Detailed information for compound 576756

Basic information

Technical information
  • TDR Targets ID: 576756
  • Name: [(2R)-3-(4-acetamidophenoxy)-2-hydroxy-propyl ]-isopropyl-ammonium
  • MW: 267.344 | Formula: C14H23N2O3+
  • H donors: 3 H acceptors: 2 LogP: 0.82 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@@H](COc1ccc(cc1)NC(=O)C)C[NH2+]C(C)C
  • InChi: 1S/C14H22N2O3/c1-10(2)15-8-13(18)9-19-14-6-4-12(5-7-14)16-11(3)17/h4-7,10,13,15,18H,8-9H2,1-3H3,(H,16,17)/p+1/t13-/m1/s1
  • InChiKey: DURULFYMVIFBIR-CYBMUJFWSA-O  


Substructure search Similarity search

Network

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Synonyms

  • [(2R)-3-(4-acetamidophenoxy)-2-hydroxypropyl]-isopropylammonium
  • [(2R)-3-(4-acetamidophenoxy)-2-hydroxy-propyl]-propan-2-yl-azanium
  • [(2R)-3-(4-acetamidophenoxy)-2-hydroxypropyl]-propan-2-ylazanium
  • Practolol
  • ZINC00000652

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus granulosus serotonin receptor 0.0027 0.0112 0.0078
Echinococcus granulosus GPCR family 2 0.0052 0.0391 0.0358
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Leishmania major importin beta-1 subunit, putative 0.0028 0.0118 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0504 0.5513 0.6104
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0025 0.0088 0.003
Echinococcus granulosus Proteasome subunit alpha type 7 0.0092 0.084 0.0808
Schistosoma mansoni zinc finger protein 0.0238 0.2496 0.445
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0112 0.0078
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0112 0.0078
Echinococcus multilocularis lamin 0.0033 0.0171 0.0137
Leishmania major proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0092 0.084 0.1456
Brugia malayi hypothetical protein 0.0257 0.2716 0.3008
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0141
Schistosoma mansoni biogenic amine receptor 0.0027 0.0112 0.0141
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0092 0.084 0.1398
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Trypanosoma cruzi 20S proteasome subunit 0.0217 0.2258 0.2472
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0341 0.0341
Leishmania major cytochrome p450-like protein 0.0059 0.0475 0.049
Echinococcus multilocularis dna polymerase eta 0.0048 0.0341 0.0308
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Brugia malayi hypothetical protein 0.0024 0.0072 0.008
Onchocerca volvulus 0.0027 0.0112 0.0074
Schistosoma mansoni coup transcription factor 0.0504 0.5513 0.9903
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0092 0.084 0.1398
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0347 0.373 0.3708
Echinococcus granulosus proteasome subunit beta type 6 0.0092 0.084 0.0808
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0244 0.257 0.4583
Echinococcus granulosus muscleblind protein 0.0163 0.1643 0.1614
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0236 0.0363
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0092 0.084 0.1398
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0362 0.0364
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0504 0.5513 0.6104
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0092 0.084 0.1398
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0141
Brugia malayi 20S proteasome alpha5 subunit 0.0092 0.084 0.093
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0362 0.0328
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0112 0.0078
Brugia malayi follicle stimulating hormone receptor 0.0305 0.3257 0.3606
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.3333 0.3691
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0092 0.084 0.1372
Brugia malayi nuclear receptor RXR 0.0238 0.2496 0.2764
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0362 0.0328
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0072 0.0038
Leishmania major proteasome beta 7 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0159 0.0225
Schistosoma mansoni nuclear hormone receptor 0.0238 0.2496 0.445
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0059 0.0475 0.0796
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0092 0.084 0.5
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0092 0.084 0.1456
Onchocerca volvulus 0.0238 0.2496 0.4455
Brugia malayi Pre-SET motif family protein 0.0031 0.0159 0.0176
Plasmodium vivax importin-beta 2, putative 0.0034 0.0191 0.0217
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0092 0.084 0.1372
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0059 0.0475 0.0796
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0059 0.0475 0.0796
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0305 0.3257 0.3606
Brugia malayi G-protein coupled receptor 0.0027 0.0112 0.0125
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0059 0.0475 0.049
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi larval opioid receptor 0.0027 0.0112 0.0125
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0134 0.132 0.1429
Brugia malayi proteasome subunit alpha type 3 0.0092 0.084 0.093
Schistosoma mansoni RAR-like nuclear receptor 0.0504 0.5513 0.9903
Echinococcus granulosus proteasome subunit beta type 7 0.0092 0.084 0.0808
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0092 0.084 0.0895
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0504 0.5513 0.9903
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0504 0.5513 0.6104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0504 0.5513 0.6104
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0504 0.5513 0.6104
Schistosoma mansoni alpha-1 adrenergic receptor 0.0027 0.0112 0.0141
Loa Loa (eye worm) hypothetical protein 0.0163 0.1643 0.182
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.008
Leishmania major proteasome alpha 1 subunit, putative 0.0092 0.084 0.0895
Echinococcus granulosus proteasome prosome macropain 0.0509 0.5566 0.5551
Loa Loa (eye worm) hypothetical protein 0.0032 0.0164 0.0182
Brugia malayi Serotonin receptor 0.0027 0.0112 0.0125
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0092 0.084 0.0895
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0112 0.0078
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0253 0.0395
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0092 0.084 0.0895
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0236 0.0261
Schistosoma mansoni loxhd1 0.0024 0.0072 0.0068
Onchocerca volvulus 0.0031 0.0159 0.016
Loa Loa (eye worm) hypothetical protein 0.0266 0.2819 0.3122
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0027 0.0112 0.0141
Trichomonas vaginalis esterase, putative 0.0038 0.0236 0.0363
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0092 0.084 0.0895
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0092 0.084 0.1456
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0112 0.0078
Entamoeba histolytica Ran family GTPase 0.0025 0.0088 0.0097
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0294 0.0469
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0059 0.0475 0.0796
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0092 0.084 0.1398
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0163 0.1643 0.182
Echinococcus multilocularis RUN 0.0024 0.0072 0.0038
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0092 0.084 0.1456
Loa Loa (eye worm) nuclear hormone receptor 0.0238 0.2496 0.2764
