Detailed information for compound 580335

Basic information

Technical information
  • TDR Targets ID: 580335
  • Name: ferrous; cyclopenta-1,3-diene; 1-[4-(cyclopen ta-2,4-dien-1-ylidenemethylamino)phenoxy]-N-m ethyl-methanimidate
  • MW: 363.211 | Formula: C19H19FeN2O2+
  • H donors: 1 H acceptors: 1 LogP: 5.7 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: C1C=CC=C1.C/N=C(/Oc1ccc(cc1)NC=C1C=CC=C1)\[O-].[Fe+2]
  • InChi: 1S/C14H14N2O2.C5H6.Fe/c1-15-14(17)18-13-8-6-12(7-9-13)16-10-11-4-2-3-5-11;1-2-4-5-3-1;/h2-10,16H,1H3,(H,15,17);1-4H,5H2;/q;;+2/p-1
  • InChiKey: MLMKQZKMAXWPMM-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

  • ferrous; cyclopenta-1,3-diene; 1-[4-(1-cyclopenta-2,4-dienylidenemethylamino)phenoxy]-N-methylmethanimidate
  • cyclopenta-1,3-diene; 1-[4-(cyclopenta-2,4-dien-1-ylidenemethylamino)phenoxy]-N-methyl-methanimidate; iron(2+)
  • ferrous; cyclopenta-1,3-diene; 1-[4-(cyclopenta-2,4-dien-1-ylidenemethylamino)phenoxy]-N-methyl-formimidate
  • cyclopenta-1,3-diene; 1-[4-(cyclopenta-2,4-dien-1-ylidenemethylamino)phenoxy]-N-methylmethanimidate; iron(2+)
  • ferrocene carbamate
  • cyclopenta-1,3-diene; 1-[4-(1-cyclopenta-2,4-dienylidenemethylamino)phenoxy]-N-methylmethanimidate; iron(+2) cation
  • ferrous; cyclopenta-1,3-diene; 1-[4-(1-cyclopenta-2,4-dienylidenemethylamino)phenoxy]-N-methyl-methanimidate
  • ferrous; cyclopenta-1,3-diene; 1-[4-(1-cyclopenta-2,4-dienylidenemethylamino)phenoxy]-N-methyl-formimidate
  • cyclopenta-1,3-diene; 1-[4-(1-cyclopenta-2,4-dienylidenemethylamino)phenoxy]-N-methyl-methanimidate; iron(+2) cation
  • 74006-19-2
  • Ferrocene, (((4-(((methylamino)carbonyl)oxy)phenyl)imino)methyl)-
  • (((4-(((Methylamino)carbonyl)oxy)phenyl)imino)methyl)ferrocene
  • CCRIS 1747

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae conserved hypothetical protein 0.0073 0.1431 0.4532
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Trypanosoma brucei heat shock protein 84, putative 0.0013 0.0135 0.0388
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0022 0.0023
Toxoplasma gondii ABC1 family protein 0.0073 0.1431 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.001 0.0066 0.0047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.6581 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.6581 1
Mycobacterium tuberculosis Conserved protein 0.0073 0.1431 0.1414
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.1836 0.2043
Schistosoma mansoni ap endonuclease 0.0019 0.0261 0.029
Schistosoma mansoni smad1 5 8 and 0.0008 0.0022 0.0025
Brugia malayi Protein kinase domain containing protein 0.0091 0.1836 0.3369
Toxoplasma gondii exonuclease III APE 0.0019 0.0261 0.1429
Loa Loa (eye worm) beta-lactamase 0.0073 0.1431 0.2616
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.062 0.0915
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0122 0.0126
Plasmodium falciparum heat shock protein 90 0.0033 0.0558 1
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0153 0.0242
Mycobacterium leprae putative cytochrome p450 0.001 0.0066 0.0149
Toxoplasma gondii heat shock protein HSP90 0.0033 0.0558 0.3609
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.6581 1
Brugia malayi beta-lactamase family protein 0.0073 0.1431 0.2616
Loa Loa (eye worm) hypothetical protein 0.0073 0.1431 0.2616
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0048 0.0048
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.002 0.0281 0.048
Brugia malayi beta-lactamase 0.0073 0.1431 0.2616
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.062 0.0915
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.1431 0.1481
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0073 0.0081
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0094
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.001 0.0066 0.0149
Mycobacterium ulcerans beta-lactamase 0.0073 0.1431 0.4532
Onchocerca volvulus 0.0073 0.1431 1
Brugia malayi CXXC zinc finger family protein 0.0029 0.0483 0.0855
Schistosoma mansoni cpg binding protein 0.0031 0.0519 0.0578
Giardia lamblia Fructose-bisphosphate aldolase 0.0309 0.6581 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.6581 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0073 0.0076
Schistosoma mansoni ferritin 0.0008 0.0019 0.0022
Trypanosoma brucei heat shock protein, putative 0.0033 0.0558 0.2782
Schistosoma mansoni hypothetical protein 0.0419 0.8986 1
Echinococcus multilocularis heat shock protein 90 0.0033 0.0558 0.0578
Echinococcus granulosus heat shock protein 0.0033 0.0558 0.0578
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.1559 0.2854
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0281 0.0312
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0423 0.0745
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0048 0.0048
