Detailed information for compound 575226

Basic information

Technical information
  • TDR Targets ID: 575226
  • Name: arsorosobenzene
  • MW: 168.025 | Formula: C6H5AsO
  • H donors: 0 H acceptors: 1 LogP: 1.22 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=[As]c1ccccc1
  • InChi: 1S/C6H5AsO/c8-7-6-4-2-1-3-5-6/h1-5H
  • InChiKey: BQVCCPGCDUSGOE-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • oxophenylarsine
  • 8052-79-7
  • 637-03-6
  • AIDS-082246
  • 4-16-00-01160 (Beilstein Handbook Reference)
  • BRN 2935227
  • Caswell No. 060
  • EINECS 211-275-3
  • Arsenosobenzene
  • Arsine, oxophenyl-
  • Arzene
  • Benzene, arsenoso-
  • NSC42470
  • Phenyl arsenoxide
  • Phenyl arsine oxide
  • Phenylarsenoxide
  • Phenylarsine oxide
  • WLN: O-AS-R
  • Fenylarsinoxid [Czech]
  • EPA Pesticide Chemical Code 007101
  • AIDS082246
  • P3075_SIGMA
  • NSC 42470

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Starlite/ChEMBL No references
Homo sapiens peroxisome proliferator-activated receptor delta Starlite/ChEMBL No references
Leishmania major beta tubulin Curated by TDR Targets References
Homo sapiens heat shock 27kDa protein 1 Starlite/ChEMBL No references
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major gamma-tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major delta tubulin, putative Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major epsilon tubulin, putative Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Homo sapiens androgen receptor Starlite/ChEMBL No references
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Homo sapiens jun proto-oncogene Starlite/ChEMBL No references
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major zeta tubulin, putative Curated by TDR Targets References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium vivax tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Brugia malayi Tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin beta-7 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Basic leucine zipper bZIP transcription factor Get druggable targets OG5_131442 All targets in OG5_131442
Echinococcus multilocularis tubulin epsilon chain Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin subunit TubB Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein Get druggable targets OG5_130726 All targets in OG5_130726
Plasmodium berghei tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium falciparum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii alpha tubulin TUBA1 Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi tubulin alpha chain - mouse Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Trypanosoma brucei gambiense alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Candida albicans cytoskeletal structural protein Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum alpha tubulin 2 Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Trypanosoma cruzi tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma japonicum Tubulin alpha-1C chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi alpha tubulin, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor Get druggable targets OG5_131442 All targets in OG5_131442
Babesia bovis tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania mexicana alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Plasmodium knowlesi tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium berghei tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Giardia lamblia Alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Trypanosoma cruzi epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin, beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Brugia malayi bZIP transcription factor family protein Get druggable targets OG5_131442 All targets in OG5_131442
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Babesia bovis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii Tubulin/FtsZ family, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium falciparum alpha tubulin 1 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Plasmodium knowlesi alpha tubulin, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium berghei tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum ko:K07374 tubulin alpha, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium berghei alpha tubulin 1 Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis peroxisome assembly protein 26 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus granulosus tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Cryptosporidium parvum gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma japonicum Tubulin beta-4 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii beta-1 tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium knowlesi tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Plasmodium yoelii tubulin beta chain Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum tubulin delta chain, putative Get druggable targets OG5_143817 All targets in OG5_143817
Schistosoma japonicum Tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K07374 tubulin alpha, putative Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Candida albicans gamma tubulin-like protein Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Toxoplasma gondii alpha-tubulin I, putative Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium parvum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma japonicum Tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma congolense zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Cryptosporidium hominis alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania donovani epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Cryptosporidium hominis gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin subunit TubB Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum Beta-tubulin, related Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K10391 tubulin epsilon, putative Get druggable targets OG5_130726 All targets in OG5_130726
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Entamoeba histolytica tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin alpha-2/alpha-4 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131442 All targets in OG5_131442
Trypanosoma cruzi tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium berghei alpha tubulin 2 Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis jun protein Get druggable targets OG5_131442 All targets in OG5_131442
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin, putative Get druggable targets OG5_127652 All targets in OG5_127652
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus granulosus peroxisome assembly protein 26 Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin gamma 1 chain Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania donovani alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi beta tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi Tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Plasmodium yoelii tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania donovani tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Plasmodium falciparum tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein Get druggable targets OG5_143817 All targets in OG5_143817