Loa Loa (eye worm) PDE1B protein 0.0393 0.425 0.4705
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.084 0.1456
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0504 0.5513 0.9903
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0147 0.0125
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0059 0.0475 0.0796
Brugia malayi G-protein coupled receptor 0.0027 0.0112 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0504 0.5513 0.6104
Brugia malayi nuclear receptor NHR-88 0.0238 0.2496 0.2764
Echinococcus multilocularis ecdysone induced protein 78C 0.0504 0.5513 0.5497
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0059 0.0475 0.0796
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0504 0.5513 0.5497
Echinococcus granulosus geminin 0.0205 0.2119 0.2092
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0027 0.0112 0.0141
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Plasmodium falciparum importin beta, putative 0.0034 0.0191 0.0217
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0092 0.084 0.0895
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0491 0.0825
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.003 0.0147 0.0163
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0059 0.0475 0.0796
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0027 0.0112 0.0141
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0112 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0504 0.5513 0.6104
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0112 0.0078
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0092 0.084 0.1398
Loa Loa (eye worm) PAS-3 protein 0.0092 0.084 0.093
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Brugia malayi Melatonin receptor type 1A 0.0027 0.0112 0.0125
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0112 0.0125
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0059 0.0475 0.0796
Onchocerca volvulus 0.0027 0.0112 0.0074
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0112 0.0125
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0141
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0072 0.008
Onchocerca volvulus 0.0038 0.0236 0.0301
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0078
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0238 0.2496 0.445
Echinococcus multilocularis proteasome subunit beta type 7 0.0092 0.084 0.0808
Leishmania major proteasome beta 2 subunit, putative 0.0217 0.2258 0.2472
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0092 0.084 0.1372
Brugia malayi ORL1-like opioid receptor 0.0027 0.0112 0.0125
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0217 0.2258 0.402
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0141
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Giardia lamblia 20S proteasome alpha subunit 3 0.0092 0.084 0.1456
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0504 0.5513 0.6104
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Echinococcus granulosus thyroid hormone receptor alpha 0.0238 0.2496 0.247
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0092 0.084 0.0895
Brugia malayi hypothetical protein 0.0238 0.2496 0.2764
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0025 0.0088 0.0098
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0238 0.2496 0.247
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0236 0.0363
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0112 0.0078
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0067 0.0557 0.0524
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0141
Schistosoma mansoni hypothetical protein 0.0366 0.395 0.7079
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0092 0.084 0.1456
Loa Loa (eye worm) proteasome subunit beta type 3 0.0092 0.084 0.093
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0059 0.0475 0.0796
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0294 0.0469
Echinococcus multilocularis GPCR, family 2 0.0052 0.0391 0.0358
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0092 0.084 0.093
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0152 0.1526 0.1658
Brugia malayi Proteasome A-type and B-type family protein 0.0092 0.084 0.093
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.008
Toxoplasma gondii proteasome subunit alpha1, putative 0.0092 0.084 0.1372
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0253 0.0395
Plasmodium vivax proteasome subunit beta type-6, putative 0.0092 0.084 0.1398
Mycobacterium leprae Conserved hypothetical protein 0.0059 0.0475 0.0449
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0092 0.084 0.1456
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0134 0.132 0.2249
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0092 0.084 0.0808
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0141
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0901 1 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0362 0.0364
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.084 0.1456
Echinococcus granulosus Nuclear hormone receptor HR96 0.0238 0.2496 0.247
Giardia lamblia 20S proteasome alpha subunit 1 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0092 0.084 0.1398
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0092 0.084 0.0808
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0217 0.2258 0.2472
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0504 0.5513 0.9903
Brugia malayi Calcitonin receptor-like protein seb-1 0.0164 0.1664 0.1842
Brugia malayi ImpB/MucB/SamB family protein 0.0048 0.0341 0.0378
Echinococcus multilocularis 0.0059 0.0475 0.0442
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0092 0.084 0.0895
Brugia malayi nuclear hormone receptor family member odr-7 0.0238 0.2496 0.2764
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) cytochrome P450 0.0059 0.0475 0.0526
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0092 0.084 0.1456
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0092 0.084 0.093
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.1474 0.1445
Echinococcus granulosus neuropeptide s receptor 0.0027 0.0112 0.0078
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0118 0.015
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0027 0.0112 0.0141
Onchocerca volvulus 0.0027 0.0112 0.0074
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0059 0.0475 0.0796
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0059 0.0475 0.0796
Loa Loa (eye worm) hypothetical protein 0.0112 0.1075 0.119
Plasmodium vivax proteasome subunit beta type-1, putative 0.0347 0.373 0.6657
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0362 0.0364
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0159 0.0125
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0112 0.0078
Leishmania major GTP-binding protein, putative 0.0025 0.0088 0.006
Leishmania major proteasome alpha 1 subunit, putative 0.0092 0.084 0.0895
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0072 0.0038
Brugia malayi Proteasome A-type and B-type family protein 0.0092 0.084 0.093
Mycobacterium ulcerans lipase LipD 0.0038 0.0236 0.0363
Leishmania major hypothetical protein, conserved 0.0038 0.0236 0.0223
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0059 0.0475 0.0796
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0025 0.0088 0.0097
Brugia malayi Nuclear hormone receptor-like 1 0.0266 0.2819 0.3122
