Detailed information for compound 573094

Basic information

Technical information
  • TDR Targets ID: 573094
  • Name: 3-[2-(3,4-dimethoxyphenyl)ethylamino]-1-(4-io dophenyl)pyrrolidine-2,5-dione
  • MW: 480.296 | Formula: C20H21IN2O4
  • H donors: 1 H acceptors: 2 LogP: 2.95 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(CCNC2CC(=O)N(C2=O)c2ccc(cc2)I)ccc1OC
  • InChi: 1S/C20H21IN2O4/c1-26-17-8-3-13(11-18(17)27-2)9-10-22-16-12-19(24)23(20(16)25)15-6-4-14(21)5-7-15/h3-8,11,16,22H,9-10,12H2,1-2H3
  • InChiKey: NYZPQOYZNIRKCK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-(homoveratrylamino)-1-(4-iodophenyl)pyrrolidine-2,5-quinone
  • diphenic anhydride
  • 3-[2-(3,4-dimethoxyphenyl)ethylamino]-1-(4-iodophenyl)pyrrolidine-2,5-quinone
  • CBMicro_042837
  • STK327666
  • BIM-0042740.P001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0108 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0101 0.0246
Loa Loa (eye worm) hypothetical protein 0.0186 0.0906 0.0906
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0192 0.094 0.0916
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0108 0.0107
Schistosoma mansoni carbonic anhydrase-related 0.0216 0.1075 0.1074
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0076 0.0299 0.089
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0206 0.0206
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0076 0.0299 0.0299
Brugia malayi jmjC domain containing protein 0.006 0.0212 0.021
Trypanosoma brucei trypanothione reductase 0.0076 0.0299 0.0888
Loa Loa (eye worm) hypothetical protein 0.0041 0.0108 0.0108
Loa Loa (eye worm) glutathione reductase 0.0076 0.0299 0.0299
Loa Loa (eye worm) hypothetical protein 0.0041 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0041 0.0108 0.0108
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0199 0.0981 0.0981
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0583 0.3097 0.3097
Echinococcus granulosus lysosomal alpha glucosidase 0.018 0.0874 0.0874
Echinococcus granulosus carbonic anhydrase 0.0216 0.1075 0.1075
Mycobacterium tuberculosis Probable oxidoreductase 0.0192 0.094 0.0916
Loa Loa (eye worm) hypothetical protein 0.0041 0.0108 0.0108
Mycobacterium tuberculosis Probable dehydrogenase 0.0173 0.0833 0.081
Schistosoma mansoni cpg binding protein 0.0062 0.0224 0.0223
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0583 0.3097 1
Plasmodium vivax SET domain protein, putative 0.0091 0.0385 0.4087
Onchocerca volvulus 0.0186 0.0906 0.0806
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.1523 0.3933
Trichomonas vaginalis importin beta-1, putative 0.0051 0.0162 0.0356
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0813 0.4366 0.4366
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0108 0.0107
Trypanosoma brucei carbonic anhydrase-like protein 0.0583 0.3097 1
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0583 0.3097 0.3096
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0212 0.0212
Toxoplasma gondii exonuclease III APE 0.0057 0.0198 0.1644
Onchocerca volvulus 0.0048 0.0146 0.0038
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0299 0.089
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Echinococcus multilocularis GPCR, family 2 0.0033 0.0065 0.0065
Echinococcus multilocularis importin subunit beta 1 0.0063 0.0227 0.0227
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0195 0.0957 0.0957
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0198 0.0453
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0076 0.0299 0.0273
Treponema pallidum glutamate transporter 0.0813 0.4366 1
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0076 0.0299 0.0298
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0198 0.0173
Chlamydia trachomatis glutamate symporter 0.1834 1 1
Echinococcus granulosus tumor protein p63 0.0328 0.1688 0.1688
Trichomonas vaginalis set domain proteins, putative 0.0716 0.3833 1
Schistosoma mansoni hypothetical protein 0.0041 0.0107 0.0106
Loa Loa (eye worm) hypothetical protein 0.0091 0.0385 0.0385
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0428 0.2445
Mycobacterium tuberculosis Probable reductase 0.0173 0.0833 0.081
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0186 0.0906 0.0882
Giardia lamblia Fructose-bisphosphate aldolase 0.0298 0.1523 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0212 0.0212
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0108 0.0108
Brugia malayi hypothetical protein 0.0241 0.121 0.1209
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0198 0.0562
Schistosoma mansoni aldehyde dehydrogenase 0.0199 0.0981 0.098
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.1523 0.3933
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0216 0.1075 0.1075
