Detailed information for compound 571672

Basic information

Technical information
  • TDR Targets ID: 571672
  • Name: [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-di hydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy- phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphon amidic acid
  • MW: 506.196 | Formula: C10H17N6O12P3
  • H donors: 7 H acceptors: 11 LogP: -6 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 4
  • SMILES: O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)N)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N
  • InChi: 1S/C10H17N6O12P3/c11-8-5-9(14-2-13-8)16(3-15-5)10-7(18)6(17)4(26-10)1-25-30(21,22)28-31(23,24)27-29(12,19)20/h2-4,6-7,10,17-18H,1H2,(H,21,22)(H,23,24)(H2,11,13,14)(H3,12,19,20)/t4-,6-,7-,10-/m1/s1
  • InChiKey: FCPWHIOZHGINMV-KQYNXXCUSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-2-tetrahydrofuranyl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxyphosphonamidic acid
  • [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonamidic acid
  • [[[(2R,3S,4R,5R)-5-adenin-9-yl-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonamidic acid
  • [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxyphosphonamidic acid
  • ATP-gamma amidate
  • [[[(2R,3S,4R,5R)-5-(6-amino-9-purinyl)-3,4-dihydroxy-2-tetrahydrofuranyl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxyphosphonamidic acid
  • 58430-80-1
  • Adenosine 5'-(trihydrogen diphosphate), monoanhydride with phosphoramidic acid
  • Adenosine triphosphate-gamma amidate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0077 0.1143
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0058 0.0245
Brugia malayi beta-lactamase 0.0039 0.0057 0.0071
Onchocerca volvulus 0.0031 0.004 0.0046
Brugia malayi hypothetical protein 0.0123 0.0243 0.0304
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0111 0.0105
Leishmania major 4-coumarate:coa ligase-like protein 0.0031 0.004 0.0254
Echinococcus multilocularis Smad4 0.0024 0.0024 0.0019
Onchocerca volvulus 0.0103 0.0199 0.0245
Trichomonas vaginalis set domain proteins, putative 0.1017 0.2224 0.9481
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0057 0.0241
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0026 0.0032
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0029 0.0035 0.022
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0057 0.0052
Plasmodium falciparum ferrodoxin reductase-like protein 0.0029 0.0035 0.0502
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0097 0.0629
Brugia malayi hypothetical protein 0.0334 0.071 0.0887
Schistosoma mansoni importin beta-1 0.0057 0.0097 0.012
Loa Loa (eye worm) transcription factor SMAD2 0.0356 0.0759 0.0949
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.015 0.0302 0.0366
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0029 0.0035 0.0029
Onchocerca volvulus Phospholipase A2 homolog 0.086 0.1877 0.2343
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0109 0.0212 1
Schistosoma mansoni hypothetical protein 0.015 0.0302 0.0372
Toxoplasma gondii selenide, water dikinase 0.0029 0.0035 0.0502
Onchocerca volvulus 0.0052 0.0085 0.0103
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0116 0.0228 0.1487
Schistosoma mansoni RAR-like nuclear receptor 0.0457 0.0982 0.1211
Giardia lamblia Fructose-bisphosphate aldolase 0.1072 0.2346 1
Echinococcus granulosus aryl hydrocarbon receptor 0.0052 0.0086 0.0099
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0109 0.0212 0.0784
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0073 0.0308
Plasmodium falciparum endoplasmic reticulum oxidoreductin, putative 0.0051 0.0084 0.1242
Plasmodium vivax importin-beta 2, putative 0.0057 0.0097 0.1436
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0011 0.0033
Brugia malayi Peptidase family C54 containing protein 0.0116 0.0228 0.0284
Brugia malayi hypothetical protein 0.0037 0.0051 0.0064
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0051 0.0187
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0035 0.0145
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0057 0.0368
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Onchocerca volvulus Protein ultraspiracle homolog 0.0457 0.0982 0.1225
Schistosoma mansoni hypothetical protein 0.0048 0.0078 0.0096
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.006 0.0386
Schistosoma mansoni lipoxygenase 0.0341 0.0726 0.0895
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0109 0.0212 0.1386
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0051 0.0128
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0077 0.0097
Schistosoma mansoni inositol monophosphatase 0.004 0.006 0.0074
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Trypanosoma cruzi DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.005
Trypanosoma cruzi polo-like protein kinase, putative 0.0701 0.1524 1
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0029 0.0035 0.022
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0109 0.0212 0.1386
Trichomonas vaginalis maltase-glucoamylase, putative 0.0015 0.0003 0.001
Leishmania major hypothetical protein, conserved 0.0029 0.0035 0.022
Loa Loa (eye worm) hypothetical protein 0.0152 0.0308 0.0384
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0005 0.0018
Leishmania major 4-coumarate:coa ligase-like protein 0.0031 0.004 0.0254
Echinococcus multilocularis neuropeptide s receptor 0.1397 0.3067 0.3063
Trichomonas vaginalis CAMK family protein kinase 0.0701 0.1524 0.6497
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0078 0.0142 0.0178
Schistosoma mansoni cpg binding protein 0.0066 0.0117 0.0145
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0077 0.0501
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Schistosoma mansoni methyl-cpg binding protein mbd 0.0023 0.0021 0.0026
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0048 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0029 0.0035 0.022
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.012 0.0414
Echinococcus multilocularis glutamate synthase 0.0029 0.0035 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0701 0.1524 0.6497
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0028 0.0035
Brugia malayi AMP-binding enzyme family protein 0.0031 0.004 0.005
Loa Loa (eye worm) hypothetical protein 0.0097 0.0186 0.0233
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0011 0.0063
Loa Loa (eye worm) hypothetical protein 0.0036 0.0051 0.0063
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0057 0.0839
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1072 0.2346 1
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0005 0.0018
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0029 0.0035 0.022
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.005
Entamoeba histolytica Ran family GTPase 0.0042 0.0064 0.0258
Loa Loa (eye worm) hypothetical protein 0.0457 0.0982 0.1228
Brugia malayi orphan nuclear receptor NR2E1 0.0123 0.0243 0.0304
Giardia lamblia Thioredoxin reductase 0.0029 0.0035 0.0102
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.0031 0.0035
Trypanosoma brucei pol-associated gene 1 0.0051 0.0084 0.0544
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.012 0.0403
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1072 0.2346 1
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0008 0.0002
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0029 0.0035 0.0135
Trypanosoma cruzi trypanothione reductase, putative 0.0315 0.0668 0.438
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.006 0.0253
Mycobacterium ulcerans DNA polymerase IV 0.0025 0.0027 0.0018
Leishmania major hypothetical protein, conserved 0.0236 0.0494 0.3238
Schistosoma mansoni hypothetical protein 0.0029 0.0035 0.0043
Onchocerca volvulus 0.0078 0.0142 0.0174
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0003 0.001
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0083 0.0155 0.0185
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0029 0.0035 0.0063
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.0524 0.2081
Brugia malayi glutamate synthase 0.0029 0.0035 0.0043
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0023 0.0021 0.0016
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0058 0.0245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Onchocerca volvulus 0.0097 0.0186 0.0229
Schistosoma mansoni cpg binding protein 0.0066 0.0117 0.0145
Echinococcus granulosus smad 0.0024 0.0024 0.0023
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0057 0.0155
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0008 0.0101
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0074 0.0135 0.2012
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.015 0.0302 0.0297
