Detailed information for compound 573597

Basic information

Technical information
  • TDR Targets ID: 573597
  • Name: methyl 5-[[(1S,4aS,5R,6S,8aS)-6-hydroxy-5-(3- hydroxy-3-methyl-butyl)-5,8a-dimethyl-2-methy lene-decalin-1-yl]methyl]-6-methoxy-2-methyl- 4-oxo-pyran-3-carboxylate
  • MW: 490.629 | Formula: C28H42O7
  • H donors: 2 H acceptors: 4 LogP: 4.19 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1c(C)oc(c(c1=O)C[C@H]1C(=C)CC[C@H]2[C@@]1(C)CC[C@@H]([C@]2(C)CCC(O)(C)C)O)OC
  • InChi: 1S/C28H42O7/c1-16-9-10-20-27(5,12-11-21(29)28(20,6)14-13-26(3,4)32)19(16)15-18-23(30)22(24(31)33-7)17(2)35-25(18)34-8/h19-21,29,32H,1,9-15H2,2-8H3/t19-,20-,21-,27-,28+/m0/s1
  • InChiKey: IUNGBSYMDFEAMS-KPRONASWSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-[[(1S,4aS,5R,6S,8aS)-6-hydroxy-5-(3-hydroxy-3-methylbutyl)-5,8a-dimethyl-2-methylene-1-decalinyl]methyl]-6-methoxy-2-methyl-4-oxo-3-pyrancarboxylic acid methyl ester
  • methyl 5-[[(1S,4aS,5R,6S,8aS)-6-hydroxy-5-(3-hydroxy-3-methyl-butyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]methyl]-6-methoxy-2-methyl-4-oxo-pyran-3-carboxylate
  • 5-[[(1S,4aS,5R,6S,8aS)-6-hydroxy-5-(3-hydroxy-3-methyl-butyl)-5,8a-dimethyl-2-methylene-decalin-1-yl]methyl]-4-keto-6-methoxy-2-methyl-pyran-3-carboxylic acid methyl ester
  • methyl 5-[[(1S,4aS,5R,6S,8aS)-6-hydroxy-5-(3-hydroxy-3-methylbutyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]methyl]-6-methoxy-2-methyl-4-oxopyran-3-carboxylate
  • colletotrichin
  • 61235-00-5
  • 4H-Pyran-3-carboxylic acid, 5-((decahydro-6-hydroxy-5-(3-hydroxy-3-methylbutyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl)methyl)-6-methoxy-2-methyl-4-oxo-, methyl ester, (1alpha,4aalpha,5alpha,6alpha,8abeta)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0058 0.0247 0.0247
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0026 0.007 0.0149
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0077 0.0351 0.0753
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Brugia malayi conserved hypotetical protein 0.0281 0.1478 0.3166
Brugia malayi Polyprenyl synthetase family protein 0.012 0.0587 0.1257
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.003 0.0093 0.0109
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0142 0.0697
Onchocerca volvulus 0.0048 0.0191 0.0593
Brugia malayi hypothetical protein 0.0058 0.0247 0.0528
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0021 0.0044
Echinococcus granulosus biogenic amine 5HT receptor 0.0058 0.0247 0.029
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.003 0.0093 0.0457
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0596 0.3217 0.3785
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Echinococcus granulosus G protein coupled receptor 139 0.0058 0.0247 0.029
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0142 0.0322
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0023 0.0023
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.003 0.0093 0.0937
Leishmania major polyprenyl synthase, putative 0.003 0.0093 0.0155
Brugia malayi neuropeptide F receptor 0.0058 0.0247 0.0528
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0126 0.0149
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Leishmania major cytochrome p450-like protein 0.002 0.0039 0.0038
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0142 0.0697
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0154 0.0779 0.3833
Echinococcus multilocularis musashi 0.0061 0.0261 0.0261
Echinococcus granulosus potassium voltage gated channel subfamily H 0.004 0.0147 0.0173
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0044 0.0169 0.0169
Echinococcus multilocularis neuropeptide Y receptor 0.0058 0.0247 0.0247
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0281 0.1478 0.174
Mycobacterium ulcerans electron transfer protein 0.0026 0.007 0.0242
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0191 0.3001
Brugia malayi G-protein coupled receptor 0.0058 0.0247 0.0528
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0191 0.0224
Schistosoma mansoni hypothetical protein 0.0058 0.0247 0.029
Schistosoma mansoni nuclear hormone receptor 0.0281 0.1478 0.174
Loa Loa (eye worm) hypothetical protein 0.0315 0.1665 0.3564
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0058 0.0247 0.029
Brugia malayi Serotonin receptor 0.0058 0.0247 0.0528
Loa Loa (eye worm) hypothetical protein 0.0035 0.0118 0.0252
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.002 0.0039 0.007
Brugia malayi cytochrome P450 0.002 0.0039 0.0083
Plasmodium vivax amine transporter, putative 0.0048 0.0191 0.3001
Echinococcus granulosus g protein coupled receptor 0.0058 0.0247 0.029
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0142 0.2976
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0023 0.0006
Schistosoma mansoni amine GPCR 0.0058 0.0247 0.029
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0315 0.1665 0.3564
Schistosoma mansoni aldehyde dehydrogenase 0.0137 0.0681 0.0801
Brugia malayi Nuclear hormone receptor-like 1 0.0596 0.3217 0.6888
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0182 0.0348
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0042 0.0042
Echinococcus granulosus tm gpcr rhodopsin 0.1024 0.5581 0.6567
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Schistosoma mansoni hypothetical protein 0.006 0.0259 0.0305
Echinococcus granulosus Adrenodoxin mitochondrial 0.0026 0.007 0.0082
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.002 0.0039 0.0134
Brugia malayi isocitrate dehydrogenase 0.0017 0.0021 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0083 0.0188
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0088 0.0088
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0191 0.0224
Trichomonas vaginalis Ferredoxin 2 0.0026 0.007 0.0159
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0142 0.0142
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0022 0.0026
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0169 0.0199
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0596 0.3217 0.3785
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0063 0.0123
Onchocerca volvulus 0.011 0.0532 0.1654
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0381 0.2031 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0596 0.3217 0.6888
Loa Loa (eye worm) hypothetical protein 0.0596 0.3217 0.6888
Echinococcus multilocularis acetylcholinesterase 0.0079 0.0363 0.0363
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0077 0.0351 0.0414
Loa Loa (eye worm) hypothetical protein 0.0048 0.0191 0.0408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0023 0.0053
Leishmania major solanesyl-diphosphate synthase, putative 0.003 0.0093 0.0155
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.003 0.0093 0.0199
Loa Loa (eye worm) hypothetical protein 0.0046 0.0182 0.039
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.002 0.0039 0.019
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0042 0.0077
Echinococcus granulosus thyroid hormone receptor alpha 0.0281 0.1478 0.174
Brugia malayi ecdysone receptor 0.0281 0.1478 0.3166
Schistosoma mansoni nuclear receptor 0.0281 0.1478 0.174
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0142 0.0322
Echinococcus granulosus nuclear factor of activated T cells 5 0.0086 0.0401 0.0471
Schistosoma mansoni cytochrome P450 0.002 0.0039 0.0045
Loa Loa (eye worm) TK protein kinase 0.004 0.0145 0.0311
Loa Loa (eye worm) hypothetical protein 0.0315 0.1665 0.3564
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.012 0.0274
Schistosoma mansoni hypothetical protein 0.0017 0.0021 0.0024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0596 0.3217 0.6888
Echinococcus granulosus dna polymerase kappa 0.0021 0.0042 0.0049
Onchocerca volvulus 0.0058 0.0247 0.0767
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0282 0.1484 0.1746
Echinococcus multilocularis ferredoxin adrenodoxin 0.0026 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0156 0.0356
Loa Loa (eye worm) hypothetical protein 0.0037 0.013 0.0278
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.0138 0.0138
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0022 0.0022
Onchocerca volvulus 0.048 0.2575 0.8006
Onchocerca volvulus Protein ultraspiracle homolog 0.0596 0.3217 1
Schistosoma mansoni hypothetical protein 0.0043 0.0162 0.0191
Loa Loa (eye worm) hypothetical protein 0.0083 0.0385 0.0824
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0042 0.0045
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.002 0.0039 0.0134
Loa Loa (eye worm) hypothetical protein 0.0017 0.0021 0.0044
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.012 0.0587 0.1336
Loa Loa (eye worm) hypothetical protein 0.0039 0.0142 0.0303
Onchocerca volvulus 0.0281 0.1478 0.4596
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0167 0.0197
Mycobacterium ulcerans epimerase 0.0022 0.0047 0.0162
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Schistosoma mansoni adrenodoxin 0.0026 0.007 0.0082
Echinococcus granulosus allatostatin A receptor 0.0058 0.0247 0.029
Brugia malayi G protein-coupled receptor 0.0058 0.0247 0.0528
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0058 0.0247 0.029
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0042 0.009
Echinococcus granulosus sex peptide receptor 0.0058 0.0247 0.029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0247 0.0247
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Echinococcus granulosus RUN 0.0043 0.0162 0.0191
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0681 0.236
Echinococcus multilocularis lamin dm0 0.0061 0.0261 0.0261
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0075 0.0171
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0048 0.0191 0.0408
Onchocerca volvulus 0.0058 0.0247 0.0767
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0536 0.2884 1
Schistosoma mansoni amine GPCR 0.0058 0.0247 0.029
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.002 0.0039 0.0134