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0151 0.3133 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.062 0.313
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0026 0.0412 0.6541
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0252 0.1051
Schistosoma mansoni tar DNA-binding protein 0.0255 0.5406 0.6016
Trichomonas vaginalis esterase, putative 0.0073 0.1431 0.2151
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.001 0.0066 0.0047
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1431 0.2151
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0039 0.0041
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.1431 0.2151
Brugia malayi nuclear hormone receptor 0.002 0.0281 0.048
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0151 0.3133 1
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.0412 0.0427
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0483 0.0855
Brugia malayi Cytochrome P450 family protein 0.0029 0.0471 0.0834
Schistosoma mansoni apoferritin-2 0.0008 0.0019 0.0022
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.1431 0.1414
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.001 0.0066 0.0149
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.6581 1
Schistosoma mansoni hypothetical protein 0.0079 0.1559 0.1735
Schistosoma mansoni inositol monophosphatase 0.0036 0.062 0.069
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Schistosoma mansoni Smad4 0.0008 0.0022 0.0025
Brugia malayi hypothetical protein 0.0011 0.0073 0.0094
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0013 0.0135 0.0139
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0281 0.1682
Loa Loa (eye worm) endoplasmin 0.0033 0.0558 0.0996
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.1431 0.1592
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0558 0.2782
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.1431 0.771
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.001 0.0066 0.0149
Schistosoma mansoni hypothetical protein 0.0171 0.3575 0.3979
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.1833 0.1897
Loa Loa (eye worm) TAR-binding protein 0.0255 0.5406 1
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0558 0.0657
Schistosoma mansoni hypothetical protein 0.0079 0.1559 0.1735
Echinococcus multilocularis neuropeptide s receptor 0.045 0.9661 1
Echinococcus granulosus intermediate filament protein 0.0027 0.0423 0.0438
Giardia lamblia Heat shock protein HSP 90-alpha 0.0033 0.0558 0.0471
Mycobacterium leprae Conserved hypothetical protein 0.001 0.0066 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0281 0.048
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0281 0.048
Brugia malayi Inositol-1 0.0036 0.062 0.111
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.6581 1
Trypanosoma cruzi Heat shock protein 83, putative 0.0033 0.0558 0.2782
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0261 0.0368
Echinococcus multilocularis ferritin 0.0008 0.0019 0.002
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.251 0.462
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0281 0.0291
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.1833 0.1897
Plasmodium vivax heat shock protein 86, putative 0.0033 0.0558 0.327
Echinococcus granulosus GPCR family 2 0.0079 0.1559 0.1613
Schistosoma mansoni hypothetical protein 0.017 0.3553 0.3954
Brugia malayi MH2 domain containing protein 0.0122 0.251 0.462
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.1431 0.1414
Loa Loa (eye worm) hypothetical protein 0.0073 0.1431 0.2616
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0281 0.048
Leishmania major heat shock protein, putative 0.0013 0.0135 0.0388
Trypanosoma brucei Heat shock protein 83, putative 0.0033 0.0558 0.2782
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.062 0.0642
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0261 0.1102
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0048 0.005
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.001 0.0066 0.0149
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0281 0.048
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.001 0.0066 0.0047
Loa Loa (eye worm) hypothetical protein 0.002 0.0281 0.048
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0281 0.0312
Onchocerca volvulus 0.0027 0.0423 0.2714
Schistosoma mansoni ferritin 0.0008 0.0019 0.0022
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0281 0.1682
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0281 0.048
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.1057 0.7262
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.1833 0.204
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0281 0.048
Schistosoma mansoni hypothetical protein 0.0171 0.3575 0.3979
Echinococcus granulosus Smad4 0.0008 0.0022 0.0023
