Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0018 | 0.0012 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0111 | 0.0264 |
Echinococcus multilocularis | acetylcholinesterase | 0.0667 | 0.4079 | 0.4075 |
Echinococcus granulosus | acetylcholinesterase | 0.0667 | 0.4079 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0218 | 0.0519 |
Onchocerca volvulus | 0.0049 | 0.0265 | 0.3719 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0006 | 0.0015 |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.0067 | 0.0374 | 0.0917 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0024 | 0.0319 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0113 | 0.0658 | 0.1778 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0081 | 0.0187 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0113 | 0.0658 | 0.1601 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.001 | 0.0024 | 0.032 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0153 | 0.036 |
Onchocerca volvulus | 0.0007 | 0.0006 | 0.0087 | |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0081 | 0.0074 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0111 | 0.438 |
Brugia malayi | Carboxylesterase family protein | 0.0113 | 0.0658 | 0.1613 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0074 | 0.018 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0046 | 0.0246 | 0.024 |
Schistosoma mansoni | amine oxidase | 0.0046 | 0.0246 | 0.0588 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.001 | 0.0024 | 0.0754 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.0024 | 0.032 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0006 | 0.0015 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0188 | 0.0461 |
Onchocerca volvulus | 0.0007 | 0.0006 | 0.0087 | |
Brugia malayi | Matrixin family protein | 0.0055 | 0.0301 | 0.0737 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0081 | 0.0197 |
Brugia malayi | Matrixin family protein | 0.0055 | 0.0301 | 0.0737 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 1 |
Schistosoma mansoni | gliotactin | 0.0113 | 0.0658 | 0.1601 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0344 | 0.083 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.025 | 0.0599 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0081 | 0.3103 |
Mycobacterium ulcerans | monoamine oxidase | 0.0046 | 0.0246 | 0.0602 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.024 | 0.1444 | 0.3531 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0081 | 0.0074 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.001 | 0.0024 | 0.0491 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0007 | 0.0006 | 0.0015 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0188 | 0.0182 |
Onchocerca volvulus | 0.0007 | 0.0006 | 0.0087 | |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.0231 | 0.3469 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0188 | 0.3171 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0143 | 0.0349 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0068 | 0.0182 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0188 | 0.0446 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0046 | 0.0246 | 1 |
Treponema pallidum | DNA ligase (lig) | 0.001 | 0.0024 | 0.5 |
Schistosoma mansoni | topbp1 | 0.001 | 0.0024 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0246 | 0.0603 |
Onchocerca volvulus | Matrilysin homolog | 0.0121 | 0.0712 | 1 |
Schistosoma mansoni | DNA ligase IV | 0.001 | 0.0024 | 0.0044 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.0006 | 0.0015 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0113 | 0.0658 | 0.1601 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0148 | 0.0874 | 0.0868 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.0081 | 0.1297 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0081 | 0.1179 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0007 | 0.0006 | 0.0016 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0081 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.0902 | 0.221 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0113 | 0.0658 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0046 | 0.0246 | 0.0602 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0301 | 0.0737 |
Onchocerca volvulus | 0.0055 | 0.0301 | 0.422 | |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0007 | 0.0003 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0046 | 0.0246 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0081 | 0.0197 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0111 | 0.0264 |
Echinococcus granulosus | geminin | 0.0181 | 0.1083 | 0.2643 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0046 | 0.0246 | 0.0603 |
Brugia malayi | DKFZp564C0469 protein | 0.001 | 0.0024 | 0.006 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.0111 | 0.183 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0046 | 0.0246 | 0.0602 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0227 | 0.0557 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0658 | 0.1613 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.0231 | 0.7075 |
Brugia malayi | Carboxylesterase family protein | 0.0113 | 0.0658 | 0.1613 |
Loa Loa (eye worm) | carboxylesterase | 0.0113 | 0.0658 | 0.1613 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0415 | 0.2525 | 0.2521 |
Brugia malayi | hypothetical protein | 0.0121 | 0.0711 | 0.1744 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0006 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0227 | 0.0557 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0046 | 0.0246 | 0.651 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0111 | 0.03 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0111 | 0.438 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0046 | 0.0246 | 0.024 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0046 | 0.0246 | 0.0588 |
Brugia malayi | Carboxylesterase family protein | 0.0113 | 0.0658 | 0.1613 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0265 | 0.0649 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0024 | 0.006 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0111 | 0.0264 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0055 | 0.0301 | 0.0723 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0246 | 0.0603 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0046 | 0.0246 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.0231 | 0.7075 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0188 | 0.0446 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.0231 | 0.0551 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0074 | 0.2994 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0006 | 0.0016 |
