Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | aldose reductase, putative | 0.0123 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0123 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0123 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0123 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0123 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0123 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0123 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0123 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Toxoplasma gondii | aldose reductase, putative | 0.0123 | 1 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0123 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0123 | 1 | 1 |
Onchocerca volvulus | 0.0123 | 1 | 0.5 | |
Giardia lamblia | Aldose reductase | 0.0123 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0123 | 1 | 1 |
Onchocerca volvulus | 0.0123 | 1 | 0.5 | |
Echinococcus multilocularis | aldo keto reductase | 0.0123 | 1 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0123 | 1 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0123 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0123 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0123 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0123 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0123 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0123 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0123 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0123 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0123 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0123 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0123 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0123 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0123 | 1 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0123 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0123 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0123 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0123 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0123 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0123 | 1 | 0.5 |
Onchocerca volvulus | 0.0123 | 1 | 0.5 | |
Leishmania major | prostaglandin f synthase, putative | 0.0123 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0123 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0123 | 1 | 0.5 |
Onchocerca volvulus | 0.0123 | 1 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0123 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0123 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0123 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0123 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0123 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0123 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0123 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0123 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0123 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0123 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0123 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0123 | 1 | 0.5 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0123 | 1 | 0.5 |
Onchocerca volvulus | 0.0123 | 1 | 0.5 | |
Schistosoma mansoni | pol-related | 0.0123 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0123 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0123 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0123 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0123 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0123 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0123 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0123 | 1 | 1 |
Onchocerca volvulus | 0.0123 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.