Detailed information for compound 580597

Basic information

Technical information
  • TDR Targets ID: 580597
  • Name: silicon
  • MW: 32.1173 | Formula: H4Si
  • H donors: 0 H acceptors: 0 LogP: 0 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: [SiH4]
  • InChi: 1S/Si
  • InChiKey: XUIMIQQOPSSXEZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • monosilane
  • Silicones
  • 152284-21-4
  • 157383-37-4
  • 160371-18-6
  • 17375-03-0
  • 71536-23-7
  • 72516-01-9
  • 72516-02-0
  • 72516-03-1
  • 7440-21-3
  • 90337-93-2
  • 7803-62-5
  • 647675_ALDRICH
  • 647543_ALDRICH
  • Silicate solution
  • Silizium
  • 343250_ALDRICH
  • 633097_ALDRICH
  • 333891_ALDRICH
  • 215619_ALDRICH
  • 647764_ALDRICH
  • 204323_ALDRICH
  • 647772_ALDRICH
  • 647780_ALDRICH
  • CCRIS 6831
  • EINECS 232-263-4
  • Flots 100SCO
  • HSDB 6351
  • Silane, compressed [UN2203] [Flammable gas]
  • Silicon tetrahydride
  • UN2203
  • 647101_ALDRICH
  • 647705_ALDRICH
  • 647799_ALDRICH
  • 267414_ALDRICH
  • 647802_ALDRICH
  • CCRIS 6599
  • Defoamer S-10
  • EINECS 231-130-8
  • HSDB 5033
  • Polyeristalline silicon powder
  • Silicon dust
  • Silicon metal
  • Silicon powder, amorphous [UN1346] [Flammable solid]
  • Silicon, containing more than 99.99 per cent by weight of silicon
  • Silicone
  • UN1346
  • 553069_ALDRICH
  • 647810_ALDRICH
  • 85351_FLUKA
  • 267422_ALDRICH
  • Silicon standard for AAS
  • 316822_ALDRICH
  • Silicon atomic absorption standard solution
  • C06263
  • 646687_ALDRICH
  • 85354_FLUKA
  • 14Si
  • CHEBI:27573
  • Si
  • silicio
  • silicium
  • 475238_ALDRICH
  • 647535_ALDRICH

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0255 0.0253
Loa Loa (eye worm) inositol-1 0.0074 0.0794 0.1012
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0161 0.0557
Loa Loa (eye worm) hypothetical protein 0.0039 0.035 0.0444
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0006 0.0022
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0255 0.0283
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0377 0.2473
Schistosoma mansoni inositol monophosphatase 0.0074 0.0794 0.0885
Echinococcus multilocularis RUN 0.0021 0.0123 0.012
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0012 0.0006 0.0003
Brugia malayi Thioredoxin reductase 0.0046 0.0441 0.1371
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0255 0.0283
Echinococcus multilocularis caspase 3 0.0218 0.2585 0.2583
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0377 0.4408
Brugia malayi hypothetical protein 0.0015 0.0047 0.0146
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0012 0.0006 0.0022
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.003 0.0159
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0123 0.0135
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0161 0.0202
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0062 0.0204
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0255 0.0253
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0219 0.0681
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0255 0.0283
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0255 0.0283
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.035 0.4242 0.4743
Schistosoma mansoni hypothetical protein 0.0065 0.0669 0.0746
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Brugia malayi tailless protein 0.0015 0.0047 0.0146
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0165 0.0182
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.003 0.018
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0085 0.0083
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0012 0.0006 0.0018
Echinococcus granulosus caspase 8 0.0132 0.1518 0.1696
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0075 0.0072
Leishmania major short chain dehydrogenase/reductase, putative 0.0012 0.0006 0.0022
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.041 0.1466
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0629 0.0627
Loa Loa (eye worm) hypothetical protein 0.0024 0.0161 0.0202
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Entamoeba histolytica hypothetical protein 0.0012 0.0006 0.0038
Brugia malayi ecdysteroid receptor 0.0031 0.0255 0.0792
Loa Loa (eye worm) hypothetical protein 0.0132 0.1518 0.1939
Onchocerca volvulus 0.003 0.0237 0.0756
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.1518 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0034 0.0032
Schistosoma mansoni caspase-7 (C14 family) 0.035 0.4242 0.4743
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0075 0.0081
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Loa Loa (eye worm) glutathione reductase 0.0046 0.0441 0.0561
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0006 0.0022
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0313 0.1118
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0669 0.0852
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0062 0.0216
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0375
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0268 0.3219 0.4113
Leishmania major short chain dehydrogenase, putative 0.0012 0.0006 0.0022
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0255 0.0283
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0602 0.2157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0255 0.0323
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Echinococcus granulosus apoptotic protease activating factor 1 0.0123 0.1404 0.1569
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0004
Plasmodium falciparum importin beta, putative 0.006 0.0607 0.2174
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0676 0.2413
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0006 0.0022
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0062 0.0194
Mycobacterium ulcerans beta-lactamase 0.0039 0.035 0.1239
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.035 0.0347
Toxoplasma gondii carbonyl reductase 1, putative 0.0012 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0255 0.0323
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0062 0.0395
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0255 0.0792
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0377 0.0375
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0255 0.0792
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0132 0.1518 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1593 0.178
Leishmania major hypothetical protein, conserved 0.0039 0.035 0.2291
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0012 0.0006 0.0022
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0006 0.0022
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Brugia malayi kap beta 3 protein 0.0011 0.0002 0.0008
Plasmodium falciparum glutathione reductase 0.0046 0.0441 0.1578
Mycobacterium tuberculosis Probable reductase 0.0106 0.1184 0.3961
