Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0038 | 0.0194 | 0.0331 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.014 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0755 | 0.1292 |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.3293 | 0.5636 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.3401 | 0.582 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0038 | 0.0194 | 0.0331 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0161 | 0.3981 | 0.6812 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0184 | 0.0315 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.8397 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0038 | 0.0194 | 0.0331 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0142 | 0.3401 | 0.582 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0331 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0184 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0214 | 0.0366 |
Echinococcus granulosus | acetylcholinesterase | 0.0222 | 0.5844 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0038 | 0.0194 | 0.0331 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.8397 | 1 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0305 | 0.8397 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.8397 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.8397 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.3401 | 0.582 |
Brugia malayi | Carboxylesterase family protein | 0.0222 | 0.5844 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0184 | 0.0053 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.014 | 0.024 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0217 | 0.5704 | 0.9762 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.0755 | 0.1292 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0184 | 0.0315 |
Schistosoma mansoni | acetylcholinesterase | 0.0038 | 0.0194 | 0.0331 |
Echinococcus multilocularis | acetylcholinesterase | 0.0222 | 0.5844 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0161 | 0.3981 | 0.6812 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0038 | 0.0194 | 0.0331 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0184 | 0.0315 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0184 | 0.0315 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0038 | 0.0194 | 0.0015 |
Mycobacterium ulcerans | transglutaminase family protein | 0.0181 | 0.4578 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0222 | 0.5844 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0038 | 0.0194 | 0.0331 |
Echinococcus granulosus | acetylcholinesterase | 0.0222 | 0.5844 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0184 | 0.0315 |
Schistosoma mansoni | gliotactin | 0.0038 | 0.0194 | 0.0331 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0149 | 0.3613 | 0.7804 |
Onchocerca volvulus | 0.0247 | 0.6624 | 0.6624 | |
Brugia malayi | Carboxylesterase family protein | 0.0038 | 0.0194 | 0.0331 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0038 | 0.0194 | 0.0015 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.8397 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0184 | 0.0315 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0305 | 0.8397 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0038 | 0.0194 | 0.0021 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0222 | 0.5844 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.8397 | 1 |
Echinococcus granulosus | Transglutaminase | 0.0181 | 0.4578 | 0.7835 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0161 | 0.3981 | 0.6812 |
Echinococcus multilocularis | neuroligin | 0.0038 | 0.0194 | 0.0331 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.8397 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0181 | 0.4578 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0331 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0163 | 0.4039 | 0.6912 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0163 | 0.4039 | 0.6912 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.4578 | 0.7835 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0163 | 0.4039 | 0.6912 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.014 | 0.024 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.014 | 0.024 |
Mycobacterium tuberculosis | Long conserved protein | 0.0181 | 0.4578 | 0.7156 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0184 | 0.0053 |
Onchocerca volvulus | 0.0038 | 0.0194 | 0.0194 | |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0142 | 0.3401 | 0.582 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0184 | 0.0315 |
Trichomonas vaginalis | set domain proteins, putative | 0.0247 | 0.6624 | 0.7853 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0184 | 0.0053 |
Trichomonas vaginalis | conserved hypothetical protein | 0.018 | 0.4565 | 0.5359 |
Echinococcus multilocularis | acetylcholinesterase | 0.0222 | 0.5844 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0038 | 0.0194 | 0.0065 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0163 | 0.4039 | 0.6912 |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.3293 | 0.5636 |
Brugia malayi | Pre-SET motif family protein | 0.0217 | 0.5704 | 0.9762 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0331 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.3401 | 0.582 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.3401 | 0.582 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0181 | 0.4578 | 0.7156 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 0.3981 | 0.6812 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0184 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.5844 | 1 |
