Detailed information for compound 582760

Basic information

Technical information
  • TDR Targets ID: 582760
  • Name: arsane
  • MW: 77.9454 | Formula: AsH3
  • H donors: 0 H acceptors: 0 LogP: 0 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1


Substructure search Similarity search

Network

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Synonyms

  • arsine
  • $l^{1}-arsane
  • $l^{1}-arsine
  • Arsenic trihydride
  • CHEBI:33104
  • (AsH)(2.)
  • AsH(2.)
  • Ash
  • arsanediyl (triplet)
  • arsenic monohydride
  • hydridoarsenic(2.) (triplet)
  • Arsenwasserstoff
  • AsH3
  • CHEBI:47217
  • [AsH3]
  • trihydridoarsenic

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0535 0.0351
Brugia malayi TAR-binding protein 0.0063 0.2968 0.4502
Brugia malayi AKH receptor 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0048 0.2237 0.3393
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0005 0.0058 0.0087
Schistosoma mansoni biogenic amine receptor 0.0005 0.0058 0.0067
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0058 0.0067
Loa Loa (eye worm) hypothetical protein 0.0036 0.1628 0.2469
Loa Loa (eye worm) hypothetical protein 0.0014 0.0535 0.0811
Brugia malayi G protein-coupled receptor F59B2.13 0.0005 0.0058 0.0087
Onchocerca volvulus 0.0056 0.2625 0.4297
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.2209 0.2209
Echinococcus multilocularis neuropeptides capa receptor 0.0005 0.0058 0.0058
Echinococcus granulosus geminin 0.0176 0.8648 0.8648
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0058 0.0067
Echinococcus granulosus neuropeptide Y receptor 0.0005 0.0058 0.0058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.153 0.3905
Echinococcus multilocularis neuropeptide FF receptor 2 0.0005 0.0058 0.0058
Brugia malayi Matrixin family protein 0.0056 0.2625 0.3982
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0005 0.0058 0.0067
Echinococcus multilocularis transient receptor potential cation channel 0.0003 0.000000082652 0.000000082652
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0535 0.0535
Brugia malayi hypothetical protein 0.0005 0.0058 0.0087
Onchocerca volvulus Matrilysin homolog 0.0056 0.2625 0.4297
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Echinococcus granulosus neuropeptide Y receptor 0.0005 0.0058 0.0058
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.1628 0.4048
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0535 0.0351
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0005 0.0058 0.0058
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0005 0.0058 0.0067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Echinococcus multilocularis neuropeptide Y receptor 0.0005 0.0058 0.0058
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.2209 0.335
Brugia malayi putative neuropeptide receptor NPR1 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Schistosoma mansoni biogenic amine receptor 0.0005 0.0058 0.0067
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.2237 0.6433
Echinococcus multilocularis serotonin receptor 0.0005 0.0058 0.0058
Echinococcus multilocularis transient receptor potential cation channel 0.0003 0.000000082652 0.000000082652
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0058 0.0067
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0535 0.5
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0068 0.3235 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0005 0.0058 0.0058
Echinococcus multilocularis neuropeptide receptor 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0005 0.0058 0.0087
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.153 0.3905
Brugia malayi G-protein coupled receptor 0.0005 0.0058 0.0087
Brugia malayi hypothetical protein 0.0005 0.0058 0.0087
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.2237 0.6304
Echinococcus granulosus tar DNA binding protein 0.0063 0.2968 0.2968
Brugia malayi Matrixin family protein 0.0135 0.6592 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.2237 1
Loa Loa (eye worm) G-protein coupled receptor 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Brugia malayi G protein-coupled receptor 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0036 0.1628 0.2469
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0058 0.0067
Schistosoma mansoni biogenic amine (5HT) receptor 0.0005 0.0058 0.0067
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.2209 0.2554
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Echinococcus multilocularis neuropeptides capa receptor 0.0005 0.0058 0.0058
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.2209 0.2209
Loa Loa (eye worm) matrixin family protein 0.0124 0.6033 0.9151
Schistosoma mansoni amine GPCR 0.0005 0.0058 0.0067
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0063 0.2968 0.3432
Brugia malayi hypothetical protein 0.0005 0.0058 0.0087
Schistosoma mansoni hypothetical protein 0.0005 0.0058 0.0067
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Brugia malayi AMP-binding enzyme family protein 0.0048 0.2237 0.3393
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0005 0.0058 0.0058
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0005 0.0058 0.0067
Brugia malayi Serotonin receptor 0.0005 0.0058 0.0087
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.2237 1
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0535 0.0351
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0535 0.0811
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0005 0.0058 0.0067