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0029 0.0035 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Brugia malayi ecdysone receptor 0.0123 0.0243 0.0304
Loa Loa (eye worm) steroid hormone receptor 0.0457 0.0982 0.1228
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0894 0.1951 0.2439
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0457 0.0982 0.1211
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.0365 0.036
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0011 0.0063
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0116 0.0228 0.0968
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0029 0.0035 0.0043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1072 0.2346 1
Brugia malayi MH2 domain containing protein 0.0024 0.0024 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0457 0.0982 0.1228
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0058 0.0072
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0037 0.0051 0.0064
Brugia malayi conserved hypotetical protein 0.0123 0.0243 0.0304
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0025 0.0027 0.0021
Onchocerca volvulus Serine\/threonine kinase homolog 0.0701 0.1524 0.1902
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0334 0.071 0.0869
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0109 0.0212 0.1386
Loa Loa (eye worm) hypothetical protein 0.0457 0.0982 0.1228
Echinococcus granulosus cpg binding protein 0.0066 0.0117 0.0138
Echinococcus granulosus lysine specific demethylase 5A 0.0069 0.0124 0.0146
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0152 0.0308 0.0379
Schistosoma mansoni lipoxygenase 0.0201 0.0416 0.0513
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0008 0.0003
Schistosoma mansoni nuclear hormone receptor 0.0457 0.0982 0.1211
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0011 0.0013
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0011 0.0143
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0109 0.0212 0.1386
Brugia malayi PHD-finger family protein 0.0037 0.0052 0.0065
Echinococcus granulosus methyl CpG binding domain protein 2 0.0023 0.0021 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0129 0.0257 0.0317
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.001
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0077 0.1143
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0029 0.0035 0.0036
Brugia malayi Nuclear hormone receptor-like 1 0.0457 0.0982 0.1228
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0116 0.0228 0.0968
Schistosoma mansoni tar DNA-binding protein 0.0411 0.0882 0.1087
Toxoplasma gondii histone lysine methyltransferase SET1 0.0122 0.0241 0.3597
Trichomonas vaginalis glutamate synthase, putative 0.0029 0.0035 0.0145
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0457 0.0982 0.0977
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0029 0.0035 0.0502
Loa Loa (eye worm) hypothetical protein 0.0039 0.0057 0.0071
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0029 0.0035 0.0145
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0123 0.0243 0.0238
Trypanosoma brucei glucosidase, putative 0.004 0.0058 0.0374
Echinococcus granulosus glutamate synthase 0.0029 0.0035 0.0036
Treponema pallidum NADH oxidase 0.0109 0.0212 0.0769
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0058 0.0245
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0109 0.0212 0.1386
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.015 0.0302 0.0377
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0025 0.0027 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0048 0.031
Onchocerca volvulus 0.0078 0.0142 0.0174
Schistosoma mansoni hypothetical protein 0.0021 0.0016 0.002
Entamoeba histolytica serine/threonine protein kinase, putative 0.0701 0.1524 0.6493
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0074 0.0135 0.0478
Entamoeba histolytica hypothetical protein 0.0046 0.0073 0.0299
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0029 0.0035 0.0051
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0097 0.0629
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0001 0.0001
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0008 0.0101
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0011 0.0063
Echinococcus multilocularis musashi 0.0026 0.0028 0.0023
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0064 0.0935
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0048 0.0193
Echinococcus multilocularis FTZ F1 alpha 0.0457 0.0982 0.0977
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0029 0.0035 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1072 0.2346 1
Echinococcus multilocularis Endoplasmic reticulum oxidoreductin 1 0.0051 0.0084 0.0078
Plasmodium falciparum thioredoxin reductase 0.0109 0.0212 0.3164
Brugia malayi glutaminase DH11.1 0.0299 0.0633 0.0791
Schistosoma mansoni tar DNA-binding protein 0.0411 0.0882 0.1087
Brugia malayi Nuclear hormone receptor E75 0.0123 0.0243 0.0304
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.015 0.0302 0.0366
Echinococcus granulosus geminin 0.1139 0.2495 0.3071
Onchocerca volvulus Protein cycle homolog 0.0037 0.0051 0.0061
Brugia malayi PAS domain containing protein 0.0016 0.0005 0.0006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.012 0.0403
Schistosoma mansoni nuclear hormone receptor 0.0123 0.0243 0.03
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0025 0.0027 0.003
Echinococcus multilocularis dnaJ subfamily B 0.0859 0.1874 0.187
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0003 0.0013
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0036 0.0051 0.0063
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0123 0.0243 0.0238
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0457 0.0982 0.1211
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.004 0.0072
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0011 0.0005
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Leishmania major protein kinase, putative 0.0018 0.001 0.0058
Echinococcus granulosus intermediate filament protein 0.0026 0.0028 0.0028
Schistosoma mansoni autophagin-1 (C54 family) 0.0116 0.0228 0.0281
Onchocerca volvulus 0.0039 0.0057 0.0068
Trypanosoma brucei DNA polymerase eta, putative 0.0025 0.0027 0.0167
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0109 0.0212 0.1386
Brugia malayi Glycosyl hydrolases family 31 protein 0.0178 0.0365 0.0456
Giardia lamblia NADH oxidase lateral transfer candidate 0.0109 0.0212 0.0863
Echinococcus multilocularis ecdysone induced protein 78C 0.0457 0.0982 0.0977
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0057 0.0368
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0058 0.0065
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0058 0.0235
Loa Loa (eye worm) DR-78 0.0123 0.0243 0.0304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0411 0.0882 0.1102
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.006 0.0054
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.005
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.004 0.0072
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0045 0.0071 0.0457
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0027 0.0031 0.0047
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0457 0.0982 0.1205
Trypanosoma brucei unspecified product 0.0025 0.0027 0.0167
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0718 0.1562 0.638
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0031 0.0194
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0457 0.0982 0.1228
Mycobacterium ulcerans glutamate synthase subunit beta 0.0029 0.0035 0.0051
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0457 0.0982 0.1211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0008 0.001
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0109 0.0212 0.1386
Schistosoma mansoni ran 0.0042 0.0064 0.0078
Brugia malayi serine/threonine-protein kinase plk-2 0.0701 0.1524 0.1905
Trypanosoma brucei glycosyl hydrolase-like protein 0.0015 0.0003 0.0013
Loa Loa (eye worm) hypothetical protein 0.0061 0.0105 0.0131
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0341 0.0726 0.0888
Plasmodium vivax SET domain protein, putative 0.0129 0.0257 0.3835
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0058 0.0053
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0032 0.0039
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0003 0.001
Brugia malayi Pre-SET motif family protein 0.0894 0.1951 0.2439
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0315 0.0668 0.2674
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0057 0.0241
Plasmodium falciparum thioredoxin reductase 0.0315 0.0668 1
Schistosoma mansoni smad1 5 8 and 0.0024 0.0024 0.003
Echinococcus multilocularis tar DNA binding protein 0.0411 0.0882 0.0877