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.0906 0.2311
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0428 0.0428
Brugia malayi follicle stimulating hormone receptor 0.0483 0.2544 0.2543
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0108 0.0108
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0186 0.0906 0.0904
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0299 0.0718
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0116 0.0116
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0108 0.0108
Loa Loa (eye worm) carbonic anhydrase 3 0.0583 0.3097 0.3097
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0116 0.0236
Loa Loa (eye worm) hypothetical protein 0.0216 0.1075 0.1075
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0001 0.0001
Echinococcus granulosus neuropeptide s receptor 0.0474 0.2497 0.2497
Schistosoma mansoni aldehyde dehydrogenase 0.0199 0.0981 0.098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0957 0.0956
Echinococcus multilocularis excitatory amino acid transporter 2 0.1834 1 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0046 0.0136 0.1248
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0108 0.0108
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0046 0.0136 0.1046
Brugia malayi RNA, U transporter 1 0.0178 0.0864 0.0863
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1642 0.8938 0.8938
Schistosoma mansoni importin beta-1 0.0063 0.0227 0.0226
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0158 0.1256
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Brugia malayi nuclear receptor NHR-88 0.0041 0.0108 0.0107
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0957 0.0957
Brugia malayi Importin beta-1 subunit 0.0063 0.0227 0.0226
Mycobacterium tuberculosis Conserved protein 0.0186 0.0906 0.0882
Loa Loa (eye worm) hypothetical protein 0.0041 0.0108 0.0108
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.0906 0.2865
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0669 0.3571 0.3571
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0198 0.0198
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0957 0.0956
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0046 0.0136 0.0733
Loa Loa (eye worm) transcription factor SMAD2 0.0132 0.0608 0.0608
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0108 0.0108
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0046 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0336 0.1732 0.1732
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0108 0.0107
Echinococcus multilocularis lysosomal alpha glucosidase 0.018 0.0874 0.0874
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0299 0.0718
Echinococcus granulosus thioredoxin glutathione reductase 0.0077 0.0304 0.0304
Onchocerca volvulus 0.0716 0.3833 0.3765
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0279 0.0277
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0065 0.0065
Onchocerca volvulus 0.0186 0.0906 0.0806
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.0906 0.2311
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.0186 0.0906 0.0906
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0195 0.0957 0.0956
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0108 0.0107
Schistosoma mansoni ap endonuclease 0.0057 0.0198 0.0197
Toxoplasma gondii thioredoxin reductase 0.0076 0.0299 0.2599
Loa Loa (eye worm) hypothetical protein 0.0072 0.0279 0.0279
Mycobacterium leprae Probable lipase LipE 0.0186 0.0906 0.8675
Schistosoma mansoni carbonic anhydrase-related 0.0216 0.1075 0.1074
Toxoplasma gondii ABC1 family protein 0.0186 0.0906 0.8384
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0105 0.0462 0.0461
Loa Loa (eye worm) hypothetical protein 0.0041 0.0108 0.0108
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0108 0.0108
Echinococcus granulosus carbonic anhydrase 0.0216 0.1075 0.1075
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.023 0.023
Trypanosoma brucei importin beta-1 subunit, putative 0.0063 0.0227 0.0655
Echinococcus multilocularis neutral amino acid transporter A 0.1834 1 1
Mycobacterium ulcerans esterase/lipase LipP 0.0186 0.0906 0.9208
Loa Loa (eye worm) hypothetical protein 0.0186 0.0906 0.0906
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0199 0.0981 0.0958
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0957 0.0956
Toxoplasma gondii aldehyde dehydrogenase 0.0199 0.0981 0.9106
Schistosoma mansoni hypothetical protein 0.0049 0.0152 0.0151
Echinococcus multilocularis beta LACTamase domain containing family member 0.0186 0.0906 0.0906
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0198 0.0453
