Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.2616 | 0.9575 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0739 | 0.216 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0739 | 0.2714 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.2724 | 0.0146 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.2724 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0739 | 0.2714 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.2724 | 0.0146 |
Echinococcus multilocularis | geminin | 0.0177 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0066 | 0.2616 | 0.9458 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.2616 | 0.9458 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.2724 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.2724 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.2724 | 0.0146 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0931 | 0.3419 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.2616 | 0.9458 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.2724 | 0.0146 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.2616 | 0.9575 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0739 | 0.7399 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0931 | 0.3419 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0931 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.2724 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.2616 | 0.9575 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.2724 | 0.0146 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 1 | 1 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.2724 | 0.0146 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.