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0006 0.0022
Mycobacterium tuberculosis Conserved protein 0.0039 0.035 0.1156
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0153 0.1776 0.6376
Brugia malayi beta-lactamase 0.0039 0.035 0.1087
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.041 0.1466
Plasmodium vivax metacaspase 1, putative 0.0132 0.1518 0.5451
Loa Loa (eye worm) TAR-binding protein 0.0268 0.321 0.4102
Echinococcus multilocularis survival motor neuron protein 1 0.0264 0.316 0.3158
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0499 0.1784
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0132 0.1518 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0377 0.0419
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Schistosoma mansoni tar DNA-binding protein 0.0268 0.321 0.3589
Mycobacterium leprae Probable lipase LipE 0.0039 0.035 0.1239
Leishmania major hypothetical protein, conserved 0.0015 0.0053 0.0332
Trypanosoma brucei metacaspase MCA2 0.0132 0.1518 1
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0069 0.0215
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.1518 1
Entamoeba histolytica Ran family GTPase 0.0044 0.041 0.4795
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0079 0.0853 0.0851
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0074 0.0794 0.9306
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0067 0.0696 0.232
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0313 0.2052
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0006 0.0003
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0794 0.521
Brugia malayi Calcitonin receptor-like protein seb-1 0.0204 0.2413 0.7497
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.1518 1
Brugia malayi CXXC zinc finger family protein 0.003 0.0237 0.0736
Loa Loa (eye worm) hypothetical protein 0.0013 0.003 0.0035
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0255 0.0792
Schistosoma mansoni hypothetical protein 0.0023 0.0147 0.0162
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0062 0.0395
Schistosoma mansoni hypothetical protein 0.0725 0.894 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0313 0.2052
Echinococcus granulosus zinc finger protein 0.0021 0.0128 0.014
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.003 0.0093
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0375
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0012 0.0006 0.0003
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0377 0.2457
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0233 0.2783 1
Onchocerca volvulus 0.0029 0.0219 0.0698
Loa Loa (eye worm) hypothetical protein 0.0014 0.0034 0.004
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0268 0.321 0.4102
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0255 0.0253
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0012 0.0006 0.0003
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0123 0.0433
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0004
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0047 0.005
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0047 0.0045
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.1332 0.4457
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0006 0.0003
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0047 0.0146
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0006 0.0004
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0161 0.0557
Echinococcus multilocularis inositol monophosphatase 1 0.0074 0.0794 0.0791
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0794 0.522
Loa Loa (eye worm) hypothetical protein 0.0029 0.0219 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0255 0.0792
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0219 0.0277
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0047 0.005
Brugia malayi hypothetical protein 0.0079 0.0853 0.265
Brugia malayi hypothetical protein 0.0033 0.0273 0.0848
Brugia malayi conserved hypotetical protein 0.0015 0.0047 0.0146
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0012 0.0006 0.0022
Toxoplasma gondii thioredoxin reductase 0.0046 0.0441 0.1578
Schistosoma mansoni tar DNA-binding protein 0.0268 0.321 0.3589
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0466 0.3058
Brugia malayi Cell death protein 3 precursor 0.0256 0.3061 0.9511
Echinococcus multilocularis apoptotic protease activating factor 1 0.0123 0.1404 0.1402
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0311 0.0308
Plasmodium vivax glutathione reductase, putative 0.0046 0.0441 0.1578
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0012 0.0006 0.0012
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Brugia malayi nuclear hormone receptor 0.0031 0.0255 0.0792
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0161 0.1043
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0255 0.0792
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0047 0.0146
Trypanosoma cruzi metacaspase 5, putative 0.0132 0.1518 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0165 0.0182
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.035 0.1156
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0161 0.0499
Schistosoma mansoni tar DNA-binding protein 0.0268 0.321 0.3589
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0255 0.0283
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0123 0.0135
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0161 0.0557
Brugia malayi intermediate filament protein 0.0029 0.0219 0.0681
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0161 0.052
Brugia malayi hypothetical protein 0.0017 0.0069 0.0215
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0233 0.2783 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.035 0.0444
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0062 0.0204
Leishmania major short chain dehydrogenase-like protein 0.0012 0.0006 0.0022
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0794 0.521
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0062 0.0216
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0004
Schistosoma mansoni nuclear receptor 0.0015 0.0047 0.005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.1184 0.3961
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0006 0.0004
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0012
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0499 0.1784
Echinococcus granulosus steroid dehydrogenase 0.0012 0.0006 0.0004
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0313 0.3657
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0123 0.0135
Loa Loa (eye worm) hypothetical protein 0.0021 0.0123 0.0154
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0073 0.0225
Schistosoma mansoni transcription factor LCR-F1 0.0079 0.0853 0.0951
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0255 0.0323
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.035 0.0389