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0005 0.0058 0.0058
Echinococcus granulosus neuropeptides capa receptor 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Brugia malayi larval opioid receptor 0.0005 0.0058 0.0087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.2209 0.2554
Echinococcus granulosus sex peptide receptor 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0048 0.2237 0.3393
Echinococcus granulosus dro:myosuppressin receptor 0.0005 0.0058 0.0058
Echinococcus multilocularis sex peptide receptor 0.0005 0.0058 0.0058
Brugia malayi hypothetical protein 0.0005 0.0058 0.0087
Echinococcus multilocularis G-protein coupled receptor, putative 0.0005 0.0058 0.0058
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0005 0.0058 0.0067
Schistosoma mansoni tar DNA-binding protein 0.0063 0.2968 0.3432
Echinococcus multilocularis neuropeptide receptor 0.0005 0.0058 0.0058
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0535 0.0351
Loa Loa (eye worm) hypothetical protein 0.0056 0.2625 0.3982
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0005 0.0058 0.0058
Echinococcus granulosus orexin receptor type 2 0.0005 0.0058 0.0058
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0535 0.5
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Brugia malayi Dopamine receptor 0.0005 0.0058 0.0087
Echinococcus multilocularis neuropeptide receptor A26 0.0005 0.0058 0.0058
Brugia malayi neuropeptide F receptor 0.0005 0.0058 0.0087
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0005 0.0058 0.0067
Echinococcus granulosus G protein coupled receptor 139 0.0005 0.0058 0.0058
Schistosoma mansoni amine GPCR 0.0005 0.0058 0.0067
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0204 1 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Schistosoma mansoni neuropeptide receptor 0.0005 0.0058 0.0067
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0535 0.0351
Echinococcus granulosus transient receptor potential cation channel 0.0003 0.000000082652 0.000000082652
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0068 0.3235 0.4907
Schistosoma mansoni amine GPCR 0.0005 0.0058 0.0067
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0535 0.0351
Onchocerca volvulus 0.0014 0.0535 0.0799
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0535 0.0811
Loa Loa (eye worm) RNA binding protein 0.0063 0.2968 0.4502
Brugia malayi hypothetical protein 0.0005 0.0058 0.0087
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0005 0.0058 0.0058
Echinococcus multilocularis tar DNA binding protein 0.0063 0.2968 0.2968
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0058 0.0067
Loa Loa (eye worm) neuropeptide F receptor 0.0005 0.0058 0.0087
Brugia malayi Melatonin receptor type 1A 0.0005 0.0058 0.0087
Schistosoma mansoni histamine h1 receptor 0.0005 0.0058 0.0067
Loa Loa (eye worm) hypothetical protein 0.0014 0.0535 0.0811
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0535 0.0619
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0535 0.0811
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Brugia malayi hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0005 0.0058 0.0087
Brugia malayi Serotonin receptor 0.0005 0.0058 0.0087
Schistosoma mansoni alpha-1 adrenergic receptor 0.0005 0.0058 0.0067
Brugia malayi RNA binding protein 0.0063 0.2968 0.4502
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) G-protein coupled receptor 0.0005 0.0058 0.0087
Onchocerca volvulus 0.0048 0.2237 0.3647
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0005 0.0058 0.0058
Loa Loa (eye worm) TAR-binding protein 0.0063 0.2968 0.4502
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0082 0.3917 0.4529
Schistosoma mansoni hypothetical protein 0.0079 0.3795 0.4388
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Echinococcus multilocularis somatostatin receptor 0.0005 0.0058 0.0058
Echinococcus granulosus tm gpcr rhodopsin 0.0005 0.0058 0.0058
Loa Loa (eye worm) matrixin family protein 0.0135 0.6592 1
Echinococcus multilocularis orexin receptor type 2 0.0005 0.0058 0.0058
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.2237 0.6304
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.2237 0.6304
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Echinococcus multilocularis neuropeptide Y receptor 0.0005 0.0058 0.0058
Loa Loa (eye worm) melatonin receptor type 1A 0.0005 0.0058 0.0087
Brugia malayi GnHR receptor homolog 0.0005 0.0058 0.0087
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0005 0.0058 0.0058
Echinococcus multilocularis neuropeptide s receptor 0.0005 0.0058 0.0058
Loa Loa (eye worm) oxidoreductase 0.0014 0.0535 0.0811
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.2209 0.2209
Echinococcus multilocularis fmrfamide receptor 0.0005 0.0058 0.0058
Echinococcus granulosus 7tm_1 domain containing protein 0.0005 0.0058 0.0058
Echinococcus multilocularis fmrfamide receptor 0.0005 0.0058 0.0058
Echinococcus granulosus alpha 1A adrenergic receptor 0.0005 0.0058 0.0058
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0005 0.0058 0.0058
Echinococcus multilocularis geminin 0.0176 0.8648 0.8648
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0535 0.0351
Brugia malayi Matrixin family protein 0.0056 0.2625 0.3982
Loa Loa (eye worm) matrix metalloproteinase 0.0056 0.2625 0.3982
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0535 0.0811
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0535 0.0351
