Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0054 | 0.0057 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0043 | 0.0306 | 0.0303 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0043 | 0.0306 | 0.0487 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0176 | 0.0172 |
Leishmania major | trypanothione reductase | 0.0056 | 0.0442 | 0.4551 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0016 | 0.0022 | 0.0018 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0019 | 0.0054 | 0.0051 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0274 | 0.2769 | 1 |
Brugia malayi | ecdysone receptor | 0.0014 | 0.0003 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0022 | 0.0029 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0056 | 0.0442 | 0.1426 |
Loa Loa (eye worm) | beta-lactamase | 0.0043 | 0.0306 | 0.0482 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0019 | 0.0054 | 0.0057 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0031 | 0.0176 | 0.0279 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0047 | 0.0075 |
Trichomonas vaginalis | glutaminase, putative | 0.0302 | 0.307 | 1 |
Onchocerca volvulus | 0.0043 | 0.0306 | 0.1144 | |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0054 | 0.5 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0054 | 0.0057 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0306 | 0.0927 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0176 | 0.0279 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0249 | 0.2504 | 0.3975 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0203 | 0.287 |
Schistosoma mansoni | hypothetical protein | 0.0953 | 1 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0203 | 0.0199 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0019 | 0.005 | 0.0074 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.0294 | 0.0291 |
Giardia lamblia | Kinase, CMGC CLK | 0.0068 | 0.057 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0137 | 0.0134 |
Entamoeba histolytica | hypothetical protein | 0.01 | 0.0911 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0141 | 0.1351 | 0.4777 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0249 | 0.2504 | 0.3978 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0156 | 0.197 |
Echinococcus granulosus | dual specificity protein kinase clk2 | 0.0068 | 0.057 | 0.0567 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.01 | 0.0911 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0054 | 0.0057 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0294 | 0.0291 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.005 | 0.0079 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.01 | 0.0911 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0014 | 0.0003 | 0.0005 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0156 | 0.1237 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.01 | 0.0911 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0394 | 0.4046 | 0.6427 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0156 | 0.0243 |
Brugia malayi | beta-lactamase family protein | 0.0043 | 0.0306 | 0.0487 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0156 | 0.0243 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0016 | 0.0022 | 0.0018 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0394 | 0.4046 | 0.6427 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0031 | 0.0176 | 0.0172 |
Plasmodium falciparum | glutathione reductase | 0.0056 | 0.0442 | 0.7504 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.09 | 0.1426 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0068 | 0.057 | 0.0567 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0137 | 0.0134 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0054 | 0.0057 |
Plasmodium falciparum | protein serine/threonine kinase-1 | 0.0068 | 0.057 | 1 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0068 | 0.057 | 0.6046 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0054 | 0.0057 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0306 | 0.0835 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0137 | 0.0213 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0191 | 0.1888 | 0.3 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0043 | 0.0306 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0605 | 0.6294 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0043 | 0.0306 | 0.0927 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0.0306 | 0.0835 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0019 | 0.0054 | 0.0087 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0031 | 0.0176 | 0.0279 |
Trichomonas vaginalis | set domain proteins, putative | 0.0263 | 0.2653 | 0.8616 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0137 | 0.0213 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0176 | 0.0274 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0137 | 0.0134 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0306 | 0.0927 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0031 | 0.0176 | 0.0172 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0176 | 0.0274 |
Brugia malayi | Pre-SET motif family protein | 0.0231 | 0.2313 | 0.3675 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0137 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.09 | 0.1426 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0022 | 0.0034 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0031 | 0.0176 | 0.0172 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0306 | 0.0927 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0014 | 0.0003 | 0.0005 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0043 | 0.0306 | 0.0482 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0068 | 0.057 | 0.0567 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0043 | 0.0306 | 0.0303 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0137 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0022 | 0.0029 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0249 | 0.2504 | 0.2501 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0031 | 0.0176 | 0.0172 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0019 | 0.0054 | 0.0057 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0054 | 0.0057 |
