Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0834 | 0.0659 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0016 | 0.0187 | 0.0187 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Brugia malayi | Muscleblind-like protein | 0.0145 | 0.4658 | 1 |
Onchocerca volvulus | 0.0016 | 0.0187 | 1 | |
Schistosoma mansoni | bromodomain containing protein | 0.0061 | 0.1756 | 0.1756 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0138 | 0.0138 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.1164 | 0.1164 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0016 | 0.0187 | 0.0187 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.0913 | 0.1961 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0338 | 0.0338 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0017 | 0.0197 | 0.0011 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0017 | 0.0197 | 0.0197 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.0187 | 0.4547 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0187 | 0.0401 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0338 | 0.3703 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.1773 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.1164 | 0.1164 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0187 | 0.0187 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0187 | 0.0401 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.1773 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0016 | 0.0187 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0382 | 0.0199 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0338 | 0.8226 |
Echinococcus multilocularis | snurportin 1 | 0.0298 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.041 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0073 | 0.2151 | 0.4617 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0594 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.2006 | 0.2006 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0016 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0318 | 0.0318 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0338 | 0.1221 |
Onchocerca volvulus | 0.0016 | 0.0187 | 1 | |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0282 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0197 | 0.0197 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0197 | 0.0197 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0016 | 0.0187 | 0.0187 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0197 | 0.0197 |
Schistosoma mansoni | hypothetical protein | 0.0298 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0282 | 0.0282 |
Onchocerca volvulus | 0.0016 | 0.0187 | 1 | |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0197 | 0.0197 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.1164 | 0.1164 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0594 | 0.1276 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0218 | 0.0218 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0594 | 1 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0338 | 0.1221 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.1164 | 0.1164 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.1164 | 0.1164 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0197 | 0.0197 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0197 | 0.0011 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0382 | 0.0382 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.1773 | 1 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0338 | 0.8226 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0338 | 0.1221 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.0187 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0594 | 0.2791 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0122 | 0.3866 | 0.375 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0282 | 0.0097 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0187 | 0.0298 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.1773 | 1 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0594 | 0.0415 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.1773 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.106 | 0.106 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0187 | 0.0401 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.1773 | 1 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0187 | 0.0298 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.1773 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.0187 | 0.4547 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0187 | 0.0401 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.1773 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.1164 | 0.0996 |
Echinococcus multilocularis | muscleblind protein | 0.0145 | 0.4658 | 0.4557 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.4658 | 0.4658 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.4658 | 0.4658 |
Echinococcus granulosus | muscleblind protein | 0.0145 | 0.4658 | 0.4658 |
Onchocerca volvulus | 0.0016 | 0.0187 | 1 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.1773 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Loa Loa (eye worm) | ctsf protein | 0.0016 | 0.0187 | 0.0187 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0318 | 0.0318 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.041 | 0.1667 |
Loa Loa (eye worm) | fibroinase | 0.0016 | 0.0187 | 0.0187 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0132 | 0.4207 | 0.4097 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0187 | 0.0187 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0594 | 0.0594 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0197 | 0.0197 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.041 | 1 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0338 | 0.5 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0338 | 0.3703 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0187 | 0.0401 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0338 | 0.0338 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0187 | 0.0298 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.1773 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.1635 | 0.1476 |
Leishmania major | cysteine peptidase A (CPA) | 0.0016 | 0.0187 | 0.0298 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Entamoeba histolytica | cysteine protease, putative | 0.0016 | 0.0187 | 0.4547 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0016 | 0.0187 | 0.0298 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0594 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.1773 | 1 |
Onchocerca volvulus | 0.0016 | 0.0187 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0338 | 0.3703 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.1773 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.1773 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.041 | 0.1667 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0916 | 0.0916 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0187 | 0.0401 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.1635 | 0.1635 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0834 | 0.0834 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0996 | 0.0996 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0187 | 0.0298 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0049 | 0.1313 | 0.7185 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0145 | 0.4658 | 0.4557 |
Schistosoma mansoni | ran | 0.0021 | 0.0338 | 0.0338 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0594 | 0.0594 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.1773 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.4207 | 0.4207 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0338 | 0.0725 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.1773 | 1 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0298 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.4207 | 0.4207 |
Onchocerca volvulus | 0.0016 | 0.0187 | 1 | |
Onchocerca volvulus | 0.0016 | 0.0187 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0122 | 0.3866 | 0.3866 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.0187 | 1 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.0462 | 0.0992 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0187 | 0.0401 |
Brugia malayi | RNA, U transporter 1 | 0.0079 | 0.2387 | 0.5123 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.1773 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0056 | 0.1586 | 0.8859 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0594 | 0.2791 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0138 | 0.0138 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.1164 | 0.1164 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.041 | 1 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.041 | 1 |
Schistosoma mansoni | ran | 0.0021 | 0.0338 | 0.0338 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.1773 | 1 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0594 | 0.0594 |
Loa Loa (eye worm) | cysteine protease | 0.0016 | 0.0187 | 0.0187 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.1773 | 1 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0338 | 0.0154 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.1164 | 0.0996 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0122 | 0.3866 | 0.3866 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0187 | 0.0187 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0382 | 0.0382 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0187 | 0.4547 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0338 | 0.1221 |
Echinococcus granulosus | cathepsin l1 | 0.0016 | 0.0187 | 0.0187 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.1164 | 0.2499 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0187 | 0.0298 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.