Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | steroid hormone receptor | 0.001 | 0.0069 | 0.0155 |
Mycobacterium ulcerans | monophosphatase CysQ | 0.0008 | 0.0037 | 0.0085 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0206 | 0.137 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | oxidoreductase | 0.0007 | 0.003 | 0.0067 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0069 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.003 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0434 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0112 | 0.1502 | 0.4486 |
Echinococcus multilocularis | tar DNA binding protein | 0.0261 | 0.3599 | 0.8101 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0147 | 0.1996 | 0.5546 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0112 | 0.1502 | 0.4486 |
Echinococcus granulosus | smad | 0.0009 | 0.0049 | 0.011 |
Echinococcus multilocularis | muscleblind protein | 0.0321 | 0.4442 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0007 | 0.0024 | 0.0055 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0007 | 0.003 | 0.0034 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0009 | 0.0046 | 0.003 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0156 | 0.1158 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0069 | 0.0155 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0112 | 0.1502 | 1 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0007 | 0.003 | 0.0036 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0156 | 0.1158 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0112 | 0.1502 | 0.1489 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0069 | 0.0155 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.003 | 0.0036 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0068 | 0.0887 | 0.0873 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0012 | 0.0095 | 0.0213 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0069 | 0.0155 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.0283 | 0.1624 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0037 | 0.0084 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0069 | 0.0191 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.003 | 0.0067 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0007 | 0.003 | 0.0036 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.0483 | 0.4672 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.0534 | 0.3447 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0294 | 0.0662 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.0283 | 0.1753 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0069 | 0.0191 |
Brugia malayi | RNA binding protein | 0.0261 | 0.3599 | 0.8101 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0016 | 0.0156 | 0.7645 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.3599 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0007 | 0.0024 | 0.0055 |
Trichomonas vaginalis | set domain proteins, putative | 0.0241 | 0.3319 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0069 | 0.0155 |
Onchocerca volvulus | 0.0031 | 0.0359 | 0.1001 | |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0193 | 0.2893 |
Schistosoma mansoni | hypothetical protein | 0.0008 | 0.0037 | 0.0103 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.3599 | 1 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0069 | 0.0155 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.0593 | 0.0578 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0359 | 0.0809 |
Brugia malayi | Inositol-1 | 0.0076 | 0.0999 | 0.225 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0112 | 0.1502 | 1 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0001 | 0.0002 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0048 | 0.0108 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0112 | 0.1502 | 0.1489 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0007 | 0.0024 | 0.0009 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0108 | 0.1449 | 0.1436 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.012 | 0.1619 | 1 |
Onchocerca volvulus | 0.0241 | 0.3319 | 1 | |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0016 | 0.0156 | 0.0891 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0069 | 0.0155 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0069 | 0.0155 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0178 | 0.0163 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.0049 | 0.011 |
Trypanosoma brucei | inositol polyphosphate 1-phosphatase, putative | 0.0008 | 0.0037 | 0.0085 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0156 | 0.1037 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.0593 | 0.3847 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.0049 | 0.011 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0007 | 0.003 | 0.0015 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0112 | 0.1502 | 1 |
Loa Loa (eye worm) | acetyltransferase | 0.0147 | 0.1996 | 0.4492 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0152 | 0.2066 | 0.4651 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0007 | 0.003 | 0.0034 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0007 | 0.003 | 0.0036 |
Brugia malayi | cytochrome P450 | 0.0007 | 0.0024 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.4442 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0361 | 0.0812 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0112 | 0.1502 | 0.4486 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.0283 | 0.2615 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0069 | 0.0155 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0361 | 0.2399 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0361 | 0.0812 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0007 | 0.003 | 0.0036 |
Echinococcus multilocularis | smad | 0.0009 | 0.0049 | 0.011 |
Echinococcus multilocularis | inositol monophosphatase | 0.0008 | 0.0037 | 0.0084 |
Trichomonas vaginalis | esterase, putative | 0.0112 | 0.1502 | 0.4486 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0076 | 0.0999 | 0.2962 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0049 | 0.011 |
Plasmodium vivax | hypothetical protein, conserved | 0.0112 | 0.1502 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0069 | 0.0155 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0359 | 0.0809 |