Onchocerca volvulus | 0.0027 | 0.0137 | 0.0505 | |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0141 | 0.1351 | 0.4777 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0176 | 0.0274 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0127 | 0.1201 | 0.4222 |
Echinococcus multilocularis | dual specificity | 0.01 | 0.0911 | 0.0908 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0231 | 0.2313 | 0.3671 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0176 | 0.0172 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0056 | 0.0442 | 0.7504 |
Loa Loa (eye worm) | glutaminase | 0.0302 | 0.307 | 0.4876 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0019 | 0.0054 | 0.0016 |
Echinococcus granulosus | lamin | 0.0027 | 0.0137 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0176 | 0.0274 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0054 | 0.0057 |
Brugia malayi | nuclear hormone receptor | 0.0014 | 0.0003 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.0414 | 0.4255 | 0.4253 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0176 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0176 | 0.0274 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0176 | 0.0172 |
Mycobacterium ulcerans | hypothetical protein | 0.0043 | 0.0306 | 0.085 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0306 | 0.0835 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0249 | 0.2504 | 0.2501 |
Schistosoma mansoni | serine/threonine protein kinase | 0.01 | 0.0911 | 0.0908 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.0176 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0022 | 0.0029 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0249 | 0.2504 | 0.2501 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.1888 | 0.2997 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0022 | 0.0034 |
Brugia malayi | Thioredoxin reductase | 0.0056 | 0.0442 | 0.0702 |
Brugia malayi | nuclear receptor RXR | 0.0014 | 0.0003 | 0.0005 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0605 | 0.6294 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0176 | 0.0172 |
Entamoeba histolytica | protein kinase, putative | 0.01 | 0.0911 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.4046 | 0.4044 |
Entamoeba histolytica | protein kinase domain containing protein | 0.01 | 0.0911 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0953 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0449 | 0.463 | 0.4628 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0137 | 0.0213 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.4255 | 0.6758 |
Echinococcus granulosus | neuropeptide s receptor | 0.0449 | 0.463 | 0.4628 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0054 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.4046 | 0.4044 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0127 | 0.1201 | 0.4222 |
Plasmodium falciparum | thioredoxin reductase | 0.0056 | 0.0442 | 0.7504 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.005 | 0.0074 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0014 | 0.0003 | 0.0005 |
Echinococcus multilocularis | tar DNA binding protein | 0.0394 | 0.4046 | 0.4044 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0249 | 0.2504 | 0.2501 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0156 | 0.197 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0031 | 0.0176 | 0.0172 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0031 | 0.0176 | 0.0172 |
Brugia malayi | nuclear receptor NHR-88 | 0.0014 | 0.0003 | 0.0005 |
Brugia malayi | beta-lactamase family protein | 0.0043 | 0.0306 | 0.0487 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0176 | 0.0172 |
Echinococcus granulosus | hypothetical protein | 0.0067 | 0.0559 | 0.0556 |
Brugia malayi | Protein kinase domain containing protein | 0.01 | 0.0911 | 0.1448 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0176 | 0.0279 |
Loa Loa (eye worm) | TAR-binding protein | 0.0394 | 0.4046 | 0.6427 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0043 | 0.0306 | 0.0927 |
Trichomonas vaginalis | esterase, putative | 0.0043 | 0.0306 | 0.0835 |
Brugia malayi | glutaminase DH11.1 | 0.0302 | 0.307 | 0.4879 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0127 | 0.1201 | 0.4222 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0031 | 0.0176 | 0.0274 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0031 | 0.0176 | 0.0172 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0003 | 0.0005 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0176 | 0.0274 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0016 | 0.0022 | 0.0018 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0449 | 0.463 | 0.4628 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0605 | 0.6294 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0176 | 0.0172 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.4046 | 0.4044 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0306 | 0.2979 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0203 | 0.0199 |
Brugia malayi | nuclear receptor RXR | 0.0016 | 0.0022 | 0.0034 |
Echinococcus granulosus | FTZ F1 alpha | 0.0031 | 0.0176 | 0.0172 |
Mycobacterium tuberculosis | Probable reductase | 0.0127 | 0.1201 | 0.4222 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0559 | 0.0884 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0306 | 0.0482 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0019 | 0.0054 | 0.0051 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.0176 | 0.0172 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0203 | 0.0199 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0449 | 0.463 | 0.4628 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.01 | 0.0911 | 0.1443 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0176 | 0.0172 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0068 | 0.057 | 0.6046 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.01 | 0.0911 | 1 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0068 | 0.057 | 0.6046 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0031 | 0.0176 | 0.0172 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0191 | 0.1888 | 0.1886 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0306 | 0.2979 |
