Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | Curated by TDR Targets | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | oxidoreductase | 0.0015 | 0.0218 | 0.0294 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0015 | 0.0218 | 0.0294 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0038 | 0.0715 | 0.1216 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0132 | 0.0225 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0015 | 0.0207 | 0.0281 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Schistosoma mansoni | DNA polymerase eta | 0.0151 | 0.3227 | 0.3227 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.003 | 0.0552 | 0.0691 |
Leishmania major | DNA damage repair protein, putative | 0.003 | 0.0552 | 0.0691 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0015 | 0.0207 | 0.0219 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0015 | 0.0218 | 0.036 |
Onchocerca volvulus | 0.0015 | 0.0207 | 0.106 | |
Brugia malayi | DnaJ domain containing protein | 0.006 | 0.1222 | 0.2085 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0015 | 0.0218 | 0.0157 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.003 | 0.0552 | 0.0691 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0159 | 0.3418 | 0.4614 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0132 | 0.0132 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.028 | 0.028 |
Echinococcus multilocularis | dna polymerase kappa | 0.0127 | 0.2697 | 0.2697 |
Echinococcus granulosus | discoidin domain containing receptor 2 | 0.0012 | 0.0144 | 0.0144 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0093 | 0.1949 | 0.1949 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0015 | 0.0218 | 0.036 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0015 | 0.0207 | 0.0207 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0041 | 0.0797 | 0.1485 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0015 | 0.0207 | 0.0337 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0223 | 0.4838 | 1 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0015 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0708 | 0.1207 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0218 | 0.0371 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0127 | 0.2697 | 0.3628 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0097 | 0.2039 | 0.4161 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0041 | 0.0797 | 0.0797 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0015 | 0.0218 | 0.0294 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0015 | 0.0218 | 0.0294 |
Brugia malayi | polk-prov protein | 0.006 | 0.1209 | 0.2063 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0132 | 0.0225 |
Trypanosoma brucei | unspecified product | 0.012 | 0.2534 | 0.3404 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0015 | 0.0218 | 0.0061 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0014 | 0.0024 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.028 | 0.0478 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0132 | 0.0225 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0015 | 0.0218 | 0.0234 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0015 | 0.0207 | 0.0337 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0014 | 0.0024 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.003 | 0.0552 | 0.0691 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0223 | 0.4838 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0337 | 0.7353 | 1 |
Mycobacterium ulcerans | glutaminase | 0.027 | 0.5864 | 1 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.003 | 0.0552 | 0.0869 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0041 | 0.0797 | 0.0797 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Schistosoma mansoni | kinase | 0.0047 | 0.0933 | 0.0933 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.005 | 0.0987 | 0.426 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0008 | 0.0062 | 0.0062 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.0015 | 0.0218 | 0.0294 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0105 | 0.2203 | 0.2951 |
Toxoplasma gondii | hypothetical protein | 0.0054 | 0.1087 | 0.2009 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0905 | 0.1481 |
Mycobacterium ulcerans | hypothetical protein | 0.003 | 0.0552 | 0.0868 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0015 | 0.0218 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0207 | 0.0352 |
Echinococcus multilocularis | discoidin domain containing receptor 2 | 0.0012 | 0.0144 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0014 | 0.0024 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0015 | 0.0207 | 0.0352 |
Leishmania major | DNA polymerase kappa, putative | 0.0105 | 0.2203 | 0.2951 |
Loa Loa (eye worm) | TK/ALK protein kinase | 0.0018 | 0.028 | 0.0478 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.0987 | 0.1966 |
Onchocerca volvulus | 0.005 | 0.0987 | 0.5066 | |
Echinococcus multilocularis | discoidin domain receptor | 0.0012 | 0.0144 | 0.0144 |
Onchocerca volvulus | 0.0015 | 0.0207 | 0.106 | |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0015 | 0.0207 | 0.0275 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0014 | 0.0024 |
