Detailed information for compound 578363

Basic information

Technical information
  • TDR Targets ID: 578363
  • Name: 1,3-bis(3-triethoxysilylpropyl)thiourea
  • MW: 484.798 | Formula: C19H44N2O6SSi2
  • H donors: 2 H acceptors: 0 LogP: 3.75 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCO[Si](OCC)(OCC)CCCNC(=S)NCCC[Si](OCC)(OCC)OCC
  • InChi: 1S/C19H44N2O6SSi2/c1-7-22-29(23-8-2,24-9-3)17-13-15-20-19(28)21-16-14-18-30(25-10-4,26-11-5)27-12-6/h7-18H2,1-6H3,(H2,20,21,28)
  • InChiKey: CHKNQQMXFCNQQZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N,N'-bis(3-triethoxysilylpropyl)thiourea
  • 69952-89-2
  • Bis-ttu
  • N,N'-Bis(3-(triethyoxysilyl)propyl)thiourea
  • Thiourea, N,N'-bis((3-triethoxysilyl)propyl)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis muscleblind protein 0.0158 0.1398 0.1392
Echinococcus multilocularis neutral amino acid transporter A 0.1024 1 1
Leishmania major GTP-binding protein, putative 0.0046 0.0294 0.2749
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0074 0.057 0.0563
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0201 0.0392
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.002 0.0033 0.0396
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0145 0.0137
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0018 0.0008 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0237 0.0463
Brugia malayi CXXC zinc finger family protein 0.0064 0.0474 0.0467
Brugia malayi ecdysteroid receptor 0.0031 0.0145 0.0137
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0066 0.0485 0.0478
Schistosoma mansoni cpg binding protein 0.0068 0.051 0.0503
Toxoplasma gondii exonuclease III APE 0.0038 0.0209 0.1892
Onchocerca volvulus 0.0533 0.5127 0.5055
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0066 0.0485 0.0478
Brugia malayi hypothetical protein 0.0028 0.0113 0.0106
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.004 0.023 0.0448
Onchocerca volvulus 0.0077 0.0597 0.0459
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.0597 0.059
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.3072 0.5991
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0597 0.059
Onchocerca volvulus 0.0077 0.0597 0.0459
Leishmania major trypanothione reductase 0.0043 0.0258 0.2402
Echinococcus multilocularis survival motor neuron protein 1 0.0264 0.2453 0.2448
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.019 0.0371
Brugia malayi jmjC domain containing protein 0.0066 0.0485 0.0478
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0017 0.001
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0209 0.03
Loa Loa (eye worm) hypothetical protein 0.0077 0.0597 0.059
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0513 0.0506
Onchocerca volvulus 0.0064 0.0474 0.0334
Echinococcus granulosus neutral amino acid transporter 0.1024 1 1
Echinococcus granulosus ubiquitin specific protease 41 0.0083 0.0658 0.0651
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.1267 0.1261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0292 0.057
Echinococcus granulosus geminin 0.0175 0.1574 0.1567
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0033 0.0273
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.3072 0.5991
Chlamydia trachomatis glutamate symporter 0.1024 1 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0017 0.001
Echinococcus multilocularis neutral amino acid transporter A 0.1024 1 1
Echinococcus multilocularis cpg binding protein 0.0068 0.051 0.0503
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0046 0.0294 0.0588
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0158 0.015
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0209 0.0201
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0097 0.0801 0.2492
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0106 0.0889 0.2876
Echinococcus granulosus neuropeptide s receptor 0.0516 0.4956 0.4953
Echinococcus granulosus survival motor neuron protein 1 0.0264 0.2453 0.2448
Loa Loa (eye worm) hypothetical protein 0.0031 0.0145 0.0137
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0145 0.0137
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0097 0.0801 0.0605
Loa Loa (eye worm) hypothetical protein 0.0077 0.0597 0.059
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.1024 1 1
Leishmania major importin beta-1 subunit, putative 0.0051 0.0341 0.3199
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.0597 0.0397
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0046 0.0294 0.2693
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0145 0.0137
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.0522 0.0515
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0018 0.0008 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.1267 0.1261
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0043 0.0263 0.2455
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0158 0.015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0237 0.0463
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0145 0.0137
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0054 0.0046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0513 0.0506
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0113 0.0953 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.1267 0.1261
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.0858 0.085
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0083 0.0658 0.0651
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0136 0.0264
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0145 0.0137
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0113 0.0953 0.186