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0281 0.0291
Loa Loa (eye worm) hypothetical protein 0.0027 0.0423 0.0745
Toxoplasma gondii heat shock protein 90, putative 0.0033 0.0558 0.3609
Echinococcus granulosus heat shock protein 90 0.0026 0.0412 0.0427
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.001 0.0066 0.0047
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.001 0.0066 0.0149
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.001 0.0066 0.0047
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0281 0.0291
Schistosoma mansoni ap endonuclease 0.0019 0.0261 0.029
Schistosoma mansoni lamin 0.0027 0.0423 0.0471
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.1833 0.1897
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.001 0.0066 0.0047
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0281 0.0291
Brugia malayi latrophilin 2 splice variant baaae 0.017 0.3553 0.6557
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Schistosoma mansoni tar DNA-binding protein 0.0255 0.5406 0.6016
Brugia malayi nuclear receptor RXR 0.0011 0.0073 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.0091 0.1836 0.2639
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.001 0.0066 0.0149
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.001 0.0066 0.0149
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0412 0.0599
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0048 0.005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0073 0.1431 0.2616
Brugia malayi hypothetical protein 0.001 0.0048 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0281 0.048
Trypanosoma brucei heat shock protein, putative 0.0033 0.0558 0.2782
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0037 0.0026
Onchocerca volvulus 0.0027 0.0423 0.2714
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Schistosoma mansoni nuclear receptor 0.001 0.0048 0.0054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.6581 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.1559 0.2854
Trypanosoma cruzi heat shock protein 90, putative 0.0033 0.0558 0.2782
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0261 0.4022
Schistosoma mansoni hypothetical protein 0.0079 0.1559 0.1735
Brugia malayi Nuclear hormone receptor E75 0.001 0.0048 0.0048
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0091 0.1836 0.3369
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0261 0.2981
Echinococcus multilocularis 0.001 0.0066 0.0068
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0412 0.0599
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0281 0.048
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.0412 0.1956
Echinococcus multilocularis endoplasmin 0.0026 0.0412 0.0427
Schistosoma mansoni heat shock protein 0.0013 0.0135 0.015
Echinococcus multilocularis smad 0.0008 0.0022 0.0023
Entamoeba histolytica hypothetical protein 0.0091 0.1836 0.2639
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0048 0.0048
Echinococcus multilocularis expressed protein 0.0008 0.0019 0.002
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0261 0.0443
Brugia malayi Cytochrome P450 family protein 0.0019 0.0252 0.0427
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.1431 0.4532
Echinococcus multilocularis lamin 0.0027 0.0423 0.0438
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.1559 0.1613
Schistosoma mansoni heat shock protein 0.0033 0.0558 0.0621
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.1203 0.1338
Loa Loa (eye worm) heat shock protein 75 0.0013 0.0135 0.0209
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.1833 0.204
Brugia malayi Calcitonin receptor-like protein seb-1 0.0249 0.5271 0.9749
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0281 0.0291
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.001 0.0066 0.0149
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0264 0.112
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0094
Brugia malayi steroid hormone receptor 0.002 0.0281 0.048
Onchocerca volvulus 0.002 0.0281 0.1682
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0412 0.1956
Loa Loa (eye worm) hypothetical protein 0.002 0.0281 0.048
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0022 0.0023
Brugia malayi Cytochrome P450 family protein 0.0019 0.0252 0.0427
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0281 0.048
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.1431 0.1592
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.062 0.313
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0281 0.048
Echinococcus granulosus geminin 0.0171 0.3575 0.3701
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.1833 0.3363
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0261 0.027
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.1559 0.1613
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0281 0.0291
