Detailed information for compound 576756

Basic information

Technical information
  • TDR Targets ID: 576756
  • Name: [(2R)-3-(4-acetamidophenoxy)-2-hydroxy-propyl ]-isopropyl-ammonium
  • MW: 267.344 | Formula: C14H23N2O3+
  • H donors: 3 H acceptors: 2 LogP: 0.82 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@@H](COc1ccc(cc1)NC(=O)C)C[NH2+]C(C)C
  • InChi: 1S/C14H22N2O3/c1-10(2)15-8-13(18)9-19-14-6-4-12(5-7-14)16-11(3)17/h4-7,10,13,15,18H,8-9H2,1-3H3,(H,16,17)/p+1/t13-/m1/s1
  • InChiKey: DURULFYMVIFBIR-CYBMUJFWSA-O  

Network

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Synonyms

  • [(2R)-3-(4-acetamidophenoxy)-2-hydroxypropyl]-isopropylammonium
  • [(2R)-3-(4-acetamidophenoxy)-2-hydroxy-propyl]-propan-2-yl-azanium
  • [(2R)-3-(4-acetamidophenoxy)-2-hydroxypropyl]-propan-2-ylazanium
  • Practolol
  • ZINC00000652

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0112 0.0078
Brugia malayi MAP kinase sur-1 0.0049 0.0362 0.0401
Brugia malayi Pre-SET motif family protein 0.022 0.2287 0.2533
Leishmania major proteasome beta-1 subunit, putative 0.0092 0.084 0.0895
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0092 0.084 0.0895
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0118 0.015
Brugia malayi Serotonin receptor 0.0027 0.0112 0.0125
Leishmania major proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0059 0.0475 0.0796
Onchocerca volvulus 0.0027 0.0112 0.0074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0092 0.084 0.1456
Loa Loa (eye worm) cytochrome P450 family protein 0.0079 0.0697 0.0772
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0112 0.0125
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0059 0.0475 0.0796
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0072 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0059 0.0475 0.0796
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0504 0.5513 0.5497
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0059 0.0475 0.049
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0236 0.0223
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0362 0.0591
Loa Loa (eye worm) hypothetical protein 0.0417 0.4519 0.5004
Brugia malayi larval opioid receptor 0.0027 0.0112 0.0125
Echinococcus granulosus cytochrome P450 2K1 0.0059 0.0475 0.0442
Echinococcus multilocularis somatostatin receptor 0.0027 0.0112 0.0078
Brugia malayi Latrophilin receptor protein 2 0.0052 0.0391 0.0433
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0504 0.5513 0.6104
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0112 0.0078
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0059 0.0475 0.0796
Schistosoma mansoni steroid hormone receptor ad4bp 0.0504 0.5513 0.9903
Loa Loa (eye worm) hypothetical protein 0.0266 0.2819 0.3122
Entamoeba histolytica hypothetical protein 0.0028 0.0118 0.015
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0092 0.084 0.0895
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Schistosoma mansoni opsin-like receptor 0.0027 0.0112 0.0141
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Brugia malayi Dopamine receptor protein 1 0.0027 0.0112 0.0125
Leishmania major cytochrome p450-like protein 0.0059 0.0475 0.049
Loa Loa (eye worm) proteasome subunit beta type 3 0.0092 0.084 0.093
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0059 0.0475 0.0796
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0059 0.0475 0.0796
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0159 0.0225
Brugia malayi sulfakinin receptor protein 0.0027 0.0112 0.0125
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0025 0.0088 0.0097
Brugia malayi proteasome subunit alpha type 2 0.0092 0.084 0.093
Echinococcus multilocularis lamin dm0 0.0033 0.0171 0.0137
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0164 0.1664 0.1842
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0236 0.0363
Brugia malayi nuclear hormone receptor 0.0504 0.5513 0.6104
Giardia lamblia 20S proteasome alpha subunit 5 0.0092 0.084 0.1456
Brugia malayi G-protein coupled receptor 0.0027 0.0112 0.0125
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0072 0.0038
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0079 0.0697 0.1198
Loa Loa (eye worm) hypothetical protein 0.0815 0.9031 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0362 0.0328
Giardia lamblia 20S proteasome alpha subunit 1 0.0092 0.084 0.1456
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0112 0.0125
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0112 0.0078
Giardia lamblia Proteasome subunit beta type 2 0.0217 0.2258 0.402
Loa Loa (eye worm) hypothetical protein 0.0163 0.1643 0.182
Mycobacterium tuberculosis Conserved protein 0.0038 0.0236 0.0363
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0504 0.5513 0.6104
Brugia malayi steroid hormone receptor 0.0504 0.5513 0.6104
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0092 0.084 0.0895
Echinococcus granulosus proteasome subunit beta type 6 0.0092 0.084 0.0808
Echinococcus multilocularis thyroid hormone receptor alpha 0.0504 0.5513 0.5497
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0025 0.0088 0.006
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0025 0.0088 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0504 0.5513 0.6104
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0236 0.0202
Leishmania major DNA polymerase eta, putative 0.0048 0.0341 0.0341
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0092 0.084 0.1456
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0236 0.0363
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Loa Loa (eye worm) hypothetical protein 0.003 0.0147 0.0163
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0092 0.084 0.1398
Brugia malayi RNA, U transporter 1 0.0098 0.0907 0.1005
Echinococcus granulosus proteasome subunit beta type 7 0.0092 0.084 0.0808
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.3333 0.3691
Echinococcus granulosus lamin dm0 0.0033 0.0171 0.0137
Schistosoma mansoni nuclear hormone receptor 0.0504 0.5513 0.9903
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0159 0.0125
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0112 0.0078
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0509 0.5566 0.6148
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0238 0.2496 0.4455
Brugia malayi Nuclear hormone receptor E75 0.0238 0.2496 0.2764
Trypanosoma cruzi cytochrome P450, putative 0.0079 0.0697 0.0737
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0159 0.0225
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0491 0.0507
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0092 0.084 0.1398
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0112 0.0078
Brugia malayi Nuclear hormone receptor-like 1 0.0504 0.5513 0.6104
Onchocerca volvulus 0.0031 0.0159 0.016
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0362 0.0328
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0504 0.5513 0.6104
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0159 0.0125
Loa Loa (eye worm) hypothetical protein 0.0163 0.1643 0.182
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0092 0.084 0.1456
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0236 0.0363
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0238 0.2496 0.247
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0509 0.5566 1
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Echinococcus multilocularis GPCR, family 2 0.0052 0.0391 0.0358