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.041 0.2674
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0047 0.0057
Schistosoma mansoni hypothetical protein 0.0079 0.0853 0.0951
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0123 0.012
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0123 0.012
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0012 0.0006 0.0004
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0069 0.0075
Mycobacterium leprae conserved hypothetical protein 0.0039 0.035 0.1239
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.003 0.018
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0233 0.2783 1
Brugia malayi Dehydrogenases, short chain protein 2 0.0012 0.0006 0.0018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0375
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0313 0.2035
Loa Loa (eye worm) hypothetical protein 0.0031 0.0255 0.0323
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0161 0.0557
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.003 0.018
Leishmania major importin beta-1 subunit, putative 0.0048 0.0466 0.3058
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0006 0.0003
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0006 0.0004
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0034 0.0035
Echinococcus granulosus snurportin 1 0.0636 0.7821 0.8748
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0233 0.2783 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0255 0.0253
Onchocerca volvulus 0.0054 0.0534 0.173
Schistosoma mansoni retinal dehydrogenase 0.0012 0.0006 0.0004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0132 0.1518 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0047 0.0045
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.003 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0377 0.2473
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.035 0.1239
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0012 0.0006 0.0012
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0039 0.035 0.0444
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0012 0.0006 0.0012
Brugia malayi ecdysone receptor 0.0015 0.0047 0.0146
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.035 0.1156
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0086
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0012
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0532 0.0677
Schistosoma mansoni cpg binding protein 0.0034 0.0282 0.0313
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0311 0.0345
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.1518 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0255 0.0283
Onchocerca volvulus 0.0123 0.1404 0.4578
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0062 0.0375
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0062 0.0216
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0375
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.035 0.1156
Trypanosoma brucei glycosyl hydrolase-like protein 0.0013 0.003 0.018
Echinococcus multilocularis oxidoreductase 0.0012 0.0006 0.0003
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0062 0.0395
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.008 0.0868 0.3105
Loa Loa (eye worm) oxidoreductase 0.0012 0.0006 0.0004
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.041 0.2674
Brugia malayi hypothetical protein 0.0021 0.0123 0.0382
Loa Loa (eye worm) hypothetical protein 0.0031 0.0255 0.0323
Trypanosoma cruzi metacaspase, putative 0.0132 0.1518 1
Schistosoma mansoni hypothetical protein 0.0054 0.0534 0.0595
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0233 0.2783 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0062 0.1401
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0004
Schistosoma mansoni survival motor neuron protein 0.0054 0.0534 0.0595
Brugia malayi oxidoreductase 0.0012 0.0006 0.0018
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0006 0.0004
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0132 0.1518 0.5451
Trypanosoma cruzi metacaspase, putative 0.0132 0.1518 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0083 0.009
Brugia malayi Bromodomain containing protein 0.0038 0.034 0.1057
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Brugia malayi nuclear receptor NHR-88 0.0031 0.0255 0.0792
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0669 0.0666
Loa Loa (eye worm) RNA binding protein 0.0268 0.321 0.4102
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0313 0.2052
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0047 0.0146
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0233 0.2783 1
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0123 0.0433
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0083 0.009
Trypanosoma brucei importin beta-1 subunit, putative 0.006 0.0607 0.3989
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0004
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.1184 0.3961
Trypanosoma cruzi ISWI complex protein 0.0015 0.0053 0.0311
Schistosoma mansoni lamin 0.0029 0.0219 0.0242
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0079 0.0853 0.0951
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.041 0.1275
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.035 0.2291
Loa Loa (eye worm) oxidoreductase 0.0012 0.0006 0.0004
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0062 0.0204
Schistosoma mansoni tar DNA-binding protein 0.0268 0.321 0.3589
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0012 0.0006 0.0004
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0669 0.2078
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0047 0.0045
Schistosoma mansoni hypothetical protein 0.0065 0.0669 0.0746
Entamoeba histolytica hypothetical protein, conserved 0.0012 0.0006 0.0038
Leishmania major dehydrogenase-like protein 0.0012 0.0006 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0083 0.009
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0377 0.9186
Plasmodium vivax importin-beta 2, putative 0.006 0.0607 0.2174
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0255 0.0323
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0012 0.0006 0.0004
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0669 0.0666
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0062 0.0375
Entamoeba histolytica hypothetical protein 0.0079 0.0853 1
Onchocerca volvulus Cell death protein 3 homolog 0.0256 0.3061 1
Schistosoma mansoni microtubule-associated protein tau 0.0721 0.8881 0.9935
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0147 0.0162
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0161 0.0557
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0062 0.0067
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0006 0.0004
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0132 0.1518 0.5451
