Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | MH2 domain-containing protein | 0.024 | 0.0202 | 0.0201 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0003 | 0.0003 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.002 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.002 | 0.0019 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.001 | 0.0009 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.002 | 0.0049 |
Onchocerca volvulus | 0.0081 | 0.006 | 0.7065 | |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0097 | 0.0074 | 0.0074 |
Echinococcus multilocularis | tumor protein p63 | 0.0347 | 0.0297 | 0.0296 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.002 | 0.0019 |
Echinococcus multilocularis | nervana 2 | 0.006 | 0.0041 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.008 | 0.008 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.0002 | 0.0002 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.002 | 0.0051 |
Giardia lamblia | Potassium-transporting ATPase alpha chain 1 | 0.0031 | 0.0015 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.001 | 0.0009 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0008 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.001 | 0.0009 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.002 | 0.0049 |
Echinococcus granulosus | nervana 2 | 0.006 | 0.0041 | 0.0041 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.002 | 0.0019 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0025 | 0.7503 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0097 | 0.0074 | 0.0074 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.002 | 0.0019 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0005 | 0.0429 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.0009 | 0.002 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0097 | 0.0074 | 0.0074 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.0002 | 0.0002 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.0109 | 0.0085 | 0.0084 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0014 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0005 | 0.0005 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0068 | 0.0067 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0139 | 0.0112 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.002 | 0.0019 |
Echinococcus multilocularis | GPCR, family 2 | 0.0048 | 0.0031 | 0.003 |
Echinococcus granulosus | GPCR family 2 | 0.0048 | 0.0031 | 0.003 |
Loa Loa (eye worm) | cytochrome P450 | 0.0014 | 0.0001 | 0.000003413 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0023 | 0.0009 | 0.0008 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.002 | 0.0019 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.001 | 0.0009 |
Echinococcus multilocularis | smad | 0.0016 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | sodium/potassium-transporting ATPase subunit alpha | 0.0027 | 0.0012 | 0.0011 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0031 | 0.003 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0014 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0048 | 0.0031 | 0.003 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0023 | 0.0008 | 0.0019 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0031 | 0.003 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0068 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.002 | 0.0019 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.002 | 0.0019 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0008 | 0.0007 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0005 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.0286 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0004 | 0.0003 |
Onchocerca volvulus | 0.0027 | 0.0012 | 0.0315 | |
Schistosoma mansoni | smad | 0.0016 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.0002 | 0.0002 |
Echinococcus multilocularis | Na+:K+ ATPase alpha subunit | 0.0031 | 0.0015 | 0.0015 |
Echinococcus granulosus | lamin | 0.0027 | 0.0012 | 0.0011 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.0005 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.001 | 0.0009 |
Schistosoma mansoni | lamin | 0.0027 | 0.0012 | 0.0011 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.002 | 0.0019 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0005 | 0.0004 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0005 | 0.0012 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.001 | 0.0009 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 1.1225 | 1 | 1 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 1.1225 | 1 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0012 | 0.0011 |
Echinococcus granulosus | Smad4 | 0.0016 | 0.0002 | 0.0002 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.005 | 0.0032 | 0.008 |
Brugia malayi | CHE-14 protein | 0.0042 | 0.0025 | 0.0024 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.0005 | 0.0005 |
Echinococcus multilocularis | ferritin | 0.0017 | 0.0003 | 0.0003 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0009 | 0.0008 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.006 | 0.0041 | 0.0041 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0005 | 0.0004 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0068 | 0.0067 |
Brugia malayi | Sodium/potassium-transporting ATPase alpha chain, putative | 0.0027 | 0.0012 | 0.0011 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0008 | 0.001 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.001 | 0.0714 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.006 | 0.0059 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0012 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0005 | 0.0005 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.002 | 0.0019 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.002 | 0.0019 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0003 | 0.0003 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0003 | 0.0003 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0014 | 0.0001 | 0.0002 |
Echinococcus multilocularis | expressed conserved protein | 0.0091 | 0.0069 | 0.0068 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.0025 | 0.0024 |
Echinococcus multilocularis | sodium:potassium transporting ATPase subunit | 0.006 | 0.0041 | 0.0041 |
