Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0051 | 0.3849 | 0.3849 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.3849 | 0.5 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0051 | 0.3849 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0051 | 0.3849 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0051 | 0.3849 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.3849 | 0.5 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0051 | 0.3849 | 0.5 |
Trypanosoma brucei | protein kinase, putative | 0.0051 | 0.3849 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.2503 | 0.6502 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.3849 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0051 | 0.3849 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0051 | 0.3849 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0121 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.3849 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0051 | 0.3849 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.2503 | 0.6502 |
Brugia malayi | MAP kinase sur-1 | 0.0051 | 0.3849 | 0.3849 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.2503 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0121 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.2503 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.2503 | 0.6502 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0051 | 0.3849 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.3849 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0051 | 0.3849 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.2503 | 0.6502 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0051 | 0.3849 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.2503 | 0.5 |
Brugia malayi | hypothetical protein | 0.0036 | 0.2503 | 0.2503 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0051 | 0.3849 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0051 | 0.3849 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.3849 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.2503 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.