Trypanosoma brucei | unspecified product | 0.0067 | 0.137 | 0.1811 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0015 | 0.0207 | 0.0337 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0093 | 0.1949 | 0.1949 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0015 | 0.0218 | 0.0234 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1949 | 0.3274 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0015 | 0.0218 | 0.036 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0015 | 0.0207 | 0.0219 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.0015 | 0.0218 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0132 | 0.0225 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0015 | 0.0207 | 0.0133 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.006 | 0.1209 | 0.1591 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0132 | 0.0225 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0015 | 0.0207 | 0.0133 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.005 | 0.0987 | 0.426 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Onchocerca volvulus | 0.0017 | 0.0252 | 0.1294 | |
Echinococcus granulosus | dna polymerase kappa | 0.0127 | 0.2697 | 0.2697 |
Onchocerca volvulus | 0.0015 | 0.0218 | 0.1117 | |
Mycobacterium tuberculosis | Probable oxidase | 0.0007 | 0.0047 | 0.0003 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0015 | 0.0207 | 0.0337 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0015 | 0.0218 | 0.0234 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0015 | 0.0207 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0987 | 0.1684 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0041 | 0.0797 | 0.0797 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0127 | 0.2697 | 0.456 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0663 | 0.1289 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0252 | 0.0252 |
Brugia malayi | AMP-binding enzyme family protein | 0.0015 | 0.0207 | 0.0352 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0043 | 0.000000000076804 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0132 | 0.0225 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0015 | 0.0207 | 0.0352 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0207 | 0.0275 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0592 | 0.101 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0047 | 0.0933 | 0.1213 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.003 | 0.0552 | 0.0552 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0059 | 0.0059 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0097 | 0.2039 | 0.2039 |
Brugia malayi | Protein kinase domain containing protein | 0.0012 | 0.0144 | 0.0246 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0015 | 0.0207 | 0.0337 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0093 | 0.1949 | 1 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0015 | 0.0218 | 0.0234 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0015 | 0.0218 | 0.0234 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0223 | 0.4838 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0015 | 0.0207 | 0.0352 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0132 | 0.0225 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0015 | 0.0218 | 0.036 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0015 | 0.0218 | 0.036 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0132 | 0.0132 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0132 | 0.0132 |
Trypanosoma brucei | hypothetical protein, conserved | 0.003 | 0.0552 | 0.0691 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0084 | 0.1739 | 0.2317 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0132 | 0.0225 |
Schistosoma mansoni | hypothetical protein | 0.0456 | 1 | 1 |
Onchocerca volvulus | 0.0017 | 0.0252 | 0.1294 | |
Giardia lamblia | DINP protein human, muc B family | 0.0105 | 0.2203 | 1 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0223 | 0.4838 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.003 | 0.0552 | 0.0691 |
Onchocerca volvulus | 0.0011 | 0.0132 | 0.0678 | |
Mycobacterium ulcerans | hypothetical protein | 0.005 | 0.0987 | 0.1617 |
Loa Loa (eye worm) | DnaJ domain-containing protein | 0.006 | 0.1222 | 0.2085 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0132 | 0.0132 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0132 | 0.0225 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0177 | 0.3817 | 0.7871 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0015 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0987 | 0.1684 |
Brugia malayi | AMP-binding enzyme family protein | 0.0015 | 0.0207 | 0.0352 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0015 | 0.0218 | 0.0371 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0097 | 0.2039 | 0.2039 |
Toxoplasma gondii | propionate-CoA ligase | 0.0015 | 0.0207 | 0.0133 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0132 | 0.0225 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0159 | 0.3418 | 0.4614 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0144 | 0.0246 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0043 | 0.000000000076804 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0015 | 0.0207 | 0.0337 |
Onchocerca volvulus | 0.0015 | 0.0207 | 0.106 | |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0015 | 0.0218 | 0.036 |
Schistosoma mansoni | septate junction protein | 0.0012 | 0.0144 | 0.0144 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0015 | 0.0218 | 0.0218 |
Brugia malayi | hypothetical protein | 0.0018 | 0.028 | 0.0478 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0207 | 0.0275 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0015 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0797 | 0.1359 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0252 | 0.043 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0015 | 0.0207 | 0.0133 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0015 | 0.0207 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0132 | 0.0225 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0132 | 0.0132 |