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0136 0.0264
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0113 0.0953 0.3087
Trichomonas vaginalis ran, putative 0.0046 0.0294 0.0574
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0145 0.0137
Toxoplasma gondii ABC1 family protein 0.0077 0.0597 0.5544
Echinococcus granulosus cpg binding protein 0.0068 0.051 0.0503
Loa Loa (eye worm) hypothetical protein 0.0033 0.0158 0.015
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0597 0.6233
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0017 0.001
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0074 0.057 0.0563
Echinococcus multilocularis Excitatory amino acid transporter 0.1024 1 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0145 0.0137
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0108 0.0909 0.0715
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.1024 1 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0187 0.1689 0.1683
Brugia malayi steroid hormone receptor 0.0031 0.0145 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0145 0.0137
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0139 0.1216 0.1209
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0905 0.8817 0.8816
Plasmodium falciparum glutathione reductase 0.0043 0.0258 0.5544
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.004 0.023 0.0222
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0053 0.0365 0.5495
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0263 0.0513
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0145 0.0137
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0534 0.0526
Loa Loa (eye worm) excitatory amino acid transporter 0.1024 1 1
Echinococcus granulosus lysine specific demethylase 5A 0.0069 0.0522 0.0515
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0018 0.0008 0.0015
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0113 0.0953 0.0947
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.002 0.0033 0.0026
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0113 0.1622
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0145 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0164 0.032
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.3072 0.5991
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0145 0.0137
Loa Loa (eye worm) hypothetical protein 0.0031 0.0145 0.0137
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0209 0.0201
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.0522 0.0515
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0033 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0365 0.0712
Onchocerca volvulus Excitatory amino acid transporter homolog 0.1024 1 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0043 0.0263 0.3932
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0083 0.0658 0.0651
Plasmodium falciparum importin beta, putative 0.0063 0.0459 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0083 0.0658 0.0651
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.0522 0.0515
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.004 0.023 0.0222
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0158 0.015
Loa Loa (eye worm) thioredoxin reductase 0.0043 0.0258 0.025
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0145 0.0137
Echinococcus multilocularis ubiquitin specific protease 41 0.0083 0.0658 0.0651
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0145 0.0137
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0053 0.0365 0.1166
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0056 0.0049
Echinococcus multilocularis neutral amino acid transporter A 0.1024 1 1
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0145 0.0137
Loa Loa (eye worm) hypothetical protein 0.0264 0.2453 0.2448
Onchocerca volvulus 0.0077 0.0597 0.0459
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.1049 0.1042
Schistosoma mansoni survival motor neuron protein 0.0054 0.0368 0.0361
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.1267 0.1261
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0044 0.0037
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.0597 0.0397
Mycobacterium tuberculosis Probable dehydrogenase 0.0097 0.0801 0.0605
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0237 0.0463
Echinococcus granulosus Excitatory amino acid transporter 0.1024 1 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0145 0.0137
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0113 0.0953 0.186
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0113 0.0953 0.186
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0083 0.0658 0.0651
Loa Loa (eye worm) hypothetical protein 0.0077 0.0597 0.059
Schistosoma mansoni ran 0.0046 0.0294 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0161 0.0315
Plasmodium vivax glutathione reductase, putative 0.0043 0.0258 0.4245
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0053 0.0365 0.0358
Schistosoma mansoni hypothetical protein 0.0175 0.1574 0.1567
Schistosoma mansoni hypothetical protein 0.0175 0.1574 0.1567
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0209 0.0407
Echinococcus granulosus excitatory amino acid transporter 2 0.1024 1 1
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0145 0.0137
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0145 0.0137
Schistosoma mansoni ap endonuclease 0.0038 0.0209 0.0201
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.1267 0.1261
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.1267 0.1261
Echinococcus granulosus sodium:dicarboxylate symporter 0.1024 1 1
Schistosoma mansoni cpg binding protein 0.0064 0.0474 0.0467