Schistosoma mansoni neuropeptide F-like receptor 0.0005 0.0058 0.0067
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.1628 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Brugia malayi ORL1-like opioid receptor 0.0005 0.0058 0.0087
Schistosoma mansoni biogenic amine (5HT) receptor 0.0005 0.0058 0.0067
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0005 0.0058 0.0087
Onchocerca volvulus 0.0014 0.0535 0.0799
Mycobacterium ulcerans hypothetical protein 0.0048 0.2237 0.6304
Brugia malayi hypothetical protein 0.0005 0.0058 0.0087
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.1628 0.4257
Loa Loa (eye worm) hypothetical protein 0.0036 0.1628 0.2469
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0058 0.0067
Echinococcus granulosus tm gpcr rhodopsin 0.0005 0.0058 0.0058
Schistosoma mansoni tar DNA-binding protein 0.0063 0.2968 0.3432
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0535 0.0535
Onchocerca volvulus 0.0014 0.0535 0.0799
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0535 0.0811
Schistosoma mansoni adenoreceptor 0.0005 0.0058 0.0067
Onchocerca volvulus Matrix metalloproteinase homolog 0.0124 0.6033 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Echinococcus granulosus peptide allatostatin:somatostatin 0.0005 0.0058 0.0058
Echinococcus granulosus biogenic amine 5HT receptor 0.0005 0.0058 0.0058
Echinococcus multilocularis g protein coupled receptor 0.0005 0.0058 0.0058
Brugia malayi hypothetical protein 0.0005 0.0058 0.0087
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Brugia malayi hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0535 0.0811
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.2237 0.6304
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0058 0.0067
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.2237 0.6304
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.2237 0.6433
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0005 0.0058 0.0058
Echinococcus granulosus neuropeptide receptor 0.0005 0.0058 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0058 0.0067
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0005 0.0058 0.0067
Brugia malayi putative neuropeptide receptor 0.0005 0.0058 0.0087
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0005 0.0058 0.0087
Onchocerca volvulus Matrilysin homolog 0.0124 0.6033 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.2209 0.335
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0535 0.0811
Brugia malayi Dopamine receptor protein 1 0.0005 0.0058 0.0087
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.1628 0.5
Brugia malayi AMP-binding enzyme family protein 0.0048 0.2237 0.3393
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.2237 1
Echinococcus multilocularis allatostatin A receptor 0.0005 0.0058 0.0058
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0535 0.0351
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0535 0.5
Loa Loa (eye worm) neuropeptide F receptor 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0535 0.5
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0005 0.0058 0.0087
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0535 0.5
Schistosoma mansoni neuropeptide receptor 0.0005 0.0058 0.0067
Brugia malayi sulfakinin receptor protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0036 0.1628 0.2469
Echinococcus granulosus fmrfamide receptor 0.0005 0.0058 0.0058
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.2237 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.2237 0.3393
Echinococcus multilocularis dro:myosuppressin receptor 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Schistosoma mansoni opsin-like receptor 0.0005 0.0058 0.0067
Loa Loa (eye worm) hypothetical protein 0.0068 0.3235 0.4907
Echinococcus granulosus neuropeptide s receptor 0.0005 0.0058 0.0058
Echinococcus granulosus neuropeptide FF receptor 2 0.0005 0.0058 0.0058
Schistosoma mansoni opsin-like receptor 0.0005 0.0058 0.0067
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.1628 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0005 0.0058 0.0058
Echinococcus granulosus g protein coupled receptor 0.0005 0.0058 0.0058
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.2237 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0176 0.8648 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.153 0.3905
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.2968 0.4502
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0535 0.0811
Brugia malayi Dopamine receptor protein 2 0.0005 0.0058 0.0087
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0535 0.5
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Brugia malayi Hemopexin family protein 0.0079 0.3795 0.5756
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Brugia malayi Matrixin family protein 0.0056 0.2625 0.3982
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.2209 0.2209
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0005 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0005 0.0058 0.0067
Schistosoma mansoni neuropeptide receptor 0.0005 0.0058 0.0067
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0005 0.0058 0.0067
Schistosoma mansoni tar DNA-binding protein 0.0063 0.2968 0.3432
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Schistosoma mansoni neuropeptide F-like receptor 0.0005 0.0058 0.0067
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0005 0.0058 0.0087