Schistosoma mansoni opsin-like receptor 0.0027 0.0112 0.0141
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0217 0.2258 0.402
Loa Loa (eye worm) hypothetical protein 0.0164 0.1664 0.1842
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0092 0.084 0.0895
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0059 0.0475 0.0796
Loa Loa (eye worm) cytochrome P450 family protein 0.0079 0.0697 0.0772
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0072 0.0038
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0362 0.0364
Echinococcus granulosus orexin receptor type 2 0.0027 0.0112 0.0078
Echinococcus multilocularis sex peptide receptor 0.0027 0.0112 0.0078
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0147 0.0125
Mycobacterium tuberculosis Conserved protein 0.0038 0.0236 0.0363
Loa Loa (eye worm) hypothetical protein 0.0048 0.0341 0.0378
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0112 0.0078
Schistosoma mansoni polycystin 1-related 0.0024 0.0072 0.0068
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0236 0.0223
Echinococcus granulosus nuclear receptor nhr 48 0.0238 0.2496 0.247
Brugia malayi latrophilin 2 splice variant baaae 0.0112 0.1075 0.119
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0236 0.0363
Mycobacterium ulcerans proteasome PrcB 0.0509 0.5566 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0504 0.5513 0.5497
Brugia malayi Nuclear hormone receptor-like 1 0.0504 0.5513 0.6104
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0362 0.0401
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0236 0.0363
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0092 0.084 0.1456
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0052 0.0391 0.0358
Schistosoma mansoni hypothetical protein 0.0052 0.0391 0.0645
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0141
Onchocerca volvulus 0.0027 0.0112 0.0074
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0147 0.0137
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0347 0.373 0.668
Mycobacterium tuberculosis Conserved protein 0.0038 0.0236 0.0363
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0059 0.0475 0.0796
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0362 0.0591
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0027
Echinococcus granulosus lamin dm0 0.0033 0.0171 0.0137
Schistosoma mansoni thyroid hormone receptor 0.0504 0.5513 0.9903
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0112 0.0125
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0509 0.5566 0.6148
Echinococcus granulosus importin subunit beta 1 0.0034 0.0191 0.0157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0504 0.5513 0.6104
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0112 0.0141
Echinococcus granulosus g protein coupled receptor 0.0027 0.0112 0.0078
Leishmania major proteasome alpha 3 subunit, putative 0.0092 0.084 0.0895
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0491 0.0507
Onchocerca volvulus 0.0027 0.0112 0.0074
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0294 0.0375
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0238 0.2496 0.247
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0504 0.5513 0.5497
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.2244 0.3994
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0092 0.084 0.0808
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Mycobacterium ulcerans hypothetical protein 0.0038 0.0236 0.0363
Echinococcus granulosus allatostatin A receptor 0.0027 0.0112 0.0078
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0217 0.2258 0.402
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0491 0.0825
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni growth hormone secretagogue receptor 0.0027 0.0112 0.0141
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0092 0.084 0.1398
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0238 0.2496 0.247
Trypanosoma cruzi cytochrome P450, putative 0.0079 0.0697 0.0737
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0118 0.0092
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0236 0.0363
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Onchocerca volvulus 0.0038 0.0236 0.0301
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0112 0.0078
Schistosoma mansoni ran 0.0025 0.0088 0.0097
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0092 0.084 0.1398
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0266 0.2819 0.3122
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0112 0.0141
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Onchocerca volvulus 0.0027 0.0112 0.0074
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0092 0.084 0.0895
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0152 0.1526 0.1658
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0092 0.084 0.1456
Brugia malayi Pre-SET motif family protein 0.022 0.2287 0.2533
Echinococcus granulosus ecdysone induced protein 78C 0.0504 0.5513 0.5497
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0236 0.0363
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0491 0.0735
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0118 0.015
Mycobacterium ulcerans proteasome PrcA 0.0092 0.084 0.1456
Trypanosoma brucei cytochrome P450, putative 0.0079 0.0697 0.0737
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0092 0.084 0.1456
Echinococcus granulosus somatostatin receptor 0.0027 0.0112 0.0078
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0238 0.2496 0.4455
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0112 0.0141
Onchocerca volvulus 0.0238 0.2496 0.4455
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0118 0.015
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0509 0.5566 1
Schistosoma mansoni importin beta-1 0.0034 0.0191 0.0283
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0504 0.5513 0.6104
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0092 0.084 0.0895
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0134 0.132 0.1429
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0509 0.5566 1
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0236 0.0363
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0059 0.0475 0.0796
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0238 0.2496 0.247
Brugia malayi Proteasome A-type and B-type family protein 0.0509 0.5566 0.6163
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0072 0.0038
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0092 0.084 0.1456
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0112 0.0078
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0112 0.0141
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0236 0.0363
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0217 0.2258 0.2472
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0092 0.084 0.1372
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0092 0.084 0.093
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0027 0.0112 0.0074
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0092 0.084 0.1398
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0504 0.5513 1
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0362 0.0591
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0025 0.0088 0.0054
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0059 0.0475 0.0796
Echinococcus multilocularis proteasome subunit alpha type 6 0.0092 0.084 0.0808