Leishmania major hypothetical protein, conserved 0.003 0.0147 0.0125
Brugia malayi Muscleblind-like protein 0.0163 0.1643 0.182
Schistosoma mansoni retinoic acid receptor RXR 0.0504 0.5513 0.9903
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0475 0.0526
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0112 0.0078
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0092 0.084 0.0895
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0362 0.0364
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Brugia malayi Cytochrome P450 family protein 0.0059 0.0475 0.0526
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0141
Loa Loa (eye worm) hypothetical protein 0.0164 0.1664 0.1842
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0217 0.2258 0.3979
Loa Loa (eye worm) CYP4Cod1 0.0079 0.0697 0.0772
Echinococcus multilocularis serotonin receptor 0.0027 0.0112 0.0078
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0059 0.0475 0.0796
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0294 0.026
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0092 0.084 0.093
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0217 0.2258 0.402
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0236 0.0363
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0072 0.008
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0504 0.5513 0.6104
Echinococcus granulosus GTP binding nuclear protein Ran 0.0025 0.0088 0.0054
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0092 0.084 0.1456
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0092 0.084 0.1456
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0341 0.0341
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0059 0.0475 0.0796
Loa Loa (eye worm) hypothetical protein 0.0112 0.1075 0.119
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0059 0.0475 0.0796
Plasmodium vivax proteasome subunit beta type-1, putative 0.0347 0.373 0.6657
Brugia malayi Cytochrome P450 family protein 0.0079 0.0697 0.0772
Trypanosoma cruzi Emopamil binding protein, putative 0.0152 0.1526 0.1658
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.084 0.1456
Brugia malayi nuclear hormone receptor 0.0238 0.2496 0.2764
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0362 0.0328
Giardia lamblia 20S proteasome alpha subunit 7 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0092 0.084 0.1456
Toxoplasma gondii cytochrome p450 superfamily protein 0.0059 0.0475 0.0706
Leishmania major DNA polymerase eta, putative 0.0033 0.0181 0.0163
Leishmania major hypothetical protein, conserved 0.0038 0.0236 0.0223
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.008
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0092 0.084 0.0895
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0092 0.084 0.1456
Trichomonas vaginalis set domain proteins, putative 0.025 0.2631 0.4693
Loa Loa (eye worm) hypothetical protein 0.0266 0.2819 0.3122
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0092 0.084 0.093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Brugia malayi hypothetical protein 0.0266 0.2819 0.3122
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0092 0.084 0.093
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0217 0.2258 0.2472
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0347 0.373 0.6657
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Leishmania major proteasome beta 2 subunit, putative 0.0217 0.2258 0.2472
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0266 0.2819 0.3122
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0112 0.0141
Leishmania major hypothetical protein, conserved 0.0152 0.1526 0.1658
Leishmania major C-8 sterol isomerase-like protein 0.0815 0.9031 1
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0092 0.084 0.0808
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0491 0.0825
Onchocerca volvulus Protein ultraspiracle homolog 0.0504 0.5513 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0504 0.5513 0.9903
Schistosoma mansoni adenoreceptor 0.0027 0.0112 0.0141
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0112 0.0078
Schistosoma mansoni thyroid hormone receptor 0.0504 0.5513 0.9903
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0266 0.2819 0.5034
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0092 0.084 0.1398
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi conserved hypotetical protein 0.0238 0.2496 0.2764
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0027 0.0112 0.0141
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Brugia malayi proteasome subunit beta type 2 0.0217 0.2258 0.2501
Echinococcus granulosus sex peptide receptor 0.0027 0.0112 0.0078
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0092 0.084 0.0895
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0362 0.0499
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Leishmania major proteasome beta 3 subunit, putative 0.0092 0.084 0.0895
Brugia malayi nuclear hormone receptor family member nhr-6 0.0238 0.2496 0.2764
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0504 0.5513 0.5497
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0112 0.0078
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0112 0.0078
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0092 0.084 0.0895
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0092 0.084 0.0895
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0092 0.084 0.0895
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0347 0.373 0.4107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0504 0.5513 0.6104
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0504 0.5513 0.6104
Echinococcus multilocularis survival motor neuron protein 1 0.0257 0.2716 0.2691
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0027 0.0112 0.0141
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0092 0.084 0.1398
Brugia malayi Nuclear hormone receptor E75 0.0238 0.2496 0.2764
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0092 0.084 0.093
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0027 0.0112 0.0141
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0112 0.0078
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0347 0.373 0.4107
Entamoeba histolytica Ran family GTPase 0.0025 0.0088 0.0097
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0112 0.0141
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0112 0.0141
Trypanosoma cruzi 20S proteasome subunit 0.0217 0.2258 0.2472
Leishmania major proteasome alpha 2 subunit, putative 0.0092 0.084 0.0895
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0112 0.0125
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Brugia malayi Cytochrome P450 family protein 0.0079 0.0697 0.0772
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0092 0.084 0.0808
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0092 0.084 0.1456
Schistosoma mansoni hypothetical protein 0.0366 0.395 0.7079
Brugia malayi latrophilin 2 splice variant baaae 0.0112 0.1075 0.119
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0092 0.084 0.0895
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0362 0.0591
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0504 0.5513 0.6104
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0171 0.019
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0059 0.0475 0.0796
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0059 0.0475 0.0796
