Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4413 | 0.5495 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0486 | 0.0546 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.3293 | 0.4427 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.1195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.1195 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0166 | 0.139 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.1195 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.4413 | 0.5956 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.1195 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.4413 | 0.3655 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1195 | 0.124 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.1195 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.1195 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.3712 | 0.3972 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0667 | 0.0774 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.1195 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0067 | 0.7988 | 1 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0486 | 0.0592 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.1195 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.4413 | 0.4733 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.1195 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1195 | 0.124 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.1195 | 0.5 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0166 | 0.5 |
Onchocerca volvulus | 0.0025 | 0.1195 | 0.5 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.4413 | 0.5956 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.1195 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.1195 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4413 | 0.5495 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0063 | 0.7374 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.3293 | 0.4427 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0166 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.9266 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.4413 | 0.5956 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.1195 | 0.5 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0158 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1195 | 0.124 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0063 | 0.7374 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.1195 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0995 | 0.1188 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4413 | 0.5495 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.1195 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.1195 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.4446 | 0.4769 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.1195 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.4118 | 0.4413 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0166 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0667 | 0.0667 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0995 | 0.1287 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0486 | 0.0592 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.1195 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.4413 | 0.5956 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.37 | 0.2845 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0995 | 0.1287 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.1401 | 0.0234 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.