Trypanosoma brucei | hypothetical protein, conserved | 0.003 | 0.0552 | 0.0691 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0006 | 0.0014 | 0.0014 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0041 | 0.0797 | 0.0797 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0041 | 0.0797 | 0.0797 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0015 | 0.0207 | 0.0133 |
Echinococcus granulosus | Coagulation factor 5 8 type C terminal | 0.0075 | 0.1537 | 0.1537 |
Schistosoma mansoni | glutaminase | 0.027 | 0.5864 | 0.5864 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0015 | 0.0207 | 0.0337 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0047 | 0.0933 | 0.1213 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0015 | 0.0207 | 0.0352 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0592 | 0.0592 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0015 | 0.0207 | 0.0275 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0633 | 0.0633 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0015 | 0.0207 | 0.0219 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0132 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0132 | 0.0225 |
Brugia malayi | SEA domain containing protein | 0.0017 | 0.0252 | 0.043 |
Trichomonas vaginalis | hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0207 | 0.0275 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0097 | 0.2039 | 0.3478 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Loa Loa (eye worm) | DOMON domain-containing protein | 0.0017 | 0.0252 | 0.043 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0015 | 0.0218 | 0.036 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0015 | 0.0207 | 0.0219 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0074 | 0.1533 | 0.2034 |
Giardia lamblia | Kinase, PLK | 0.0093 | 0.1949 | 0.8464 |
Loa Loa (eye worm) | glutaminase | 0.027 | 0.5864 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0127 | 0.2697 | 0.4557 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0015 | 0.0218 | 0.0294 |
Schistosoma mansoni | discoidin domain receptor | 0.0012 | 0.0144 | 0.0144 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0015 | 0.0207 | 0.0275 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1949 | 0.3274 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0006 | 0.0014 | 0.0024 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0015 | 0.0218 | 0.0294 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.005 | 0.0987 | 0.1617 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0132 | 0.0225 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0006 | 0.0014 | 0.0014 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.012 | 0.2534 | 0.3404 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0708 | 0.1207 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0.0132 | 0.0678 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0127 | 0.2697 | 0.4557 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0014 | 0.0024 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0132 | 0.0225 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0015 | 0.0207 | 0.0133 |
Onchocerca volvulus | 0.0018 | 0.028 | 0.1438 | |
Trypanosoma brucei | unspecified product | 0.0067 | 0.137 | 0.1811 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.005 | 0.0987 | 0.1617 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.028 | 0.0478 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.1228 | 0.2309 |
Echinococcus multilocularis | nuclear receptor 2C2 associated protein | 0.0012 | 0.0144 | 0.0144 |
Brugia malayi | AMP-binding enzyme family protein | 0.005 | 0.0987 | 0.1684 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1949 | 0.3274 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0015 | 0.0207 | 0.0219 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | oxidoreductase | 0.0015 | 0.0218 | 0.0371 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0015 | 0.0207 | 0.0275 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0.0132 | 0.0678 |
Trichomonas vaginalis | protein kinase inhibitor, putative | 0.006 | 0.1222 | 0.2026 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0132 | 0.0225 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0132 | 0.0132 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0132 | 0.0132 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.0015 | 0.0218 | 0.0157 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0074 | 0.1533 | 0.2034 |
Leishmania major | DNA polymerase eta, putative | 0.0084 | 0.1739 | 0.2317 |
Echinococcus multilocularis | dnaJ subfamily C 6 | 0.006 | 0.1222 | 0.1222 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0041 | 0.0797 | 0.0797 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0132 | 0.0132 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0041 | 0.0797 | 0.0797 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Echinococcus multilocularis | dna polymerase eta | 0.0151 | 0.3227 | 0.3227 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0132 | 0.0225 |
Brugia malayi | glutaminase DH11.1 | 0.027 | 0.5864 | 1 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0041 | 0.0797 | 0.1027 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.003 | 0.0552 | 0.0691 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0093 | 0.1949 | 0.3324 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0132 | 0.0225 |
Onchocerca volvulus | 0.0017 | 0.0252 | 0.1294 | |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0041 | 0.0797 | 0.1027 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0043 | 0.000000000076804 |