Toxoplasma gondii thioredoxin reductase 0.0315 0.0668 1
Brugia malayi isocitrate dehydrogenase 0.0048 0.0077 0.0097
Trypanosoma cruzi DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0457 0.0982 0.1228
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0016 0.0005 0.0018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0014 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0701 0.1524 0.6497
Trypanosoma cruzi DNA polymerase eta, putative 0.0025 0.0027 0.0167
Schistosoma mansoni alpha glucosidase 0.004 0.0058 0.0072
Brugia malayi nuclear hormone receptor 0.0123 0.0243 0.0304
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0064 0.041
Echinococcus granulosus nuclear receptor nhr 48 0.0123 0.0243 0.0293
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0029 0.0035 0.022
Entamoeba histolytica acyl-CoA synthetase, putative 0.0031 0.004 0.0157
Echinococcus multilocularis zinc finger protein 0.003 0.0036 0.0031
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.0264 0.0326
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0718 0.1562 0.6358
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0029 0.0035 0.0145
Trichomonas vaginalis CAMK family protein kinase 0.0701 0.1524 0.6497
Loa Loa (eye worm) hypothetical protein 0.015 0.0302 0.0377
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0027 0.0031 0.0035
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0029 0.0035 0.022
Brugia malayi nuclear hormone receptor 0.0457 0.0982 0.1228
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0003 0.001
Mycobacterium ulcerans DNA polymerase IV 0.0025 0.0027 0.0018
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0029 0.0035 0.0036
Loa Loa (eye worm) glutaminase 2 0.0299 0.0633 0.0791
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0057 0.0071
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0178 0.0365 0.0456
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0457 0.0982 0.1228
Loa Loa (eye worm) nuclear hormone receptor 0.0123 0.0243 0.0304
Echinococcus granulosus lipoxygenase domain containing protein 0.0078 0.0142 0.0169
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0011 0.0063
Echinococcus multilocularis nuclear receptor nhr 48 0.0123 0.0243 0.0238
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0109 0.0212 0.1386
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0123 0.0243 0.03
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0008 0.0044
Mycobacterium leprae Probable lipase LipE 0.0039 0.0057 0.0214
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0048 0.0078 0.0089
Loa Loa (eye worm) latrophilin receptor protein 2 0.015 0.0302 0.0377
Echinococcus granulosus inositol monophosphatase 1 0.004 0.006 0.0067
Plasmodium falciparum glutathione reductase 0.0109 0.0212 0.3164
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.005 0.0211
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0473 0.1019 0.1273
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0008 0.0003
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0123 0.0243 0.0238
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0077 0.0501
Brugia malayi Nuclear hormone receptor E75 0.0123 0.0243 0.0304
Echinococcus multilocularis mixed lineage leukemia protein mll 0.002 0.0014 0.0009
Leishmania major DNA polymerase eta, putative 0.0025 0.0027 0.0167
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0057 0.0214
Schistosoma mansoni tar DNA-binding protein 0.0411 0.0882 0.1087
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0129 0.0257 0.0252
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0011 0.0013
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0057 0.007
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0057 0.0064
Mycobacterium tuberculosis Probable dehydrogenase 0.0718 0.1562 0.6358
Brugia malayi hypothetical protein 0.0123 0.0243 0.0304
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0302 0.064 0.0783
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0111 0.013
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0008 0.001
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.1117 0.2446 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0057 0.0071
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0057 0.0241
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0457 0.0982 0.0977
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0109 0.0212 0.3164
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0011 0.0063
Brugia malayi nuclear receptor NHR-67 0.0123 0.0243 0.0304
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0031 0.004 0.0084
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0116 0.0228 0.0968
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0034 0.0045 0.0039
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0023 0.0022 0.0012
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0008 0.001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0457 0.0982 0.1205
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.0111 0.0105
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0022
Trichomonas vaginalis ran, putative 0.0042 0.0064 0.0268
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0025 0.0027 0.0167
Schistosoma mansoni lamin 0.0026 0.0028 0.0035
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0057 0.0241
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0334 0.071 0.0704
Entamoeba histolytica peptidase, C54 family 0.0045 0.0071 0.0289
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0077 0.0072
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0058 0.0245
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0109 0.0212 0.0207
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0029 0.0035 0.0051
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0302 0.064 0.0635
Loa Loa (eye worm) hypothetical protein 0.0334 0.071 0.0887
Loa Loa (eye worm) hypothetical protein 0.0052 0.0085 0.0107
Loa Loa (eye worm) hypothetical protein 0.0057 0.0097 0.0121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1072 0.2346 1
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0005 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.086 0.1877 0.2346
Onchocerca volvulus 0.006 0.0104 0.0126
Entamoeba histolytica peptidase, C54 family 0.0045 0.0071 0.0289
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0037 0.0051 0.0064
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.0124 0.0155
Leishmania major protein kinase, putative 0.0018 0.001 0.0058
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0011 0.0013
Brugia malayi Bromodomain containing protein 0.0104 0.0201 0.0251
Echinococcus granulosus snurportin 1 0.061 0.1321 0.1623
Loa Loa (eye worm) hypothetical protein 0.0457 0.0982 0.1228
Onchocerca volvulus 0.0039 0.0057 0.0068
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0123 0.0244 0.0294
Loa Loa (eye worm) hypothetical protein 0.0039 0.0057 0.0071
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0457 0.0982 0.1205
Schistosoma mansoni thyroid hormone receptor 0.0457 0.0982 0.1211
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0057 0.0241
Mycobacterium ulcerans hypothetical protein 0.0027 0.0031 0.0035
Entamoeba histolytica peptidase, C54 family 0.0116 0.0228 0.0959
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0028
Trypanosoma cruzi DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0457 0.0982 0.0977
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0123 0.0243 0.03
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0031 0.004 0.0072
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Echinococcus granulosus zinc finger protein 0.003 0.0036 0.0038
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.006 0.0881
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0152 0.0308 0.0379
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0029 0.0035 0.0502
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0028
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0123 0.0243 0.0238
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0064 0.041
Schistosoma mansoni alpha-glucosidase 0.0153 0.031 0.0383
Schistosoma mansoni microtubule-associated protein tau 0.3673 0.811 1
Loa Loa (eye worm) thioredoxin reductase 0.0315 0.0668 0.0835
Brugia malayi hypothetical protein 0.0078 0.0142 0.0178
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0029 0.0035 0.0063
Brugia malayi MH2 domain containing protein 0.0356 0.0759 0.0949
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0473 0.1019 0.1273
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0029 0.0035 0.0029
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.012 0.0141
Schistosoma mansoni hypothetical protein 0.1139 0.2495 0.3076
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0035 0.0145