Brugia malayi hypothetical protein 0.0315 0.1665 0.3564
Leishmania major hypothetical protein, conserved 0.0039 0.0142 0.026
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0162 0.0191
Trypanosoma cruzi adrenodoxin precursor, putative 0.0026 0.007 0.0105
Echinococcus granulosus nuclear receptor nhr 48 0.0281 0.1478 0.174
Trypanosoma cruzi adrenodoxin precursor, putative 0.0026 0.007 0.0105
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.002 0.0039 0.019
Echinococcus granulosus alpha 1A adrenergic receptor 0.0058 0.0247 0.029
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Schistosoma mansoni lipoxygenase 0.0111 0.0537 0.0632
Brugia malayi hypothetical protein 0.0043 0.0162 0.0347
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0075 0.0171
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0191 0.0224
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0137 0.0681 0.0681
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0021 0.0021
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0089 0.0146
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0058 0.0247 0.029
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0041 0.0154 0.0319
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.002 0.0039 0.019
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0019 0.0019
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0042 0.0049
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0281 0.1478 0.3166
Loa Loa (eye worm) carboxylesterase 0.0079 0.0363 0.0777
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0023 0.0037
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0041 0.0154 0.0331
Toxoplasma gondii target of rapamycin (TOR), putative 0.0039 0.0142 0.1831
Loa Loa (eye worm) hypothetical protein 0.0078 0.0358 0.0766
Trypanosoma brucei Emopamil binding protein, putative 0.016 0.0812 0.1729
Schistosoma mansoni histamine h1 receptor 0.0058 0.0247 0.029
Brugia malayi SET domain containing protein 0.0015 0.0009 0.002
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0048 0.0191 0.0224
Schistosoma mansoni hypothetical protein 0.0017 0.0021 0.0024
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0162 0.2497
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0247 0.0247
Loa Loa (eye worm) hypothetical protein 0.011 0.0532 0.1139
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0042 0.0077
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0247 0.029
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0058 0.0247 0.0247
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0247 0.0247
Echinococcus multilocularis neuropeptide receptor A26 0.0556 0.2998 0.2998
Leishmania major ferredoxin 2fe-2s-like protein 0.0026 0.007 0.0105
Brugia malayi nuclear receptor RXR 0.0315 0.1665 0.3564
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0026 0.007 0.0343
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0247 0.029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0075 0.0171
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.002 0.0039 0.0134
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0249 0.1302 0.641
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0596 0.3217 0.3785
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0023 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0142 0.026
Onchocerca volvulus 0.0039 0.0142 0.044
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.004 0.0147 0.0314
Echinococcus multilocularis dro:myosuppressin receptor 0.0058 0.0247 0.0247
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0247 0.029
Echinococcus granulosus intermediate filament protein 0.0061 0.0261 0.0307
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.003 0.0093 0.0109
Loa Loa (eye worm) hypothetical protein 0.0021 0.0042 0.0089
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.016 0.0812 0.1702
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0142 0.0167
Brugia malayi hypothetical protein 0.0043 0.0162 0.0347
Echinococcus granulosus phospholipase D 0.0106 0.0512 0.0602
Brugia malayi Dopamine receptor 0.0058 0.0247 0.0528
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.003 0.0093 0.0199
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0281 0.1478 0.174
Echinococcus granulosus biogenic amine 5HT receptor 0.0058 0.0247 0.029
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0281 0.1478 0.3166
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0075 0.0171
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0142 0.0697
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0042 0.0049
Schistosoma mansoni glutathione synthetase 0.003 0.0093 0.0109
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.003 0.0093 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0247 0.029
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0026 0.007 0.6178
Loa Loa (eye worm) hypothetical protein 0.0039 0.0142 0.0303
Mycobacterium ulcerans electron transfer protein FdxB 0.0026 0.007 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0142 0.0322
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.003 0.0093 0.0155
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0315 0.1665 0.1959
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0042 0.0205
Trichomonas vaginalis glucosylceramidase, putative 0.0581 0.3134 0.7138
Trichomonas vaginalis Ferredoxin 3 0.0026 0.007 0.0159
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0042 0.0077
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.003 0.0093 0.0322
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0106 0.0226
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0026 0.007 0.0105
Trypanosoma brucei electron transfer protein, putative 0.0026 0.007 0.0137
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0141 0.0166
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.012 0.0587 0.858
Schistosoma mansoni nuclear hormone receptor 0.0596 0.3217 0.3785
Trypanosoma cruzi adrenodoxin precursor, putative 0.0026 0.007 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0142 0.026
Loa Loa (eye worm) hypothetical protein 0.0596 0.3217 0.6888
Echinococcus granulosus tyrosine kinase 0.004 0.0145 0.0171
Schistosoma mansoni lipoxygenase 0.0188 0.0962 0.1132
Brugia malayi Steroid receptor seven-up type 2 0.0596 0.3217 0.6888
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.013 0.0278
Loa Loa (eye worm) hypothetical protein 0.0039 0.0142 0.0303
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.0022
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0019 0.0032 0.0205
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0042 0.0077
Schistosoma mansoni zinc finger protein 0.0281 0.1478 0.174
Loa Loa (eye worm) hypothetical protein 0.0101 0.0483 0.1034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0247 0.029
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.003 0.0093 0.0937
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0216 0.0491
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Echinococcus multilocularis dnaJ subfamily B 0.092 0.5008 0.5008
Loa Loa (eye worm) hypothetical protein 0.0282 0.1484 0.3177
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.002 0.0039 0.019
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0086 0.0401 0.0401
Echinococcus granulosus g-protein coupled receptor 0.0058 0.0247 0.029
Treponema pallidum quinoline 2-oxidoreductase 0.0128 0.0635 0.3898
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0046 0.0182 0.0214
Echinococcus granulosus neuropeptide Y receptor 0.0058 0.0247 0.029
Echinococcus multilocularis G-protein coupled receptor, putative 0.0058 0.0247 0.0247
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0021 0.0021
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0042 0.0089
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0041 0.0154 0.2361
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1024 0.5581 0.5581
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0596 0.3217 0.6888
Onchocerca volvulus 0.0058 0.0247 0.0767
Echinococcus multilocularis phospholipase d3 0.0023 0.0051 0.0051
Treponema pallidum hypothetical protein 0.0108 0.0524 0.3099
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Toxoplasma gondii ABC1 family protein 0.0039 0.0142 0.1832
Brugia malayi G-protein coupled receptor 0.0058 0.0247 0.0528
Onchocerca volvulus 0.0278 0.1461 0.4541
Schistosoma mansoni hypothetical protein 0.0017 0.0021 0.0024
Brugia malayi intermediate filament protein 0.0061 0.0261 0.0559
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.002 0.0039 0.019
Schistosoma mansoni coup transcription factor 0.0596 0.3217 0.3785
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0052 0.0216 0.3181
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0058 0.0247 0.0247
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0048 0.0191 0.0224
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Echinococcus multilocularis neuropeptide FF receptor 2 0.0058 0.0247 0.0247
Echinococcus granulosus phospholipase D1 0.012 0.0589 0.0693
Toxoplasma gondii ferodoxin FD 0.0026 0.007 0.0743
Echinococcus granulosus serotonin transporter 0.0282 0.1484 0.1746
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0052 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Schistosoma mansoni hypothetical protein 0.0037 0.013 0.0153
Trichomonas vaginalis set domain proteins, putative 0.0278 0.146 0.3325
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0048 0.0191 0.0224
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0023 0.0006
Entamoeba histolytica hypothetical protein 0.0039 0.0141 0.1823
Brugia malayi ecdysteroid receptor 0.0596 0.3217 0.6888
Loa Loa (eye worm) nuclear hormone receptor 0.0281 0.1478 0.3166
Schistosoma mansoni alpha-1 adrenergic receptor 0.0058 0.0247 0.029
Brugia malayi CXXC zinc finger family protein 0.0065 0.0283 0.0606
Loa Loa (eye worm) TYRA-2 protein 0.0058 0.0247 0.0528
Loa Loa (eye worm) cytochrome P450 family protein 0.004 0.0147 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0156 0.0356