Schistosoma mansoni rab6-interacting 0.0024 0.0072 0.0068
Brugia malayi proteasome subunit beta type 1 0.0347 0.373 0.413
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0092 0.084 0.0895
Toxoplasma gondii proteasome subunit 0.0092 0.084 0.1372
Echinococcus granulosus hypothetical protein 0.0027 0.0112 0.0078
Giardia lamblia Proteasome subunit beta type 3 0.0092 0.084 0.1456
Schistosoma mansoni biogenic amine receptor 0.0027 0.0112 0.0141
Schistosoma mansoni intermediate filament proteins 0.0033 0.0171 0.0247
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0362 0.0591
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0491 0.0825
Onchocerca volvulus Protein ultraspiracle homolog 0.0504 0.5513 1
Leishmania major proteasome alpha 2 subunit, putative 0.0092 0.084 0.0895
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0052 0.0391 0.0358
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0092 0.084 0.0808
Leishmania major DNA polymerase eta, putative 0.0033 0.0181 0.0163
Brugia malayi proteasome subunit beta type 3 0.0092 0.084 0.093
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0092 0.084 0.0895
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0067 0.0557 0.0524
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0112 0.0125
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0059 0.0475 0.0796
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0159 0.0125
Brugia malayi Cytochrome P450 family protein 0.0059 0.0475 0.0526
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0112 0.0125
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0092 0.084 0.0895
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0092 0.084 0.093
Brugia malayi Dopamine receptor 0.0027 0.0112 0.0125
Brugia malayi steroid hormone receptor 0.0504 0.5513 0.6104
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0092 0.084 0.0808
Onchocerca volvulus 0.0033 0.0171 0.0182
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0253 0.033
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0092 0.084 0.1398
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0059 0.0475 0.0796
Echinococcus multilocularis serotonin receptor 0.0027 0.0112 0.0078
Echinococcus granulosus sex peptide receptor 0.0027 0.0112 0.0078
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0815 0.9031 1
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0092 0.084 0.0808
Echinococcus multilocularis survival motor neuron protein 1 0.0257 0.2716 0.2691
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi nuclear receptor NHR-88 0.0504 0.5513 0.6104
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni opsin-like receptor 0.0027 0.0112 0.0141
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0504 0.5513 0.5497
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Echinococcus multilocularis proteasome (prosome, macropain) 0.0509 0.5566 0.5551
Schistosoma mansoni survival motor neuron protein 0.0053 0.0397 0.0655
Toxoplasma gondii proteasome subunit beta type, putative 0.0509 0.5566 1
Brugia malayi proteasome subunit alpha type 6 0.0092 0.084 0.093
Brugia malayi intermediate filament protein 0.0033 0.0171 0.019
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0092 0.084 0.1456
Brugia malayi Proteasome subunit alpha type 7-1 0.0092 0.084 0.093
Loa Loa (eye worm) steroid hormone receptor 0.0504 0.5513 0.6104
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0362 0.0364
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0059 0.0475 0.049
Schistosoma mansoni hypothetical protein 0.0052 0.0391 0.0645
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0059 0.0475 0.0796
Echinococcus granulosus lamin 0.0033 0.0171 0.0137
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Trypanosoma brucei protein kinase, putative 0.0049 0.0362 0.0364
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0294 0.0375
Schistosoma mansoni nuclear hormone receptor 0.0238 0.2496 0.445
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0059 0.0475 0.0796
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0092 0.084 0.1398
Echinococcus multilocularis proteasome subunit alpha type 2 0.0092 0.084 0.0808
Plasmodium vivax proteasome subunit beta type-5, putative 0.0509 0.5566 1
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.3333 0.3691
Echinococcus granulosus Proteasome subunit alpha beta 0.0092 0.084 0.0808
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0362 0.0499
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0112 0.0125
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0072 0.0038
Brugia malayi orphan nuclear receptor NR2E1 0.0238 0.2496 0.2764
Echinococcus multilocularis snurportin 1 0.0366 0.395 0.3929
Onchocerca volvulus Neuropeptide F receptor homolog 0.0027 0.0112 0.0074
Leishmania major hypothetical protein, conserved 0.0152 0.1526 0.1658
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0509 0.5566 0.6148
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0092 0.084 0.0808
Echinococcus granulosus g protein coupled receptor 0.0027 0.0112 0.0078
Brugia malayi beta-lactamase 0.0038 0.0236 0.0261
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0033 0.0171 0.019
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0147 0.0137
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0092 0.084 0.1372
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0059 0.0475 0.0796
Toxoplasma gondii cytochrome p450 superfamily protein 0.0059 0.0475 0.0706
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0266 0.2819 0.3122
Giardia lamblia 20S proteasome alpha subunit 2 0.0092 0.084 0.1456
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0112 0.0125
Brugia malayi putative neuropeptide receptor 0.0027 0.0112 0.0125
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0238 0.2496 0.2764
Giardia lamblia Proteasome subunit beta type 1 0.0347 0.373 0.668
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0059 0.0475 0.0796
Schistosoma mansoni histamine h1 receptor 0.0027 0.0112 0.0141
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0112 0.0078
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0238 0.2496 0.247
Brugia malayi nuclear receptor NHR-67 0.0238 0.2496 0.2764
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Leishmania major DNA polymerase eta, putative 0.0048 0.0341 0.0341
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0236 0.0363
Plasmodium falciparum proteasome subunit beta type-5 0.0509 0.5566 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0362 0.0364
Echinococcus multilocularis nuclear receptor nhr 48 0.0238 0.2496 0.247
Onchocerca volvulus 0.0027 0.0112 0.0074
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.1474 0.2603
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Trypanosoma brucei DNA polymerase eta, putative 0.0048 0.0341 0.0341
Brugia malayi photoreceptor-specific nuclear receptor 0.0504 0.5513 0.6104
Schistosoma mansoni steroid hormone receptor ad4bp 0.0504 0.5513 0.9903
Echinococcus granulosus GTP binding nuclear protein Ran 0.0025 0.0088 0.0054
Plasmodium vivax proteasome subunit beta type-7, putative 0.0092 0.084 0.1398
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0504 0.5513 0.5497
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0491 0.0825
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0092 0.084 0.1456
Brugia malayi Muscleblind-like protein 0.0163 0.1643 0.182
