Detailed information for compound 577807

Basic information

Technical information
  • TDR Targets ID: 577807
  • Name: (2R,4R)-2-hydroxy-4-[(3R,5S,7R,8R,9S,10S,12S, 13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl -2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecah ydro-1H-cyclopenta[a]phenanthren-17-yl]pentan oic acid
  • MW: 424.571 | Formula: C24H40O6
  • H donors: 5 H acceptors: 6 LogP: 3.02 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@@H]1CC[C@]2([C@@H](C1)C[C@H]([C@@H]1[C@@H]2C[C@H](O)[C@]2([C@H]1CC[C@@H]2[C@@H](C[C@H](C(=O)O)O)C)C)O)C
  • InChi: 1S/C24H40O6/c1-12(8-19(27)22(29)30)15-4-5-16-21-17(11-20(28)24(15,16)3)23(2)7-6-14(25)9-13(23)10-18(21)26/h12-21,25-28H,4-11H2,1-3H3,(H,29,30)/t12-,13+,14-,15-,16+,17+,18-,19-,20+,21+,23+,24-/m1/s1
  • InChiKey: UJYLRDMHTJWIQW-SWSYAYITSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (2R,4R)-2-hydroxy-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]valeric acid
  • 3,7,12,23-tetrahydroxycholan-24-oic acid
  • 6879-45-4
  • (23R)-3alpha,7alpha,12alpha,23-Tetrahydroxy-5beta-cholan-24-oic Acid
  • LMST04010254
  • 3,7,12,23-TCOA
  • 3alpha,7alpha,12alpha,23-Tetrahydroxy-5beta-cholan-24-oic acid
  • Cholan-24-oic acid, 3,7,12,23-tetrahydroxy-, (3alpha,5beta,7alpha,12alpha,23R)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0443 0.056
Entamoeba histolytica hypothetical protein 0.0073 0.0306 0.0387
Echinococcus granulosus FTZ F1 alpha 0.0024 0.0000060164 0.0000076111
Brugia malayi Variant SH3 domain containing protein 0.0043 0.0121 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0211 0.0267
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0092 0.0426 0.0538
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0336 0.194 0.1914
Entamoeba histolytica hypothetical protein 0.0043 0.0121 0.0153
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0043 0.0121 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0024 0.0000060164 0.0000076111
Echinococcus multilocularis protein patched 0.0042 0.0113 0.0143
Loa Loa (eye worm) hypothetical protein 0.0073 0.0307 0.0388
Echinococcus multilocularis pyruvate kinase 0.0034 0.0061 0.0077
Loa Loa (eye worm) hypothetical protein 0.0088 0.0402 0.0509
Loa Loa (eye worm) hypothetical protein 0.003 0.0038 0.0048
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0092 0.0426 0.0426
Brugia malayi RhoGAP domain containing protein 0.0044 0.0128 0.0162
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0092 0.0426 0.0426
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0113 0.0143
Loa Loa (eye worm) SH2 domain-containing protein 0.0044 0.0128 0.0162
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0307 0.0275
Onchocerca volvulus 0.0044 0.0128 0.0181
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0307 0.0307
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0057 0.0205 0.026
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.1295 0.7905 1
Echinococcus granulosus tensin 0.0044 0.0128 0.0162
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.1295 0.7905 1
Echinococcus multilocularis c src tyrosine kinase 0.01 0.0475 0.06
Echinococcus multilocularis tyrosine protein kinase shark 0.0057 0.0205 0.026
Entamoeba histolytica BAR/SH3 domain containing protein 0.0043 0.0121 0.0153
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.072 0.0911
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0073 0.0092
Echinococcus granulosus expressed protein 0.0043 0.0121 0.0153
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.1295 0.7905 1
Echinococcus multilocularis pyruvate kinase 0.0034 0.0061 0.0077
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.055 0.0695
Schistosoma mansoni kinase 0.0059 0.0217 0.0275
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0959 0.5817 0.7359
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0618 0.0782
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0092 0.0426 0.0538
Entamoeba histolytica hypothetical protein, conserved 0.0043 0.0121 0.0153
Loa Loa (eye worm) dihydrofolate reductase 0.0473 0.2791 0.3531
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0024 0.0000060164 0.0000076111
Loa Loa (eye worm) SH2 domain-containing protein 0.0044 0.0128 0.0162
Schistosoma mansoni hypothetical protein 0.0043 0.0121 0.0153
Echinococcus multilocularis survival motor neuron protein 1 0.0272 0.1543 0.1951
Loa Loa (eye worm) hypothetical protein 0.0043 0.0121 0.0153
Loa Loa (eye worm) TK/FER protein kinase 0.0057 0.0205 0.026
Schistosoma mansoni signal transduction protein lnk-related 0.0044 0.0128 0.0162
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0307 0.0388
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0467 0.2757 0.3672
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0044 0.0128 0.0162
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0336 0.194 0.2454
Trichomonas vaginalis chromobox protein, putative 0.0088 0.0398 0.0503
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0154 0.0195
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0113 0.0143
Leishmania major hypothetical protein, conserved 0.0073 0.0307 0.0275
Loa Loa (eye worm) SRC-1 0.01 0.0475 0.06
Brugia malayi Pre-SET motif family protein 0.0205 0.1128 0.1427
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.004 0.0051
Schistosoma mansoni alpha-glucosidase 0.0138 0.0708 0.0895
Loa Loa (eye worm) STAT protein 0.0044 0.0128 0.0162
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0044 0.0128 0.0162
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.01 0.0475 0.06
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0000000076446 0.0000000096709
Brugia malayi Variant SH3 domain containing protein 0.0043 0.0121 0.0153
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0473 0.2791 0.3723
Echinococcus multilocularis SH2 motif 0.0044 0.0128 0.0162
Schistosoma mansoni pyruvate kinase 0.0066 0.0259 0.0328
Echinococcus granulosus expressed conserved protein 0.0092 0.0423 0.0535
Onchocerca volvulus 0.0028 0.0029 0.0041
Onchocerca volvulus 0.0054 0.0186 0.0264
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.046 0.0581
Echinococcus multilocularis expressed protein 0.0043 0.0121 0.0153
Loa Loa (eye worm) latrophilin receptor protein 2 0.0101 0.0481 0.0609
Echinococcus granulosus mitogen activated protein kinase 14 0.0983 0.5967 0.7548
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0121 0.0089
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0044 0.0128 0.0162
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.001 0.0013
Brugia malayi ecdysteroid receptor 0.0024 0.0000060164 0.0000076111
Mycobacterium leprae Probable lipase LipE 0.0073 0.0307 0.0069
Mycobacterium tuberculosis Conserved protein 0.0073 0.0307 0.0069
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0259 0.0367
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0028 0.0035
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0073 0.0041
Brugia malayi SH2 domain containing protein 0.0044 0.0128 0.0162