Schistosoma mansoni amine GPCR 0.0005 0.0058 0.0067
Echinococcus granulosus neuropeptide receptor A26 0.0005 0.0058 0.0058
Echinococcus multilocularis serotonin receptor 0.0005 0.0058 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Echinococcus granulosus tachykinin peptides receptor 99D 0.0005 0.0058 0.0058
Schistosoma mansoni neuropeptide receptor 0.0005 0.0058 0.0067
Echinococcus multilocularis g protein coupled receptor 0.0005 0.0058 0.0058
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0535 0.5
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Schistosoma mansoni neuropeptide f receptor 76f 0.0005 0.0058 0.0067
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0005 0.0058 0.0058
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.2209 0.2554
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0005 0.0058 0.0067
Echinococcus granulosus biogenic amine 5HT receptor 0.0005 0.0058 0.0058
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.2237 0.6304
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.153 0.3905
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0535 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0005 0.0058 0.0067
Brugia malayi Tachykinin-like peptides receptor 99D 0.0005 0.0058 0.0087
Echinococcus granulosus g protein coupled receptor 0.0005 0.0058 0.0058
Echinococcus granulosus neuropeptides capa receptor 0.0005 0.0058 0.0058
Echinococcus granulosus g-protein coupled receptor 0.0005 0.0058 0.0058
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.2237 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0005 0.0058 0.0067
Onchocerca volvulus 0.0014 0.0535 0.0799
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0005 0.0058 0.0058
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0535 0.5
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0535 0.0351
Echinococcus granulosus allatostatin A receptor 0.0005 0.0058 0.0058
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0005 0.0058 0.0067
Echinococcus granulosus rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Schistosoma mansoni amine GPCR 0.0005 0.0058 0.0067
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0056 0.2625 0.3036
Schistosoma mansoni hypothetical protein 0.0005 0.0058 0.0067
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0056 0.2625 0.3982
Echinococcus multilocularis G protein coupled receptor 139 0.0005 0.0058 0.0058
Echinococcus granulosus hypothetical protein 0.0005 0.0058 0.0058
Brugia malayi neuropeptide F receptor 0.0005 0.0058 0.0087
Schistosoma mansoni hypothetical protein 0.0005 0.0058 0.0067
Schistosoma mansoni opsin-like receptor 0.0005 0.0058 0.0067
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0005 0.0058 0.0058
Brugia malayi RE15519p 0.0005 0.0058 0.0087
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0005 0.0058 0.0087
Echinococcus granulosus tm gpcr rhodopsin 0.0005 0.0058 0.0058
Echinococcus multilocularis g protein coupled receptor 0.0005 0.0058 0.0058
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0005 0.0058 0.0058
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.2968 0.4502
Schistosoma mansoni tar DNA-binding protein 0.0063 0.2968 0.3432
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0005 0.0058 0.0058
Schistosoma mansoni growth hormone secretagogue receptor 0.0005 0.0058 0.0067
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0535 0.5
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0005 0.0058 0.0067
Echinococcus granulosus somatostatin receptor 0.0005 0.0058 0.0058
Echinococcus granulosus serotonin receptor 0.0005 0.0058 0.0058
Schistosoma mansoni biogenic amine receptor 0.0005 0.0058 0.0067
Loa Loa (eye worm) hypothetical protein 0.0036 0.1628 0.2469
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0005 0.0058 0.0058
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.2237 0.6304
Loa Loa (eye worm) hypothetical protein 0.0056 0.2625 0.3982
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0005 0.0058 0.0087
Mycobacterium ulcerans hydrolase 0.0068 0.3235 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0005 0.0058 0.0058
Brugia malayi G-protein coupled receptor 0.0005 0.0058 0.0087
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0535 0.5
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.2237 0.6304
Echinococcus granulosus g protein coupled receptor 0.0005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Schistosoma mansoni myosin xvIII 0.0005 0.0058 0.0067
Brugia malayi hypothetical protein 0.0005 0.0058 0.0087
Brugia malayi AMP-binding enzyme family protein 0.0048 0.2237 0.3393
Mycobacterium leprae PROBABLE HYDROLASE 0.0068 0.3235 1
Schistosoma mansoni hypothetical protein 0.0176 0.8648 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Brugia malayi Matrixin family protein 0.0056 0.2625 0.3982
Onchocerca volvulus 0.0079 0.3795 0.6254
Loa Loa (eye worm) TYRA-2 protein 0.0005 0.0058 0.0087
Echinococcus granulosus neuropeptide receptor 0.0005 0.0058 0.0058
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0005 0.0058 0.0067
Echinococcus multilocularis g-protein coupled receptor 0.0005 0.0058 0.0058
Brugia malayi follicle stimulating hormone receptor 0.0005 0.0058 0.0087
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.2237 0.6304
Loa Loa (eye worm) hypothetical protein 0.0005 0.0058 0.0087
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0535 0.0351

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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