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0159 0.1416 1
Echinococcus multilocularis excitatory amino acid transporter 2 0.1024 1 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.3072 0.5991
Echinococcus granulosus microtubule associated protein 2 0.0714 0.6918 0.6916
Loa Loa (eye worm) glutathione reductase 0.0043 0.0258 0.025
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0065
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.0597 0.0397
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0145 0.0137
Loa Loa (eye worm) hypothetical protein 0.0158 0.1398 0.1392
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0027 0.0102 0.1452
Echinococcus multilocularis excitatory amino acid transporter 2 0.1024 1 1
Schistosoma mansoni hypothetical protein 0.007 0.0534 0.0526
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0083 0.0658 0.1284
Schistosoma mansoni ap endonuclease 0.0038 0.0209 0.0201
Echinococcus multilocularis microtubule associated protein 2 0.0714 0.6918 0.6916
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0046 0.0294 0.0287
Echinococcus granulosus GPCR family 2 0.0033 0.0158 0.015
Onchocerca volvulus 0.0054 0.0368 0.0226
Loa Loa (eye worm) hypothetical protein 0.0068 0.0513 0.0506
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.004 0.023 0.0448
Loa Loa (eye worm) hypothetical protein 0.0028 0.0113 0.0106
Echinococcus granulosus neuropeptide receptor A26 0.0516 0.4956 0.4953
Brugia malayi Thioredoxin reductase 0.0043 0.0258 0.025
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0113 0.2337
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0145 0.0137
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.004 0.023 0.0725
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0209 0.3413
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0145 0.0137
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0209 0.3094
Brugia malayi Importin beta-1 subunit 0.0063 0.0459 0.0452
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.002 0.0033 0.0396
Toxoplasma gondii target of rapamycin (TOR), putative 0.0041 0.0237 0.2159
Leishmania major phosphatidylinositol 3-related kinase, putative 0.002 0.0033 0.0248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0263 0.0513
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0113 0.1115
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.1049 0.1042
Loa Loa (eye worm) hypothetical protein 0.0031 0.0145 0.0137
Loa Loa (eye worm) hypothetical protein 0.0074 0.057 0.0563
Leishmania major phosphatidylinositol 3-kinase, putative 0.002 0.0033 0.0248
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.0597 0.3218
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0145 0.0137
Echinococcus granulosus Excitatory amino acid transporter 0.1024 1 1
Toxoplasma gondii thioredoxin reductase 0.0043 0.0258 0.2354
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0065 0.0475 0.0467
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0033 0.0026
Echinococcus multilocularis excitatory amino acid transporter 3 0.1024 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0136 0.0264
Schistosoma mansoni hypothetical protein 0.0918 0.8949 0.8949
Echinococcus multilocularis sodium:dicarboxylate symporter 0.1024 1 1
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.1049 0.1042
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0018 0.0008 0.0002
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0052 0.0348 0.1111
Loa Loa (eye worm) beta-lactamase 0.0077 0.0597 0.059
Echinococcus granulosus GTP binding nuclear protein Ran 0.0046 0.0294 0.0287
Loa Loa (eye worm) hypothetical protein 0.0158 0.1398 0.1392
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.0597 0.0397
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0513 0.0506
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0209 0.0656
Schistosoma mansoni hypothetical protein 0.0033 0.0158 0.015
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0145 0.0137
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.3072 0.5991
Loa Loa (eye worm) hypothetical protein 0.0039 0.0217 0.021
Treponema pallidum fructose-bisphosphate aldolase 0.0326 0.3072 0.693
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.002 0.0033 0.0026
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0056 0.0049
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0145 0.0137
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0108 0.0909 0.0715
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0209 0.0407
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0053 0.0365 0.3779
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0053 0.0365 0.0358
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.004 0.023 0.3416
Echinococcus granulosus dnaJ subfamily B 0.0918 0.8949 0.8949
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0044 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0145 0.0137
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0158 0.015
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.1267 0.1261
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0018 0.0008 0.0001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0145 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0065
Echinococcus granulosus importin subunit beta 1 0.0063 0.0459 0.0452
Schistosoma mansoni microtubule-associated protein tau 0.0714 0.6918 0.6916
Treponema pallidum glutamate/aspartate transporter 0.0454 0.434 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0294 0.3028
Mycobacterium tuberculosis Conserved protein 0.0077 0.0597 0.0397
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0074 0.057 0.0563
