Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0333 | 0.1122 | 0.2069 |
Onchocerca volvulus | 0.0034 | 0.0029 | 0.0032 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1471 | 0.5281 | 0.5275 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.0135 | 0.0188 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0333 | 0.1122 | 0.1111 |
Echinococcus granulosus | cathepsin b | 0.2762 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1471 | 0.5281 | 0.5275 |
Leishmania major | cathepsin L-like protease | 0.1471 | 0.5281 | 1 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.1194 | 0.427 | 0.4263 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0333 | 0.1122 | 0.2106 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0036 | 0.0029 |
Entamoeba histolytica | cysteine protease, putative | 0.0333 | 0.1122 | 0.2069 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0461 | 0.1592 | 0.1592 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Onchocerca volvulus | 0.023 | 0.0746 | 0.1394 | |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0333 | 0.1122 | 0.2106 |
Giardia lamblia | Cathepsin L precursor | 0.0333 | 0.1122 | 0.2643 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0036 | 0.0036 |
Leishmania major | cathepsin L-like protease | 0.1471 | 0.5281 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0789 | 0.279 | 0.2782 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0056 | 0.0112 | 0.01 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1471 | 0.5281 | 0.5277 |
Echinococcus granulosus | cathepsin L | 0.0333 | 0.1122 | 0.1115 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0794 | 0.2808 | 0.2782 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1471 | 0.5281 | 0.5264 |
Loa Loa (eye worm) | hypothetical protein | 0.1009 | 0.3595 | 0.3595 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Echinococcus multilocularis | geminin | 0.0175 | 0.0546 | 0.0535 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Echinococcus multilocularis | cathepsin b | 0.2762 | 1 | 1 |
Echinococcus multilocularis | calpain family protein 1, d | 0.004 | 0.0051 | 0.0039 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0794 | 0.2808 | 0.2782 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0333 | 0.1122 | 0.1122 |
Toxoplasma gondii | cathepsin CPC2 | 0.0333 | 0.1122 | 0.2106 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0333 | 0.1122 | 0.1917 |
Brugia malayi | cathepsin L precursor | 0.0333 | 0.1122 | 0.1122 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0333 | 0.1122 | 0.1917 |
Entamoeba histolytica | cysteine protease, putative | 0.0333 | 0.1122 | 0.2069 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0794 | 0.2808 | 0.2799 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0036 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0794 | 0.2808 | 0.5285 |
Giardia lamblia | Cathepsin B precursor | 0.1084 | 0.3868 | 1 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0333 | 0.1122 | 0.2106 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0036 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0333 | 0.1122 | 0.1122 |
Giardia lamblia | Cathepsin B precursor | 0.0333 | 0.1122 | 0.2643 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.0546 | 0.0535 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0036 | 0.0492 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0794 | 0.2808 | 0.2799 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0036 | 0.0492 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0333 | 0.1122 | 0.1917 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0036 | 0.0492 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1471 | 0.5281 | 0.5281 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1471 | 0.5281 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0794 | 0.2808 | 0.2799 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0333 | 0.1122 | 0.2106 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1471 | 0.5281 | 1 |
Leishmania major | cathepsin L-like protease | 0.1471 | 0.5281 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0333 | 0.1122 | 0.2643 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1122 | 0.1122 |
Entamoeba histolytica | cysteine protease, putative | 0.0333 | 0.1122 | 0.2069 |
Onchocerca volvulus | Cathepsin L homolog | 0.1471 | 0.5281 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0333 | 0.1122 | 0.1089 |
Leishmania major | cathepsin L-like protease | 0.1471 | 0.5281 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0461 | 0.1592 | 0.1592 |
Onchocerca volvulus | 0.1471 | 0.5281 | 1 | |
Giardia lamblia | Cysteine protease | 0.0333 | 0.1122 | 0.2643 |
Brugia malayi | Cathepsin L-like precursor | 0.1471 | 0.5281 | 0.5281 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0794 | 0.2808 | 0.5284 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0333 | 0.1122 | 0.2643 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0333 | 0.1122 | 0.1111 |