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0048 0.0054
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0073 0.0076
Echinococcus multilocularis cpg binding protein 0.0031 0.0519 0.0537
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0281 0.048
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.1431 0.1414
Echinococcus granulosus dnaJ subfamily B 0.0419 0.8986 0.9301
Schistosoma mansoni nuclear hormone receptor 0.001 0.0048 0.0054
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.001 0.0066 0.0149
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.001 0.0066 0.0047
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.062 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0281 0.0291
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.1833 0.1897
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0281 0.0312
Schistosoma mansoni tar DNA-binding protein 0.0255 0.5406 0.6016
Schistosoma mansoni tar DNA-binding protein 0.0255 0.5406 0.6016
Echinococcus multilocularis dual specificity 0.0091 0.1836 0.19
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0281 0.048
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0091 0.1836 1
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0423 0.0745
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.001 0.0066 0.0149
Echinococcus granulosus expressed protein 0.0008 0.0019 0.002
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0281 0.0291
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.001 0.0066 0.0047
Toxoplasma gondii heat shock protein 75, putative 0.0013 0.0135 0.0504
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0153 0.0242
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0261 0.0196
Echinococcus multilocularis lamin dm0 0.0027 0.0423 0.0438
Loa Loa (eye worm) hypothetical protein 0.0091 0.1826 0.3349
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0281 0.1682
Echinococcus multilocularis GPCR, family 2 0.0079 0.1559 0.1613
Brugia malayi TAR-binding protein 0.0255 0.5406 1
Onchocerca volvulus 0.0073 0.1431 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0281 0.048
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Loa Loa (eye worm) hypothetical protein 0.002 0.0281 0.048
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.1431 0.1414
Brugia malayi nuclear receptor RXR 0.001 0.0048 0.0048
Mycobacterium leprae Probable lipase LipE 0.0073 0.1431 0.4532
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0048 0.0054
Trypanosoma brucei heat shock protein, putative 0.0033 0.0558 0.2782
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.062 0.0915
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0281 0.048
Onchocerca volvulus 0.0029 0.0483 0.3142
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0048 0.0054
Echinococcus granulosus heat shock protein 90 0.0033 0.0558 0.0578
Mycobacterium tuberculosis Conserved protein 0.0073 0.1431 0.1414
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0073 0.0094
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.1431 0.4532
Echinococcus granulosus neuropeptide receptor A26 0.045 0.9661 1
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Mycobacterium tuberculosis Conserved protein 0.0073 0.1431 0.1414
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0281 0.048
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0261 0.027
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.001 0.0066 0.0149
Echinococcus granulosus cytochrome P450 2K1 0.001 0.0066 0.0068
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0281 0.048
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.001 0.0066 0.0047
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Plasmodium vivax endoplasmin, putative 0.0033 0.0558 0.327
Schistosoma mansoni cpg binding protein 0.0031 0.0519 0.0578
Schistosoma mansoni smad1 5 8 and 0.0008 0.0022 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0255 0.5406 0.6016
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0048 0.005
Brugia malayi cytochrome P450 0.001 0.0066 0.0081
Echinococcus granulosus neuropeptide s receptor 0.045 0.9661 1
Loa Loa (eye worm) DR-78 0.001 0.0048 0.0048
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0252 0.1051
Brugia malayi Cytochrome P450 family protein 0.001 0.0066 0.0081
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0558 0.2782
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0022 0.0023
Brugia malayi RNA recognition motif domain containing protein 0.0255 0.5406 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0538 0.1666
Echinococcus multilocularis musashi 0.0027 0.0423 0.0438
Echinococcus granulosus cpg binding protein 0.0031 0.0519 0.0537
Trichomonas vaginalis heat shock protein, putative 0.002 0.0281 0.0399
Schistosoma mansoni thyroid hormone receptor 0.002 0.0281 0.0312
