Detailed information for compound 571304

Basic information

Technical information
  • TDR Targets ID: 571304
  • Name: (2R,3S,5R)-3-(dimethylamino)-2,5-dihydroxy-he xanal
  • MW: 175.225 | Formula: C8H17NO3
  • H donors: 2 H acceptors: 3 LogP: -0.68 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C[C@@H]([C@@H](N(C)C)C[C@H](O)C)O
  • InChi: 1S/C8H17NO3/c1-6(11)4-7(9(2)3)8(12)5-10/h5-8,11-12H,4H2,1-3H3/t6-,7+,8+/m1/s1
  • InChiKey: VTJCSBJRQLZNHE-CSMHCCOUSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R,3S,5R)-3-(dimethylamino)-2,5-dihydroxyhexanal
  • desosamine
  • (2R,3S,5R)-3-dimethylamino-2,5-dihydroxyhexanal
  • (2R,3S,5R)-3-dimethylamino-2,5-dihydroxy-hexanal
  • 5779-39-5
  • 3,4,6-trideoxy-3-dimethylamino-D-xylo-hexose
  • CHEBI:32540
  • D-xylo-Hexose, 3,4,6-trideoxy-3-(dimethylamino)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus dual specificity 0.0088 0.2125 0.2125
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.002 0.0424 0.0623
Brugia malayi AMP-binding enzyme family protein 0.002 0.0424 0.0571
Loa Loa (eye worm) hypothetical protein 0.001 0.0169 0.0222
Schistosoma mansoni hypothetical protein 0.0016 0.0301 0.0294
Brugia malayi Muscleblind-like protein 0.0293 0.7302 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.007 0.0141
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0169 0.0222
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0129 0.0167
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.1252 0.2536
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0156 0.0204
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0026 0.0019
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0012 0.0219 0.0151
Brugia malayi Fli-1 protein 0.0215 0.5333 0.7302
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0005 0.0026 0.0019
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0052 0.1218 0.2341
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0424 0.0623
Echinococcus granulosus ETS transcription factor Elf 5 0.001 0.0169 0.0169
Brugia malayi tailless protein 0.0005 0.0026 0.0025
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0012 0.0219 0.0151
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0755 0.1026
Entamoeba histolytica hypothetical protein 0.0088 0.2125 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0301 0.0403
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0012 0.0219 0.0151
Plasmodium falciparum enoyl-acyl carrier reductase 0.0181 0.4483 1
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.0154 0.0693
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0424 0.0479
Leishmania major 4-coumarate:coa ligase-like protein 0.0069 0.166 0.7562
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0156 0.0204
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0219 0.0291
Loa Loa (eye worm) hypothetical protein 0.002 0.0424 0.0571
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0069 0.166 0.3479
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0156 0.0156
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0219 0.0291
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Brugia malayi Ets-domain containing protein 0.001 0.0169 0.0222
Loa Loa (eye worm) hypothetical protein 0.0061 0.1437 0.196
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.007 0.0141
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0052 0.1218 0.1659
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0012 0.0219 0.0332
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0088 0.2125 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0156 0.0156
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0069 0.166 0.3479
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Entamoeba histolytica acyl-coA synthetase, putative 0.0069 0.166 0.7807
Echinococcus granulosus expressed protein 0.0004 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0012 0.0219 0.0151
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0156 0.0204
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0156 0.0204
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0156 0.0204
Schistosoma mansoni hypothetical protein 0.001 0.0169 0.0162
Onchocerca volvulus 0.0028 0.0618 0.1683
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0156 0.0156
Schistosoma mansoni gabp alpha 0.0071 0.1696 0.169
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Echinococcus multilocularis ewsr:fli fusion protein type 0.001 0.0169 0.0169
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0154 0.0147
Brugia malayi AMP-binding enzyme family protein 0.0069 0.166 0.2266
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.002 0.0424 0.0571
Mycobacterium ulcerans acyl-CoA synthetase 0.0069 0.166 0.3479
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0052 0.1218 0.2457
Loa Loa (eye worm) hypothetical protein 0.001 0.0154 0.0201
Brugia malayi hypothetical protein 0.0005 0.0026 0.0025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0005 0.0026 0.0026
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0086 0.0086
Leishmania major 4-coumarate:coa ligase-like protein 0.0069 0.166 0.7562
Loa Loa (eye worm) hypothetical protein 0.0293 0.7302 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.002 0.0424 0.0479
Entamoeba histolytica protein kinase, putative 0.0088 0.2125 1
Brugia malayi hypothetical protein 0.0228 0.5667 0.7758
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0424 0.0571
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.002 0.0424 0.0623