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0018 0.0008 0.0001
Giardia lamblia GTOR 0.0053 0.0365 0.0829
Echinococcus multilocularis lysine specific demethylase 5A 0.0066 0.0485 0.0478
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0597 0.9064
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.0658 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0145 0.0137
Echinococcus granulosus neutral amino acid transporter A 0.1024 1 1
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0454 0.434 0.4336
Loa Loa (eye worm) hypothetical protein 0.007 0.0534 0.0526
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0597 0.059
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.004 0.023 0.0448
Giardia lamblia Fructose-bisphosphate aldolase 0.0326 0.3072 1
Leishmania major hypothetical protein, conserved 0.0077 0.0597 0.5659
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0454 0.434 0.4336
Mycobacterium tuberculosis Probable oxidoreductase 0.0108 0.0909 0.0715
Brugia malayi RNA, U transporter 1 0.0179 0.1612 0.1605
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0164 0.032
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0158 0.015
Brugia malayi jmjC domain containing protein 0.0069 0.0522 0.0515
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0145 0.0137
Schistosoma mansoni hypothetical protein 0.0033 0.0158 0.015
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0294 0.3028
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0209 0.2127
Loa Loa (eye worm) hypothetical protein 0.0031 0.0145 0.0137
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0008 0.0001
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.009 0.0731 0.2362
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0597 0.1165
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0469 0.4486 0.4482
Mycobacterium tuberculosis Probable reductase 0.0097 0.0801 0.0605
Echinococcus granulosus thioredoxin glutathione reductase 0.0043 0.0264 0.0256
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.0597 0.059
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0145 0.0137
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0145 0.0137
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0209 0.0201
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.0597 0.0397
Loa Loa (eye worm) hypothetical protein 0.0103 0.0858 0.085
Echinococcus granulosus excitatory amino acid transporter 2 0.1024 1 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0097 0.0801 0.0605
Brugia malayi hypothetical protein 0.0264 0.2453 0.2448
Schistosoma mansoni hypothetical protein 0.0033 0.0158 0.015
Echinococcus multilocularis dnaJ subfamily B 0.0918 0.8949 0.8949
Entamoeba histolytica Ran family GTPase 0.0046 0.0294 0.0934
Loa Loa (eye worm) hypothetical protein 0.0063 0.0459 0.0452
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0145 0.0137
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0078 0.0613 0.1196
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0145 0.0137
Schistosoma mansoni hypothetical protein 0.0033 0.0158 0.015
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0326 0.3072 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0068 0.0513 0.0506
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0018 0.0008 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.3072 0.5991
Echinococcus multilocularis GPCR, family 2 0.0033 0.0158 0.015
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0108 0.0909 0.3811
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.1049 0.6965
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.0597 0.059
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0145 0.0137
Mycobacterium ulcerans hypothetical protein 0.0077 0.0597 0.3218
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0068 0.0513 0.4754
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0135 0.0264
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0083 0.0658 0.1822
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0053 0.0365 0.3431
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0341 0.0665
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0658 0.1284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0237 0.0463
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0145 0.0137
Trypanosoma cruzi importin beta-1 subunit, putative 0.0051 0.0341 0.3523
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0065
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0078 0.0613 0.1196
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0145 0.0137
Loa Loa (eye worm) hypothetical protein 0.0077 0.0597 0.059
Loa Loa (eye worm) hypothetical protein 0.0031 0.0145 0.0137
Echinococcus multilocularis geminin 0.0175 0.1574 0.1567
Echinococcus multilocularis neuropeptide s receptor 0.0516 0.4956 0.4953
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0597 1
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0053 0.0365 0.1166
Plasmodium vivax importin-beta 2, putative 0.0063 0.0459 0.7657
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0326 0.3072 1
Schistosoma mansoni jumonji domain containing protein 0.0066 0.0485 0.0478
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0046 0.0294 0.4858
Echinococcus granulosus snurportin 1 0.0672 0.6508 0.6505
Brugia malayi Muscleblind-like protein 0.0158 0.1398 0.1392
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.0597 0.059
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.004 0.023 0.2349
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0145 0.0137
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0103 0.0858 0.085