Trichomonas vaginalis | set domain proteins, putative | 0.023 | 0.0746 | 0.1354 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0036 | 1 |
Leishmania major | cathepsin L-like protease | 0.1471 | 0.5281 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0794 | 0.2808 | 0.5285 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1122 | 0.1122 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0036 | 0.0036 |
Entamoeba histolytica | prefoldin subunit 6, putative | 0.0063 | 0.0135 | 0.0188 |
Echinococcus granulosus | cathepsin b | 0.2762 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1471 | 0.5281 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0036 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0333 | 0.1122 | 0.2643 |
Trypanosoma cruzi | prefoldin subunit, putative | 0.0063 | 0.0135 | 0.0099 |
Loa Loa (eye worm) | calpain family protein 1 | 0.004 | 0.0051 | 0.0051 |
Loa Loa (eye worm) | fibroinase | 0.1471 | 0.5281 | 0.5281 |
Echinococcus multilocularis | cysteine protease | 0.1471 | 0.5281 | 0.5275 |
Loa Loa (eye worm) | hypothetical protein | 0.0461 | 0.1592 | 0.1592 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1471 | 0.5281 | 0.5281 |
Onchocerca volvulus | Cathepsin F homolog | 0.1471 | 0.5281 | 1 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0333 | 0.1122 | 0.2643 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0333 | 0.1122 | 0.1917 |
Plasmodium vivax | vivapain-3 | 0.0794 | 0.2808 | 0.5307 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1471 | 0.5281 | 1 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0333 | 0.1122 | 0.2069 |
Toxoplasma gondii | cathepsin CPL | 0.1471 | 0.5281 | 1 |
Brugia malayi | KE2 family protein | 0.0063 | 0.0135 | 0.0135 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1471 | 0.5281 | 0.5264 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0461 | 0.1592 | 0.1592 |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0333 | 0.1122 | 0.1111 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0036 | 0.0025 |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0333 | 0.1122 | 0.2069 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1471 | 0.5281 | 0.5275 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0135 | 0.0135 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1471 | 0.5281 | 0.5277 |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Giardia lamblia | Cysteine protease | 0.0333 | 0.1122 | 0.2643 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0333 | 0.1122 | 0.1122 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.0546 | 0.0535 |
Toxoplasma gondii | cathepsin B | 0.1084 | 0.3868 | 0.7318 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0054 | 0.0103 | 0.0103 |
Brugia malayi | Cathepsin L-like precursor | 0.1471 | 0.5281 | 0.5281 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0333 | 0.1122 | 0.1111 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0029 | 0.0029 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Giardia lamblia | Hypothetical protein | 0.0333 | 0.1122 | 0.2643 |
Giardia lamblia | Hypothetical protein | 0.0333 | 0.1122 | 0.2643 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0036 | 0.0036 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Giardia lamblia | Cysteine protease | 0.0333 | 0.1122 | 0.2643 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0794 | 0.2808 | 0.5285 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1471 | 0.5281 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0333 | 0.1122 | 0.1111 |
Trypanosoma cruzi | prefoldin subunit, putative | 0.0063 | 0.0135 | 0.0099 |
Brugia malayi | cathepsin L-like precursor | 0.1009 | 0.3595 | 0.3595 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0333 | 0.1122 | 0.1111 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0794 | 0.2808 | 0.5285 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0333 | 0.1122 | 0.1111 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0056 | 0.0112 | 0.01 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0036 | 0.0492 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0228 | 0.074 | 1 |
Brugia malayi | fibroinase precursor | 0.0333 | 0.1122 | 0.1122 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1009 | 0.3595 | 0.3587 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0333 | 0.1122 | 0.2106 |
Entamoeba histolytica | hypothetical protein | 0.0333 | 0.1122 | 0.2069 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2762 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0794 | 0.2808 | 0.5194 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0103 | 0.0103 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0333 | 0.1122 | 0.1917 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0081 | 0.0081 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Echinococcus granulosus | geminin | 0.0175 | 0.0546 | 0.0538 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0333 | 0.1122 | 0.1917 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0036 |
Echinococcus granulosus | cysteine protease | 0.0794 | 0.2808 | 0.2802 |