Leishmania major 4-coumarate:coa ligase-like protein 0.0069 0.166 0.7562
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.5667 0.5667
Schistosoma mansoni nuclear receptor 0.0005 0.0026 0.0019
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.002 0.0424 0.0424
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0181 0.4483 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0005 0.0026 0.0025
Brugia malayi nuclear receptor RXR 0.0005 0.004 0.0045
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.002 0.0424 0.0479
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.007 0.0141
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0052 0.1218 0.2457
Schistosoma mansoni cpg binding protein 0.0028 0.0618 0.0611
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.1696 0.1696
Brugia malayi transcription factor E74 isoform 0.001 0.0169 0.0222
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0069 0.166 0.3479
Mycobacterium ulcerans acyl-CoA synthetase 0.0069 0.166 0.3479
Mycobacterium ulcerans oxidoreductase 0.0012 0.0219 0.0151
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0086 0.0086
Brugia malayi conserved hypotetical protein 0.0005 0.0026 0.0025
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.002 0.0424 0.0479
Brugia malayi nuclear receptor NHR-88 0.0005 0.0026 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0154 0.0328
Echinococcus granulosus thyroid hormone receptor alpha 0.0005 0.0026 0.0026
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.002 0.0424 0.0623
Echinococcus multilocularis tumor protein p63 0.0331 0.8245 0.8245
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0156 0.0204
Loa Loa (eye worm) hypothetical protein 0.0052 0.1218 0.1659
Brugia malayi Pax transcription activation domain interacting protein 0.001 0.0154 0.0201
Leishmania major acetyl-CoA synthetase, putative 0.002 0.0424 0.1072
Loa Loa (eye worm) hypothetical protein 0.001 0.0156 0.0204
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.218 0.218
Loa Loa (eye worm) hypothetical protein 0.0005 0.004 0.0045
Brugia malayi AMP-binding enzyme family protein 0.002 0.0424 0.0571
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.1084 0.1476
Leishmania major acetyl-CoA synthetase, putative 0.002 0.0424 0.1072
Brugia malayi ecdysone receptor 0.0005 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Echinococcus multilocularis geminin 0.0167 0.4115 0.4115
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0012 0.0219 0.0151
Loa Loa (eye worm) hypothetical protein 0.001 0.0156 0.0204
Loa Loa (eye worm) hypothetical protein 0.0012 0.0219 0.0291
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0012 0.0219 0.0151
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0156 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0156 0.0204
Brugia malayi AMP-binding enzyme family protein 0.0069 0.166 0.2266
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0424 0.0623
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0048 0.113 0.1539
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0156 0.0156
Chlamydia trachomatis oxoacy-ACP reductase 0.0012 0.0219 0.0151
Loa Loa (eye worm) hypothetical protein 0.001 0.0156 0.0204
Loa Loa (eye worm) hypothetical protein 0.0034 0.0755 0.1026
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.1146 0.2174
Onchocerca volvulus 0.0148 0.3637 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0219 0.0151
Echinococcus multilocularis nibrin 0.001 0.0154 0.0154
Brugia malayi hypothetical protein 0.001 0.0154 0.0201
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Echinococcus multilocularis dnaJ subfamily B 0.04 1 1
Echinococcus multilocularis GPCR, family 2 0.0016 0.0301 0.0301
Onchocerca volvulus 0.0047 0.1084 0.2966
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0156 0.0204
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0424 0.0623
Onchocerca volvulus 0.001 0.0156 0.0409
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0012 0.0219 0.0212
Echinococcus multilocularis protein C ets 2 0.001 0.0169 0.0169
Brugia malayi AMP-binding enzyme family protein 0.002 0.0424 0.0571
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0156 0.0204
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.1413 0.1406
Schistosoma mansoni hypothetical protein 0.0016 0.0301 0.0294
Loa Loa (eye worm) DR-78 0.0005 0.0026 0.0025
Schistosoma mansoni hypothetical protein 0.04 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.007 0.0141
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.007 0.0141
Schistosoma mansoni ets 0.001 0.0169 0.0162
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0005 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.001 0.0156 0.0204
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0154 0.0328
Onchocerca volvulus 0.0069 0.166 0.4553
Schistosoma mansoni thyroid hormone receptor 0.001 0.0156 0.0149
Schistosoma mansoni ets-related 0.0215 0.5333 0.533
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0088 0.2125 0.2903
Loa Loa (eye worm) hypothetical protein 0.0069 0.166 0.2266
Schistosoma mansoni elf1 0.001 0.0169 0.0162
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0156 0.0204
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0156 0.0204
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Loa Loa (eye worm) hypothetical protein 0.001 0.0169 0.0222
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0154 0.0328
Loa Loa (eye worm) hypothetical protein 0.001 0.0154 0.0201