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0006 0.0004
Leishmania major trypanothione reductase 0.0046 0.0441 0.2896
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0233 0.2783 1
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.003 0.0321
Echinococcus multilocularis zinc finger protein 0.0021 0.0128 0.0125
Trichomonas vaginalis ran, putative 0.0044 0.041 0.269
Brugia malayi nuclear receptor RXR 0.0017 0.0069 0.0215
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.041 0.0456
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0062 0.0204
Loa Loa (eye worm) hypothetical protein 0.0018 0.0085 0.0105
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0073 0.0225
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0053 0.0165
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0377 0.0419
Leishmania major short chain dehydrogenase/reductase, putative 0.0012 0.0006 0.0022
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0047 0.0057
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.003 0.018
Schistosoma mansoni alpha glucosidase 0.0036 0.0313 0.0348
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0233 0.2783 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0004
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0466 0.3044
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0006 0.0004
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0058 0.0593 0.0661
Brugia malayi Glycosyl hydrolases family 31 protein 0.0163 0.1898 0.5898
Plasmodium falciparum metacaspase 1 0.0132 0.1518 0.5451
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0313 0.2052
Echinococcus multilocularis caspase 2 0.0256 0.3061 0.306
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0004
Trypanosoma brucei importin beta-1 subunit, putative 0.006 0.0607 0.3989
Schistosoma mansoni caspase-7 (C14 family) 0.0256 0.3061 0.3422
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0047 0.005
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0012 0.0006 0.0038
Leishmania major GTP-binding protein, putative 0.0044 0.041 0.269
Schistosoma mansoni ran 0.0044 0.041 0.0456
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Onchocerca volvulus 0.0021 0.0123 0.0383
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0219 0.0277
Mycobacterium ulcerans lipase LipD 0.0039 0.035 0.1239
Echinococcus multilocularis transient receptor potential cation channel 0.0012 0.0006 0.0003
Loa Loa (eye worm) beta-lactamase 0.0039 0.035 0.0444
Brugia malayi hypothetical protein 0.0021 0.0123 0.0382
Echinococcus multilocularis snurportin 1 0.0636 0.7821 0.7821
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.1593 0.178
Schistosoma mansoni hypothetical protein 0.0015 0.0053 0.0056
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.035 0.2275
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.008 0.0868 0.3113
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.1184 0.3961
Brugia malayi dehydrogenases, short chain protein 2 0.0012 0.0006 0.0018
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.1332 0.4457
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0255 0.0792
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0794 0.522
Onchocerca volvulus 0.0039 0.035 0.1126
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0012 0.0006 0.0022
Entamoeba histolytica hypothetical protein, conserved 0.0012 0.0006 0.0038
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0047 0.0045
Loa Loa (eye worm) hypothetical protein 0.0123 0.1404 0.1793
Trypanosoma cruzi metacaspase 5, putative 0.0132 0.1518 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.035 0.0389
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Schistosoma mansoni cpg binding protein 0.0034 0.0282 0.0313
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0069 0.0067
Toxoplasma gondii oxidoreductase, putative 0.0012 0.0006 0.0012
Loa Loa (eye worm) dehydrogenase 0.0012 0.0006 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0062 0.0375
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0313 0.0974
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0255 0.0283
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0466 0.3058
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0047 0.0146
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0255 0.0792
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0255 0.0792
Loa Loa (eye worm) hypothetical protein 0.0233 0.2783 0.3556
Schistosoma mansoni hypothetical protein 0.0021 0.0119 0.0131
Echinococcus multilocularis musashi 0.0029 0.0219 0.0217
Schistosoma mansoni rab6-interacting 0.0021 0.0123 0.0135
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0006 0.0004
Onchocerca volvulus 0.0029 0.0219 0.0698
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0313 0.2052
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0006 0.0004
Loa Loa (eye worm) oxidoreductase 0.0012 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0086
Echinococcus granulosus importin subunit beta 1 0.006 0.0607 0.0676
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0233 0.2783 1
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.0006 0.0038
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Plasmodium vivax steroid dehydrogenase, putative 0.0012 0.0006 0.0012
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0255 0.0816
Onchocerca volvulus 0.0024 0.0161 0.0507
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0669 0.0746
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.1332 0.4775
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0085 0.0285
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0047 0.005
Loa Loa (eye worm) hypothetical protein 0.0071 0.0746 0.0951
Loa Loa (eye worm) hypothetical protein 0.0039 0.035 0.0444
Loa Loa (eye worm) hypothetical protein 0.0051 0.0499 0.0635
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0006 0.0012
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0012 0.0006 0.0022
Schistosoma mansoni carbonyl reductase 0.0012 0.0006 0.0004
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0534 0.166
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0161 0.1043
Echinococcus granulosus tar DNA binding protein 0.0268 0.321 0.3589
Echinococcus multilocularis cpg binding protein 0.0034 0.0282 0.028
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.035 0.2291
Echinococcus granulosus WW domain containing oxidoreductase 0.0012 0.0006 0.0004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0676 0.2413
Trichomonas vaginalis steroid dehydrogenase, putative 0.0012 0.0006 0.0022
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.035 0.2291
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0441 0.0491
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.041 0.269
Onchocerca volvulus 0.0094 0.104 0.3384
Trypanosoma cruzi metacaspase, putative 0.0132 0.1518 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0255 0.0253