Schistosoma mansoni smad1 5 8 and 0.0024 0.0024 0.003
Loa Loa (eye worm) RNA binding protein 0.0411 0.0882 0.1102
Brugia malayi hypothetical protein 0.0052 0.0085 0.0107
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.061 0.1321 0.1652
Trichomonas vaginalis apoptosis inducing factor, putative 0.0029 0.0035 0.0145
Onchocerca volvulus Bile acid receptor homolog 0.3623 0.7999 1
Trypanosoma brucei trypanothione reductase 0.0315 0.0668 0.438
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0701 0.1524 1
Echinococcus multilocularis geminin 0.1139 0.2495 0.249
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0029 0.0035 0.0063
Echinococcus multilocularis thioredoxin glutathione reductase 0.0317 0.0673 0.0668
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0074 0.0135 0.2012
Brugia malayi Steroid receptor seven-up type 2 0.0457 0.0982 0.1228
Brugia malayi MH1 domain containing protein 0.0024 0.0024 0.003
Schistosoma mansoni kinase 0.0356 0.076 0.0937
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0058 0.0245
Echinococcus granulosus L aminoadipate semialdehyde 0.0265 0.0557 0.068
Loa Loa (eye worm) doublecortin family protein 0.0078 0.0142 0.0178
Echinococcus granulosus lamin 0.0026 0.0028 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0457 0.0982 0.1228
Brugia malayi AMP-binding enzyme family protein 0.0031 0.004 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0701 0.1524 0.6497
Schistosoma mansoni nuclear receptor nhr-48 0.0123 0.0243 0.03
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0334 0.071 0.0887
Brugia malayi jmjC domain containing protein 0.0017 0.0008 0.001
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0023 0.0022 0.0834
Brugia malayi hypothetical protein 0.0334 0.071 0.0887
Leishmania major endoplasmic reticulum oxidoreductin, putative 0.0051 0.0084 0.0544
Brugia malayi Bromodomain containing protein 0.0051 0.0084 0.0105
Brugia malayi nuclear receptor RXR 0.0334 0.071 0.0887
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0025 0.0027 0.0111
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0029 0.0035 0.0102
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0029 0.0035 0.0502
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.006 0.0386
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0029 0.0035 0.0029
Entamoeba histolytica peptidase, C54 family 0.0045 0.0071 0.0289
Echinococcus multilocularis neuropeptide receptor A26 0.1397 0.3067 0.3063
Schistosoma mansoni loxhd1 0.0078 0.0142 0.0176
Schistosoma mansoni glutamate synthase 0.0029 0.0035 0.0043
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0302 0.064 0.08
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0057 0.0144
Plasmodium falciparum glutathione reductase 0.0315 0.0668 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0123 0.0243 0.0304
Brugia malayi hypothetical protein 0.0036 0.0051 0.0063
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0123 0.0243 0.03
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0016 0.0005 0.0018
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0058 0.0235
Brugia malayi Smad1 0.0024 0.0024 0.003
Brugia malayi ImpB/MucB/SamB family protein 0.0025 0.0027 0.0033
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0265 0.0557 0.0687
Leishmania major hypothetical protein, conserved 0.0039 0.0057 0.0368
Schistosoma mansoni glutaminase 0.0299 0.0633 0.078
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0058 0.0374
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0457 0.0982 0.1211
Brugia malayi nuclear hormone receptor family member nhr-6 0.0123 0.0243 0.0304
Leishmania major phosphopantetheinyl transferase-like protein 0.0074 0.0135 0.0881
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0457 0.0982 0.1228
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0029 0.0035 0.022
Echinococcus granulosus dna polymerase kappa 0.0025 0.0027 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0457 0.0982 0.1228
Schistosoma mansoni nuclear hormone receptor 0.0123 0.0243 0.03
Loa Loa (eye worm) hypothetical protein 0.0473 0.1019 0.1273
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0077 0.1143
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.0124 0.0153
Brugia malayi Nuclear hormone receptor-like 1 0.0334 0.071 0.0887
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0074 0.0135 0.2012
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0029 0.0035 0.0502
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0048 0.0077 0.0072
Loa Loa (eye worm) inositol-1 0.004 0.006 0.0075
Echinococcus granulosus microtubule associated protein 2 0.3673 0.811 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.006 0.1426
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0029 0.0035 0.0029
Schistosoma mansoni single-minded 0.0016 0.0005 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0457 0.0982 0.1228
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0024 0.0019
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0109 0.0212 0.1386
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0109 0.0212 0.0795
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0029 0.0035 0.0063
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0011 0.0063
Entamoeba histolytica hypothetical protein 0.0048 0.0078 0.0319
Leishmania major GTP-binding protein, putative 0.0042 0.0064 0.041
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0029 0.0035 0.0121
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Trypanosoma cruzi hypothetical protein, conserved 0.0236 0.0494 0.3238
Leishmania major glycosyl hydrolase-like protein 0.0015 0.0003 0.0013
Brugia malayi Doublecortin family protein 0.0078 0.0142 0.0178
Plasmodium vivax thioredoxin reductase, putative 0.0315 0.0668 1
Trichomonas vaginalis glutamate synthase, putative 0.0029 0.0035 0.0145
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0457 0.0982 0.1228
Echinococcus granulosus fetal alzheimer antigen falz 0.0034 0.0045 0.0049
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0011 0.0063
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0077 0.0072
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0123 0.0243 0.0293
Echinococcus granulosus lipoxygenase domain containing protein 0.0078 0.0142 0.0169
Echinococcus multilocularis tumor protein p63 0.0665 0.1444 0.1439
Echinococcus granulosus mixed lineage leukemia protein mll 0.002 0.0014 0.001
Echinococcus granulosus cysteine protease atg4b 0.0116 0.0228 0.0274
Entamoeba histolytica hypothetical protein 0.0048 0.0078 0.0319
Schistosoma mansoni hypothetical protein 0.061 0.1321 0.1629
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0008 0.001
Echinococcus multilocularis smad 0.0024 0.0024 0.0019
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0123 0.0243 0.0293
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0029 0.0035 0.022
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0058 0.0374
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0302 0.064 0.08
Mycobacterium tuberculosis Conserved protein 0.0027 0.0031 0.0047
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.005 0.0063
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0045 0.0071 0.1043
Schistosoma mansoni methyl-cpg binding protein mbd 0.0023 0.0021 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0236 0.0494 0.3238
Mycobacterium tuberculosis Probable oxidoreductase 0.0799 0.174 0.7091
Echinococcus granulosus importin subunit beta 1 0.0057 0.0097 0.0113
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0029 0.0035 0.0036
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0008 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.001
Trypanosoma cruzi ISWI complex protein 0.0021 0.0016 0.0097
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0116 0.0228 0.1487
Schistosoma mansoni glutamate synthase 0.0029 0.0035 0.0043
Schistosoma mansoni ran 0.0042 0.0064 0.0078
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0457 0.0982 0.1205
Trypanosoma brucei DNA polymerase IV, putative 0.0025 0.0027 0.0167
Trypanosoma brucei unspecified product 0.0017 0.0009 0.0053
Loa Loa (eye worm) hypothetical protein 0.0051 0.0084 0.0105
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.0365 0.036
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0029 0.0035 0.0051
Echinococcus multilocularis lamin 0.0026 0.0028 0.0023
Mycobacterium ulcerans hypothetical protein 0.0039 0.0057 0.0144
Brugia malayi hypothetical protein 0.0078 0.0142 0.0178
Brugia malayi Latrophilin receptor protein 2 0.015 0.0302 0.0377
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.0031 0.0035
Loa Loa (eye worm) beta-lactamase 0.0039 0.0057 0.0071
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0109 0.0212 0.3164