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0004 0.0007 0.0007
Brugia malayi nuclear receptor NHR-88 0.001 0.0156 0.0204
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0086 0.0079
Loa Loa (eye worm) hypothetical protein 0.0069 0.166 0.2266
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0301 0.0301
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0181 0.4483 1
Echinococcus multilocularis cpg binding protein 0.003 0.0659 0.0659
Echinococcus multilocularis muscleblind protein 0.0293 0.7302 0.7302
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0129 0.0129
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0169 0.0162
Brugia malayi AMP-binding enzyme family protein 0.0069 0.166 0.2266
Schistosoma mansoni topbp1 0.001 0.0154 0.0147
Brugia malayi acetyl-Coenzyme A synthetase 2 0.002 0.0424 0.0571
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0156 0.0409
Loa Loa (eye worm) hypothetical protein 0.0005 0.004 0.0045
Loa Loa (eye worm) hypothetical protein 0.001 0.0156 0.0204
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0301 0.0403
Onchocerca volvulus 0.0005 0.0026 0.0051
Loa Loa (eye worm) hypothetical protein 0.001 0.0156 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.007 0.0141
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.166 0.3379
Schistosoma mansoni hypothetical protein 0.0047 0.1084 0.1077
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0012 0.0219 0.0151
Echinococcus granulosus cpg binding protein 0.003 0.0659 0.0659
Loa Loa (eye worm) oxidoreductase 0.0012 0.0219 0.0291
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.1146 0.2174
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0088 0.2125 1
Plasmodium vivax acetyl-CoA synthetase, putative 0.002 0.0424 0.0623
Brugia malayi CXXC zinc finger family protein 0.0028 0.0618 0.0838
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0004 0.0007 0.0007
Brugia malayi steroid hormone receptor 0.001 0.0156 0.0204
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0069 0.166 0.3379
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0004 0.0007 0.0007
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0005 0.0026 0.0026
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0012 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0069 0.166 0.2266
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0156 0.0204
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.0169 0.0222
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0156 0.0156
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.0219 0.0151
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0156 0.0156
Schistosoma mansoni hypothetical protein 0.001 0.0169 0.0162
Trypanosoma brucei oxidoreductase-like protein 0.0012 0.0219 0.0332
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0012 0.0219 0.1002
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0005 0.0026 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0424 0.0623
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.0154 0.0328
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0005 0.0026 0.0025
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0181 0.4483 1
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.5667 0.5667
Schistosoma mansoni hypothetical protein 0.0016 0.0301 0.0294
Onchocerca volvulus 0.002 0.0424 0.1147
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0219 0.0151
Entamoeba histolytica acyl-CoA synthetase, putative 0.0069 0.166 0.7807
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0005 0.0026 0.0026
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.1146 0.2174
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.007 0.0141
Loa Loa (eye worm) fli-1 protein 0.0215 0.5333 0.7302
Toxoplasma gondii propionate-CoA ligase 0.002 0.0424 0.0623
Loa Loa (eye worm) hypothetical protein 0.001 0.0156 0.0204
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.218 0.218
Brugia malayi topoisomerase 0.001 0.0154 0.0201
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.004 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0154 0.0328
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0004 0.0007 0.0007
Echinococcus granulosus nibrin 0.001 0.0154 0.0154
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0069 0.166 0.3479
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0004 0.0007 0.0007
Mycobacterium ulcerans hypothetical protein 0.0069 0.166 0.3479
Loa Loa (eye worm) hypothetical protein 0.0016 0.0301 0.0403
Brugia malayi Ets-domain containing protein 0.0071 0.1696 0.2315
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0156 0.0156
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Loa Loa (eye worm) hypothetical protein 0.0005 0.004 0.0045
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0301 0.0301
Schistosoma mansoni survival motor neuron protein 0.0047 0.1084 0.1077
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.002 0.0424 0.0479
Echinococcus multilocularis expressed protein 0.0004 0.0007 0.0007
Brugia malayi nuclear receptor NHR-67 0.0005 0.0026 0.0025
Echinococcus granulosus Nuclear hormone receptor HR96 0.0005 0.0026 0.0026
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0156 0.0156
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.218 0.2978
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.002 0.0424 0.1368
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0154 0.0328
Echinococcus multilocularis nuclear receptor nhr 48 0.0005 0.0026 0.0026
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0156 0.0149