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0236 0.0363
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0092 0.084 0.0808
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0059 0.0475 0.049
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0147 0.0107
Loa Loa (eye worm) hypothetical protein 0.0031 0.0159 0.0176
Schistosoma mansoni myosin xvIII 0.0027 0.0112 0.0141
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Echinococcus granulosus g protein coupled receptor 0.0027 0.0112 0.0078
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0092 0.084 0.0895
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0504 0.5513 0.5497
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0504 0.5513 0.9903
Schistosoma mansoni lipoxygenase 0.0067 0.0557 0.0945
Schistosoma mansoni lamin 0.0033 0.0171 0.0247
Brugia malayi proteasome subunit alpha type 2 0.0092 0.084 0.093
Brugia malayi hypothetical protein 0.002 0.0025 0.0028
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0141
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0236 0.0363
Toxoplasma gondii peptidase, T1 family protein 0.0092 0.084 0.1372
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0112 0.0078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Brugia malayi ecdysone receptor 0.0238 0.2496 0.2764
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0504 0.5513 0.6104
Brugia malayi ecdysteroid receptor 0.0504 0.5513 0.6104
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0059 0.0475 0.0796
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0147 0.0137
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0159 0.0225
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0134 0.132 0.2249
Toxoplasma gondii ABC1 family protein 0.0038 0.0236 0.0269
Leishmania major cytochrome p450-like protein 0.0079 0.0697 0.0737
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0141
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0112 0.0078
Brugia malayi RE15519p 0.0027 0.0112 0.0125
Leishmania major proteasome beta 5 subunit, putative 0.0509 0.5566 0.6148
Loa Loa (eye worm) latrophilin receptor protein 2 0.0052 0.0391 0.0433
Brugia malayi sulfakinin receptor protein 0.0027 0.0112 0.0125
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0112 0.0141
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0059 0.0475 0.049
Loa Loa (eye worm) hypothetical protein 0.0034 0.0191 0.0212
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0362 0.0591
Brugia malayi MAP kinase sur-1 0.0049 0.0362 0.0401
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0092 0.084 0.1456
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0509 0.5566 0.6163
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0366 0.395 0.4374
Trypanosoma cruzi cytochrome P450, putative 0.0079 0.0697 0.0737
Onchocerca volvulus 0.0027 0.0112 0.0074
Schistosoma mansoni nuclear receptor 0.0238 0.2496 0.445
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0141
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0171 0.019
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0112 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0504 0.5513 0.6104
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.1427 0.1398
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0112 0.0078
Brugia malayi Nuclear hormone receptor E75 0.0238 0.2496 0.2764
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0112 0.0078
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0059 0.0475 0.0796
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0134 0.132 0.129
Brugia malayi Cytochrome P450 family protein 0.0079 0.0697 0.0772
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0152 0.1526 0.1658
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0134 0.132 0.129
Brugia malayi hypothetical protein 0.0266 0.2819 0.3122
Mycobacterium ulcerans beta-lactamase 0.0038 0.0236 0.0363
Brugia malayi beta-lactamase family protein 0.0038 0.0236 0.0261
Schistosoma mansoni opsin-like receptor 0.0027 0.0112 0.0141
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0092 0.084 0.093
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0112 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Echinococcus granulosus snurportin 1 0.0366 0.395 0.3929
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Toxoplasma gondii HEAT repeat-containing protein 0.0034 0.0191 0.0187
Onchocerca volvulus 0.0038 0.0236 0.0301
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0112 0.0078
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0059 0.0475 0.0796
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0092 0.084 0.1456
Echinococcus granulosus FTZ F1 alpha 0.0504 0.5513 0.5497
Plasmodium vivax proteasome subunit beta type-2, putative 0.0217 0.2258 0.3979
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0236 0.0202
Brugia malayi neuropeptide F receptor 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0035 0.0038
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0509 0.5566 1
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0147 0.0125
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0504 0.5513 0.5497
Schistosoma mansoni nuclear hormone receptor 0.0504 0.5513 0.9903
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0092 0.084 0.1456
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0092 0.084 0.0895
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0059 0.0475 0.0796
Brugia malayi hypothetical protein 0.0266 0.2819 0.3122
Toxoplasma gondii proteasome subunit alpha type, putative 0.0092 0.084 0.1372
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0092 0.084 0.1456
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0059 0.0475 0.0796
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0052 0.0391 0.0433
Schistosoma mansoni hypothetical protein 0.0053 0.0397 0.0655
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0112 0.0078
Echinococcus granulosus cytochrome P450 2K1 0.0059 0.0475 0.0442
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0059 0.0475 0.0796
Loa Loa (eye worm) CYP4Cod1 0.0079 0.0697 0.0772
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0059 0.0475 0.0796
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0092 0.084 0.1398
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0112 0.0078
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0112 0.0141
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0112 0.0125
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0362 0.0364
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0092 0.084 0.0895
Mycobacterium leprae putative cytochrome p450 0.0059 0.0475 0.0449
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0217 0.2258 0.402
Echinococcus multilocularis musashi 0.0033 0.0171 0.0137
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0092 0.084 0.1456
Loa Loa (eye worm) acetyltransferase 0.0148 0.1474 0.1632
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0052 0.0391 0.0433
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0504 0.5513 0.5497
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0238 0.2496 0.445
Plasmodium vivax SET domain protein, putative 0.0031 0.0159 0.0158
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0238 0.2496 0.247
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0393 0.425 0.762
Brugia malayi neuropeptide F receptor 0.0027 0.0112 0.0125
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0112 0.0078