Neospora caninum tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi beta-tubulin, identical Get druggable targets OG5_126611 All targets in OG5_126611
Theileria parva Tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus multilocularis tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Theileria parva tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium vivax tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Theileria parva tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin alpha chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi small heat shock protein Get druggable targets OG5_141248 All targets in OG5_141248
Cryptosporidium parvum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) alpha-tubulin isotype 2 Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania donovani zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin alpha-3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit epsilon Get druggable targets OG5_130726 All targets in OG5_130726
Loa Loa (eye worm) beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus granulosus tubulin epsilon chain Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum ko:K10389 tubulin gamma, putative Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) tubulin beta-2A chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Trypanosoma brucei zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Babesia bovis tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Candida albicans gamma tubulin-like protein Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma congolense tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_141248 All targets in OG5_141248
Babesia bovis tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin gamma 1 chain Get druggable targets OG5_127652 All targets in OG5_127652
Entamoeba histolytica tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Entamoeba histolytica tubulin alpha-1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania donovani tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Trichomonas vaginalis tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Cryptosporidium hominis beta-catenin-like repeat protein Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma cruzi zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Toxoplasma gondii beta-tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit gamma Get druggable targets OG5_127652 All targets in OG5_127652
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) tubulin beta-4 chain Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus jun protein Get druggable targets OG5_131442 All targets in OG5_131442
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium knowlesi alpha-tubulin II, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Theileria parva tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Brugia malayi tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Brugia malayi ecdysteroid receptor peroxisome proliferator-activated receptor delta 441 aa 369 aa 24.7 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Brugia malayi Hsp20/alpha crystallin family protein heat shock 27kDa protein 1 205 aa 168 aa 25.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin epsilon chain, putative gamma-tubulin 447 aa 479 aa 28.2 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Trypanosoma brucei epsilon tubulin epsilon tubulin, putative 470 aa 488 aa 68.0 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis Tubulin alpha 1 chain 0.0471 0.1057 0.1046
Mycobacterium tuberculosis Cell division protein FtsZ 0.0161 0.0315 0.9753
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0401 0.0889 0.6195
Trypanosoma cruzi phosphoglycerate kinase, putative 0.006 0.0074 0.0412
Echinococcus multilocularis tubulin alpha chain 0.0471 0.1057 0.1046
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0074 0.0107 0.054
Brugia malayi AMP-binding enzyme family protein 0.0123 0.0224 0.1399
Giardia lamblia Phosphoglycerate kinase 0.0164 0.0323 0.2139
Echinococcus granulosus alpha tubulin 0.0471 0.1057 0.6007
Loa Loa (eye worm) hypothetical protein 0.0092 0.0149 0.0934
Brugia malayi ecdysteroid receptor 0.0074 0.0107 0.0669
Brugia malayi nuclear receptor RXR 0.0035 0.0013 0.0083
Schistosoma mansoni retinoic acid receptor RXR 0.0074 0.0107 0.0268
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.0221 0.1382
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.005 0.0304
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0045 0.0181
Loa Loa (eye worm) hypothetical protein 0.0152 0.0294 0.1835
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0074 0.0107 0.1299
Loa Loa (eye worm) hypothetical protein 0.0092 0.0149 0.0934
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0074 0.0107 0.0669
Trypanosoma brucei alpha tubulin 0.0471 0.1057 0.7386
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Schistosoma mansoni RAR-like nuclear receptor 0.0074 0.0107 0.0268
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0164 0.0323 0.2181
Schistosoma mansoni tubulin subunit gamma 0.0384 0.0849 0.2392
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0074 0.0107 0.0669
Echinococcus multilocularis tubulin subunit beta 0.0625 0.1426 0.1415
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0137 0.418
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0036 0.0016 0.0376
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0039 0.0023 0.0146
Onchocerca volvulus Pyruvate kinase homolog 0.014 0.0264 0.3476
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0074 0.0107 0.054
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.028 0.0267
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0164 0.0323 1
Echinococcus granulosus geminin 0.0528 0.1194 0.6795
Trypanosoma brucei beta tubulin 0.0625 0.1426 1
Loa Loa (eye worm) hypothetical protein 0.0123 0.0224 0.1399
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0023 0.0053
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.1426 0.8127
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0023 0.0053
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0074 0.0107 0.0094
Loa Loa (eye worm) nuclear receptor NHR-67 0.0035 0.0013 0.0083
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0224 0.6765
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Plasmodium vivax pyruvate kinase 2, putative 0.0072 0.0101 0.0606
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0035 0.0013 0.0083
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0164 0.0323 0.2181
Trypanosoma brucei phosphoglycerate kinase, putative 0.006 0.0074 0.0412
Giardia lamblia Gamma tubulin 0.0384 0.0849 0.589
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0023 0.0053
Leishmania major beta tubulin 0.0625 0.1426 1
Onchocerca volvulus 0.0036 0.0016 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0074 0.0107 0.0669