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0001 0.0001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0065 0.0064
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0076 0.0299 0.0299
Echinococcus granulosus cpg binding protein 0.0062 0.0224 0.0224
Brugia malayi beta-lactamase 0.0186 0.0906 0.0904
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0428 0.0428
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0108 0.0107
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0108 0.0108
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0076 0.0299 0.1559
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0198 0.1961
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0101 0.0198
Plasmodium vivax hypothetical protein, conserved 0.0186 0.0906 1
Schistosoma mansoni hypothetical protein 0.0041 0.0107 0.0106
Echinococcus multilocularis cpg binding protein 0.0062 0.0224 0.0224
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0108 0.0108
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0813 0.4366 0.4366
Brugia malayi glutathione reductase 0.0076 0.0299 0.0297
Echinococcus multilocularis geminin 0.0343 0.1775 0.1775
Echinococcus granulosus Excitatory amino acid transporter 0.1834 1 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0198 0.0562
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.1523 0.3933
Echinococcus granulosus ubiquitin specific protease 41 0.0076 0.0299 0.0299
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0108 0.0108
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0101 0.072
Entamoeba histolytica hypothetical protein 0.0051 0.0162 0.0609
Trichomonas vaginalis esterase, putative 0.0186 0.0906 0.2311
Loa Loa (eye worm) hypothetical protein 0.0216 0.1075 0.1075
Brugia malayi Thioredoxin reductase 0.0076 0.0299 0.0297
Brugia malayi Calcitonin receptor-like protein seb-1 0.0105 0.0462 0.0461
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.063 0.3354 0.3354
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0108 0.0107
Echinococcus granulosus importin subunit beta 1 0.0063 0.0227 0.0227
Schistosoma mansoni alpha glucosidase 0.004 0.0101 0.01
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0108 0.0108
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0108 0.0108
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.1523 0.3933
Schistosoma mansoni hypothetical protein 0.0041 0.0107 0.0106
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0108 0.0108
Onchocerca volvulus 0.0059 0.0206 0.0098
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0108 0.0107
Plasmodium vivax thioredoxin reductase, putative 0.0076 0.0299 0.31
Echinococcus multilocularis microtubule associated protein 2 0.0729 0.3903 0.3903
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0108 0.0108
Echinococcus granulosus snurportin 1 0.0669 0.3571 0.3571
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0957 0.0957
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0186 0.0906 0.0906
Schistosoma mansoni hypothetical protein 0.0022 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0099 0.0428 0.0428
Schistosoma mansoni hypothetical protein 0.0343 0.1775 0.1774
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0108 0.0107
Toxoplasma gondii hypothetical protein 0.0216 0.1075 1
Mycobacterium ulcerans hypothetical protein 0.0186 0.0906 0.9208
Schistosoma mansoni ran 0.0046 0.0136 0.0134
Schistosoma mansoni patched 1 0.0043 0.0116 0.0115
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0065 0.0065
Echinococcus multilocularis lysosomal alpha glucosidase 0.018 0.0874 0.0874
Brugia malayi steroid hormone receptor 0.0041 0.0108 0.0107
Brugia malayi CXXC zinc finger family protein 0.0059 0.0206 0.0205
Loa Loa (eye worm) hypothetical protein 0.0186 0.0906 0.0906
Mycobacterium tuberculosis Conserved protein 0.0186 0.0906 0.0882
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0101 0.0246
Echinococcus multilocularis expressed conserved protein 0.0093 0.0395 0.0395
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0108 0.0108
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0101 0.0194
Schistosoma mansoni hypothetical protein 0.0343 0.1775 0.1774
Loa Loa (eye worm) hypothetical protein 0.0186 0.0906 0.0906
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0216 0.1075 0.1074
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0583 0.3097 0.3096
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0385 0.0384
Brugia malayi CHE-14 protein 0.0043 0.0116 0.0115
Onchocerca volvulus 0.0186 0.0906 0.0806
Echinococcus granulosus sodium:dicarboxylate symporter 0.1834 1 1
Echinococcus multilocularis Excitatory amino acid transporter 0.1834 1 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0136 0.0357
Loa Loa (eye worm) hypothetical protein 0.0043 0.0116 0.0116