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0083 0.0658 0.0651
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.0597 0.0397
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.1049 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0145 0.0137
Brugia malayi beta-lactamase 0.0077 0.0597 0.059
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0454 0.434 0.4336
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0056 0.0391 0.0916
Plasmodium vivax thioredoxin reductase, putative 0.0043 0.0258 0.4245
Entamoeba histolytica hypothetical protein 0.0051 0.0341 0.1087
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0145 0.0137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0145 0.0137
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0083 0.0658 0.6244
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0145 0.0137
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0145 0.0137
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0024 0.0073 0.101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0083 0.0658 0.1284
Schistosoma mansoni importin beta-1 0.0063 0.0459 0.0452
Trypanosoma brucei importin beta-1 subunit, putative 0.0063 0.0459 0.6941
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0263 0.0513
Toxoplasma gondii histone lysine methyltransferase SET1 0.0125 0.1071 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0237 0.0463
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0145 0.0137
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.1267 0.1261
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.1049 0.1042
Loa Loa (eye worm) hypothetical protein 0.0083 0.0658 0.0651
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0097 0.0801 0.0605
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.1267 0.1261
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0145 0.0137
Mycobacterium ulcerans lipase LipD 0.0077 0.0597 0.3218
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0597 0.6233
Echinococcus granulosus muscleblind protein 0.0158 0.1398 0.1392
Brugia malayi glutathione reductase 0.0043 0.0258 0.025
Schistosoma mansoni hypothetical protein 0.0054 0.0368 0.0361
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0053 0.0365 0.0358
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0672 0.6508 0.6505
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.1024 1 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0043 0.0258 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0237 0.0463
Loa Loa (eye worm) CXXC zinc finger family protein 0.0064 0.0474 0.0467
Plasmodium vivax SET domain protein, putative 0.0068 0.0513 0.8575
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0159 0.1416 0.1232
Echinococcus multilocularis neuropeptide receptor A26 0.0516 0.4956 0.4953
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0145 0.0137
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0209 0.1932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0237 0.0463
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0145 0.0137
Treponema pallidum glutamate transporter 0.0454 0.434 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0263 0.0513
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.3072 0.5991
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0018 0.0008 0.0001
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0018 0.0008 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0065
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0096 0.0792 0.0785
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0046 0.0294 0.0287
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0053 0.0365 0.5495
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0164 0.032
Mycobacterium tuberculosis Conserved protein 0.0077 0.0597 0.0397
Echinococcus granulosus neutral amino acid transporter A 0.1024 1 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.1049 0.6965
Onchocerca volvulus 0.0068 0.0513 0.0374
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0326 0.3072 0.5991
Leishmania major hypothetical protein, conserved 0.0028 0.0113 0.1013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0365 0.0712
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0161 0.0315
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0209 0.4457
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.1024 1 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0165 0.0158
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0113 0.1789
Schistosoma mansoni cpg binding protein 0.0068 0.051 0.0503
Schistosoma mansoni coup transcription factor 0.0031 0.0145 0.0137
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0113 0.0992
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0083 0.0658 0.2123
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0209 0.1911 0.1905
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0033 0.0165 0.1668
Loa Loa (eye worm) hypothetical protein 0.0077 0.0597 0.059
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0158 0.015
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0033 0.0273
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.1049 0.6965
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0597 0.1165
Echinococcus multilocularis thioredoxin glutathione reductase 0.0043 0.0264 0.0256
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.0658 0.6877
Mycobacterium tuberculosis Conserved protein 0.0077 0.0597 0.0397
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0145 0.0137
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0491 0.471 0.4597
Trichomonas vaginalis set domain proteins, putative 0.0533 0.5127 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0145 0.0137