Mycobacterium tuberculosis | Conserved protein | 0.0112 | 0.1502 | 0.1489 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0069 | 0.0155 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0602 | 0.1355 |
Trypanosoma cruzi | myo-inositol-1 phosphatase, putative | 0.0008 | 0.0037 | 0.0085 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.003 | 0.0067 |
Echinococcus granulosus | 3'2'5' bisphosphate nucleotidase 1 | 0.0008 | 0.0037 | 0.0084 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0623 | 0.1732 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0005 | 0.0001 | 0.0002 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.013 | 0.1748 | 0.3935 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0007 | 0.003 | 0.0036 |
Trypanosoma cruzi | inositol polyphosphate 1-phosphatase, putative | 0.0008 | 0.0037 | 0.0085 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0069 | 0.0155 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0012 | 0.0095 | 0.0213 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0384 | 0.0864 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0156 | 0.0891 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0069 | 0.0155 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0283 | 0.1753 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0156 | 0.0891 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0008 | 0.0037 | 0.0043 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0206 | 0.0555 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.0593 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0434 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0007 | 0.0024 | 0.0009 |
Mycobacterium tuberculosis | Probable monophosphatase | 0.0008 | 0.0037 | 0.0022 |
Mycobacterium leprae | conserved hypothetical protein | 0.0112 | 0.1502 | 0.9264 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0076 | 0.0999 | 0.225 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0361 | 0.0812 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0602 | 0.1673 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.003 | 0.0036 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0048 | 0.0602 | 0.1355 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0156 | 0.1037 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0069 | 0.0155 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0112 | 0.1502 | 0.338 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0007 | 0.003 | 0.0067 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0156 | 0.0891 |
Echinococcus multilocularis | 0.0007 | 0.0024 | 0.0055 | |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0016 | 0.0156 | 0.0891 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.3599 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0108 | 0.1449 | 0.1436 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0007 | 0.003 | 0.0036 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0156 | 0.0891 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0076 | 0.0999 | 0.225 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0069 | 0.0155 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0001 | 0.0002 |
Brugia malayi | nuclear receptor RXR | 0.0005 | 0.0001 | 0.0002 |
Mycobacterium ulcerans | inositol-monophosphatase ImpA | 0.0008 | 0.0037 | 0.0085 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0112 | 0.1502 | 1 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.0534 | 0.1549 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0016 | 0.0156 | 0.0891 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.012 | 0.1619 | 0.1606 |
Mycobacterium ulcerans | beta-lactamase | 0.0112 | 0.1502 | 1 |
Schistosoma mansoni | cytochrome P450 | 0.0007 | 0.0024 | 0.0068 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0009 | 0.0048 | 0.0108 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0049 | 0.011 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0623 | 0.1403 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0206 | 0.1229 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.0593 | 0.1334 |
Leishmania major | inositol polyphosphate 1-phosphatase, putative | 0.0008 | 0.0037 | 0.0085 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0206 | 0.0464 |
Mycobacterium tuberculosis | Monophosphatase CysQ | 0.0008 | 0.0037 | 0.0022 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0112 | 0.1502 | 0.1489 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0005 | 0.0001 | 0.0002 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | RNA binding protein | 0.0261 | 0.3599 | 0.8101 |
Onchocerca volvulus | 0.0031 | 0.0361 | 0.1005 | |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0384 | 0.0864 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0009 | 0.0046 | 0.0143 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0206 | 0.379 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.0534 | 0.1201 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0602 | 0.1355 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0108 | 0.1449 | 0.1436 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0007 | 0.0024 | 0.0009 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0206 | 0.1229 |
Schistosoma mansoni | hypothetical protein | 0.0008 | 0.0037 | 0.0103 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0007 | 0.0024 | 0.0009 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0076 | 0.0999 | 0.6601 |
Echinococcus multilocularis | ferritin | 0.0009 | 0.0046 | 0.0103 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0007 | 0.0024 | 0.0009 |
Schistosoma mansoni | pap-inositol-14-phosphatase | 0.0008 | 0.0037 | 0.0103 |
Mycobacterium tuberculosis | Probable reductase | 0.0108 | 0.1449 | 0.1436 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0156 | 0.0891 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0069 | 0.0155 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0156 | 0.0351 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0069 | 0.0155 |
Mycobacterium leprae | Probable lipase LipE | 0.0112 | 0.1502 | 0.9264 |
Loa Loa (eye worm) | histone methyltransferase | 0.0011 | 0.0075 | 0.0168 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0069 | 0.0191 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0156 | 0.0891 |