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.004 0.0145 0.0171
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0351 0.0711
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0021 0.0102
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0026 0.007 0.1063
Leishmania major farnesyl pyrophosphate synthase 0.012 0.0587 0.1218
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0019 0.0022
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0021 0.0021
Mycobacterium tuberculosis Probable oxidoreductase 0.0026 0.007 0.0343
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0169 0.0199
Echinococcus multilocularis geminin 0.0184 0.094 0.094
Onchocerca volvulus 0.0043 0.0162 0.0504
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0016
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0162 0.0162
Echinococcus granulosus geminin 0.0184 0.094 0.1106
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0058 0.0247 0.0247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0023 0.0053
Brugia malayi Melatonin receptor type 1A 0.0058 0.0247 0.0528
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0142 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0016
Entamoeba histolytica hypothetical protein 0.0039 0.0141 0.1823
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.016 0.0812 0.1702
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.012 0.0587 0.0587
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0216 0.0462
Brugia malayi Nuclear hormone receptor-like 1 0.0315 0.1665 0.3564
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0058 0.0247 0.029
Mycobacterium ulcerans oxidoreductase 0.0026 0.007 0.0242
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.002 0.0039 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0097 0.0222
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0026 0.007 0.0149
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0044 0.0051
Brugia malayi beta-lactamase 0.0039 0.0142 0.0303
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0058 0.0247 0.0247
Brugia malayi Phospholipase D. Active site motif family protein 0.0042 0.0157 0.0337
Echinococcus multilocularis GPCR, family 2 0.0017 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0028 0.0082 0.0175
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.003 0.0093 0.1275
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0273 0.1434 0.4971
Echinococcus multilocularis neuropeptide Y receptor 0.0058 0.0247 0.0247
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0129 0.0639 0.0752
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0041 0.0154 0.0287
Schistosoma mansoni steroid hormone receptor ad4bp 0.0596 0.3217 0.3785
Echinococcus multilocularis nuclear receptor nhr 48 0.0281 0.1478 0.1478
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.003 0.0093 0.0322
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0596 0.3217 0.6888
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0041 0.0154 0.0154
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0042 0.0077
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0132 0.0301
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0191 0.0408
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0021 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0596 0.3217 0.6888
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.002 0.0039 0.0134
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0596 0.3217 0.3217
Echinococcus multilocularis carboxylesterase 5A 0.0079 0.0363 0.0363
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0089 0.1029
Loa Loa (eye worm) hypothetical protein 0.0282 0.1484 0.3177
Giardia lamblia GTOR 0.0052 0.0216 0.3193
Schistosoma mansoni sodium/chloride dependent transporter 0.0282 0.1484 0.1746
Brugia malayi nuclear receptor NHR-88 0.0281 0.1478 0.3166
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.002 0.0039 0.0134
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.002 0.0039 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0156 0.0356
Toxoplasma gondii cytochrome p450 superfamily protein 0.002 0.0039 0.0271
Schistosoma mansoni myosin xvIII 0.0058 0.0247 0.029
Echinococcus granulosus dnaJ subfamily B 0.092 0.5008 0.5892
Schistosoma mansoni adrenodoxin 0.0026 0.007 0.0082
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0142 0.0291
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0089 0.0177
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0281 0.1478 0.1478
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0099 0.0226
Brugia malayi Dopamine receptor protein 1 0.0058 0.0247 0.0528
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0596 0.3217 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0058 0.0247 0.029
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.002 0.0039 0.0134
Echinococcus granulosus serotonin receptor 0.0058 0.0247 0.029
Trichomonas vaginalis glucosylceramidase, putative 0.0581 0.3134 0.7138
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.003 0.0093 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0596 0.3217 0.3785
Mycobacterium ulcerans hypothetical protein 0.0039 0.0142 0.0491
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0046 0.0087
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0042 0.0045
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Mycobacterium tuberculosis Possible oxygenase 0.0026 0.007 0.0343
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0142 0.0697
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.004
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0019 0.0022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0596 0.3217 0.3217
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0581 0.3134 0.6712
Echinococcus granulosus somatostatin receptor 0.0058 0.0247 0.029
Onchocerca volvulus 0.0111 0.0541 0.1681
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0247 0.029
Brugia malayi hypothetical protein 0.0058 0.0247 0.0528
Brugia malayi Pre-SET motif family protein 0.0244 0.1275 0.2729
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0169 0.0169
Schistosoma mansoni opsin-like receptor 0.0058 0.0247 0.029
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.003 0.0093 0.0457
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0042 0.0144
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.002 0.0039 0.0134
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0048 0.0191 0.4493
Trichomonas vaginalis glucosylceramidase, putative 0.0581 0.3134 0.7138
Loa Loa (eye worm) hypothetical protein 0.0039 0.0142 0.0303
Onchocerca volvulus 0.0061 0.0261 0.0812
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0016
Brugia malayi Cytochrome P450 family protein 0.002 0.0039 0.0083
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0019 0.0032 0.0205
Schistosoma mansoni biogenic amine receptor 0.0058 0.0247 0.029
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0042 0.0045
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.002 0.0039 0.0134
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0041 0.0154 0.0182
Schistosoma mansoni hypothetical protein 0.0017 0.0021 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0381 0.2031 0.4626
Echinococcus multilocularis neuropeptide receptor 0.0058 0.0247 0.0247
Brugia malayi hypothetical protein 0.0058 0.0247 0.0528
Trypanosoma cruzi solanesyl-diphosphate synthase 0.003 0.0093 0.0155
Schistosoma mansoni hypothetical protein 0.0039 0.0141 0.0166
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0596 0.3217 0.3217
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.012 0.0587 0.1218
Echinococcus multilocularis ecdysone induced protein 78C 0.0596 0.3217 0.3217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0097 0.0222
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0015 0.0017
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.004 0.0147 0.0511
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0142 0.0322
Onchocerca volvulus 0.0058 0.0247 0.0767
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0058 0.0247 0.0528
Brugia malayi Serotonin receptor 0.0595 0.321 0.6874
Trypanosoma brucei cardiolipin synthetase 0.0042 0.0157 0.0325
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0247 0.029
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.003 0.0093 0.172
Echinococcus granulosus carboxylesterase 5A 0.0079 0.0363 0.0427
Echinococcus multilocularis microtubule associated protein 2 0.1553 0.8499 0.8499
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0026 0.007 0.0149
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0083 0.0188
Brugia malayi follicle stimulating hormone receptor 0.0058 0.0247 0.0528
Trypanosoma cruzi cardiolipin synthetase, putative 0.0042 0.0157 0.0294
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.002 0.0039 0.0134
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0162 0.0191
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0021 0.0024
Echinococcus granulosus tm gpcr rhodopsin 0.0662 0.3581 0.4213
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0247 0.029
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0016
Echinococcus granulosus sodium and chloride dependent glycine 0.0048 0.0191 0.0224
Schistosoma mansoni biogenic amine (5HT) receptor 0.0058 0.0247 0.029
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0052 0.0216 0.0254
Echinococcus granulosus tyrosine protein kinase Src42A 0.0044 0.0169 0.0199
Onchocerca volvulus 0.0026 0.007 0.0217
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0162 0.0347
Echinococcus multilocularis RUN 0.0043 0.0162 0.0162
Brugia malayi hypothetical protein 0.0019 0.0032 0.0069
Echinococcus granulosus ferredoxin 0.0026 0.007 0.0082
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0052 0.0216 0.0419
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0182 0.039
Trypanosoma brucei cytochrome P450, putative 0.004 0.0147 0.0304
Loa Loa (eye worm) hypothetical protein 0.0054 0.0224 0.048
Onchocerca volvulus 0.016 0.0812 0.2525
Onchocerca volvulus 0.0043 0.0162 0.0504