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.218 0.218
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0154 0.0154
Echinococcus granulosus ETS domain containing protein Elk 1 0.001 0.0169 0.0169
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.001 0.0154 0.0201
Schistosoma mansoni hypothetical protein 0.0034 0.0755 0.0749
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0169 0.0169
Trichomonas vaginalis hypothetical protein 0.0181 0.4483 1
Brugia malayi hypothetical protein 0.0005 0.004 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0156 0.0204
Loa Loa (eye worm) hypothetical protein 0.0005 0.004 0.0045
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0088 0.2125 1
Brugia malayi nuclear hormone receptor 0.0005 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0004 0.0007 0.0007
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0169 0.0222
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0424 0.0479
Plasmodium falciparum acetyl-CoA synthetase, putative 0.002 0.0424 0.0623
Loa Loa (eye worm) AMP-binding enzyme family protein 0.002 0.0424 0.0571
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0219 0.0151
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0156 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0154 0.0328
Echinococcus multilocularis dual specificity 0.0088 0.2125 0.2125
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0156 0.0149
Loa Loa (eye worm) hypothetical protein 0.001 0.0154 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0154 0.0328
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.002 0.0424 0.1368
Echinococcus granulosus muscleblind protein 0.0293 0.7302 0.7302
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.1696 0.2315
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.007 0.0141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0156 0.0204
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0026 0.0025
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0012 0.0219 0.0151
Echinococcus granulosus tumor protein p63 0.0331 0.8245 0.8245
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0156 0.0156
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0004 0.0007 0.0007
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0156 0.0409
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Entamoeba histolytica protein kinase domain containing protein 0.0088 0.2125 1
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0156 0.0149
Echinococcus granulosus geminin 0.0167 0.4115 0.4115
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0005 0.0026 0.0025
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0026 0.0019
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.002 0.0424 0.1368
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0026 0.0025
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0156 0.0149
Schistosoma mansoni acetyl-CoA synthetase 0.002 0.0424 0.0417
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0219 0.0151
Onchocerca volvulus 0.002 0.0424 0.1147
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0005 0.004 0.004
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.002 0.0424 0.1368
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.007 0.0141
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0012 0.0219 0.0332
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.007 0.0141
Treponema pallidum DNA ligase (lig) 0.001 0.0154 0.5
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.004 0.0032
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.1147 0.1562
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.218 0.2174
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0012 0.0219 0.0219
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0424 0.0623
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.218 0.2978
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0156 0.0149
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0219 0.0151
Mycobacterium ulcerans acetyl-CoA synthetase 0.002 0.0424 0.0623
Echinococcus granulosus GPCR family 2 0.0016 0.0301 0.0301
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0156 0.0156
Echinococcus multilocularis ETS transcription factor Elf 5 0.001 0.0169 0.0169
Schistosoma mansoni thyroid hormone receptor 0.001 0.0156 0.0149
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0352 0.0311
Schistosoma mansoni hypothetical protein 0.0167 0.4115 0.4111
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.0219 0.0151
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.007 0.0141
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0169 0.0222
Trichomonas vaginalis antibiotic synthetase, putative 0.002 0.0424 0.093
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0219 0.0151
Schistosoma mansoni nuclear receptor nhr-48 0.0005 0.0026 0.0019
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0156 0.0409
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.007 0.0141
Onchocerca volvulus 0.0048 0.113 0.3092
Plasmodium falciparum acyl-CoA synthetase 0.0052 0.1218 0.2457
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0156 0.0156
Giardia lamblia Replication factor C, subunit 1 0.001 0.0154 0.5
Schistosoma mansoni hypothetical protein 0.0167 0.4115 0.4111
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0156 0.0204
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.002 0.0424 0.0623
Schistosoma mansoni cpg binding protein 0.003 0.0659 0.0652
Loa Loa (eye worm) hypothetical protein 0.001 0.0154 0.0201