Loa Loa (eye worm) | cytochrome P450 | 0.0007 | 0.0024 | 0.0055 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0361 | 0.1002 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.0534 | 0.1549 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0069 | 0.0191 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0156 | 0.0891 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.0593 | 0.3847 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0156 | 0.0351 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0156 | 0.0891 |
Brugia malayi | Pre-SET motif family protein | 0.0212 | 0.2908 | 0.6546 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0007 | 0.0024 | 0.0009 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0008 | 0.0037 | 0.0043 |
Schistosoma mansoni | ferritin light chain | 0.0009 | 0.0046 | 0.0127 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0335 | 0.0755 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0206 | 0.0555 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0283 | 0.1753 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0069 | 0.0155 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0384 | 0.1067 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.1389 | 0.3126 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0112 | 0.1502 | 0.4172 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0007 | 0.0024 | 0.0009 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0007 | 0.0024 | 0.0009 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.0283 | 0.1624 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.003 | 0.0067 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0361 | 0.1002 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0075 | 0.0168 |
Leishmania major | hypothetical protein, conserved | 0.0112 | 0.1502 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0206 | 0.1229 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0108 | 0.1449 | 0.1436 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0048 | 0.0602 | 0.1355 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0602 | 0.1673 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.3599 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0049 | 0.0135 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0283 | 0.2615 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0283 | 0.0638 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0156 | 0.2242 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.003 | 0.0015 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0206 | 0.0464 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0283 | 0.1753 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0152 | 0.2066 | 0.4651 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.1502 | 0.338 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0069 | 0.0155 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.0593 | 0.3946 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0212 | 0.2908 | 0.6546 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0206 | 0.0573 |
Brugia malayi | Smad1 | 0.0009 | 0.0049 | 0.011 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0069 | 0.0191 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0206 | 0.0464 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.0593 | 0.1334 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0384 | 0.1067 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0049 | 0.011 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0069 | 0.0155 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0068 | 0.0887 | 0.5408 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.0483 | 0.8048 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.0283 | 0.0269 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.003 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0283 | 0.0638 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0001 | 0.0002 |
Onchocerca volvulus | 0.0112 | 0.1502 | 0.4474 | |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.0049 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0069 | 0.0155 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0007 | 0.003 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0037 | 0.0084 |
Schistosoma mansoni | inositol monophosphatase | 0.0076 | 0.0999 | 0.2777 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0108 | 0.1449 | 0.1436 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0143 | 0.1938 | 0.4362 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0001 | 0.0002 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0602 | 0.1355 |
Leishmania major | trypanothione reductase | 0.0047 | 0.0593 | 0.3847 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.0283 | 0.1753 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0007 | 0.003 | 0.0036 |
Echinococcus multilocularis | GPCR, family 2 | 0.0048 | 0.0602 | 0.1355 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0112 | 0.1502 | 0.338 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0007 | 0.0024 | 0.0009 |
Echinococcus granulosus | muscleblind protein | 0.0321 | 0.4442 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0112 | 0.1502 | 0.1489 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.003 | 0.0036 |
Mycobacterium ulcerans | monophosphatase CysQ | 0.0008 | 0.0037 | 0.0085 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0359 | 0.0998 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0076 | 0.0999 | 0.6601 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0069 | 0.0155 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.003 | 0.0067 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0206 | 0.1229 |
Schistosoma mansoni | hypothetical protein | 0.0104 | 0.1389 | 0.3858 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0361 | 0.2275 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.003 | 0.0015 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.003 | 0.0021 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0206 | 0.0191 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.0593 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0076 | 0.0999 | 0.2962 |
Echinococcus granulosus | expressed protein | 0.0009 | 0.0046 | 0.0103 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0007 | 0.0024 | 0.0009 |