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Leishmania major hypothetical protein, conserved 0.0029 0.0035 0.022
Echinococcus multilocularis GPCR, family 2 0.015 0.0302 0.0297
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0064 0.0935
Entamoeba histolytica acyl-CoA synthetase, putative 0.0031 0.004 0.0157
Echinococcus granulosus phd:f box containing protein 0.0017 0.0008 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0035
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0074 0.0135 0.6292
Treponema pallidum fructose-bisphosphate aldolase 0.1072 0.2346 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0302 0.064 0.0789
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.012 0.078
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0457 0.0982 0.1225
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0011 0.0063
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0024 0.0023
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0029 0.0035 0.0063
Loa Loa (eye worm) hypothetical protein 0.0039 0.0057 0.0071
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0011 0.0006
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0341 0.0726 0.072
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0029 0.0035 0.022
Plasmodium falciparum LCCL domain-containing protein 0.0078 0.0142 0.2118
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0799 0.174 0.7091
Brugia malayi jmjC domain containing protein 0.0017 0.0008 0.001
Loa Loa (eye worm) TAR-binding protein 0.0411 0.0882 0.1102
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0077 0.0501
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0029 0.0035 0.0051
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0037 0.0051 0.0064
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0008 0.001
Schistosoma mansoni thyroid hormone receptor 0.0457 0.0982 0.1211
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0025 0.0027 0.0033
Echinococcus multilocularis RUN 0.0078 0.0142 0.0137
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0011 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Brugia malayi ecdysteroid receptor 0.3623 0.7999 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0077 0.0072
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0109 0.0212 0.0262
Mycobacterium ulcerans acyl-CoA synthetase 0.0031 0.004 0.0072
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0003 0.001
Trypanosoma brucei polo-like protein kinase 0.0701 0.1524 1
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0035 0.022
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0026 0.0161
Entamoeba histolytica hypothetical protein 0.0048 0.0078 0.0319
Trichomonas vaginalis rotamase, putative 0.0036 0.005 0.0211
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0011 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Onchocerca volvulus 0.0457 0.0982 0.1225
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0077 0.1143
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0334 0.071 0.0875
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.012 0.0114
Loa Loa (eye worm) hypothetical protein 0.0036 0.0051 0.0063
Schistosoma mansoni rotamase 0.0036 0.005 0.0062
Trichomonas vaginalis glutathione reductase, putative 0.0109 0.0212 0.0902
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0152 0.0308 0.0302
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0799 0.174 0.7108
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0457 0.0982 0.0977
Echinococcus multilocularis citrate lyase subunit beta protein 0.0027 0.0031 0.0025
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0135 0.0534
Loa Loa (eye worm) hypothetical protein 0.0078 0.0142 0.0178
Mycobacterium tuberculosis Conserved hypothetical protein 0.0025 0.0027 0.003
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0077 0.0239
Echinococcus granulosus expressed protein 0.0036 0.005 0.0055
Onchocerca volvulus 0.0026 0.0028 0.0031
Loa Loa (eye worm) histone methyltransferase 0.0023 0.0022 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0701 0.1524 0.1879
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0064 0.0072
Brugia malayi hypothetical protein 0.0048 0.0078 0.0097
Echinococcus granulosus Smad4 0.0024 0.0024 0.0023
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0057 0.0155
Loa Loa (eye worm) hypothetical protein 0.0334 0.071 0.0887
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0029 0.0035 0.0043
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0011 0.0013
Schistosoma mansoni terminal deoxycytidyl transferase 0.0025 0.0027 0.0033
Schistosoma mansoni alpha-glucosidase 0.0153 0.031 0.0383
Mycobacterium ulcerans monoxygenase 0.0029 0.0035 0.0051
Toxoplasma gondii NADPH-glutathione reductase 0.0109 0.0212 0.3164
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0073 0.0308
Loa Loa (eye worm) bromodomain containing protein 0.0024 0.0023 0.0028
Trypanosoma brucei DNA polymerase IV, putative 0.0025 0.0027 0.0167
Schistosoma mansoni cellular tumor antigen P53 0.0097 0.0186 0.0229
Brugia malayi nuclear hormone receptor family member odr-7 0.0123 0.0243 0.0304
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0028
Entamoeba histolytica hypothetical protein 0.0048 0.0078 0.0319
Trichomonas vaginalis CAMK family protein kinase 0.0347 0.074 0.3151
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0116 0.0228 0.0968
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.006 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.008 0.0148 0.0185
Toxoplasma gondii endoplasmic reticulum oxidoreductin, putative 0.0051 0.0084 0.1242
Entamoeba histolytica acyl-coA synthetase, putative 0.0031 0.004 0.0157
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0026 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Brugia malayi latrophilin 2 splice variant baaae 0.0323 0.0687 0.0859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0029 0.0035 0.0502
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.012 0.1781
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0005 0.0018
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0001 0.0001
Giardia lamblia Glutamate synthase 0.0029 0.0035 0.0102
Brugia malayi Nuclear hormone receptor-like 1 0.0334 0.071 0.0887
Schistosoma mansoni hypothetical protein 0.015 0.0302 0.0372
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0014 0.001
Schistosoma mansoni zinc finger protein 0.0123 0.0243 0.03
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0011 0.0063
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0029 0.0035 0.0121
Loa Loa (eye worm) hypothetical protein 0.0036 0.0051 0.0063
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0077 0.0501
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0073 0.0472
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.006 0.0253
Brugia malayi Importin beta-1 subunit 0.0057 0.0097 0.0121
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.012 0.0148
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0005 0.0018
Schistosoma mansoni hypothetical protein 0.0078 0.0142 0.0176
Leishmania major trypanothione reductase 0.0315 0.0668 0.438
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0045 0.0071 0.0457
Plasmodium vivax endoplasmic reticulum oxidoreductin, putative 0.0051 0.0084 0.1242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0008 0.0003
Leishmania major DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0035 0.022
Trichomonas vaginalis glutaminase, putative 0.0299 0.0633 0.2696
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0031 0.0194
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0457 0.0982 0.1211
Echinococcus multilocularis cpg binding protein 0.0066 0.0117 0.0112
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0457 0.0982 0.1228
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.001 0.0058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.004 0.0084
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0057 0.007
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0064 0.0226
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0029 0.0035 0.0502
Schistosoma mansoni hypothetical protein 0.015 0.0302 0.0372
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0109 0.0212 0.0265
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1072 0.2346 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0005 0.0018
Brugia malayi beta-lactamase family protein 0.0039 0.0057 0.0071
Echinococcus multilocularis dna polymerase eta 0.0025 0.0027 0.0021
Mycobacterium ulcerans dehydrogenase 0.0029 0.0035 0.0051
Echinococcus multilocularis thyroid hormone receptor alpha 0.0457 0.0982 0.0977
Loa Loa (eye worm) glutathione reductase 0.0315 0.0668 0.0835
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0005 0.0025
Brugia malayi tailless protein 0.0123 0.0243 0.0304