Mycobacterium ulcerans | metal cation transporter p-type ATPase a | 0.003 | 0.0014 | 0.0014 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0031 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0024 | 0.0023 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0003 | 0.0002 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0012 | 0.0011 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0014 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.001 | 0.0009 |
Brugia malayi | cytochrome P450 | 0.0014 | 0.0001 | 0.000003413 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.4423 | 0.3933 | 1 |
Brugia malayi | Na,K-ATPase alpha subunit | 0.0031 | 0.0015 | 0.0015 |
Echinococcus granulosus | nervana 2 | 0.006 | 0.0041 | 0.0041 |
Brugia malayi | MH2 domain containing protein | 0.024 | 0.0202 | 0.0201 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0012 | 0.0011 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.001 | 0.0009 |
Schistosoma mansoni | hypothetical protein | 0.0104 | 0.008 | 0.008 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0004 | 0.0003 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0002 | 0.0002 |
Echinococcus granulosus | expressed conserved protein | 0.0091 | 0.0069 | 0.0068 |
Echinococcus granulosus | geminin | 0.0334 | 0.0286 | 0.0285 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0005 | 0.0005 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0005 | 0.0718 |
Brugia malayi | Smad1 | 0.0016 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.002 | 0.0019 |
Echinococcus granulosus | ferritin | 0.0017 | 0.0003 | 0.0003 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.001 | 0.0022 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.0002 | 0.0002 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.001 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.002 | 0.0019 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0139 | 0.0112 | 0.0111 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.001 | 0.0022 |
Leishmania major | cytochrome p450-like protein | 0.0023 | 0.0009 | 0.002 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0104 | 0.008 | 0.008 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.002 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0033 | 0.0032 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0068 | 0.0067 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.006 | 0.0041 | 0.0041 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.001 | 0.0009 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.002 | 0.004 |
Schistosoma mansoni | lamin | 0.0027 | 0.0012 | 0.0011 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.0005 | 0.0012 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0003 | 0.0003 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.002 | 0.0049 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0005 | 0.0004 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0005 | 0.0001 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0105 | 0.0081 | 0.008 |
Onchocerca volvulus | 0.0051 | 0.0033 | 0.3291 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0014 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0024 | 0.0023 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0005 | 0.001 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.024 | 0.0202 | 0.0201 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0014 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.0008 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0004 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0009 | 0.0008 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.002 | 0.5712 |
Echinococcus granulosus | microsomal glutathione S transferase 3 | 0.0109 | 0.0085 | 0.0084 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0023 | 0.0008 | 0.0004 |
Onchocerca volvulus | 0.0105 | 0.0081 | 1 | |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.0025 | 0.0024 |
Echinococcus granulosus | dihydrofolate reductase | 1.1225 | 1 | 1 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.0025 | 0.0024 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0081 | 0.006 | 0.0059 |
Schistosoma mansoni | na+/k+ atpase alpha subunit | 0.0031 | 0.0015 | 0.0015 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.002 | 0.0019 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0081 | 0.006 | 0.0059 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0068 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.001 | 0.0009 |
Onchocerca volvulus | 0.006 | 0.0041 | 0.4432 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0048 | 0.0031 | 0.003 |
Mycobacterium leprae | conserved hypothetical protein | 0.0023 | 0.0008 | 0.0007 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0005 | 0.001 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.002 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.001 | 0.0009 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.002 | 0.0019 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.0033 | 0.0032 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0003 | 0.0003 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.002 | 0.0019 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0031 | 0.003 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.001 | 0.0022 |
Schistosoma mansoni | Na+/K+ transporting ATPase subunit alpha | 0.0031 | 0.0015 | 0.0015 |
Brugia malayi | beta-lactamase | 0.0036 | 0.002 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0012 | 0.0011 |
Echinococcus granulosus | Na:K ATPase alpha subunit | 0.0031 | 0.0015 | 0.0015 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0012 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.0002 | 0.0002 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0097 | 0.0074 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0014 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.006 | 0.0041 | 0.0041 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0005 | 0.0005 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0023 | 0.0008 | 0.0019 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0012 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0011 | 0.0011 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0005 | 0.0004 |