Loa Loa (eye worm) cytochrome P450 0.0059 0.0475 0.0526
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0112 0.0078
Brugia malayi hypothetical protein 0.002 0.0025 0.0028
Echinococcus granulosus survival motor neuron protein 1 0.0257 0.2716 0.2691
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0092 0.084 0.1398
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0366 0.395 0.4374
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0112 0.0078
Giardia lamblia 20S proteasome alpha subunit 4 0.0092 0.084 0.1456
Onchocerca volvulus 0.0027 0.0112 0.0074
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0159 0.0225
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0509 0.5566 0.6148
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0491 0.0458
Schistosoma mansoni DNA polymerase eta 0.0048 0.0341 0.0554
Loa Loa (eye worm) DR-78 0.0238 0.2496 0.2764
Echinococcus granulosus geminin 0.0205 0.2119 0.2092
Onchocerca volvulus 0.0027 0.0112 0.0074
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0152 0.1526 0.1658
Brugia malayi Proteasome A-type and B-type family protein 0.0509 0.5566 0.6163
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0092 0.084 0.0895
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0236 0.0363
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0253 0.0395
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0092 0.084 0.0808
Leishmania major proteasome beta 2 subunit, putative 0.0092 0.084 0.0895
Echinococcus multilocularis proteasome subunit beta type 6 0.0092 0.084 0.0808
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Leishmania major proteasome beta 5 subunit, putative 0.0509 0.5566 0.6148
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0059 0.0475 0.0796
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0059 0.0475 0.0796
Echinococcus multilocularis importin subunit beta 1 0.0034 0.0191 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0504 0.5513 0.6104
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0294 0.0404
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0092 0.084 0.1398
Brugia malayi hypothetical protein 0.0266 0.2819 0.3122
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0393 0.425 0.4705
Echinococcus multilocularis proteasome subunit beta type 7 0.0092 0.084 0.0808
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0059 0.0475 0.049
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0491 0.0825
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0217 0.2258 0.402
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0072 0.0038
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0059 0.0475 0.0796
Brugia malayi hypothetical protein 0.0238 0.2496 0.2764
Onchocerca volvulus 0.0027 0.0112 0.0074
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.1474 0.2603
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0092 0.084 0.1398
Brugia malayi nuclear receptor NHR-88 0.0504 0.5513 0.6104
Giardia lamblia Proteasome subunit beta type 1 0.0347 0.373 0.668
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0059 0.0475 0.0796
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0059 0.0475 0.0796
Brugia malayi neuropeptide F receptor 0.0027 0.0112 0.0125
Brugia malayi Dopamine receptor 0.0027 0.0112 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Onchocerca volvulus 0.0027 0.0112 0.0074
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Onchocerca volvulus 0.025 0.2631 0.4703
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0092 0.084 0.0895
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus granulosus ecdysone induced protein 78C 0.0504 0.5513 0.5497
Trypanosoma brucei Emopamil binding protein, putative 0.0152 0.1526 0.1658
Echinococcus multilocularis proteasome subunit alpha type 2 0.0092 0.084 0.0808
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0171 0.019
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0092 0.084 0.1456
Loa Loa (eye worm) steroid hormone receptor 0.0504 0.5513 0.6104
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0092 0.084 0.0808
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0052 0.0391 0.0358
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0217 0.2258 0.402
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0244 0.257 0.4583
Echinococcus granulosus GPCR family 2 0.0052 0.0391 0.0358
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0253 0.0395
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0112 0.0078
Onchocerca volvulus 0.0033 0.0171 0.0182
Brugia malayi orphan nuclear receptor NR2E1 0.0238 0.2496 0.2764
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0092 0.084 0.1398
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0362 0.0364
Leishmania major cytochrome p450-like protein 0.0079 0.0697 0.0737
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0059 0.0475 0.0796
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0504 0.5513 0.6104
Loa Loa (eye worm) hypothetical protein 0.0257 0.2716 0.3008
Echinococcus granulosus allatostatin A receptor 0.0027 0.0112 0.0078
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0092 0.084 0.0808
Onchocerca volvulus 0.0027 0.0112 0.0074
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0112 0.0078
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0112 0.0078
Brugia malayi putative neuropeptide receptor 0.0027 0.0112 0.0125
Plasmodium vivax proteasome subunit beta type-7, putative 0.0092 0.084 0.1398
Toxoplasma gondii HEAT repeat-containing protein 0.0034 0.0191 0.0187
Toxoplasma gondii proteasome subunit alpha1, putative 0.0092 0.084 0.1372
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0141
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Echinococcus multilocularis proteasome (prosome, macropain) 0.0509 0.5566 0.5551
Trichomonas vaginalis esterase, putative 0.0038 0.0236 0.0363
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0504 0.5513 0.6104
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0236 0.0363
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0025 0.0088 0.0054
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0112 0.0125
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0112 0.0125
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0092 0.084 0.0895
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0092 0.084 0.0808
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0141
Brugia malayi neuropeptide F receptor 0.0027 0.0112 0.0125
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0078
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0112 0.0125
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0504 0.5513 0.5497
Onchocerca volvulus 0.0027 0.0112 0.0074
Schistosoma mansoni nuclear receptor nhr-48 0.0238 0.2496 0.445
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Echinococcus multilocularis RUN 0.0024 0.0072 0.0038
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0112 0.0078
Brugia malayi beta-lactamase family protein 0.0038 0.0236 0.0261
Schistosoma mansoni rab6-interacting 0.0024 0.0072 0.0068
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0059 0.0475 0.0796
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0504 0.5513 0.5497
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0147 0.0125
Onchocerca volvulus 0.0238 0.2496 0.4455
Leishmania major proteasome alpha 1 subunit, putative 0.0092 0.084 0.0895
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0236 0.0261
Brugia malayi hypothetical protein 0.0024 0.0072 0.008