Brugia malayi nuclear hormone receptor 0.0596 0.3217 0.6888
Schistosoma mansoni netrin receptor unc5 0.0017 0.0019 0.0022
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0041 0.0154 0.0331
Echinococcus granulosus 7tm_1 domain containing protein 0.0058 0.0247 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0247 0.029
Echinococcus granulosus acetylcholinesterase 0.0079 0.0363 0.0427
Loa Loa (eye worm) hypothetical protein 0.0403 0.2152 0.4607
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0281 0.1478 0.174
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0044 0.0169 0.0169
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.012 0.0587 0.2035
Brugia malayi Death domain containing protein 0.0017 0.0019 0.004
Toxoplasma gondii aldehyde dehydrogenase 0.0137 0.0681 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0403 0.2152 0.4607
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0044 0.0169 0.0169
Schistosoma mansoni hypothetical protein 0.002 0.0039 0.0045
Brugia malayi hypothetical protein 0.0281 0.1478 0.3166
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0132 0.0301
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0244 0.1275 0.2729
Toxoplasma gondii histone lysine methyltransferase SET1 0.0124 0.0609 0.8919
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0021 0.0021
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0058 0.0247 0.0528
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0129 0.0639 0.133
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.002 0.0039 0.0134
Loa Loa (eye worm) intermediate filament protein 0.0061 0.0261 0.0559
Loa Loa (eye worm) hypothetical protein 0.048 0.2575 0.5515
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0058 0.0247 0.0247
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0041 0.0154 0.0331
Brugia malayi Tachykinin-like peptides receptor 99D 0.0058 0.0247 0.0528
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.002 0.0039 0.0134
Brugia malayi Cytochrome P450 family protein 0.004 0.0147 0.0316
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0046 0.0182 0.0348
Schistosoma mansoni sodium-dependent amino acid transporter 0.0048 0.0191 0.0224
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0247 0.0247
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0022 0.0022
Leishmania major cytochrome p450-like protein 0.004 0.0147 0.0272
Loa Loa (eye worm) CYP4Cod1 0.004 0.0147 0.0316
Mycobacterium leprae Probable lipase LipE 0.0039 0.0142 0.2976
Brugia malayi hypothetical protein 0.0058 0.0247 0.0528
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0142 0.0322
Loa Loa (eye worm) SRC-1 0.0044 0.0169 0.0361
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0042 0.0049
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0191 0.0224
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0703 0.3807 0.4479
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0044 0.0044
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0041 0.0154 0.0287
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0021 0.0032
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0026 0.007 0.0217
Onchocerca volvulus 0.0596 0.3217 1
Loa Loa (eye worm) DR-78 0.0281 0.1478 0.3166
Brugia malayi Protein kinase domain containing protein 0.0017 0.0019 0.004
Entamoeba histolytica protein kinase, putative 0.0035 0.0121 0.1448
Echinococcus granulosus g protein coupled receptor 0.0058 0.0247 0.029
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0039 0.0038
Echinococcus granulosus lamin 0.0061 0.0261 0.0307
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0247 0.029
Brugia malayi sulfakinin receptor protein 0.0058 0.0247 0.0528
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0047 0.0145
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0058 0.0247 0.029
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0142 0.0697
Trichomonas vaginalis aldehyde oxidase, putative 0.0809 0.4391 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0019 0.004
Schistosoma mansoni cpg binding protein 0.0068 0.0303 0.0357
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0049 0.0195 0.0229
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0596 0.3217 0.3785
Loa Loa (eye worm) hypothetical protein 0.0596 0.3217 0.6888
Onchocerca volvulus 0.0061 0.0261 0.0812
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.004 0.0147 0.0314
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.002 0.0039 0.0134
Onchocerca volvulus 0.0049 0.0195 0.0605
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0048 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0439 0.2351 0.5034
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0191 0.0224
Trichomonas vaginalis glucosylceramidase, putative 0.0381 0.2031 0.4626
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0023 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0083 0.0188
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0026 0.007 0.0242
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0047 0.023
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0216 0.0462
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0596 0.3217 0.3785
Trichomonas vaginalis helicase, putative 0.0015 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0156 0.0356
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.003 0.0093 0.0093
Leishmania major DNA polymerase kappa, putative 0.0021 0.0042 0.0045
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0022 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0083 0.0188
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.003 0.0093 0.0093
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.002 0.0039 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0596 0.3217 0.6888
Schistosoma mansoni lamin 0.0061 0.0261 0.0307
Loa Loa (eye worm) cytochrome P450 0.002 0.0039 0.0083
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0058 0.0247 0.0528
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0182 0.257
Schistosoma mansoni neuropeptide F-like receptor 0.0058 0.0247 0.029
Plasmodium vivax SET domain protein, putative 0.0036 0.0126 0.1865
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0142 0.2135
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0019 0.0019
Echinococcus multilocularis transcription factor Dp 1 0.0045 0.0172 0.0172
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0039 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0247 0.029
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0088 0.0103
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0052 0.0216 0.0254
Loa Loa (eye worm) neuropeptide F receptor 0.0058 0.0247 0.0528
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0859 0.467 1
Plasmodium falciparum ferredoxin, putative 0.0026 0.007 0.0866
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0077 0.0351 0.5662
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0015 0.0015
Leishmania major ferredoxin, 2fe-2s-like protein 0.0026 0.007 0.0105
Echinococcus multilocularis sex peptide receptor 0.0058 0.0247 0.0247
Loa Loa (eye worm) hypothetical protein 0.0036 0.0126 0.027
Onchocerca volvulus 0.0058 0.0247 0.0767
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0138 0.069 0.0812
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0106 0.0226
Loa Loa (eye worm) hypothetical protein 0.0596 0.3217 0.6888
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0042 0.0205
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0126 0.0149
Echinococcus multilocularis serotonin receptor 0.0058 0.0247 0.0247
Trypanosoma cruzi polyprenyl synthase, putative 0.003 0.0093 0.0155
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0809 0.4391 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0048 0.0191 0.0408
Giardia lamblia [2Fe-2S] ferredoxin 0.0026 0.007 0.0516
Echinococcus granulosus tyrosine protein kinase Src64B 0.0044 0.0169 0.0199
Echinococcus multilocularis thyroid hormone receptor alpha 0.0596 0.3217 0.3217
Plasmodium vivax ferredoxin, putative 0.0026 0.007 0.0866
Brugia malayi Carboxylesterase family protein 0.0079 0.0363 0.0777
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0048 0.0191 0.0224
Loa Loa (eye worm) neuropeptide F receptor 0.0058 0.0247 0.0528
Schistosoma mansoni cpg binding protein 0.0065 0.0283 0.0333
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Treponema pallidum hypothetical protein 0.0131 0.0652 0.4019
Loa Loa (eye worm) TK protein kinase 0.0035 0.0121 0.0259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0156 0.0356
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0015 0.0017
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0083 0.0385 0.0824
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0019 0.0032 0.0205
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0042 0.0077
Echinococcus granulosus neuropeptide FF receptor 2 0.0058 0.0247 0.029
Onchocerca volvulus 0.0058 0.0247 0.0767
Mycobacterium tuberculosis Conserved protein 0.0039 0.0142 0.0697
Echinococcus multilocularis G protein coupled receptor 139 0.0058 0.0247 0.0247
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0142 0.0491
Schistosoma mansoni nuclear hormone receptor 0.0281 0.1478 0.174
Brugia malayi Protein K4 0.0019 0.0032 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0023 0.0053
Loa Loa (eye worm) hypothetical protein 0.0101 0.0483 0.1034
Brugia malayi Intermediate filament tail domain containing protein 0.0061 0.0261 0.0559
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0077 0.0351 0.0753
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0596 0.3217 0.6888
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0022 0.0026
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0182 0.0348
Brugia malayi ORL1-like opioid receptor 0.0058 0.0247 0.0528
Loa Loa (eye worm) hypothetical protein 0.0028 0.0082 0.0175
Schistosoma mansoni hypothetical protein 0.0058 0.0247 0.029
Echinococcus multilocularis cpg binding protein 0.0068 0.0303 0.0303
Echinococcus multilocularis sodium and chloride dependent glycine 0.0048 0.0191 0.0191
