Detailed information for compound 57674

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 313.823 | Formula: C15H24ClN3O2
  • H donors: 1 H acceptors: 1 LogP: 2.07 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(CCN(C(=O)c1cc(Cl)c(cc1OC)N)C)CC
  • InChi: 1S/C15H24ClN3O2/c1-5-19(6-2)8-7-18(3)15(20)11-9-12(16)13(17)10-14(11)21-4/h9-10H,5-8,17H2,1-4H3
  • InChiKey: JEUCSMQOUIJAHU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Dopamine D2 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis g protein coupled receptor Dopamine D2 receptor   444 aa 465 aa 21.5 %
Echinococcus granulosus biogenic amine 5HT receptor Dopamine D2 receptor   444 aa 429 aa 31.7 %
Schistosoma japonicum Octopamine receptor, putative Dopamine D2 receptor   444 aa 456 aa 29.4 %
Onchocerca volvulus Glycoprotein hormone beta 5 homolog Dopamine D2 receptor   444 aa 476 aa 24.2 %
Schistosoma mansoni biogenic amine receptor Dopamine D2 receptor   444 aa 452 aa 30.1 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Dopamine D2 receptor   444 aa 432 aa 30.8 %
Loa Loa (eye worm) hypothetical protein Dopamine D2 receptor   444 aa 433 aa 21.2 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Dopamine D2 receptor   444 aa 440 aa 30.0 %
Onchocerca volvulus RB1-inducible coiled-coil protein 1 homolog Dopamine D2 receptor   444 aa 474 aa 23.4 %
Echinococcus multilocularis serotonin receptor Dopamine D2 receptor   444 aa 428 aa 31.3 %
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor Dopamine D2 receptor   444 aa 487 aa 23.8 %
Schistosoma mansoni amine GPCR Dopamine D2 receptor   444 aa 424 aa 32.1 %
Schistosoma mansoni biogenic amine (dopamine) receptor Dopamine D2 receptor   444 aa 494 aa 26.3 %
Echinococcus granulosus g protein coupled receptor Dopamine D2 receptor   444 aa 457 aa 21.0 %
Onchocerca volvulus Dopamine D2 receptor   444 aa 418 aa 23.0 %
Schistosoma japonicum ko:K04207 neuropeptide Y receptor Y5, putative Dopamine D2 receptor   444 aa 386 aa 19.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0014 0.0014
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0206 0.0397 0.0395
Leishmania major beta tubulin 0.0353 0.07 0.07
Echinococcus multilocularis cysteine protease 0.0034 0.0043 0.0043
Loa Loa (eye worm) ctsf protein 0.0034 0.0043 0.0042
Echinococcus multilocularis calmodulin 0.0026 0.0027 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0015 0.0032
Loa Loa (eye worm) neuropeptide F receptor 0.0374 0.0743 0.0741
Trichomonas vaginalis tubulin, putative 0.0112 0.0203 0.0428
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0012 0.0012
Plasmodium falciparum tubulin epsilon chain, putative 0.0197 0.0379 0.0379
Brugia malayi conserved hypotetical protein 0.0019 0.0014 0.0014
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0009 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0058 0.0058
Onchocerca volvulus 0.0029 0.0032 0.003
Onchocerca volvulus 0.0374 0.0743 0.0741
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0016 0.0005 0.0005
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0002 0.0002
Echinococcus granulosus tubulin subunit beta 0.0353 0.07 0.07
Echinococcus multilocularis tar DNA binding protein 0.0125 0.023 0.023
Leishmania major calmodulin, putative 0.0026 0.0027 0.0027
Schistosoma mansoni nAChR subunit 0.0206 0.0397 0.0397
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0057 0.0121
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0012 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0014
Onchocerca volvulus 0.0089 0.0157 0.0156
Brugia malayi jmjC domain containing protein 0.0294 0.0579 0.0579
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.061 0.123 0.1228
Loa Loa (eye worm) hypothetical protein 0.024 0.0467 0.0466
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0029 0.0032 0.003
Echinococcus granulosus tubulin alpha 3 chain 0.0281 0.0552 0.0552
Trypanosoma brucei alpha tubulin, putative 0.0112 0.0203 0.0203
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.0168 0.0168
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0339 0.0715
Loa Loa (eye worm) hypothetical protein 0.0109 0.0199 0.0197
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0304 0.0599 0.0599
Trichomonas vaginalis maltase-glucoamylase, putative 0.0041 0.0057 0.0121
Echinococcus granulosus phd:f box containing protein 0.0029 0.0033 0.0033
Trichomonas vaginalis tubulin gamma chain, putative 0.0197 0.0379 0.0799
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Echinococcus multilocularis peroxidasin 0.0084 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0107 0.0107
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0147 0.0145
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Plasmodium vivax delta tubulin, putative 0.0086 0.015 0.015
Brugia malayi putative neuropeptide receptor 0.0374 0.0743 0.0743
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0086 0.015 0.015
Leishmania major beta tubulin 0.0353 0.07 0.07
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0012 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0117 0.0213 0.0212
Echinococcus granulosus CalModulin family member cmd 1 0.0026 0.0027 0.0027
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0374 0.0743 0.0743
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0029 0.0032 0.0032
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.013 0.0242 0.0242
Schistosoma mansoni inositol monophosphatase 0.0037 0.0049 0.0049
Echinococcus multilocularis tubulin alpha 3 chain 0.0281 0.0552 0.0552
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0058 0.0058
Echinococcus multilocularis jumonji domain containing protein 0.0125 0.0231 0.0231
Echinococcus multilocularis dna polymerase eta 0.002 0.0014 0.0014
Leishmania major beta tubulin 0.0353 0.07 0.07
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0002 0.0004
Echinococcus granulosus cathepsin L 0.0018 0.001 0.001
Brugia malayi hypothetical protein 0.0374 0.0743 0.0743
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0012 0.0012
Onchocerca volvulus 0.0374 0.0743 0.0741
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0374 0.0743 0.0743
Echinococcus granulosus neuropeptide Y receptor 0.0374 0.0743 0.0743
Schistosoma mansoni hypothetical protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Schistosoma mansoni biogenic amine (5HT) receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0002 0.0001
Echinococcus granulosus sodium and chloride dependent glycine 0.0029 0.0032 0.0032
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.0552 0.1163
Echinococcus granulosus smad 0.0026 0.0027 0.0027
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0013 0.0013
Echinococcus multilocularis conserved hypothetical protein 0.1511 0.3084 0.3084
Echinococcus granulosus Tubulin beta 2C chain 0.0353 0.07 0.07
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.0199 0.0419
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0058 0.0058
Plasmodium falciparum heterochromatin protein 1 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0031
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.008 0.0139 0.0139
Schistosoma mansoni microtubule-associated protein tau 0.0692 0.1398 0.1398
Onchocerca volvulus 0.0374 0.0743 0.0741
Echinococcus multilocularis tubulin gamma 1 chain 0.0197 0.0379 0.0379
Schistosoma mansoni survival motor neuron protein 0.0051 0.0079 0.0079
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.4872 1 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0005 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0012 0.0012
Schistosoma mansoni chromobox protein 0.0014 0.0002 0.0002
Echinococcus multilocularis tubulin epsilon chain 0.0197 0.0379 0.0379
Onchocerca volvulus Peroxidasin homolog 0.0084 0.0147 0.0145
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0032 0.0032
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0027 0.0027
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0374 0.0743 0.0743
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0016 0.0005 0.0005
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Brugia malayi hypothetical protein 0.0019 0.0014 0.0014
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0147 0.0145
Brugia malayi CHE-14 protein 0.0056 0.0089 0.0089
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0014 0.0012
Brugia malayi Cell division protein ftsZ 0.0086 0.015 0.015
Brugia malayi PXA domain containing protein 0.0019 0.0012 0.0012
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0058 0.0058
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0012 0.0012
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.008 0.0139 0.0139
Leishmania major cathepsin L-like protease 0.0034 0.0043 0.0043
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0033 0.0031
Leishmania major glycosyl hydrolase-like protein 0.0041 0.0057 0.0057
Onchocerca volvulus Fxna peptidase homolog 0.008 0.0139 0.0137
Trypanosoma cruzi cysteine peptidase, putative 0.013 0.024 0.024
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0014 0.0014
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0085 0.0148 0.0148
Echinococcus granulosus sodium and chloride dependent glycine 0.0029 0.0032 0.0032
Echinococcus multilocularis musashi 0.0033 0.004 0.004
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.0199 0.0419
Echinococcus granulosus importin subunit beta 1 0.0058 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0019
Entamoeba histolytica Ran family GTPase 0.0043 0.0061 0.0851
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0013 0.0028
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0012 0.0012
Schistosoma mansoni biogenic amine receptor 0.0374 0.0743 0.0743
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0175 0.0335 0.0333
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0093 0.0093
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0016 0.0005 0.0005
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0206 0.0397 0.0397
Plasmodium vivax vivapain-3 0.0018 0.001 0.001
Schistosoma mansoni zinc finger protein 0.0019 0.0014 0.0014
Trichomonas vaginalis maltase-glucoamylase, putative 0.011 0.0199 0.0419
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0206 0.0397 0.0397
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0206 0.0397 0.0397
Echinococcus granulosus glycine receptor subunit beta 0.0206 0.0397 0.0397
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0029 0.0032 0.0032
Onchocerca volvulus 0.0374 0.0743 0.0741
Treponema pallidum sodium- and chloride- dependent transporter 0.0168 0.0319 0.3167
Brugia malayi RNA, U transporter 1 0.0165 0.0313 0.0313
Brugia malayi hypothetical protein 0.0084 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Leishmania major cathepsin L-like protease 0.0034 0.0043 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0374 0.0743 0.0743
Trichomonas vaginalis alpha-glucosidase, putative 0.011 0.0199 0.0419
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0016 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0139 0.0293
Schistosoma mansoni amine GPCR 0.0374 0.0743 0.0743
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0112 0.0203 0.0428
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.0168 0.0168
Brugia malayi Tachykinin-like peptides receptor 99D 0.0374 0.0743 0.0743
Loa Loa (eye worm) platelet-activating factor acetylhydrolase 0.0663 0.1337 0.1336
Brugia malayi steroid hormone receptor 0.0041 0.0058 0.0058
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0012 0.0012
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0034 0.0043 0.0042
Mycobacterium leprae conserved hypothetical protein 0.0109 0.0199 0.0193
Mycobacterium tuberculosis Cell division protein FtsZ 0.0086 0.015 0.015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0043 0.0092
Onchocerca volvulus Neuropeptide F receptor homolog 0.0374 0.0743 0.0741
Brugia malayi hypothetical protein 0.0374 0.0743 0.0743
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0016 0.0005 0.0005
Schistosoma mansoni peroxidasin 0.0084 0.0147 0.0147
Echinococcus multilocularis serotonin transporter 0.0168 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.001
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0374 0.0743 0.0743
Brugia malayi Cathepsin L-like precursor 0.0034 0.0043 0.0043
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0043 0.0043
Toxoplasma gondii exonuclease III APE 0.0019 0.0013 0.0013
Schistosoma mansoni amine GPCR 0.0374 0.0743 0.0743
Echinococcus multilocularis Niemann Pick C1 protein 0.0056 0.0089 0.0089
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0058 0.0057
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0109 0.0199 0.0197
Entamoeba histolytica tubulin gamma chain 0.0197 0.0379 0.5402
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0016 0.0005 0.0005
Echinococcus multilocularis neuropeptide receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Echinococcus granulosus Tubulin beta 2C chain 0.0353 0.07 0.07
Leishmania major beta tubulin 0.0353 0.07 0.07
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0121 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.005 0.005
Schistosoma mansoni growth hormone secretagogue receptor 0.0374 0.0743 0.0743
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0079 0.0079
Brugia malayi nicalin 0.008 0.0139 0.0139
Trichomonas vaginalis hypothetical protein 0.0014 0.0002 0.0004
Mycobacterium tuberculosis Conserved protein 0.0109 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Schistosoma mansoni glutaminyl cyclase (M28 family) 0.0505 0.1014 0.1014
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0088 0.0154 0.0154
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0105 0.0105
Echinococcus multilocularis lysine specific demethylase 5A 0.0109 0.0197 0.0197
Echinococcus granulosus dro:myosuppressin receptor 0.0374 0.0743 0.0743
Schistosoma mansoni hypothetical protein 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0041 0.0058 0.0057
Echinococcus multilocularis tubulin subunit TubB 0.0281 0.0552 0.0552
Echinococcus multilocularis rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.024 0.024
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0058 0.0058
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0049 0.0049
Onchocerca volvulus 0.0051 0.0079 0.0077
Brugia malayi latrophilin 2 splice variant baaae 0.0141 0.0263 0.0263
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.003
Echinococcus multilocularis jumonji domain containing 1A 0.0029 0.0033 0.0033
Schistosoma mansoni sodium/chloride dependent transporter 0.0168 0.0319 0.0319
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0374 0.0743 0.0743
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0026 0.0027 0.0027
Echinococcus granulosus nAChR subunit 0.0206 0.0397 0.0397
Echinococcus multilocularis protein patched 0.0056 0.0089 0.0089
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0206 0.0397 0.0397
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0013 0.013
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0016 0.0005 0.0005
Plasmodium vivax vivapain-2 0.0034 0.0043 0.0043
Leishmania major beta tubulin 0.0353 0.07 0.07
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0619 0.1247 0.1245
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0206 0.0397 0.0397