Onchocerca volvulus | 0.1471 | 0.5281 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0333 | 0.1122 | 0.1111 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1471 | 0.5281 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0461 | 0.1592 | 0.1592 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0333 | 0.1122 | 0.1111 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0036 | 0.0028 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0333 | 0.1122 | 0.2106 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0036 | 0.0047 |
Trypanosoma brucei | prefoldin subunit, putative | 0.0063 | 0.0135 | 0.0188 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0333 | 0.1122 | 0.1917 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0333 | 0.1122 | 0.1111 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0047 | 0.0077 | 0.0124 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0036 | 0.0036 |
Toxoplasma gondii | cathepsin CPC1 | 0.0333 | 0.1122 | 0.2106 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0333 | 0.1122 | 0.2106 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1471 | 0.5281 | 0.5275 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0051 | 0.0051 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0036 | 0.0025 |
Echinococcus granulosus | cathepsin l1 | 0.1009 | 0.3595 | 0.359 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1009 | 0.3595 | 0.6785 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.1471 | 0.5281 | 1 | |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0036 | 0.0492 |
Onchocerca volvulus | 0.1471 | 0.5281 | 1 | |
Loa Loa (eye worm) | ctsf protein | 0.1471 | 0.5281 | 0.5281 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0036 | 0.0492 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1471 | 0.5281 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1471 | 0.5281 | 0.5275 |
Toxoplasma gondii | prefoldin subunit 6, putative | 0.0063 | 0.0135 | 0.0234 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0333 | 0.1122 | 0.2069 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0333 | 0.1122 | 0.1122 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0333 | 0.1122 | 0.2106 |
Loa Loa (eye worm) | matrixin family protein | 0.0051 | 0.0093 | 0.0093 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0036 | 0.0492 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0794 | 0.2808 | 0.2799 |
Leishmania major | cysteine peptidase A (CPA) | 0.1471 | 0.5281 | 1 |
Plasmodium vivax | vivapain-2 | 0.1471 | 0.5281 | 1 |
Schistosoma mansoni | cathepsin s | 0.0461 | 0.1592 | 0.1582 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0333 | 0.1122 | 0.2643 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0333 | 0.1122 | 0.1917 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0036 | 0.0492 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1471 | 0.5281 | 0.5275 |
Entamoeba histolytica | cysteine protease, putative | 0.0333 | 0.1122 | 0.2069 |
Leishmania major | cathepsin L-like protease | 0.1471 | 0.5281 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1471 | 0.5281 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1009 | 0.3595 | 0.6785 |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Brugia malayi | Cathepsin L-like precursor | 0.1471 | 0.5281 | 0.5281 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.1471 | 0.5281 | 0.5277 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0794 | 0.2808 | 0.2802 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0333 | 0.1122 | 0.1122 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0333 | 0.1122 | 0.1122 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1471 | 0.5281 | 0.5281 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1471 | 0.5281 | 0.5264 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1471 | 0.5281 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0794 | 0.2808 | 0.2808 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1122 | 0.1122 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0012 | 0.0012 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0794 | 0.2808 | 0.5284 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0036 | 0.0492 |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0333 | 0.1122 | 0.1122 |
Brugia malayi | Cathepsin L-like precursor | 0.1009 | 0.3595 | 0.3595 |
Loa Loa (eye worm) | cathepsin B | 0.1084 | 0.3868 | 0.3868 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0056 | 0.0112 | 0.01 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.1084 | 0.3868 | 0.7305 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0036 |
Echinococcus granulosus | cathepsin L | 0.0794 | 0.2808 | 0.2802 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0333 | 0.1122 | 0.1122 |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0333 | 0.1122 | 0.2643 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1122 | 0.1122 |
Onchocerca volvulus | 0.1471 | 0.5281 | 1 | |
Brugia malayi | Hemopexin family protein | 0.003 | 0.0015 | 0.0015 |