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.006 0.0074 0.0412
Loa Loa (eye worm) hypothetical protein 0.0039 0.0023 0.0146
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0039 0.0023 0.0058
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0101 0.0172 0.0916
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0036 0.0016 0.0066
Entamoeba histolytica hypothetical protein 0.0146 0.028 0.1875
Echinococcus multilocularis tubulin alpha chain 0.0471 0.1057 0.1046
Loa Loa (eye worm) hypothetical protein 0.0104 0.0178 0.1115
Echinococcus granulosus tubulin subunit TubB 0.0471 0.1057 0.6007
Schistosoma mansoni phosphoglycerate kinase 0.0164 0.0323 0.0887
Echinococcus multilocularis tubulin subunit TubB 0.0471 0.1057 0.1046
Brugia malayi bZIP transcription factor family protein 0.0101 0.0172 0.1077
Loa Loa (eye worm) hypothetical protein 0.0074 0.0107 0.0669
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0625 0.1426 0.1415
Loa Loa (eye worm) tubulin gamma chain 0.0384 0.0849 0.5308
Schistosoma mansoni steroid hormone receptor ad4bp 0.0074 0.0107 0.0268
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.028 0.1536
Plasmodium vivax tubulin alpha chain, putative 0.0471 0.1057 0.7386
Brugia malayi Tubulin alpha chain 0.0471 0.1057 0.6607
Schistosoma mansoni tubulin subunit delta 0.0161 0.0315 0.0864
Loa Loa (eye worm) hypothetical protein 0.0074 0.0107 0.0669
Schistosoma mansoni phosphoglycerate kinase 0.0164 0.0323 0.0887
Trypanosoma brucei tubulin gamma chain 0.0384 0.0849 0.5912
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0036 0.0016 0.0003
Schistosoma mansoni acetyl-CoA synthetase 0.0036 0.0016 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0074 0.0107 0.0094
Loa Loa (eye worm) hypothetical protein 0.0039 0.0023 0.0146
Schistosoma mansoni hypothetical protein 0.0166 0.0327 0.0896
Schistosoma mansoni alpha tubulin 0.0471 0.1057 0.2987
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0074 0.0107 0.054
Trypanosoma cruzi zeta tubulin, putative 0.0498 0.1123 0.7849
Toxoplasma gondii pyruvate kinase PyK1 0.014 0.0264 0.1817
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0016 0.0099
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0074 0.0107 0.0094
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0142 0.0744
Onchocerca volvulus Protein ultraspiracle homolog 0.0074 0.0107 0.1299
Onchocerca volvulus 0.0123 0.0224 0.2915
Echinococcus granulosus FTZ F1 alpha 0.0074 0.0107 0.054
Echinococcus multilocularis Tubulin alpha 1 chain 0.0471 0.1057 0.1046
Brugia malayi Tubulin beta-1 chain 0.0625 0.1426 0.8909
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0074 0.0107 0.0669
Loa Loa (eye worm) hypothetical protein 0.0123 0.0224 0.1399
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0036 0.0016 0.0376
Toxoplasma gondii beta-1 tubulin, putative 0.0625 0.1426 1
Echinococcus granulosus beta tubulin 0.0625 0.1426 0.8127
Toxoplasma gondii beta-tubulin, putative 0.0625 0.1426 1
Leishmania major beta tubulin 0.0625 0.1426 1
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0023 0.0146
Giardia lamblia Pyruvate kinase 0.014 0.0264 0.1719
Echinococcus multilocularis pyruvate kinase 0.014 0.0264 0.0251
Schistosoma mansoni tubulin subunit beta 0.0625 0.1426 0.4041
Brugia malayi hypothetical protein 0.008 0.012 0.0751
Echinococcus granulosus Niemann Pick C1 protein 0.0573 0.1301 0.7411
Mycobacterium leprae cell division protein FtsZ 0.0161 0.0315 0.9744
Brugia malayi nuclear hormone receptor family member nhr-6 0.0035 0.0013 0.0083
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.1426 0.1415
Brugia malayi nuclear receptor NHR-88 0.0074 0.0107 0.0669
Loa Loa (eye worm) hypothetical protein 0.0092 0.0149 0.0934
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0074 0.0107 0.0669
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0016 0.0376
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0016 0.0099
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0045 0.0279
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Echinococcus granulosus tubulin alpha chain 0.0471 0.1057 0.6007
Plasmodium vivax acyl-CoA synthetase, putative 0.0092 0.0149 0.0947
Brugia malayi orphan nuclear receptor NR2E1 0.0035 0.0013 0.0083
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0036 0.0016 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0074 0.0107 0.054
Loa Loa (eye worm) alpha-tubulin 0.0471 0.1057 0.6607
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Loa Loa (eye worm) tubulin beta-4 chain 0.0625 0.1426 0.8909
Entamoeba histolytica hypothetical protein 0.0146 0.028 0.1875
Trypanosoma brucei phosphoglycerate kinase 0.0164 0.0323 0.2181
Trichomonas vaginalis tubulin, putative 0.0625 0.1426 1
Leishmania major beta tubulin 0.0625 0.1426 1
Leishmania major phosphoglycerate kinase B, cytosolic 0.0164 0.0323 0.2181
Leishmania major beta tubulin 0.0625 0.1426 1
Loa Loa (eye worm) tubulin beta-2A chain 0.0625 0.1426 0.8909
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0074 0.0107 0.0669
Loa Loa (eye worm) tubulin alpha-2 chain 0.0471 0.1057 0.6607
Echinococcus multilocularis pyruvate kinase 0.011 0.0194 0.0181
Leishmania major beta tubulin 0.0625 0.1426 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0074 0.0107 0.054
Echinococcus multilocularis tubulin alpha 1C chain 0.0471 0.1057 0.1046
Trichomonas vaginalis tubulin gamma chain, putative 0.0625 0.1426 1
Echinococcus multilocularis tubulin alpha 1C chain 0.0471 0.1057 0.1046
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0036 0.0016 0.0376
Echinococcus granulosus tubulin alpha chain 0.0471 0.1057 0.6007
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0045 0.0279
Schistosoma mansoni hypothetical protein 0.0146 0.028 0.0764
Trichomonas vaginalis tubulin gamma chain, putative 0.0161 0.0315 0.2125
Trypanosoma brucei zeta tubulin 0.0498 0.1123 0.7849
Schistosoma mansoni tubulin subunit beta 0.0625 0.1426 0.4041
Trypanosoma brucei phosphoglycerate kinase 0.0164 0.0323 0.2181
Schistosoma mansoni hypothetical protein 0.0528 0.1194 0.3378
Loa Loa (eye worm) hypothetical protein 0.0172 0.0341 0.2133
Brugia malayi photoreceptor-specific nuclear receptor 0.0074 0.0107 0.0669
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0351 0.0771 0.5389
Echinococcus granulosus GPCR family 2 0.0048 0.0045 0.0181
Loa Loa (eye worm) hypothetical protein 0.0039 0.0023 0.0146
Toxoplasma gondii exonuclease III APE 0.0039 0.0023 0.0119
Schistosoma mansoni hypothetical protein 0.0082 0.0127 0.0325
Echinococcus multilocularis tumor protein p63 0.0326 0.0711 0.0699
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0074 0.0107 0.0268
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0039 0.0023 0.001
Onchocerca volvulus Pyruvate kinase homolog 0.014 0.0264 0.3476
Giardia lamblia Beta tubulin 0.0625 0.1426 1
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0164 0.0323 0.2232
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0045 0.0279
Schistosoma mansoni microtubule-associated protein tau 0.0761 0.1751 0.4972