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0101 0.0198
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0076 0.0299 0.0299
Echinococcus multilocularis protein dispatched 1 0.0049 0.0149 0.0149
Leishmania major hypothetical protein, conserved 0.005 0.0158 0.0429
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0108 0.0107
Brugia malayi beta-lactamase family protein 0.0186 0.0906 0.0904
Schistosoma mansoni hypothetical protein 0.0033 0.0065 0.0064
Trypanosoma cruzi trypanothione reductase, putative 0.0076 0.0299 0.0888
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0813 0.4366 0.4366
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0299 0.089
Schistosoma mansoni hypothetical protein 0.0216 0.1075 0.1074
Schistosoma mansoni hypothetical protein 0.0669 0.3571 0.357
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0076 0.0299 0.0299
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0005 0.0005
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0186 0.0906 0.0882
Echinococcus granulosus beta LACTamase domain containing family member 0.0186 0.0906 0.0906
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0198 0.0562
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0101 0.0194
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.023 0.0229
Trichomonas vaginalis ran, putative 0.0046 0.0136 0.0288
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0173 0.0833 0.081
Trypanosoma brucei hypothetical protein, conserved 0.0186 0.0906 0.2865
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.0105 0.0462 0.0462
Schistosoma mansoni hypothetical protein 0.0035 0.0073 0.0072
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0105 0.0462 0.0462
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0186 0.0906 0.0882
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0046 0.0136 0.0357
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0108 0.0107
Mycobacterium ulcerans lipase LipD 0.0186 0.0906 0.9208
Echinococcus granulosus Excitatory amino acid transporter 0.1834 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0108 0.0108
Echinococcus granulosus carbonic anhydrase 0.0216 0.1075 0.1075
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0001 0.0001
Schistosoma mansoni alpha-glucosidase 0.0155 0.0735 0.0734
Mycobacterium ulcerans aldehyde dehydrogenase 0.0199 0.0981 1
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.121 0.121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0108 0.0108
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0216 0.1075 0.1074
Plasmodium falciparum importin beta, putative 0.0063 0.0227 0.1916
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.0906 0.2311
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0108 0.0107
Trypanosoma brucei glucosidase, putative 0.004 0.0101 0.0246
Echinococcus multilocularis carbonic anhydrase 0.0216 0.1075 0.1075
Echinococcus multilocularis carbonic anhydrase 0.0216 0.1075 0.1075
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0101 0.0101
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0428 0.0427
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0198 0.1644
Loa Loa (eye worm) hypothetical protein 0.0241 0.121 0.121
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.0026 0.0026
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0186 0.0906 0.9208
Schistosoma mansoni cpg binding protein 0.0062 0.0224 0.0223
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.0588 0.0587
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0108 0.0108
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0052 0.0169 0.0169
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0136 0.0357
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0957 0.0957
Loa Loa (eye worm) thioredoxin reductase 0.0076 0.0299 0.0299
Echinococcus granulosus neutral amino acid transporter A 0.1834 1 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0198 0.0198
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0515 0.4658
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0162 0.0356
Echinococcus multilocularis thioredoxin glutathione reductase 0.0077 0.0304 0.0304
Loa Loa (eye worm) beta-lactamase 0.0186 0.0906 0.0906
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0108 0.0107
Echinococcus multilocularis neuropeptide s receptor 0.0474 0.2497 0.2497
Schistosoma mansoni coup transcription factor 0.0041 0.0108 0.0107
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0116 0.0116
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0158 0.1256
Brugia malayi MH2 domain containing protein 0.0132 0.0608 0.0607
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0073 0.0072
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0108 0.0108