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0846 0.1071
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0307 0.0275
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0044 0.0128 0.0162
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0307 0.0069
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0983 0.5967 0.5954
Brugia malayi chromobox protein homolog 3 0.0082 0.0359 0.0454
Loa Loa (eye worm) TK/FER protein kinase 0.0057 0.0205 0.026
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0073 0.0041
Loa Loa (eye worm) TK/FER protein kinase 0.0057 0.0205 0.026
Schistosoma mansoni hypothetical protein 0.0055 0.0197 0.0249
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0306 0.0387
Brugia malayi SH2 domain containing protein 0.0044 0.0128 0.0162
Echinococcus granulosus hypothetical protein 0.0044 0.0128 0.0162
Loa Loa (eye worm) hypothetical protein 0.0043 0.0121 0.0153
Onchocerca volvulus 0.0064 0.025 0.0353
Trypanosoma cruzi hypothetical protein, conserved 0.0336 0.194 0.1914
Echinococcus granulosus tyrosine protein kinase Src42A 0.01 0.0475 0.06
Onchocerca volvulus 0.0044 0.0128 0.0181
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.1632 1 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Loa Loa (eye worm) hypothetical protein 0.0043 0.0121 0.0153
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0607 0.3629 0.459
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0473 0.2791 0.3723
Giardia lamblia Pyruvate kinase 0.0066 0.0259 0.0253
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0024 0.0000060164 0.0000076111
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0024 0.0000060164 0.0000076111
Loa Loa (eye worm) beta-lactamase 0.0073 0.0307 0.0388
Echinococcus granulosus intersectin 2 0.0043 0.0121 0.0153
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0336 0.194 0.1914
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0024 0.0000060164 0.0000076111
Loa Loa (eye worm) hypothetical protein 0.0073 0.0307 0.0388
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.1295 0.7905 1
Schistosoma mansoni coup transcription factor 0.0024 0.0000060164 0.0000076111
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0073 0.0041
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0307 0.0069
Echinococcus granulosus pyruvate kinase 0.0066 0.0259 0.0328
Echinococcus granulosus SH2 motif 0.0044 0.0128 0.0162
Echinococcus multilocularis cpg binding protein 0.003 0.0039 0.005
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0038 0.0048
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0044 0.0128 0.0162
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0043 0.0121 0.0153
Schistosoma mansoni growth factor receptor-bound protein 0.0088 0.0397 0.0502
Loa Loa (eye worm) steroid hormone receptor 0.0024 0.0000060164 0.0000076111
Echinococcus granulosus Chromobox protein 3 0.0024 0.0000000076446 0.0000000096709
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0000060164 0.0000076111
Loa Loa (eye worm) TK/FER protein kinase 0.0057 0.0205 0.026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0443 0.056
Echinococcus granulosus ecdysone induced protein 78C 0.0024 0.0000060164 0.0000076111
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0073 0.0073
Brugia malayi hypothetical protein 0.0044 0.0128 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0121 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0211 0.0267
Echinococcus multilocularis tyrosine protein kinase Fyn 0.01 0.0475 0.06
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0000060164 0.0000076111
Brugia malayi photoreceptor-specific nuclear receptor 0.0024 0.0000060164 0.0000076111
Echinococcus granulosus thymidylate synthase 0.1159 0.7061 0.8932
Schistosoma mansoni dreadlocks/dock 0.0043 0.0121 0.0153
Entamoeba histolytica hypothetical protein 0.0043 0.0121 0.0153
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0846 0.1071
Brugia malayi SH2 domain containing protein 0.0044 0.0128 0.0162
Schistosoma mansoni growth factor receptor-bound protein 0.0088 0.0397 0.0502
Loa Loa (eye worm) TK/ABL protein kinase 0.0057 0.0205 0.026
Brugia malayi Dihydrofolate reductase 0.0473 0.2791 0.3531
Loa Loa (eye worm) hypothetical protein 0.0024 0.0000060164 0.0000076111
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.0041
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0259 0.0228
Loa Loa (eye worm) hypothetical protein 0.0024 0.0000060164 0.0000076111
Brugia malayi STAT protein, DNA binding domain containing protein 0.0044 0.0128 0.0162
Echinococcus multilocularis dihydrofolate reductase 0.0473 0.2791 0.3531
Toxoplasma gondii ABC1 family protein 0.0073 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.1295 0.7905 1
Brugia malayi tRNA modification GTPase TrmE family protein 0.0044 0.0128 0.0162
Loa Loa (eye worm) hypothetical protein 0.0057 0.0205 0.026
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0029 0.0037
Echinococcus multilocularis tyrosine protein kinase Src42A 0.01 0.0475 0.06
Echinococcus granulosus tyrosine protein kinase ABL1 0.0057 0.0205 0.026
Echinococcus granulosus Spectrin alpha actinin 0.0043 0.0121 0.0153
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0024 0.0000060164 0.0000076111
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0073 0.0092
Plasmodium falciparum geranylgeranyltransferase, putative 0.0092 0.0426 0.0426
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0101 0.0481 0.0609
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0073 0.0092
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0043 0.0121 0.0153
Brugia malayi Protein kinase domain containing protein 0.0057 0.0205 0.026
Schistosoma mansoni adapter molecule crk 0.0088 0.0397 0.0502
Brugia malayi Spectrin alpha chain 0.0043 0.0121 0.0153
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.01 0.0475 0.06
Echinococcus granulosus chromobox protein 1 0.0145 0.0757 0.0957
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0121 0.0153
Echinococcus multilocularis tyrosine protein kinase Fyn 0.01 0.0475 0.06
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0044 0.0128 0.0162
Brugia malayi hypothetical protein 0.0272 0.1543 0.1951
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0121 0.0153
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0092 0.0426 0.0426
Onchocerca volvulus 0.0057 0.0205 0.0291
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0336 0.194 0.1914
Echinococcus multilocularis pyruvate kinase 0.0034 0.0061 0.0077
Brugia malayi latrophilin 2 splice variant baaae 0.0219 0.1212 0.1533
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0113 0.0143
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni chromobox protein 0.0145 0.0757 0.0957
Schistosoma mansoni tensin 0.0044 0.0128 0.0162
Toxoplasma gondii hypothetical protein 0.0336 0.194 0.194
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0044 0.0128 0.0162
Echinococcus granulosus growth factor receptor bound protein 2 0.0088 0.0397 0.0502