Brugia malayi steroid hormone receptor 0.0457 0.0982 0.1228
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0457 0.0982 0.1205
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0029 0.0035 0.0502
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0123 0.0243 0.0238
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0029 0.0035 0.0135
Giardia lamblia DINP protein human, muc B family 0.0025 0.0027 0.0068
Echinococcus granulosus dna polymerase eta 0.0025 0.0027 0.0026
Brugia malayi TAR-binding protein 0.0411 0.0882 0.1102
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0008 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0457 0.0982 0.1228
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0116 0.0228 0.0281
Loa Loa (eye worm) hypothetical protein 0.0116 0.0228 0.0284
Schistosoma mansoni hypothetical protein 0.0859 0.1874 0.2311
Echinococcus granulosus Nuclear hormone receptor HR96 0.0123 0.0243 0.0293
Loa Loa (eye worm) hypothetical protein 0.0457 0.0982 0.1228
Brugia malayi jmjC domain containing protein 0.0017 0.0008 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0347 0.074 0.3151
Loa Loa (eye worm) hypothetical protein 0.0334 0.071 0.0887
Echinococcus granulosus thioredoxin glutathione reductase 0.0317 0.0673 0.0824
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0029 0.0035 0.0502
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0008 0.001
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0024 0.003
Brugia malayi AMP-binding enzyme family protein 0.0031 0.004 0.005
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0021 0.0016
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0026 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Brugia malayi Calcitonin receptor-like protein seb-1 0.0473 0.1019 0.1273
Trypanosoma brucei hypothetical protein, conserved 0.0236 0.0494 0.3238
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0718 0.1562 0.6358
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0029 0.0035 0.0051
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0718 0.1562 0.6358
Echinococcus granulosus citrate lyase subunit beta protein 0.0027 0.0031 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0011 0.0013
Schistosoma mansoni lamin 0.0026 0.0028 0.0035
Brugia malayi nuclear receptor NHR-88 0.0123 0.0243 0.0304
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Plasmodium falciparum importin beta, putative 0.0057 0.0097 0.1436
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0057 0.0155
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0073 0.0308
Echinococcus granulosus neuropeptide receptor A26 0.1397 0.3067 0.3777
Schistosoma mansoni tar DNA-binding protein 0.0411 0.0882 0.1087
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0028
Loa Loa (eye worm) hypothetical protein 0.0334 0.071 0.0887
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0008 0.0002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0078 0.0142 0.0137
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0457 0.0982 0.0977
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0457 0.0982 0.1211
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0009 0.0053
Loa Loa (eye worm) Smad1 0.0024 0.0024 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0028
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0135 0.0881
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0011 0.0033
Trypanosoma brucei ISWI complex protein 0.0021 0.0016 0.0097
Brugia malayi MH1 domain containing protein 0.0024 0.0024 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0008 0.0002
Schistosoma mansoni transcription factor LCR-F1 0.0048 0.0078 0.0096
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0021 0.0019
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0003 0.001
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0104 0.013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0109 0.0212 0.1386
Schistosoma mansoni DNA polymerase eta 0.0025 0.0027 0.0033
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0058 0.0853
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0029 0.0035 0.0051
Loa Loa (eye worm) hypothetical protein 0.0265 0.0557 0.0696
Giardia lamblia Kinase, PLK 0.0701 0.1524 0.6482
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0027 0.0031 0.0128
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0022 0.0021
Onchocerca volvulus 0.0029 0.0035 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0006
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.001 0.0058
Schistosoma mansoni polycystin 1-related 0.0078 0.0142 0.0176
Plasmodium vivax acyl-CoA synthetase, putative 0.0023 0.0022 0.0317
Loa Loa (eye worm) hypothetical protein 0.0323 0.0687 0.0859
Trypanosoma cruzi endoplasmic reticulum oxidoreductin, putative 0.0051 0.0084 0.0544
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0302 0.064 0.0789
Loa Loa (eye worm) nuclear receptor NHR-67 0.0123 0.0243 0.0304
Brugia malayi RNA, U transporter 1 0.0162 0.033 0.0413
Loa Loa (eye worm) hypothetical protein 0.0026 0.0027 0.0034
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0029 0.0035 0.0121
Onchocerca volvulus Phospholipase A2 homolog 0.0181 0.0372 0.0461
Echinococcus granulosus Peptidase C54 0.0116 0.0228 0.0274
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0035 0.0145
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0027 0.0034
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0116 0.0228 0.1487
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0457 0.0982 0.0977
Leishmania major hypothetical protein, conserved 0.0017 0.0008 0.0044
Echinococcus multilocularis Polycystic kidney disease protein 0.0078 0.0142 0.0137
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.001 0.0058
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0097 0.0091
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.001
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.006 0.0386
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0057 0.0155
Schistosoma mansoni retinoic acid receptor RXR 0.0457 0.0982 0.1211
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0058 0.0245
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0029 0.0035 0.0043
Echinococcus granulosus thyroid hormone receptor alpha 0.0123 0.0243 0.0293
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0048 0.031
Brugia malayi CXXC zinc finger family protein 0.006 0.0104 0.013
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0028 0.0035
Echinococcus granulosus lysosomal alpha glucosidase 0.0178 0.0365 0.0444
Schistosoma mansoni nuclear receptor 0.0123 0.0243 0.03
Loa Loa (eye worm) hypothetical protein 0.0039 0.0057 0.0071
Trypanosoma brucei DNA polymerase IV, putative 0.0025 0.0027 0.0167
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0011 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0005 0.0018
Mycobacterium ulcerans hypothetical protein 0.0027 0.0031 0.0035
Schistosoma mansoni inositol monophosphatase 0.004 0.006 0.0074
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0029 0.0035 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Schistosoma mansoni smad1 5 8 and 0.0024 0.0024 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0457 0.0982 0.1228
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0074 0.0135 0.0467
Trypanosoma brucei NADH dehydrogenase 0.0029 0.0035 0.022
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0008 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0129 0.0257 0.0317
Echinococcus granulosus RUN 0.0078 0.0142 0.0169
Brugia malayi Phospholipase A2 family protein 0.0181 0.0372 0.0465
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.006 0.0155
Loa Loa (eye worm) hypothetical protein 0.0181 0.0372 0.0465
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0029 0.0035 0.0036
Schistosoma mansoni sulfide quinone reductase 0.0029 0.0035 0.0043
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0109 0.0212 0.1386
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0064 0.041
Echinococcus multilocularis lamin dm0 0.0026 0.0028 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1072 0.2346 1
Brugia malayi Thioredoxin reductase 0.0315 0.0668 0.0835
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0074 0.0135 0.2012
Loa Loa (eye worm) glutaminase 0.0299 0.0633 0.0791
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0045 0.0071 0.0457
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0025 0.0027 0.0026
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0048 0.031
Schistosoma mansoni tar DNA-binding protein 0.0411 0.0882 0.1087
Mycobacterium tuberculosis Conserved protein 0.0039 0.0057 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0116 0.0228 0.0968
Mycobacterium ulcerans hypothetical protein 0.0029 0.0035 0.0051