Mycobacterium ulcerans | hypothetical protein | 0.0177 | 0.3817 | 0.6482 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0132 | 0.0225 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.003 | 0.0552 | 0.0691 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0337 | 0.7353 | 1 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0093 | 0.1949 | 0.9507 |
Onchocerca volvulus | 0.0017 | 0.0252 | 0.1294 | |
Plasmodium vivax | DNA repair protein REV1, putative | 0.003 | 0.0552 | 0.0869 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.005 | 0.0987 | 0.1288 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0592 | 0.101 |
Leishmania major | oxidoreductase-like protein | 0.0015 | 0.0218 | 0.0234 |
Echinococcus granulosus | discoidin domain receptor | 0.0012 | 0.0144 | 0.0144 |
Trichomonas vaginalis | hypothetical protein | 0.0223 | 0.4838 | 0.8237 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0015 | 0.0207 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0708 | 0.1207 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0663 | 0.1289 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0015 | 0.0218 | 0.0294 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0041 | 0.0797 | 0.1295 |
Onchocerca volvulus | 0.0032 | 0.0592 | 0.304 | |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0059 | 0.0059 |
Mycobacterium leprae | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI | 0.0015 | 0.0218 | 0.0157 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.005 | 0.0987 | 0.1617 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0037 | 0.0708 | 0.1137 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0337 | 0.7353 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0102 | 0.0102 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0037 | 0.0708 | 0.1061 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0097 | 0.2039 | 1 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0013 | 0.0161 | 0.0242 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0708 | 0.1207 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0059 | 0.0059 |
Schistosoma mansoni | dock | 0.0075 | 0.1537 | 0.1537 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0132 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0132 | 0.0225 |
Schistosoma mansoni | btb and poz domain-containing protein | 0.0012 | 0.0144 | 0.0144 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0015 | 0.0218 | 0.0218 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0015 | 0.0207 | 0.0337 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0015 | 0.0218 | 0.0371 |
Trypanosoma brucei | polo-like protein kinase | 0.0093 | 0.1949 | 0.2604 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0252 | 0.043 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.006 | 0.1209 | 0.1591 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0015 | 0.0207 | 0.0352 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0132 | 0.0132 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0151 | 0.3227 | 0.5503 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.005 | 0.0987 | 0.1617 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.005 | 0.0987 | 0.426 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0987 | 0.1684 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0015 | 0.0218 | 0.036 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0015 | 0.0218 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.3227 | 0.5503 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0105 | 0.2203 | 0.4502 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1949 | 0.3274 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1949 | 0.3274 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.005 | 0.0987 | 0.1797 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0015 | 0.0207 | 0.0275 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0037 | 0.0708 | 0.1201 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0014 | 0.0024 |
Brugia malayi | AMP-binding enzyme family protein | 0.0015 | 0.0207 | 0.0352 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0132 | 0.0225 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0132 | 0.0225 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0015 | 0.0218 | 0.0294 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0132 | 0.0132 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.1222 | 0.1222 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0093 | 0.1949 | 0.3324 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0015 | 0.0207 | 0.0275 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0097 | 0.2039 | 0.2039 |
Onchocerca volvulus | 0.0012 | 0.0144 | 0.0739 | |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0006 | 0.0014 | 0.0014 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.005 | 0.0987 | 0.1288 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0132 | 0.0225 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0099 | 0.0169 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0151 | 0.3227 | 0.4353 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0633 | 0.0633 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0663 | 0.1289 |
Onchocerca volvulus | 0.0017 | 0.0252 | 0.1294 | |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0015 | 0.0218 | 0.0294 |
Brugia malayi | nuclear receptor RXR | 0.0006 | 0.0014 | 0.0024 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0015 | 0.0207 | 0.0219 |