Echinococcus granulosus excitatory amino acid transporter 2 0.1834 1 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0132 0.0608 0.0608
Schistosoma mansoni cpg binding protein 0.0059 0.0206 0.0205
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0108 0.0107
Echinococcus multilocularis Niemann Pick C1 protein 0.0142 0.0662 0.0662
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0101 0.0198
Brugia malayi hypothetical protein 0.0035 0.0073 0.0072
Brugia malayi hypothetical protein 0.0032 0.006 0.0058
Echinococcus multilocularis carbonic anhydrase 0.0216 0.1075 0.1075
Echinococcus multilocularis muscleblind protein 0.0336 0.1732 0.1732
Brugia malayi ecdysteroid receptor 0.0041 0.0108 0.0107
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0216 0.1075 0.1075
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0108 0.0107
Echinococcus multilocularis neutral amino acid transporter A 0.1834 1 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0299 0.0299
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0212 0.0212
Echinococcus granulosus dnaJ subfamily B 0.0838 0.4505 0.4505
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0162 0.0356
Mycobacterium tuberculosis Probable hydrolase 0.0186 0.0906 0.0882
Mycobacterium tuberculosis Probable esterase LipL 0.0186 0.0906 0.0882
Schistosoma mansoni hypothetical protein 0.0033 0.0065 0.0064
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0046 0.0136 0.0136
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0385 0.3427
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0198 0.0397
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0091 0.0385 0.0384
Echinococcus granulosus geminin 0.0343 0.1775 0.1775
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0046 0.0136 0.0134
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0385 0.0384
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0101 0.0198
Trypanosoma cruzi importin beta-1 subunit, putative 0.0051 0.0162 0.0442
Chlamydia trachomatis neutral amino acid transporter 0.0813 0.4366 0.4352
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.018 0.0874 0.0874
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0583 0.3097 0.3096
Mycobacterium leprae conserved hypothetical protein 0.0186 0.0906 0.8675
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0186 0.0906 0.0904
Brugia malayi nuclear hormone receptor 0.0041 0.0108 0.0107
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.0385 0.0385
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.0026 0.0025
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0198 0.1152
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0108 0.0108
Echinococcus granulosus expressed conserved protein 0.0093 0.0395 0.0395
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.0385 0.0385
Echinococcus granulosus GTP binding nuclear protein Ran 0.0046 0.0136 0.0136
Toxoplasma gondii HEAT repeat-containing protein 0.0063 0.0227 0.1916
Treponema pallidum fructose-bisphosphate aldolase 0.0298 0.1523 0.345
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.1834 1 1
Leishmania major GTP-binding protein, putative 0.0046 0.0136 0.0357
Schistosoma mansoni alpha-glucosidase 0.0155 0.0735 0.0734
Echinococcus granulosus GPCR family 2 0.0033 0.0065 0.0065
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0108 0.0107
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0108 0.0108
Schistosoma mansoni microtubule-associated protein tau 0.0729 0.3903 0.3903
Echinococcus granulosus neuropeptide receptor A26 0.0474 0.2497 0.2497
Schistosoma mansoni hypothetical protein 0.0072 0.0279 0.0277
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.1834 1 1
Leishmania major hypothetical protein, conserved 0.0186 0.0906 0.2865
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0199 0.0981 0.3111
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0158 0.0429
Mycobacterium ulcerans aldehyde dehydrogenase 0.0199 0.0981 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0199 0.0981 0.0981
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.0026 0.0025
Echinococcus multilocularis carbonic anhydrase II 0.0583 0.3097 0.3097
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0065 0.0065
Echinococcus multilocularis neutral amino acid transporter A 0.1834 1 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0227 0.0227
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0116 0.0116
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0101 0.0436 0.0435
Echinococcus granulosus neutral amino acid transporter A 0.1834 1 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.036 0.036
Trypanosoma brucei importin beta-1 subunit, putative 0.0063 0.0227 0.0655