Brugia malayi Uncoordinated protein 44 0.0014 0.0002 0.0002
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.008 0.0139 0.0139
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0374 0.0743 0.0743
Brugia malayi Valyl-tRNA synthetase 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.015 0.0315
Onchocerca volvulus Dual oxidase homolog 0.0084 0.0147 0.0145
Trichomonas vaginalis alpha-glucosidase, putative 0.011 0.0199 0.0419
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0139 0.0293
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.001
Echinococcus multilocularis neuropeptide s receptor 0.1293 0.2635 0.2635
Echinococcus granulosus rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Trypanosoma brucei calmodulin 0.0026 0.0027 0.0027
Onchocerca volvulus 0.0206 0.0397 0.0395
Leishmania major DNA polymerase eta, putative 0.002 0.0014 0.0014
Brugia malayi hypothetical protein 0.0089 0.0157 0.0157
Echinococcus granulosus serotonin receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0061 0.0059
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0034 0.0043 0.0043
Plasmodium vivax tubulin alpha chain, putative 0.0281 0.0552 0.0552
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0374 0.0743 0.0743
Echinococcus multilocularis phd:f box containing protein 0.0029 0.0033 0.0033
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0374 0.0743 0.0741
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0005 0.0003
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0061 0.0061
Schistosoma mansoni histamine h1 receptor 0.0374 0.0743 0.0743
Schistosoma mansoni hypothetical protein 0.0141 0.0263 0.0263
Schistosoma mansoni alpha tubulin 0.0281 0.0552 0.0552
Echinococcus granulosus alpha tubulin 0.0281 0.0552 0.0552
Schistosoma mansoni amine GPCR 0.0374 0.0743 0.0743
Brugia malayi nuclear receptor NHR-67 0.0019 0.0014 0.0014
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0016 0.0005 0.0005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.011 0.0199 0.0419
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0009 0.0009
Onchocerca volvulus 0.0019 0.0014 0.0012
Schistosoma mansoni ap endonuclease 0.0019 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0043 0.0092
Entamoeba histolytica hypothetical protein 0.0108 0.0196 0.2776
Plasmodium vivax tubulin epsilon chain, putative 0.0197 0.0379 0.0379
Loa Loa (eye worm) hypothetical protein 0.0136 0.0254 0.0252
Brugia malayi cytochrome P450 0.0016 0.0005 0.0005
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0051 0.0051
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0016 0.0005 0.0005
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0058 0.0057
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.001 0.001
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Echinococcus granulosus tubulin alpha chain 0.0281 0.0552 0.0552
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Brugia malayi G protein-coupled receptor F59B2.13 0.0374 0.0743 0.0743
Onchocerca volvulus 0.0374 0.0743 0.0741
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0038 0.0038
Brugia malayi chromobox protein homolog 3 0.0047 0.007 0.007
Schistosoma mansoni smad1 5 8 and 0.0026 0.0027 0.0027
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0906 0.1837 0.1836
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0093 0.0093
Schistosoma mansoni tubulin subunit beta 0.0353 0.07 0.07
Leishmania major cathepsin L-like protease 0.0034 0.0043 0.0043
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0014 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0014 0.0014
Schistosoma mansoni phd/f-box containing protein 0.0029 0.0033 0.0033
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0206 0.0397 0.0397
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0029 0.0032 0.0032
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0027 0.0025
Plasmodium vivax JmjC domain containing protein 0.0029 0.0033 0.0033
Brugia malayi Associated with TFs and helicases family protein 0.0014 0.0002 0.0002
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.005 0.005
Echinococcus multilocularis tubulin alpha chain 0.0281 0.0552 0.0552
Echinococcus multilocularis cysteine protease 0.0034 0.0043 0.0043
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0206 0.0397 0.0395
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0013 0.0013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0058 0.0058
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0085 0.0148 0.0148
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0107 0.0107
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0206 0.0397 0.0397
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0164 0.031 0.031
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0374 0.0743 0.0743
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0013 0.0013
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Schistosoma mansoni nAChR subunit 0.0089 0.0157 0.0157
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0321 0.0676
Toxoplasma gondii alpha tubulin TUBA1 0.0281 0.0552 0.0552
Brugia malayi hypothetical protein 0.006 0.0098 0.0098
Echinococcus granulosus neuropeptide s receptor 0.1293 0.2635 0.2635
Giardia lamblia Beta tubulin 0.0353 0.07 1
Mycobacterium tuberculosis Probable lipase LipD 0.0109 0.0199 0.0199
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.0199 0.0419
Echinococcus granulosus glycine receptor subunit alpha 1 0.0206 0.0397 0.0397
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0013 0.0876
Loa Loa (eye worm) hypothetical protein 0.0168 0.0319 0.0317
Brugia malayi MH1 domain containing protein 0.0014 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0619 0.1247 0.1247
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0016 0.0005 0.0005
Leishmania major beta tubulin 0.0353 0.07 0.07
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.0136 0.0254 0.0254
Leishmania major beta tubulin 0.0353 0.07 0.07
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0043 0.0043
Brugia malayi Cathepsin L-like precursor 0.0034 0.0043 0.0043
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0349 0.0347
Schistosoma mansoni hypothetical protein 0.0029 0.0034 0.0034
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0029 0.0033 0.0033
Echinococcus multilocularis chromobox protein 2 0.0014 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0503 0.106
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0016 0.0005 0.0005
Leishmania major hypothetical protein, conserved 0.008 0.0139 0.0139
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0321 0.0676
Brugia malayi Cytochrome P450 family protein 0.0016 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0009 0.0019
Echinococcus granulosus thymidylate synthase 0.4872 1 1
Echinococcus granulosus glutaminyl peptide cyclotransferase 0.0505 0.1014 0.1014
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.001 0.002
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0329 0.0651 0.0651
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0029 0.0032 1
Trichomonas vaginalis Clan MH, family M28, aminopeptidase S-like metallopeptidase 0.008 0.0139 0.0293
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0014 0.0014
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0042 0.0089
Loa Loa (eye worm) hypothetical protein 0.008 0.0139 0.0137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.003
Echinococcus granulosus histone acetyltransferase KAT2B 0.0086 0.0151 0.0151
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0006 0.0006
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0012 0.0012
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.001 0.001
Onchocerca volvulus 0.0374 0.0743 0.0741
Onchocerca volvulus 0.0034 0.0043 0.0042
Schistosoma mansoni jumonji domain containing protein 0.0029 0.0033 0.0033
Echinococcus granulosus tubulin alpha chain 0.0281 0.0552 0.0552
Loa Loa (eye worm) hypothetical protein 0.2129 0.4354 0.4353
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0014 0.0014
Entamoeba histolytica tubulin family protein 0.0353 0.07 1
Schistosoma mansoni jumonji domain containing protein 0.0234 0.0455 0.0455
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Echinococcus granulosus tubulin alpha chain 0.0281 0.0552 0.0552
Entamoeba histolytica tubulin alpha-1 chain 0.0281 0.0552 0.7873
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0032 0.0032
Echinococcus multilocularis peroxisome assembly protein 26 0.0281 0.0552 0.0552
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0029 0.0032 0.0032
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0012 0.0012
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0206 0.0397 0.0397
Schistosoma mansoni adenoreceptor 0.0374 0.0743 0.0743
Leishmania major cathepsin L-like protease 0.0034 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Onchocerca volvulus 0.0117 0.0213 0.0212
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0349 0.0349
Giardia lamblia Gamma tubulin 0.0197 0.0379 0.5413
Schistosoma mansoni hypothetical protein 0.0374 0.0743 0.0743
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0057 0.0121
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0109 0.0199 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0014
Toxoplasma gondii hypothetical protein 0.0029 0.0032 0.0032
Echinococcus granulosus nAChR subunit 0.0117 0.0213 0.0213
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0374 0.0743 0.0743
Loa Loa (eye worm) cysteine protease 0.0034 0.0043 0.0042
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0058 0.0058
Entamoeba histolytica calmodulin, putative 0.0026 0.0027 0.0362
Echinococcus granulosus cathepsin l cysteine peptidase 0.0034 0.0043 0.0043
Trichomonas vaginalis tubulin gamma chain, putative 0.0353 0.07 0.1477
Brugia malayi Phospholipase A2 family protein 0.2129 0.4354 0.4354
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0088 0.0154 0.0154
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0002 0.0001
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0014 0.0174
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0206 0.0397 0.0397
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0349 0.0349
Loa Loa (eye worm) norepinephrine transporter 0.0168 0.0319 0.0317
Echinococcus granulosus ephrin type A receptor 4 A 0.0134 0.025 0.025
Toxoplasma gondii peptidase, M28 family protein 0.008 0.0139 0.0139
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0206 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.003
Schistosoma mansoni neuropeptide receptor 0.0374 0.0743 0.0743
Mycobacterium tuberculosis Hypothetical protein 0.2318 0.4743 0.4743
Brugia malayi nuclear receptor RXR 0.0022 0.0018 0.0018
Plasmodium vivax amine transporter, putative 0.0029 0.0032 0.0032
Onchocerca volvulus 0.0084 0.0147 0.0145
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0117 0.0213 0.0213
Echinococcus multilocularis calmodulin 0.0026 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Schistosoma mansoni cytochrome P450 0.0016 0.0005 0.0005
Entamoeba histolytica tubulin alpha chain, putative 0.0281 0.0552 0.7873
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0109 0.0199 0.0199
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Plasmodium vivax unspecified product 0.0018 0.001 0.001
Echinococcus multilocularis cathepsin L 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0065 0.0107 0.0106
Onchocerca volvulus 0.0034 0.0043 0.0042
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0012 0.0012
Brugia malayi tubulin alpha-2 chain 0.0281 0.0552 0.0552
Brugia malayi jmjC domain containing protein 0.0029 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Echinococcus multilocularis sex peptide receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) alpha-tubulin 0.0281 0.0552 0.055
Treponema pallidum ATP-binding protein (ylxH-1) 0.0502 0.1007 1
Loa Loa (eye worm) hypothetical protein 0.0169 0.0322 0.032
Toxoplasma gondii ABC1 family protein 0.0109 0.0199 0.0199
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0012 0.0012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0374 0.0743 0.0743
Echinococcus multilocularis Tubulin alpha 1 chain 0.0281 0.0552 0.0552
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0012 0.001
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0034 0.0043 0.0043
Onchocerca volvulus 0.0132 0.0245 0.0244
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.011 0.0199 0.2821
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0043 0.0041
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Loa Loa (eye worm) hypothetical protein 0.009 0.0158 0.0157
Trypanosoma cruzi cysteine peptidase, putative 0.013 0.024 0.024
Brugia malayi Serotonin receptor 0.1382 0.2817 0.2817
Leishmania major GTP-binding protein, putative 0.0043 0.0061 0.0061
Trypanosoma brucei beta tubulin 0.0353 0.07 0.07
Mycobacterium leprae cell division protein FtsZ 0.0086 0.015 0.0144
Trichomonas vaginalis ran, putative 0.0043 0.0061 0.0129
Trichomonas vaginalis tubulin alpha chain, putative 0.0197 0.0379 0.0799
Echinococcus granulosus glycine receptor subunit alpha 1 0.0206 0.0397 0.0397
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0374 0.0743 0.0743
Echinococcus multilocularis allatostatin A receptor 0.0374 0.0743 0.0743
Plasmodium falciparum calmodulin 0.0026 0.0027 0.0027
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0061 0.0061
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0374 0.0743 0.0743
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0043 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0374 0.0743 0.0743
Echinococcus multilocularis neuropeptide receptor A26 0.1293 0.2635 0.2635
Brugia malayi intermediate filament protein 0.0033 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Brugia malayi neuropeptide F receptor 0.0374 0.0743 0.0743
Echinococcus granulosus calmodulin 0.0026 0.0027 0.0027
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.007 0.007
Toxoplasma gondii beta-tubulin, putative 0.0353 0.07 0.07
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0014 0.0002 0.0002
Echinococcus granulosus lysosomal alpha glucosidase 0.0494 0.0989 0.0989
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0058 0.0058
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0374 0.0743 0.0743
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0374 0.0743 0.0743
Brugia malayi alpha-tubulin 0.0281 0.0552 0.0552
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0043 0.0092
Giardia lamblia Histone acetyltransferase GCN5 0.0079 0.0136 0.1944
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Schistosoma mansoni phosphatidylserine receptor 0.0029 0.0033 0.0033
Toxoplasma gondii PHD-finger domain-containing protein 0.009 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Echinococcus multilocularis chromobox protein 1 0.0084 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Leishmania major cathepsin L-like protease 0.013 0.024 0.024
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0014 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0041 0.0058 0.0057
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Trichomonas vaginalis tubulin, putative 0.0353 0.07 0.1477
Brugia malayi CHD4 protein 0.0015 0.0005 0.0005
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0147 0.0147
Echinococcus granulosus tm gpcr rhodopsin 0.0374 0.0743 0.0743