Brugia malayi | beta-lactamase family protein | 0.0112 | 0.1502 | 0.338 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0006 | 0.0003 | 0.0007 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0623 | 0.1403 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0007 | 0.0024 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.1502 | 0.338 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.0049 | 0.011 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0321 | 0.4442 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0075 | 0.0168 |
Brugia malayi | TAR-binding protein | 0.0261 | 0.3599 | 0.8101 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0007 | 0.0024 | 0.0009 |
Brugia malayi | Cytochrome P450 family protein | 0.0007 | 0.0024 | 0.0055 |
Schistosoma mansoni | tar DNA-binding protein | 0.0261 | 0.3599 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0112 | 0.1502 | 0.338 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0623 | 0.1732 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0261 | 0.3599 | 0.8101 |
Brugia malayi | Inositol monophosphatase family protein | 0.0008 | 0.0037 | 0.0084 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0019 | 0.0193 | 0.1139 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0283 | 0.0638 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0434 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0112 | 0.1502 | 0.338 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0007 | 0.003 | 0.0083 |
Mycobacterium tuberculosis | Conserved protein | 0.0112 | 0.1502 | 0.1489 |
Mycobacterium tuberculosis | Conserved protein | 0.0112 | 0.1502 | 0.1489 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0007 | 0.003 | 0.0036 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0147 | 0.1996 | 0.4492 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0069 | 0.0155 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0283 | 0.1753 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0206 | 0.313 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0178 | 0.0163 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0261 | 0.3599 | 0.8101 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0112 | 0.1502 | 0.1489 |
Toxoplasma gondii | hypothetical protein | 0.0008 | 0.0037 | 0.0085 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0007 | 0.003 | 0.0196 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.1502 | 0.338 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0007 | 0.003 | 0.0067 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.003 | 0.0036 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0069 | 0.0155 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.0049 | 0.0135 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0602 | 0.1673 |
Mycobacterium ulcerans | monophosphatase | 0.0008 | 0.0037 | 0.0085 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.003 | 0.0036 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0049 | 0.011 |
Onchocerca volvulus | 0.0112 | 0.1502 | 0.4474 | |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0076 | 0.0999 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0156 | 0.2242 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0049 | 0.011 |
Echinococcus granulosus | ferritin | 0.0009 | 0.0046 | 0.0103 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0156 | 0.0434 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0049 | 0.0135 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0156 | 0.6883 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0009 | 0.0046 | 0.0143 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0069 | 0.0155 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0206 | 0.1229 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0069 | 0.0155 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0076 | 0.0999 | 0.6601 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0007 | 0.003 | 0.0015 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0008 | 0.0037 | 0.0043 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0046 | 0.0127 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0283 | 0.1753 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0009 | 0.0046 | 0.003 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.0534 | 0.3552 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0602 | 0.1673 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0206 | 0.0464 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0112 | 0.1502 | 0.1489 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0046 | 0.0127 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0623 | 0.1732 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0007 | 0.0024 | 0.0009 |
Echinococcus multilocularis | 3'(2'),5' bisphosphate nucleotidase 1 | 0.0008 | 0.0037 | 0.0084 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0009 | 0.0048 | 0.0108 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0076 | 0.0999 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0007 | 0.0024 | 0.0009 |
Toxoplasma gondii | ABC1 family protein | 0.0112 | 0.1502 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0112 | 0.1502 | 0.4486 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0156 | 0.0891 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0069 | 0.0155 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0156 | 0.0891 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0007 | 0.003 | 0.0015 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0007 | 0.0024 | 0.0009 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.0049 | 0.0135 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0069 | 0.0155 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0069 | 0.0191 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.003 | 0.0036 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0005 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.0593 | 0.1334 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0007 | 0.0024 | 0.0009 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0156 | 0.2242 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0069 | 0.0155 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.003 | 0.0036 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0069 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0069 | 0.0155 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0623 | 0.1403 |