Giardia lamblia | Cathepsin L precursor | 0.0333 | 0.1122 | 0.2643 |
Brugia malayi | calpain family protein 1 | 0.0054 | 0.0103 | 0.0103 |
Giardia lamblia | Cathepsin L-like protease | 0.0333 | 0.1122 | 0.2643 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1471 | 0.5281 | 1 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0333 | 0.1122 | 0.1111 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0036 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0036 | 0.0492 |
Giardia lamblia | Encystation-specific protease | 0.0333 | 0.1122 | 0.2643 |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0012 | 0.0004 |
Entamoeba histolytica | cysteine protease, putative | 0.0333 | 0.1122 | 0.2069 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0036 | 0.0025 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0333 | 0.1122 | 0.2106 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0333 | 0.1122 | 0.1917 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0333 | 0.1122 | 0.1917 |
Loa Loa (eye worm) | matrixin family protein | 0.0047 | 0.0077 | 0.0077 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0135 | 0.0123 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1471 | 0.5281 | 0.5275 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1009 | 0.3595 | 0.3595 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1009 | 0.3595 | 0.6785 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.1194 | 0.427 | 0.4265 |
Brugia malayi | Cathepsin L-like precursor | 0.1471 | 0.5281 | 0.5281 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Echinococcus granulosus | prefoldin subunit 6 | 0.0063 | 0.0135 | 0.0127 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1471 | 0.5281 | 1 |
Plasmodium vivax | vivapain-2 | 0.1471 | 0.5281 | 1 |
Giardia lamblia | Cysteine protease | 0.0333 | 0.1122 | 0.2643 |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Plasmodium vivax | unspecified product | 0.0794 | 0.2808 | 0.5307 |
Echinococcus multilocularis | prefoldin subunit 6 | 0.0063 | 0.0135 | 0.0123 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0036 | 0.0025 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1471 | 0.5281 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0056 | 0.0112 | 0.0104 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0036 | 0.0047 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0333 | 0.1122 | 0.2643 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0333 | 0.1122 | 0.1089 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0794 | 0.2808 | 0.5285 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1471 | 0.5281 | 1 |
Onchocerca volvulus | 0.1471 | 0.5281 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Loa Loa (eye worm) | hypothetical protein | 0.2762 | 1 | 1 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0036 | 0.0036 |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Giardia lamblia | Cathepsin B precursor | 0.0333 | 0.1122 | 0.2643 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1122 | 0.1122 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0461 | 0.1592 | 0.1561 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0012 | 0.0012 |
Brugia malayi | Pre-SET motif family protein | 0.0202 | 0.0644 | 0.0644 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Plasmodium vivax | unspecified product | 0.0333 | 0.1122 | 0.2106 |
Onchocerca volvulus | 0.1009 | 0.3595 | 0.68 | |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2762 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1084 | 0.3868 | 0.7305 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1471 | 0.5281 | 0.5264 |
Onchocerca volvulus | 0.0036 | 0.0036 | 0.0047 | |
Brugia malayi | Cathepsin L-like precursor | 0.1471 | 0.5281 | 0.5281 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0333 | 0.1122 | 0.1917 |
Loa Loa (eye worm) | hypothetical protein | 0.0461 | 0.1592 | 0.1592 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0794 | 0.2808 | 0.5284 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0794 | 0.2808 | 0.2782 |
Onchocerca volvulus | Cathepsin L homolog | 0.1471 | 0.5281 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0794 | 0.2808 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0036 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Onchocerca volvulus | 0.0333 | 0.1122 | 0.2106 | |
Brugia malayi | Cathepsin L-like precursor | 0.1471 | 0.5281 | 0.5281 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0036 | 0.0025 |
Giardia lamblia | Cathepsin B precursor | 0.0333 | 0.1122 | 0.2643 |
Loa Loa (eye worm) | hypothetical protein | 0.1471 | 0.5281 | 0.5281 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1471 | 0.5281 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2762 | 1 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0054 | 0.0103 | 0.0091 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0333 | 0.1122 | 0.2106 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.1009 | 0.3595 | 0.3595 |
Leishmania major | cathepsin L-like protease | 0.1471 | 0.5281 | 1 |
