Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0006 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.1841 | 0.55 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0006 | 0 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.3348 | 0.3348 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.3348 | 0.3348 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 1 | 1 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0006 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.3348 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.3348 | 0.3348 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0006 | 0 | 0.5 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.3348 | 0.3348 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.3348 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.3348 | 0.3348 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.1841 | 0.55 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.1841 | 0.55 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.3348 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.3348 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.3348 | 0.3348 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0006 | 0 | 0.5 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.3348 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 1 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.3348 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.1841 | 0.55 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.3348 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.3348 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | unspecified product | 0.002 | 0.3348 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.3348 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.3348 | 1 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.3348 | 0.3348 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.3348 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.1841 | 0.55 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.3348 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.