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0092 0.084 0.0895
Leishmania major proteasome alpha 3 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni intermediate filament proteins 0.0033 0.0171 0.0247
Loa Loa (eye worm) hypothetical protein 0.0032 0.0164 0.0182
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi G protein-coupled receptor 0.0027 0.0112 0.0125
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0134 0.132 0.2249
Schistosoma mansoni nuclear receptor 0.0238 0.2496 0.445
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0092 0.084 0.093
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0112 0.0141
Brugia malayi nuclear receptor RXR 0.0238 0.2496 0.2764
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.2119 0.3768
Echinococcus granulosus serotonin receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni hypothetical protein 0.0053 0.0397 0.0655
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Trypanosoma brucei proteasome alpha 7 subunit 0.0092 0.084 0.0895
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0092 0.0845 0.1465
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0236 0.0363
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0092 0.084 0.1398
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Echinococcus multilocularis neuropeptide receptor A26 0.0027 0.0112 0.0078
Echinococcus multilocularis sex peptide receptor 0.0027 0.0112 0.0078
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.084 0.1456
Brugia malayi 20S proteasome alpha5 subunit 0.0092 0.084 0.093
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0294 0.0469
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus granulosus neuropeptide s receptor 0.0027 0.0112 0.0078
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0236 0.0202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0504 0.5513 0.6104
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0112 0.0078
Echinococcus granulosus Nuclear hormone receptor HR96 0.0238 0.2496 0.247
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0112 0.0078
Onchocerca volvulus 0.0033 0.0171 0.0182
Brugia malayi Calcitonin receptor-like protein seb-1 0.0164 0.1664 0.1842
Brugia malayi Importin beta-1 subunit 0.0034 0.0191 0.0212
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0504 0.5513 0.6104
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.1427 0.1398
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0217 0.2258 0.402
Plasmodium falciparum proteasome subunit beta type-5 0.0509 0.5566 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0504 0.5513 0.6104
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0092 0.084 0.0895
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus granulosus orexin receptor type 2 0.0027 0.0112 0.0078
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0347 0.373 0.668
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0059 0.0475 0.0796
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0509 0.5566 1
Onchocerca volvulus 0.0027 0.0112 0.0074
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0141
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0092 0.084 0.1398
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0112 0.0125
Echinococcus granulosus g protein coupled receptor 0.0027 0.0112 0.0078
Toxoplasma gondii proteasome beta subunit 0.0092 0.084 0.1372
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0491 0.0825
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0362 0.0364
Schistosoma mansoni opsin-like receptor 0.0027 0.0112 0.0141
Schistosoma mansoni biogenic amine receptor 0.0027 0.0112 0.0141
Brugia malayi Proteasome A-type and B-type family protein 0.0092 0.084 0.093
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0171 0.019
Schistosoma mansoni thyroid hormone receptor 0.0504 0.5513 0.9903
Trypanosoma brucei C-8 sterol isomerase, putative 0.0815 0.9031 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0027 0.0112 0.0141
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0238 0.2496 0.247
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0092 0.084 0.1456
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0092 0.084 0.1456
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0112 0.0141
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0347 0.373 0.6647
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0504 0.5513 0.6104
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0059 0.0475 0.0796
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0112 0.0078
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0059 0.0475 0.049
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0112 0.0078
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0092 0.084 0.1456
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0092 0.084 0.1456
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0052 0.0391 0.0358
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus multilocularis lamin 0.0033 0.0171 0.0137
Toxoplasma gondii heat shock protein hslv, putative 0.0092 0.084 0.1372
Brugia malayi hypothetical protein 0.0238 0.2496 0.2764
Trichomonas vaginalis ran, putative 0.0025 0.0088 0.0097
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0059 0.0475 0.0796
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0294 0.0375
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0092 0.084 0.1398
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0146 0.0112
Loa Loa (eye worm) hypothetical protein 0.0034 0.0191 0.0212
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.2244 0.3994
Schistosoma mansoni myosin xvIII 0.0027 0.0112 0.0141
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0134 0.132 0.2249
Brugia malayi hypothetical protein 0.0257 0.2716 0.3008
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0092 0.084 0.0895
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0112 0.0125
Echinococcus multilocularis muscleblind protein 1 0.0163 0.1643 0.1614
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0504 0.5513 0.6104
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0112 0.0078
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0112 0.0125
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0491 0.0825
Echinococcus multilocularis FTZ F1 alpha 0.0504 0.5513 0.5497
Onchocerca volvulus 0.0053 0.0397 0.0597
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0033 0.0171 0.019
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0112 0.0078
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0059 0.0475 0.0796
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0092 0.084 0.093
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0112 0.0078
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0504 0.5513 1
Schistosoma mansoni hypothetical protein 0.0052 0.0391 0.0645
Toxoplasma gondii proteasome subunit beta type, putative 0.0509 0.5566 1
Brugia malayi proteasome subunit alpha type 4 0.0092 0.084 0.093
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0134 0.132 0.129
Plasmodium vivax importin-beta 2, putative 0.0034 0.0191 0.0217
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0152 0.1526 0.1658
Echinococcus multilocularis proteasome subunit alpha type 6 0.0092 0.084 0.0808
Giardia lamblia Proteasome subunit beta type 3 0.0092 0.084 0.1456
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0347 0.373 0.668
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0092 0.084 0.1456