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0014 0.0014
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Onchocerca volvulus 0.0329 0.0651 0.065
Brugia malayi TAR-binding protein 0.0125 0.023 0.023
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Toxoplasma gondii PHD-finger domain-containing protein 0.009 0.0158 0.0158
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0012 0.0012
Loa Loa (eye worm) leucyl aminopeptidase 0.008 0.0139 0.0137
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.0136 0.0254 0.0254
Trichomonas vaginalis tubulin epsilon chain, putative 0.0353 0.07 0.1477
Echinococcus granulosus calmodulin 0.0026 0.0027 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0015 0.0032
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0147 0.0147
Onchocerca volvulus 0.0033 0.004 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.024 0.024
Schistosoma mansoni smad1 5 8 and 0.0026 0.0027 0.0027
Brugia malayi tubulin alpha chain - mouse 0.0281 0.0552 0.0552
Echinococcus granulosus cathepsin L cysteine proteinase 0.0034 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Brugia malayi hypothetical protein 0.0089 0.0157 0.0157
Echinococcus granulosus histone acetyltransferase KAT2B 0.0285 0.056 0.056
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0016 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0049 0.3283
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0014 0.0002 0.0002
Echinococcus multilocularis serotonin receptor 0.0374 0.0743 0.0743
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0294 0.0579 0.0579
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.024 0.024
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0012 0.0012
Schistosoma mansoni sodium/chloride dependent transporter 0.0029 0.0032 0.0032
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0016 0.0005 0.0005
Brugia malayi hypothetical protein 0.0374 0.0743 0.0743
Entamoeba histolytica hypothetical protein 0.0108 0.0196 0.2776
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0016 0.0005 0.0005
Onchocerca volvulus 0.0034 0.0043 0.0042
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0032 0.0032
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0206 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Onchocerca volvulus 0.0109 0.0199 0.0197
Giardia lamblia PHD finger protein 15 0.009 0.0158 0.2262
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0206 0.0397 0.0397
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0374 0.0743 0.0743
Leishmania major hypothetical protein, conserved 0.0029 0.0033 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Schistosoma mansoni intermediate filament proteins 0.0033 0.004 0.004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0058 0.0057
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0057 0.0121
Loa Loa (eye worm) Smad1 0.0026 0.0027 0.0025
Brugia malayi Cathepsin L-like precursor 0.0023 0.002 0.002
Schistosoma mansoni nuclear receptor 0.0019 0.0014 0.0014
Onchocerca volvulus 0.0041 0.0058 0.0057
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0012 0.0012
Schistosoma mansoni opsin-like receptor 0.0374 0.0743 0.0743
Plasmodium falciparum histone acetyltransferase GCN5 0.0079 0.0136 0.0136
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0002 0.0004
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0014 0.0029
Plasmodium falciparum cysteine proteinase falcipain 3 0.0034 0.0043 0.0043
Trypanosoma brucei alpha tubulin 0.0281 0.0552 0.0552
Echinococcus multilocularis dro:myosuppressin receptor 0.0374 0.0743 0.0743
Echinococcus multilocularis dnaJ subfamily B 0.041 0.0818 0.0818
Echinococcus multilocularis hypothetical protein 0.0281 0.0552 0.0552
Brugia malayi jmjC domain containing protein 0.0029 0.0033 0.0033
Brugia malayi Cation transporter family protein 0.0206 0.0397 0.0397
Loa Loa (eye worm) thymidylate synthase 0.4872 1 1
Entamoeba histolytica hypothetical protein 0.0019 0.0012 0.014
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Echinococcus multilocularis calmodulin 0.0026 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Echinococcus multilocularis Tubulin beta 2C chain 0.0353 0.07 0.07
Schistosoma mansoni tar DNA-binding protein 0.0125 0.023 0.023
Brugia malayi hypothetical protein 0.0022 0.0018 0.0018
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0014 0.0014
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0014 0.0014
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0032 0.0032
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0242 0.0242
Entamoeba histolytica hypothetical protein 0.0117 0.0213 0.3027
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0029 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0097 0.0174 0.0172
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.011 0.0199 0.2821
Schistosoma mansoni nAChR subunit 0.0206 0.0397 0.0397
Echinococcus granulosus tm gpcr rhodopsin 0.0374 0.0743 0.0743
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0374 0.0743 0.0743
Brugia malayi hypothetical protein 0.0022 0.0018 0.0018
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0195 0.0376 0.0792
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0013 0.0013
Trypanosoma brucei glutaminyl cyclase, putative 0.008 0.0139 0.0139
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0374 0.0743 0.0743
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0013 0.0013
Echinococcus granulosus somatostatin receptor 0.0374 0.0743 0.0743
Brugia malayi Tubulin gamma chain 0.0197 0.0379 0.0379
Trypanosoma cruzi calmodulin, putative 0.0026 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0057 0.0121
Toxoplasma gondii thioredoxin reductase 0.0037 0.005 0.005
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0014 0.0014
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0374 0.0743 0.0743
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Schistosoma mansoni nicalin (M28 family) 0.008 0.0139 0.0139
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0041 0.0058 0.0057
Loa Loa (eye worm) tubulin beta-1 chain 0.0353 0.07 0.0699
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0058 0.0058
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.0136 0.0254 0.0254
Leishmania major beta tubulin 0.0353 0.07 0.07
Echinococcus multilocularis tubulin alpha 1C chain 0.0281 0.0552 0.0552
Loa Loa (eye worm) DR-78 0.0019 0.0014 0.0012
Brugia malayi Tubulin alpha chain 0.0086 0.015 0.015
Trypanosoma cruzi calmodulin 0.0026 0.0027 0.0027
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0002 0.0002
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0206 0.0397 0.0397
Toxoplasma gondii aldehyde dehydrogenase 0.013 0.0242 0.0242
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0049 0.0049
Echinococcus multilocularis Tubulin beta 2C chain 0.0353 0.07 0.07
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0374 0.0743 0.0743
Toxoplasma gondii calmodulin, putative 0.0026 0.0027 0.0027
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0058 0.0058
Schistosoma mansoni apoptosis regulator bax 0.0088 0.0154 0.0154
Schistosoma mansoni cpg binding protein 0.003 0.0036 0.0036
Echinococcus multilocularis lysosomal alpha glucosidase 0.0494 0.0989 0.0989
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0012 0.0012
Brugia malayi Tubulin beta chain 0.0112 0.0203 0.0203
Echinococcus granulosus biogenic amine 5HT receptor 0.0374 0.0743 0.0743
Schistosoma mansoni DNA polymerase eta 0.002 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.006 0.0098 0.0096
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0321 0.0676
Brugia malayi hypothetical protein 0.0374 0.0743 0.0743
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0503 0.106
Loa Loa (eye worm) hypothetical protein 0.0088 0.0154 0.0152
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.001 0.0111
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.4872 1 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0029 0.0032 0.0032
Echinococcus granulosus Chromo domain 0.0014 0.0002 0.0002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0032 0.0032
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.001 0.001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0141 0.0263 0.0261
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0004
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0304 0.0599 0.0599
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0503 0.106
Brugia malayi Pre-SET motif family protein 0.0064 0.0105 0.0105
Loa Loa (eye worm) ACC-1 protein 0.0206 0.0397 0.0395
Mycobacterium tuberculosis Probable lipoprotein aminopeptidase LpqL 0.008 0.0139 0.0139
Trypanosoma brucei C-8 sterol isomerase, putative 0.0409 0.0816 0.0816
Schistosoma mansoni nuclear receptor 0.0019 0.0014 0.0014
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0057 0.0796
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0089 0.0157 0.0157
Toxoplasma gondii beta-1 tubulin, putative 0.0353 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0058 0.0093 0.0091
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Echinococcus granulosus glycine receptor subunit beta 0.0206 0.0397 0.0397
Brugia malayi isocitrate dehydrogenase 0.0034 0.0043 0.0043
Trichomonas vaginalis alpha-glucosidase, putative 0.011 0.0199 0.0419
Loa Loa (eye worm) hypothetical protein 0.0056 0.0089 0.0087
Loa Loa (eye worm) RNA binding protein 0.0125 0.023 0.0228
Onchocerca volvulus Peroxidasin homolog 0.0084 0.0147 0.0145
Echinococcus granulosus Tubulin alpha 1 chain 0.0281 0.0552 0.0552
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Loa Loa (eye worm) melatonin receptor type 1A 0.0374 0.0743 0.0741
Echinococcus granulosus Ankyrin 0.0014 0.0003 0.0003
Echinococcus granulosus microtubule associated protein 2 0.0692 0.1398 0.1398
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.0552 0.1163
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0064 0.0105 0.0103
Onchocerca volvulus 0.0374 0.0743 0.0741
Onchocerca volvulus 0.0089 0.0157 0.0156
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0014 0.0002 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0125 0.023 0.023
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0058 0.0058
Brugia malayi Calcitonin receptor-like protein seb-1 0.0206 0.0397 0.0397
Loa Loa (eye worm) beta-lactamase 0.0109 0.0199 0.0197
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Brugia malayi AKH receptor 0.0374 0.0743 0.0743
Schistosoma mansoni neurotransmitter gated ion channel 0.0089 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Trypanosoma brucei calmodulin 0.0026 0.0027 0.0027
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0005 0.0004
Echinococcus multilocularis G-protein coupled receptor, putative 0.0374 0.0743 0.0743
Echinococcus granulosus expressed protein 0.0361 0.0716 0.0716
Echinococcus multilocularis tubulin alpha chain 0.0281 0.0552 0.0552
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Echinococcus multilocularis lysosomal alpha glucosidase 0.0494 0.0989 0.0989
Brugia malayi nuclear receptor RXR 0.0019 0.0014 0.0014
Echinococcus multilocularis tubulin alpha 0.0197 0.0379 0.0379
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.011 0.0199 0.0419
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0206 0.0397 0.0397
Echinococcus granulosus g protein coupled receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) acetylcholine receptor protein 0.0089 0.0157 0.0156
Brugia malayi calmodulin 0.0026 0.0027 0.0027
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0206 0.0397 0.0397
Echinococcus multilocularis dna polymerase kappa 0.002 0.0014 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.024 0.024
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0058 0.0058
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.002 0.0043
Schistosoma mansoni biogenic amine receptor 0.0374 0.0743 0.0743
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0014
Brugia malayi Tubulin beta chain 0.0086 0.015 0.015
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.0136 0.0254 0.0254
Brugia malayi hypothetical protein 0.0089 0.0157 0.0157
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0061 0.0061
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.0199 0.0199
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0016 0.0005 0.0005
Toxoplasma gondii cathepsin CPL 0.0034 0.0043 0.0043
Plasmodium falciparum alpha tubulin 1 0.0281 0.0552 0.0552
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.2318 0.4743 1
Echinococcus granulosus neuropeptide receptor 0.0374 0.0743 0.0743
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0043 0.0598
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Schistosoma mansoni amine GPCR 0.0374 0.0743 0.0743
Loa Loa (eye worm) tubulin gamma chain 0.0197 0.0379 0.0377
Loa Loa (eye worm) hypothetical protein 0.0281 0.0552 0.055
Brugia malayi jmjC domain containing protein 0.011 0.0201 0.0201
Onchocerca volvulus 0.0329 0.0651 0.065
Brugia malayi sulfakinin receptor protein 0.0374 0.0743 0.0743
Loa Loa (eye worm) tubulin alpha 2 0.0084 0.0146 0.0144
Entamoeba histolytica hypothetical protein 0.0108 0.0196 0.2776
Loa Loa (eye worm) glutathione reductase 0.0037 0.005 0.0048
Leishmania major gamma-tubulin 0.0197 0.0379 0.0379
Schistosoma mansoni coup transcription factor 0.0041 0.0058 0.0058
Schistosoma mansoni tubulin subunit beta 0.0086 0.015 0.015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0374 0.0743 0.0743
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.0136 0.0254 0.0254
Loa Loa (eye worm) tubulin beta-4 chain 0.0353 0.07 0.0699
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0013 0.0013
Echinococcus granulosus tumor protein p63 0.0665 0.1342 0.1342
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0109 0.0199 0.0199
Plasmodium falciparum tubulin gamma chain 0.0197 0.0379 0.0379
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0014 0.0014
Plasmodium vivax tubulin gamma chain, putative 0.0197 0.0379 0.0379
Loa Loa (eye worm) beta-tubulin 0.0353 0.07 0.0699
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.0043 0.0092
Leishmania major beta tubulin 0.0353 0.07 0.07
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.024 0.024
Echinococcus multilocularis neuropeptides capa receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Leishmania major alpha glucosidase II subunit, putative 0.011 0.0199 0.0199
Brugia malayi MH2 domain containing protein 0.0026 0.0027 0.0027
Onchocerca volvulus 0.0034 0.0043 0.0042
Echinococcus granulosus beta LACTamase domain containing family member 0.0109 0.0199 0.0199
Echinococcus multilocularis calmodulin 0.0026 0.0027 0.0027
Onchocerca volvulus 0.008 0.0139 0.0137
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0147 0.0145
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0012
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0206 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Echinococcus granulosus calmodulin 0.0026 0.0027 0.0027
Schistosoma mansoni netrin receptor unc5 0.0014 0.0002 0.0002
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0043 0.0043
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0012 0.001
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0168 0.0319 0.0319