Schistosoma mansoni hypothetical protein 0.0427 0.5208 0.5824
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0047 0.005
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0062 0.0395
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0377 0.0419
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0069 0.0086
Brugia malayi PHD-finger family protein 0.0027 0.0194 0.0604
Loa Loa (eye worm) hypothetical protein 0.0031 0.0255 0.0323
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0132 0.1518 1
Toxoplasma gondii oxidoreductase, putative 0.0012 0.0006 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0377 0.2473
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0375
Leishmania major hypothetical protein, conserved 0.0012 0.0006 0.0022
Schistosoma mansoni lamin 0.0029 0.0219 0.0242
Loa Loa (eye worm) hypothetical protein 0.0264 0.316 0.4038
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Mycobacterium ulcerans hypothetical protein 0.0039 0.035 0.1239
Brugia malayi nuclear receptor RXR 0.0015 0.0047 0.0146
Brugia malayi Inositol-1 0.0074 0.0794 0.2466
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0255 0.0283
Brugia malayi RNA recognition motif domain containing protein 0.0268 0.321 0.9972
Trypanosoma brucei trypanothione reductase 0.0046 0.0441 0.2896
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0161 0.0499
Loa Loa (eye worm) hypothetical protein 0.0028 0.0213 0.0269
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0441 0.0439
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0012 0.0006 0.0004
Toxoplasma gondii HEAT repeat-containing protein 0.006 0.0607 0.2174
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0794 0.522
Echinococcus granulosus lamin 0.0029 0.0219 0.0242
Brugia malayi follicle stimulating hormone receptor 0.0268 0.3219 1
Trypanosoma brucei Metacaspase-4 0.0132 0.1518 1
Brugia malayi nuclear hormone receptor 0.0015 0.0047 0.0146
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0082 0.0102
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0255 0.0253
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0132 0.1518 1
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0062 0.0395
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0313 0.2052
Brugia malayi RNA, U transporter 1 0.0169 0.1982 0.6157
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0255 0.0323
Trypanosoma brucei metacaspase 5, putative 0.0132 0.1518 1
Schistosoma mansoni nuclear receptor 0.0015 0.0047 0.005
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0377 0.0419
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Trypanosoma cruzi metacaspase, putative 0.0132 0.1518 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0132 0.1518 1
Entamoeba histolytica short chain dehydrogenase family protein 0.0012 0.0006 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0255 0.0792
Echinococcus multilocularis lamin dm0 0.0029 0.0219 0.0217
Schistosoma mansoni tar DNA-binding protein 0.0268 0.321 0.3589
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0004
Mycobacterium tuberculosis Conserved protein 0.0039 0.035 0.1156
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Echinococcus granulosus oxidoreductase 0.0012 0.0006 0.0004
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0499 0.1784
Schistosoma mansoni hypothetical protein 0.0123 0.1404 0.1569
Entamoeba histolytica hypothetical protein 0.0048 0.0466 0.5452
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Loa Loa (eye worm) hypothetical protein 0.0041 0.0371 0.0471
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0074 0.0794 0.2837
Leishmania major pteridine reductase 1 0.0012 0.0006 0.0022
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.035 0.1239
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0377 0.0419
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0006 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0073 0.0225
Onchocerca volvulus 0.0039 0.035 0.1126
Leishmania major hypothetical protein, conserved 0.0051 0.0499 0.3273
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0012 0.0006 0.0022
Trypanosoma brucei metacaspase 0.0132 0.1518 1
Schistosoma mansoni hypothetical protein 0.0725 0.894 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0065 0.0676 0.0754
Loa Loa (eye worm) hypothetical protein 0.0018 0.0085 0.0105
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.035 0.1156
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0499 0.3273
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0255 0.0283
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.1898 0.1896
Entamoeba histolytica hypothetical protein 0.0079 0.0853 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0009 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0255 0.0792
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0636 0.7821 1
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0006 0.0004
Brugia malayi nuclear receptor NHR-88 0.0015 0.0047 0.0146
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0012 0.0006 0.0038
Brugia malayi RNA binding protein 0.0268 0.321 0.9972
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.008 0.0868 0.3113
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0161 0.052
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0161 0.1859
Trypanosoma brucei oxidoreductase-like protein 0.0012 0.0006 0.0022
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.0676 0.2252
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0163 0.1898 0.2425
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0012 0.0006 0.0004
Echinococcus multilocularis microtubule associated protein 2 0.0721 0.8881 0.8881
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0233 0.2783 1
Brugia malayi Dehydrogenases, short chain protein 30 0.0012 0.0006 0.0018
Echinococcus multilocularis dnaJ subfamily B 0.0427 0.5208 0.5207
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0067 0.0696 0.2486
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0255 0.0792
Leishmania major glycosyl hydrolase-like protein 0.0013 0.003 0.018
Plasmodium falciparum metacaspase-like protein 0.0132 0.1518 0.5451
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0006 0.0022
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Brugia malayi hypothetical protein 0.0012 0.0006 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0255 0.0792
Entamoeba histolytica hypothetical protein 0.0079 0.0853 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0047 0.0045
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0012 0.0006 0.0012
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0062 0.0216
Loa Loa (eye worm) hypothetical protein 0.0018 0.0085 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0255 0.0323
Brugia malayi Importin beta-1 subunit 0.006 0.0607 0.1886
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0012 0.0006 0.0022