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0036 0.0016 0.0376
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.0221 0.1382
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0074 0.0107 0.0669
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.028 0.0764
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.1426 0.1415
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0074 0.0107 0.0669
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0023 0.0053
Schistosoma mansoni thyroid hormone receptor 0.0074 0.0107 0.0268
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0074 0.0107 0.0094
Plasmodium falciparum pyruvate kinase 2 0.0072 0.0101 0.0606
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0074 0.0107 0.0669
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0036 0.0016 0.0066
Plasmodium vivax pyruvate kinase, putative 0.014 0.0264 0.1762
Echinococcus multilocularis tubulin alpha 3 chain 0.0471 0.1057 0.1046
Trypanosoma brucei tubulin delta chain 0.0363 0.0798 0.5549
Entamoeba histolytica acyl-CoA synthetase, putative 0.0123 0.0224 0.1475
Schistosoma mansoni pyruvate kinase 0.014 0.0264 0.0718
Entamoeba histolytica hypothetical protein 0.0146 0.028 0.1875
Echinococcus multilocularis GPCR, family 2 0.0048 0.0045 0.0031
Plasmodium falciparum tubulin beta chain 0.0625 0.1426 1
Echinococcus multilocularis tubulin alpha 3 chain 0.0471 0.1057 0.1046
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0074 0.0107 0.0669
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0092 0.0149 0.4557
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0074 0.0107 0.0669
Leishmania major phosphoglycerate kinase C, glycosomal 0.0164 0.0323 0.2181
Brugia malayi hypothetical protein 0.0032 0.0007 0.0044
Loa Loa (eye worm) nuclear hormone receptor 0.0035 0.0013 0.0083
Echinococcus multilocularis thyroid hormone receptor alpha 0.0074 0.0107 0.0094
Leishmania major pyruvate kinase 0.014 0.0264 0.1762
Trypanosoma cruzi beta tubulin, putative 0.0625 0.1426 1
Leishmania major zeta tubulin, putative 0.0498 0.1123 0.7849
Trypanosoma brucei zeta tubulin, putative 0.0498 0.1123 0.7849
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0074 0.0107 0.0268
Echinococcus multilocularis ecdysone induced protein 78C 0.0074 0.0107 0.0094
Loa Loa (eye worm) hypothetical protein 0.0698 0.16 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0039 0.0023 0.0029
Schistosoma mansoni tubulin subunit epsilon 0.0384 0.0848 0.2389
Schistosoma mansoni ap endonuclease 0.0039 0.0023 0.0029
Brugia malayi Niemann-Pick C1 protein precursor 0.0401 0.0889 0.5557
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0142 0.0129
Loa Loa (eye worm) hypothetical protein 0.0092 0.0149 0.0934
Giardia lamblia Pyruvate kinase 0.0072 0.0101 0.0556
Brugia malayi Pyruvate kinase, muscle isozyme 0.014 0.0264 0.1652
Onchocerca volvulus 0.008 0.012 0.148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0074 0.0107 0.0669
Trypanosoma cruzi epsilon tubulin, putative 0.0384 0.0848 0.5904
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0164 0.0323 0.2232
Brugia malayi AMP-binding enzyme family protein 0.0123 0.0224 0.1399
Leishmania major gamma-tubulin 0.0384 0.0849 0.5912
Schistosoma mansoni alpha tubulin 0.0471 0.1057 0.2987
Schistosoma mansoni tubulin subunit alpha 0.0471 0.1057 0.2987
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0123 0.0224 0.6765
Trypanosoma cruzi pyruvate kinase 2, putative 0.014 0.0264 0.1762
Trichomonas vaginalis tubulin alpha chain, putative 0.019 0.0385 0.262
Trypanosoma cruzi tubulin delta chain 0.0363 0.0798 0.5549
Schistosoma mansoni tubulin subunit beta 0.0625 0.1426 0.4041
Echinococcus multilocularis beta tubulin 0.0625 0.1426 0.1415
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0281 0.0602 0.4153
Loa Loa (eye worm) alpha-tubulin 0.0471 0.1057 0.6607
Loa Loa (eye worm) hypothetical protein 0.0036 0.0016 0.0099
Loa Loa (eye worm) tubulin alpha 2 0.031 0.0671 0.4195
Mycobacterium ulcerans cell division protein FtsZ 0.0161 0.0315 0.9744
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Echinococcus granulosus tubulin delta chain 0.0161 0.0315 0.1739
Brugia malayi small heat shock protein 0.0698 0.16 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0161 0.0315 0.2125
Entamoeba histolytica tubulin family protein 0.0625 0.1426 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0123 0.0224 0.6765
Loa Loa (eye worm) hypothetical protein 0.0164 0.0323 0.202
Loa Loa (eye worm) hypothetical protein 0.0074 0.0107 0.0669
Echinococcus granulosus tubulin alpha 0.0351 0.0771 0.4361
Toxoplasma gondii beta tubulin 0.0625 0.1426 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0045 0.0031
Schistosoma mansoni hypothetical protein 0.0166 0.0327 0.0896
Echinococcus granulosus ecdysone induced protein 78C 0.0074 0.0107 0.054
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0023 0.0029
Trypanosoma brucei alpha tubulin 0.0471 0.1057 0.7386
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Trypanosoma cruzi alpha tubulin, putative 0.0471 0.1057 0.7386
Schistosoma mansoni hypothetical protein 0.0048 0.0045 0.009
Schistosoma mansoni hypothetical protein 0.0166 0.0327 0.0896
Echinococcus multilocularis tubulin delta chain 0.0161 0.0315 0.0303
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0023 0.0053
Echinococcus multilocularis beta tubulin 0.0625 0.1426 0.1415
Entamoeba histolytica acyl-CoA synthetase, putative 0.0123 0.0224 0.1475
Echinococcus granulosus pyruvate kinase 0.014 0.0264 0.1445
Loa Loa (eye worm) hypothetical protein 0.0039 0.0023 0.0146
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.006 0.0074 0.0412
Brugia malayi Tubulin beta chain 0.019 0.0385 0.2407
Leishmania major 4-coumarate:coa ligase-like protein 0.0123 0.0224 0.1475
Leishmania major 4-coumarate:coa ligase-like protein 0.0123 0.0224 0.1475
Leishmania major beta tubulin 0.0625 0.1426 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.1426 0.1415
Echinococcus granulosus tubulin alpha chain 0.0471 0.1057 0.6007
Leishmania major beta tubulin 0.0625 0.1426 1
Treponema pallidum phosphoglycerate kinase 0.0164 0.0323 1
Loa Loa (eye worm) hypothetical protein 0.0098 0.0163 0.1019
Echinococcus multilocularis tubulin alpha chain 0.0471 0.1057 0.1046
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0123 0.0224 0.6765
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0023 0.0053
Brugia malayi Phosphoglycerate kinase 0.006 0.0074 0.0463
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0023 0.0146
Trichomonas vaginalis tubulin, putative 0.019 0.0385 0.262
Trichomonas vaginalis tubulin epsilon chain, putative 0.0471 0.1057 0.7386
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.019 0.0385 0.262
Loa Loa (eye worm) hypothetical protein 0.0337 0.0736 0.4598
Loa Loa (eye worm) pyruvate kinase 0.014 0.0264 0.1652
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0158 0.0986
Loa Loa (eye worm) oxidoreductase 0.0036 0.0016 0.0099
Leishmania major beta tubulin 0.0625 0.1426 1