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0016 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Onchocerca volvulus 0.0374 0.0743 0.0741
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0049 0.0049
Loa Loa (eye worm) tubulin alpha-2 chain 0.0281 0.0552 0.055
Echinococcus multilocularis fmrfamide receptor 0.0374 0.0743 0.0743
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0014 0.0014
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.001 0.001
Loa Loa (eye worm) tubulin alpha 2 0.0195 0.0376 0.0374
Echinococcus granulosus Tubulin beta 2C chain 0.0353 0.07 0.07
Onchocerca volvulus Calmodulin homolog 0.0026 0.0027 0.0025
Echinococcus granulosus dnaJ subfamily B 0.041 0.0818 0.0818
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Schistosoma mansoni patched 1 0.0056 0.0089 0.0089
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0005
Brugia malayi MH2 domain containing protein 0.0026 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0089 0.0187
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Schistosoma mansoni biogenic amine receptor 0.0374 0.0743 0.0743
Trypanosoma cruzi calmodulin, putative 0.0026 0.0027 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0015 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Schistosoma mansoni hypothetical protein 0.0088 0.0154 0.0154
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0107 0.0107
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0206 0.0397 0.0397
Mycobacterium ulcerans beta-lactamase 0.0109 0.0199 0.0199
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0003 0.0003
Loa Loa (eye worm) TAR-binding protein 0.0125 0.023 0.0228
Echinococcus granulosus G protein coupled receptor 139 0.0374 0.0743 0.0743
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0374 0.0743 0.0743
Echinococcus multilocularis rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0206 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0004
Echinococcus multilocularis tubulin beta 1 chain 0.0353 0.07 0.07
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0049 0.0104
Trichomonas vaginalis set domain proteins, putative 0.0502 0.1007 0.2123
Trypanosoma brucei phospholipase A1, putative 0.0663 0.1337 0.1337
Loa Loa (eye worm) hypothetical protein 0.0117 0.0213 0.0212
Brugia malayi MH2 domain containing protein 0.0379 0.0754 0.0754
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0027 0.0027
Leishmania major cathepsin L-like protease 0.013 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Mycobacterium tuberculosis Conserved protein 0.0109 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Brugia malayi PHD-finger family protein 0.009 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.008 0.0139 0.0137
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0013 0.0028
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0012 0.0012
Echinococcus multilocularis tubulin alpha chain 0.0281 0.0552 0.0552
Onchocerca volvulus 0.0026 0.0027 0.0025
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0206 0.0397 0.0397
Loa Loa (eye worm) TYRA-2 protein 0.0374 0.0743 0.0741
Onchocerca volvulus Fxna peptidase homolog 0.008 0.0139 0.0137
Schistosoma mansoni hypothetical protein 0.0065 0.0107 0.0107
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0058 0.0058
Onchocerca volvulus 0.0374 0.0743 0.0741
Leishmania major delta tubulin, putative 0.0086 0.015 0.015
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0014 0.0014
Schistosoma mansoni peroxidasin 0.0084 0.0147 0.0147
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0374 0.0743 0.0741
Trypanosoma cruzi beta tubulin, putative 0.0353 0.07 0.07
Brugia malayi Protein kinase domain containing protein 0.0014 0.0002 0.0002
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0002 0.0002
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0206 0.0397 0.0397
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.005 0.0048
Onchocerca volvulus Cell death protein 3 homolog 0.006 0.0098 0.0096
Onchocerca volvulus 0.0078 0.0133 0.0131
Brugia malayi hypothetical protein 0.0374 0.0743 0.0743
Entamoeba histolytica cysteine protease, putative 0.0034 0.0043 0.0598
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Plasmodium vivax tubulin alpha chain, putative 0.0281 0.0552 0.0552
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0014 0.0029
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0088 0.0154 0.0154
Brugia malayi ephrin receptor 1 precursor 0.0065 0.0106 0.0106
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0321 0.0676
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0013 0.0013
Trypanosoma brucei beta tubulin 0.0353 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0019
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0169 0.0322 0.0679
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0374 0.0743 0.0743
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0206 0.0397 0.0397
Onchocerca volvulus 0.0037 0.005 0.0048
Brugia malayi hypothetical protein 0.0251 0.049 0.049
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0206 0.0397 0.0395
Trichomonas vaginalis tubulin alpha chain, putative 0.0112 0.0203 0.0428
Giardia lamblia Beta tubulin 0.0353 0.07 1
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0018 0.0018
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0374 0.0743 0.0743
Brugia malayi ecdysteroid receptor 0.0041 0.0058 0.0058
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.002 0.002
Brugia malayi Cytochrome P450 family protein 0.0016 0.0005 0.0005
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0109 0.0199 0.0199
Schistosoma mansoni nAChR subunit 0.0206 0.0397 0.0397
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0049 0.0049
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0016 0.0005 0.0005
Onchocerca volvulus 0.0206 0.0397 0.0395
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0032 0.0032
Brugia malayi beta-lactamase 0.0109 0.0199 0.0199
Trichomonas vaginalis importin beta-1, putative 0.0047 0.007 0.0148
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0058 0.0058
Onchocerca volvulus 0.0663 0.1337 0.1336
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0043 0.0043
Echinococcus multilocularis neuropeptide Y receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0033 0.004 0.0039
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0043 0.0042
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0043 0.0043
Echinococcus granulosus tm gpcr rhodopsin 0.0374 0.0743 0.0743
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0043 0.0598
Brugia malayi Importin beta-1 subunit 0.0058 0.0093 0.0093
Brugia malayi Death domain containing protein 0.0014 0.0002 0.0002
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0012 0.0012
Echinococcus granulosus cpg binding protein 0.003 0.0036 0.0036
Schistosoma mansoni cpg binding protein 0.0029 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0015 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0004
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0206 0.0397 0.0397
Echinococcus multilocularis nAChR subunit 0.0206 0.0397 0.0397
Brugia malayi nuclear hormone receptor 0.0019 0.0014 0.0014
Brugia malayi Peroxidasin 0.0084 0.0147 0.0147
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0002 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0058 0.0058
Schistosoma mansoni sodium-dependent amino acid transporter 0.0029 0.0032 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Loa Loa (eye worm) apoptosis regulator protein 0.0088 0.0154 0.0152
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0016 0.0005 0.0005
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0064 0.0105 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0005 0.0005
Brugia malayi ecdysone receptor 0.0019 0.0014 0.0014
Toxoplasma gondii alpha-tubulin I, putative 0.0281 0.0552 0.0552
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3211 0.6582 0.6582
Schistosoma mansoni hypothetical protein 0.0374 0.0743 0.0743
Trypanosoma brucei epsilon tubulin 0.0197 0.0379 0.0379
Echinococcus multilocularis glycine receptor subunit beta 0.0206 0.0397 0.0397
Schistosoma mansoni tubulin subunit beta 0.0353 0.07 0.07
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0002 0.0004
Brugia malayi Cathepsin L-like precursor 0.0034 0.0043 0.0043
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0034 0.0034
Mycobacterium tuberculosis Probable lipase LipE 0.0109 0.0199 0.0199
Onchocerca volvulus 0.0029 0.0033 0.0031
Plasmodium falciparum tubulin beta chain 0.0353 0.07 0.07
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0013 0.0013
Echinococcus multilocularis beta LACTamase domain containing family member 0.0109 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Echinococcus multilocularis rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0061 0.0874
Trypanosoma brucei tubulin gamma chain 0.0197 0.0379 0.0379
Onchocerca volvulus Putative nachr subunit 0.0206 0.0397 0.0395
Brugia malayi larval opioid receptor 0.0374 0.0743 0.0743
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Brugia malayi Melatonin receptor type 1A 0.0374 0.0743 0.0743
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0012 0.0024
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0206 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0016 0.0005 0.0005
Onchocerca volvulus 0.0374 0.0743 0.0741
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0086 0.015 0.0315
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0089 0.0157 0.0156
Loa Loa (eye worm) G-protein coupled receptor 0.0374 0.0743 0.0741
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0242 0.0242
Brugia malayi MH1 domain containing protein 0.0014 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.4872 1 1
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0206 0.0397 0.0397
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0029 0.0032 0.0032
Loa Loa (eye worm) BEN-1 protein 0.0353 0.07 0.0699
Schistosoma mansoni neuropeptide f receptor 76f 0.0374 0.0743 0.0743
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0164 0.031 0.031
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0012 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.001 0.001
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0374 0.0743 0.0743
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0024
Echinococcus granulosus cysteine protease 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0154 0.0291 0.0289
Onchocerca volvulus 0.0084 0.0147 0.0145
Mycobacterium tuberculosis Probable reductase 0.0085 0.0148 0.0148
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0014 0.0014
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1237 0.2519 0.2519
Schistosoma mansoni alpha tubulin 0.0281 0.0552 0.0552
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0206 0.0397 0.0397
Trichomonas vaginalis tubulin gamma chain, putative 0.0197 0.0379 0.0799
Echinococcus granulosus g protein coupled receptor 0.0374 0.0743 0.0743
Echinococcus granulosus geminin 0.1383 0.2819 0.2819
Echinococcus granulosus tubulin alpha 3 chain 0.0281 0.0552 0.0552
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0014 0.0014
Echinococcus granulosus Tubulin alpha 1 chain 0.0281 0.0552 0.0552
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0105 0.0105
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0053 0.0053
Brugia malayi Pre-SET motif family protein 0.0441 0.0882 0.0882
Giardia lamblia Beta tubulin 0.0353 0.07 1
Brugia malayi nuclear hormone receptor 0.0041 0.0058 0.0058
Echinococcus granulosus tubulin gamma 1 chain 0.0197 0.0379 0.0379
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0374 0.0743 0.0743
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Schistosoma mansoni tubulin subunit delta 0.0086 0.015 0.015
Leishmania major zeta tubulin, putative 0.0086 0.015 0.015
Brugia malayi PHD-finger family protein 0.0031 0.0037 0.0037
Trypanosoma brucei unspecified product 0.0014 0.0001 0.0001
Giardia lamblia DINP protein human, muc B family 0.002 0.0014 0.0199
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.003
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0109 0.0199 0.0199
Loa Loa (eye worm) tubulin alpha-3 chain 0.0169 0.0322 0.032
Schistosoma mansoni neuropeptide F-like receptor 0.0374 0.0743 0.0743
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0006 0.0006
Echinococcus multilocularis glutaminyl peptide cyclotransferase 0.0505 0.1014 0.1014
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0043 0.0043
Brugia malayi MH1 domain containing protein 0.0026 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Plasmodium falciparum JmjC domain-containing protein, putative 0.0029 0.0033 0.0033
Brugia malayi Cation transporter family protein 0.0329 0.0651 0.0651
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Schistosoma mansoni opsin-like receptor 0.0374 0.0743 0.0743
Giardia lamblia Alpha-tubulin 0.0281 0.0552 0.7878
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0041 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.0374 0.0743 0.0743
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Leishmania major hypothetical protein, conserved 0.0026 0.0027 0.0027
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0018 0.0018
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.0552 0.1163
Leishmania major cytochrome p450-like protein 0.0016 0.0005 0.0005
Echinococcus multilocularis neuropeptide receptor 0.0374 0.0743 0.0743
Echinococcus granulosus 7tm_1 domain containing protein 0.0374 0.0743 0.0743
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0147 0.0145
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0058 0.0058
Echinococcus granulosus apoptotic protease activating factor 1 0.006 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0043 0.0043
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0374 0.0743 0.0743
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0058 0.0058
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.4872 1 1
Loa Loa (eye worm) hypothetical protein 0.0117 0.0213 0.0212
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0441 0.0882 0.088
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0016 0.0005 0.0005
Onchocerca volvulus 0.0663 0.1337 0.1336
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0136 0.0254 0.0254
Onchocerca volvulus 0.4872 1 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0049 0.0049
Echinococcus granulosus tachykinin peptides receptor 99D 0.0374 0.0743 0.0743
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.001 0.0111
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.001
Schistosoma mansoni alpha-glucosidase 0.0425 0.0848 0.0848
Schistosoma mansoni neuropeptide receptor 0.0374 0.0743 0.0743
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.0136 0.0254 0.0254
Onchocerca volvulus 0.0117 0.0213 0.0212
Mycobacterium ulcerans thymidylate synthase 0.4872 1 1
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0089 0.0157 0.0157
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Schistosoma mansoni jumonji/arid domain-containing protein 0.011 0.0201 0.0201
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0374 0.0743 0.0743
Brugia malayi jmjC domain containing protein 0.0029 0.0033 0.0033
Echinococcus granulosus tubulin alpha 1C chain 0.0281 0.0552 0.0552
Entamoeba histolytica acetyltransferase, GNAT family 0.0079 0.0136 0.1924