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.1523 0.3933
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0192 0.094 1
Echinococcus multilocularis muscleblind protein 1 0.0336 0.1732 0.1732
Echinococcus granulosus excitatory amino acid transporter 3 0.1834 1 1
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0046 0.0136 0.1046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0108 0.0107
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0152 0.0151
Echinococcus granulosus carbonic anhydrase II 0.0583 0.3097 0.3097
Schistosoma mansoni hypothetical protein 0.0033 0.0065 0.0064
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0583 0.3097 1
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0158 0.0429
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0005 0.0005
Leishmania major trypanothione reductase 0.0076 0.0299 0.0888
Onchocerca volvulus Excitatory amino acid transporter homolog 0.1834 1 1
Schistosoma mansoni carbonic anhydrase-related 0.0216 0.1075 0.1074
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.023 0.0229
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.1523 0.3933
Mycobacterium ulcerans beta-lactamase 0.0186 0.0906 0.9208
Onchocerca volvulus 0.0091 0.0385 0.028
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.0906 0.2865
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0065 0.0064
Schistosoma mansoni hypothetical protein 0.0838 0.4505 0.4504
Echinococcus granulosus neutral amino acid transporter 0.1834 1 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0101 0.0198
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0385 0.0384
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0198 0.0173
Mycobacterium tuberculosis Conserved protein 0.0186 0.0906 0.0882
Schistosoma mansoni carbonic anhydrase 0.0216 0.1075 0.1074
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0108 0.0107
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0065 0.0065
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0145 0.0683 0.6881
Echinococcus multilocularis excitatory amino acid transporter 3 0.1834 1 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0108 0.0107
Mycobacterium tuberculosis Probable lipase LipD 0.0186 0.0906 0.0882
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0158 0.0429
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0145 0.0683 0.0659
Brugia malayi Pre-SET motif family protein 0.063 0.3354 0.3353
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0483 0.2544 0.2544
Loa Loa (eye worm) hypothetical protein 0.0336 0.1732 0.1732
Entamoeba histolytica Ran family GTPase 0.0046 0.0136 0.043
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0173 0.0833 0.081
Leishmania major carbonic anhydrase-like protein 0.0583 0.3097 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0199 0.0981 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0173 0.0833 0.5854
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0192 0.094 0.0916
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0173 0.0833 0.081
Brugia malayi Pre-SET motif family protein 0.0091 0.0385 0.0384
Plasmodium vivax glutathione reductase, putative 0.0076 0.0299 0.31
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0108 0.0107
Echinococcus granulosus excitatory amino acid transporter 2 0.1834 1 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0299 0.089
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0108 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0108 0.0107
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.1523 0.3933
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0033 0.0065 0.0065
Brugia malayi jmjC domain containing protein 0.0063 0.023 0.0229
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0173 0.0833 0.081
Echinococcus multilocularis dnaJ subfamily B 0.0838 0.4505 0.4505
Echinococcus multilocularis snurportin 1 0.0669 0.3571 0.3571
Plasmodium falciparum carbonic anhydrase 0.0216 0.1075 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0158 0.0158
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0101 0.0198
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0108 0.0108
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1186 0.6426 0.6417
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0073 0.0073
Schistosoma mansoni hypothetical protein 0.0041 0.0107 0.0106
Plasmodium falciparum thioredoxin reductase 0.0076 0.0299 0.2599
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0076 0.0299 0.0298
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0158 0.1498
Echinococcus granulosus muscleblind protein 0.0336 0.1732 0.1732
Brugia malayi Muscleblind-like protein 0.0336 0.1732 0.1731
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0108 0.0107