Echinococcus granulosus | dna polymerase eta | 0.0151 | 0.3227 | 0.3227 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0132 | 0.0225 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0037 | 0.0708 | 0.1383 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0058 | 0.1162 | 0.1527 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0207 | 0.0275 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0207 | 0.0275 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.005 | 0.0987 | 0.1617 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0059 | 0.0059 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.005 | 0.0987 | 0.1966 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1209 | 0.2063 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0015 | 0.0207 | 0.0219 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.0633 | 0.0633 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0015 | 0.0207 | 0.0275 |
Schistosoma mansoni | dihydropteridine reductase | 0.0015 | 0.0218 | 0.0218 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0223 | 0.4838 | 1 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0012 | 0.0144 | 0.0173 |
Schistosoma mansoni | discoidin domain receptor | 0.0012 | 0.0144 | 0.0144 |
Onchocerca volvulus | 0.0015 | 0.0207 | 0.106 | |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0015 | 0.0207 | 0.0133 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0456 | 1 | 1 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.003 | 0.0552 | 0.0691 |
Brugia malayi | AMP-binding enzyme family protein | 0.005 | 0.0987 | 0.1684 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0223 | 0.4838 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.003 | 0.0552 | 0.0869 |
Echinococcus granulosus | discoidin domain containing receptor 2 | 0.0012 | 0.0144 | 0.0144 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0132 | 0.0225 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0132 | 0.0225 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0207 | 0.0275 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0151 | 0.3227 | 0.4353 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.005 | 0.0987 | 0.1617 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0132 | 0.0132 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0132 | 0.0225 |
Brugia malayi | AMP-binding enzyme family protein | 0.005 | 0.0987 | 0.1684 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0043 | 0.000000000076804 |
Echinococcus granulosus | dnaJ subfamily C 6 | 0.006 | 0.1222 | 0.1222 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0015 | 0.0218 | 0.0371 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0015 | 0.0207 | 0.0281 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0015 | 0.0207 | 0.0275 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.028 | 0.028 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.005 | 0.0987 | 0.1288 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0663 | 0.1289 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0223 | 0.4838 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0068 | 0.1389 | 0.1389 |
Onchocerca volvulus | 0.0015 | 0.0218 | 0.1117 | |
Echinococcus multilocularis | discoidin domain containing receptor 2 | 0.0012 | 0.0144 | 0.0144 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0905 | 0.1481 |
Onchocerca volvulus | 0.0012 | 0.0144 | 0.0739 | |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0102 | 0.0102 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0084 | 0.1739 | 0.3399 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0132 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0018 | 0.0032 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0.0132 | 0.0678 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Echinococcus multilocularis | MAM | 0.0018 | 0.028 | 0.028 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0041 | 0.0797 | 0.1027 |
Echinococcus granulosus | discoidin domain containing receptor 2 | 0.0012 | 0.0144 | 0.0144 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0223 | 0.4838 | 0.8236 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0132 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0132 | 0.0225 |
Trichomonas vaginalis | glutaminase, putative | 0.027 | 0.5864 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0014 | 0.0024 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0041 | 0.0797 | 0.1359 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0015 | 0.0218 | 0.0294 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0041 | 0.0797 | 0.1027 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.028 | 0.0478 |
Brugia malayi | AMP-binding enzyme family protein | 0.0015 | 0.0207 | 0.0352 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0041 | 0.0797 | 0.0797 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0043 | 0.000000000076804 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0015 | 0.0218 | 0.0234 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0015 | 0.0218 | 0.0294 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0093 | 0.1949 | 0.2604 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0093 | 0.1949 | 0.2604 |
Loa Loa (eye worm) | glutaminase 2 | 0.027 | 0.5864 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.0633 | 0.0633 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.028 | 0.0478 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0132 | 0.0132 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0105 | 0.2203 | 0.2951 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0159 | 0.3418 | 0.4614 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0015 | 0.0218 | 0.0294 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0015 | 0.0207 | 0.0337 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0041 | 0.0797 | 0.1295 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0015 | 0.0218 | 0.036 |