Schistosoma mansoni | apoferritin-2 | 0.0009 | 0.0046 | 0.0127 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.0534 | 0.3447 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0147 | 0.1996 | 0.4492 |
Echinococcus granulosus | GPCR family 2 | 0.0048 | 0.0602 | 0.1355 |
Entamoeba histolytica | 3(2),5-bisphosphate nucleotidase, putative | 0.0008 | 0.0037 | 0.0075 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.0283 | 0.0269 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0007 | 0.0024 | 0.0009 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0069 | 0.0155 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0007 | 0.003 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.1502 | 0.338 |
Echinococcus granulosus | tar DNA binding protein | 0.0261 | 0.3599 | 0.8101 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0602 | 0.1355 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0007 | 0.003 | 0.0015 |
Mycobacterium leprae | POSSIBLE MONOPHOSPHATASE CYSQ | 0.0008 | 0.0037 | 0.0079 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.012 | 0.1619 | 0.1606 |
Onchocerca volvulus | Inositol monophosphatase 3 homolog | 0.0008 | 0.0037 | 0.0022 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.0593 | 0.1334 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0283 | 0.1753 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0156 | 0.0351 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0016 | 0.0156 | 0.0891 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0007 | 0.003 | 0.0036 |
Mycobacterium ulcerans | hypothetical protein | 0.0112 | 0.1502 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0178 | 0.0163 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0069 | 0.0155 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0156 | 0.2242 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.0049 | 0.011 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0069 | 0.0119 |
Entamoeba histolytica | 3(2),5-bisphosphate nucleotidase, putative | 0.0008 | 0.0037 | 0.0075 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase, putative | 0.0008 | 0.0037 | 0.0085 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.0483 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0261 | 0.3599 | 0.8101 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0016 | 0.0156 | 0.0141 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0069 | 0.0191 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0011 | 0.0073 | 0.0164 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0108 | 0.1449 | 0.8933 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0076 | 0.0999 | 0.6601 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0076 | 0.0999 | 0.6601 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0007 | 0.003 | 0.0067 |
Brugia malayi | glutathione reductase | 0.0047 | 0.0593 | 0.1334 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0007 | 0.0024 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0069 | 0.0155 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0016 | 0.0156 | 0.0891 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0016 | 0.0156 | 0.0891 |
Echinococcus multilocularis | expressed protein | 0.0009 | 0.0046 | 0.0103 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0156 | 0.0891 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.003 | 0.0036 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.003 | 0.0015 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0112 | 0.1502 | 0.4486 |
Brugia malayi | MH2 domain containing protein | 0.013 | 0.1748 | 0.3935 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.0593 | 0.3946 |
Trichomonas vaginalis | ferritin, putative | 0.0009 | 0.0046 | 0.0069 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0067 | 0.0862 | 0.2396 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0007 | 0.003 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0434 |
Echinococcus granulosus | inositol monophosphatase | 0.0008 | 0.0037 | 0.0084 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.0593 | 0.1334 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0046 | 0.0127 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0152 | 0.2066 | 0.4651 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0069 | 0.0155 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0361 | 0.1002 |
Mycobacterium leprae | Probable monophosphatase | 0.0008 | 0.0037 | 0.0079 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0361 | 0.0812 |
Brugia malayi | beta-lactamase family protein | 0.0112 | 0.1502 | 0.338 |
Brugia malayi | beta-lactamase | 0.0112 | 0.1502 | 0.338 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0283 | 0.0638 |
Loa Loa (eye worm) | beta-lactamase | 0.0112 | 0.1502 | 0.338 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0007 | 0.003 | 0.0015 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0016 | 0.0156 | 0.0404 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0007 | 0.003 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.0007 | 0.0024 | 0.0068 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0206 | 0.0573 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0007 | 0.0024 | 0.0009 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.0593 | 0.3847 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0007 | 0.003 | 0.0036 |
Onchocerca volvulus | 0.001 | 0.0069 | 0.0119 | |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.4442 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0321 | 0.4442 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0623 | 0.1403 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.0283 | 0.1753 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0156 | 0.0891 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0007 | 0.0024 | 0.0055 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0283 | 0.1753 |