Onchocerca volvulus | Huntingtin homolog | 0.0121 | 0.0711 | 0.999 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0068 | 0.0182 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.0044 | 0.5075 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0579 | 0.1421 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 0.3103 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.0208 | 0.8471 |
Onchocerca volvulus | 0.0029 | 0.0143 | 0.2002 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0024 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0074 | 0.018 |
Echinococcus multilocularis | muscleblind protein | 0.0152 | 0.0902 | 0.0896 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0068 | 0.0182 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.0326 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0113 | 0.0658 | 0.1601 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0148 | 0.0874 | 0.213 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0046 | 0.0246 | 0.0664 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.025 | 0.0244 |
Loa Loa (eye worm) | matrixin family protein | 0.0132 | 0.078 | 0.1912 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0111 | 0.438 |
Echinococcus granulosus | carboxylesterase 5A | 0.0667 | 0.4079 | 1 |
Brugia malayi | hypothetical protein | 0.0113 | 0.0658 | 0.1613 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0265 | 0.0635 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0227 | 0.0543 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0046 | 0.0246 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0658 | 0.1613 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0007 | 0.0006 | 0.0016 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0113 | 0.0658 | 0.1601 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0101 | 0.0589 | 0.1431 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0111 | 0.0264 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.001 | 0.0024 | 0.0315 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0111 | 0.0272 |
Brugia malayi | Matrixin family protein | 0.0055 | 0.0301 | 0.0737 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0046 | 0.0246 | 0.0588 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.0006 | 0.0015 |
Onchocerca volvulus | 0.0078 | 0.0442 | 0.6203 | |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0246 | 0.0603 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0143 | 0.0335 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0658 | 0.1613 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0442 | 0.1069 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0006 | 0.0015 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.01 | 0.0579 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0111 | 0.183 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0046 | 0.0246 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0188 | 0.3171 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0081 | 0.3059 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.001 | 0.0024 | 0.0044 |
Echinococcus multilocularis | nibrin | 0.001 | 0.0024 | 0.0018 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.001 | 0.0024 | 0.0045 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0227 | 0.0543 |
Echinococcus multilocularis | expressed conserved protein | 0.0094 | 0.0542 | 0.0536 |
Loa Loa (eye worm) | STAT protein | 0.0133 | 0.0787 | 0.1929 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0074 | 0.0169 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.1083 | 0.2643 |
Toxoplasma gondii | ATPase, AAA family protein | 0.001 | 0.0024 | 0.0745 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.025 | 0.0244 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0081 | 0.0183 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 0.3103 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0024 | 0.006 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0111 | 0.2852 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0006 | 0.0015 |
Loa Loa (eye worm) | carboxylesterase | 0.0113 | 0.0658 | 0.1613 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.025 | 0.0599 |
Onchocerca volvulus | Matrilysin homolog | 0.0055 | 0.0301 | 0.422 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0218 | 0.0519 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0048 | 0.0257 | 0.7879 |
Brugia malayi | Carboxylesterase family protein | 0.0113 | 0.0658 | 0.1613 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0188 | 0.3171 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0111 | 0.183 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0081 | 0.1179 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0018 | 0.0045 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.0231 | 0.938 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0651 | 0.3984 | 1 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0007 | 0.0006 | 0.0191 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.01 | 0.0579 | 0.1408 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.0208 | 1 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0199 | 0.1191 | 0.291 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0111 | 0.0272 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.001 | 0.0024 | 0.0754 |
Onchocerca volvulus | Huntingtin homolog | 0.0121 | 0.0711 | 0.999 |
Schistosoma mansoni | acetylcholinesterase | 0.0113 | 0.0658 | 0.1601 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0007 | 0.0006 | 0.0253 |
Loa Loa (eye worm) | hypothetical protein | 0.024 | 0.1444 | 0.3541 |
Entamoeba histolytica | hypothetical protein | 0.001 | 0.0024 | 0.0315 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0246 | 0.0603 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0007 | 0.0006 | 0.0016 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0044 | 0.5075 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0024 | 0.006 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0007 | 0.0003 |
Onchocerca volvulus | 0.0024 | 0.0111 | 0.1561 | |
Echinococcus granulosus | muscleblind protein | 0.0152 | 0.0902 | 0.2198 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0111 | 0.0272 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0046 | 0.0246 | 0.7543 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0111 | 0.0264 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0007 | 0.0006 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0711 | 0.1744 |