Echinococcus multilocularis FTZ F1 alpha 0.0504 0.5513 0.5497
Echinococcus granulosus subfamily T1A non peptidase ue 0.0092 0.084 0.0808
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Onchocerca volvulus 0.0504 0.5513 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0164 0.1664 0.1842
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0092 0.084 0.0895
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0164 0.1664 0.1842
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0236 0.0202
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0112 0.0078
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0417 0.4519 0.5004
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0141
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0266 0.2819 0.5034
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0092 0.084 0.1456
Giardia lamblia 20S proteasome alpha subunit 7 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0266 0.2819 0.3122
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0092 0.084 0.0808
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0236 0.0363
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0059 0.0475 0.049
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0112 0.0078
Onchocerca volvulus 0.0027 0.0112 0.0074
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi GnHR receptor homolog 0.0027 0.0112 0.0125
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0134 0.132 0.2272
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0294 0.0404
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0092 0.084 0.0895
Loa Loa (eye worm) hypothetical protein 0.0266 0.2819 0.3122
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0092 0.084 0.1456
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Brugia malayi hypothetical protein 0.0024 0.0072 0.008
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0112 0.0078
Schistosoma mansoni DNA polymerase eta 0.0048 0.0341 0.0554
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Trypanosoma brucei proteasome alpha 7 subunit 0.0092 0.084 0.0895
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0159 0.0129
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0181 0.0163
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0112 0.0078
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0491 0.0825
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0035 0.0038
Brugia malayi hypothetical protein 0.0238 0.2496 0.2764
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0112 0.0125
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0059 0.0475 0.0796
Brugia malayi Steroid receptor seven-up type 2 0.0504 0.5513 0.6104
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0112 0.0125
Trypanosoma cruzi Emopamil binding protein, putative 0.0152 0.1526 0.1658
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0112 0.0125
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0393 0.425 0.423
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0072 0.0038
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.1474 0.1632
Onchocerca volvulus 0.0152 0.1526 0.2673
Echinococcus multilocularis proteasome subunit beta type 6 0.0092 0.084 0.0808
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0052 0.0391 0.0358
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0112 0.0078
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Leishmania major proteasome beta-1 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni nuclear receptor nhr-48 0.0238 0.2496 0.445
Loa Loa (eye worm) hypothetical protein 0.0266 0.2819 0.3122
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0027 0.0112 0.0141
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0027 0.0112 0.0141
Brugia malayi Dopamine receptor protein 2 0.0027 0.0112 0.0125
Brugia malayi beta-lactamase family protein 0.0038 0.0236 0.0261
Loa Loa (eye worm) DR-78 0.0238 0.2496 0.2764
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0504 0.5513 0.6104
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0059 0.0475 0.0796
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0092 0.084 0.1456
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0362 0.0328
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0027 0.0112 0.0141
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0236 0.0363
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0078
Schistosoma mansoni hypothetical protein 0.0052 0.0391 0.0645
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0504 0.5513 0.6104
Brugia malayi Nuclear hormone receptor-like 1 0.0266 0.2819 0.3122
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0491 0.0458
Trichomonas vaginalis set domain proteins, putative 0.025 0.2631 0.4693
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0092 0.084 0.0808
Onchocerca volvulus 0.0053 0.0397 0.0597
Toxoplasma gondii proteasome beta subunit 0.0092 0.084 0.1372
Plasmodium vivax proteasome subunit beta type-3, putative 0.0092 0.084 0.1398
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0112 0.0078
Onchocerca volvulus 0.0027 0.0112 0.0074
Echinococcus granulosus survival motor neuron protein 1 0.0257 0.2716 0.2691
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0078
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0171 0.019
Giardia lamblia Proteasome subunit beta type 2 0.0217 0.2258 0.402
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0092 0.084 0.093
Echinococcus granulosus RUN 0.0024 0.0072 0.0038
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0092 0.084 0.1398
Leishmania major hypothetical protein, conserved 0.003 0.0147 0.0125
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0033 0.0181 0.0169
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0815 0.9031 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0112 0.0078
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0112 0.0078
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0238 0.2496 0.2764
Leishmania major C-8 sterol isomerase-like protein 0.0815 0.9031 1
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0347 0.373 0.6657
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0217 0.2258 0.2231
Schistosoma mansoni retinoic acid receptor RXR 0.0504 0.5513 0.9903
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Leishmania major proteasome beta 3 subunit, putative 0.0092 0.084 0.0895
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0112 0.0125
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0236 0.0363
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0504 0.5513 0.6104
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Echinococcus multilocularis muscleblind protein 1 0.0163 0.1643 0.1614
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0191 0.0174
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0092 0.084 0.093
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0159 0.0225
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0393 0.425 0.423
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0059 0.0475 0.0796
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0112 0.0125
Echinococcus multilocularis somatostatin receptor 0.0027 0.0112 0.0078
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0092 0.084 0.0895
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0059 0.0475 0.0796
Schistosoma mansoni lamin 0.0033 0.0171 0.0247
Echinococcus granulosus fmrfamide receptor 0.0027 0.0112 0.0078