Echinococcus multilocularis retinol dehydrogenase 13 0.0012 0.0006 0.0003
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.003 0.0159
Plasmodium vivax hypothetical protein, conserved 0.0132 0.1518 0.5451
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Echinococcus granulosus peptidase Clp S14 family 0.0153 0.1776 0.1985
Brugia malayi Probable ClpP-like protease 0.0233 0.2783 0.8647
Echinococcus multilocularis peptidase Clp (S14 family) 0.0153 0.1776 0.1774
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.041 0.0521
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0123 0.0154
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0794 0.522
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0377 0.0375
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0255 0.0283
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0161 0.1859
Schistosoma mansoni inositol monophosphatase 0.0074 0.0794 0.0885
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0009 0.0028
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0161 0.0499
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0074 0.0794 0.2846
Echinococcus granulosus geminin 0.0725 0.894 1
Toxoplasma gondii ABC1 family protein 0.0039 0.035 0.1249
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0161 0.1859
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0255 0.0816
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0062 0.006
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0138 0.1593 0.2034
Brugia malayi glutathione reductase 0.0046 0.0441 0.1371
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.1593 0.178
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0206 0.2442 0.7975
Loa Loa (eye worm) hypothetical protein 0.0256 0.3061 0.3912
Echinococcus granulosus hypothetical protein 0.0012 0.0006 0.0004
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0313 0.2052
Leishmania major short chain dehydrogenase, putative 0.0012 0.0006 0.0022
Schistosoma mansoni alpha-glucosidase 0.014 0.1615 0.1804
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0441 0.288
Brugia malayi hypothetical protein 0.0015 0.0047 0.0146
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0629 0.0701
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0006 0.0003
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.035 0.1156
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.1593 0.1591
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0395
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0499 0.1784
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0255 0.0283
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0255 0.0323
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0255 0.0283
Loa Loa (eye worm) hypothetical protein 0.0039 0.035 0.0444
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.035 0.2275
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0313 0.3657
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0062 0.0395
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0132 0.1518 1
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0062 0.0216
Loa Loa (eye worm) oxidoreductase 0.0012 0.0006 0.0004
Schistosoma mansoni zinc finger protein 0.0021 0.0128 0.014
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0441 0.1464
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0069 0.0075
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0255 0.0283
Onchocerca volvulus 0.0015 0.0047 0.0135
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0083 0.008
Echinococcus granulosus cpg binding protein 0.0034 0.0282 0.0313
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0012 0.0006 0.0004
Echinococcus granulosus lysosomal alpha glucosidase 0.0163 0.1898 0.2121
Echinococcus granulosus caspase 3 0.0218 0.2585 0.289
Loa Loa (eye worm) hypothetical protein 0.0039 0.035 0.0444
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0161 0.0202
Loa Loa (eye worm) hypothetical protein 0.0044 0.0416 0.0529
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0138 0.1593 0.495
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0161 0.0557
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0377 0.2457
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0255 0.0323
Loa Loa (eye worm) hypothetical protein 0.006 0.0607 0.0773
Leishmania major 3-keto-dihydrosphingosine reductase 0.0012 0.0006 0.0022
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0161 0.0557
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0062 0.0395
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0676 0.0674
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.1184 0.3961
Brugia malayi latrophilin 2 splice variant baaae 0.0139 0.1606 0.4989
Echinococcus granulosus microtubule associated protein 2 0.0721 0.8881 0.9935
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0255 0.0253
Schistosoma mansoni ran 0.0044 0.041 0.0456
Loa Loa (eye worm) DR-78 0.0015 0.0047 0.0057
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0047 0.0135
Leishmania major hypothetical protein, conserved 0.0012 0.0006 0.0022
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.1184 0.3961
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0233 0.2783 0.2781
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0377 0.0375
Entamoeba histolytica hypothetical protein 0.0079 0.0853 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0676 0.0754
Echinococcus multilocularis caspase 0.035 0.4242 0.4241
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0132 0.1518 1
Echinococcus granulosus lamin dm0 0.0029 0.0219 0.0242
Brugia malayi hypothetical protein 0.0123 0.1404 0.4364
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0047 0.0057
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0047 0.0045
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0313 0.0398
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0165 0.0162
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0044 0.041 1
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0255 0.0283
Loa Loa (eye worm) hypothetical protein 0.0031 0.0255 0.0323
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1593 0.178
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Loa Loa (eye worm) hypothetical protein 0.0065 0.0669 0.0852
Brugia malayi TAR-binding protein 0.0268 0.321 0.9972
Trypanosoma brucei ISWI complex protein 0.0015 0.0053 0.0332
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0006 0.0004
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0047 0.0146
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.0006 0.0038
Onchocerca volvulus 0.0039 0.035 0.1126
Schistosoma mansoni zinc finger protein 0.0015 0.0053 0.0056
Leishmania major metacaspase, putative 0.0132 0.1518 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0249 0.2981 1
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0012
Plasmodium falciparum thioredoxin reductase 0.0046 0.0441 0.1578