Mycobacterium leprae Probable pyruvate kinase PykA 0.014 0.0264 0.8083
Echinococcus multilocularis expressed conserved protein 0.0376 0.0831 0.0819
Trichomonas vaginalis tubulin, putative 0.0194 0.0394 0.2679
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0023 0.001
Brugia malayi steroid hormone receptor 0.0074 0.0107 0.0669
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0074 0.0107 0.0268
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0137 0.418
Onchocerca volvulus 0.0036 0.0016 0.0037
Mycobacterium ulcerans pyruvate kinase 0.014 0.0264 0.8083
Brugia malayi Steroid receptor seven-up type 2 0.0074 0.0107 0.0669
Trypanosoma brucei beta tubulin 0.0625 0.1426 1
Schistosoma mansoni tubulin subunit beta 0.0625 0.1426 0.4041
Trypanosoma brucei beta tubulin 0.0351 0.0771 0.5358
Loa Loa (eye worm) hypothetical protein 0.0092 0.0149 0.0934
Trichomonas vaginalis tubulin beta chain, putative 0.0625 0.1426 1
Schistosoma mansoni alpha tubulin 0.0471 0.1057 0.2987
Toxoplasma gondii propionate-CoA ligase 0.0036 0.0016 0.0066
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.006 0.0074 0.0412
Echinococcus granulosus tubulin alpha chain 0.0471 0.1057 0.6007
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.005 0.0239
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0074 0.0107 0.0669
Onchocerca volvulus 0.0036 0.0016 0.0037
Brugia malayi CHE-14 protein 0.0172 0.0341 0.2133
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.1426 0.8127
Loa Loa (eye worm) hypothetical protein 0.0036 0.0016 0.0099
Echinococcus granulosus tubulin beta 1 chain 0.0625 0.1426 0.8127
Loa Loa (eye worm) tubulin alpha 2 0.031 0.0671 0.4195
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0023 0.0609
Loa Loa (eye worm) beta-tubulin 0.0625 0.1426 0.8909
Trichomonas vaginalis tubulin alpha chain, putative 0.0351 0.0771 0.5358
Schistosoma mansoni ap endonuclease 0.0039 0.0023 0.0029
Onchocerca volvulus Pyruvate kinase homolog 0.014 0.0264 0.3476
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0044 0.0088
Loa Loa (eye worm) tubulin alpha-3 chain 0.0281 0.0602 0.3758
Echinococcus granulosus jun protein 0.0101 0.0172 0.0916
Plasmodium falciparum tubulin gamma chain 0.0384 0.0849 0.5912
Loa Loa (eye worm) hypothetical protein 0.0074 0.0107 0.0669
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0074 0.0107 0.0094
Mycobacterium ulcerans phosphoglycerate kinase 0.0164 0.0323 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.1426 0.1415
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0074 0.0107 0.0669
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0137 0.418
Leishmania major beta tubulin 0.0625 0.1426 1
Trypanosoma cruzi zeta tubulin, putative 0.0498 0.1123 0.7849
Trichomonas vaginalis tubulin alpha chain, putative 0.019 0.0385 0.262
Plasmodium vivax tubulin gamma chain, putative 0.0384 0.0849 0.5912
Trichomonas vaginalis tubulin gamma chain, putative 0.0384 0.0849 0.5912
Schistosoma mansoni pyruvate kinase 0.014 0.0264 0.0718
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.005 0.0239
Leishmania major beta tubulin 0.0625 0.1426 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0152 0.0294 0.1835
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0315 0.2125
Schistosoma mansoni tubulin subunit alpha 0.0471 0.1057 0.2987
Giardia lamblia Epsilon tubulin 0.0193 0.0392 0.2632
Loa Loa (eye worm) hypothetical protein 0.0471 0.1057 0.6607
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.1426 0.8127
Trypanosoma brucei epsilon tubulin 0.0351 0.0771 0.5358
Entamoeba histolytica tubulin family protein 0.0625 0.1426 1
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0193 0.0392 0.2719
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Loa Loa (eye worm) tubulin beta chain 0.0161 0.0315 0.1971
Brugia malayi Tubulin alpha chain 0.0161 0.0315 0.1971
Leishmania major pyruvate kinase 0.014 0.0264 0.1762
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0123 0.0224 0.6765
Plasmodium falciparum tubulin delta chain, putative 0.0161 0.0315 0.2125
Echinococcus multilocularis pyruvate kinase 0.0072 0.0101 0.0088
Schistosoma mansoni thyroid hormone receptor 0.0074 0.0107 0.0268
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Chlamydia trachomatis pyruvate kinase 0.014 0.0264 0.6611
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0224 0.6765
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0023 0.0242
Brugia malayi nuclear hormone receptor 0.0035 0.0013 0.0083
Giardia lamblia Beta tubulin 0.0625 0.1426 1
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1057 0.7386
Echinococcus granulosus Tubulin alpha 1 chain 0.0471 0.1057 0.6007
Schistosoma mansoni hypothetical protein 0.0166 0.0327 0.0896
Loa Loa (eye worm) pyruvate kinase 0.014 0.0264 0.1652
Schistosoma mansoni patched 1 0.0172 0.0341 0.0939
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1057 0.7386
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0045 0.0031
Loa Loa (eye worm) steroid hormone receptor 0.0074 0.0107 0.0669
Plasmodium vivax delta tubulin, putative 0.0161 0.0315 0.2125
Schistosoma mansoni hypothetical protein 0.0048 0.0045 0.009
Echinococcus granulosus Tubulin alpha 1 chain 0.0471 0.1057 0.6007
Echinococcus multilocularis tubulin alpha chain 0.0471 0.1057 0.1046
Echinococcus granulosus tubulin alpha 3 chain 0.0471 0.1057 0.6007
Trypanosoma brucei epsilon tubulin 0.0384 0.0848 0.5904
Loa Loa (eye worm) alpha-tubulin isotype 2 0.031 0.0671 0.4195
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0074 0.0107 0.054
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.031 0.0671 0.4649
Loa Loa (eye worm) BEN-1 protein 0.0625 0.1426 0.8909
Plasmodium falciparum alpha tubulin 1 0.0471 0.1057 0.7386
Echinococcus multilocularis geminin 0.0528 0.1194 0.1183
Schistosoma mansoni jun-related protein 0.0082 0.0127 0.0325
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0363 0.0798 0.5578
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0074 0.0107 0.0669
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0023 0.0146
Echinococcus multilocularis tubulin beta 1 chain 0.0625 0.1426 0.1415
Echinococcus granulosus tubulin epsilon chain 0.0384 0.0848 0.4805
Schistosoma mansoni hypothetical protein 0.0048 0.0045 0.009
Brugia malayi Tubulin alpha-2 chain 0.0471 0.1057 0.6607
Trichomonas vaginalis tubulin beta chain, putative 0.019 0.0385 0.262
Mycobacterium ulcerans hypothetical protein 0.0123 0.0224 0.6765
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0074 0.0107 0.0669
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.005 0.0239
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1057 0.7386
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0036 0.0016 0.0376
Plasmodium vivax tubulin beta chain, putative 0.0625 0.1426 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0158 0.0414
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0074 0.0107 0.0268
Echinococcus multilocularis Niemann Pick C1 protein 0.0401 0.0889 0.0877
Leishmania major beta tubulin 0.0625 0.1426 1
Brugia malayi nuclear receptor RXR 0.0039 0.0023 0.0146