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0092 0.084 0.1456
Brugia malayi G protein-coupled receptor 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Brugia malayi cytochrome P450 0.0059 0.0475 0.0526
Schistosoma mansoni hypothetical protein 0.0112 0.1075 0.188
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0112 0.0141
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0509 0.5566 0.6148
Onchocerca volvulus 0.0027 0.0112 0.0074
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0347 0.373 0.3708
Brugia malayi conserved hypotetical protein 0.0238 0.2496 0.2764
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Onchocerca volvulus 0.025 0.2631 0.4703
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Brugia malayi nuclear hormone receptor 0.0238 0.2496 0.2764
Echinococcus granulosus neuropeptide receptor A26 0.0027 0.0112 0.0078
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0141
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Echinococcus multilocularis geminin 0.0205 0.2119 0.2092
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0092 0.084 0.1456
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0092 0.084 0.1456
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0112 0.0125
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0088 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Schistosoma mansoni adenoreceptor 0.0027 0.0112 0.0141
Echinococcus granulosus proteasome subunit beta t family 0.0092 0.084 0.0808
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0112 0.0078
Brugia malayi Dopamine receptor protein 1 0.0027 0.0112 0.0125
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0092 0.084 0.0895
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0112 0.0078
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0217 0.2258 0.3961
Loa Loa (eye worm) hypothetical protein 0.0815 0.9031 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi RNA, U transporter 1 0.0098 0.0907 0.1005
Schistosoma mansoni rab6-interacting 0.0024 0.0072 0.0068
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0092 0.084 0.1398
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0079 0.0697 0.1198
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0509 0.5566 1
Echinococcus granulosus neuropeptide receptor 0.0027 0.0112 0.0078
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0491 0.0458
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0059 0.0475 0.0796
Echinococcus multilocularis thyroid hormone receptor alpha 0.0504 0.5513 0.5497
Plasmodium falciparum proteasome subunit beta type-4 0.0092 0.084 0.1398
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0266 0.2819 0.2794
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Schistosoma mansoni hypothetical protein 0.0052 0.0391 0.0645
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0504 0.5513 0.6104
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.2244 0.3994
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0092 0.084 0.1134
Brugia malayi Proteasome subunit alpha type 1 0.0092 0.084 0.093
Echinococcus granulosus Nuclear hormone receptor HR96 0.0238 0.2496 0.247
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0112 0.0078
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0217 0.2258 0.402
Trichomonas vaginalis ran, putative 0.0025 0.0088 0.0097
Schistosoma mansoni ran 0.0025 0.0088 0.0097
Onchocerca volvulus 0.0033 0.0171 0.0182
Brugia malayi tailless protein 0.0238 0.2496 0.2764
Brugia malayi nuclear hormone receptor family member nhr-6 0.0238 0.2496 0.2764
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0362 0.0591
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0504 0.5513 0.6104
Echinococcus granulosus dna polymerase eta 0.0048 0.0341 0.0308
Schistosoma mansoni hypothetical protein 0.0205 0.2119 0.3768
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0025 0.0088 0.0098
Brugia malayi Proteasome A-type and B-type family protein 0.0092 0.084 0.093
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0092 0.084 0.1456
Brugia malayi proteasome subunit alpha type 4 0.0092 0.084 0.093
Mycobacterium tuberculosis Conserved protein 0.0038 0.0236 0.0363
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0059 0.0475 0.0796
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0509 0.5566 1
Brugia malayi hypothetical protein 0.003 0.0147 0.0163
Schistosoma mansoni hypothetical protein 0.0059 0.0475 0.0796
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0217 0.2258 0.3979
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0236 0.0223
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0509 0.5566 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0397 0.0439
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi nuclear receptor RXR 0.0266 0.2819 0.3122
Schistosoma mansoni biogenic amine receptor 0.0027 0.0112 0.0141
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0092 0.084 0.1456
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0092 0.084 0.0895
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0236 0.0223
Giardia lamblia 20S proteasome alpha subunit 5 0.0092 0.084 0.1456
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0112 0.0078
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0092 0.084 0.1398
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0092 0.084 0.1456
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0347 0.373 0.4107
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0191 0.0174
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0112 0.0078
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Echinococcus granulosus proteasome subunit alpha type 2 0.0092 0.084 0.0808
Onchocerca volvulus 0.0027 0.0112 0.0074
Onchocerca volvulus Bile acid receptor homolog 0.0504 0.5513 1
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0092 0.084 0.0808
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0059 0.0475 0.0796
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0294 0.026
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0092 0.084 0.1456
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0112 0.0078
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0347 0.373 0.668
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0236 0.0363
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0112 0.0078
Schistosoma mansoni nuclear receptor 0.0238 0.2496 0.445
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0266 0.2819 0.2794
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0092 0.084 0.1456
Schistosoma mansoni hypothetical protein 0.0024 0.0072 0.0068
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0347 0.373 0.4107
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0092 0.084 0.093
Trypanosoma brucei proteasome beta 6 subunit 0.0347 0.373 0.4107
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0141
Loa Loa (eye worm) proteasome subunit beta type 1 0.0347 0.373 0.413
Echinococcus granulosus neuropeptide receptor 0.0027 0.0112 0.0078
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0236 0.0363
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0217 0.2258 0.2231
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Onchocerca volvulus 0.0027 0.0112 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0362 0.0591
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0159 0.0225
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0112 0.0078