Brugia malayi Protein kinase domain containing protein 0.0057 0.0205 0.026
Entamoeba histolytica hypothetical protein 0.0043 0.0121 0.0153
Brugia malayi hypothetical protein 0.0551 0.3281 0.4151
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.055 0.0695
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0073 0.0092
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.055 0.0695
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0336 0.194 0.1914
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni tyrosine kinase 0.0057 0.0205 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0121 0.0153
Onchocerca volvulus Protein ultraspiracle homolog 0.0024 0.0000060164 0.0000085212
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.1295 0.7905 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Mycobacterium ulcerans thymidylate synthase 0.1159 0.7061 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0112 0.055 0.0695
Echinococcus granulosus SHC transforming protein 3 0.0044 0.0128 0.0162
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0336 0.194 0.1914
Giardia lamblia Rab geranylgeranyltransferase 0.1295 0.7905 1
Onchocerca volvulus Bile acid receptor homolog 0.0024 0.0000060164 0.0000085212
Loa Loa (eye worm) CHromoDomain protein family member 0.0025 0.001 0.0013
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0032 0.0032
Schistosoma mansoni tyrosine kinase 0.01 0.0475 0.06
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0607 0.3629 0.459
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.1295 0.7905 1
Trypanosoma brucei glucosidase, putative 0.0035 0.0073 0.0041
Schistosoma mansoni hypothetical protein 0.0101 0.0481 0.0609
Brugia malayi SH2 domain containing protein 0.0057 0.0205 0.026
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0073 0.0092
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0032 0.0032
Echinococcus granulosus tumor protein p63 0.0332 0.1918 0.2426
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0022 0.0027
Echinococcus granulosus src region 0.0043 0.0121 0.0153
Echinococcus granulosus pyruvate kinase 0.0034 0.0061 0.0077
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0057 0.0205 0.026
Entamoeba histolytica serine/threonine protein kinase, putative 0.0112 0.055 0.0695
Entamoeba histolytica hypothetical protein 0.0043 0.0121 0.0153
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0043 0.0121 0.0153
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0044 0.0128 0.0181
Echinococcus granulosus tyrosine protein kinase Fyn 0.01 0.0475 0.06
Onchocerca volvulus 0.0057 0.0205 0.0291
Loa Loa (eye worm) hypothetical protein 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni retinoic acid receptor RXR 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0024 0.0000060164 0.0000076111
Brugia malayi CHE-14 protein 0.0042 0.0113 0.0143
Schistosoma mansoni chromobox protein 0.0145 0.0757 0.0957
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0336 0.194 0.2454
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0092 0.0426 0.0244
Brugia malayi dihydrofolate reductase family protein 0.0473 0.2791 0.3531
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0336 0.194 0.2454
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0101 0.0481 0.0609
Brugia malayi hypothetical protein 0.0088 0.0402 0.0509
Brugia malayi SH2 domain containing protein 0.0044 0.0128 0.0162
Trypanosoma brucei pyruvate kinase 1 0.0066 0.0259 0.0228
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0025 0.001 0.0013
Brugia malayi serine/threonine-protein kinase plk-2 0.0112 0.055 0.0695
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0044 0.0128 0.0162
Schistosoma mansoni SH2A 0.0044 0.0128 0.0162
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0307 0.0069
Trypanosoma brucei polo-like protein kinase 0.0112 0.055 0.0519
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.1632 1 1
Brugia malayi Fes/CIP4 homology domain containing protein 0.0043 0.0121 0.0153
Loa Loa (eye worm) hypothetical protein 0.0064 0.025 0.0316
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0336 0.194 0.1914
Echinococcus granulosus GPCR family 2 0.0101 0.0481 0.0609
Schistosoma mansoni shc transforming protein 0.0044 0.0128 0.0162
Echinococcus multilocularis 0.0044 0.0128 0.0162
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.1159 0.7061 0.8932
Echinococcus multilocularis pyruvate kinase 0.0066 0.0259 0.0328
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0092 0.0426 0.0538
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.046 0.0581
Onchocerca volvulus 0.0092 0.0427 0.0605
Echinococcus multilocularis mitogen activated protein kinase 11 0.0983 0.5967 0.7548
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0048 0.0153 0.0193
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0112 0.055 0.0519
Brugia malayi SH2 domain containing protein 0.0044 0.0128 0.0162
Loa Loa (eye worm) hypothetical protein 0.0043 0.0121 0.0153
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.1128 0.1427
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.004 0.0051
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0057 0.0205 0.026
Trichomonas vaginalis set domain proteins, putative 0.0233 0.1304 0.165
Onchocerca volvulus 0.0043 0.0121 0.0172
Loa Loa (eye worm) hypothetical protein 0.0073 0.0307 0.0388
Echinococcus granulosus pyruvate kinase 0.0066 0.0259 0.0328
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0356 0.2065 0.2613
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0732 0.0926
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0121 0.0089
Echinococcus granulosus NCK adaptor protein 0.0088 0.0397 0.0502
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0043 0.0121 0.0153
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0846 0.1071
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0027
Loa Loa (eye worm) transcription factor SMAD2 0.0243 0.1361 0.1722
Entamoeba histolytica hypothetical protein 0.0043 0.0121 0.0153
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0983 0.5967 0.5954
Echinococcus granulosus tyrosine protein kinase Blk 0.0057 0.0205 0.026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0024 0.0000060164 0.0000076111
Loa Loa (eye worm) hypothetical protein 0.0046 0.0136 0.0172
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0024 0.0000060164 0.0000076111
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0306 0.0387
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0000060164 0.0000076111
Echinococcus granulosus nostrin 0.0043 0.0121 0.0153
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0092 0.0426 0.0538
Loa Loa (eye worm) RNA binding protein 0.0141 0.0732 0.0926
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0088 0.0397 0.0502
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0073 0.0092
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0092 0.0426 0.0538
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0307 0.0388