Trypanosoma brucei | kinetoplastid kinetochore protein 10 | 0.0068 | 0.057 | 0.6046 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0176 | 0.0279 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0056 | 0.0442 | 0.4551 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0043 | 0.0306 | 0.0927 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0137 | 0.0218 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0176 | 0.0172 |
Brugia malayi | steroid hormone receptor | 0.0031 | 0.0176 | 0.0279 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0414 | 0.4255 | 0.676 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0176 | 0.0274 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.4046 | 0.4044 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0176 | 0.0172 |
Brugia malayi | Protein kinase domain containing protein | 0.0068 | 0.057 | 0.0906 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0031 | 0.0176 | 0.0651 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0191 | 0.1888 | 0.1886 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0022 | 0.0034 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0191 | 0.1888 | 0.1886 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0054 | 0.0057 |
Brugia malayi | TAR-binding protein | 0.0394 | 0.4046 | 0.6429 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0054 | 0.0057 |
Leishmania major | hypothetical protein, conserved | 0.0043 | 0.0306 | 0.2979 |
Brugia malayi | nuclear receptor NHR-67 | 0.0014 | 0.0003 | 0.0005 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.0176 | 0.0279 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0031 | 0.0176 | 0.0651 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0043 | 0.0306 | 0.0927 |
Mycobacterium ulcerans | glutaminase | 0.0302 | 0.307 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.0176 | 0.0279 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.1888 | 0.1886 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0031 | 0.0176 | 0.0172 |
Mycobacterium ulcerans | lipase LipD | 0.0043 | 0.0306 | 0.085 |
Loa Loa (eye worm) | CMGC/CLK protein kinase | 0.0068 | 0.057 | 0.0902 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.1888 | 0.1886 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0068 | 0.057 | 0.6046 |
Onchocerca volvulus | 0.0031 | 0.0176 | 0.0651 | |
Onchocerca volvulus | 0.0033 | 0.0203 | 0.0752 | |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0137 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0176 | 0.0274 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0014 | 0.0003 | 0.0005 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0203 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0022 | 0.0029 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0019 | 0.0054 | 0.0016 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0249 | 0.2504 | 0.2501 |
Toxoplasma gondii | cell-cycle-associated protein kinase CLK, putative | 0.0068 | 0.057 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0054 | 0.0057 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0043 | 0.0306 | 0.0303 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0019 | 0.0054 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0394 | 0.4046 | 0.6429 |
Onchocerca volvulus | 0.0027 | 0.0137 | 0.0505 | |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0156 | 0.1237 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0022 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0176 | 0.0274 |
Onchocerca volvulus | 0.0043 | 0.0306 | 0.1144 | |
Onchocerca volvulus | 0.0263 | 0.2653 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0249 | 0.2504 | 0.2501 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0031 | 0.0176 | 0.0651 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0043 | 0.0306 | 0.0303 |
Echinococcus multilocularis | geminin | 0.0953 | 1 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0043 | 0.0306 | 0.0927 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.019 | 0.0186 |
Entamoeba histolytica | protein kinase, putative | 0.01 | 0.0911 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0203 | 0.0199 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0127 | 0.1201 | 0.8557 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0141 | 0.1351 | 0.4777 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0176 | 0.0274 |
Leishmania major | protein kinase, putative | 0.0068 | 0.057 | 0.6046 |
Plasmodium vivax | glutathione reductase, putative | 0.0056 | 0.0442 | 0.7504 |
Schistosoma mansoni | coup transcription factor | 0.0031 | 0.0176 | 0.0172 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.005 | 0.0074 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0294 | 0.0467 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0176 | 0.0279 |
Onchocerca volvulus | 0.0043 | 0.0306 | 0.1144 | |
Plasmodium vivax | serine/threonine kinase-1, putative | 0.0068 | 0.057 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0014 | 0.0003 | 0.0005 |
Mycobacterium ulcerans | beta-lactamase | 0.0043 | 0.0306 | 0.085 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0056 | 0.0442 | 0.0697 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0176 | 0.0274 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0203 | 0.287 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0306 | 0.0482 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0031 | 0.0176 | 0.0279 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0203 | 0.0199 |
Schistosoma mansoni | lamin | 0.0027 | 0.0137 | 0.0134 |
Echinococcus multilocularis | GPCR, family 2 | 0.0191 | 0.1888 | 0.1886 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0019 | 0.0054 | 0.0051 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0019 | 0.0054 | 0.0057 |
Echinococcus multilocularis | dual specificity protein kinase clk2 | 0.0068 | 0.057 | 0.0567 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0176 | 0.0279 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0176 | 0.0279 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0176 | 0.0279 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0019 | 0.0054 | 0.0057 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0019 | 0.0054 | 0.0057 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0068 | 0.057 | 0.1711 |