Echinococcus granulosus pyruvate kinase 0.0072 0.0101 0.0507
Loa Loa (eye worm) tubulin beta chain 0.0625 0.1426 0.8909
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0074 0.0107 0.0669
Echinococcus granulosus pyruvate kinase 0.0072 0.0101 0.0507
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.014 0.0264 0.8155
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0016 0.0099
Trypanosoma brucei phosphoglycerate kinase 0.006 0.0074 0.0412
Echinococcus multilocularis FTZ F1 alpha 0.0074 0.0107 0.0094
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1057 0.7386
Brugia malayi conserved hypotetical protein 0.0035 0.0013 0.0083
Trypanosoma brucei beta tubulin 0.0625 0.1426 1
Entamoeba histolytica phosphoglycerate kinase, putative 0.0164 0.0323 0.2181
Brugia malayi nuclear hormone receptor 0.0074 0.0107 0.0669
Trichomonas vaginalis tubulin epsilon chain, putative 0.0471 0.1057 0.7386
Onchocerca volvulus 0.0048 0.0044 0.0424
Schistosoma mansoni tubulin subunit beta 0.0161 0.0315 0.0864
Schistosoma mansoni tubulin subunit alpha 0.0161 0.0315 0.0864
Brugia malayi hypothetical protein 0.0039 0.0023 0.0146
Schistosoma mansoni tubulin subunit alpha 0.0471 0.1057 0.2987
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0158 0.0414
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0161 0.0315 0.9737
Brugia malayi AMP-binding enzyme family protein 0.0123 0.0224 0.1399
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0016 0.0099
Entamoeba histolytica tubulin alpha chain, putative 0.0471 0.1057 0.7386
Trichomonas vaginalis pyruvate kinase, putative 0.014 0.0264 0.1762
Brugia malayi hypothetical protein 0.0146 0.028 0.1751
Trichomonas vaginalis tubulin epsilon chain, putative 0.0625 0.1426 1
Leishmania major beta tubulin 0.0625 0.1426 1
Brugia malayi nuclear receptor NHR-88 0.0035 0.0013 0.0083
Trypanosoma brucei alpha tubulin, putative 0.019 0.0385 0.262
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0152 0.0294 0.1835
Echinococcus granulosus tubulin alpha chain 0.0471 0.1057 0.6007
Loa Loa (eye worm) tubulin alpha chain 0.0471 0.1057 0.6607
Brugia malayi hypothetical protein 0.0035 0.0013 0.0083
Echinococcus multilocularis pyruvate kinase 0.0072 0.0101 0.0088
Leishmania major beta tubulin 0.0625 0.1426 1
Loa Loa (eye worm) BEN-1 protein 0.0625 0.1426 0.8909
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0158 0.0832
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.005 0.0239
Giardia lamblia Beta tubulin 0.0625 0.1426 1
Brugia malayi Pyruvate kinase, M2 isozyme 0.014 0.0264 0.1652
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Echinococcus granulosus tubulin beta 4A class IVa 0.0625 0.1426 0.8127
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0164 0.0323 0.2181
Leishmania major epsilon tubulin, putative 0.0384 0.0848 0.5904
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0158 0.0986
Brugia malayi nuclear receptor NHR-67 0.0035 0.0013 0.0083
Echinococcus multilocularis pyruvate kinase 0.014 0.0264 0.0251
Trichomonas vaginalis tubulin, putative 0.019 0.0385 0.262
Plasmodium vivax phosphoglycerate kinase, putative 0.0164 0.0323 0.2181
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0341 0.2309
Schistosoma mansoni coup transcription factor 0.0074 0.0107 0.0268
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0123 0.0224 0.6886
Plasmodium vivax tubulin alpha chain, putative 0.0471 0.1057 0.7386
Trypanosoma brucei alpha tubulin 0.0471 0.1057 0.7386
Leishmania major delta tubulin, putative 0.0363 0.0798 0.5549
Echinococcus granulosus tubulin subunit beta 0.0625 0.1426 0.8127
Loa Loa (eye worm) hypothetical protein 0.0401 0.0889 0.5557
Trypanosoma brucei pyruvate kinase 1, putative 0.014 0.0264 0.1762
Onchocerca volvulus 0.019 0.0385 0.5149
Plasmodium vivax tubulin epsilon chain, putative 0.0384 0.0848 0.5904
Brugia malayi hypothetical protein 0.0035 0.0013 0.0083
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0042 0.0031 0.0192
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Trypanosoma brucei alpha tubulin 0.0471 0.1057 0.7386
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0016 0.0376
Echinococcus multilocularis pyruvate kinase 0.0072 0.0101 0.0088
Echinococcus granulosus sterol regulatory element binding protein 0.0172 0.0341 0.1888
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Brugia malayi nuclear hormone receptor family member odr-7 0.0035 0.0013 0.0083
Echinococcus multilocularis tubulin alpha chain 0.0471 0.1057 0.1046
Echinococcus multilocularis sterol regulatory element binding protein 0.0172 0.0341 0.0329
Trypanosoma cruzi tubulin delta chain 0.0363 0.0798 0.5549
Echinococcus multilocularis tubulin alpha 0.0351 0.0771 0.0759
Trichomonas vaginalis tubulin alpha chain, putative 0.019 0.0385 0.262
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0035 0.0013 0.0083
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0074 0.0107 0.0669
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0158 0.0145
Echinococcus multilocularis jun protein 0.0101 0.0172 0.0159
Loa Loa (eye worm) hypothetical protein 0.014 0.0264 0.1652
Echinococcus multilocularis peroxisome assembly protein 26 0.0471 0.1057 0.1046
Plasmodium falciparum tubulin epsilon chain, putative 0.0384 0.0848 0.5904
Schistosoma mansoni ADP-ribosyl cyclase 0.1494 0.3509 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0407 0.0904 0.2549
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0158 0.0832
Loa Loa (eye worm) hypothetical protein 0.0099 0.0166 0.1035
Brugia malayi Nuclear hormone receptor E75 0.0035 0.0013 0.0083
Toxoplasma gondii alpha tubulin TUBA1 0.0471 0.1057 0.7404
Loa Loa (eye worm) hypothetical protein 0.031 0.0671 0.4195
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0074 0.0107 0.0094
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0036 0.0016 0.0376
Brugia malayi tubulin alpha-2 chain 0.0471 0.1057 0.6607
Trypanosoma cruzi phosphoglycerate kinase, putative 0.006 0.0074 0.0412
Treponema pallidum cell division protein FtsZ 0.0161 0.0315 0.9737
Leishmania major 4-coumarate:coa ligase-like protein 0.0123 0.0224 0.1475
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1057 0.7386
Loa Loa (eye worm) hypothetical protein 0.0074 0.0107 0.0669
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0023 0.0053
Leishmania major beta tubulin 0.0625 0.1426 1
Brugia malayi tailless protein 0.0035 0.0013 0.0083
Brugia malayi hypothetical protein 0.0337 0.0736 0.4598
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0036 0.0016 0.0376
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0023 0.0053
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0224 0.6765
Loa Loa (eye worm) tubulin alpha chain 0.0471 0.1057 0.6607
Echinococcus granulosus peroxisome assembly protein 26 0.0471 0.1057 0.6007
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.0178 0.1115
Trichomonas vaginalis pyruvate kinase, putative 0.014 0.0264 0.1762
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0023 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0315 0.2125