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0038 0.0048
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0101 0.0481 0.0609
Brugia malayi Variant SH3 domain containing protein 0.0088 0.0397 0.0502
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0073 0.0092
Echinococcus granulosus SH2 domain containing adapter protein F 0.0044 0.0128 0.0162
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0307 0.0388
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.004 0.0051
Echinococcus multilocularis expressed conserved protein 0.0092 0.0423 0.0535
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0092 0.0426 0.0538
Mycobacterium ulcerans lipase LipD 0.0073 0.0307 0.0069
Brugia malayi SH2 domain containing protein 0.0044 0.0128 0.0162
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.1632 1 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0846 0.1071
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.01 0.0475 0.06
Brugia malayi Protein kinase domain containing protein 0.0057 0.0205 0.026
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0057 0.0205 0.026
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.1295 0.7905 1
Plasmodium vivax geranylgeranyltransferase, putative 0.0092 0.0426 0.0426
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni sorting nexin 0.0043 0.0121 0.0153
Schistosoma mansoni formin binding protein and related proteins 0.0043 0.0121 0.0153
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0607 0.3629 0.459
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0618 0.0527
Trypanosoma cruzi polo-like protein kinase, putative 0.0112 0.055 0.0519
Echinococcus multilocularis NCK adaptor protein 0.0088 0.0397 0.0502
Echinococcus granulosus tyrosine protein kinase Src64B 0.01 0.0475 0.06
Entamoeba histolytica unconventional myosin IB 0.0043 0.0121 0.0153
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.1295 0.7905 0.7905
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.032 0.1842 0.233
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0054 0.0186 0.0236
Brugia malayi protein-tyrosine kinase 0.0043 0.0121 0.0153
Schistosoma mansoni Dab2-interacting protein-like 0.0043 0.0121 0.0153
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0732 0.0926
Schistosoma mansoni GTPase activating protein 0.0044 0.0128 0.0162
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0259 0.0328
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0336 0.194 0.2454
Loa Loa (eye worm) TK/FER protein kinase 0.0057 0.0205 0.026
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0092 0.0426 0.0538
Echinococcus granulosus tyrosine protein kinase shark 0.0057 0.0205 0.026
Echinococcus multilocularis thyroid hormone receptor alpha 0.0024 0.0000060164 0.0000076111
Echinococcus multilocularis tyrosine protein kinase Fgr 0.01 0.0475 0.06
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.1159 0.7061 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni dynamin-associated protein 0.0043 0.0121 0.0153
Schistosoma mansoni sorbin 0.0043 0.0121 0.0153
Onchocerca volvulus 0.0073 0.0307 0.0434
Brugia malayi Variant SH3 domain containing protein 0.0043 0.0121 0.0153
Giardia lamblia Prenyltransferase 0.0092 0.0426 0.0465
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0024 0.0000060164 0.0000076111
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0607 0.3629 0.459
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0846 0.1071
Echinococcus multilocularis tyrosine protein kinase Abl 0.01 0.0475 0.06
Loa Loa (eye worm) hypothetical protein 0.0051 0.0171 0.0217
Echinococcus granulosus tyrosine protein kinase Fyn 0.01 0.0475 0.06
Loa Loa (eye worm) SH2 domain-containing protein 0.0044 0.0128 0.0162
Echinococcus granulosus N chimaerin 0.0044 0.0128 0.0162
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0618 0.0588
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0000060164 0.0000076111
Trypanosoma brucei hypothetical protein, conserved 0.0336 0.194 0.1914
Entamoeba histolytica hypothetical protein, conserved 0.0043 0.0121 0.0153
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0307 0.0388
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0101 0.0481 0.0609
Brugia malayi SH2 domain containing protein 0.0044 0.0128 0.0162
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0336 0.194 0.2454
Onchocerca volvulus 0.0044 0.0128 0.0181
Trypanosoma brucei pyruvate kinase 1, putative 0.0066 0.0259 0.0228
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0024 0.0000060164 0.0000076111
Onchocerca volvulus 0.0043 0.0121 0.0172
Echinococcus granulosus tyrosine protein kinase Btk29A 0.01 0.0475 0.06
Echinococcus multilocularis tumor protein p63 0.0332 0.1918 0.2426
Leishmania major geranylgeranyltransferase, putative 0.0092 0.0426 0.0395
Echinococcus multilocularis pyruvate kinase 0.0066 0.0259 0.0328
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0000060164 0.0000076111
Echinococcus multilocularis microtubule associated protein 2 0.0748 0.4505 0.5699
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0473 0.2791 0.3723
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0092 0.0426 0.0538
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0038 0.0048
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0336 0.194 0.2454
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0121 0.0153
Brugia malayi SET domain containing protein 0.0026 0.0011 0.0013
Brugia malayi SRC-1 0.01 0.0475 0.06
Brugia malayi Src substrate cortactin 0.0043 0.0121 0.0153
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0443 0.056
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0336 0.194 0.1914
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0082 0.0359 0.0509
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0209 0.0264
Brugia malayi protein-tyrosine kinase 0.0057 0.0205 0.026
Loa Loa (eye worm) TK protein kinase 0.0057 0.0205 0.026
Entamoeba histolytica hypothetical protein 0.0073 0.0306 0.0387
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0307 0.0069
Onchocerca volvulus 0.0073 0.0307 0.0434
Trichomonas vaginalis chromobox protein, putative 0.0145 0.0757 0.0957
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0121 0.0089
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0043 0.0121 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni vav2 0.0044 0.0128 0.0162
Echinococcus granulosus tyrosine protein kinase Srms 0.0057 0.0205 0.026
Loa Loa (eye worm) hypothetical protein 0.0043 0.0121 0.0153
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0092 0.0426 0.0538
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0044 0.0128 0.0162
Loa Loa (eye worm) hypothetical protein 0.0066 0.0259 0.0328
Leishmania major hypothetical protein, conserved 0.0043 0.0121 0.0089
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0336 0.194 0.194
Brugia malayi beta-lactamase family protein 0.0073 0.0307 0.0388
Chlamydia trachomatis dihydrofolate reductase 0.0473 0.2791 1
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0044 0.0128 0.0162