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.062 0.0753
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0558 0.0657
Entamoeba histolytica protein kinase, putative 0.0091 0.1836 0.2639
Giardia lamblia Grp94/Hsp90 0.0026 0.0412 0.0239
Schistosoma mansoni ferritin 0.0008 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0094
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0281 0.0312
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1431 0.2151
Brugia malayi conserved hypotetical protein 0.001 0.0048 0.0048
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0261 0.1102
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0048 0.0048
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0048 0.005
Brugia malayi nuclear receptor NHR-67 0.001 0.0048 0.0048
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.1431 0.1414
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Brugia malayi nuclear hormone receptor 0.001 0.0048 0.0048
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0048 0.005
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0026 0.0412 0.1262
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0013 0.0135 0.0139
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0281 0.0291
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0252 0.0427
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0558 0.2782
Brugia malayi Endoplasmin precursor 0.0033 0.0558 0.0996
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0091 0.1836 1
Schistosoma mansoni cytochrome P450 0.001 0.0066 0.0073
Mycobacterium ulcerans hypothetical protein 0.0073 0.1431 0.4532
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.001 0.0066 0.0149
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0281 0.0312
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0281 0.048
Brugia malayi intermediate filament protein 0.0027 0.0423 0.0745
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.001 0.0066 0.0047
Plasmodium falciparum endoplasmin, putative 0.002 0.0281 0.345
Trypanosoma brucei heat shock protein, putative 0.0033 0.0558 0.2782
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.001 0.0066 0.0149
Loa Loa (eye worm) hypothetical protein 0.002 0.0281 0.048
Schistosoma mansoni thyroid hormone receptor 0.002 0.0281 0.0312
Brugia malayi hypothetical protein 0.0011 0.0073 0.0094
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.001 0.0066 0.0149
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.001 0.0066 0.0047
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.0412 0.0394
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0281 0.0291
Loa Loa (eye worm) hypothetical protein 0.0012 0.0111 0.0165
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0073 0.0094
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0471 0.0834
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0261 0.0975
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.001 0.0066 0.0149
Schistosoma mansoni intermediate filament proteins 0.0027 0.0423 0.0471
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.1559 0.2854
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0048 0.005
Toxoplasma gondii Hsp90 domain-containing protein 0.0013 0.0135 0.0504
Leishmania major hypothetical protein, conserved 0.0073 0.1431 0.771
Loa Loa (eye worm) heat shock protein 90 0.0033 0.0558 0.0996
Trypanosoma brucei heat shock protein, putative 0.0033 0.0558 0.2782
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0048 0.005
Schistosoma mansoni ferritin light chain 0.0008 0.0019 0.0022
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0039 0.0031
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.1431 0.1481
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.001 0.0066 0.0149
Brugia malayi heat shock protein 90 0.0033 0.0558 0.0996
Loa Loa (eye worm) inositol-1 0.0036 0.062 0.111
Brugia malayi RNA binding protein 0.0255 0.5406 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.1826 0.3349
Loa Loa (eye worm) hypothetical protein 0.0073 0.1431 0.2616
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.001 0.0066 0.0149
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0026 0.0412 0.1956
Mycobacterium ulcerans heat shock protein 90 0.0026 0.0412 0.1262
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0013 0.0135 0.0626
Schistosoma mansoni ferritin 0.0008 0.0019 0.0022
Schistosoma mansoni endoplasmin 0.0033 0.0558 0.0621
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.001 0.0066 0.0047
Trypanosoma brucei heat shock protein, putative 0.0033 0.0558 0.2782
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0073 0.0094
Echinococcus multilocularis geminin 0.0171 0.3575 0.3701
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.1431 0.1414
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.001 0.0066 0.0047
