Detailed information for compound 577529

Basic information

Technical information
  • TDR Targets ID: 577529
  • Name: N-ethyl-4-methyl-benzenesulfonamide
  • MW: 199.27 | Formula: C9H13NO2S
  • H donors: 1 H acceptors: 2 LogP: 1.62 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCNS(=O)(=O)c1ccc(cc1)C
  • InChi: 1S/C9H13NO2S/c1-3-10-13(11,12)9-6-4-8(2)5-7-9/h4-7,10H,3H2,1-2H3
  • InChiKey: OHPZPBNDOVQJMH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-ethyl-4-methylbenzenesulfonamide
  • N-ethyl-4-toluenesulfonamide
  • 80-39-7
  • 825629-31-0
  • 8047-99-2
  • CCRIS 6037
  • EINECS 201-275-1
  • Ethyl tosylamide
  • N-Ethyl-4-methyl benzenesulfonamide
  • N-Ethyltoluene-4-sulphonamide
  • NSC 68803
  • p-Toluenesulfonamide, N-ethyl- (8CI)
  • NCIOpen2_000527
  • AI3-04487
  • AI3-08014
  • Benzenesulfonamide, N-ethyl-2(or 4)-methyl-
  • CCRIS 6102
  • EINECS 232-465-2
  • Ketjenflex 8
  • N-Ethyl-2(or 4)-methylbenzenesulfonamide
  • N-Ethyl-o(or p)-toluenesulphonamide
  • N-Ethyltoluenesulfonamide
  • Santicizer 8
  • TOLUENE ETHYLSULFONAMIDE
  • ZINC00134748
  • NCGC00091206-01
  • Benzenesulfonamide, N-ethyl-4-methyl-
  • N-Ethyl-p-methylbenzenesulfonamide
  • N-Ethyl-p-toluenesulfonamide
  • N-Ethyl-p-tolylsulfonamide
  • N-Tosylethylamine
  • NSC68803
  • Santicizer 3
  • p-Tolueneethylsulfonamide
  • p-Toluenesulfonamide, N-ethyl-
  • p-Toluenesulfonyl-N-ethylamide
  • BTB 12698
  • 415367_ALDRICH

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus g protein coupled receptor 0.0019 0.2623 0.1879
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.2623 0.2623
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus multilocularis serotonin receptor 0.0019 0.2623 0.1879
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.2623 0.1879
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Echinococcus multilocularis g protein coupled receptor 0.0019 0.2623 0.1879
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.2623 0.2623
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.2623 0.1879
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.2623 0.2623
Echinococcus multilocularis neuropeptide receptor 0.0019 0.2623 0.1879
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.2623 0.2623
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.2623 0.2543
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.2623 0.1508
Loa Loa (eye worm) intermediate filament protein 0.0027 0.4788 0.4732
Echinococcus granulosus lamin 0.0027 0.4788 0.4263
Brugia malayi neuropeptide F receptor 0.0019 0.2623 0.1508
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.2623 0.1879
Brugia malayi Dopamine receptor protein 1 0.0019 0.2623 0.1508
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.2623 0.2623
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.2623 0.1879
Brugia malayi ORL1-like opioid receptor 0.0019 0.2623 0.1508
Schistosoma mansoni amine GPCR 0.0019 0.2623 0.2623
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 1 1
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.2804 0.5
Schistosoma mansoni hypothetical protein 0.0019 0.2623 0.2623
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.2623 0.1879
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.2623 0.1879
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.2623 0.2623
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.2623 0.2623
Schistosoma mansoni hypothetical protein 0.0019 0.2623 0.2623
Brugia malayi hypothetical protein 0.0019 0.2623 0.1508
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.2623 0.1879
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.2623 0.1879
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.2804 0.5
Echinococcus multilocularis fmrfamide receptor 0.0019 0.2623 0.1879
Brugia malayi Serotonin receptor 0.0019 0.2623 0.1508
Echinococcus multilocularis g protein coupled receptor 0.0019 0.2623 0.1879
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.2623 0.1879
Brugia malayi hypothetical protein 0.0019 0.2623 0.1508
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.2623 0.1879
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 1 1
Echinococcus multilocularis neuropeptide receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.2623 0.2623
Schistosoma mansoni intermediate filament proteins 0.0027 0.4788 0.4788
Brugia malayi intermediate filament protein 0.0027 0.4788 0.4001
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.2623 0.2543
Brugia malayi G-protein coupled receptor 0.0019 0.2623 0.1508
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.2623 0.1508
Brugia malayi G protein-coupled receptor 0.0019 0.2623 0.1508
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0026 0.4652 0.4594
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.2623 0.1508
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.4788 0.4732
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.2623 0.2623
Schistosoma mansoni opsin-like receptor 0.0019 0.2623 0.2623
Echinococcus granulosus intermediate filament protein 0.0027 0.4788 0.4263
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 1 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.2623 0.2543
Brugia malayi AKH receptor 0.0019 0.2623 0.1508
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.2623 0.1508
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.2623 0.1508
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Schistosoma mansoni hypothetical protein 0.0019 0.2623 0.2623
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.2623 0.2623
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.2623 0.1879