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0092 0.0426 0.0538
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0336 0.194 0.2454
Brugia malayi Sex muscle abnormal protein 5 0.0088 0.0397 0.0502
Schistosoma mansoni tensin 0.0044 0.0128 0.0162
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.004 0.0051
Echinococcus granulosus tyrosine kinase 0.0057 0.0205 0.026
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0469 0.0593
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0121 0.0153
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.01 0.0475 0.06
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0618 0.0782
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0336 0.194 0.194
Loa Loa (eye worm) hypothetical protein 0.0272 0.1543 0.1951
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0307 0.0069
Onchocerca volvulus 0.0044 0.0128 0.0181
Echinococcus multilocularis tyrosine protein kinase Fyn 0.01 0.0475 0.06
Onchocerca volvulus 0.1159 0.7061 1
Brugia malayi SH2 domain containing protein 0.0057 0.0205 0.026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0307 0.0388
Brugia malayi cytokine inducible SH2-containing protein 5 0.0044 0.0128 0.0162
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0044 0.0128 0.0162
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.01 0.0475 0.06
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0043 0.0121 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0551 0.3281 0.4151
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0618 0.0527
Entamoeba histolytica hypothetical protein 0.0043 0.0121 0.0153
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0112 0.055 0.0695
Loa Loa (eye worm) hypothetical protein 0.0049 0.0154 0.0195
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0092 0.0426 0.0395
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0307 0.0069
Echinococcus multilocularis nostrin 0.0043 0.0121 0.0153
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0024 0.0000060164 0.0000076111
Echinococcus multilocularis ecdysone induced protein 78C 0.0024 0.0000060164 0.0000076111
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0983 0.5967 0.5954
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0043 0.0121 0.0153
Schistosoma mansoni hypothetical protein 0.0101 0.0481 0.0609
Loa Loa (eye worm) hypothetical protein 0.0024 0.0000060164 0.0000076111
Brugia malayi nuclear receptor NHR-88 0.0024 0.0000060164 0.0000076111
Echinococcus multilocularis GPCR, family 2 0.0101 0.0481 0.0609
Echinococcus multilocularis growth factor receptor bound protein 2 0.0088 0.0397 0.0502
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0044 0.0128 0.0162
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0259 0.0228
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0000060164 0.0000076111
Echinococcus granulosus c src tyrosine kinase 0.01 0.0475 0.06
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.1632 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.055 0.0695
Schistosoma mansoni microtubule-associated protein tau 0.0748 0.4505 0.5699
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.0043 0.0121 0.0153
Echinococcus multilocularis tyrosine protein kinase Src64B 0.01 0.0475 0.06
Echinococcus multilocularis N chimaerin 0.0044 0.0128 0.0162
Schistosoma mansoni tensin-related 0.0044 0.0128 0.0162
Onchocerca volvulus 0.0043 0.0121 0.0172
Trichomonas vaginalis chromobox protein, putative 0.0145 0.0757 0.0957
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0000060164 0.0000076111
Trypanosoma cruzi lanosterol synthase, putative 0.0092 0.0426 0.0395
Echinococcus granulosus geminin 0.055 0.3273 0.414
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0073 0.0092
Echinococcus multilocularis SHC transforming protein 3 0.0044 0.0128 0.0162
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0092 0.0426 0.0426
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0044 0.0128 0.0162
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0044 0.0128 0.0162
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0043 0.0121 0.0153
Trypanosoma cruzi hypothetical protein, conserved 0.0092 0.0426 0.0395
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0044 0.0128 0.0162
Trichomonas vaginalis p67phox protein, putative 0.0043 0.0121 0.0153
Trichomonas vaginalis chromobox protein, putative 0.0088 0.0398 0.0503
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0043 0.0121 0.0153
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0042 0.0113 0.0143
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0073 0.0092
Loa Loa (eye worm) hypothetical protein 0.0073 0.0307 0.0388
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0551 0.3281 0.326
Loa Loa (eye worm) hypothetical protein 0.032 0.1842 0.233
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0443 0.056
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0088 0.0397 0.0502
Schistosoma mansoni alpha glucosidase 0.0035 0.0073 0.0092
Echinococcus granulosus endophilin A3 0.0043 0.0121 0.0153
Loa Loa (eye worm) hypothetical protein 0.0082 0.0359 0.0454
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0000060164 0.0000076111
Onchocerca volvulus 0.0073 0.0307 0.0434
Brugia malayi Variant SH3 domain containing protein 0.0043 0.0121 0.0153
Brugia malayi Steroid receptor seven-up type 2 0.0024 0.0000060164 0.0000076111
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0307 0.0275
Loa Loa (eye worm) thyroid receptor interactor 0.0043 0.0121 0.0153
Onchocerca volvulus 0.0024 0.0000060164 0.0000085212
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0307 0.0069
Plasmodium falciparum pyruvate kinase 0.0066 0.0259 0.0259
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0443 0.056
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0732 0.0926
Schistosoma mansoni tyrosine kinase 0.0057 0.0205 0.026
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0141 0.0732 0.0926
Entamoeba histolytica hypothetical protein 0.0043 0.0121 0.0153
Plasmodium falciparum pyruvate kinase 2 0.0034 0.0061 0.0061
Onchocerca volvulus Putative cortactin 0.0043 0.0121 0.0172
Echinococcus multilocularis transfer RNA-Ala 0.0043 0.0121 0.0153
Brugia malayi beta-lactamase family protein 0.0073 0.0307 0.0388
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0618 0.0618
Loa Loa (eye worm) guanylate kinase 0.0043 0.0121 0.0153
Schistosoma mansoni hypothetical protein 0.004 0.0103 0.0131
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0073 0.0092
Trypanosoma cruzi lanosterol synthase, putative 0.0092 0.0426 0.0395
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0000060164 0.0000076111
Entamoeba histolytica SH2 domain containing protein 0.0044 0.0128 0.0162
Brugia malayi hypothetical protein 0.0057 0.0205 0.026
Schistosoma mansoni hypothetical protein 0.0219 0.1212 0.1533
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0607 0.3629 0.459
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0443 0.056