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0026 0.007 0.0743
Echinococcus multilocularis FTZ F1 alpha 0.0596 0.3217 0.3217
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0154 0.0779 0.27
Schistosoma mansoni lozenge 0.006 0.0259 0.0304
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0162 0.0162
Schistosoma mansoni biogenic amine (5HT) receptor 0.0058 0.0247 0.029
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0126 0.16
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0596 0.3217 0.3785
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.002 0.0039 0.019
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.002 0.0039 0.019
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0403 0.2152 0.2532
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0282 0.1484 0.3177
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0596 0.3217 0.3785
Schistosoma mansoni tyrosine kinase 0.0044 0.0169 0.0199
Loa Loa (eye worm) CXXC zinc finger family protein 0.0065 0.0283 0.0606
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0247 0.0247
Mycobacterium ulcerans lipase LipD 0.0039 0.0142 0.0491
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0142 0.0322
Onchocerca volvulus 0.0048 0.0191 0.0593
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Echinococcus granulosus cpg binding protein 0.0068 0.0303 0.0357
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.0191 0.0224
Echinococcus granulosus FTZ F1 alpha 0.0596 0.3217 0.3785
Trypanosoma brucei unspecified product 0.0021 0.0042 0.0077
Schistosoma mansoni amine GPCR 0.0058 0.0247 0.029
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0042 0.0089
Loa Loa (eye worm) hypothetical protein 0.0048 0.0191 0.0408
Echinococcus granulosus hypothetical protein 0.0863 0.4692 0.5521
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0169 0.0199
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0042 0.0144
Schistosoma mansoni aldehyde dehydrogenase 0.0137 0.0681 0.0801
Loa Loa (eye worm) hypothetical protein 0.0079 0.0363 0.0777
Leishmania major hypothetical protein, conserved 0.0026 0.007 0.0105
Echinococcus granulosus peptide allatostatin:somatostatin 0.0058 0.0247 0.029
Echinococcus granulosus g protein coupled receptor 0.0058 0.0247 0.029
Schistosoma mansoni retinoic acid receptor RXR 0.0703 0.3807 0.4479
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0058 0.0247 0.029
Loa Loa (eye worm) G-protein coupled receptor 0.0058 0.0247 0.0528
Brugia malayi hypothetical protein 0.0058 0.0247 0.0528
Echinococcus multilocularis fmrfamide receptor 0.0058 0.0247 0.0247
Brugia malayi nuclear receptor RXR 0.0281 0.1478 0.3166
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0058 0.0247 0.0528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0142 0.0322
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0315 0.1665 0.1665
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0191 0.0224
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0048 0.0191 0.0408
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0041 0.0154 0.206
Onchocerca volvulus 0.0058 0.0247 0.0767
Echinococcus granulosus 7TM GPCR rhodopsin 0.0058 0.0247 0.029
Brugia malayi nuclear receptor NHR-67 0.0281 0.1478 0.3166
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0145 0.0145
Mycobacterium ulcerans hypothetical protein 0.0131 0.0652 0.2261
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.002 0.0023
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0058 0.0247 0.029
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0182 0.0415
Brugia malayi orphan nuclear receptor NR2E1 0.0281 0.1478 0.3166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0216 0.0491
Onchocerca volvulus 0.0039 0.0142 0.044
Brugia malayi SRC-1 0.0044 0.0169 0.0361
Loa Loa (eye worm) hypothetical protein 0.0079 0.0363 0.0777
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0581 0.3134 0.6712
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0681 0.236
Schistosoma mansoni polycystin 1-related 0.0043 0.0162 0.0191
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0058 0.0247 0.029
Brugia malayi hypothetical protein 0.0019 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0061 0.0261 0.0559
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0021 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0596 0.3217 0.6888
Onchocerca volvulus 0.0058 0.0247 0.0767
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0058 0.0247 0.0528
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0058 0.0247 0.0247
Trichomonas vaginalis Ferredoxin 4 0.0026 0.007 0.0159
Onchocerca volvulus Neuropeptide F receptor homolog 0.0058 0.0247 0.0767
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0038 0.0086
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.002 0.0039 0.0134
Brugia malayi hypothetical protein 0.0058 0.0247 0.0528
Brugia malayi photoreceptor-specific nuclear receptor 0.0596 0.3217 0.6888
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.012 0.0587 0.1336
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0182 0.0214
Loa Loa (eye worm) hypothetical protein 0.0048 0.0191 0.0408
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0058 0.0247 0.029
Trypanosoma cruzi polyprenyl synthase, putative 0.003 0.0093 0.0155
Schistosoma mansoni farnesyl pyrophosphate synthase 0.012 0.0587 0.069
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0019 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0075 0.0171
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0351 0.0741
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0021 0.0024
Brugia malayi Doublecortin family protein 0.0043 0.0162 0.0347
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0596 0.3217 0.6888
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0114 0.026
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0381 0.2031 0.7044
Echinococcus multilocularis somatostatin receptor 0.0058 0.0247 0.0247
Echinococcus granulosus Ankyrin 0.0017 0.002 0.0023
Brugia malayi hypothetical protein 0.0048 0.0191 0.0408
Trichomonas vaginalis glucosylceramidase, putative 0.0381 0.2031 0.4626
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0596 0.3217 0.6888
Loa Loa (eye worm) hypothetical protein 0.048 0.2575 0.5515
Brugia malayi Uncoordinated protein 44 0.0017 0.0019 0.004
Trypanosoma cruzi Emopamil binding protein, putative 0.016 0.0812 0.1702
Schistosoma mansoni phospholipase D 0.012 0.0589 0.0693
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0058 0.0247 0.029
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0058 0.0247 0.029
Loa Loa (eye worm) hypothetical protein 0.0596 0.3217 0.6888
Echinococcus multilocularis Ankyrin 0.0017 0.002 0.002
Schistosoma mansoni nuclear receptor nhr-48 0.0281 0.1478 0.174
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0061 0.0261 0.0559
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0381 0.2031 0.7044
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.0121 0.0142
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.002 0.0039 0.019
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0385 0.6429
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0058 0.0247 0.0247
Mycobacterium ulcerans oxidoreductase 0.0026 0.007 0.0242
Brugia malayi RE15519p 0.0058 0.0247 0.0528
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.024 0.125 0.4334
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0044 0.0169 0.0169
Loa Loa (eye worm) polyprenyl synthetase 0.003 0.0093 0.0199
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0042 0.0077
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.002 0.0039 0.0134
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0188 0.0962 0.1132
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0126 0.0126
Schistosoma mansoni growth hormone secretagogue receptor 0.0058 0.0247 0.029
Loa Loa (eye worm) hypothetical protein 0.0043 0.0162 0.0347
Echinococcus multilocularis ubiquitin specific protease 41 0.0046 0.0182 0.0182
Brugia malayi G protein-coupled receptor F59B2.13 0.0058 0.0247 0.0528
Echinococcus multilocularis dna polymerase eta 0.0021 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Echinococcus multilocularis serotonin receptor 0.0058 0.0247 0.0247
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0129 0.0639 0.2216
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0019 0.0059
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0044 0.0169 0.0169
Chlamydia trachomatis ferredoxin 0.0026 0.007 0.1063
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.003 0.0093 0.0187
Onchocerca volvulus 0.0058 0.0247 0.0767
Schistosoma mansoni opsin-like receptor 0.0058 0.0247 0.029
Loa Loa (eye worm) phospholipase D 0.0023 0.0051 0.011
Schistosoma mansoni neuropeptide f receptor 76f 0.0058 0.0247 0.029
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0016
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.012 0.0587 0.1336
Trypanosoma brucei cardiolipin synthetase, putative 0.0042 0.0157 0.0325
Echinococcus granulosus dna polymerase eta 0.0021 0.0042 0.0049
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0167 0.0197
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0182 0.0378
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Onchocerca volvulus Glucosylceramidase homolog 0.0381 0.2031 0.6314
Brugia malayi putative neuropeptide receptor 0.0058 0.0247 0.0528
Onchocerca volvulus 0.0058 0.0247 0.0767
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0089 0.1199
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.0191 0.0224
Echinococcus multilocularis tumor protein p63 0.076 0.4124 0.4124
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0042 0.0157 0.207
Echinococcus granulosus tumor protein p63 0.076 0.4124 0.4852
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0042 0.0077
Brugia malayi beta-lactamase family protein 0.0039 0.0142 0.0303
Echinococcus granulosus tm gpcr rhodopsin 0.0058 0.0247 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0247 0.029