Plasmodium vivax proteasome subunit beta type-4, putative 0.0092 0.084 0.1398
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni lipoxygenase 0.0067 0.0557 0.0945
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0112 0.0078
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0491 0.0825
Brugia malayi ImpB/MucB/SamB family protein 0.0048 0.0341 0.0378
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0092 0.084 0.1456
Schistosoma mansoni nuclear hormone receptor 0.0238 0.2496 0.445
Schistosoma mansoni RAR-like nuclear receptor 0.0504 0.5513 0.9903
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0027 0.0112 0.0141
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0092 0.084 0.1398
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0052 0.0391 0.0433
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0236 0.0363
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0141
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0078
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0059 0.0475 0.049
Brugia malayi Steroid receptor seven-up type 2 0.0504 0.5513 0.6104
Schistosoma mansoni survival motor neuron protein 0.0053 0.0397 0.0655
Mycobacterium ulcerans proteasome PrcA 0.0092 0.084 0.1456
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0362 0.0401
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0217 0.2258 0.2472
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0504 0.5513 0.6104
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0393 0.425 0.762
Trypanosoma brucei proteasome beta 6 subunit 0.0347 0.373 0.4107
Brugia malayi follicle stimulating hormone receptor 0.0305 0.3257 0.3606
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0035 0.0038
Brugia malayi tailless protein 0.0238 0.2496 0.2764
Onchocerca volvulus 0.0027 0.0112 0.0074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0238 0.2496 0.247
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0092 0.084 0.0808
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0141
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0141
Brugia malayi Dopamine receptor protein 2 0.0027 0.0112 0.0125
Brugia malayi GnHR receptor homolog 0.0027 0.0112 0.0125
Onchocerca volvulus 0.0238 0.2496 0.4455
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Echinococcus granulosus muscleblind protein 0.0163 0.1643 0.1614
Schistosoma mansoni neuropeptide f receptor 76f 0.0027 0.0112 0.0141
Brugia malayi hypothetical protein 0.0024 0.0072 0.008
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0092 0.084 0.1398
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0238 0.2496 0.445
Mycobacterium ulcerans beta-lactamase 0.0038 0.0236 0.0363
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0048 0.0341 0.0378
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0147 0.0137
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0112 0.0078
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0112 0.0078
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0236 0.0363
Brugia malayi intermediate filament protein 0.0033 0.0171 0.019
Loa Loa (eye worm) hypothetical protein 0.0038 0.0236 0.0261
Leishmania major GTP-binding protein, putative 0.0025 0.0088 0.006
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0112 0.0078
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0027 0.0112 0.0141
Toxoplasma gondii peptidase, T1 family protein 0.0092 0.084 0.1372
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0236 0.0223
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0059 0.0475 0.0796
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0504 0.5513 0.9903
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0112 0.0141
Schistosoma mansoni nuclear receptor 0.0238 0.2496 0.445
Brugia malayi Melatonin receptor type 1A 0.0027 0.0112 0.0125
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0067 0.0557 0.0524
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0294 0.0375
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0112 0.0141
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0092 0.084 0.093
Schistosoma mansoni lamin 0.0033 0.0171 0.0247
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0134 0.132 0.1429
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0059 0.0475 0.0796
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0072 0.0038
Echinococcus granulosus g protein coupled receptor 0.0027 0.0112 0.0078
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0027 0.0112 0.0141
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0025 0.0088 0.0098
Brugia malayi nuclear receptor NHR-88 0.0238 0.2496 0.2764
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0059 0.0475 0.0796
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Giardia lamblia 20S proteasome alpha subunit 2 0.0092 0.084 0.1456
Echinococcus granulosus RUN 0.0024 0.0072 0.0038
Brugia malayi proteasome subunit alpha type 1 0.0092 0.084 0.093
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0393 0.425 0.423
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0059 0.0475 0.0796
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0347 0.373 0.3708
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0092 0.084 0.1456
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Schistosoma mansoni ran 0.0025 0.0088 0.0097
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0362 0.0591
Loa Loa (eye worm) hypothetical protein 0.0266 0.2819 0.3122
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0266 0.2819 0.5034
Echinococcus granulosus neuropeptide receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) cytochrome P450 family protein 0.0079 0.0697 0.0772
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0112 0.0078
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0159 0.0225
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0092 0.084 0.0895
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0141
Loa Loa (eye worm) PAS-3 protein 0.0092 0.084 0.093
Leishmania major importin beta-1 subunit, putative 0.0028 0.0118 0.0092
Loa Loa (eye worm) nuclear hormone receptor 0.0238 0.2496 0.2764
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0236 0.0363
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0141
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0092 0.084 0.1456
Echinococcus granulosus Nuclear hormone receptor HR96 0.0238 0.2496 0.247
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0141
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0509 0.5566 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0362 0.0328
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0112 0.0125
Echinococcus granulosus nuclear receptor nhr 48 0.0238 0.2496 0.247
Brugia malayi ORL1-like opioid receptor 0.0027 0.0112 0.0125
Trypanosoma cruzi Emopamil binding protein, putative 0.0152 0.1526 0.1658
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0092 0.084 0.0895
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0112 0.0078
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0347 0.373 0.3708
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0294 0.0469
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0112 0.0078
Mycobacterium ulcerans hypothetical protein 0.0038 0.0236 0.0363
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0112 0.0078
Mycobacterium ulcerans proteasome PrcB 0.0509 0.5566 1
Loa Loa (eye worm) PDE1B protein 0.0393 0.425 0.4705
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0072 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0092 0.084 0.1398