Leishmania major cysteine peptidase A (CPA) 0.0034 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0024
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0005 0.0005
Onchocerca volvulus 0.0023 0.002 0.0019
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.001 0.0111
Trypanosoma brucei unspecified product 0.002 0.0014 0.0014
Schistosoma mansoni opsin-like receptor 0.0374 0.0743 0.0743
Echinococcus multilocularis calmodulin 0.0026 0.0027 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0014
Loa Loa (eye worm) acetyltransferase 0.0293 0.0577 0.0575
Echinococcus granulosus intermediate filament protein 0.0033 0.004 0.004
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0014 0.0014
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0016 0.0005 0.0005
Echinococcus granulosus cytochrome P450 2K1 0.0016 0.0005 0.0005
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0013 0.0013
Brugia malayi neuropeptide F receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) PHD-finger family protein 0.009 0.0158 0.0157
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0043 0.0043
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0109 0.0199 0.0197
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0014 0.0014
Mycobacterium ulcerans lipase LipD 0.0109 0.0199 0.0199
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0012 0.0012
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0016 0.0005 0.0005
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0089 0.0157 0.0156
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0294 0.0579 0.0579
Trichomonas vaginalis tubulin gamma chain, putative 0.0086 0.015 0.0315
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0058 0.0058
Loa Loa (eye worm) inositol-1 0.0037 0.0049 0.0047
Schistosoma mansoni alpha-1 adrenergic receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0015 0.0032
Brugia malayi follicle stimulating hormone receptor 0.0374 0.0743 0.0743
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0014 0.0014
Schistosoma mansoni acetylcholine receptor subunit beta 0.0089 0.0157 0.0157
Echinococcus multilocularis PHD finger protein rhinoceros 0.009 0.0158 0.0158
Echinococcus multilocularis JmjC domain containing protein 4 0.0029 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Mycobacterium tuberculosis Probable dehydrogenase 0.0085 0.0148 0.0148
Echinococcus multilocularis tubulin alpha chain 0.0281 0.0552 0.0552
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0027 0.0027
Onchocerca volvulus Chorion peroxidase homolog 0.0084 0.0147 0.0145
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0018 0.0018
Echinococcus granulosus tubulin delta chain 0.0086 0.015 0.015
Trypanosoma cruzi phospholipase A1, putative 0.0663 0.1337 0.1337
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0049 0.0049
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.011 0.0199 0.0197
Giardia lamblia Delta tubulin 0.0086 0.015 0.2136
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0086 0.0151 0.0151
Brugia malayi beta-lactamase family protein 0.0109 0.0199 0.0199
Echinococcus multilocularis fmrfamide receptor 0.0374 0.0743 0.0743
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0108 0.0196 0.0196
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0043 0.0043
Mycobacterium ulcerans esterase/lipase LipP 0.0109 0.0199 0.0199
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0093 0.0093
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.041 0.0818 0.0818
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Leishmania major phospholipase A1, putative 0.0663 0.1337 0.1337
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.0199 0.0199
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0058 0.0057
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Loa Loa (eye worm) hypothetical protein 0.0329 0.0651 0.065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Onchocerca volvulus Peroxidase homolog 0.0084 0.0147 0.0145
Echinococcus granulosus rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0024
Brugia malayi glutathione reductase 0.0037 0.005 0.005
Schistosoma mansoni tubulin subunit alpha 0.0281 0.0552 0.0552
Brugia malayi hypothetical protein 0.0029 0.0032 0.0032
Echinococcus multilocularis neuropeptide Y receptor 0.0374 0.0743 0.0743
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.4872 1 1
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0225 0.0436 0.0436
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0058 0.0058
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0033 0.0031
Schistosoma mansoni tubulin subunit epsilon 0.0197 0.0379 0.0379
Echinococcus granulosus caspase 2 0.006 0.0098 0.0098
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0027 0.0027
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0117 0.0213 0.0212
Leishmania major hypothetical protein, conserved 0.0109 0.0199 0.0199
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.001 0.001
Onchocerca volvulus 0.0374 0.0743 0.0741
Leishmania major cytochrome p450-like protein 0.0016 0.0005 0.0005
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0056 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0002 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0033 0.0031
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0032 0.0032
Echinococcus multilocularis expressed protein 0.0361 0.0716 0.0716
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0041 0.0057 0.0056
Schistosoma mansoni lamin 0.0033 0.004 0.004
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0014 0.0014
Brugia malayi MH1 domain containing protein 0.0026 0.0027 0.0027
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0374 0.0743 0.0743
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.013 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0058 0.0057
Schistosoma mansoni tubulin subunit alpha 0.0281 0.0552 0.0552
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.007 0.0148
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0058 0.0058
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0349 0.0349
Echinococcus granulosus jumonji domain containing 1A 0.0029 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0329 0.0651 0.065
Echinococcus granulosus chromobox protein 1 0.0084 0.0147 0.0147
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0374 0.0743 0.0743
Treponema pallidum cell division protein FtsZ 0.0086 0.015 0.1485
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0086 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Schistosoma mansoni nAChR subunit 0.0206 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Echinococcus granulosus tubulin alpha 1C chain 0.0281 0.0552 0.0552
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Brugia malayi hypothetical protein 0.0374 0.0743 0.0743
Brugia malayi Inositol-1 0.0037 0.0049 0.0049
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0108 0.0196 0.0196
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0206 0.0397 0.0397
Trypanosoma brucei glucosidase, putative 0.011 0.0199 0.0199
Trichomonas vaginalis Heterochromatin protein, putative 0.0014 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Brugia malayi Peptidase family M28 containing protein 0.0505 0.1014 0.1014
Echinococcus granulosus sterol regulatory element binding protein 0.0056 0.0089 0.0089
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0013 0.0013
Plasmodium falciparum thioredoxin reductase 0.0037 0.005 0.005
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0105 0.0105
Echinococcus multilocularis neutral alpha glucosidase AB 0.011 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0139 0.0293
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0014
Schistosoma mansoni tubulin subunit alpha 0.0281 0.0552 0.0552
Toxoplasma gondii beta tubulin 0.0353 0.07 0.07
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0012 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0043 0.0043
Trypanosoma cruzi cruzipain precursor, putative 0.013 0.024 0.024
Mycobacterium leprae Probable lipase LipE 0.0109 0.0199 0.0193
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0002 0.0002
Trichomonas vaginalis sucrase-isomaltase, putative 0.011 0.0199 0.0419
Trypanosoma cruzi zeta tubulin, putative 0.0086 0.015 0.015
Schistosoma mansoni Fxna peptidase (M28 family) 0.008 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Onchocerca volvulus 0.0034 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Echinococcus multilocularis Tubulin beta 2C chain 0.0353 0.07 0.07
Giardia lamblia Alpha-tubulin 0.0281 0.0552 0.7878
Echinococcus granulosus neuropeptide FF receptor 2 0.0374 0.0743 0.0743
Echinococcus granulosus fmrfamide receptor 0.0374 0.0743 0.0743
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0058 0.0058
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0061 0.0061
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0051 0.0051
Echinococcus multilocularis ephrin type A receptor 4 A 0.0134 0.025 0.025
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0014 0.0014
Echinococcus granulosus chromobox protein 1 0.0084 0.0147 0.0147
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0057 0.0121
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0058 0.0058
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0005 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0125 0.023 0.023
Echinococcus granulosus tar DNA binding protein 0.0125 0.023 0.023
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0353 0.07 0.07
Schistosoma mansoni hypothetical protein 0.0051 0.0079 0.0079
Echinococcus granulosus Chromobox protein 3 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0049 0.0049
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.001 0.001
Plasmodium falciparum glutathione reductase 0.0037 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Trichomonas vaginalis esterase, putative 0.0109 0.0199 0.0419
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0016 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0043 0.0092
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0027 0.0027
Plasmodium vivax hypothetical protein, conserved 0.0109 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0002 0.0004
Leishmania major epsilon tubulin, putative 0.0197 0.0379 0.0379
Echinococcus multilocularis g protein coupled receptor 0.0374 0.0743 0.0743
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0058 0.0058
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0027 0.0027
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0029 0.0034 0.0034
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0078 0.0133 0.0133
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0147 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.015 0.0315
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0089 0.0157 0.0157
Trypanosoma brucei alpha tubulin 0.0281 0.0552 0.0552
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0374 0.0743 0.0743
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0029 0.0032 0.003
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0058 0.0058
Trypanosoma cruzi tubulin delta chain 0.0086 0.015 0.015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0008 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0015 0.0032
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0012 0.0012
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0117 0.0213 0.0213
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0206 0.0397 0.0397
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0014
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0109 0.0199 0.0199
Schistosoma mansoni glutaminyl-peptide cyclotransferase-related 0.008 0.0139 0.0139
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0049 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0058 0.0058
Loa Loa (eye worm) LGC-31 protein 0.0206 0.0397 0.0395
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0281 0.0552 0.1163
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0117 0.0213 0.0212
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0005 0.0005
Trypanosoma cruzi glutaminyl cyclase, putative 0.008 0.0139 0.0139
Loa Loa (eye worm) G-protein coupled receptor 0.0374 0.0743 0.0741
Loa Loa (eye worm) hypothetical protein 0.0041 0.0058 0.0057
Brugia malayi M-phase phosphoprotein, mpp8 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0168 0.0319 0.0317
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0206 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Echinococcus multilocularis serotonin receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0043 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0199 0.0199
Echinococcus granulosus Tubulin beta 2C chain 0.0353 0.07 0.07
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0206 0.0397 0.0397
Echinococcus multilocularis tumor protein p63 0.0665 0.1342 0.1342
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.4872 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0024
Brugia malayi SET domain containing protein 0.0017 0.0008 0.0008
Trypanosoma cruzi epsilon tubulin, putative 0.0197 0.0379 0.0379
Schistosoma mansoni chromobox protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0047 0.007 0.0069
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0014 0.0014
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Brugia malayi Angiotensin-converting enzyme family protein 0.061 0.123 0.123
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0121 0.0121
Leishmania major beta tubulin 0.0353 0.07 0.07
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0001 0.0001
Brugia malayi excitatory GABA receptor EXP-1A 0.0206 0.0397 0.0397
Schistosoma mansoni smad 0.0026 0.0027 0.0027
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0374 0.0743 0.0743
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0086 0.0151 0.0318
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0206 0.0397 0.0395
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0206 0.0397 0.0397
Onchocerca volvulus 0.0175 0.0335 0.0333
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0339 0.0715
Echinococcus granulosus Niemann Pick C1 protein 0.0056 0.0089 0.0089
Trypanosoma cruzi major cysteine proteinase, putative 0.0102 0.0183 0.0183
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0206 0.0397 0.0397
Echinococcus granulosus rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Schistosoma mansoni neuropeptide receptor 0.0374 0.0743 0.0743
Trypanosoma brucei epsilon tubulin 0.0197 0.0379 0.0379
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0034 0.0034
Brugia malayi Cation transporter family protein 0.0206 0.0397 0.0397
Leishmania major beta tubulin 0.0353 0.07 0.07
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.0199 0.0199
Echinococcus multilocularis sodium and chloride dependent glycine 0.0029 0.0032 0.0032
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0032 0.0032
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0293 0.0577 0.0577
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0012 0.0012
Echinococcus granulosus biogenic amine 5HT receptor 0.0374 0.0743 0.0743
Schistosoma mansoni hypothetical protein 0.1383 0.2819 0.2819
Trypanosoma brucei trypanothione reductase 0.0037 0.005 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.0199 0.0199