Schistosoma mansoni | amine oxidase | 0.0046 | 0.0246 | 0.0588 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.001 | 0.0024 | 0.0745 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.0208 | 0.3524 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0227 | 0.0221 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0667 | 0.4079 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0024 | 0.006 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0081 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0667 | 0.4079 | 1 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0227 | 0.0543 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.025 | 0.0613 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0024 | 0.006 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.024 | 0.1444 | 0.1439 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0374 | 0.0917 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0111 | 0.0272 |
Onchocerca volvulus | 0.0113 | 0.0658 | 0.9242 | |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0227 | 0.0221 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0068 | 0.0182 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0046 | 0.0246 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0667 | 0.4079 | 1 |
Toxoplasma gondii | propionate-CoA ligase | 0.0007 | 0.0006 | 0.0191 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0113 | 0.0658 | 0.0652 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0007 | 0.0001 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0007 | 0.0006 | 0.0016 |
Echinococcus granulosus | expressed conserved protein | 0.0094 | 0.0542 | 0.1316 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0113 | 0.0658 | 0.0652 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0081 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0113 | 0.0658 | 0.1601 |
Brugia malayi | topoisomerase | 0.001 | 0.0024 | 0.006 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.0024 | 0.032 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0081 | 0.3103 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0007 | 0.0006 | 0.0191 |
Loa Loa (eye worm) | acetyltransferase | 0.0148 | 0.0874 | 0.2142 |
Brugia malayi | hypothetical protein | 0.024 | 0.1444 | 0.3541 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 0.3103 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.001 | 0.0024 | 0.006 |
Onchocerca volvulus | 0.0007 | 0.0006 | 0.0087 | |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0111 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0246 | 0.0603 |
Mycobacterium ulcerans | hydrolase | 0.0067 | 0.0374 | 0.0925 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0081 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0188 | 0.3171 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0658 | 0.1613 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0006 | 0.0043 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.025 | 0.0599 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0199 | 0.1191 | 0.1186 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0046 | 0.0246 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.0902 | 0.221 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0006 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0658 | 0.1613 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0111 | 0.0264 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0111 | 0.0264 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0024 | 0.0319 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0143 | 0.0848 | 0.2067 |
Brugia malayi | Matrixin family protein | 0.0055 | 0.0301 | 0.0737 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0121 | 0.0712 | 1 |
Brugia malayi | hypothetical protein | 0.001 | 0.0024 | 0.006 |
Echinococcus granulosus | acetylcholinesterase | 0.0667 | 0.4079 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0006 | 0.0043 |
Wolbachia endosymbiont of Brugia malayi | NAD-dependent DNA ligase, Lig | 0.001 | 0.0024 | 0.5 |
Echinococcus multilocularis | neuroligin | 0.0113 | 0.0658 | 0.0652 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0111 | 0.2852 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0667 | 0.4079 | 0.4075 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.1083 | 0.2643 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0113 | 0.0658 | 0.1601 |
Loa Loa (eye worm) | carboxylesterase | 0.0667 | 0.4079 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0081 | 0.0183 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0651 | 0.3984 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0074 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0667 | 0.4079 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0007 | 0.0003 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0605 | 0.3701 | 1 |
Loa Loa (eye worm) | matrix metalloproteinase | 0.0055 | 0.0301 | 0.0737 |
Onchocerca volvulus | 0.0113 | 0.0658 | 0.9242 | |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0143 | 0.0844 | 0.0839 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.001 | 0.0024 | 0.2431 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0111 | 0.0272 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.0044 | 0.5075 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0658 | 0.1613 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0218 | 0.0519 |
Echinococcus granulosus | nibrin | 0.001 | 0.0024 | 0.0044 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0113 | 0.0658 | 0.0652 |
Onchocerca volvulus | 0.0113 | 0.0658 | 0.9242 | |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0111 | 0.03 |
Loa Loa (eye worm) | matrixin family protein | 0.0121 | 0.0712 | 0.1746 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0301 | 0.0737 |
Echinococcus multilocularis | geminin | 0.0181 | 0.1083 | 0.1077 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0153 | 0.0147 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0074 | 0.2226 |
Schistosoma mansoni | topbp1 | 0.001 | 0.0024 | 0.0044 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0024 | 0.0319 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.001 | 0.0024 | 0.0018 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0007 | 0.0006 | 0.0015 |
Brugia malayi | Carboxylesterase family protein | 0.0667 | 0.4079 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 0.3103 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0143 | 0.0349 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0188 | 0.0446 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0046 | 0.0246 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0143 | 0.0844 | 0.2058 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0046 | 0.0246 | 0.0588 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0113 | 0.0658 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0081 | 0.0183 |