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0362 0.0364
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0092 0.084 0.1398
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0112 0.0078
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0362 0.0364
Brugia malayi Nuclear hormone receptor-like 1 0.0266 0.2819 0.3122
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0059 0.0475 0.0796
Schistosoma mansoni biogenic amine receptor 0.0027 0.0112 0.0141
Echinococcus multilocularis snurportin 1 0.0366 0.395 0.3929
Echinococcus granulosus proteasome subunit beta t family 0.0092 0.084 0.0808
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0092 0.084 0.1456
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0092 0.084 0.1372
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0112 0.0125
Schistosoma mansoni nuclear hormone receptor 0.0238 0.2496 0.445
Brugia malayi nuclear receptor RXR 0.0266 0.2819 0.3122
Mycobacterium leprae Conserved hypothetical protein 0.0059 0.0475 0.0449
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0191 0.0174
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0112 0.0078
Echinococcus granulosus proteasome prosome macropain 0.0509 0.5566 0.5551
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trypanosoma brucei protein kinase, putative 0.0049 0.0362 0.0364
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0217 0.2258 0.2231
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0027 0.0112 0.0074
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0092 0.084 0.1456
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Leishmania major proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0159 0.0125
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0025 0.0088 0.003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0238 0.2496 0.247
Echinococcus granulosus neuropeptide receptor A26 0.0027 0.0112 0.0078
Echinococcus granulosus subfamily T1A non peptidase ue 0.0092 0.084 0.0808
Onchocerca volvulus 0.0027 0.0112 0.0074
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0238 0.2496 0.445
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0504 0.5513 0.5497
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0305 0.3257 0.3606
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0509 0.5566 1
Brugia malayi Nuclear hormone receptor-like 1 0.0266 0.2819 0.3122
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.3333 0.3691
Leishmania major cytochrome p450-like protein 0.0059 0.0475 0.049
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0236 0.0363
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0092 0.084 0.093
Trypanosoma cruzi cytochrome P450, putative 0.0079 0.0697 0.0737
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0191 0.0174
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0217 0.2258 0.402
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0112 0.0078
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0059 0.0475 0.0796
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0112 0.0078
Brugia malayi photoreceptor-specific nuclear receptor 0.0504 0.5513 0.6104
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0059 0.0475 0.0796
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0092 0.084 0.093
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0362 0.0591
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0134 0.132 0.2272
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0092 0.084 0.1456
Brugia malayi hypothetical protein 0.003 0.0147 0.0163
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Echinococcus multilocularis neuropeptide s receptor 0.0027 0.0112 0.0078
Schistosoma mansoni biogenic amine receptor 0.0027 0.0112 0.0141
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0092 0.084 0.0808
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0236 0.0363
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0236 0.0223
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.2244 0.3994
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0067 0.0557 0.0524
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0504 0.5513 0.6104
Plasmodium vivax proteasome subunit beta type-6, putative 0.0092 0.084 0.1398
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0504 0.5513 0.9903
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0238 0.2496 0.247
Echinococcus multilocularis nuclear receptor nhr 48 0.0238 0.2496 0.247
Echinococcus multilocularis muscleblind protein 0.0163 0.1643 0.1614
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0092 0.084 0.0895
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0092 0.084 0.1456
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0147 0.0125
Brugia malayi Cytochrome P450 family protein 0.0059 0.0475 0.0526
Schistosoma mansoni hypothetical protein 0.0052 0.0391 0.0645
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0504 0.5513 0.9903
Giardia lamblia 20S proteasome alpha subunit 3 0.0092 0.084 0.1456
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0217 0.2258 0.3961
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0027
Trypanosoma brucei proteasome beta 7 subunit 0.0092 0.084 0.0895
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0236 0.0363
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0509 0.5566 0.6163
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0815 0.9031 1
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0059 0.0475 0.0796
Brugia malayi beta-lactamase 0.0038 0.0236 0.0261
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0347 0.373 0.4107
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0362 0.0364
Onchocerca volvulus 0.0152 0.1526 0.2673
Brugia malayi AKH receptor 0.0027 0.0112 0.0125
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0092 0.084 0.1456
Echinococcus granulosus dna polymerase eta 0.0048 0.0341 0.0308
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0266 0.2819 0.2794
Leishmania major proteasome alpha 1 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni hypothetical protein 0.0059 0.0475 0.0796
Onchocerca volvulus Notchless protein homolog 0.0092 0.084 0.1411
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0092 0.084 0.1372
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0152 0.1526 0.1658
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0092 0.084 0.1398
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0092 0.084 0.0895
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0236 0.0363
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0236 0.0363
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0092 0.084 0.5
Brugia malayi proteasome subunit alpha type 3 0.0092 0.084 0.093
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Toxoplasma gondii ABC1 family protein 0.0038 0.0236 0.0269
Schistosoma mansoni growth hormone secretagogue receptor 0.0027 0.0112 0.0141
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0504 0.5513 0.5497
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0112 0.0141
Brugia malayi Proteasome subunit alpha type 7-1 0.0092 0.084 0.093
Schistosoma mansoni hypothetical protein 0.0205 0.2119 0.3768
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0236 0.0363
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0112 0.0078
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0092 0.084 0.0895
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0509 0.5566 0.6148