Echinococcus multilocularis microtubule associated protein 2 0.0761 0.1751 0.174
Onchocerca volvulus 0.0074 0.0107 0.1299
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.1057 0.7386
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0016 0.0099
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0158 0.0414
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0016 0.0099
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.1426 0.1415
Loa Loa (eye worm) hypothetical protein 0.005 0.005 0.031
Echinococcus granulosus tubulin gamma 1 chain 0.0384 0.0849 0.4811
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.1426 0.8127
Echinococcus multilocularis Tubulin alpha 1 chain 0.0471 0.1057 0.1046
Echinococcus granulosus Tubulin alpha 1 chain 0.0471 0.1057 0.6007
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0092 0.0149 0.4344
Loa Loa (eye worm) tubulin alpha 2 0.0119 0.0215 0.1346
Brugia malayi Phosphoglycerate kinase 0.0164 0.0323 0.202
Entamoeba histolytica hypothetical protein 0.0146 0.028 0.1875
Loa Loa (eye worm) hypothetical protein 0.0281 0.0602 0.3758
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.005 0.0239
Giardia lamblia Alpha-tubulin 0.0471 0.1057 0.7373
Echinococcus multilocularis protein dispatched 1 0.0196 0.04 0.0387
Leishmania major hypothetical protein, conserved 0.005 0.005 0.0239
Trypanosoma brucei epsilon tubulin 0.0384 0.0848 0.5904
Entamoeba histolytica pyruvate kinase, putative 0.0098 0.0163 0.1044
Echinococcus granulosus expressed conserved protein 0.0376 0.0831 0.4706
Echinococcus multilocularis hypothetical protein 0.0471 0.1057 0.1046
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0161 0.0315 0.2125
Echinococcus granulosus tubulin alpha 1C chain 0.0471 0.1057 0.6007
Brugia malayi Calcitonin receptor-like protein seb-1 0.0152 0.0294 0.1835
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0172 0.0341 0.2133
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0023 0.0053
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.005 0.0239
Echinococcus granulosus pyruvate kinase 0.014 0.0264 0.1445
Trypanosoma cruzi tubulin gamma chain 0.0384 0.0849 0.5912
Brugia malayi hypothetical protein 0.005 0.005 0.031
Echinococcus granulosus beta tubulin 0.0625 0.1426 0.8127
Trypanosoma cruzi pyruvate kinase 2, putative 0.014 0.0264 0.1762
Trypanosoma brucei pyruvate kinase 1 0.014 0.0264 0.1762
Loa Loa (eye worm) pyruvate kinase-PB 0.0098 0.0163 0.1019
Brugia malayi beta-tubulin, identical 0.0625 0.1426 0.8909
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0023 0.0146
Loa Loa (eye worm) hypothetical protein 0.0074 0.0107 0.0669
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0471 0.1057 0.7386
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0137 0.418
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0016 0.0376
Brugia malayi alpha-tubulin 0.0471 0.1057 0.6607
Leishmania major beta tubulin 0.0625 0.1426 1
Plasmodium falciparum pyruvate kinase 0.014 0.0264 0.1762
Trichomonas vaginalis tubulin epsilon chain, putative 0.0625 0.1426 1
Loa Loa (eye worm) tubulin beta-1 chain 0.0625 0.1426 0.8909
Schistosoma mansoni hypothetical protein 0.0528 0.1194 0.3378
Loa Loa (eye worm) hypothetical protein 0.0211 0.0434 0.2712
Brugia malayi hypothetical protein 0.0039 0.0023 0.0146
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0164 0.0323 1
Schistosoma mansoni hypothetical protein 0.0048 0.0045 0.009
Echinococcus granulosus pyruvate kinase 0.0072 0.0101 0.0507
Toxoplasma gondii alpha-tubulin I, putative 0.0471 0.1057 0.7404
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0074 0.0107 0.0669
Loa Loa (eye worm) hypothetical protein 0.0074 0.0107 0.0669
Echinococcus multilocularis tubulin epsilon chain 0.0384 0.0848 0.0836
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0123 0.0224 0.6765
Brugia malayi MH2 domain containing protein 0.0122 0.0221 0.1382
Echinococcus multilocularis phosphoglycerate kinase 1 0.0164 0.0323 0.0311
Schistosoma mansoni hypothetical protein 0.0104 0.0178 0.0473
Onchocerca volvulus 0.0036 0.0016 0.0037
Echinococcus granulosus Niemann Pick C1 protein 0.0401 0.0889 0.5041
Leishmania major beta tubulin 0.0625 0.1426 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0074 0.0107 0.0669
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0074 0.0107 0.0268
Loa Loa (eye worm) hypothetical protein 0.0048 0.0044 0.0274
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0123 0.0224 0.6886
Echinococcus multilocularis Niemann Pick C1 protein 0.0573 0.1301 0.129
Toxoplasma gondii pyruvate kinase PyKII 0.0072 0.0101 0.0669
Echinococcus granulosus Protein patched homolog 1 0.0172 0.0341 0.1888
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0016 0.0099
Echinococcus multilocularis protein patched 0.0172 0.0341 0.0329
Echinococcus granulosus tumor protein p63 0.0326 0.0711 0.4017
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0036 0.0016 0.0099
Giardia lamblia Delta tubulin 0.0161 0.0315 0.2083
Brugia malayi Tubulin alpha-2 chain 0.0471 0.1057 0.6607
Echinococcus granulosus tubulin alpha 3 chain 0.0471 0.1057 0.6007
Trypanosoma brucei beta tubulin 0.0625 0.1426 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0158 0.0145
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Loa Loa (eye worm) pyruvate kinase 0.014 0.0264 0.1652
Loa Loa (eye worm) hypothetical protein 0.0123 0.0224 0.1399
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Leishmania major beta tubulin 0.0625 0.1426 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Schistosoma mansoni nuclear hormone receptor 0.0074 0.0107 0.0268
Loa Loa (eye worm) DR-78 0.0035 0.0013 0.0083
Entamoeba histolytica acyl-coA synthetase, putative 0.0123 0.0224 0.1475
Echinococcus multilocularis tubulin gamma 1 chain 0.0384 0.0849 0.0837
Plasmodium falciparum phosphoglycerate kinase 0.0164 0.0323 0.2181
Brugia malayi Cell division protein ftsZ 0.0161 0.0315 0.1971
Leishmania major alpha tubulin 0.0471 0.1057 0.7386
Brugia malayi tubulin alpha chain - mouse 0.0471 0.1057 0.6607
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.006 0.0074 0.0412
Schistosoma mansoni pyruvate kinase 0.0072 0.0101 0.0252
Brugia malayi Tubulin beta chain 0.0161 0.0315 0.1971
Loa Loa (eye worm) hypothetical protein 0.0039 0.0023 0.0146
Echinococcus granulosus phosphoglycerate kinase 1 0.0164 0.0323 0.1784
Echinococcus granulosus tubulin alpha 1C chain 0.0471 0.1057 0.6007
Trichomonas vaginalis tubulin gamma chain, putative 0.0384 0.0848 0.5904
Loa Loa (eye worm) hypothetical protein 0.0074 0.0107 0.0669
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0101 0.0172 0.0159
Plasmodium falciparum acyl-CoA synthetase 0.0092 0.0149 0.0947
Onchocerca volvulus Bile acid receptor homolog 0.0074 0.0107 0.1299
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0083
Plasmodium falciparum alpha tubulin 2 0.0471 0.1057 0.7386
Entamoeba histolytica tubulin alpha-1 chain 0.0471 0.1057 0.7386
Leishmania major beta tubulin 0.0625 0.1426 1
Echinococcus granulosus microtubule associated protein 2 0.0761 0.1751 1
