Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.6738 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.3447 | 0.3447 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1262 | 0.1702 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0042 | 0.207 | 0.207 |
Echinococcus granulosus | peregrin | 0.0038 | 0.1574 | 0.1574 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0072 | 0.5351 | 0.7899 |
Schistosoma mansoni | bromodomain containing protein | 0.0076 | 0.5757 | 0.7765 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0071 | 0.5286 | 0.5286 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.191 | 0.2577 |
Brugia malayi | Bromodomain containing protein | 0.009 | 0.7301 | 0.7097 |
Giardia lamblia | PHD finger protein 15 | 0.0035 | 0.1262 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0071 | 0.5286 | 0.5286 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0114 | 1 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.0035 | 0.1262 | 0.5 |
Onchocerca volvulus | Alhambra homolog | 0.0035 | 0.1262 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0035 | 0.1262 | 0.1701 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.3447 | 0.3447 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0044 | 0.2321 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.3988 | 0.5833 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.006 | 0.3988 | 0.5833 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0048 | 0.2766 | 0.2766 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.006 | 0.3988 | 0.3534 |
Brugia malayi | Bromodomain containing protein | 0.0046 | 0.2466 | 0.1897 |
Schistosoma mansoni | jumonji domain containing protein | 0.0091 | 0.7415 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0035 | 0.1262 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.1574 | 0.0937 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.4006 | 0.5859 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0035 | 0.1262 | 0.1262 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0139 | 0.0188 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0044 | 0.2321 | 0.2321 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0035 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.2476 | 0.3541 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0027 | 0.0391 | 0.0527 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.3447 | 0.3447 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.3447 | 0.4649 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0027 | 0.0391 | 0.0391 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0043 | 0.2155 | 0.2155 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0055 | 0.3447 | 0.5013 |
Brugia malayi | PHD-finger family protein | 0.0035 | 0.1262 | 0.0601 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0035 | 0.1262 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.3447 | 0.4649 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2788 | 0.4014 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.3447 | 0.3447 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0114 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.3447 | 0.4649 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1262 | 0.1701 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.191 | 0.2684 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0027 | 0.0391 | 0.0391 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0043 | 0.2155 | 0.2155 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0041 | 0.191 | 0.1299 |
Echinococcus granulosus | jumonji domain containing protein | 0.0048 | 0.2766 | 0.2766 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0035 | 0.1262 | 0.1702 |
Echinococcus multilocularis | peregrin | 0.0038 | 0.1574 | 0.1574 |
Brugia malayi | jmjC domain containing protein | 0.0044 | 0.2321 | 0.1741 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0044 | 0.2321 | 0.3307 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.006 | 0.3988 | 0.3534 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0044 | 0.2321 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.3039 | 0.4395 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.1262 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0055 | 0.3447 | 0.2952 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.