Loa Loa (eye worm) hypothetical protein 0.0009 0.0027 0.0008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0249 0.5271 0.9749
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.1431 0.771
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.1833 0.3363
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0281 0.0312
Brugia malayi hypothetical protein 0.001 0.0048 0.0048
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0281 0.048
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.062 0.313
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0281 0.048
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1431 0.2151
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.001 0.0066 0.0149
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.001 0.0066 0.0149
Echinococcus granulosus tar DNA binding protein 0.0255 0.5406 0.5596
Schistosoma mansoni zinc finger protein 0.001 0.0048 0.0054
Entamoeba histolytica protein kinase, putative 0.0091 0.1836 0.2639
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0281 0.0291
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0094
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0281 0.0291
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Trypanosoma cruzi heat shock protein, putative 0.0013 0.0135 0.0388
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0281 0.048
Echinococcus granulosus endoplasmin 0.0026 0.0412 0.0427
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0252 0.0427
Brugia malayi ecdysone receptor 0.001 0.0048 0.0048
Mycobacterium ulcerans lipase LipD 0.0073 0.1431 0.4532
Echinococcus multilocularis neuropeptide receptor A26 0.045 0.9661 1
Echinococcus granulosus lamin dm0 0.0027 0.0423 0.0438
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0048 0.005
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0048 0.005
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0261 0.0776
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.001 0.0066 0.0047
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0261 0.0443
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.001 0.0048 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0281 0.048
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0558 0.2782
Loa Loa (eye worm) hypothetical protein 0.0013 0.0122 0.0185
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.1559 0.1613
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.1431 0.1414
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0281 0.0312
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.062 0.1929
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0281 0.048
Leishmania major cytochrome p450-like protein 0.0019 0.0252 0.1051
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0255 0.5406 1
Echinococcus granulosus ferritin 0.0008 0.0019 0.002
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Schistosoma mansoni cpg binding protein 0.0029 0.0483 0.0537
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.062 0.0642
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0281 0.048
Loa Loa (eye worm) hypothetical protein 0.0073 0.1431 0.2616
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0252 0.0747
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0281 0.0312
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0558 0.0822
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0281 0.048
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.1559 0.1613
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.062 0.406
Schistosoma mansoni smad1 5 8 and 0.0008 0.0022 0.0025
Loa Loa (eye worm) RNA binding protein 0.0255 0.5406 1
Schistosoma mansoni endoplasmin 0.0033 0.0558 0.0621
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.1431 0.771
Loa Loa (eye worm) hypothetical protein 0.0012 0.0111 0.0165
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0261 0.0242
Trypanosoma brucei heat shock protein, putative 0.0033 0.0558 0.2782
Echinococcus multilocularis Smad4 0.0008 0.0022 0.0023
Echinococcus granulosus smad 0.0008 0.0022 0.0023
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0281 0.0291
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0281 0.0291
Schistosoma mansoni nuclear receptor 0.001 0.0048 0.0054
Brugia malayi Latrophilin receptor protein 2 0.0079 0.1559 0.2854
Schistosoma mansoni ferritin light chain 0.0008 0.0019 0.0022
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.1431 0.2616
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0261 0.0368
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0249 0.5271 0.9749
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.251 0.462
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0091 0.1836 1
Schistosoma mansoni hypothetical protein 0.001 0.0066 0.0073
Schistosoma mansoni nuclear hormone receptor 0.002 0.0281 0.0312