Loa Loa (eye worm) hypothetical protein 0.0043 0.0121 0.0153
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0443 0.056
Schistosoma mansoni steroid hormone receptor ad4bp 0.0024 0.0000060164 0.0000076111
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0019 0.0024
Schistosoma mansoni cpg binding protein 0.0028 0.0029 0.0037
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0024 0.0000060164 0.0000076111
Loa Loa (eye worm) heterochromatin protein 1 0.0145 0.0757 0.0957
Entamoeba histolytica protein kinase, putative 0.0048 0.0153 0.0193
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0307 0.0388
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0024 0.0000060164 0.0000076111
Echinococcus multilocularis geminin 0.055 0.3273 0.414
Brugia malayi Tyrosine-protein kinase abl-1 0.01 0.0475 0.06
Echinococcus multilocularis FTZ F1 alpha 0.0024 0.0000060164 0.0000076111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0000060164 0.0000076111
Onchocerca volvulus 0.0057 0.0205 0.0291
Onchocerca volvulus 0.0044 0.0128 0.0181
Loa Loa (eye worm) hypothetical protein 0.0101 0.0481 0.0609
Schistosoma mansoni hypothetical protein 0.0043 0.0121 0.0153
Echinococcus multilocularis tensin 0.0044 0.0128 0.0162
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0732 0.0926
Schistosoma mansoni tyrosine kinase 0.01 0.0475 0.06
Schistosoma mansoni nck2/grb4 0.0088 0.0397 0.0502
Echinococcus granulosus cpg binding protein 0.003 0.0039 0.005
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0092 0.0426 0.0538
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0024 0.0000060164 0.0000076111
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.004 0.0051
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0443 0.056
Echinococcus multilocularis thymidylate synthase 0.1159 0.7061 0.8932
Schistosoma mansoni tensin-related 0.0044 0.0128 0.0162
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0307 0.0388
Schistosoma mansoni pyruvate kinase 0.0066 0.0259 0.0328
Echinococcus granulosus tyrosine protein kinase Fyn 0.01 0.0475 0.06
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0024 0.0000060164 0.0000076111
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0618 0.0527
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0092 0.0426 0.0395
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0092 0.0426 0.0538
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0307 0.0069
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.1295 0.7905 1
Echinococcus granulosus tar DNA binding protein 0.0141 0.0732 0.0926
Loa Loa (eye worm) TK/FER protein kinase 0.0057 0.0205 0.026
Brugia malayi Variant SH3 domain containing protein 0.0043 0.0121 0.0153
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0057 0.0205 0.026
Onchocerca volvulus 0.0044 0.0128 0.0181
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0088 0.0397 0.0502
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0044 0.0128 0.0162
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0043 0.0121 0.0172
Brugia malayi MH2 domain containing protein 0.0243 0.1361 0.1722
Echinococcus multilocularis endophilin A3 0.0043 0.0121 0.0153
Schistosoma mansoni cpg binding protein 0.003 0.0039 0.005
Loa Loa (eye worm) hypothetical protein 0.0088 0.0402 0.0509
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0043 0.0121 0.0153
Echinococcus multilocularis mitogen activated protein kinase 14 0.0983 0.5967 0.7548
Onchocerca volvulus 0.0049 0.0154 0.0218
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0043 0.0121 0.0153
Entamoeba histolytica hypothetical protein 0.0073 0.0306 0.0387
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0092 0.0426 0.0538
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0443 0.056
Loa Loa (eye worm) pigment dispersing factor receptor c 0.032 0.1842 0.233
Giardia lamblia Rab geranylgeranyltransferase 0.0336 0.194 0.2395
Loa Loa (eye worm) hypothetical protein 0.0024 0.0000060164 0.0000076111
Echinococcus granulosus microtubule associated protein 2 0.0748 0.4505 0.5699
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.046 0.0581
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0307 0.0388
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.0043 0.0121 0.0089
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0607 0.3629 0.459
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0024 0.0000060164 0.0000076111
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0092 0.0426 0.0426
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0024 0.0000060164 0.0000076111
Trypanosoma brucei lanosterol synthase 0.0092 0.0426 0.0395
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0044 0.0128 0.0162
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0025 0.001 0.0013
Schistosoma mansoni hypothetical protein 0.0073 0.0306 0.0387
Echinococcus multilocularis protein dispatched 1 0.0048 0.015 0.0189
Entamoeba histolytica hypothetical protein 0.0043 0.0121 0.0153
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0336 0.194 0.2454
Plasmodium vivax prenyltransferase alpha subunit, putative 0.1295 0.7905 0.7905
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0306 0.0387
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0618 0.0527
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0618 0.0782
Mycobacterium ulcerans beta-lactamase 0.0073 0.0307 0.0069
Onchocerca volvulus 0.0024 0.0000000076446 0.000000010827
Brugia malayi RNA binding protein 0.0141 0.0732 0.0926
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0359 0.0454
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0101 0.0481 0.0609
Loa Loa (eye worm) TK/FER protein kinase 0.0057 0.0205 0.026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0038 0.0048
Echinococcus granulosus fch and double sh3 domains protein 2 0.0043 0.0121 0.0153
Loa Loa (eye worm) TAR-binding protein 0.0141 0.0732 0.0926
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0000060164 0.0000076111
Entamoeba histolytica hypothetical protein 0.0073 0.0306 0.0387
Brugia malayi Calcitonin receptor-like protein seb-1 0.032 0.1842 0.233
Echinococcus granulosus SH2 domain containing protein 7 0.0044 0.0128 0.0162
Brugia malayi Pyruvate kinase, muscle isozyme 0.0066 0.0259 0.0328
Brugia malayi CHD4 protein 0.0025 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0073 0.0307 0.0388
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0043 0.0121 0.0153
Giardia lamblia Rab geranylgeranyltransferase 0.0092 0.0426 0.0465
Loa Loa (eye worm) TK/FER protein kinase 0.0057 0.0205 0.026
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0043 0.0121 0.0153
Onchocerca volvulus 0.0057 0.0205 0.0291
Schistosoma mansoni hypothetical protein 0.055 0.3273 0.414
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0209 0.0264
Echinococcus granulosus signal transduction protein lnk realted 0.0044 0.0128 0.0162
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni suppressor of cytokine signaling 0.0044 0.0128 0.0162
