Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.1195 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0486 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1195 | 0.124 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.1195 | 0.5 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.1195 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.37 | 0.2845 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.4303 | 0.5806 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.9266 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.1195 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.4303 | 0.5806 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0064 | 0.7374 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.1195 | 0.5 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0166 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3293 | 0.4427 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.1195 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.1195 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.4303 | 0.353 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.1195 | 0.5 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.1195 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3293 | 0.4427 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.1195 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.4446 | 0.4769 |
Brugia malayi | PHD-finger family protein | 0.0027 | 0.1401 | 0.0234 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.1195 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.1195 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0166 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0667 | 0.0774 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.1195 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.1195 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.4303 | 0.4613 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0667 | 0.0667 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0486 | 0.0592 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4118 | 0.4413 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.3712 | 0.3972 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.1195 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0995 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1195 | 0.124 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0158 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1195 | 0.124 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4303 | 0.5356 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.1195 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.1195 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0995 | 0.1188 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4303 | 0.5356 |
Onchocerca volvulus | 0.0026 | 0.1195 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.7988 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.4303 | 0.5806 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0166 | 0.139 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.1195 | 0.5 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0166 | 0.5 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0995 | 0.1287 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0064 | 0.7374 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4303 | 0.5356 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.4303 | 0.5806 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0486 | 0.0592 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.