115 0.2066 0.2029
Onchocerca volvulus 0.004 0.0504 0.3261
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0145 0.0198
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0504 0.0924
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0145 0.1607
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0657 1
Mycobacterium ulcerans hypothetical protein 0.004 0.0504 0.7014
Loa Loa (eye worm) hypothetical protein 0.004 0.0504 0.0636
Loa Loa (eye worm) TAR-binding protein 0.0204 0.3921 0.5384
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.009 0.0061
Schistosoma mansoni ap endonuclease 0.004 0.0504 0.046
Brugia malayi RNA binding protein 0.0204 0.3921 0.5413
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0115 0.2066 0.2852
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0182 0.2954
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0504 0.046
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.009 0.0044

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.