Schistosoma mansoni survival motor neuron protein 0.0049 0.0152 0.0151
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.121 0.121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.1523 0.3933
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0146 0.0144
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0108 0.0108
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.1834 1 1
Mycobacterium tuberculosis Probable lipase LipE 0.0186 0.0906 0.0882
Trichomonas vaginalis penicillin-binding protein, putative 0.0186 0.0906 0.2311
Plasmodium vivax importin-beta 2, putative 0.0063 0.0227 0.2285
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0216 0.1075 0.1074
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0076 0.0299 0.1826
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0116 0.0116
Schistosoma mansoni ap endonuclease 0.0057 0.0198 0.0197
Echinococcus multilocularis ubiquitin specific protease 41 0.0076 0.0299 0.0299
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0186 0.0906 0.0904
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0216 0.1075 0.1074
Echinococcus multilocularis Excitatory amino acid transporter 0.1834 1 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.018 0.0874 0.0872
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0957 0.0957
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0108 0.0107
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0198 0.0562
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0216 0.1075 0.1074
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.1523 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0101 0.01
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0198 0.0198
Trichomonas vaginalis penicillin-binding protein, putative 0.0186 0.0906 0.2311
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0108 0.0108
Schistosoma mansoni ran 0.0046 0.0136 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0108 0.0108
Echinococcus multilocularis neuropeptide receptor A26 0.0474 0.2497 0.2497
Plasmodium falciparum glutathione reductase 0.0076 0.0299 0.2599
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0108 0.0107
Echinococcus multilocularis excitatory amino acid transporter 2 0.1834 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0101 0.0198
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0198 0.0197
Schistosoma mansoni hypothetical protein 0.0033 0.0065 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0299 0.0718
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0065 0.0065
Onchocerca volvulus 0.0049 0.0152 0.0044
Loa Loa (eye worm) hypothetical protein 0.0041 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0048 0.0146 0.0146
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0101 0.0198
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0198 0.1805
Schistosoma mansoni jumonji domain containing protein 0.006 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.0041 0.0108 0.0108
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0101 0.0246
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0101 0.0198
Brugia malayi hypothetical protein 0.005 0.0158 0.0156
Echinococcus granulosus microtubule associated protein 2 0.0729 0.3903 0.3903
Leishmania major importin beta-1 subunit, putative 0.0051 0.0162 0.0442
Loa Loa (eye worm) hypothetical protein 0.0186 0.0906 0.0906
Echinococcus granulosus Niemann Pick C1 protein 0.0142 0.0662 0.0662
Treponema pallidum glutamate/aspartate transporter 0.0813 0.4366 1
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0158 0.1256
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0101 0.0101
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.1834 1 1
Echinococcus multilocularis protein patched 0.0043 0.0116 0.0116
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0076 0.0299 0.0298
Onchocerca volvulus 0.0104 0.0455 0.035
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.023 0.023
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0073 0.0073
Loa Loa (eye worm) excitatory amino acid transporter 0.1834 1 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0385 0.0385
Echinococcus multilocularis sodium:dicarboxylate symporter 0.1834 1 1
Echinococcus multilocularis tumor protein p63 0.0328 0.1688 0.1688
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0198 0.0863
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0813 0.4366 0.4366
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0583 0.3097 0.3096
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.1523 1
Brugia malayi beta-lactamase family protein 0.0186 0.0906 0.0904
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0108 0.0107

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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