Onchocerca volvulus | 0.0018 | 0.028 | 0.1438 | |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0015 | 0.0207 | 0.0337 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0127 | 0.2697 | 0.456 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.005 | 0.0987 | 0.1617 |
Leishmania major | pteridine reductase 1 | 0.0015 | 0.0218 | 0.0234 |
Echinococcus granulosus | MAM | 0.0018 | 0.028 | 0.028 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0127 | 0.2697 | 0.3628 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0132 | 0.0132 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0015 | 0.0207 | 0.0207 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0144 | 0.0173 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0015 | 0.0218 | 0.0294 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.005 | 0.0987 | 0.1797 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0012 | 0.0144 | 0.0173 |
Leishmania major | DNA polymerase eta, putative | 0.0151 | 0.3227 | 0.4353 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0015 | 0.0218 | 0.0157 |
Trypanosoma brucei | pteridine reductase 1 | 0.0015 | 0.0218 | 0.0234 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0207 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0014 | 0.0024 |
Echinococcus multilocularis | discoidin domain containing receptor 2 | 0.0012 | 0.0144 | 0.0144 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0097 | 0.2039 | 0.3478 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0074 | 0.1533 | 0.2034 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0015 | 0.0218 | 0.0294 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0014 | 0.0024 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0093 | 0.1949 | 0.2604 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0015 | 0.0207 | 0.0337 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1949 | 0.3274 |
Trichomonas vaginalis | beta-hexosaminidase B, putative | 0.0012 | 0.0144 | 0.0173 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0015 | 0.0218 | 0.0234 |
Brugia malayi | Protein kinase domain containing protein | 0.0018 | 0.028 | 0.0478 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0337 | 0.7353 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0132 | 0.0132 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0132 | 0.0225 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Brugia malayi | CUB domain containing protein | 0.0006 | 0.0018 | 0.0032 |
Brugia malayi | Muscle positioning protein 4 | 0.0017 | 0.0252 | 0.043 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0132 | 0.0225 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0043 | 0.000000000076804 |
Echinococcus multilocularis | Coagulation factor 5 8 type, C terminal | 0.0075 | 0.1537 | 0.1537 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0015 | 0.0218 | 0.0234 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0144 | 0.0144 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0218 | 0.0294 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0047 | 0.0933 | 0.1213 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0127 | 0.2697 | 0.3628 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0102 | 0.0174 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0132 | 0.0132 |
Leishmania major | DNA polymerase kappa, putative | 0.003 | 0.0552 | 0.0691 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0015 | 0.0207 | 0.0275 |
Mycobacterium leprae | POSSIBLE OXIDOREDUCTASE | 0.0015 | 0.0218 | 0.0157 |
Echinococcus multilocularis | dedicator of cytokinesis protein | 0.0063 | 0.1275 | 0.1275 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.1949 | 0.3274 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0043 | 0.000000000076804 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0132 | 0.0225 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0041 | 0.0797 | 0.322 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0093 | 0.1949 | 0.1949 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0043 | 0.000000000076804 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0047 | 0.0933 | 0.1213 |
Mycobacterium tuberculosis | Possible arabinofuranosyltransferase AftD | 0.0012 | 0.0144 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0708 | 0.1207 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0132 | 0.0132 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0006 | 0.0014 | 0.0014 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0132 | 0.0225 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0037 | 0.0708 | 0.1201 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0015 | 0.0218 | 0.0157 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0097 | 0.2039 | 0.2039 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0207 | 0.0275 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0797 | 0.1295 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0207 | 0.0352 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0132 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0144 | 0.0246 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
Affected Entity | Phenotypic quality | Occurs in | Occurs at | Evidence | Observed in | Targets |
---|---|---|---|---|---|---|
catalytic activity (GO:0003824) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Mycobacterium tuberculosis | 6263 | |
Annotator: | crowther@u.washington.edu | Comment: | 2007-12-07 | References: | 15239654 |
1 literature reference was collected for this gene.