Echinococcus granulosus cytochrome P450 2K1 0.002 0.0039 0.0045
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0097 0.0464 0.0546
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0058 0.0247 0.029
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.003 0.0093 0.157
Schistosoma mansoni neuropeptide receptor 0.0058 0.0247 0.029
Entamoeba histolytica hypothetical protein 0.0039 0.0141 0.1823
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0048 0.0191 0.0191
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0596 0.3217 0.3785
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0044 0.0169 0.0199
Echinococcus multilocularis tyrosine protein kinase Blk 0.004 0.0145 0.0145
Schistosoma mansoni neuropeptide receptor 0.0058 0.0247 0.029
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Onchocerca volvulus 0.011 0.0532 0.1654
Loa Loa (eye worm) norepinephrine transporter 0.0282 0.1484 0.3177
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0129 0.0639 0.3145
Brugia malayi Phospholipase d protein 1 0.012 0.0589 0.1261
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0281 0.1478 0.4596
Brugia malayi hypothetical protein 0.0058 0.0247 0.0528
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0662 0.3581 0.3581
Echinococcus granulosus neuropeptides capa receptor 0.0058 0.0247 0.029
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0596 0.3217 0.6888
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0042 0.0077
Toxoplasma gondii hypothetical protein 0.0048 0.0191 0.2575
Brugia malayi Carboxylesterase family protein 0.0079 0.0363 0.0777
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0142 0.0322
Schistosoma mansoni amine GPCR 0.0058 0.0247 0.029
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.012 0.0587 0.2889
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0859 0.467 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0023 0.005
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0042 0.0045
Toxoplasma gondii hypothetical protein 0.0048 0.0191 0.2575
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0075 0.0171
Echinococcus granulosus phospholipase d3 0.0023 0.0051 0.006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.002 0.0039 0.019
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.002 0.0039 0.019
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0162 0.2497
Trichomonas vaginalis Ferredoxin 1 0.0026 0.007 0.0159
Loa Loa (eye worm) hypothetical protein 0.0017 0.002 0.0042
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0021 0.0024
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0048 0.0191 0.0224
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0019 0.0032 0.0057
Loa Loa (eye worm) hypothetical protein 0.0315 0.1665 0.3564
Plasmodium vivax cardiolipin synthetase, putative 0.0019 0.0032 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0142 0.0322
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0681 0.236
Onchocerca volvulus 0.0065 0.0283 0.088
Echinococcus multilocularis g-protein coupled receptor 0.0058 0.0247 0.0247
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0247 0.0247
Trypanosoma cruzi cardiolipin synthetase, putative 0.0042 0.0157 0.0294
Loa Loa (eye worm) hypothetical protein 0.006 0.0255 0.0546
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0052 0.0216 0.045
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0041 0.0154 0.0331
Mycobacterium ulcerans endonuclease IV 0.0083 0.0385 0.1334
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0021 0.0021
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0058 0.0247 0.0528
Brugia malayi protein-tyrosine kinase 0.004 0.0145 0.0311
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0247 0.029
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0089 0.1199
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0596 0.3217 0.3785
Schistosoma mansoni neuropeptide receptor 0.0058 0.0247 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0247 0.029
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0126 0.0149
Loa Loa (eye worm) beta-lactamase 0.0039 0.0142 0.0303
Echinococcus granulosus sodium and chloride dependent glycine 0.0048 0.0191 0.0224
Trypanosoma brucei farnesyl pyrophosphate synthase 0.012 0.0587 0.1246
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0042 0.0077
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0191 0.0408
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.003 0.0093 0.1275
Trichomonas vaginalis glucosylceramidase, putative 0.0581 0.3134 0.7138
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0026 0.007 0.0866
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0026 0.007 0.0343
Schistosoma mansoni intermediate filament proteins 0.0061 0.0261 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0038 0.0086
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0137 0.0681 0.1419
Schistosoma mansoni hypothetical protein 0.0184 0.094 0.1106
Mycobacterium ulcerans hypothetical protein 0.0022 0.0047 0.0162
Schistosoma mansoni rab6-interacting 0.0043 0.0162 0.0191
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0041 0.0154 0.0287
Loa Loa (eye worm) hypothetical protein 0.0315 0.1665 0.3564
Onchocerca volvulus Bile acid receptor homolog 0.0596 0.3217 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0077 0.0351 0.0414
Loa Loa (eye worm) hypothetical protein 0.0282 0.1484 0.3177
Echinococcus granulosus acetylcholinesterase 0.0079 0.0363 0.0427
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Trypanosoma cruzi target of rapamycin kinase 3 0.0042 0.0157 0.0292
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0089 0.0146
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0596 0.3217 0.3785
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0142 0.0303
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.002 0.0039 0.0134
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.002 0.0039 0.019
Mycobacterium ulcerans beta-lactamase 0.0039 0.0142 0.0491
Trichomonas vaginalis glucosylceramidase, putative 0.0381 0.2031 0.4626
Schistosoma mansoni DNA polymerase eta 0.0021 0.0042 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0023 0.0053
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Onchocerca volvulus 0.0282 0.1484 0.4613
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0247 0.029
Echinococcus multilocularis sodium and chloride dependent glycine 0.0048 0.0191 0.0191
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0182 0.0415
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0021 0.0032
Brugia malayi hypothetical protein 0.011 0.0533 0.1141
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0016
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0044 0.0169 0.0169
Echinococcus multilocularis neuropeptides capa receptor 0.0058 0.0247 0.0247
Entamoeba histolytica phospholipase D, putative 0.012 0.0589 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0023 0.0053
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0042 0.0095
Brugia malayi Cytochrome P450 family protein 0.0065 0.0284 0.0609
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0058 0.0247 0.0528
Schistosoma mansoni thyroid hormone receptor 0.0596 0.3217 0.3785
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.007 0.0105
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0042 0.0077
Echinococcus multilocularis neuropeptide s receptor 0.0556 0.2998 0.2998
Loa Loa (eye worm) nuclear receptor NHR-67 0.0281 0.1478 0.3166
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0224 0.048
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0021 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0099 0.0226
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Echinococcus multilocularis orexin receptor type 2 0.0058 0.0247 0.0247
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0142 0.0697
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0042 0.0089
Brugia malayi nuclear receptor NHR-88 0.0596 0.3217 0.6888
Brugia malayi nuclear hormone receptor family member nhr-6 0.0281 0.1478 0.3166
Schistosoma mansoni opsin-like receptor 0.0058 0.0247 0.029
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.012 0.0587 1
Mycobacterium tuberculosis Conserved protein 0.0039 0.0142 0.0697
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Toxoplasma gondii endonuclease IV APN 0.0083 0.0385 0.5516
Trichomonas vaginalis Ferredoxin 7 0.0026 0.007 0.0159
Loa Loa (eye worm) solute carrier family 6 member 4 0.0282 0.1484 0.3177
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0058 0.0247 0.0247
Onchocerca volvulus 0.0048 0.0191 0.0593
Echinococcus granulosus ubiquitin specific protease 41 0.0046 0.0182 0.0214
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0247 0.0247
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0247 0.0247
Trypanosoma cruzi cytochrome P450, putative 0.004 0.0147 0.0272
Trichomonas vaginalis glucosylceramidase, putative 0.0381 0.2031 0.4626
Mycobacterium tuberculosis Conserved protein 0.0039 0.0142 0.0697
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0044 0.0094
Brugia malayi CHD4 protein 0.0016 0.0015 0.0032
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0596 0.3217 0.3785
Schistosoma mansoni amine GPCR 0.0445 0.238 0.2801
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0126 0.0149
Echinococcus multilocularis acetylcholinesterase 0.0079 0.0363 0.0363
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.0187
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0141 0.0166
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0097 0.0464 0.0546
Trichomonas vaginalis glucosylceramidase, putative 0.0581 0.3134 0.7138
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0046 0.0182 0.0214
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0026 0.007 0.0242
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0023 0.0027
Brugia malayi Nuclear hormone receptor-like 1 0.0315 0.1665 0.3564
Onchocerca volvulus 0.0058 0.0247 0.0767
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0083 0.0385 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0065 0.0284 0.0609