Toxoplasma gondii | thioredoxin reductase | 0.0056 | 0.0442 | 0.7504 |
Loa Loa (eye worm) | glutaminase 2 | 0.0302 | 0.307 | 0.4876 |
Treponema pallidum | NADH oxidase | 0.0019 | 0.0054 | 0.5 |
Brugia malayi | RNA binding protein | 0.0394 | 0.4046 | 0.6429 |
Brugia malayi | conserved hypotetical protein | 0.0014 | 0.0003 | 0.0005 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.0294 | 0.0291 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0.0306 | 0.0835 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0031 | 0.0176 | 0.0172 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0203 | 0.0199 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0127 | 0.1201 | 0.4222 |
Echinococcus granulosus | dual specificity | 0.01 | 0.0911 | 0.0908 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0203 | 0.0317 |
Echinococcus granulosus | tar DNA binding protein | 0.0394 | 0.4046 | 0.4044 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.1888 | 0.1886 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0191 | 0.1888 | 0.1886 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0176 | 0.0274 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0.0306 | 0.4879 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0031 | 0.0176 | 0.0172 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0031 | 0.0176 | 0.0172 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0031 | 0.0176 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0306 | 0.0482 |
Trypanosoma brucei | kinetoplastid kinetochore protein 19 | 0.0068 | 0.057 | 0.6046 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0306 | 0.0482 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0043 | 0.0306 | 0.0927 |
Toxoplasma gondii | ABC1 family protein | 0.0043 | 0.0306 | 0.4879 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0191 | 0.1888 | 0.2997 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0019 | 0.0054 | 0.0016 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0031 | 0.0176 | 0.0172 |
Echinococcus granulosus | GPCR family 2 | 0.0191 | 0.1888 | 0.1886 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0132 | 0.0205 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0249 | 0.2504 | 0.2501 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0137 | 0.0134 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0156 | 0.197 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0191 | 0.1888 | 0.3 |
Schistosoma mansoni | glutaminase | 0.0302 | 0.307 | 0.3068 |
Brugia malayi | beta-lactamase | 0.0043 | 0.0306 | 0.0487 |
Loa Loa (eye worm) | glutathione reductase | 0.0056 | 0.0442 | 0.0697 |
Trypanosoma brucei | trypanothione reductase | 0.0056 | 0.0442 | 0.4551 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0031 | 0.0176 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0306 | 0.0482 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0176 | 0.0279 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0176 | 0.0279 |
Schistosoma mansoni | lamin | 0.0027 | 0.0137 | 0.0134 |
Brugia malayi | glutathione reductase | 0.0056 | 0.0442 | 0.0702 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0056 | 0.0442 | 0.0439 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0031 | 0.0176 | 0.0172 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0056 | 0.0442 | 0.0439 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0141 | 0.1351 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0306 | 0.0835 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0156 | 0.1237 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0043 | 0.0306 | 0.2979 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0156 | 0.1237 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.4046 | 0.4044 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0016 | 0.0022 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0176 | 0.0274 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0203 | 0.0322 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0031 | 0.0176 | 0.0274 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0054 | 0.0057 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0176 | 0.0279 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0176 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0022 | 0.0029 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0016 | 0.0022 | 0.0029 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0043 | 0.0306 | 0.085 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0003 | 0.0005 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0176 | 0.0172 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0605 | 0.6294 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0948 | 0.9943 | 0.9943 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0031 | 0.0176 | 0.0279 |
Echinococcus multilocularis | 0.0067 | 0.0559 | 0.0556 | |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0043 | 0.0306 | 0.0927 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0156 | 0.197 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0014 | 0.0003 | 0.0005 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0156 | 0.0248 |
Leishmania major | protein kinase, putative | 0.0068 | 0.057 | 0.6046 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.005 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.1888 | 0.1886 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0176 | 0.0274 |
Brugia malayi | ecdysteroid receptor | 0.0031 | 0.0176 | 0.0279 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0054 | 0.0057 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.0176 | 0.0172 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0127 | 0.1201 | 0.4222 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0156 | 0.0248 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.0294 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0306 | 0.0482 |
Brugia malayi | tailless protein | 0.0014 | 0.0003 | 0.0005 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0003 | 0.0005 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.