Brugia malayi Tubulin gamma chain 0.0384 0.0849 0.5308
Onchocerca volvulus 0.0337 0.0736 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0074 0.0107 0.054
Brugia malayi Nuclear hormone receptor E75 0.0035 0.0013 0.0083
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0123 0.0224 0.6765
Trypanosoma cruzi epsilon tubulin, putative 0.0384 0.0848 0.5904
Schistosoma mansoni tubulin subunit beta 0.0625 0.1426 0.4041
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0016 0.0376
Brugia malayi Nuclear hormone receptor-like 1 0.0074 0.0107 0.0669
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0164 0.0323 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0074 0.0107 0.0268
Entamoeba histolytica tubulin gamma chain 0.0384 0.0849 0.5912
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0045 0.0181
Brugia malayi ecdysone receptor 0.0035 0.0013 0.0083
Chlamydia trachomatis phosphoglycerate kinase 0.0164 0.0323 1
Giardia lamblia Alpha-tubulin 0.0471 0.1057 0.7373
Schistosoma mansoni tubulin subunit beta 0.0625 0.1426 0.4041
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0164 0.0323 0.2181
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.1426 0.8127
Trichomonas vaginalis tubulin alpha chain, putative 0.0625 0.1426 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0045 0.0279

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Trypanocidal activity against Trypanosoma brucei brucei s427 measured within 6 hrs by propidium iodide staining-based fluorimetric analysis ChEMBL. 26231081
Activity (binding) Irreversible binding affinity to PDI catalytic domain a (unknown origin) at 3 mM measured after 100 fold dilution for 2 hrs by intrinsic tryptophan fluorescence assay ChEMBL. 26500720
CC50 (ADMET) = 0.32 uM Cytotoxicity against HEK293T cells after 30 hrs by Alamar Blue assay ChEMBL. 26231081
EC50 (functional) = 0.00045 uM Antitrypanosomal activity against TbAt1-deficient bloodstraem form of Trypanosoma brucei brucei 427 (BS221) after 72 hrs by alamar blue assay ChEMBL. 24900279
EC50 (functional) = 0.00066 uM Antitrypanosomal activity against bloodstream form of Trypanosoma brucei brucei 427 (BS221) after 72 hrs by alamar blue assay ChEMBL. 24900279
EC50 (functional) = 0.0013 uM Antitrypanosomal activity against TbAt1-deficient bloodstraem form Trypanosoma brucei brucei B48 after 72 hrs by alamar blue assay ChEMBL. 24900279
EC50 (ADMET) = 6.4 uM Cytotoxicity against human HEK293T cells after 72 hrs by alamar blue assay ChEMBL. 24900279
Potency (functional) 0.3064 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.3467 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.4856 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.4897 uM PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.6917 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.0962 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.9167 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.7606 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 24900279
Trypanosoma brucei gambiense 24900279

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Targets
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 26882  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 26953  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 29919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 25756  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 29777  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 25113  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 29099  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 28601  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 24472  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 21739  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 28044  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 21309  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 24440  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 20919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 22594  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 23453  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 21545  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 29554  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 29031  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 23905  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 21179  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 25450  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 22205  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 27459  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 26961  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 22252  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 23996  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 23078  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 20827  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 28024  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 28324  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 26882  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 26953  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 29919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 25756  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 29777  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 25113  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 29099  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 28601  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 24472  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 21739  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 28044  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 21309  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 24440  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 20919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 22594  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 23453  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 21545  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 29554  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 29031  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 23905  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 21179  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 25450  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 22205  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 27459  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 26961  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 22252  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 23996  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 23078  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 20827  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 28024  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania amazonensis 28324  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 10029309

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

5 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.