Loa Loa (eye worm) hypothetical protein 0.002 0.0281 0.048
Echinococcus granulosus FTZ F1 alpha 0.002 0.0281 0.0291
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.001 0.0066 0.0047
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0252 0.1051
Schistosoma mansoni lamin 0.0027 0.0423 0.0471
Treponema pallidum fructose-bisphosphate aldolase 0.0309 0.6581 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0022 0.0023
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0122 0.0126
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.1431 0.2616
Brugia malayi ecdysteroid receptor 0.002 0.0281 0.048
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0281 0.0291
Trypanosoma brucei heat shock protein, putative 0.0033 0.0558 0.2782
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.001 0.0066 0.0047
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0423 0.0745
Echinococcus multilocularis dnaJ subfamily B 0.0419 0.8986 0.9301
Brugia malayi Nuclear hormone receptor E75 0.001 0.0048 0.0048
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0252 0.0427
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.062 0.313
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0538 0.052
Echinococcus multilocularis heat shock protein 90 0.0026 0.0412 0.0427
Trichomonas vaginalis endoplasmin, putative 0.002 0.0281 0.0399
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0412 0.0599
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.001 0.0066 0.0047
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.001 0.0066 0.0047
Loa Loa (eye worm) hypothetical protein 0.017 0.3553 0.6557
Onchocerca volvulus 0.0073 0.1431 1
Echinococcus multilocularis heat shock protein 0.0033 0.0558 0.0578
Echinococcus granulosus lamin 0.0027 0.0423 0.0438
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0281 0.048
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.0412 0.0239
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0281 0.0291
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0558 0.2782
Brugia malayi Hsp90 protein 0.0013 0.0135 0.0209
Brugia malayi nuclear receptor NHR-88 0.002 0.0281 0.048
Loa Loa (eye worm) hypothetical protein 0.0249 0.5271 0.9749
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.6581 1
Echinococcus multilocularis tar DNA binding protein 0.0255 0.5406 0.5596
Loa Loa (eye worm) hypothetical protein 0.0026 0.0413 0.0725
Schistosoma mansoni nuclear hormone receptor 0.001 0.0048 0.0054
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.1431 0.2151
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0091 0.1836 1
Schistosoma mansoni hypothetical protein 0.0079 0.1559 0.1735
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0048 0.005
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 0.6581 1
Trichomonas vaginalis heat shock protein, putative 0.0013 0.0135 0.0176
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Schistosoma mansoni heat shock protein 0.0033 0.0558 0.0621
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0261 0.0368
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0048 0.0048
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0048 0.0048
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0261 0.1102
Leishmania major heat shock protein 83-1 0.0033 0.0558 0.2782
Brugia malayi tailless protein 0.001 0.0048 0.0048
Plasmodium vivax hypothetical protein, conserved 0.0073 0.1431 1
Schistosoma mansoni smad 0.0008 0.0022 0.0025
Loa Loa (eye worm) cytochrome P450 0.001 0.0066 0.0081
Treponema pallidum heat shock protein 90 0.0026 0.0412 0.0599
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0151 0.3133 0.312
Schistosoma mansoni coup transcription factor 0.002 0.0281 0.0312
Brugia malayi beta-lactamase family protein 0.0073 0.1431 0.2616
Schistosoma mansoni inositol monophosphatase 0.0036 0.062 0.069
Brugia malayi nuclear receptor NHR-88 0.001 0.0048 0.0048
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0281 0.0291
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.001 0.0066 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.1833 0.204
Echinococcus granulosus dual specificity 0.0091 0.1836 0.19
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.001 0.0066 0.0149
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0073 0.1431 0.2616
Schistosoma mansoni apoferritin-2 0.0008 0.0019 0.0022
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0073 0.0081
Loa Loa (eye worm) hypothetical protein 0.002 0.0281 0.048
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0281 0.0312
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.001 0.0066 0.0047
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 0.6581 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0261 0.1102

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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