Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0011 | 0.022 | 0.8987 |
Loa Loa (eye worm) | carboxylesterase | 0.0066 | 0.3946 | 0.3815 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0011 | 0.022 | 0.8987 |
Onchocerca volvulus | 0.0011 | 0.0245 | 0.0025 | |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0011 | 0.022 | 0.0557 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0011 | 0.0245 | 0.062 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0011 | 0.022 | 0.0557 |
Chlamydia trachomatis | ABC transporter ATP binding protein/permease | 0.0011 | 0.022 | 0.5 |
Onchocerca volvulus | 0.0011 | 0.0245 | 0.0025 | |
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0245 | 0.0025 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0011 | 0.022 | 0.8987 |
Echinococcus granulosus | 5'partial|ATP binding cassette sub family B | 0.0011 | 0.0212 | 0.0537 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0011 | 0.022 | 0.8987 |
Trichomonas vaginalis | abcb9, putative | 0.0011 | 0.022 | 0.8987 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0011 | 0.0245 | 0.062 |
Onchocerca volvulus | 0.0011 | 0.0245 | 0.0025 | |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0011 | 0.022 | 0.8987 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0011 | 0.022 | 0.0557 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0011 | 0.022 | 0.0557 |
Loa Loa (eye worm) | multidrug resistance protein 3 | 0.0011 | 0.022 | 0.0008 |
Entamoeba histolytica | P-glycoprotein-1 | 0.0011 | 0.022 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0011 | 0.0245 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.022 | 0.0008 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0011 | 0.022 | 0.8987 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0011 | 0.022 | 0.8987 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0011 | 0.022 | 0.0557 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0245 | 0.0033 |
Trichomonas vaginalis | abcb9, putative | 0.0011 | 0.022 | 0.8987 |
Toxoplasma gondii | ABC transporter transmembrane region domain-containing protein | 0.0011 | 0.022 | 0.5 |
Plasmodium falciparum | multidrug resistance protein 1 | 0.0011 | 0.022 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 0.3946 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 0.3946 | 1 |
Trichomonas vaginalis | ABC transporter, putative | 0.0011 | 0.022 | 0.8987 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0011 | 0.022 | 0.0557 |
Trichomonas vaginalis | taga, putative | 0.0011 | 0.022 | 0.8987 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.3946 | 0.3815 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0066 | 0.3946 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0011 | 0.0245 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0011 | 0.0245 | 0.0066 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0011 | 0.022 | 0.8987 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0011 | 0.022 | 0.8987 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0011 | 0.0245 | 0.5 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0011 | 0.0245 | 0.062 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0011 | 0.0245 | 0.062 |
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0245 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 1 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0011 | 0.022 | 0.8987 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0245 | 0.0025 |
Brugia malayi | Carboxylesterase family protein | 0.0066 | 0.3946 | 0.381 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0011 | 0.022 | 0.8987 |
Echinococcus multilocularis | ATP binding cassette sub family B | 0.0011 | 0.0212 | 0.0537 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0011 | 0.022 | 0.8987 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0011 | 0.022 | 0.8987 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0011 | 0.0245 | 0.062 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0011 | 0.0245 | 0.0066 |
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0245 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.3946 | 0.3815 |
Echinococcus multilocularis | neuroligin | 0.0011 | 0.0245 | 0.062 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0011 | 0.022 | 0.0557 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0011 | 0.0245 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.022 | 0.0008 |
Trichomonas vaginalis | ABC transporter, putative | 0.0011 | 0.022 | 0.8987 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0245 | 0.0033 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0011 | 0.022 | 0.0557 |
Trichomonas vaginalis | abcb9, putative | 0.0011 | 0.022 | 0.8987 |
Trichomonas vaginalis | ABC transporter, putative | 0.0011 | 0.022 | 0.8987 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0011 | 0.0245 | 0.0066 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0011 | 0.022 | 0.8987 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0011 | 0.022 | 0.8987 |
Entamoeba histolytica | P-glycoprotein 5, putative | 0.0011 | 0.022 | 0.5 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0011 | 0.022 | 0.0557 |
Toxoplasma gondii | ATP-binding cassette transporter ABC.B1 | 0.0011 | 0.022 | 0.5 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0011 | 0.022 | 0.0557 |
Entamoeba histolytica | P-glycoprotein-2 | 0.0011 | 0.022 | 0.5 |
Trichomonas vaginalis | ABC transporter, putative | 0.0011 | 0.022 | 0.8987 |
Leishmania major | p-glycoprotein | 0.0011 | 0.022 | 0.5 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0011 | 0.022 | 0.8987 |
Onchocerca volvulus | 0.0011 | 0.0245 | 0.0025 | |
Entamoeba histolytica | P-glycoprotein-5 | 0.0011 | 0.022 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0245 | 0.0033 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0011 | 0.0245 | 0.0066 |
Loa Loa (eye worm) | carboxylesterase | 0.0011 | 0.0245 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0245 | 0.0033 |
Schistosoma mansoni | gliotactin | 0.0011 | 0.0245 | 0.0066 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0011 | 0.022 | 0.8987 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0245 | 0.0033 |
Loa Loa (eye worm) | carboxylesterase | 0.0011 | 0.0245 | 0.0033 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0011 | 0.0245 | 1 |
Onchocerca volvulus | 0.0155 | 1 | 1 | |
Leishmania major | ATP-binding cassette protein subfamily B, member 2, putative | 0.0011 | 0.022 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0011 | 0.0245 | 0.062 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0011 | 0.0245 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0011 | 0.022 | 0.8987 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0011 | 0.022 | 0.0557 |
Plasmodium vivax | multidrug resistance protein 1, putative | 0.0011 | 0.022 | 0.5 |
Entamoeba histolytica | P-glycoprotein-2 | 0.0011 | 0.022 | 0.5 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0011 | 0.022 | 0.8987 |
Loa Loa (eye worm) | ATP-binding cassette sub-family B member 2 | 0.0011 | 0.022 | 0.0008 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0011 | 0.022 | 0.0557 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0066 | 0.3946 | 0.3815 |
Onchocerca volvulus | 0.0011 | 0.0245 | 0.0025 | |
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0245 | 0.0025 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0011 | 0.022 | 0.8987 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0011 | 0.022 | 0.0557 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0011 | 0.0245 | 0.0066 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0011 | 0.0245 | 1 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0011 | 0.022 | 0.8987 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0011 | 0.0245 | 0.062 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0245 | 0.0033 |
Entamoeba histolytica | P-glycoprotein-2, putative | 0.0011 | 0.022 | 0.5 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0011 | 0.022 | 0.0557 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0011 | 0.022 | 0.8987 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0245 | 0.0033 |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 0.3946 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0066 | 0.3946 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0066 | 0.3946 | 1 |
Entamoeba histolytica | P-glyco protein 6, putative | 0.0011 | 0.022 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0066 | 0.3946 | 0.381 |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 0.3946 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.