Echinococcus multilocularis | nervana 2 | 0.006 | 0.0041 | 0.0041 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0031 | 0.003 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0005 | 0.0005 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0152 | 0.0123 | 0.0122 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0005 | 0.0004 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0105 | 0.0081 | 0.008 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.001 | 0.0714 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0005 | 0.0718 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0012 | 0.0011 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.0005 | 0.0014 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0068 | 0.0067 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0081 | 0.006 | 0.0059 |
Echinococcus multilocularis | nervana 2 | 0.006 | 0.0041 | 0.0041 |
Mycobacterium ulcerans | thymidylate synthase | 0.0105 | 0.0081 | 0.008 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.001 | 0.0009 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0031 | 0.003 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0152 | 0.0123 | 0.0122 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0012 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0005 | 0.0001 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0012 | 0.0011 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0014 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0003 | 0.0002 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0002 | 0.0002 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.4423 | 0.3933 | 1 |
Mycobacterium leprae | PROBABLE CATION-TRANSPORTER ATPASE I CTPI | 0.0025 | 0.0011 | 0.001 |
Onchocerca volvulus | 0.0027 | 0.0012 | 0.0315 | |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0023 | 0.0008 | 0.0007 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.002 | 0.0019 |
Onchocerca volvulus | 0.0036 | 0.002 | 0.1436 | |
Echinococcus granulosus | thymidylate synthase | 0.0105 | 0.0081 | 0.008 |
Echinococcus multilocularis | nervana 2 | 0.006 | 0.0041 | 0.0041 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.001 | 0.0009 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0005 | 0.0004 |
Brugia malayi | thymidylate synthase | 0.0105 | 0.0081 | 0.008 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0099 | 0.0076 | 0.0075 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0003 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0031 | 0.003 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0017 | 0.0003 | 0.0003 |
Chlamydia trachomatis | dihydrofolate reductase | 1.1225 | 1 | 1 |
Onchocerca volvulus | 0.006 | 0.0041 | 0.4432 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.001 | 0.0714 |
Schistosoma mansoni | sodium / potassium ATPase beta chain | 0.006 | 0.0041 | 0.0041 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0229 | 0.0192 | 0.0191 |
Echinococcus multilocularis | dihydrofolate reductase | 1.1225 | 1 | 1 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.4423 | 0.3933 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.4423 | 0.3933 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.0005 | 0.0005 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.4423 | 0.3933 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0014 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1364 | 0.1204 | 0.1204 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0048 | 0.0031 | 0.003 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0068 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0005 | 0.0004 |
Echinococcus granulosus | expressed protein | 0.0017 | 0.0003 | 0.0003 |
Echinococcus multilocularis | geminin | 0.0334 | 0.0286 | 0.0285 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.0109 | 0.0085 | 0.0084 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0002 | 0.0002 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0009 | 0.0008 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.001 | 0.0009 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0003 | 0.0003 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.002 | 0.5712 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.0009 | 0.002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0032 | 1 |
Echinococcus granulosus | sodium:potassium transporting ATPase subunit | 0.006 | 0.0041 | 0.0041 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0012 | 0.0011 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0024 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.0286 | 0.0285 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.002 | 0.0019 |
Brugia malayi | Cytochrome P450 family protein | 0.0014 | 0.0001 | 0.000003413 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0152 | 0.0123 | 0.0122 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.0068 | 0.0067 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.001 | 0.0009 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0012 | 0.0011 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | Na,K-ATPase alpha subunit | 0.0031 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0004 | 0.0003 |
Brugia malayi | Dihydrofolate reductase | 1.1225 | 1 | 1 |
Loa Loa (eye worm) | dihydrofolate reductase | 1.1225 | 1 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0023 | 0.0009 | 0.0008 |
Echinococcus granulosus | tumor protein p63 | 0.0347 | 0.0297 | 0.0296 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.0025 | 0.0024 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.002 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0004 | 0.0003 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.001 | 0.0009 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0081 | 0.006 | 0.0059 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0031 | 0.003 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.0005 | 0.0012 |
Trypanosoma brucei | cytochrome P450, putative | 0.0023 | 0.0009 | 0.0022 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.002 | 0.5712 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.002 | 0.0019 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.4423 | 0.3933 | 1 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0008 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0002 | 0.0002 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.006 | 0.0041 | 0.0041 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0053 | 0.0035 | 0.0035 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.006 | 0.0041 | 0.0041 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0008 | 0.0519 |