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0029 0.0035 0.0135
Mycobacterium ulcerans ferredoxin reductase 0.0029 0.0035 0.0051
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0064 0.0079
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0109 0.0212 0.0784
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0028 0.0035
Mycobacterium ulcerans glutaminase 0.0299 0.0633 0.252
Loa Loa (eye worm) hypothetical protein 0.3623 0.7999 1
Toxoplasma gondii ABC1 family protein 0.0039 0.0057 0.0839
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0799 0.174 0.7091
Brugia malayi Endoplasmic Reticulum Oxidoreductin 1 0.0051 0.0084 0.0105
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0058 0.0245
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0005 0.0018
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0029 0.0035 0.0145
Brugia malayi Pre-SET motif family protein 0.0129 0.0257 0.0321
Mycobacterium ulcerans hypothetical protein 0.0031 0.004 0.0072
Plasmodium falciparum cysteine protease ATG4, putative 0.0045 0.0071 0.1043
Brugia malayi nuclear receptor RXR 0.0123 0.0243 0.0304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0057 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0058 0.0374
Trichomonas vaginalis rotamase, putative 0.0035 0.0048 0.0203
Mycobacterium ulcerans lipase LipD 0.0039 0.0057 0.0144
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0109 0.0212 0.1386
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0701 0.1524 0.1874
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0457 0.0982 0.1228
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0109 0.0212 0.3164
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0034 0.0045 0.0055
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0024 0.0023
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0003 0.001
Echinococcus multilocularis lipoxygenase domain containing protein 0.0078 0.0142 0.0137
Plasmodium vivax multidomain scavenger receptor, putative 0.0078 0.0142 0.2118
Loa Loa (eye worm) hypothetical protein 0.0457 0.0982 0.1228
Mycobacterium tuberculosis Conserved protein 0.0039 0.0057 0.0155
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0029 0.0035 0.0145
Brugia malayi jmjC domain containing protein 0.0069 0.0124 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0005 0.0018
Entamoeba histolytica peptidase, C54 family 0.0045 0.0071 0.0289
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0011 0.0013
Brugia malayi ImpB/MucB/SamB family protein 0.0025 0.0027 0.0033
Schistosoma mansoni aryl hydrocarbon receptor 0.0016 0.0006 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0701 0.1524 0.6497
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0026 0.0161
Plasmodium vivax JmjC domain containing protein 0.0017 0.0008 0.0101
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0022 0.0317
Echinococcus granulosus Nuclear hormone receptor HR96 0.0123 0.0243 0.0293
Echinococcus granulosus Endoplasmic reticulum oxidoreductin 1 0.0051 0.0084 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0457 0.0982 0.1228
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0077 0.0501
Echinococcus multilocularis L aminoadipate semialdehyde 0.0265 0.0557 0.0552
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0035 0.022
Echinococcus granulosus Polycystic kidney disease protein 0.0078 0.0142 0.0169
Plasmodium vivax glutathione reductase, putative 0.0315 0.0668 1
Brugia malayi nuclear receptor NHR-88 0.0457 0.0982 0.1228
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0074 0.0135 0.0436
Echinococcus granulosus neuropeptide s receptor 0.1397 0.3067 0.3777
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Entamoeba histolytica thioredoxin reductase, putative 0.0029 0.0035 0.0135
Brugia malayi RNA recognition motif domain containing protein 0.0411 0.0882 0.1102
Loa Loa (eye worm) MH2 domain-containing protein 0.0356 0.0759 0.0949
Mycobacterium ulcerans beta-lactamase 0.0039 0.0057 0.0144
Schistosoma mansoni steroid hormone receptor ad4bp 0.0457 0.0982 0.1211
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0052 0.0086 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0457 0.0982 0.1228
Schistosoma mansoni rab6-interacting 0.0078 0.0142 0.0176
Schistosoma mansoni Smad4 0.0024 0.0024 0.003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.0124 0.0153
Schistosoma mansoni zinc finger protein 0.0021 0.0016 0.002
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0031 0.0194
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0302 0.064 0.0635
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1072 0.2346 1
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0029 0.0035 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0009 0.0053
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0037 0.0051 0.0063
Entamoeba histolytica hypothetical protein 0.0025 0.0026 0.0097
Leishmania major hypothetical protein, conserved 0.0021 0.0016 0.0097
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.015 0.0302 0.0297
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0035 0.0145
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0718 0.1562 0.6358
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0302 0.064 0.0783
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0024 0.003
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0265 0.0557 0.0696
Brugia malayi Inositol-1 0.004 0.006 0.0075
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0014 0.0009
Echinococcus granulosus tar DNA binding protein 0.0411 0.0882 0.1081
Brugia malayi photoreceptor-specific nuclear receptor 0.0457 0.0982 0.1228
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0116 0.0228 0.0281
Echinococcus multilocularis snurportin 1 0.061 0.1321 0.1316
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0109 0.0212 0.0784
Echinococcus granulosus GPCR family 2 0.015 0.0302 0.0366
Onchocerca volvulus 0.0265 0.0557 0.0693
Entamoeba histolytica deoxycytidyl transferase, putative 0.0025 0.0027 0.0101
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0129 0.0257 0.3835
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0334 0.071 0.0875
Echinococcus granulosus FTZ F1 alpha 0.0457 0.0982 0.1205
Trypanosoma cruzi NADH dehydrogenase, putative 0.0029 0.0035 0.022
Schistosoma mansoni coup transcription factor 0.0457 0.0982 0.1211
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0058 0.0245
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0109 0.0212 1
Schistosoma mansoni disulfide oxidoreductase 0.0029 0.0035 0.0043
Onchocerca volvulus 0.1017 0.2224 0.2778
Entamoeba histolytica hypothetical protein 0.0074 0.0135 0.0565
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0097 0.1436
Chlamydia trachomatis thioredoxin reductase 0.0029 0.0035 0.143
Loa Loa (eye worm) programmed cell death 8 0.0029 0.0035 0.0043
Trichomonas vaginalis esterase, putative 0.0039 0.0057 0.0241
Brugia malayi hypothetical protein 0.0153 0.031 0.0387
Echinococcus granulosus histone lysine methyltransferase setb 0.0152 0.0308 0.0373
Schistosoma mansoni hypothetical protein 0.0323 0.0687 0.0847
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0029 0.0035 0.022
Schistosoma mansoni nuclear receptor 0.0123 0.0243 0.03
Onchocerca volvulus 0.0123 0.0243 0.03
Echinococcus granulosus ecdysone induced protein 78C 0.0457 0.0982 0.1205
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0048 0.0707
Schistosoma mansoni ero1-related 0.0051 0.0084 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1072 0.2346 1
Plasmodium vivax ferrodoxin reductase, putative 0.0029 0.0035 0.0502
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0029 0.0035 0.0036
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0031 0.004 0.0072
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0029 0.0035 0.0502
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0039 0.0057 0.0071
Schistosoma mansoni glutamate synthase 0.0029 0.0035 0.0043
Leishmania major NADH dehydrogenase, putative 0.0029 0.0035 0.022
Brugia malayi jmjC domain containing protein 0.0017 0.0008 0.001
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.012 0.0148
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0057 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0064 0.0935
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0029 0.0035 0.0029
Echinococcus granulosus lamin dm0 0.0026 0.0028 0.0028
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0024 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0457 0.0982 0.1228
Onchocerca volvulus 0.0129 0.0257 0.0318
Schistosoma mansoni smad 0.0024 0.0024 0.003
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0457 0.0982 0.1228
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0048 0.0078 0.0072
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0011 0.0063