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.2623 0.2543
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.2623 0.1879
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0107 0.0107
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.2804 0.2079
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.2623 0.1879
Schistosoma mansoni lamin 0.0027 0.4788 0.4788
Brugia malayi Melatonin receptor type 1A 0.0019 0.2623 0.1508
Schistosoma mansoni DNA helicase recq5 0.002 0.2804 0.2804
Schistosoma mansoni neuropeptide receptor 0.0019 0.2623 0.2623
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Schistosoma mansoni histamine h1 receptor 0.0019 0.2623 0.2623
Brugia malayi neuropeptide F receptor 0.0019 0.2623 0.1508
Entamoeba histolytica recQ family helicase, putative 0.002 0.2804 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.2623 0.1879
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Echinococcus granulosus bloom syndrome protein 0.002 0.2804 0.2079
Schistosoma mansoni DNA helicase recq1 0.002 0.2804 0.2804
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Onchocerca volvulus 0.0027 0.4788 1
Echinococcus granulosus neuropeptide s receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Brugia malayi putative neuropeptide receptor 0.0019 0.2623 0.1508
Loa Loa (eye worm) hypothetical protein 0.0012 0.0778 0.0679
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.2623 0.2623
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Schistosoma mansoni adenoreceptor 0.0019 0.2623 0.2623
Brugia malayi larval opioid receptor 0.0019 0.2623 0.1508
Brugia malayi Dopamine receptor protein 2 0.0019 0.2623 0.1508
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.2623 0.2543
Echinococcus multilocularis serotonin receptor 0.0019 0.2623 0.1879
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Brugia malayi GnHR receptor homolog 0.0019 0.2623 0.1508
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.2623 0.1508
Schistosoma mansoni biogenic amine receptor 0.0019 0.2623 0.2623
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.2804 0.5
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.2623 0.2623
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.2623 0.2543
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Echinococcus multilocularis lamin 0.0027 0.4788 0.4263
Echinococcus multilocularis orexin receptor type 2 0.0019 0.2623 0.1879
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.2623 0.1879
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.2623 0.1879
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.2623 0.2623
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.2623 0.1508
Echinococcus multilocularis fmrfamide receptor 0.0019 0.2623 0.1879
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.2804 0.5
Echinococcus multilocularis bloom syndrome protein 0.002 0.2804 0.2079
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.2804 0.5
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Schistosoma mansoni opsin-like receptor 0.0019 0.2623 0.2623
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.2804 0.2079
Echinococcus granulosus neuropeptide receptor 0.0019 0.2623 0.1879
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0013 0.0915 0.0817
Brugia malayi hypothetical protein 0.0019 0.2623 0.1508
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.2623 0.2623
Schistosoma mansoni lamin 0.0027 0.4788 0.4788
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.2623 0.2543
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Schistosoma mansoni amine GPCR 0.0019 0.2623 0.2623
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.2623 0.1879
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.2804 0.2079
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.2804 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.2623 0.2543
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.0107 1
Echinococcus granulosus neuropeptide receptor A26 0.0019 0.2623 0.1879
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.2623 0.2623
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.2623 0.1879
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.2623 0.1879
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.2623 0.1879
Echinococcus multilocularis sex peptide receptor 0.0019 0.2623 0.1879
Brugia malayi hypothetical protein 0.0019 0.2623 0.1508
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.2623 0.2543
Echinococcus multilocularis lamin dm0 0.0027 0.4788 0.4263
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.2623 0.2543
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.2804 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0107 0.000000002293
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.2623 0.2623
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus granulosus serotonin receptor 0.0019 0.2623 0.1879
Treponema pallidum ATP-dependent DNA helicase 0.001 0.0107 0.5
Schistosoma mansoni neuropeptide receptor 0.0019 0.2623 0.2623
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 1 1
Schistosoma mansoni neuropeptide receptor 0.0019 0.2623 0.2623
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.2623 0.1879
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.2623 0.1879
Echinococcus granulosus allatostatin A receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Entamoeba histolytica recQ family DNA helicase 0.001 0.0107 0.0381
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus granulosus orexin receptor type 2 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.2623 0.2623
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.2623 0.1879