Echinococcus granulosus ETS transcription factor Elf 1 0.001 0.0169 0.0169
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0069 0.166 0.3479
Loa Loa (eye worm) hypothetical protein 0.001 0.0154 0.0201
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0154 0.0328
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.218 0.2174
Loa Loa (eye worm) hypothetical protein 0.0148 0.3637 0.4977
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0618 0.0838
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.1147 0.1562
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0012 0.0219 0.0151
Trypanosoma brucei acetyl-CoA synthetase, putative 0.002 0.0424 0.1368
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0069 0.166 0.3479
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0156 0.0149
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.002 0.0424 0.0623
Brugia malayi orphan nuclear receptor NR2E1 0.0005 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0005 0.004 0.0045
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.002 0.0424 0.0623
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.002 0.0424 0.0479
Brugia malayi AMP-binding enzyme family protein 0.002 0.0424 0.0571
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0005 0.0026 0.0051
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.002 0.0424 0.0623
Brugia malayi ecdysteroid receptor 0.001 0.0156 0.0204
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.001 0.0156 0.0204
Mycobacterium ulcerans acyl-CoA synthetase 0.0069 0.166 0.3479
Echinococcus granulosus nuclear receptor nhr 48 0.0005 0.0026 0.0026
Loa Loa (eye worm) nuclear hormone receptor 0.0005 0.0026 0.0025
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.002 0.0424 0.0479
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0004 0.0007 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0156 0.0204
Schistosoma mansoni dihydropteridine reductase 0.0012 0.0219 0.0212
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0005 0.004 0.004
Echinococcus granulosus FTZ F1 alpha 0.001 0.0156 0.0156
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0012 0.0219 0.0151
Schistosoma mansoni nuclear receptor 0.0005 0.0026 0.0019
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0126 0.0163
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0156 0.0204
Brugia malayi hypothetical protein 0.0005 0.0026 0.0025
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0181 0.4483 1
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.002 0.0424 0.0623
Echinococcus granulosus Nuclear hormone receptor HR96 0.0005 0.0026 0.0026
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.002 0.0424 0.0424
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0181 0.4483 1
Onchocerca volvulus 0.0012 0.0219 0.0585
Schistosoma mansoni nuclear hormone receptor 0.001 0.0156 0.0149
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.004 0.0045
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0005 0.004 0.0045
Loa Loa (eye worm) hypothetical protein 0.0049 0.1147 0.1562
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.002 0.0424 0.0623
Schistosoma mansoni zinc finger protein 0.0005 0.0026 0.0019
Brugia malayi Ets-domain containing protein 0.0071 0.1696 0.2315
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Brugia malayi nuclear hormone receptor family member odr-7 0.0005 0.0026 0.0025
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0156 0.0149
Echinococcus multilocularis ETS domain containing protein Elk 1 0.001 0.0169 0.0169
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0012 0.0219 0.0151
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0129 0.0129
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0424 0.0479
Schistosoma mansoni hypothetical protein 0.0016 0.0301 0.0294
Loa Loa (eye worm) hypothetical protein 0.0005 0.0026 0.0025
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.002 0.0424 0.0623
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0424 0.0623
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0156 0.0204
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0012 0.0219 0.0332
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0156 0.0156
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0012 0.0219 0.0151
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0181 0.4483 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0005 0.0026 0.0026
Echinococcus granulosus ewsr:fli fusion protein type 0.001 0.0169 0.0169
Schistosoma mansoni coup transcription factor 0.001 0.0156 0.0149
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0156 0.0204
Onchocerca volvulus 0.0005 0.0026 0.0051
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.218 0.218
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0156 0.0204
Loa Loa (eye worm) hypothetical protein 0.0228 0.5667 0.7758
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.007 0.0141
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0424 0.0623
Brugia malayi hypothetical protein 0.0005 0.004 0.0045
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0005 0.004 0.0032
Brugia malayi DKFZp564C0469 protein 0.001 0.0154 0.0201
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.1147 0.1562
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.2125 0.2119
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0012 0.0219 0.0332
Loa Loa (eye worm) hypothetical protein 0.001 0.0154 0.0201
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0219 0.0151