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0033 0.0033
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0117 0.0213 0.0213
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0005 0.0005
Schistosoma mansoni alpha glucosidase 0.011 0.0199 0.0199
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0043 0.0092
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0014 0.0012
Brugia malayi Blistered cuticle protein 3 0.0084 0.0147 0.0147
Trypanosoma brucei beta tubulin 0.0353 0.07 0.07
Echinococcus granulosus lamin 0.0033 0.004 0.004
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0058 0.0058
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0078 0.0164
Leishmania major cathepsin L-like protease 0.0034 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0043 0.0043
Trypanosoma cruzi alpha tubulin, putative 0.0281 0.0552 0.0552
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0014
Loa Loa (eye worm) tubulin alpha 2 0.0195 0.0376 0.0374
Loa Loa (eye worm) jmjC domain-containing protein 0.0186 0.0355 0.0354
Echinococcus granulosus tubulin beta 1 chain 0.0353 0.07 0.07
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0027 0.0027
Schistosoma mansoni neuropeptide F-like receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) tubulin alpha chain 0.0281 0.0552 0.055
Echinococcus granulosus g-protein coupled receptor 0.0374 0.0743 0.0743
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0004
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0293 0.0577 0.0577
Echinococcus granulosus Protein patched homolog 1 0.0056 0.0089 0.0089
Mycobacterium tuberculosis Conserved protein 0.0109 0.0199 0.0199
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0329 0.0651 0.0651
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0014 0.0014
Echinococcus granulosus PHD finger protein rhinoceros 0.009 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0067 0.0112 0.011
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0195 0.0376 0.0374
Loa Loa (eye worm) alpha-tubulin 0.0281 0.0552 0.055
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0107 0.0107
Onchocerca volvulus 0.0014 0.0002 0.0000000071242
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.002 0.0043
Echinococcus multilocularis microtubule associated protein 2 0.0692 0.1398 0.1398
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0374 0.0743 0.0743
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0058 0.0057
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.4872 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0043 0.0092
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0058 0.0057
Echinococcus granulosus beta tubulin 0.0353 0.07 0.07
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0257 0.0503 0.0501
Loa Loa (eye worm) serotonin transporter b 0.0168 0.0319 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0004
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0049 0.0104
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0016 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Loa Loa (eye worm) hypothetical protein 0.008 0.0139 0.0137
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0012 0.0012
Echinococcus granulosus lamin dm0 0.0033 0.004 0.004
Leishmania major importin beta-1 subunit, putative 0.0047 0.007 0.007
Plasmodium falciparum tubulin delta chain, putative 0.0086 0.015 0.015
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0105 0.0105
Echinococcus multilocularis tubulin delta chain 0.0086 0.015 0.015
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0503 0.106
Onchocerca volvulus 0.0109 0.0199 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.007 0.0149
Loa Loa (eye worm) hypothetical protein 0.0195 0.0376 0.0374
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0016 0.0005 0.0005
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0088 0.0154 0.0154
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0014 0.0014
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0085 0.0148 0.0143
Onchocerca volvulus 0.0663 0.1337 0.1336
Echinococcus granulosus chromobox protein 2 0.0014 0.0002 0.0002
Brugia malayi hypothetical protein 0.0026 0.0027 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.024 0.024
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0027 0.0027
Trypanosoma brucei beta tubulin 0.0353 0.07 0.07
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0012 0.0012
Brugia malayi jmjC domain containing protein 0.0029 0.0033 0.0033
Trichomonas vaginalis tubulin, putative 0.0086 0.015 0.0315
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0043 0.0092
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0206 0.0397 0.0395
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0016 0.0005 0.0005
Loa Loa (eye worm) neuropeptide F receptor 0.0374 0.0743 0.0741
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Echinococcus granulosus lysine specific demethylase 6a 0.0029 0.0033 0.0033
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0002 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0374 0.0743 0.0743
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0257 0.0503 0.0503
Brugia malayi hypothetical protein 0.0108 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0037 0.005 0.0048
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0043 0.0043
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0014 0.0014
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0048 0.0072 0.0072
Loa Loa (eye worm) BEN-1 protein 0.0353 0.07 0.0699
Brugia malayi Cathepsin L-like precursor 0.0034 0.0043 0.0043
Trichomonas vaginalis tubulin epsilon chain, putative 0.0281 0.0552 0.1163
Echinococcus granulosus serotonin transporter 0.0168 0.0319 0.0319
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0089 0.0157 0.0157
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.0199 0.0419
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0078 0.0164
Echinococcus multilocularis Tubulin alpha 1 chain 0.0281 0.0552 0.0552
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0206 0.0397 0.0397
Echinococcus multilocularis snurportin 1 0.0619 0.1247 0.1247
Loa Loa (eye worm) hypothetical protein 0.0209 0.0404 0.0402
Echinococcus multilocularis sodium and chloride dependent glycine 0.0029 0.0032 0.0032
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0107 0.0107
Schistosoma mansoni neurotransmitter gated ion channel 0.0089 0.0157 0.0157
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0016 0.0005 0.0005
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0027 0.0025
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0031 0.0038 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0058 0.0057
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.0168 0.0163
Trichomonas vaginalis tubulin alpha chain, putative 0.0353 0.07 0.1477
Leishmania major cathepsin L-like protease 0.013 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Echinococcus granulosus neuropeptide receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0058 0.0057
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0043 0.0043
Brugia malayi Heterochromatin protein 1 0.0084 0.0147 0.0147
Echinococcus multilocularis lysine specific demethylase 6a 0.0029 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0108 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Brugia malayi Glycosyl hydrolases family 31 protein 0.011 0.0199 0.0199
Schistosoma mansoni tubulin subunit beta 0.0353 0.07 0.07
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0016 0.0005 0.0005
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0014 0.0014
Mycobacterium ulcerans hypothetical protein 0.0109 0.0199 0.0199
Onchocerca volvulus 0.0019 0.0014 0.0012
Echinococcus granulosus alpha 1A adrenergic receptor 0.0374 0.0743 0.0743
Schistosoma mansoni ephrin receptor 0.0134 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0041 0.0058 0.0057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.001 0.001
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0016 0.0005 0.0005
Echinococcus granulosus tubulin subunit TubB 0.0281 0.0552 0.0552
Trypanosoma cruzi glutaminyl cyclase, putative 0.008 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Echinococcus multilocularis beta tubulin 0.0353 0.07 0.07
Echinococcus granulosus peptide allatostatin:somatostatin 0.0374 0.0743 0.0743
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0013 0.0011
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.0552 0.1163
Loa Loa (eye worm) tubulin beta chain 0.0086 0.015 0.0148
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.001 0.001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0206 0.0397 0.0397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Trypanosoma cruzi zeta tubulin, putative 0.0086 0.015 0.015
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0321 0.0676
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.003
Echinococcus multilocularis glycine receptor subunit beta 0.0206 0.0397 0.0397
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.013 0.0242 0.0242
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Schistosoma mansoni nAChR subunit 0.0206 0.0397 0.0397
Schistosoma mansoni tubulin subunit beta 0.0353 0.07 0.07
Brugia malayi Cathepsin L-like cysteine proteinase 0.0023 0.002 0.002
Loa Loa (eye worm) jmjC domain-containing protein 0.011 0.0201 0.0199
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0014 0.0014
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0005 0.0005
Brugia malayi hypothetical protein 0.0374 0.0743 0.0743
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0014 0.0014
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0099 0.0099
Brugia malayi Tubulin alpha-2 chain 0.0281 0.0552 0.0552
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0374 0.0743 0.0743
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0041 0.0058 0.0057
Schistosoma mansoni cpg binding protein 0.003 0.0036 0.0036
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0242 0.0242
Schistosoma mansoni protein phosphatase 2C 0.0029 0.0033 0.0033
Trichomonas vaginalis bromodomain-containing protein, putative 0.0086 0.0151 0.0318
Echinococcus granulosus rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0015 0.0032
Plasmodium vivax glutathione reductase, putative 0.0037 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0056
Giardia lamblia Epsilon tubulin 0.0086 0.015 0.2136
Brugia malayi Cathepsin L-like precursor 0.0034 0.0043 0.0043
Schistosoma mansoni calmodulin 0.0026 0.0027 0.0027
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0041 0.0041
Echinococcus multilocularis g protein coupled receptor 0.0374 0.0743 0.0743
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0349 0.0349
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.0043 0.0043
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0086 0.015 1
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0043 0.0043
Trypanosoma cruzi cysteine peptidase, putative 0.013 0.024 0.024
Brugia malayi Cathepsin L-like precursor 0.0023 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.003
Echinococcus multilocularis apoptotic protease activating factor 1 0.006 0.0098 0.0098
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.049 0.049
Echinococcus multilocularis tubulin alpha 1C chain 0.0281 0.0552 0.0552
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Loa Loa (eye worm) hypothetical protein 0.0117 0.0213 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0058 0.0058
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.008 0.0139 0.0139
Brugia malayi leucyl aminopeptidase 0.008 0.0139 0.0139
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Schistosoma mansoni amine GPCR 0.0374 0.0743 0.0743
Onchocerca volvulus 0.0029 0.0032 0.003
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0043 0.0043
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0088 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.005 0.005
Echinococcus multilocularis g protein coupled receptor 0.0374 0.0743 0.0743
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0058 0.0058
Brugia malayi putative neuropeptide receptor NPR1 0.0374 0.0743 0.0743
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0014 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0147 0.0309
Brugia malayi Protein cec-1. 0.0014 0.0002 0.0002
Leishmania major C-8 sterol isomerase-like protein 0.0409 0.0816 0.0816
Onchocerca volvulus 0.0374 0.0743 0.0741
Leishmania major beta tubulin 0.0353 0.07 0.07
Onchocerca volvulus Phospholipase A2 homolog 0.0906 0.1837 0.1836
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.001
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.008 0.0139 0.0139
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0136 0.0254 0.0254
Echinococcus granulosus Smad4 0.0026 0.0027 0.0027
Echinococcus multilocularis chromobox protein 1 0.0084 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0089 0.0157 0.0157
Echinococcus multilocularis sterol regulatory element binding protein 0.0056 0.0089 0.0089
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0321 0.0676
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.0043 0.0092
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0374 0.0743 0.0743
Echinococcus granulosus sex peptide receptor 0.0374 0.0743 0.0743
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0016 0.0005 0.0005
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0018 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0012 0.0012
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0014 0.0014
Schistosoma mansoni myosin xvIII 0.0374 0.0743 0.0743
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0014 0.0002 0.0002
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.011 0.0199 0.0199
Echinococcus granulosus allatostatin A receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0107 0.0106
Echinococcus multilocularis orexin receptor type 2 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0109 0.0199 0.0197
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0043 0.0043
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0061 0.0061
Brugia malayi hypothetical protein 0.0017 0.0008 0.0008
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0206 0.0397 0.0397
Toxoplasma gondii hypothetical protein 0.008 0.0139 0.0139
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.0043 0.0043
Echinococcus multilocularis geminin 0.1383 0.2819 0.2819
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.009 0.0158 0.0158
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0037 0.0037
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.0043 0.0043
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0117 0.0213 0.0213
Loa Loa (eye worm) cytochrome P450 0.0016 0.0005 0.0004
Entamoeba histolytica hypothetical protein 0.0108 0.0196 0.2776
Echinococcus granulosus peregrin 0.0097 0.0173 0.0173
Schistosoma mansoni neuropeptide receptor 0.0374 0.0743 0.0743
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.001 0.001
Schistosoma mansoni chromobox protein 0.0084 0.0147 0.0147
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0013 0.0162
Echinococcus multilocularis somatostatin receptor 0.0374 0.0743 0.0743
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0058 0.0058
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0064 0.0105 0.1499
Onchocerca volvulus 0.0084 0.0147 0.0145