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.0597 0.3218
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0017 0.001
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0083 0.0658 0.0651
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0209 0.1911 0.1905
Echinococcus granulosus histone lysine methyltransferase setb 0.0068 0.0513 0.0506
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0145 0.0137
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0158 0.015
Brugia malayi beta-lactamase family protein 0.0077 0.0597 0.059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0145 0.0137
Loa Loa (eye worm) hypothetical protein 0.0077 0.0597 0.059
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0068 0.0513 0.0506
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.002 0.0033 0.0026
Mycobacterium ulcerans beta-lactamase 0.0077 0.0597 0.3218
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0083 0.0658 0.0651
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0046 0.0294 0.4403
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0263 0.0513
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0113 0.2337
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0018 0.0008 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0365 0.0712
Loa Loa (eye worm) phosphatidylinositol 3 0.0053 0.0365 0.0358
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0056 0.0049
Echinococcus multilocularis snurportin 1 0.0672 0.6508 0.6505
Brugia malayi hypothetical protein 0.0018 0.0014 0.0007
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0053 0.0365 0.3779
Brugia malayi Pre-SET motif family protein 0.0469 0.4486 0.4482
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.1049 0.0858
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0145 0.0137
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0209 0.0201
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0018 0.0008 0.0002
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.0597 0.0397
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0145 0.0137
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0145 0.0137
Trypanosoma cruzi trypanothione reductase, putative 0.0043 0.0258 0.2646
Trypanosoma brucei importin beta-1 subunit, putative 0.0063 0.0459 0.6941
Toxoplasma gondii HEAT repeat-containing protein 0.0063 0.0459 0.4245
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0046 0.0294 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0033 0.0065
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0017 0.001
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0068 0.0513 0.0506
Trichomonas vaginalis esterase, putative 0.0077 0.0597 0.1165
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0097 0.0801 0.0605
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.0658 0.6877
Entamoeba histolytica hypothetical protein 0.009 0.0731 0.2362
Plasmodium falciparum thioredoxin reductase 0.0043 0.0258 0.5544
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.0858 0.085
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0209 0.2127
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0597 0.1165
Trichomonas vaginalis importin beta-1, putative 0.0051 0.0341 0.0665
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0341 0.0665
Echinococcus multilocularis Excitatory amino acid transporter 0.1024 1 1
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0113 0.0953 1
Brugia malayi beta-lactamase family protein 0.0077 0.0597 0.059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0145 0.0137
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0053 0.0365 0.3431
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0136 0.0264
Trypanosoma cruzi target of rapamycin kinase 3 0.0043 0.0263 0.2704
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0145 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0145 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0135 0.0264
Brugia malayi nuclear hormone receptor 0.0031 0.0145 0.0137
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0159 0.1416 1
Echinococcus multilocularis importin subunit beta 1 0.0063 0.0459 0.0452
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.004 0.023 0.0725
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0597 0.1165
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.1049 0.9796
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0145 0.0137
Schistosoma mansoni ran 0.0046 0.0294 0.0287
Brugia malayi Pre-SET motif family protein 0.0068 0.0513 0.0506
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0454 0.434 0.4336
Schistosoma mansoni hypothetical protein 0.0672 0.6508 0.6505
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0368 0.0361
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0135 0.0264
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0145 0.0137
Brugia malayi nuclear receptor NHR-88 0.0031 0.0145 0.0137
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0597 0.1165
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0046 0.0294 0.6344
Echinococcus multilocularis muscleblind protein 1 0.0158 0.1398 0.1392
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0145 0.0137
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0053 0.0365 0.0358
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0113 0.1115
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0209 0.1911 0.1905
Trypanosoma brucei trypanothione reductase 0.0043 0.0258 0.3848
Echinococcus granulosus excitatory amino acid transporter 3 0.1024 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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