Loa Loa (eye worm) hypothetical protein 0.0052 0.1218 0.1659
Entamoeba histolytica acyl-CoA synthetase, putative 0.0069 0.166 0.7807
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.0219 0.0151
Brugia malayi Protein kinase domain containing protein 0.0088 0.2125 0.2903
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0156 0.0149
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.002 0.0424 0.0623
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.002 0.0424 0.1072
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0169 0.0169
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.007 0.0141
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0004 0.0007 0.0007
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0156 0.0156
Brugia malayi nuclear receptor RXR 0.0005 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0052 0.1218 0.1659
Echinococcus multilocularis muscleblind protein 1 0.0293 0.7302 0.7302
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0154 0.0328
Loa Loa (eye worm) oxidoreductase 0.002 0.0424 0.0571
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0424 0.0623
Brugia malayi nuclear hormone receptor 0.001 0.0156 0.0204
Schistosoma mansoni DNA ligase IV 0.001 0.0154 0.0147
Onchocerca volvulus 0.0012 0.0219 0.0585
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.007 0.0141
Onchocerca volvulus 0.002 0.0424 0.1147
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0156 0.0204
Loa Loa (eye worm) hypothetical protein 0.0052 0.1218 0.1659
Echinococcus granulosus protein C ets 2 0.001 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0087 0.2113 0.2887
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.007 0.0141
Brugia malayi nuclear hormone receptor family member nhr-6 0.0005 0.0026 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0004 0.0011 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.007 0.0141
Schistosoma mansoni topbp1 0.001 0.0154 0.0147
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0012 0.0219 0.0291
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0088 0.2125 1
Trichomonas vaginalis antibiotic synthetase, putative 0.002 0.0424 0.093
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.1146 0.2174
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0156 0.0204
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0181 0.4483 1
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0301 0.0403
Trichomonas vaginalis helicase, putative 0.0006 0.007 0.0141
Brugia malayi hypothetical protein 0.0148 0.3637 0.4977
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.002 0.0424 0.1368
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0424 0.0479
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0005 0.0026 0.0051
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.002 0.0424 0.0479
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Entamoeba histolytica hypothetical protein 0.001 0.0154 0.0693
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0005 0.0026 0.0026
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.002 0.0424 0.1967
Trypanosoma brucei pteridine reductase 1 0.0012 0.0219 0.0332
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.1696 0.1696
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0156 0.0204
Brugia malayi hypothetical protein 0.001 0.0154 0.0201
Loa Loa (eye worm) retinol dehydrogenase 12 0.0012 0.0219 0.0291
Loa Loa (eye worm) hypothetical protein 0.0293 0.7302 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.218 0.2174
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.002 0.0424 0.0623
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0301 0.0301
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0004 0.0007 0.0007
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0169 0.0169
Schistosoma mansoni ets-related 0.001 0.0169 0.0162
Loa Loa (eye worm) hypothetical protein 0.0087 0.2113 0.2887
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0169 0.0222
Echinococcus multilocularis ETS transcription factor Elf 1 0.001 0.0169 0.0169
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0169 0.0169
Plasmodium vivax acyl-CoA synthetase, putative 0.0052 0.1218 0.2457
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0219 0.0151
Onchocerca volvulus 0.001 0.0154 0.0404
Echinococcus multilocularis ets variant gene 4 0.001 0.0169 0.0169
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.002 0.0424 0.0623
Onchocerca volvulus 0.002 0.0424 0.1147
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0005 0.0026 0.0026
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0156 0.0156
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0156 0.0156
Echinococcus granulosus replication factor c subunit 1 0.001 0.0154 0.0154
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.0219 0.0151
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0156 0.0204
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0156 0.0156
Loa Loa (eye worm) AMP-binding enzyme family protein 0.002 0.0424 0.0571
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0219 0.0151
Schistosoma mansoni cpg binding protein 0.003 0.0659 0.0652
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0086 0.0086
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.113 0.1123
Entamoeba histolytica protein kinase, putative 0.0088 0.2125 1
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.0219 0.0151

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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