Schistosoma mansoni bromodomain containing protein 0.0088 0.0166 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0029 0.0035 0.0036
Echinococcus multilocularis aryl hydrocarbon receptor 0.0052 0.0086 0.0081
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0022 0.0017
Onchocerca volvulus 0.0123 0.0243 0.03
Echinococcus multilocularis microtubule associated protein 2 0.3673 0.811 0.8109
Mycobacterium tuberculosis Conserved protein 0.0039 0.0057 0.0155
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.008 0.0148 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0457 0.0982 0.1228
Trichomonas vaginalis mercuric reductase, putative 0.0109 0.0212 0.0902
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0018 0.0111
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0701 0.1524 0.152
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0109 0.0212 0.1386
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0011 0.0063
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0005 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.012 0.0403
Schistosoma mansoni intermediate filament proteins 0.0026 0.0028 0.0035
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0029 0.0035 0.0063
Schistosoma mansoni zinc finger protein 0.003 0.0036 0.0045
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0074 0.0135 0.0467
Trichomonas vaginalis DNA polymerase eta, putative 0.0025 0.0027 0.0111
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0457 0.0982 0.1228
Echinococcus multilocularis expressed protein 0.0036 0.005 0.0045
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0457 0.0982 0.1205
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.004 0.0143
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0029 0.0035 0.0135
Trypanosoma cruzi ISWI complex protein 0.0021 0.0016 0.0097
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0077 0.0089
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0057 0.0155
Trypanosoma cruzi polo-like protein kinase, putative 0.0701 0.1524 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0011 0.0063
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0011 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0009 0.0053
Trypanosoma brucei unspecified product 0.0017 0.0009 0.0053
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0074 0.0135 0.5673
Trypanosoma cruzi trypanothione reductase, putative 0.0109 0.0212 0.1386
Brugia malayi jmjC domain containing protein 0.0063 0.0111 0.0138
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0083 0.0155 0.015
Leishmania major importin beta-1 subunit, putative 0.0046 0.0073 0.0472
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0457 0.0982 0.1228
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0302 0.064 0.0789
Echinococcus multilocularis dna polymerase kappa 0.0025 0.0027 0.0021
Loa Loa (eye worm) hypothetical protein 0.0055 0.0091 0.0114
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0008 0.0044
Onchocerca volvulus 0.0039 0.0057 0.0068
Mycobacterium tuberculosis Probable reductase 0.0718 0.1562 0.6358
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0109 0.0212 0.3164
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0701 0.1524 0.1905
Mycobacterium ulcerans NADH dehydrogenase 0.0029 0.0035 0.0051
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0109 0.0212 0.3164
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0057 0.0155
Schistosoma mansoni hypothetical protein 0.0028 0.0032 0.0039
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.1117 0.2446 1
Brugia malayi intermediate filament protein 0.0026 0.0028 0.0035
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0064 0.0079
Trypanosoma cruzi NADH dehydrogenase, putative 0.0029 0.0035 0.022
Onchocerca volvulus 0.0026 0.0028 0.0031
Loa Loa (eye worm) hypothetical protein 0.0095 0.018 0.0225
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0058 0.0245
Loa Loa (eye worm) hypothetical protein 0.0029 0.0035 0.0043
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0029 0.0035 0.0029
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0035 0.0145
Schistosoma mansoni rab6-interacting 0.0078 0.0142 0.0176
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0029 0.0035 0.0051
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0031 0.004 0.0072
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0077 0.0072
Loa Loa (eye worm) hypothetical protein 0.0036 0.0051 0.0063
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0035 0.0145
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1072 0.2346 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0048 0.031
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0004
Trichomonas vaginalis adenylate cyclase, putative 0.0016 0.0005 0.0018
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0077 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0457 0.0982 0.1228
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0011 0.0063
Schistosoma mansoni cpg binding protein 0.006 0.0104 0.0128
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0109 0.0212 0.1386
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.004 0.0143
Brugia malayi glutathione reductase 0.0315 0.0668 0.0835
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0457 0.0982 0.1205
Brugia malayi RNA binding protein 0.0411 0.0882 0.1102
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0077 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0026 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0701 0.1524 0.6497
Loa Loa (eye worm) hypothetical protein 0.0153 0.031 0.0387
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0109 0.0212 0.0255
Schistosoma mansoni sulfide quinone reductase 0.0029 0.0035 0.0043
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0111 0.0137
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0026 0.0369
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.006 0.0243
Trypanosoma cruzi DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Loa Loa (eye worm) hypothetical protein 0.0334 0.071 0.0887
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0057 0.0368
Loa Loa (eye worm) hypothetical protein 0.0051 0.0084 0.0105
Entamoeba histolytica disulphide oxidoreductase, putative 0.0029 0.0035 0.0135
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0123 0.0243 0.0304
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0003 0.0013
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0109 0.0212 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0031 0.004 0.0072
Echinococcus multilocularis Peptidase C54 0.0116 0.0228 0.0222
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0109 0.0212 0.1386
Echinococcus granulosus dnaJ subfamily B 0.0859 0.1874 0.2306
Loa Loa (eye worm) hypothetical protein 0.0123 0.0243 0.0304
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0123 0.0243 0.03
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.005 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0457 0.0982 0.1228
Leishmania major 4-coumarate:coa ligase-like protein 0.0031 0.004 0.0254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0011 0.0043
Leishmania major hypothetical protein, conserved 0.0029 0.0035 0.022
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0026 0.002
Schistosoma mansoni hypothetical protein 0.015 0.0302 0.0372
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0064 0.0058
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0109 0.0212 0.1386
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0077 0.0072
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.001 0.0058
Echinococcus multilocularis cysteine protease atg4b 0.0116 0.0228 0.0222
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0045 0.0071 0.0457
Schistosoma mansoni hypothetical protein 0.1139 0.2495 0.3076
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0011 0.0063
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0057 0.0071
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0024 0.0019
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.1117 0.2446 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0027 0.0167
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.006 0.0386
Brugia malayi beta-lactamase family protein 0.0039 0.0057 0.0071
Brugia malayi MH2 domain containing protein 0.0024 0.0024 0.003
Onchocerca volvulus 0.0153 0.031 0.0384
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0033
Echinococcus granulosus tumor protein p63 0.0665 0.1444 0.1775
Brugia malayi hypothetical protein 0.0014 0.0001 0.0001
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0011 0.0006
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0058 0.0072

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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