Brugia malayi | Matrixin family protein | 0.0051 | 0.0093 | 0.0093 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0333 | 0.1122 | 0.1917 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1084 | 0.3868 | 0.3845 |
Brugia malayi | calpain family protein 1 | 0.0054 | 0.0103 | 0.0103 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1471 | 0.5281 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0036 | 0.0036 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0461 | 0.1592 | 0.1561 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.1009 | 0.3595 | 0.3571 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0036 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1009 | 0.3595 | 0.3595 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2762 | 1 | 1 |
Onchocerca volvulus | 0.1471 | 0.5281 | 1 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0333 | 0.1122 | 0.2106 |
Plasmodium vivax | unspecified product | 0.0461 | 0.1592 | 0.2999 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0333 | 0.1122 | 0.2106 |
Entamoeba histolytica | cysteine protease, putative | 0.0794 | 0.2808 | 0.5285 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0077 | 0.0187 | 0.0175 |
Onchocerca volvulus | 0.0036 | 0.0036 | 0.0047 | |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0036 | 1 |
Schistosoma mansoni | cathepsin C | 0.0333 | 0.1122 | 0.1111 |
Loa Loa (eye worm) | cysteine protease | 0.1471 | 0.5281 | 0.5281 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1471 | 0.5281 | 0.5264 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0794 | 0.2808 | 0.5285 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0333 | 0.1122 | 0.2106 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0333 | 0.1122 | 0.1122 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0036 | 0.0025 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0333 | 0.1122 | 0.2643 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2762 | 1 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0461 | 0.1592 | 0.1592 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1084 | 0.3868 | 0.386 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0794 | 0.2808 | 0.2808 |
Leishmania major | cathepsin L-like protease | 0.1471 | 0.5281 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0333 | 0.1122 | 0.2106 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0202 | 0.0644 | 0.0644 |
Plasmodium vivax | prefoldin subunit 6, putative | 0.0063 | 0.0135 | 0.0234 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0333 | 0.1122 | 0.1122 |
Echinococcus granulosus | calpain A | 0.0056 | 0.0112 | 0.0104 |
Entamoeba histolytica | cysteine protease, putative | 0.0333 | 0.1122 | 0.2069 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1471 | 0.5281 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.1084 | 0.3868 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0333 | 0.1122 | 0.2643 |
Loa Loa (eye worm) | hypothetical protein | 0.1009 | 0.3595 | 0.3595 |
Plasmodium vivax | vivapain-1 | 0.0794 | 0.2808 | 0.5307 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0333 | 0.1122 | 0.1122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1122 | 0.1122 |
Leishmania major | prefoldin subunit, putative | 0.0063 | 0.0135 | 0.0188 |
Echinococcus multilocularis | cathepsin b | 0.2762 | 1 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0036 | 1 |
Onchocerca volvulus | Matrilysin homolog | 0.0047 | 0.0077 | 0.0124 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0333 | 0.1122 | 0.2069 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1471 | 0.5281 | 1 |
Giardia lamblia | Cathepsin L-like protease | 0.0333 | 0.1122 | 0.2643 |
Onchocerca volvulus | 0.003 | 0.0015 | 0.0007 | |
Trypanosoma cruzi | cysteine protease, putative | 0.0794 | 0.2808 | 0.2782 |
Giardia lamblia | Cathepsin B precursor | 0.0333 | 0.1122 | 0.2643 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0077 | 0.0187 | 0.0179 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1471 | 0.5281 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0794 | 0.2808 | 0.5284 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0015 | 0.0004 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0333 | 0.1122 | 0.1111 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0036 | 1 |
Echinococcus multilocularis | calpain A | 0.0056 | 0.0112 | 0.01 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0036 | 0.0036 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1084 | 0.3868 | 0.7305 |
Giardia lamblia | Cathepsin B precursor | 0.1084 | 0.3868 | 1 |
Onchocerca volvulus | 0.0036 | 0.0036 | 0.0047 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 200 nM | Inhibitory activity against squalene synthase in rat liver squalene synthase (RLSS) enzyme assay | ChEMBL. | No reference |
Activity (binding) | = 200 nM | Inhibitory activity against squalene synthase in rat liver squalene synthase (RLSS) enzyme assay | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.