Echinococcus multilocularis | Transglutaminase | 0.0181 | 0.4578 | 0.7835 |
Brugia malayi | Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog | 0.0185 | 0.472 | 0.8078 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0038 | 0.0194 | 0.0331 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0184 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0038 | 0.0194 | 0.0331 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0184 | 0.0315 |
Echinococcus granulosus | neuroligin | 0.0038 | 0.0194 | 0.0331 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0331 |
Onchocerca volvulus | 0.0038 | 0.0194 | 0.0194 | |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0163 | 0.4039 | 0.6912 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0184 | 0.0315 |
Mycobacterium ulcerans | hypothetical protein | 0.0181 | 0.4578 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0184 | 0.0315 |
Trichomonas vaginalis | peptide N-glycanase, putative | 0.0181 | 0.4578 | 0.5375 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0184 | 0.0315 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0305 | 0.8397 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0038 | 0.0194 | 0.0331 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0163 | 0.4039 | 0.6912 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0184 | 0.0315 |
Brugia malayi | Carboxylesterase family protein | 0.0038 | 0.0194 | 0.0331 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0184 | 0.0315 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0331 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0214 | 0.0366 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0038 | 0.0194 | 0.0015 |
Loa Loa (eye worm) | carboxylesterase | 0.0038 | 0.0194 | 0.0331 |
Onchocerca volvulus | 0.0038 | 0.0194 | 0.0194 | |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0038 | 0.0194 | 0.0331 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0194 | 0.0331 |
Echinococcus granulosus | carboxylesterase 5A | 0.0222 | 0.5844 | 1 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0149 | 0.3613 | 0.7804 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.5844 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.014 | 0.7604 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.3401 | 0.582 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0305 | 0.8397 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.0755 | 0.1292 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0184 | 0.0053 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.3401 | 0.582 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0181 | 0.4578 | 0.7156 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0184 | 0.0053 |
Onchocerca volvulus | 0.0037 | 0.0184 | 0.0184 | |
Mycobacterium tuberculosis | Conserved protein | 0.0181 | 0.4578 | 0.7156 |
Onchocerca volvulus | 0.0093 | 0.19 | 0.19 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0222 | 0.5844 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.3401 | 0.582 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0184 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0331 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0214 | 0.0366 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0181 | 0.4578 | 1 |
Brugia malayi | Thioredoxin family protein | 0.0181 | 0.4578 | 0.7835 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.0755 | 0.1292 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0149 | 0.3613 | 0.5585 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0038 | 0.0194 | 0.0331 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 0.3981 | 0.6812 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0181 | 0.4578 | 0.7156 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0038 | 0.0194 | 0.0065 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0184 | 0.0315 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0038 | 0.0194 | 0.0331 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0305 | 0.8397 | 1 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0163 | 0.4039 | 0.6912 |
Mycobacterium ulcerans | hypothetical protein | 0.0181 | 0.4578 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0184 | 0.0315 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.472 | 0.8078 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0184 | 0.0315 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.014 | 0.024 |
Brugia malayi | Carboxylesterase family protein | 0.0038 | 0.0194 | 0.0331 |
Brugia malayi | Carboxylesterase family protein | 0.0222 | 0.5844 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0184 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.4039 | 0.6912 |
Mycobacterium ulcerans | putative transglutaminase-like protein | 0.0181 | 0.4578 | 1 |
Onchocerca volvulus | Putative nachr subunit | 0.0163 | 0.4039 | 0.4039 |
Loa Loa (eye worm) | carboxylesterase | 0.0038 | 0.0194 | 0.0331 |
Loa Loa (eye worm) | carboxylesterase | 0.0222 | 0.5844 | 1 |
Onchocerca volvulus | 0.0038 | 0.0194 | 0.0194 | |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0238 | 0.6324 | 1 |
Onchocerca volvulus | 0.0037 | 0.0184 | 0.0184 | |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0163 | 0.4039 | 0.6912 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0184 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0184 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0331 |
Onchocerca volvulus | 0.0038 | 0.0194 | 0.0194 | |
Onchocerca volvulus | 0.0037 | 0.0184 | 0.0184 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.