Onchocerca volvulus | 0.0113 | 0.0658 | 0.9242 | |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0046 | 0.0246 | 0.0664 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0265 | 0.0259 |
Echinococcus multilocularis | acetylcholinesterase | 0.0667 | 0.4079 | 0.4075 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0218 | 0.0519 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0044 | 0.5075 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0246 | 0.0603 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0148 | 0.0874 | 0.2142 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0081 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0153 | 0.036 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0074 | 0.2994 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0081 | 0.3103 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0246 | 0.0603 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0081 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0711 | 0.1744 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0111 | 0.0264 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0113 | 0.0658 | 0.1778 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.001 | 0.0024 | 0.0754 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0081 | 0.0197 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.025 | 0.0613 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0024 | 0.006 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0007 | 0.0001 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.025 | 0.0599 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0081 | 0.0183 |
Leishmania major | UDP-galactopyranose mutase | 0.0046 | 0.0246 | 1 |
Mycobacterium tuberculosis | Probable peptidoglycan hydrolase | 0.0067 | 0.0374 | 0.1011 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0081 | 0.0187 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0018 | 0.0043 |
Echinococcus granulosus | neuroligin | 0.0113 | 0.0658 | 0.1601 |
Schistosoma mansoni | hypothetical protein | 0.0415 | 0.2525 | 0.6186 |
Brugia malayi | SWIRM domain containing protein | 0.0046 | 0.0246 | 0.0603 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 0.3103 |
Echinococcus granulosus | dnaJ subfamily B | 0.0415 | 0.2525 | 0.6186 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.001 | 0.0024 | 0.006 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0081 | 0.0183 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0081 | 0.0217 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0081 | 0.0183 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0113 | 0.0658 | 0.1778 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0658 | 0.1613 |
Mycobacterium leprae | PROBABLE HYDROLASE | 0.0067 | 0.0374 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0074 | 0.018 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.008 | 0.0457 | 0.1106 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0006 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0074 | 0.018 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.01 | 0.0579 | 0.1421 |
Mycobacterium ulcerans | dehydrogenase | 0.0046 | 0.0246 | 0.0602 |
Brugia malayi | Matrixin family protein | 0.0132 | 0.078 | 0.1912 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0153 | 0.036 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0265 | 0.0635 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.0231 | 0.3469 |
Loa Loa (eye worm) | hypothetical protein | 0.0667 | 0.4079 | 1 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0227 | 0.0557 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0046 | 0.0246 | 1 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.001 | 0.0024 | 0.0988 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0007 | 0.0006 | 0.0016 |
Brugia malayi | Hemopexin family protein | 0.0078 | 0.0442 | 0.1083 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0007 | 0.0006 | 0.0253 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0007 | 0.0006 | 0.0016 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0081 | 1 |
Onchocerca volvulus | 0.0113 | 0.0658 | 0.9242 | |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0113 | 0.0658 | 0.1639 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0133 | 0.0787 | 0.1929 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0081 | 0.0074 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0007 | 0.0006 | 0.0016 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.01 | 0.0579 | 0.0574 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0044 | 0.5075 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0113 | 0.0658 | 0.1601 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0006 | 0.0016 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0024 | 0.0319 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0113 | 0.0658 | 0.1601 |
Plasmodium vivax | hypothetical protein, conserved | 0.0046 | 0.0246 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.025 | 0.0599 |
Echinococcus granulosus | replication factor c subunit 1 | 0.001 | 0.0024 | 0.0044 |
Echinococcus multilocularis | 0.0046 | 0.0246 | 0.024 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0081 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0006 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0301 | 0.0737 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0152 | 0.0902 | 0.0896 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.001 | 0.0024 | 0.0754 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0024 | 0.0319 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0018 | 0.003 |
Brugia malayi | hypothetical protein | 0.001 | 0.0024 | 0.006 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0046 | 0.0246 | 0.0588 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0287 | 0.0703 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0227 | 0.3421 |
Onchocerca volvulus | 0.001 | 0.0024 | 0.0341 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0024 | 0.0319 |
Onchocerca volvulus | 0.0046 | 0.0246 | 0.3451 | |
Brugia malayi | Muscleblind-like protein | 0.0152 | 0.0902 | 0.221 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.001 | 0.0024 | 0.0988 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0074 | 0.018 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Log Ki (binding) | = 2.54 | pKi value expresses binding affinity against thermolysin pKi = -logKi (where Ki is in mol/L) | ChEMBL. | 11931613 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.