Onchocerca volvulus | 0.0112 | 0.1502 | 0.4474 | |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0193 | 0.1281 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0623 | 0.1403 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0623 | 0.1403 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0007 | 0.003 | 0.0036 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0069 | 0.0191 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.0283 | 0.1753 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0049 | 0.0135 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0016 | 0.0156 | 0.0891 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0048 | 0.0602 | 0.1355 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0076 | 0.0999 | 0.6601 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0112 | 0.1502 | 0.1489 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0069 | 0.0119 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0069 | 0.0155 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0283 | 0.0638 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0069 | 0.0191 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.003 | 0.0036 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0069 | 0.0155 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0069 | 0.0155 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0007 | 0.003 | 0.0034 |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.0294 | 0.0662 |
Schistosoma mansoni | apoferritin-2 | 0.0009 | 0.0046 | 0.0127 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0009 | 0.0048 | 0.0134 |
Schistosoma mansoni | inositol monophosphatase | 0.0076 | 0.0999 | 0.2777 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.003 | 0.0067 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0206 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0361 | 0.0812 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0156 | 0.0891 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0069 | 0.0155 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | inositol-1 | 0.0076 | 0.0999 | 0.225 |
Schistosoma mansoni | ferritin light chain | 0.0009 | 0.0046 | 0.0127 |
Trichomonas vaginalis | diphosphonucleoside phosphohydrolase, putative | 0.0008 | 0.0037 | 0.0043 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0016 | 0.0156 | 0.0891 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0016 | 0.0156 | 0.0404 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0602 | 0.1355 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0069 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2066 | 0.4651 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0005 | 0.0001 | 0.0002 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0069 | 0.0191 |
Onchocerca volvulus | 0.0026 | 0.0283 | 0.0771 | |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0063 | 0.0815 | 0.535 |
Schistosoma mansoni | smad | 0.0009 | 0.0049 | 0.0135 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0112 | 0.1502 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.003 | 0.0021 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0069 | 0.0119 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0007 | 0.0024 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0193 | 0.0434 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0104 | 0.1389 | 0.3126 |
Schistosoma mansoni | myo inositol monophosphatase | 0.0008 | 0.0037 | 0.0103 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0049 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.1502 | 0.338 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0069 | 0.0155 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.0049 | 0.011 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0007 | 0.0024 | 0.0055 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0069 | 0.0191 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0206 | 0.1817 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.013 | 0.1748 | 0.3935 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0016 | 0.0156 | 0.2668 |
Brugia malayi | Cytochrome P450 family protein | 0.0007 | 0.0024 | 0.0055 |
Mycobacterium ulcerans | lipase LipD | 0.0112 | 0.1502 | 1 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0007 | 0.003 | 0.0015 |
Leishmania major | myo-inositol-1 phosphatase, putative | 0.0008 | 0.0037 | 0.0085 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.003 | 0.0036 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0046 | 0.0127 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0206 | 0.1229 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0007 | 0.003 | 0.0036 |
Toxoplasma gondii | propionate-CoA ligase | 0.0007 | 0.003 | 0.0036 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0283 | 0.0638 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0361 | 0.1002 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0156 | 0.0891 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0069 | 0.0155 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0283 | 0.2615 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0178 | 0.0163 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0076 | 0.0999 | 0.2962 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0069 | 0.0155 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0206 | 0.1682 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0001 | 0.0002 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0069 | 0.0155 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0193 | 0.0178 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0007 | 0.003 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.1502 | 0.338 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.012 | 0.1619 | 0.1606 |
Brugia malayi | Inositol monophosphatase family protein | 0.0008 | 0.0037 | 0.0084 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0005 | 0.0001 | 0.0002 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0112 | 0.1502 | 0.4172 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0009 | 0.0046 | 0.0133 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0193 | 1 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.003 | 0.0036 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0048 | 0.0108 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0007 | 0.003 | 0.0036 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.003 | 0.0015 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0049 | 0.011 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0007 | 0.0024 | 0.0009 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.003 | 0.0067 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0007 | 0.003 | 0.0036 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.069 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.