Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0062 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0062 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0062 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0062 | 1 | 0.5 |
Onchocerca volvulus | 0.0062 | 1 | 0.5 | |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0062 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0062 | 1 | 0.5 |
Onchocerca volvulus | 0.0062 | 1 | 0.5 | |
Loa Loa (eye worm) | oxidoreductase | 0.0062 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0062 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0062 | 1 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0062 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0062 | 1 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0062 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0062 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0062 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0062 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0062 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0062 | 1 | 0.5 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0062 | 1 | 0.5 |
Onchocerca volvulus | 0.0062 | 1 | 0.5 | |
Echinococcus granulosus | aldo keto reductase | 0.0062 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0062 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0062 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0062 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0062 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Schistosoma mansoni | pol-related | 0.0062 | 1 | 0.5 |
Onchocerca volvulus | 0.0062 | 1 | 0.5 | |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0062 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0062 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0062 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0062 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0062 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0062 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0062 | 1 | 0.5 |
Onchocerca volvulus | 0.0062 | 1 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0062 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Toxoplasma gondii | aldose reductase, putative | 0.0062 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0062 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0062 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0062 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0062 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 1 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0062 | 1 | 0.5 |
Trypanosoma cruzi | aldo-keto reductase | 0.0062 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0062 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 1 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0062 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
logKd (ADMET) | = 4.78 | Binding affinity to bovine serum albumin by circular dichroic probe technique | ChEMBL. | 576620 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.