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0044 0.0128 0.0181
Schistosoma mansoni tyrosine kinase 0.01 0.0475 0.06
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0983 0.5967 0.5954
Brugia malayi Guanylate kinase family protein 0.0043 0.0121 0.0153
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0043 0.0121 0.0153
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.046 0.0581
Brugia malayi CXXC zinc finger family protein 0.0028 0.0029 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.0057 0.0205 0.026
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0073 0.0092
Leishmania major pyruvate kinase 0.0066 0.0259 0.0228
Loa Loa (eye worm) hypothetical protein 0.0098 0.046 0.0581
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0024 0.0000060164 0.0000076111
Brugia malayi TAR-binding protein 0.0141 0.0732 0.0926
Schistosoma mansoni cpg binding protein 0.003 0.0039 0.005
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.01 0.0475 0.06
Echinococcus multilocularis intersectin 2 0.0043 0.0121 0.0153
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0307 0.0069
Brugia malayi Pyruvate kinase, M2 isozyme 0.0066 0.0259 0.0328
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0307 0.0388
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0121 0.0153
Schistosoma mansoni survival motor neuron protein 0.0055 0.0197 0.0249
Echinococcus multilocularis tyrosine protein kinase Srms 0.0057 0.0205 0.026
Brugia malayi Variant SH3 domain containing protein 0.0088 0.0397 0.0502
Loa Loa (eye worm) hypothetical protein 0.0219 0.1212 0.1533
Onchocerca volvulus 0.0336 0.194 0.2747
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0032 0.0032
Brugia malayi beta-lactamase 0.0073 0.0307 0.0388
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0024 0.0000060164 0.0000085212
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0618 0.0782
Trypanosoma cruzi protein farnesyltransferase, putative 0.0092 0.0426 0.0395
Plasmodium vivax SET domain protein, putative 0.003 0.0038 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0307 0.0388
Trypanosoma cruzi hypothetical protein, conserved 0.0336 0.194 0.1914
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0092 0.0426 0.0395
Loa Loa (eye worm) hypothetical protein 0.0073 0.0307 0.0388
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0983 0.5967 0.7548
Echinococcus granulosus chromobox protein 1 0.0145 0.0757 0.0957
Echinococcus multilocularis mitogen activated protein kinase 14 0.0983 0.5967 0.7548
Onchocerca volvulus 0.0233 0.1304 0.1847
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0092 0.0426 0.0538
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0307 0.0069
Loa Loa (eye worm) hypothetical protein 0.0088 0.0397 0.0502
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.004 0.0051
Echinococcus granulosus mitogen activated protein kinase 11 0.0983 0.5967 0.7548
Brugia malayi Heterochromatin protein 1 0.0145 0.0757 0.0957
Brugia malayi Variant SH3 domain containing protein 0.0044 0.0128 0.0162
Echinococcus multilocularis chromobox protein 1 0.0145 0.0757 0.0957
Loa Loa (eye worm) hypothetical protein 0.0043 0.0121 0.0153
Leishmania major farnesyltransferase beta subunit 0.0092 0.0426 0.0395
Onchocerca volvulus Serine\/threonine kinase homolog 0.0112 0.055 0.0778
Echinococcus granulosus tyrosine protein kinase Lyn 0.0104 0.0499 0.0632
Schistosoma mansoni hypothetical protein 0.0101 0.0481 0.0609
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.055 0.0695
Schistosoma mansoni dihydrofolate reductase 0.0473 0.2791 0.3531
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0073 0.0092
Mycobacterium tuberculosis Conserved protein 0.0073 0.0307 0.0069
Echinococcus multilocularis chromobox protein 1 0.0145 0.0757 0.0957
Onchocerca volvulus 0.0055 0.0197 0.0279
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0113 0.0143
Brugia malayi Protein kinase domain containing protein 0.0057 0.0205 0.026
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0197 0.0249
Schistosoma mansoni hypothetical protein 0.0101 0.0481 0.0609
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0359 0.0454
Schistosoma mansoni hypothetical protein 0.0044 0.0128 0.0162
Brugia malayi hypothetical protein 0.0029 0.0032 0.0041
Echinococcus multilocularis tyrosine kinase 0.0057 0.0205 0.026
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0000060164 0.0000076111
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Giardia lamblia Kinase, PLK 0.0112 0.055 0.0623
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0088 0.0398 0.0563
Echinococcus granulosus pyruvate kinase 0.0034 0.0061 0.0077
Echinococcus multilocularis tyrosine protein kinase Blk 0.0057 0.0205 0.026
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0092 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni eyes absent homolog 0.0088 0.0402 0.0509
Echinococcus granulosus dihydrofolate reductase 0.0473 0.2791 0.3531
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0038 0.0048
Echinococcus granulosus epidermal growth factor receptor kinase 0.0043 0.0121 0.0153
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0044 0.0128 0.0162
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0024 0.0000060164 0.0000076111
Brugia malayi Variant SH3 domain containing protein 0.0044 0.0128 0.0162
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0113 0.0143
Echinococcus granulosus tyrosine kinase 0.0057 0.0205 0.026
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0057 0.0205 0.026
Entamoeba histolytica pyruvate kinase, putative 0.0046 0.0136 0.0172
Plasmodium vivax pyruvate kinase, putative 0.0066 0.0259 0.0259
Loa Loa (eye worm) protein-tyrosine kinase 0.0043 0.0121 0.0153
Loa Loa (eye worm) hypothetical protein 0.0043 0.0121 0.0153
Schistosoma mansoni C-fyn 0.0043 0.0121 0.0153
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.1159 0.7061 1
Schistosoma mansoni tyrosine kinase 0.01 0.0475 0.06
Toxoplasma gondii pyruvate kinase PyKII 0.0034 0.0061 0.0061
Echinococcus granulosus suppressor of cytokine signaling 6 0.0044 0.0128 0.0162
Schistosoma mansoni hypothetical protein 0.0044 0.0128 0.0162
Schistosoma mansoni hypothetical protein 0.004 0.0103 0.0131
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0732 0.0926
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Trypanosoma cruzi protein farnesyltransferase, putative 0.0092 0.0426 0.0395
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0024 0.0000060164 0.0000076111
Plasmodium vivax pyruvate kinase 2, putative 0.0034 0.0061 0.0061
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.01 0.0475 0.06
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0000060164 0.0000076111
Onchocerca volvulus 0.0057 0.0205 0.0291
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0000060164 0.0000076111
Loa Loa (eye worm) MH2 domain-containing protein 0.0243 0.1361 0.1722
Echinococcus multilocularis tar DNA binding protein 0.0141 0.0732 0.0926
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0194 0.0194