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0052 0.0391 0.0358
Schistosoma mansoni polycystin 1-related 0.0024 0.0072 0.0068
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0059 0.0475 0.0796
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0504 0.5513 0.9903
Echinococcus granulosus neuropeptide receptor 0.0027 0.0112 0.0078
Brugia malayi proteasome subunit alpha type 6 0.0092 0.084 0.093
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0072 0.0038
Loa Loa (eye worm) hypothetical protein 0.0266 0.2819 0.3122
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0118 0.015
Brugia malayi RE15519p 0.0027 0.0112 0.0125
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0112 0.0125
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0059 0.0475 0.0796
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0901 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0504 0.5513 0.5497
Echinococcus granulosus intermediate filament protein 0.0033 0.0171 0.0137
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0491 0.0458
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0134 0.132 0.1429
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0347 0.373 0.668
Echinococcus granulosus proteasome subunit alpha type 6 0.0092 0.084 0.0808
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0134 0.132 0.129
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0092 0.084 0.1372
Schistosoma mansoni coup transcription factor 0.0504 0.5513 0.9903
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0147 0.0137
Brugia malayi cytochrome P450 0.0059 0.0475 0.0526
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0059 0.0475 0.0796
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0112 0.0125
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0112 0.0078
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0092 0.084 0.0895
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.2119 0.3762
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0059 0.0475 0.049
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Onchocerca volvulus 0.0504 0.5513 1
Onchocerca volvulus 0.0027 0.0112 0.0074
Brugia malayi G-protein coupled receptor 0.0027 0.0112 0.0125
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0059 0.0475 0.0796
Echinococcus multilocularis geminin 0.0205 0.2119 0.2092
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0147 0.0137
Echinococcus granulosus importin subunit beta 1 0.0034 0.0191 0.0157
Brugia malayi Pre-SET motif family protein 0.0031 0.0159 0.0176
Loa Loa (eye worm) hypothetical protein 0.0031 0.0159 0.0176
Schistosoma mansoni zinc finger protein 0.0238 0.2496 0.445
Schistosoma mansoni hypothetical protein 0.0205 0.2119 0.3768
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0112 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0504 0.5513 0.6104
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0092 0.084 0.1456
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0092 0.084 0.0895
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0397 0.0439
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0362 0.0364
Mycobacterium tuberculosis Conserved protein 0.0038 0.0236 0.0363
Schistosoma mansoni importin beta-1 0.0034 0.0191 0.0283
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0059 0.0475 0.0796
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0092 0.084 0.1134
Brugia malayi ecdysone receptor 0.0238 0.2496 0.2764
Brugia malayi Proteasome A-type and B-type family protein 0.0092 0.084 0.093
Plasmodium vivax SET domain protein, putative 0.0031 0.0159 0.0158
Trypanosoma brucei DNA polymerase eta, putative 0.0048 0.0341 0.0341
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0092 0.084 0.0895
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0092 0.084 0.1398
Echinococcus multilocularis musashi 0.0033 0.0171 0.0137
Plasmodium vivax proteasome subunit beta type-2, putative 0.0217 0.2258 0.3979
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0112 0.0141
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0052 0.0391 0.0358
Echinococcus granulosus somatostatin receptor 0.0027 0.0112 0.0078
Trypanosoma brucei cytochrome P450, putative 0.0079 0.0697 0.0737
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.008
Echinococcus multilocularis 0.0059 0.0475 0.0442
Onchocerca volvulus 0.0027 0.0112 0.0074
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.1474 0.1632
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0217 0.2258 0.2231
Toxoplasma gondii proteasome subunit alpha type, putative 0.0092 0.084 0.1372
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Schistosoma mansoni hypothetical protein 0.0024 0.0072 0.0068
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0092 0.084 0.1372
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.022 0.2287 0.2533
Schistosoma mansoni hypothetical protein 0.0052 0.0391 0.0645
Brugia malayi Serotonin receptor 0.0027 0.0112 0.0125
Brugia malayi ecdysteroid receptor 0.0504 0.5513 0.6104
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0815 0.9031 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0504 0.5513 0.6104
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0112 0.0125
Loa Loa (eye worm) beta-lactamase 0.0038 0.0236 0.0261
Schistosoma mansoni hypothetical protein 0.0112 0.1075 0.188
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0059 0.0475 0.0796
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0147 0.0107
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0112 0.0125
Onchocerca volvulus 0.0038 0.0236 0.0301
Brugia malayi proteasome subunit beta type 1 0.0347 0.373 0.413
Echinococcus granulosus snurportin 1 0.0366 0.395 0.3929
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0147 0.0125
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0092 0.084 0.1456
Loa Loa (eye worm) nuclear receptor NHR-67 0.0238 0.2496 0.2764
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Plasmodium falciparum importin beta, putative 0.0034 0.0191 0.0217
Brugia malayi Proteasome subunit alpha type 1 0.0092 0.084 0.093
Loa Loa (eye worm) latrophilin receptor protein 2 0.0052 0.0391 0.0433
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0092 0.084 0.1398
Onchocerca volvulus 0.0038 0.0236 0.0301
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0092 0.084 0.1456
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0504 0.5513 0.5497
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0092 0.084 0.0808
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0159 0.0129
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0092 0.084 0.1456
Echinococcus granulosus lamin 0.0033 0.0171 0.0137
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0141
Brugia malayi nuclear hormone receptor family member odr-7 0.0238 0.2496 0.2764
Echinococcus granulosus hypothetical protein 0.0027 0.0112 0.0078
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0025 0.0088 0.0098
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0238 0.2496 0.247
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0141
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0092 0.084 0.0895
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0059 0.0475 0.0796
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.1474 0.1445
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0092 0.084 0.1456
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0393 0.425 0.423
Echinococcus multilocularis ecdysone induced protein 78C 0.0504 0.5513 0.5497