Echinococcus granulosus | nervana 2 | 0.006 | 0.0041 | 0.0041 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0005 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0024 | 0.0023 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.002 | 0.5712 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0023 | 0.0008 | 0.0007 |
Echinococcus multilocularis | protein dispatched 1 | 0.0048 | 0.003 | 0.003 |
Echinococcus multilocularis | expressed protein | 0.0017 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0004 | 0.0003 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0005 | 0.255 |
Toxoplasma gondii | MAPEG family protein | 0.0109 | 0.0085 | 0.0215 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0017 | 0.0003 | 0.0003 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0005 | 0.0429 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.0025 | 0.0024 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.002 | 0.0019 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0005 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0015 | 0.0015 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0005 | 0.001 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.002 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.0123 | 0.0122 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0012 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0005 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0025 | 0.0024 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0012 | 0.0011 |
Loa Loa (eye worm) | thymidylate synthase | 0.0105 | 0.0081 | 0.008 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.002 | 0.0019 |
Schistosoma mansoni | dihydrofolate reductase | 1.1225 | 1 | 1 |
Onchocerca volvulus | 0.0036 | 0.002 | 0.1436 | |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0005 | 0.255 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.002 | 0.0019 |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Hypothetical protein | 0.005 | 0.0032 | 0.0032 |
Echinococcus granulosus | smad | 0.0016 | 0.0002 | 0.0002 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0005 | 0.0005 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0003 | 0.0002 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.0068 | 0.0067 |
Echinococcus granulosus | nervana 2 | 0.006 | 0.0041 | 0.0041 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0005 | 0.0005 |
Echinococcus multilocularis | thymidylate synthase | 0.0105 | 0.0081 | 0.008 |
Brugia malayi | Cytochrome P450 family protein | 0.0053 | 0.0035 | 0.0035 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.006 | 0.0041 | 0.0041 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0005 | 0.0014 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.002 | 0.0019 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0005 | 0.001 |
Schistosoma mansoni | transmemberane protein | 0.006 | 0.0041 | 0.0041 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0017 | 0.0003 | 0.0003 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0009 | 0.0008 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.006 | 0.0041 | 0.0041 |
Echinococcus granulosus | microtubule associated protein 2 | 0.1364 | 0.1204 | 0.1204 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0006 | 0.0006 |
Onchocerca volvulus | 0.0036 | 0.002 | 0.1436 | |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0005 | 0.0005 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1364 | 0.1204 | 0.1204 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0017 | 0.0003 | 0.0003 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0023 | 0.0008 | 0.0019 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0031 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0041 | 0.0041 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.006 | 0.0041 | 0.0041 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0005 | 0.0005 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0033 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0041 | 0.0041 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0014 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.002 | 0.0019 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0005 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0074 | 0.0074 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.002 | 0.0049 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 1.1225 | 1 | 1 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.0025 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.002 | 0.0019 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0005 | 0.0777 |
Onchocerca volvulus | 0.003 | 0.0014 | 0.067 | |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.0109 | 0.0085 | 0.0084 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0005 | 0.0014 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0012 | 0.0011 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0005 | 0.0012 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.002 | 0.0019 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0009 | 0.0008 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.001 | 0.0009 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0005 | 0.0014 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0105 | 0.0081 | 0.008 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.006 | 0.0041 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0004 | 0.0003 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0008 | 0.001 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0017 | 0.0003 | 0.0003 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.002 | 0.5712 |
Brugia malayi | hypothetical protein | 0.005 | 0.0032 | 0.0032 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.002 | 0.0019 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.002 | 0.5712 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0005 | 0.0005 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.