Brugia malayi Variant SH3 domain containing protein 0.0043 0.0121 0.0153
Brugia malayi thymidylate synthase 0.1159 0.7061 0.8932
Schistosoma mansoni cell polarity protein 0.0043 0.0121 0.0153
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0092 0.0426 0.0538
Echinococcus multilocularis SH2 motif 0.0044 0.0128 0.0162
Brugia malayi nuclear hormone receptor 0.0024 0.0000060164 0.0000076111
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0032 0.0032
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0259 0.0367
Loa Loa (eye worm) thymidylate synthase 0.1159 0.7061 0.8932
Echinococcus granulosus expressed conserved protein 0.0044 0.0128 0.0162
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0259 0.0328
Echinococcus granulosus tyrosine protein kinase Src42A 0.0044 0.0128 0.0162
Mycobacterium tuberculosis Hypothetical protein 0.0551 0.3281 0.4443
Echinococcus multilocularis signal transduction protein lnk realted 0.0044 0.0128 0.0162
Echinococcus granulosus suppressor of cytokine signaling 7 0.0044 0.0128 0.0162
Loa Loa (eye worm) pyruvate kinase-PB 0.0046 0.0136 0.0172
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0044 0.0128 0.0162
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0307 0.0388
Echinococcus multilocularis Spectrin alpha actinin 0.0043 0.0121 0.0153
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0038 0.0048
Brugia malayi Latrophilin receptor protein 2 0.0101 0.0481 0.0609
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0043 0.0121 0.0153
Brugia malayi steroid hormone receptor 0.0024 0.0000060164 0.0000076111
Schistosoma mansoni apoptosis stimulating of P53 0.0043 0.0121 0.0153
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0043 0.0121 0.0153
Schistosoma mansoni alpha-glucosidase 0.0138 0.0708 0.0895
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0092 0.0426 0.0538
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0259 0.0328
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0024 0.0000060164 0.0000076111
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0044 0.0128 0.0162
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0044 0.0128 0.0162
Toxoplasma gondii pyruvate kinase PyK1 0.0066 0.0259 0.0259
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.055 0.0695
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0092 0.0426 0.0426
Trichomonas vaginalis esterase, putative 0.0073 0.0307 0.0388
Schistosoma mansoni eps8-related protein 0.0043 0.0121 0.0153
Echinococcus multilocularis SH2 motif 0.0044 0.0128 0.0162
Echinococcus multilocularis tensin 0.0044 0.0128 0.0162
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.055 0.0695
Loa Loa (eye worm) hypothetical protein 0.0043 0.0121 0.0153
Mycobacterium ulcerans hypothetical protein 0.0073 0.0307 0.0069
Schistosoma mansoni hypothetical protein 0.004 0.0103 0.0131
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0607 0.3629 0.459
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0043 0.0121 0.0153
Schistosoma mansoni pyruvate kinase 0.0034 0.0061 0.0077
Mycobacterium tuberculosis Conserved protein 0.0073 0.0307 0.0069
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0235 0.0297
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0162
Schistosoma mansoni hypothetical protein 0.004 0.0103 0.0131
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.004 0.0051
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0092 0.0426 0.0538
Schistosoma mansoni patched 1 0.0042 0.0113 0.0143
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.1295 0.7905 1
Schistosoma mansoni hypothetical protein 0.055 0.3273 0.414
Loa Loa (eye worm) TK/FER protein kinase 0.0057 0.0205 0.026
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0044 0.0128 0.0162
Onchocerca volvulus 0.0043 0.0121 0.0172
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.1632 1 1
Brugia malayi Tensin 0.0044 0.0128 0.0162
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0259 0.0328
Entamoeba histolytica protein kinase, putative 0.0043 0.0121 0.0153
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0073 0.0092
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0073 0.0092
Trypanosoma cruzi hypothetical protein, conserved 0.0092 0.0426 0.0395
Echinococcus multilocularis pyruvate kinase 0.0052 0.0174 0.022
Schistosoma mansoni run and tbc1 domain containing 0.0043 0.0121 0.0153
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0607 0.3629 0.459
Brugia malayi Pre-SET motif family protein 0.003 0.0038 0.0048
Leishmania major pyruvate kinase 0.0066 0.0259 0.0228
Brugia malayi P38 map kinase family protein 2 0.0983 0.5967 0.7548
Echinococcus multilocularis SH2 domain containing protein 7 0.0044 0.0128 0.0162
Trypanosoma brucei conserved protein 0.0043 0.0121 0.0089
Brugia malayi SH3 domain containing protein 0.0043 0.0121 0.0153
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.072 0.0911
Echinococcus granulosus pyruvate kinase 0.0034 0.0061 0.0077
Entamoeba histolytica BAR/SH3 domain containing protein 0.0043 0.0121 0.0153
Schistosoma mansoni tensin 0.0044 0.0128 0.0162
Trypanosoma cruzi polo-like protein kinase, putative 0.0112 0.055 0.0519
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0199 0.0251
Onchocerca volvulus 0.0047 0.0146 0.0206
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0073 0.0092
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0112 0.055 0.0695
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0259 0.0328
Echinococcus granulosus SH2 motif 0.0044 0.0128 0.0162
Brugia malayi Peripheral plasma membrane protein CASK 0.0043 0.0121 0.0153
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.055 0.0695
Brugia malayi Myosin tail family protein 0.0043 0.0121 0.0153
Loa Loa (eye worm) hypothetical protein 0.0024 0.0000060164 0.0000076111
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0092 0.0426 0.0538
Echinococcus multilocularis mitogen activated protein kinase 11 0.0983 0.5967 0.7548
Brugia malayi RNA recognition motif domain containing protein 0.0141 0.0732 0.0926
Toxoplasma gondii hypothetical protein 0.0959 0.5817 0.5817
Loa Loa (eye worm) hypothetical protein 0.0092 0.0426 0.0538
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0259 0.0367
Onchocerca volvulus 0.0057 0.0205 0.0291
Schistosoma mansoni RAR-like nuclear receptor 0.0024 0.0000060164 0.0000076111
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.004 0.0051
Loa Loa (eye worm) hypothetical protein 0.0092 0.0426 0.0538
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0044 0.0128 0.0162
Brugia malayi Protein kinase domain containing protein 0.0057 0.0205 0.026
Brugia malayi hypothetical protein 0.0073 0.0306 0.0387
Schistosoma mansoni suppressor of cytokine signaling 0.0044 0.0128 0.0162
Echinococcus granulosus survival motor neuron protein 1 0.0272 0.1543 0.1951
Loa Loa (eye worm) p53BP2 0.0043 0.0121 0.0153

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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