Onchocerca volvulus Bile acid receptor homolog 0.0504 0.5513 1
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0141
Echinococcus granulosus FTZ F1 alpha 0.0504 0.5513 0.5497
Brugia malayi beta-lactamase family protein 0.0038 0.0236 0.0261
Onchocerca volvulus Neuropeptide F receptor homolog 0.0027 0.0112 0.0074
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0112 0.0078
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0134 0.132 0.1429
Echinococcus multilocularis serotonin receptor 0.0027 0.0112 0.0078
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0092 0.084 0.1456
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0092 0.084 0.1456
Plasmodium vivax proteasome subunit beta type-5, putative 0.0509 0.5566 1
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0059 0.0475 0.0796
Onchocerca volvulus 0.0027 0.0112 0.0074
Echinococcus granulosus Proteasome subunit alpha beta 0.0092 0.084 0.0808
Loa Loa (eye worm) acetyltransferase 0.0148 0.1474 0.1632
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0112 0.0125
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0112 0.0078
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0092 0.084 0.1398
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0092 0.084 0.0808
Echinococcus granulosus thyroid hormone receptor alpha 0.0238 0.2496 0.247
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Loa Loa (eye worm) hypothetical protein 0.0238 0.2496 0.2764
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0238 0.2496 0.4455
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0112 0.0078
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0266 0.2819 0.2794
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0504 0.5513 0.5497
Brugia malayi proteasome subunit beta type 3 0.0092 0.084 0.093
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0088 0.006
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0033 0.0181 0.0169
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0092 0.084 0.0895
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0118 0.0092
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.084 0.1456
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0092 0.084 0.1456
Leishmania major proteasome beta 7 subunit, putative 0.0092 0.084 0.0895
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0112 0.0078
Schistosoma mansoni ran 0.0025 0.0088 0.0097
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0504 0.5513 0.5497
Onchocerca volvulus 0.0027 0.0112 0.0074
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Echinococcus granulosus proteasome subunit alpha type 2 0.0092 0.084 0.0808
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0504 0.5513 0.9903
Onchocerca volvulus 0.0027 0.0112 0.0074
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0088 0.006
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0112 0.0078
Loa Loa (eye worm) proteasome subunit beta type 2 0.0217 0.2258 0.2501
Loa Loa (eye worm) hypothetical protein 0.0052 0.0391 0.0433
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0112 0.0125
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0181 0.0163
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni hypothetical protein 0.0052 0.0391 0.0645
Mycobacterium leprae putative cytochrome p450 0.0059 0.0475 0.0449
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0509 0.5566 1
Mycobacterium tuberculosis Conserved protein 0.0038 0.0236 0.0363
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3333 0.5963
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0362 0.0591
Schistosoma mansoni lamin 0.0033 0.0171 0.0247
Onchocerca volvulus 0.0038 0.0236 0.0301
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0238 0.2496 0.247
Echinococcus granulosus fmrfamide receptor 0.0027 0.0112 0.0078
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0491 0.0735
Echinococcus granulosus g protein coupled receptor 0.0027 0.0112 0.0078
Plasmodium vivax proteasome subunit beta type-3, putative 0.0092 0.084 0.1398
Schistosoma mansoni opsin-like receptor 0.0027 0.0112 0.0141
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0253 0.033
Loa Loa (eye worm) hypothetical protein 0.0504 0.5513 0.6104
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0059 0.0475 0.0796
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0509 0.5566 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0238 0.2496 0.2764
Loa Loa (eye worm) proteasome subunit beta type 1 0.0347 0.373 0.413
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0027 0.0112 0.0141
Brugia malayi hypothetical protein 0.0027 0.0112 0.0125
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0092 0.084 0.0808
Onchocerca volvulus 0.0027 0.0112 0.0074
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni lipoxygenase 0.0024 0.0072 0.0068
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0092 0.084 0.0808
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0035 0.0038
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0504 0.5513 0.5497
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0092 0.084 0.1456
Schistosoma mansoni cytochrome P450 0.0059 0.0475 0.0796
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0059 0.0475 0.0796
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0078
Echinococcus granulosus Proteasome subunit alpha type 7 0.0092 0.084 0.0808
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0078
Plasmodium falciparum proteasome subunit beta type-4 0.0092 0.084 0.1398
Mycobacterium ulcerans lipase LipD 0.0038 0.0236 0.0363
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0134 0.132 0.1429
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0027 0.0112 0.0078
Echinococcus multilocularis dna polymerase eta 0.0048 0.0341 0.0308
Brugia malayi nuclear receptor NHR-67 0.0238 0.2496 0.2764
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0092 0.084 0.1372
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0164 0.1664 0.1842
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0238 0.2496 0.2764
Loa Loa (eye worm) hypothetical protein 0.0266 0.2819 0.3122
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0092 0.084 0.0895
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0236 0.0298
Schistosoma mansoni rab6-interacting 0.0024 0.0072 0.0068
Giardia lamblia 20S proteasome alpha subunit 6 0.0092 0.084 0.1456
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0362 0.0591
Schistosoma mansoni histamine h1 receptor 0.0027 0.0112 0.0141
Brugia malayi Doublecortin family protein 0.0024 0.0072 0.008
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0236 0.0261
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0118 0.015
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0092 0.084 0.0895
Schistosoma mansoni alpha-1 adrenergic receptor 0.0027 0.0112 0.0141
Toxoplasma gondii proteasome subunit 0.0092 0.084 0.1372
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0504 0.5513 0.5497
Onchocerca volvulus 0.0027 0.0112 0.0074
Schistosoma mansoni loxhd1 0.0024 0.0072 0.0068
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0125
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0491 0.0825
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0141
Brugia malayi Proteasome A-type and B-type family protein 0.0092 0.084 0.093
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0504 0.5513 0.5497

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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