Schistosoma mansoni intermediate filament proteins 0.0029 0.0219 0.0242
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0669 0.0746
Echinococcus multilocularis importin subunit beta 1 0.006 0.0607 0.0605
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0069 0.0075
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.008 0.0868 0.2961
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0086
Schistosoma mansoni alpha-glucosidase 0.014 0.1615 0.1804
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0047 0.0135
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.035 0.1156
Loa Loa (eye worm) hypothetical protein 0.0018 0.0085 0.0105
Echinococcus granulosus inositol monophosphatase 1 0.0074 0.0794 0.0885
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.1898 0.1896
Schistosoma mansoni lipoxygenase 0.0021 0.0123 0.0135
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0062 0.019
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0255 0.0283
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0006 0.0004
Schistosoma mansoni hypothetical protein 0.0065 0.0669 0.0746
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0147 0.0145
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.035 0.2291
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.1593 0.1591
Brugia malayi Doublecortin family protein 0.0021 0.0123 0.0382
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0204 0.2413 0.3083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0377 0.2473
Loa Loa (eye worm) hypothetical protein 0.0013 0.0027 0.0032
Echinococcus granulosus intermediate filament protein 0.0029 0.0219 0.0242
Loa Loa (eye worm) hypothetical protein 0.0038 0.0341 0.0433
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0676 0.21
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.1184 0.4243
Leishmania major hypothetical protein, conserved 0.0012 0.0006 0.0022
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0132 0.1518 1
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0119 0.015
Loa Loa (eye worm) dehydrogenase 0.0012 0.0006 0.0004
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0047 0.005
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.0676 0.4443
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0069 0.0215
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0085 0.0266
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0233 0.2783 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0499 0.3259
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0313 0.2052
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0237 0.03
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0062 0.0216
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0058 0.0593 0.0591
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0012 0.0006 0.0004
Echinococcus granulosus survival motor neuron protein 1 0.0264 0.316 0.3533
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0074 0.0794 0.2837
Loa Loa (eye worm) oxidoreductase 0.0012 0.0006 0.0004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Echinococcus multilocularis lamin 0.0029 0.0219 0.0217
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0161 0.0557
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0062 0.0395
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0006 0.0022
Loa Loa (eye worm) hypothetical protein 0.0039 0.035 0.0444
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.035 0.2291
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0255 0.0283
Leishmania major hypothetical protein, conserved 0.0012 0.0006 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0085 0.0105
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.003 0.018
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0012 0.0006 0.0003
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0132 0.1518 0.5451
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0161 0.1043
Trypanosoma brucei glucosidase, putative 0.0036 0.0313 0.2052
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.035 0.2291
Brugia malayi hypothetical protein 0.0264 0.316 0.9818
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.035 0.1087
Brugia malayi beta-lactamase family protein 0.0039 0.035 0.1087
Brugia malayi hypothetical protein 0.0051 0.0499 0.1549
Brugia malayi nuclear receptor NHR-67 0.0015 0.0047 0.0146
Loa Loa (eye worm) oxidoreductase 0.0012 0.0006 0.0004
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0006 0.0004
Loa Loa (eye worm) oxidoreductase 0.0012 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0466 0.3058
Loa Loa (eye worm) hypothetical protein 0.0139 0.1606 0.205
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0255 0.0283
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0047 0.005
Brugia malayi hypothetical protein 0.0012 0.0006 0.0018
Loa Loa (eye worm) hypothetical protein 0.0013 0.0027 0.0032
Plasmodium vivax hypothetical protein, conserved 0.0039 0.035 0.1249
Brugia malayi Retinol dehydrogenase 12 0.0012 0.0006 0.0018
Trichomonas vaginalis esterase, putative 0.0039 0.035 0.2291
Loa Loa (eye worm) hypothetical protein 0.0018 0.0083 0.0103
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0441 0.0561
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0441 0.1578
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.003 0.018
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0313 0.0348
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0073 0.0225
Schistosoma mansoni loxhd1 0.0021 0.0123 0.0135
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.035 0.0389
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0006 0.0004
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0255 0.0283
Echinococcus granulosus dnaJ subfamily B 0.0427 0.5208 0.5824
Schistosoma mansoni caspase-3 (C14 family) 0.035 0.4242 0.4743
Onchocerca volvulus 0.0019 0.0094 0.0287
Echinococcus granulosus GPCR family 2 0.0065 0.0669 0.0746
Brugia malayi steroid hormone receptor 0.0031 0.0255 0.0792
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.1332 0.4457
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Onchocerca volvulus 0.0015 0.0047 0.0135
Brugia malayi Bromodomain containing protein 0.0077 0.0821 0.2549
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.035 0.4242 0.4241
Loa Loa (eye worm) hypothetical protein 0.0031 0.0255 0.0323
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0075 0.0081
Echinococcus granulosus caspase 2 0.0256 0.3061 0.3422
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0499 0.3259
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0395
Toxoplasma gondii hypothetical protein 0.008 0.0868 0.3113
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0204 0.2413 0.7497
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0047 0.005
Echinococcus granulosus hypothetical protein 0.0012 0.0006 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0161 0.0557