Leishmania major hypothetical protein, conserved 0.016 0.0812 0.1702
Loa Loa (eye worm) runx1 0.006 0.0259 0.0554
Plasmodium falciparum transporter, putative 0.0048 0.0191 0.3001
Trichomonas vaginalis esterase, putative 0.0039 0.0142 0.0322
Leishmania major hypothetical protein, conserved 0.0029 0.0089 0.0146
Leishmania major cytochrome p450-like protein 0.002 0.0039 0.0038
Brugia malayi Polyprenyl synthetase family protein 0.003 0.0093 0.0199
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0047 0.01
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.002 0.0039 0.019
Loa Loa (eye worm) hypothetical protein 0.0403 0.2152 0.4607
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.002 0.0039 0.019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0247 0.029
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0351 0.0711
Loa Loa (eye worm) hypothetical protein 0.0048 0.0191 0.0408
Loa Loa (eye worm) hypothetical protein 0.0048 0.0191 0.0408
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0058 0.0247 0.0528
Echinococcus multilocularis neuropeptides capa receptor 0.0058 0.0247 0.0247
Trypanosoma cruzi cytochrome P450, putative 0.004 0.0147 0.0272
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0021 0.0044
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0281 0.1478 0.1478
Echinococcus granulosus Nuclear hormone receptor HR96 0.0281 0.1478 0.174
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0142 0.0167
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0224 0.048
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0058 0.0247 0.0528
Loa Loa (eye worm) hypothetical protein 0.0039 0.0142 0.0303
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0281 0.1478 0.1478
Schistosoma mansoni RAR-like nuclear receptor 0.0596 0.3217 0.3785
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0019 0.004
Loa Loa (eye worm) polyprenyl synthetase 0.012 0.0587 0.1257
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.012 0.0587 0.1218
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0021 0.0021
Mycobacterium ulcerans oxygenase 0.0026 0.007 0.0242
Onchocerca volvulus 0.0058 0.0247 0.0767
Onchocerca volvulus 0.0058 0.0247 0.0767
Leishmania major cardiolipin synthetase, putative 0.0019 0.0032 0.0025
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.002 0.0039 0.0134
Loa Loa (eye worm) hypothetical protein 0.0029 0.0089 0.019
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.012 0.0587 1
Echinococcus multilocularis lamin 0.0061 0.0261 0.0261
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0809 0.4391 1
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0047 0.0237
Schistosoma mansoni adenoreceptor 0.0058 0.0247 0.029
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0052 0.0216 0.0419
Onchocerca volvulus 0.0058 0.0247 0.0767
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0315 0.1665 0.1959
Entamoeba histolytica phospholipase D, putative 0.012 0.0589 1
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0083 0.0385 0.1894
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0247 0.029
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0022 0.0047 0.01
Echinococcus multilocularis Protein lozenge 0.006 0.0259 0.0259
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0048 0.0191 0.0224
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0032 0.0073
Loa Loa (eye worm) hypothetical protein 0.0596 0.3217 0.6888
Treponema pallidum sodium- and chloride- dependent transporter 0.0282 0.1484 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0023 0.0006
Leishmania major lanosterol 14-alpha-demethylase, putative 0.002 0.0039 0.0038
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0089 0.1199
Loa Loa (eye worm) hypothetical protein 0.0039 0.0142 0.0303
Onchocerca volvulus 0.0058 0.0247 0.0767
Brugia malayi hypothetical protein 0.0058 0.0247 0.0528
Onchocerca volvulus 0.0281 0.1478 0.4596
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0042 0.0157 0.0323
Trypanosoma cruzi Emopamil binding protein, putative 0.016 0.0812 0.1702
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0058 0.0247 0.0767
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0097 0.0464 0.0546
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0596 0.3217 0.3217
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0142 0.0303
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0129 0.0639 0.0752
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0169 0.0169
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0596 0.3217 0.3217
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0042 0.0042
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0126 0.0126
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0129 0.0639 0.0639
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0041 0.0154 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0596 0.3217 0.6888
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0596 0.3217 0.6888
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0129 0.0639 0.1368
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0058 0.0247 0.0247
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0079 0.0363 0.0427
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0026 0.007 0.007
Schistosoma mansoni lamin 0.0061 0.0261 0.0307
Onchocerca volvulus 0.0058 0.0247 0.0767
Trypanosoma cruzi cytochrome p450-like protein, putative 0.002 0.0039 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.002 0.0039 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.0187
Chlamydia trachomatis endonuclease IV 0.0083 0.0385 1
Trichomonas vaginalis glucosylceramidase, putative 0.0381 0.2031 0.4626
Loa Loa (eye worm) hypothetical protein 0.0048 0.0191 0.0408
Echinococcus granulosus ecdysone induced protein 78C 0.0596 0.3217 0.3785
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0142 0.0167
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0273 0.1434 0.7058
Brugia malayi putative neuropeptide receptor NPR1 0.0058 0.0247 0.0528
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0247 0.0247
Echinococcus granulosus orexin receptor type 2 0.0058 0.0247 0.029
Brugia malayi Nuclear hormone receptor E75 0.0281 0.1478 0.3166
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0021 0.0044
Echinococcus granulosus dro:myosuppressin receptor 0.0058 0.0247 0.029
Brugia malayi hypothetical protein 0.0281 0.1478 0.3166
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0016
Schistosoma mansoni trans-prenyltransferase 0.003 0.0093 0.0109
Echinococcus multilocularis 0.002 0.0039 0.0039
Schistosoma mansoni nuclear receptor 0.0281 0.1478 0.174
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.012 0.0587 0.2035
Brugia malayi Phospholipase D. Active site motif family protein 0.0023 0.0051 0.011
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0859 0.467 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0281 0.1478 0.174
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0041 0.0154 0.2026
Schistosoma mansoni hypothetical protein 0.092 0.5008 0.5892
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0596 0.3217 0.6888
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Schistosoma mansoni thyroid hormone receptor 0.0596 0.3217 0.3785
Echinococcus multilocularis serotonin transporter 0.0282 0.1484 0.1484
Echinococcus granulosus fmrfamide receptor 0.0058 0.0247 0.029
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.002 0.0039 0.019
Echinococcus granulosus transcription factor Dp 1 0.0045 0.0172 0.0203
Brugia malayi Nuclear hormone receptor E75 0.0281 0.1478 0.3166
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0596 0.3217 0.6888
Loa Loa (eye worm) cytochrome P450 family protein 0.004 0.0147 0.0316
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0247 0.029
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0041 0.0154 0.0352
Leishmania major C-8 sterol isomerase-like protein 0.0859 0.467 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0099 0.0226
Brugia malayi nuclear hormone receptor family member odr-7 0.0281 0.1478 0.3166
Trichomonas vaginalis glucosylceramidase, putative 0.0581 0.3134 0.7138
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0111 0.0131
Schistosoma mansoni hypothetical protein 0.0058 0.0247 0.029
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.003 0.0093 0.0109
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0142 0.0491
Brugia malayi hypothetical protein 0.0039 0.0141 0.0303
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0077 0.0351 0.0711
Trichomonas vaginalis glucosylceramidase, putative 0.0402 0.2145 0.4884
Brugia malayi hypothetical protein 0.048 0.2575 0.5515
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0224 0.048
Loa Loa (eye worm) hypothetical protein 0.0111 0.0541 0.1158
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0052 0.0216 0.0419
Echinococcus granulosus death domain containing protein 0.0017 0.0019 0.0022
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0154 0.0779 0.27
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Schistosoma mansoni microtubule-associated protein tau 0.1553 0.8499 1
Brugia malayi Dopamine receptor protein 2 0.0058 0.0247 0.0528
Echinococcus multilocularis neuropeptide receptor 0.0058 0.0247 0.0247
Schistosoma mansoni loxhd1 0.0043 0.0162 0.0191
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.003 0.0093 0.0937
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0385 0.6429
Toxoplasma gondii ferredoxin, putative 0.0026 0.007 0.0743
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0137 0.0681 0.335
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0097 0.0464 0.0464
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0046 0.0182 0.258
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0315 0.1665 0.1959
Schistosoma mansoni cellular tumor antigen P53 0.0111 0.0541 0.0636
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0182 0.0214
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0191 0.0408