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0374 0.0743 0.0743
Plasmodium falciparum transporter, putative 0.0029 0.0032 0.0032
Brugia malayi hypothetical protein 0.0374 0.0743 0.0743
Brugia malayi Glycosyl hydrolases family 31 protein 0.0041 0.0057 0.0057
Onchocerca volvulus 0.0374 0.0743 0.0741
Trypanosoma brucei calmodulin 0.0026 0.0027 0.0027
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0012 0.001
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0242 0.0242
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0349 0.0349
Onchocerca volvulus Glucosylceramidase homolog 0.0169 0.0321 0.0319
Brugia malayi Dopamine receptor 0.0374 0.0743 0.0743
Entamoeba histolytica cysteine proteinase 1, putative 0.0018 0.001 0.0111
Loa Loa (eye worm) hypothetical protein 0.0041 0.0058 0.0057
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0056 0.0089 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Leishmania major DNA polymerase kappa, putative 0.002 0.0014 0.0014
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0002 0.0002
Brugia malayi Serotonin receptor 0.0374 0.0743 0.0743
Echinococcus granulosus snurportin 1 0.0619 0.1247 0.1247
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0024
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0014 0.0002 0.0002
Schistosoma mansoni tubulin subunit gamma 0.0197 0.0379 0.0379
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0057 0.0121
Schistosoma mansoni chromobox protein 0.0084 0.0147 0.0147
Trypanosoma brucei zeta tubulin 0.0086 0.015 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0042 0.0089
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0147 0.0145
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0089 0.0157 0.0157
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0032 0.0032
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0117 0.0213 0.0213
Echinococcus multilocularis lamin 0.0033 0.004 0.004
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0058 0.0058
Echinococcus multilocularis Tubulin alpha 1 chain 0.0281 0.0552 0.0552
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0088 0.0154 0.0154
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0014 0.0014
Trypanosoma brucei unspecified product 0.0014 0.0001 0.0001
Onchocerca volvulus Peroxidase homolog 0.0084 0.0147 0.0145
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0061 0.0061
Schistosoma mansoni smad1 5 8 and 0.0026 0.0027 0.0027
Echinococcus multilocularis GPCR, family 2 0.0065 0.0107 0.0107
Echinococcus granulosus beta tubulin 0.0353 0.07 0.07
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0012 0.0012
Plasmodium vivax SET domain protein, putative 0.0064 0.0105 0.0105
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0089 0.0157 0.0157
Leishmania major calmodulin, putative 0.0026 0.0027 0.0027
Giardia lamblia Calmodulin 0.0026 0.0027 0.0386
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0049 0.0678
Brugia malayi Tubulin beta-1 chain 0.0353 0.07 0.07
Brugia malayi Glycosyl hydrolases family 31 protein 0.0494 0.0989 0.0989
Brugia malayi F/Y-rich N-terminus family protein 0.0041 0.0057 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0199 0.0199
Schistosoma mansoni hypothetical protein 0.0065 0.0107 0.0107
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.0136 0.0254 0.0254
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0016 0.0005 0.0005
Trypanosoma brucei alpha tubulin 0.0281 0.0552 0.0552
Schistosoma mansoni tyrosine kinase 0.0161 0.0304 0.0304
Onchocerca volvulus 0.0097 0.0174 0.0172
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0016 0.0005 0.0005
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0005 0.0004
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Loa Loa (eye worm) ACC-1 protein 0.0206 0.0397 0.0395
Trichomonas vaginalis tubulin alpha chain, putative 0.0112 0.0203 0.0428
Echinococcus granulosus neutral alpha glucosidase AB 0.011 0.0199 0.0199
Brugia malayi nuclear receptor NHR-88 0.0041 0.0058 0.0058
Onchocerca volvulus 0.0112 0.0203 0.0201
Echinococcus multilocularis beta tubulin 0.0353 0.07 0.07
Schistosoma mansoni hypothetical protein 0.006 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0117 0.0213 0.0212
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0168 0.0319 0.0317
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0503 0.106
Trypanosoma brucei hypothetical protein, conserved 0.0109 0.0199 0.0199
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.0199 0.0419
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.024 0.024
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0206 0.0397 0.0397
Trichomonas vaginalis tubulin epsilon chain, putative 0.0353 0.07 0.1477
Loa Loa (eye worm) hypothetical protein 0.0031 0.0037 0.0036
Loa Loa (eye worm) intermediate filament protein 0.0033 0.004 0.0039
Echinococcus multilocularis Chromo domain 0.0014 0.0002 0.0002
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0043 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0058 0.0057
Brugia malayi FXNA 0.008 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0117 0.0213 0.0212
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0078 0.0076
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0058 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.001 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0349 0.0349
Onchocerca volvulus Phospholipase A2 homolog 0.2129 0.4354 0.4353
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0027 0.0027
Mycobacterium ulcerans hypothetical protein 0.008 0.0139 0.0139
Echinococcus granulosus Tubulin alpha 1 chain 0.0281 0.0552 0.0552
Plasmodium vivax hypothetical protein, conserved 0.009 0.0158 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.007 0.0149
Echinococcus granulosus neuropeptides capa receptor 0.0374 0.0743 0.0743
Brugia malayi ORL1-like opioid receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.001
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0014 0.0014
Brugia malayi Cathepsin L-like precursor 0.0034 0.0043 0.0043
Trypanosoma brucei calmodulin 0.0026 0.0027 0.0027
Echinococcus granulosus peroxidasin 0.0084 0.0147 0.0147
Brugia malayi acetyltransferase, GNAT family protein 0.0293 0.0577 0.0577
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0015 0.0032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Brugia malayi Tubulin alpha-2 chain 0.0281 0.0552 0.0552
Brugia malayi beta-tubulin, identical 0.0353 0.07 0.07
Schistosoma mansoni hypothetical protein 0.0065 0.0107 0.0107
Loa Loa (eye worm) tubulin beta-2A chain 0.0353 0.07 0.0699
Loa Loa (eye worm) hypothetical protein 0.0251 0.049 0.0488
Trypanosoma cruzi calmodulin 0.0026 0.0027 0.0027
Trypanosoma brucei glycosyl hydrolase-like protein 0.0041 0.0057 0.0057
Brugia malayi AF-10 protein 0.0029 0.0034 0.0034
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0014 0.0014
Echinococcus granulosus tubulin alpha 0.0197 0.0379 0.0379
Leishmania major beta tubulin 0.0353 0.07 0.07
Trichomonas vaginalis alpha-glucosidase, putative 0.011 0.0199 0.0419
Brugia malayi hypothetical protein 0.2318 0.4743 0.4743
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0043 0.0043
Echinococcus granulosus tubulin epsilon chain 0.0197 0.0379 0.0379
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0043 0.0042
Schistosoma mansoni tubulin subunit beta 0.0353 0.07 0.07
Schistosoma mansoni inositol monophosphatase 0.0037 0.0049 0.0049
Onchocerca volvulus 0.0502 0.1007 0.1006
Brugia malayi Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II family protein 0.0663 0.1337 0.1337
Entamoeba histolytica cysteine proteinase 2 0.0018 0.001 0.0111
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0105 0.0105
Schistosoma mansoni jumonji/arid domain-containing protein 0.011 0.0201 0.0201
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0014 0.0014
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0012 0.0012
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Trichomonas vaginalis tubulin epsilon chain, putative 0.0281 0.0552 0.1163
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Echinococcus granulosus cathepsin l1 0.0023 0.002 0.002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0058 0.0058
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0117 0.0213 0.0213
Onchocerca volvulus 0.006 0.0098 0.0096
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.008 0.0139 0.0139
Echinococcus multilocularis neuropeptide FF receptor 2 0.0374 0.0743 0.0743
Trypanosoma cruzi cysteine protease, putative 0.0018 0.001 0.001
Schistosoma mansoni importin beta-1 0.0058 0.0093 0.0093
Brugia malayi hypothetical protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0206 0.0397 0.0395
Schistosoma mansoni transcription factor LCR-F1 0.0108 0.0196 0.0196
Echinococcus granulosus 7TM GPCR rhodopsin 0.0374 0.0743 0.0743
Mycobacterium tuberculosis Probable hydrolase 0.0109 0.0199 0.0199
Leishmania major beta tubulin 0.0353 0.07 0.07
Leishmania major beta tubulin 0.0353 0.07 0.07
Onchocerca volvulus 0.0029 0.0032 0.003
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0061 0.0061
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0699 0.1412 0.1412
Echinococcus multilocularis protein dispatched 1 0.0056 0.0089 0.0089
Echinococcus multilocularis g-protein coupled receptor 0.0374 0.0743 0.0743
Onchocerca volvulus Cathepsin F homolog 0.0034 0.0043 0.0042
Echinococcus granulosus Tubulin beta 2C chain 0.0353 0.07 0.07
Echinococcus granulosus death domain containing protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0168 0.0319 0.0317
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0014 0.0012
Leishmania major trypanothione reductase 0.0037 0.005 0.005
Onchocerca volvulus 0.0034 0.0043 0.0042
Trichomonas vaginalis tubulin epsilon chain, putative 0.0086 0.015 0.0315
Trypanosoma cruzi tubulin delta chain 0.0086 0.015 0.015
Leishmania major beta tubulin 0.0353 0.07 0.07
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0168 0.0319 0.0319
Schistosoma mansoni alpha tubulin 0.0281 0.0552 0.0552
Echinococcus multilocularis tubulin alpha 3 chain 0.0281 0.0552 0.0552
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0012 0.0012
Toxoplasma gondii hypothetical protein 0.0029 0.0032 0.0032
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0049 0.0049
Brugia malayi G-protein coupled receptor 0.0374 0.0743 0.0743
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0029 0.0032 0.0032
Echinococcus multilocularis Ankyrin 0.0014 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.001 0.002
Echinococcus multilocularis peregrin 0.0097 0.0173 0.0173
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.006 0.0098 0.0096
Loa Loa (eye worm) hypothetical protein 0.0505 0.1014 0.1012
Plasmodium vivax vivapain-2 0.0034 0.0043 0.0043
Echinococcus granulosus tubulin beta 4A class IVa 0.0353 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Brugia malayi Tubulin alpha chain 0.0281 0.0552 0.0552
Schistosoma mansoni tar DNA-binding protein 0.0125 0.023 0.023
Echinococcus granulosus orexin receptor type 2 0.0374 0.0743 0.0743
Entamoeba histolytica hypothetical protein 0.0019 0.0012 0.014
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Brugia malayi Dopamine receptor protein 1 0.0374 0.0743 0.0743
Onchocerca volvulus Fxna peptidase homolog 0.008 0.0139 0.0137
Echinococcus multilocularis tubulin alpha chain 0.0281 0.0552 0.0552
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0058 0.0058
Loa Loa (eye worm) nuclear factor I 0.0014 0.0003 0.0001
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0088 0.0154 0.0154
Trypanosoma cruzi epsilon tubulin, putative 0.0197 0.0379 0.0379
Leishmania major beta tubulin 0.0353 0.07 0.07
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0058 0.0058
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0086 0.015 0.015
Brugia malayi hypothetical protein 0.0019 0.0012 0.0012
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0005 0.0005
Echinococcus multilocularis thymidylate synthase 0.4872 1 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0206 0.0397 0.0397
Onchocerca volvulus Alhambra homolog 0.009 0.0158 0.0157
Plasmodium falciparum phd finger protein, putative 0.009 0.0158 0.0158
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0374 0.0743 0.0741
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0206 0.0397 0.0397
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0002 0.0002
Mycobacterium ulcerans lipoprotein aminopeptidase LpqL 0.008 0.0139 0.0139
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0494 0.0989 0.0988
Brugia malayi PXA domain containing protein 0.0019 0.0012 0.0012
Schistosoma mansoni tubulin subunit alpha 0.0086 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Plasmodium vivax calmodulin, putative 0.0026 0.0027 0.0027
Schistosoma mansoni acetylcholine receptor-related 0.0089 0.0157 0.0157
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0018 0.0018
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.2318 0.4743 0.4743
Loa Loa (eye worm) hypothetical protein 0.0026 0.0027 0.0025
Schistosoma mansoni nAChR subunit 0.0206 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0041 0.0058 0.0057
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.0168 0.0168
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0016 0.0005 0.0005
Schistosoma mansoni ap endonuclease 0.0019 0.0013 0.0013
Loa Loa (eye worm) transcription factor SMAD2 0.0379 0.0754 0.0752
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0019
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.013 0.0242 0.0242
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0085 0.0148 0.0148
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0321 0.0676
Brugia malayi tailless protein 0.0019 0.0014 0.0014
Onchocerca volvulus 0.0374 0.0743 0.0741
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0349 0.0349
Brugia malayi Smad1 0.0026 0.0027 0.0027
Trypanosoma brucei zeta tubulin, putative 0.0086 0.015 0.015
Schistosoma mansoni hypothetical protein 0.0014 0.0002 0.0002
Leishmania major beta tubulin 0.0353 0.07 0.07
Schistosoma mansoni nAChR subunit 0.0206 0.0397 0.0397
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0503 0.106
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0014 0.0012
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0012 0.0012
Leishmania major calmodulin, putative 0.0026 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.009 0.0158 0.0158
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Onchocerca volvulus Glutaminyl cyclase homolog 0.0505 0.1014 0.1012
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0012 0.001
Loa Loa (eye worm) blistered cuticle protein 3 0.0084 0.0147 0.0145
Mycobacterium tuberculosis Probable esterase LipL 0.0109 0.0199 0.0199
Echinococcus granulosus JmjC domain containing protein 4 0.0029 0.0033 0.0033
Echinococcus multilocularis smad 0.0026 0.0027 0.0027
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0089 0.0157 0.0157
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0206 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0026 0.0027 0.0025
Brugia malayi hypothetical protein 0.0019 0.0012 0.0012
Echinococcus granulosus dna polymerase kappa 0.002 0.0014 0.0014
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0086 0.0151 0.0151
Onchocerca volvulus 0.0109 0.0199 0.0197