Brugia malayi hypothetical protein 0.0019 0.2623 0.1508
Echinococcus granulosus sex peptide receptor 0.0019 0.2623 0.1879
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.2623 0.2623
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.2804 0.5
Echinococcus multilocularis musashi 0.0027 0.4788 0.4263
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0107 0.0381
Brugia malayi G-protein coupled receptor 0.0019 0.2623 0.1508
Brugia malayi RE15519p 0.0019 0.2623 0.1508
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.2623 0.2623
Brugia malayi Dopamine receptor 0.0019 0.2623 0.1508
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0012 0.0778 0.0679
Brugia malayi Bloom's syndrome protein homolog 0.002 0.2804 0.1717
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.2623 0.1879
Brugia malayi hypothetical protein 0.0019 0.2623 0.1508
Schistosoma mansoni biogenic amine receptor 0.0019 0.2623 0.2623
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.2804 0.2079
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.2623 0.1879
Schistosoma mansoni amine GPCR 0.0019 0.2623 0.2623
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.2623 0.1879
Echinococcus granulosus g protein coupled receptor 0.0019 0.2623 0.1879
Brugia malayi follicle stimulating hormone receptor 0.0019 0.2623 0.1508
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.2623 0.2623
Echinococcus granulosus fmrfamide receptor 0.0019 0.2623 0.1879
Schistosoma mansoni neuropeptide receptor 0.0019 0.2623 0.2623
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.2623 0.1879
Onchocerca volvulus 0.0027 0.4788 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 1 1
Schistosoma mansoni myosin xvIII 0.0019 0.2623 0.2623
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.2804 0.5
Brugia malayi Serotonin receptor 0.0019 0.2623 0.1508
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus granulosus lamin dm0 0.0027 0.4788 0.4263
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.2623 0.2623
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Brugia malayi hypothetical protein 0.0019 0.2623 0.1508
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.2623 0.1879
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.2623 0.2623
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.2623 0.1879
Echinococcus granulosus g-protein coupled receptor 0.0019 0.2623 0.1879
Echinococcus granulosus neuropeptide receptor 0.0019 0.2623 0.1879
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.2804 0.1717
Echinococcus granulosus g protein coupled receptor 0.0019 0.2623 0.1879
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.2623 0.2623
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus multilocularis allatostatin A receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.2623 0.2623
Loa Loa (eye worm) RecQ helicase 0.002 0.2804 0.2726
Brugia malayi hypothetical protein 0.0019 0.2623 0.1508
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.2623 0.1879
Schistosoma mansoni biogenic amine receptor 0.0019 0.2623 0.2623
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.2623 0.1879
Echinococcus multilocularis neuropeptide s receptor 0.0019 0.2623 0.1879
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.2623 0.2623
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.2623 0.2623
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.2623 0.2623
Brugia malayi hypothetical protein 0.0019 0.2623 0.1508
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.2804 1
Echinococcus multilocularis neuropeptide receptor A26 0.0019 0.2623 0.1879
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.2623 0.2623
Echinococcus multilocularis somatostatin receptor 0.0019 0.2623 0.1879
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.4788 0.4001
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.2623 0.1879
Echinococcus granulosus somatostatin receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Brugia malayi sulfakinin receptor protein 0.0019 0.2623 0.1508
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 1 1
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.2623 0.2543
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.2623 0.2623
Schistosoma mansoni amine GPCR 0.0019 0.2623 0.2623
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.2623 0.1879
Echinococcus granulosus hypothetical protein 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Loa Loa (eye worm) hypothetical protein 0.002 0.2804 0.2726
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.1313 0.1219
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.2623 0.1508
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.2804 0.1717
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Schistosoma mansoni amine GPCR 0.0019 0.2623 0.2623
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.2623 0.1879
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Schistosoma mansoni hypothetical protein 0.0019 0.2623 0.2623
Schistosoma mansoni opsin-like receptor 0.0019 0.2623 0.2623
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0027 0.4788 0.4732
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.2804 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.2623 0.1879
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.2804 0.2726
Brugia malayi hypothetical protein 0.0019 0.2623 0.1508
Echinococcus multilocularis g protein coupled receptor 0.0019 0.2623 0.1879
Loa Loa (eye worm) hypothetical protein 0.0019 0.2623 0.2543

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: Cell Viability - LYMP2-006. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.