Trichomonas vaginalis Ferredoxin 6 0.0026 0.007 0.0159
Leishmania major DNA polymerase eta, putative 0.0021 0.0042 0.0045
Echinococcus granulosus neuropeptides capa receptor 0.0058 0.0247 0.029
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0596 0.3217 0.6888
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.002 0.0039 0.0134
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0281 0.1478 0.174
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0058 0.0247 0.029
Echinococcus granulosus tachykinin peptides receptor 99D 0.0058 0.0247 0.029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0596 0.3217 0.6888
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0021 0.0021
Plasmodium falciparum amino acid transporter, putative 0.0048 0.0191 0.3001
Brugia malayi hypothetical protein 0.0315 0.1665 0.3564
Brugia malayi hypothetical protein 0.0058 0.0247 0.0528
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0596 0.3217 0.6888
Schistosoma mansoni neuropeptide receptor 0.0058 0.0247 0.029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.0187
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0026 0.007 0.0137
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0042 0.0095
Schistosoma mansoni hypothetical protein 0.0184 0.094 0.1106
Brugia malayi larval opioid receptor 0.0058 0.0247 0.0528
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0101 0.0483 0.8061
Schistosoma mansoni rab6-interacting 0.0043 0.0162 0.0191
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0182 0.0182
Schistosoma mansoni cpg binding protein 0.0068 0.0303 0.0357
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0075 0.0171
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Loa Loa (eye worm) hypothetical protein 0.0596 0.3217 0.6888
Brugia malayi hypothetical protein 0.0029 0.0089 0.019
Brugia malayi AKH receptor 0.0058 0.0247 0.0528
Brugia malayi M-phase phosphoprotein, mpp8 0.011 0.0532 0.1139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0048 0.0191 0.0408
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0388 0.2068 0.2068
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Loa Loa (eye worm) hypothetical protein 0.0029 0.0088 0.0188
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0041 0.0154 0.0352
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.002 0.0039 0.019
Echinococcus granulosus microtubule associated protein 2 0.1553 0.8499 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0247 0.0247
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0247 0.029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0182 0.0415
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.003 0.0093 1
Echinococcus granulosus lamin dm0 0.0061 0.0261 0.0307
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0042 0.0045
Loa Loa (eye worm) hypothetical protein 0.0596 0.3217 0.6888
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.004 0.0147 0.0147
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0019 0.0032 0.0038
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0058 0.0247 0.0247
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.0138 0.0163
Echinococcus granulosus farnesyl pyrophosphate synthase 0.012 0.0587 0.069
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0058 0.0247 0.029
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0596 0.3217 0.3217
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0044 0.0169 0.0199
Onchocerca volvulus 0.0058 0.0247 0.0767
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0281 0.1478 0.4596
Echinococcus granulosus neuropeptide s receptor 0.0556 0.2998 0.3528
Echinococcus multilocularis allatostatin A receptor 0.0058 0.0247 0.0247
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0247 0.0247
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.0121 0.0121
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0141 0.0141
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0273 0.1434 0.4971
Brugia malayi tailless protein 0.0281 0.1478 0.3166
Trichomonas vaginalis glucosylceramidase, putative 0.0381 0.2031 0.4626
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.002 0.0039 0.019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0596 0.3217 0.6888
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.012 0.0591 0.1265
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Schistosoma mansoni hypothetical protein 0.0058 0.0247 0.029
Brugia malayi GnHR receptor homolog 0.0058 0.0247 0.0528
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Trypanosoma brucei C-8 sterol isomerase, putative 0.0859 0.467 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.004 0.0145 0.0145
Echinococcus multilocularis fmrfamide receptor 0.0058 0.0247 0.0247
Brugia malayi Pre-SET motif family protein 0.0036 0.0126 0.027
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0041 0.0154 0.2361
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0162 0.0191
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0191 0.2575
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0042 0.0045
Echinococcus multilocularis phospholipase D1 0.012 0.0589 0.0589
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Giardia lamblia Farnesyl diphosphate synthase 0.012 0.0587 1
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0052 0.0216 0.3181
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0075 0.0171
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.003 0.0093 0.0457
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0173 0.0395
Schistosoma mansoni biogenic amine receptor 0.0058 0.0247 0.029
Loa Loa (eye worm) hypothetical protein 0.0315 0.1665 0.3564
Echinococcus multilocularis conserved hypothetical protein 0.0805 0.4372 0.4372
Loa Loa (eye worm) hypothetical protein 0.0281 0.1478 0.3166
Echinococcus granulosus GPCR family 2 0.0017 0.0021 0.0024
Schistosoma mansoni biogenic amine receptor 0.0058 0.0247 0.029
Entamoeba histolytica hypothetical protein 0.0039 0.0141 0.1823
Echinococcus granulosus neuropeptide Y receptor 0.0058 0.0247 0.029
Echinococcus granulosus tyrosine protein kinase Blk 0.004 0.0145 0.0171
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0191 0.2575
Onchocerca volvulus 0.0039 0.0142 0.044
Echinococcus granulosus neuropeptide receptor A26 0.0556 0.2998 0.3528
Loa Loa (eye worm) hypothetical protein 0.0023 0.0051 0.011
Schistosoma mansoni neuropeptide F-like receptor 0.0058 0.0247 0.029
Loa Loa (eye worm) serotonin transporter b 0.0282 0.1484 0.3177
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0023 0.0051 0.0066
Brugia malayi hypothetical protein 0.0058 0.0247 0.0528
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0596 0.3217 0.6888
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0052 0.0216 0.0419
Brugia malayi nuclear hormone receptor 0.0281 0.1478 0.3166
Schistosoma mansoni tyrosine kinase 0.0044 0.0169 0.0199
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0026 0.007 0.0105
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0077 0.0351 0.0351
Echinococcus multilocularis phospholipase D 0.0106 0.0512 0.0512
Echinococcus granulosus tyrosine protein kinase Lyn 0.0044 0.0169 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0216 0.0491
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0137 0.0681 0.0801
Brugia malayi neuropeptide F receptor 0.0058 0.0247 0.0528
Brugia malayi beta-lactamase family protein 0.0039 0.0142 0.0303
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0015 0.0032
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0052 0.0216 0.045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0142 0.0322
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.016 0.0812 0.1702
Brugia malayi Cytochrome P450 family protein 0.004 0.0147 0.0316
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0047 0.0162
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.002 0.0039 0.019
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0048 0.0191 0.0191
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0129 0.0639 0.2216
Loa Loa (eye worm) G-protein coupled receptor 0.0058 0.0247 0.0528
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0042 0.0077
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0023 0.0027
Echinococcus granulosus neuropeptide receptor 0.0058 0.0247 0.029
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0042 0.0077
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0042 0.0157 0.0292
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0188 0.0962 0.0962
Brugia malayi steroid hormone receptor 0.0596 0.3217 0.6888
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.002 0.0039 0.0134
Echinococcus granulosus neuropeptide receptor 0.0058 0.0247 0.029
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0042 0.0077
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0402 0.2145 0.4884
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0142 0.0322
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.003 0.0093 0.0093
Loa Loa (eye worm) acetylcholinesterase 1 0.0079 0.0363 0.0777
Loa Loa (eye worm) hypothetical protein 0.0043 0.0162 0.0347
Loa Loa (eye worm) hypothetical protein 0.011 0.0533 0.1141
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.003 0.0093 0.0155
Loa Loa (eye worm) hypothetical protein 0.0078 0.0358 0.0766
Loa Loa (eye worm) melatonin receptor type 1A 0.0058 0.0247 0.0528
Loa Loa (eye worm) steroid hormone receptor 0.0596 0.3217 0.6888
Onchocerca volvulus Putative phospholipase D 0.0023 0.0051 0.0159
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0058 0.0247 0.0247
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0281 0.1478 0.1478
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0191 0.2575
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0142 0.0697
Loa Loa (eye worm) hypothetical protein 0.0058 0.0247 0.0528
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.003 0.0093 0.1094
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0169 0.0169

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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