Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0039 | 0.531 | 1 |
Echinococcus granulosus | calcium activated potassium channel variant | 0.0043 | 0.7916 | 0.5556 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.531 | 0.5 |
Echinococcus multilocularis | calcium activated potassium channel variant | 0.0043 | 0.7916 | 0.5556 |
Loa Loa (eye worm) | large conductance calcium-activated potassium channel alpha subunit ai | 0.0043 | 0.7916 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.531 | 0.5 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0043 | 0.7916 | 0.5556 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.531 | 0.5 |
Echinococcus multilocularis | calcium activated potassium channel | 0.0046 | 1 | 1 |
Echinococcus multilocularis | potassium large conductance calcium activated | 0.0046 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.531 | 0.5 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0046 | 1 | 1 |
Echinococcus granulosus | potassium large conductance calcium activated | 0.0046 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.