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0027 0.0112 0.0078
Trypanosoma brucei proteasome beta 7 subunit 0.0092 0.084 0.0895
Loa Loa (eye worm) nuclear receptor NHR-67 0.0238 0.2496 0.2764
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0092 0.084 0.1456
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.022 0.2287 0.2533
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi AKH receptor 0.0027 0.0112 0.0125
Leishmania major proteasome beta 2 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni cytochrome P450 0.0059 0.0475 0.0796
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0092 0.0845 0.1465
Brugia malayi proteasome subunit alpha type 1 0.0092 0.084 0.093
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.2119 0.3762
Echinococcus multilocularis neuropeptide receptor A26 0.0027 0.0112 0.0078
Loa Loa (eye worm) cytochrome P450 family protein 0.0079 0.0697 0.0772
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0236 0.0298
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0052 0.0391 0.0358
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0092 0.084 0.0895
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0092 0.084 0.1398
Brugia malayi proteasome subunit beta type 2 0.0217 0.2258 0.2501
Echinococcus multilocularis muscleblind protein 0.0163 0.1643 0.1614
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0238 0.2496 0.4455
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0059 0.0475 0.0796
Giardia lamblia 20S proteasome alpha subunit 4 0.0092 0.084 0.1456
Brugia malayi Nuclear hormone receptor E75 0.0238 0.2496 0.2764
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0504 0.5513 0.9903
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Onchocerca volvulus 0.0027 0.0112 0.0074
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Brugia malayi nuclear hormone receptor 0.0504 0.5513 0.6104
Leishmania major proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Onchocerca volvulus 0.0027 0.0112 0.0074
Onchocerca volvulus Notchless protein homolog 0.0092 0.084 0.1411
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0112 0.0078
Trypanosoma brucei C-8 sterol isomerase, putative 0.0815 0.9031 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0025 0.0088 0.003
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0092 0.084 0.1456
Echinococcus multilocularis neuropeptide s receptor 0.0027 0.0112 0.0078
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0504 0.5513 0.5497
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0027 0.0112 0.0141
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0362 0.0328
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0504 0.5513 0.5497
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0504 0.5513 0.6104
Plasmodium vivax proteasome subunit beta type-4, putative 0.0092 0.084 0.1398
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0146 0.0112
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0134 0.132 0.1429
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0347 0.373 0.4107
Brugia malayi Doublecortin family protein 0.0024 0.0072 0.008
Loa Loa (eye worm) hypothetical protein 0.0257 0.2716 0.3008
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0504 0.5513 0.5497
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0347 0.373 0.6647
Entamoeba histolytica hypothetical protein 0.0028 0.0118 0.015
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0059 0.0475 0.0796
Trypanosoma brucei Emopamil binding protein, putative 0.0152 0.1526 0.1658
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0112 0.0141
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0092 0.084 0.1456
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0504 0.5513 0.5497
Brugia malayi Importin beta-1 subunit 0.0034 0.0191 0.0212
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0059 0.0475 0.0796
Schistosoma mansoni thyroid hormone receptor 0.0504 0.5513 0.9903
Toxoplasma gondii heat shock protein hslv, putative 0.0092 0.084 0.1372
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Schistosoma mansoni lipoxygenase 0.0024 0.0072 0.0068
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0504 0.5513 0.9903
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0092 0.084 0.0895
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0504 0.5513 0.5497
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Brugia malayi Serotonin receptor 0.0027 0.0112 0.0125
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0025 0.0088 0.006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0491 0.0825
Schistosoma mansoni hypothetical protein 0.0205 0.2119 0.3768
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0266 0.2819 0.5034
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0092 0.084 0.1398
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Brugia malayi Cytochrome P450 family protein 0.0059 0.0475 0.0526
Loa Loa (eye worm) beta-lactamase 0.0038 0.0236 0.0261
Brugia malayi Cytochrome P450 family protein 0.0079 0.0697 0.0772
Echinococcus multilocularis importin subunit beta 1 0.0034 0.0191 0.0157
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0134 0.132 0.1429
Trypanosoma cruzi Emopamil binding protein, putative 0.0152 0.1526 0.1658
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0171 0.019
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0092 0.084 0.0895
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0504 0.5513 0.6104
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.084 0.1456
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0092 0.084 0.0808
Giardia lamblia 20S proteasome alpha subunit 6 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0347 0.373 0.668
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0112 0.0141
Brugia malayi Latrophilin receptor protein 2 0.0052 0.0391 0.0433
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0059 0.0475 0.0796
Leishmania major cytochrome p450-like protein 0.0059 0.0475 0.049
Onchocerca volvulus 0.0027 0.0112 0.0074
Onchocerca volvulus 0.0027 0.0112 0.0074
Echinococcus granulosus proteasome subunit alpha type 6 0.0092 0.084 0.0808
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0092 0.084 0.1398
Echinococcus multilocularis serotonin receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) proteasome subunit beta type 2 0.0217 0.2258 0.2501
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0475 0.0526
Echinococcus multilocularis lamin dm0 0.0033 0.0171 0.0137
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0393 0.425 0.4705
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0088 0.006
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0112 0.0078
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0112 0.0078
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0112 0.0078
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0504 0.5513 0.6104
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0092 0.084 0.093
Echinococcus granulosus intermediate filament protein 0.0033 0.0171 0.0137
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni neuropeptide f receptor 76f 0.0027 0.0112 0.0141
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0159 0.0125
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0238 0.2496 0.247

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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