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0255 0.0792
Plasmodium falciparum glutathione reductase 0.0016 0.0062 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.1518 1
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0006 0.0004
Leishmania major oxidoreductase-like protein 0.0012 0.0006 0.0022
Schistosoma mansoni coup transcription factor 0.0031 0.0255 0.0283
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0075 0.0081
Loa Loa (eye worm) oxidoreductase 0.0012 0.0006 0.0004
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0313 0.0311
Loa Loa (eye worm) hypothetical protein 0.0206 0.2442 0.312
Schistosoma mansoni hypothetical protein 0.0636 0.7821 0.8748
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0085 0.0297
Loa Loa (eye worm) hypothetical protein 0.0031 0.0255 0.0323
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0669 0.2078
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0255 0.0792
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0053 0.0065
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0006 0.0003
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.041 0.1466
Echinococcus multilocularis GPCR, family 2 0.0065 0.0669 0.0666
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Loa Loa (eye worm) hypothetical protein 0.0031 0.0255 0.0323
Brugia malayi dehydrogenases, short chain protein 9 0.0012 0.0006 0.0018
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0047 0.005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0377 0.1172
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0062 0.0375
Schistosoma mansoni importin beta-1 0.006 0.0607 0.0676
Schistosoma mansoni carbonyl reductase 0.0012 0.0006 0.0004
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0062 0.0204
Trypanosoma brucei metacaspase MCA3 0.0132 0.1518 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0086
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0132 0.1518 0.1696
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0658 0.0733
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.041 0.0408
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0255 0.0792
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0047 0.005
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0006 0.0003
Schistosoma mansoni hypothetical protein 0.0139 0.1606 0.1794
Schistosoma mansoni carbonyl reductase 0.0012 0.0006 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.1518 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.003 0.018
Leishmania major hypothetical protein, conserved 0.0012 0.0006 0.0022
Schistosoma mansoni hypothetical protein 0.0021 0.0123 0.0135
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0132 0.1518 0.4717
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0255 0.0792
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0153 0.1776 0.5951
Loa Loa (eye worm) hypothetical protein 0.0041 0.0377 0.0479
Schistosoma mansoni polycystin 1-related 0.0021 0.0123 0.0135
Schistosoma mansoni peptidase Clp (S14 family) 0.0233 0.2783 0.3111
Trypanosoma cruzi ISWI complex protein 0.0015 0.0053 0.0311
Trichomonas vaginalis inositol monophosphatase, putative 0.0074 0.0794 0.522
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0012 0.0006 0.0018
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0255 0.0253
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0255 0.0253
Echinococcus granulosus RUN 0.0021 0.0123 0.0135
Schistosoma mansoni cpg binding protein 0.003 0.0237 0.0262
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0313 0.2052
Plasmodium falciparum thioredoxin reductase 0.0016 0.0062 0.0216
Schistosoma mansoni rab6-interacting 0.0021 0.0123 0.0135
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0255 0.0283
Mycobacterium ulcerans hypothetical protein 0.0024 0.0161 0.0557
Schistosoma mansoni bromodomain containing protein 0.0065 0.0674 0.0751
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1593 0.178
Echinococcus multilocularis geminin 0.0725 0.894 0.894
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0047 0.005
Brugia malayi hypothetical protein 0.0017 0.0069 0.0215
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0313 0.2035
Brugia malayi N-terminal motif family protein 0.0206 0.2442 0.7588
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0233 0.2783 0.3111
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.0006 0.0038
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0153 0.1776 0.5951
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0047 0.0146
Brugia malayi beta-lactamase family protein 0.0039 0.035 0.1087
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0012 0.0006 0.0022
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0313 0.2052
Echinococcus granulosus caspase 0.035 0.4242 0.4743
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.035 0.1156
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0006 0.0022
Echinococcus multilocularis conserved hypothetical protein 0.0012 0.0006 0.0003
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0123 0.012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0086
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0255 0.0283
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0006 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0006 0.0012
Plasmodium falciparum steroid dehydrogenase, putative 0.0012 0.0006 0.0012
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0085 0.0297
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0062 0.0067
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0004
Mycobacterium tuberculosis Conserved protein 0.0039 0.035 0.1156
Schistosoma mansoni lipoxygenase 0.0058 0.0593 0.0661
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0006 0.0004
Loa Loa (eye worm) oxidoreductase 0.0012 0.0006 0.0004
Onchocerca volvulus 0.0031 0.0255 0.0816
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0255 0.0323
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.003 0.018
Onchocerca volvulus 0.0021 0.0123 0.0383
Entamoeba histolytica short chain dehydrogenase family protein 0.0012 0.0006 0.0038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0006 0.0018
Schistosoma mansoni hypothetical protein 0.0065 0.0669 0.0746
Schistosoma mansoni zinc finger protein 0.0015 0.0047 0.005
Echinococcus multilocularis caspase 8 0.0132 0.1518 0.1516
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0057
Echinococcus multilocularis tar DNA binding protein 0.0268 0.321 0.3208
Loa Loa (eye worm) hypothetical protein 0.0021 0.0123 0.0154
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0377 0.2473
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0255 0.0816
Loa Loa (eye worm) hypothetical protein 0.0204 0.2413 0.3083

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

24 literature references were collected for this gene.

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