Mycobacterium tuberculosis Conserved protein 0.008 0.0139 0.0139
Brugia malayi cathepsin L-like precursor 0.0023 0.002 0.002
Echinococcus granulosus neuropeptide Y receptor 0.0374 0.0743 0.0743
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0041 0.0057 0.0057
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0033 0.0031
Schistosoma mansoni ran 0.0043 0.0061 0.0061
Loa Loa (eye worm) MH2 domain-containing protein 0.0379 0.0754 0.0752
Echinococcus multilocularis G protein coupled receptor 139 0.0374 0.0743 0.0743
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.0552 0.1163
Brugia malayi hypothetical protein 0.0374 0.0743 0.0743
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.024 0.024
Echinococcus multilocularis Tubulin beta 2C chain 0.0353 0.07 0.07
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0374 0.0743 0.0741
Loa Loa (eye worm) tubulin alpha chain 0.0281 0.0552 0.055
Brugia malayi nuclear receptor NHR-88 0.0019 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.008 0.0139 0.0137
Brugia malayi hypothetical protein 0.0089 0.0157 0.0157
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0014 0.0014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0018 0.0018
Brugia malayi Cell death protein 3 precursor 0.006 0.0098 0.0098
Onchocerca volvulus 0.0329 0.0651 0.065
Plasmodium vivax heterochromatin protein 1, putative 0.0014 0.0002 0.0002
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0109 0.0199 0.0197
Brugia malayi hypothetical protein 0.0374 0.0743 0.0743
Schistosoma mansoni hypothetical protein 0.0065 0.0107 0.0107
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0032 0.0032
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0058 0.0058
Schistosoma mansoni tubulin subunit beta 0.0353 0.07 0.07
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.0043 0.0043
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0029 0.0032 0.0032
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0029 0.0032 0.0032
Loa Loa (eye worm) TK/EPH protein kinase 0.0171 0.0325 0.0323
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0041 0.0036
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0064 0.0105 0.0221
Echinococcus multilocularis nAChR subunit 0.0117 0.0213 0.0213
Plasmodium falciparum importin beta, putative 0.0058 0.0093 0.0093
Leishmania major glutaminyl cyclase, putative 0.008 0.0139 0.0139
Schistosoma mansoni sodium/chloride dependent transporter 0.0029 0.0032 0.0032
Trypanosoma brucei alpha tubulin 0.0281 0.0552 0.0552
Echinococcus multilocularis tubulin subunit beta 0.0353 0.07 0.07
Leishmania major cytochrome p450-like protein 0.0016 0.0005 0.0005
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.007 0.0069
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0374 0.0743 0.0743
Trypanosoma cruzi phospholipase A1, putative 0.0663 0.1337 0.1337
Loa Loa (eye worm) GABA receptor subunit 0.0117 0.0213 0.0212
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0016 0.0005 0.0005
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.001 0.001
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0012 0.0012
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0374 0.0743 0.0743
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0374 0.0743 0.0741
Echinococcus granulosus glycine receptor subunit alpha 1 0.0206 0.0397 0.0397
Brugia malayi hypothetical protein 0.0089 0.0157 0.0157
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0027 0.0027
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.1383 0.2819 0.2819
Trypanosoma brucei beta tubulin 0.0197 0.0379 0.0379
Schistosoma mansoni cellular tumor antigen P53 0.0097 0.0174 0.0174
Trypanosoma cruzi calmodulin, putative 0.0026 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0084 0.0147 0.0145
Trichomonas vaginalis tubulin alpha chain, putative 0.0112 0.0203 0.0428
Echinococcus multilocularis 0.0016 0.0005 0.0005
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0089 0.0157 0.0157
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0012 0.0012
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0043 0.0092
Schistosoma mansoni alpha-glucosidase 0.0425 0.0848 0.0848
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.007 0.0148
Schistosoma mansoni hypothetical protein 0.0088 0.0154 0.0154
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0027 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0409 0.0816 0.0814
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0064 0.0105 0.0221
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0032 0.0032
Onchocerca volvulus 0.0374 0.0743 0.0741
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0016 0.0005 0.0005
Toxoplasma gondii cytochrome p450 superfamily protein 0.0016 0.0005 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0002 0.0004
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0374 0.0743 0.0743
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0374 0.0743 0.0743
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0105 0.0105
Schistosoma mansoni lamin 0.0033 0.004 0.004
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0058 0.0057
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0197 0.0379 0.0379
Onchocerca volvulus 0.0285 0.0561 0.0559
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0043 0.0092
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.4872 1 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0107 0.0107
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0014 0.0014
Mycobacterium ulcerans cell division protein FtsZ 0.0086 0.015 0.015
Echinococcus multilocularis calmodulin 0.0026 0.0027 0.0027
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0043 0.0092
Schistosoma mansoni neurotransmitter gated ion channel 0.0117 0.0213 0.0213
Echinococcus multilocularis caspase 2 0.006 0.0098 0.0098
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Echinococcus multilocularis Tubulin beta 2C chain 0.0353 0.07 0.07
Brugia malayi G-protein coupled receptor 0.0374 0.0743 0.0743
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0089 0.0157 0.0157
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0034 0.0043 0.0042
Trichomonas vaginalis alpha-glucosidase, putative 0.011 0.0199 0.0419
Onchocerca volvulus 0.0089 0.0157 0.0156
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0001 0.0001
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0016 0.0005 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0374 0.0743 0.0743
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0029 0.0033 0.0033
Brugia malayi RE15519p 0.0374 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0001
Echinococcus granulosus tubulin alpha chain 0.0281 0.0552 0.0552
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0027 0.0027
Schistosoma mansoni caspase-7 (C14 family) 0.006 0.0098 0.0098
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0043 0.0042
Echinococcus granulosus cathepsin l1 0.0034 0.0043 0.0043
Brugia malayi Thioredoxin reductase 0.0037 0.005 0.005
Trypanosoma cruzi cysteine peptidase, putative 0.0034 0.0043 0.0043
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0012 0.0012
Schistosoma mansoni Smad4 0.0026 0.0027 0.0027
Onchocerca volvulus 0.0206 0.0397 0.0395
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0029 0.0033 0.0033
Trichomonas vaginalis tubulin beta chain, putative 0.0112 0.0203 0.0428
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0014 0.0014
Echinococcus granulosus jumonji domain containing protein 0.0125 0.0231 0.0231
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0057 0.0121
Echinococcus granulosus tubulin alpha chain 0.0281 0.0552 0.0552
Plasmodium falciparum alpha tubulin 2 0.0281 0.0552 0.0552
Trichomonas vaginalis tubulin, putative 0.0112 0.0203 0.0428
Echinococcus granulosus neuropeptide receptor A26 0.1293 0.2635 0.2635
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.001
Brugia malayi G protein-coupled receptor 0.0374 0.0743 0.0743
Onchocerca volvulus 0.0374 0.0743 0.0741
Echinococcus multilocularis lamin dm0 0.0033 0.004 0.004
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.024 0.024
Echinococcus granulosus g protein coupled receptor 0.0374 0.0743 0.0743
Entamoeba histolytica hypothetical protein 0.0047 0.007 0.0979
Plasmodium vivax vivapain-1 0.0018 0.001 0.001
Echinococcus multilocularis neuropeptides capa receptor 0.0374 0.0743 0.0743
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0014 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0016 0.0005 0.0005
Echinococcus granulosus neuropeptides capa receptor 0.0374 0.0743 0.0743
Echinococcus granulosus GPCR family 2 0.0065 0.0107 0.0107
Brugia malayi GnHR receptor homolog 0.0374 0.0743 0.0743
Echinococcus multilocularis Chromobox protein 3 0.0014 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.024 0.024
Entamoeba histolytica tubulin family protein 0.0353 0.07 1
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0058 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0012 0.0012
Brugia malayi Bromodomain containing protein 0.0097 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0374 0.0743 0.0741
Plasmodium vivax tubulin beta chain, putative 0.0353 0.07 0.07
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0105 0.0105
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0014 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.002 0.0266
Brugia malayi CXXC zinc finger family protein 0.0029 0.0033 0.0033
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0032 0.0032
Brugia malayi Dopamine receptor protein 2 0.0374 0.0743 0.0743
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0004
Loa Loa (eye worm) fibroinase 0.0034 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.0206 0.0397 0.0395
Brugia malayi Cytochrome P450 family protein 0.0034 0.0043 0.0043
Echinococcus granulosus lysine specific demethylase 5A 0.011 0.0201 0.0201
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0013 0.0013
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0012
Schistosoma mansoni nAChR subunit 0.0089 0.0157 0.0157
Brugia malayi beta-lactamase family protein 0.0109 0.0199 0.0199
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0409 0.0816 0.0816
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0089 0.0157 0.0157
Plasmodium falciparum amino acid transporter, putative 0.0029 0.0032 0.0032
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0409 0.0816 0.0816
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0374 0.0743 0.0741
Loa Loa (eye worm) hypothetical protein 0.0109 0.0199 0.0197
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0034 0.0034
Brugia malayi Cytochrome P450 family protein 0.0016 0.0005 0.0005
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0206 0.0397 0.0397
Echinococcus granulosus calmodulin 0.0026 0.0027 0.0027
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0058 0.0058
Entamoeba histolytica cysteine protease, putative 0.0018 0.001 0.0111
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0089 0.0157 0.0156
Echinococcus granulosus peroxisome assembly protein 26 0.0281 0.0552 0.0552
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.023 0.0228
Leishmania major dihydrofolate reductase-thymidylate synthase 0.4872 1 1
Onchocerca volvulus 0.0374 0.0743 0.0741
Loa Loa (eye worm) tubulin beta chain 0.0353 0.07 0.0699
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0206 0.0397 0.0395
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0374 0.0743 0.0743
Entamoeba histolytica hypothetical protein 0.0019 0.0012 0.014
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.049 0.049
Trichomonas vaginalis tubulin beta chain, putative 0.0353 0.07 0.1477
Trypanosoma brucei tubulin delta chain 0.0086 0.015 0.015
Echinococcus granulosus dna polymerase eta 0.002 0.0014 0.0014
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0147 0.0147
Brugia malayi RNA binding protein 0.0125 0.023 0.023
Schistosoma mansoni ran 0.0043 0.0061 0.0061
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0105 0.0105
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0118 0.0217 0.0217
Echinococcus multilocularis cpg binding protein 0.003 0.0036 0.0036
Onchocerca volvulus 0.0033 0.004 0.0039
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0013 0.0187
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0016 0.0005 0.0005
Brugia malayi hypothetical protein 0.0175 0.0335 0.0335
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.001 0.0111
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0012 0.0012
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.0552 0.1163
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0058 0.0058
Echinococcus granulosus hypothetical protein 0.1885 0.3853 0.3853
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0147 0.0309
Loa Loa (eye worm) hypothetical protein 0.0132 0.0245 0.0244
Leishmania major alpha tubulin 0.0281 0.0552 0.0552
Trypanosoma cruzi tubulin gamma chain 0.0197 0.0379 0.0379
Echinococcus multilocularis Smad4 0.0026 0.0027 0.0027
Trichomonas vaginalis calmodulin, putative 0.0026 0.0027 0.0057
Loa Loa (eye worm) solute carrier family 6 member 4 0.0168 0.0319 0.0317
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0029 0.0033 0.0033
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.023 0.023
Trypanosoma brucei epsilon tubulin 0.0197 0.0379 0.0379
Brugia malayi hypothetical protein 0.0019 0.0014 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0125 0.023 0.023
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0085 0.0148 0.0148
Plasmodium vivax importin-beta 2, putative 0.0058 0.0093 0.0093

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) > 3 mg kg-1 In vivo antagonism activity against dopamine D2 receptor was measured as emesis in dog when administered subcutaneously ChEMBL. 3397992
ED50 (functional) > 3 mg kg-1 In vivo antagonism activity against dopamine D2 receptor was measured as emesis in dog when administered subcutaneously ChEMBL. 3397992
ED50 (functional) > 40 mg kg-1 In vivo antagonistic activity against dopamine D2 receptor was measured as catalepsy in rat when administered subcutaneously ChEMBL. 3397992
ED50 (functional) > 40 mg kg-1 In vivo antagonism activity against D2 receptor was measured as stereotypy in rat when administered subcutaneously ChEMBL. 3397992
ED50 (functional) > 40 mg kg-1 In vivo antagonistic activity against dopamine D2 receptor was measured as catalepsy in rat when administered subcutaneously ChEMBL. 3397992
ED50 (functional) > 40 mg kg-1 In vivo antagonism activity against D2 receptor was measured as stereotypy in rat when administered subcutaneously ChEMBL. 3397992
Emetic episodes (functional) = 8.7 In vivo antagonism of cisplatin-induced emesis in ferret measured as emetic episodes, twice the dose of 3 mg/kg and in 3 ferrets ChEMBL. 3397992
IC50 (binding) > 1000 nM In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]-spiperone binding ChEMBL. 3397992
IC50 (binding) > 1000 nM In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]-spiperone binding ChEMBL. 3397992
Protection (functional) = 0 % In vivo antagonism of cisplatin-induced emesis in ferret measured as percentage protection for twice the dose of 3 mg/kg and in 3 ferrets ChEMBL. 3397992

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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